CN103385975A - Traditional Chinese medicine for treating thrombocytopenia - Google Patents

Traditional Chinese medicine for treating thrombocytopenia Download PDF

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Publication number
CN103385975A
CN103385975A CN2013102780022A CN201310278002A CN103385975A CN 103385975 A CN103385975 A CN 103385975A CN 2013102780022 A CN2013102780022 A CN 2013102780022A CN 201310278002 A CN201310278002 A CN 201310278002A CN 103385975 A CN103385975 A CN 103385975A
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medicine
radix
blood
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CN103385975B (en
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冯子政
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Beijing Gulou Research Institute Of Difficult Diseases Co Ltd
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Abstract

A traditional Chinese medicine for treating thrombocytopenia is characterized in that the medicine for one treatment course is prepared by the following raw materials: 50-100 g of charred honeysuckle, 50-100 g of charred herba schizonepetae, 150-300 g of radix astragali, 150-300 g of radix codonopsis, 50-100 g of bighead atractylodes rhizome, 100-200 g of jujube, 150-300 g of raw rehmannia root, 100-200 g of cortex lycii, 100-200 g of white peony root and 100-200 g of wolfberry. Based on simultaneous treatment of principal and subordinate symptoms, complementation of nutrient and defense, and co-nourishing of qi and blood, the medicine helps platelets to have regenerative growth, helps a patient to have normal physiology and helps the platelets to synchronously recover normal. The medicine helps to finish blood regeneration function through liver, spleen and kidney.

Description

The Chinese medicine for the treatment of thrombocytopenia
One, technical field
The present invention relates to a kind of treat thrombocytopenia medicine.
Two, background technology
Platelet (blood platelet) is one of visible component in mammalian.Out-of-shape, more much smaller than erythrocyte and leukocyte, acellular core, in adult's blood, platelet counts is (1-3) * 100 * 10 9/ L, it has plasma membrane, there is no the nucleus structure, and is generally rounded, and volume is less than erythrocyte and leukocyte.Platelet has specific morphosis and biochemical composition, more constant quantity (platelet count as the people is every cubic millimeter 10~300,000) is arranged in normal blood, play an important role in the physiology such as hemostasis, wound healing, inflammatory reaction, thrombosis and organ-graft refection and pathological process.Hematoblastic major function is blood coagulation and hemostasis, repairs damaged blood vessel.When platelet count<100 * 110 9/ L is thrombocytopenia, is common in the thrombocytopoiesis obstacle, as aplastic anemia, and acute leukemia, acute radiation sickness etc.; Platelet destruction increases, and as idiopathic thrombocytopenic purpura, hypersplenism, overrun as disseminated inravascular coagulation, familial thrombocytopenia such as bernard-Soulier syndrome etc.A lot of medical workers study for this reason and have paid energy throughout one's life, have developed multi-medicament, but curative effect is not remarkable mostly.
Common thrombocytopenia prescription has:
Prescriptions of Chinese medicine (one): Cornu rhinocerotis 3 grams, the Radix Rehmanniae 30 grams, Cortex Moutan 10 grams, Radix Paeoniae Rubra 10 grams, Radix Cynanchi Atrati 10 grams, Radix Arnebiae (Radix Lithospermi) 10 grams, the Rhizoma Anemarrhenae 10 grams, Radix Adenophorae (Radix Glehniae) 10 grams, Flos Sophorae 30 grams, Folium Isatidis 10 grams, Radix Isatidis 15 grams.
Prescriptions of Chinese medicine (two): the Radix Rehmanniae 10 grams, Radix Paeoniae Alba 30 grams, Herba Ecliptae 15 grams, Rhizoma Dioscoreae 20 grams, lotus rice 15 grams, Fructus Forsythiae 10 grams, Semen Phaseoli 30 grams, Rhizoma Coptidis 6 grams, Herba Lophatheri 10 grams, Fructus Schisandrae Chinensis 10 grams, Fructus Corni 10 grams, 10, Fructus Jujubae, Radix Glycyrrhizae Preparata 10 grams.
Prescriptions of Chinese medicine (three): Caulis Spatholobi 15 grams, Cortex Moutan 15 grams, Radix Rubiae 15 grams, Radix Angelicae Sinensis 15 grams, Fructus Jujubae 10 grams, Rhizoma Imperatae 15 grams, Herba Ecliptae 20 grams, Radix Notoginseng powder 5 grams (taking after mixing it with water), Herba Agrimoniae 20 grams, Fructus Gardeniae 15 grams.In addition:
The Patent Application Publication of application number CN201310017355 a kind of thrombocytosis Chinese medicine composition and preparation method thereof, this Chinese medicine composition be by Indigo Naturalis, Fructus Forsythiae, Herba Agrimoniae, Cortex Moutan, Radix Glycyrrhizae altogether Chinese medicine of the five flavours be prepared from; This medical instrument has heat-clearing and toxic substances removing, cooling blood for hemostasis, the effect of dissipating blood stasis speckle removing; Be mainly used in idiopathic thrombocytopenic purpura; Disease is seen: whole body petechia or ecchymosis, and the heating excessive thirst, oliguria with reddish urine, constipation, or see epistaxis, bleeding from the gum, red tongue with yellow fur, slippery and rapid pulse or stringy and rapid pulse.
The Patent Application Publication of application number CN201210570569 a kind of pharmaceutical composition for the treatment of thrombocytopenia, said composition is by Radix Ginseng, Herba Epimedii, the Radix Astragali, Radix Angelicae Sinensis, Radix Rehmanniae Preparata, Caulis Spatholobi, Herba Agrimoniae and Pericarpium Citri Reticulatae form.
The Patent Application Publication of application number CN201210483181 the medicine for the treatment of hematopathy idiopathic thrombocytopenic purpura, this invention medicine is made by following component: Semen Oroxyli 30 grams, Radix Scutellariae 50 grams, Cortex Phellodendri 75 grams, Radix Gentianae 40 grams, Folium Isatidis 75 grams, Radix Isatidis 50 grams, Rhizoma Belamcandae 60 grams, Rhizoma Coptidis 75 grams, Herba Scutellariae Barbatae 200 grams, Herba Lobeliae Chinensis 150 grams, Herba Salviae Chinensis 60 grams, Pseudobulbus Cremastrae Seu Pleiones 50 grams; Above-mentioned each component mix homogeneously is ground into 150 order fine powders, is distributed into bag, every packed medicated powder 6 grams.One after each meal.
Three, summary of the invention
The objective of the invention is to overcome the deficiencies in the prior art, develop a kind of Chinese medicine for the treatment of thrombocytopenia evident in efficacy.
Prescription of the present invention and dosage are:
A kind of Chinese medicine for the treatment of thrombocytopenia is characterized in that the medicine of a course for the treatment of is made by following medicine material:
Charred Flos Lonicerae 50-100 gram, Herba Schizonepetae charcoal 50-100 gram, Radix Astragali 150-300 gram, Radix Codonopsis 150-300 gram, Rhizoma Atractylodis Macrocephalae 50-100 gram, Fructus Jujubae 100-200 gram, Radix Rehmanniae 150-300 gram, Cortex Lycii 100-200 gram, Radix Paeoniae Alba 100-200 gram, Fructus Lycii 100-200 gram.
Said medicine can adopt the conventional method of Chinese drug preparation to make ball, tablet or capsule and swallow, and is taken three times a day, each 6 grams of being grown up, and the child reduces by half; Also can adopt conventional decoction mode.Most patients is taken the medicine of a course for the treatment of and just can be fully recovered, and the medicine of two to three courses for the treatment of of patient with severe symptoms also can be fully recovered.
The property of medicine and function: Flos Lonicerae, sweet trembling with fear into the lung heart, heat-clearing and toxic substances removing, dispelling wind and heat pathogens, charcoal is directly joined the army and is defended, loose wind hemostasis; Herba Schizonepetae, hot tepor, return lung, liver, delivers loose wind, and charcoal goes suffering, enters nutrient blood and goes the wind hemostasis; The Radix Astragali is sweet, tepor, returns the spleen lung, invigorating QI to consolidate the body surface resistance; Radix Codonopsis is sweet flat, returns the spleen lung, invigorating middle warmer gas and nourishing blood; The Rhizoma Atractylodis Macrocephalae is sweet, bitter, warm, return the taste warp, air making-up and spleen enlivening, dampness diuresis; The sweet temperature of Fructus Jujubae, return taste, and invigorating middle warmer gas is supported the spleen stomach function regulating; Radix Rehmanniae, sweet, bitter, cold, GUIXIN liver, kidney channel, clearing away heat and cooling blood, YIN nourishing and the production of body fluid promoting; Cortex Lycii, sweet, light, tremble with fear, return lung, kidney channel, removing heat from blood to move back steaming, clean lung-heat; The Radix Paeoniae Alba is sweet cold and sour, returns the liver spleen, the hepatoprotective that nourishes blood, and store blood, hemostasis is received in acid; Fructus Lycii, sweetly put down, return liver, kidney, lung meridian, the lung moistening of holding concurrently of the kidney invigorating and essence nourishing, nourishing the liver to improve visual acuity.
The present invention is in line with treating both the principal and the secondary aspects of a disease at the same time, and battalion defends complementation, and QI and blood is supported altogether, thereby makes the blood platelet regenerating growth, awards physiology normal, and platelet is synchronous recovers normal.Solved doctors and patients' blood for a difficult difficult problem, so both alleviated government and mobilized the pressure of blood donation personnel, reduced again patient's financial burden, the doctor also worries without blood supply insufficiency.
The present invention has removed the blood regeneration function by liver spleen kidney.
The dosage of above-mentioned prescription, be the dosage safely and effectively of deciding through test of many times, clinical practice, surpasses the upper limit and may produce certain toxic and side effects, and is not obvious lower than floor effect.Can send the medicine compatibility, be required to be use mutually according to dissimilar thrombocytopenia symptom prescription.
Four, the specific embodiment
Below provide the present invention 6 prescription embodiments (in following table unit be quality g) different according to the conditions of patients light and heavy degree:
Composition Example 1 Example 2 Example 3 Example 4 Example 5 Example 6
Charred Flos Lonicerae 100 90 80 70 60 50
Herba Schizonepetae charcoal 80 70 50 65 95 100
The Radix Astragali 150 180 250 190 280 300
Radix Codonopsis 240 190 250 300 150 250
The Rhizoma Atractylodis Macrocephalae 60 75 85 90 50 100
Fructus Jujubae 160 110 100 150 145 200
Radix Rehmanniae 150 180 290 260 230 300
Cortex Lycii 160 180 130 150 100 200
The Radix Paeoniae Alba 200 100 175 160 140 120
Fructus Lycii 180 150 100 200 170 130
Model case is described as follows:
Example one: the female employee of Mianyang City institute, 28 years old, thrombocytopenia, whole body subcutaneous hemorrhage, skin becomes black entirely, tongue body black, and double eyeball is congested, visceral hemorrhage, haematemesis disease blood is serious, the unable support of patient, be considered as refractory danger disease at several large hospitals, arrive upon somebody's introduction the inventor place, after inventor's diagnosis to having opened the decoction of the present invention decoction of going home, become and come to the 3rd day skin color, tongue is not black, and the blood of eyeball has also moved back, do not spitted blood disease blood again, had a meal, spirit might as well.The inventor opens after a course for the treatment of, pill of the present invention was taken again, goes hospital's check, reports the result, and recovers normal fully.
Example two: the Qin so-and-so, the female, 43 years old, Mianyang Youxian District people, because of thrombocytopenia, oral hemorrhage, dental hemorrhage, treat several Nian Weiyu.Come upon somebody's introduction the inventor to locate to seek medical advice, take a course for the treatment of with pill of the present invention complete good, go to hospital to check that all are normal.
Example three: one spadger of slab bridge community, Economic Development Zone, Mianyang, 2 years old is more, and because of thrombocytopenia, hospitalization is many half a year, and platelet almost arrives zero as a result.Child's whole face is blood, and whole body is all purpura everywhere, the hormone body constitution of a large face of major part, and systemic conditions is not so good.After inventor's diagnosis, take a course for the treatment of (one and a half months) by each 3 gram 3 pills of the present invention every day of child dose, go hospital's check, all recover normal the proof of reporting the result.
During the last ten years through the inventor with hundreds of person-times of the thrombocytopenia patients of this Drug therapy, do not heal.

Claims (1)

1. Chinese medicine for the treatment of thrombocytopenia, the medicine that it is characterized in that a course for the treatment of is made by following medicine material: charred Flos Lonicerae 50-100 gram, Herba Schizonepetae charcoal 50-100 gram, Radix Astragali 150-300 gram, Radix Codonopsis 150-300 gram, Rhizoma Atractylodis Macrocephalae 50-100 gram, Fructus Jujubae 100-200 gram, Radix Rehmanniae 150-300 gram, Cortex Lycii 100-200 gram, Radix Paeoniae Alba 100-200 gram, Fructus Lycii 100-200 gram.
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103690692A (en) * 2013-11-29 2014-04-02 周晨 Traditional Chinese medicine formula for treating purpura

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1048498A (en) * 1989-12-30 1991-01-16 白璋华 The manufacture method of the compositions of treatment immunologic function deficiency disease
CN1319403A (en) * 2000-11-01 2001-10-31 王志好 Medicine for treating allergic purpura
CN1539459A (en) * 2003-10-30 2004-10-27 吉林省辽源亚东药业股份有限公司 Chinese materia medica preparation of recreating blood for curing anaemia and producing method
CN101264220A (en) * 2008-05-04 2008-09-17 北京中科仁和科技有限公司 Medicaments assembly for tonifying kidney and invigorating spleen, activating blood circulation and removing stasis and preparation thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1048498A (en) * 1989-12-30 1991-01-16 白璋华 The manufacture method of the compositions of treatment immunologic function deficiency disease
CN1319403A (en) * 2000-11-01 2001-10-31 王志好 Medicine for treating allergic purpura
CN1539459A (en) * 2003-10-30 2004-10-27 吉林省辽源亚东药业股份有限公司 Chinese materia medica preparation of recreating blood for curing anaemia and producing method
CN101264220A (en) * 2008-05-04 2008-09-17 北京中科仁和科技有限公司 Medicaments assembly for tonifying kidney and invigorating spleen, activating blood circulation and removing stasis and preparation thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
禹正玲: "儿童紫癜的中药对应治疗的选择——附70例小结", 《贵阳中医学院学报》, vol. 14, no. 2, 30 April 1992 (1992-04-30), pages 21 - 23 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103690692A (en) * 2013-11-29 2014-04-02 周晨 Traditional Chinese medicine formula for treating purpura

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Address after: 102200 Room 204, floor 104, floor 1-4, building 2, Tiantong Xiyuan District 3, Dongxiaokou Town, Changping District, Beijing

Patentee after: Beijing Gulou Research Institute of difficult diseases Co., Ltd

Address before: 621000 Sichuan city of Mianyang province of Banqiao Street nephropathy open area mianzhou North Avenue No. 13

Patentee before: Feng Zizheng

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