CN103385736B - Inner peeping type nasopharyngeal carcinoma supersonic imaging device - Google Patents
Inner peeping type nasopharyngeal carcinoma supersonic imaging device Download PDFInfo
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- CN103385736B CN103385736B CN201310330411.2A CN201310330411A CN103385736B CN 103385736 B CN103385736 B CN 103385736B CN 201310330411 A CN201310330411 A CN 201310330411A CN 103385736 B CN103385736 B CN 103385736B
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/12—Diagnosis using ultrasonic, sonic or infrasonic waves in body cavities or body tracts, e.g. by using catheters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
- A61B1/233—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the nose, i.e. nasoscopes, e.g. testing of patency of Eustachian tubes
Abstract
The present invention relates to a kind of inner peeping type nasopharyngeal carcinoma supersonic imaging device.Described device comprises: photographic head, for gathering the organism optical image of nasopharynx inner surface; Video signal processing unit, for being converted into video signal by described organism optical picture signal; Control and image-generating unit, for preserving and showing described digital signal, and send control instruction; Ultrasonic action and receiving element, produce specific pulse signal according to ultrasonic control instruction and carry out ultrasonic action, carries out ultrasonoscopy display after receiving element process ultrasound echo signal simultaneously; Ultrasonic transducer, for producing the Endonasopharyngeal ultrasound wave of scanning according to described pulse signal, and receives ultrasound echo signal, and described ultrasound echo signal is converted into electric echo signal; Described ultrasonic action and receiving element are also for processing described electric echo signal; And described control and image-generating unit are also for carrying out ultra sonic imaging according to the described electric echo signal after processing.Improve the accuracy of detection.
Description
Technical field
The present invention relates to medical apparatus and instruments, particularly relate to a kind of inner peeping type nasopharyngeal carcinoma supersonic imaging device.
Background technology
Nasopharyngeal carcinoma is the malignant tumor being primary in nasopharynx position.Nasopharyngeal Carcinoma Patients about 600,000 is newly sent out in the whole world every year, occupies Cancer Mortality the 5th.Nasopharyngeal carcinoma early symptom is not obvious, and middle and advanced stage symptom comprises blood tears, bloody sputum, tinnitus, deafness, cervical lymph enlargement, headache, facial numbness, diplopia, blepharoptosis, blind, dysphagia, hoarseness, loll deflection etc.Most symptom can not cause patient suffering to experience, and symptom that is easy and other causes of disease is obscured; Usually, nasopharyngeal carcinoma is apt to occur in the mucosa of nasopharynx inwall, and this position is more hidden, and conventional indirect nasopharyngeal mirror is difficult to accurate discrimination cancerous issue.Therefore very easily out in the cold or mistaken diagnosis at the beginning of nasopharyngeal carcinoma morbidity.Because the vital tissue organs such as nasopharynx and brain, intracranial vessel, lymph node, nerve are close, originate from the cancer in situ of mucous membrane of nasopharynx, be easy to invade the vital tissue organs such as brain, even transfer to liver at a distance, lung and bone by lymphatic vessel, blood vessel.This is the major reason causing NPC mortality higher.Early find that early treatment is the Key Principles preventing and treating nasopharyngeal carcinoma.
According to the pathological characteristics of tumor cell, nasopharyngeal carcinoma can be divided into cancer in situ, micro-infiltrating carcinoma, squamous cell carcinoma, adenocarcinoma, vesicular nucleus cell carcinoma and undifferentiated carcinoma.Different according to the profile of nasopharyngeal carcinoma, nodular type, fungating type, infiltrative type, ulcer type and mucosa mo(u)ld bottom half can be divided into.For doing unified assessment to tumor invading scope, normal employing TNM standard is (namely according to the degree of other histoorgans of comprehensive assessment tumor invading, the degree of the contiguous lymph node of tumor invading, neoplasm metastasis is to the scope at other positions), tumor is divided into I, II, III, IV a, IV b five phase.TNM by stages more after, then represent that tumor invading, metastasis degree are higher, the treatment survival rate of patient is lower.Because nasopharyngeal carcinoma cell is very responsive to high-energy ray, therefore radiotherapy is the Main Means for the treatment of nasopharyngeal carcinoma.Before implementing radiotherapy, the imaging methods such as CT, MRI need be adopted accurately to locate range of tumor, to determine position and the dosage of x radiation x.
But CT imaging technique, density resolution is high, and being applicable to bone or calcified tissue's imaging, is then its weakness for human body soft tissue imaging.Canceration or Fibrotic mucous membrane of nasopharynx tissue, though can be identified roughly in CT imaging, the tissue variation of trickle (as diameter is less than 1 millimeter), is but difficult to by reliable recognition.MRI technology, properties is all better than CT imaging technique, but its diagnosis somewhat expensive, taboo be used for health be implanted into metal or magnetic material patient, wait deficiency to the tissue of trickle (as diameter is less than 1 millimeter) variation is insensitive.
Summary of the invention
Based on this, be necessary to detect coarse problem for current to the device that nasopharynx detects, a kind of inner peeping type nasopharyngeal carcinoma supersonic imaging device that can improve accuracy in detection is provided.
In addition, there is a need to provide a kind of inner peeping type nasopharyngeal carcinoma ultrasonic imaging method that can improve accuracy in detection.
A kind of inner peeping type nasopharyngeal carcinoma supersonic imaging device, comprising:
Photographic head, for gathering the organism optical image of nasopharynx inner surface;
Video signal processing unit, is connected with described photographic head, is converted into digital signal for carrying out process to the organism optical image of described collection;
Control and image-generating unit, be connected with described video signal processing unit, for preserving and showing described digital signal, and send control instruction;
Ultrasonic action and receiving element, be connected with image-generating unit with described control, for receiving the control instruction that described control and image-generating unit send, and produces specific pulse signal according to described control instruction;
Ultrasonic transducer, be connected with receiving element with described ultrasonic action, for producing the Endonasopharyngeal ultrasound wave of scanning according to described pulse signal excitation, and receive the ultrasound echo signal of described nasopharynx internal reflection, and described ultrasound echo signal is converted into electric echo signal, and described electric echo signal is sent to described ultrasonic action and receiving element;
Electric echo signal after process also for processing described electric echo signal, and is transferred to described control and image-generating unit by described ultrasonic action and receiving element; And
Described control and image-generating unit also for carrying out ultra sonic imaging according to the described electric echo signal after processing, and obtain video image according to described digital signal, guide and location described ultrasonic transducer according to described video image.
Wherein in an embodiment, described ultrasonic action and receiving element comprise the excitation and data processor, pulse driver, impulse sender, high-voltage switch gear, low-noise amplifier, wave filter, A/D converter that are connected successively, described excitation is connected with image-generating unit with described control with data processor, and described high-voltage switch gear is connected with described ultrasonic transducer;
The control instruction that described excitation and data processor send for receiving described control and image-generating unit, and control described pulse driver according to described control instruction and pulse generator produces specific pulse signal, and described pulse signal is transferred to described ultrasonic transducer through described high-voltage switch gear, produce ultrasound wave to encourage described ultrasonic transducer;
The described electric echo signal that described ultrasonic transducer transforms, after described high-voltage switch gear switching, after described low-noise amplifier, wave filter, A/D converter, excitation and data processor processes, is transferred to described control and image-generating unit.
Wherein in an embodiment, described ultrasonic action and receiving element carry out process to described electric echo signal and comprise and adopt at least one in digital filtering algorithm, time gain compensation algorithm, envelope detection algorithm, digital scan conversion algorithm, doppler frequency spectrum analysis algorithm, algorithm for image enhancement to process.
Wherein in an embodiment, described control and image-generating unit comprise man-machine interaction subelement, video signal Storage & Display subelement, control subelement, activation sequence generating subunit, buffer memory subelement and multiparameter ultra sonic imaging subelement, and described activation sequence generating subunit is connected with receiving element with described ultrasonic action respectively by data-interface with buffer memory subelement;
Described video signal Storage & Display subelement is for receiving the digital signal of described video signal processing unit transmission;
Described imaging control parameters for receiving the imaging control parameters of input, and is transferred to described control subelement and described activation sequence generating subunit to produce pulse train by described man-machine interaction subelement;
Described activation sequence generating subunit is used for described pulse train to send to described ultrasonic action and receiving element by data-interface;
Described buffer memory subelement is used for receiving and storing described electric echo signal, and described electric echo signal is transferred to described multiparameter ultra sonic imaging subelement;
Described multiparameter ultra sonic imaging subelement is used for carrying out multi-parameter fusion imaging according to described electric echo signal, and described multi-parameter fusion imaging is presented at described man-machine interaction subelement.
Wherein in an embodiment, described ultrasonic transducer comprises multiple Under Ultrasonic Vibration unit, and each Under Ultrasonic Vibration unit comprises piezoelectric and two battery lead plates of cutting half separation.
Wherein in an embodiment, the frequency of described specific pulse signal is 10MHz ~ 60MHz.
A kind of inner peeping type nasopharyngeal carcinoma ultrasonic imaging method, comprising:
Initialization step, provides photographic head connected successively, video signal processing unit, control and image-generating unit, ultrasonic action and receiving element and ultrasonic transducer;
Video acquisition step, by the organism optical image of described camera collection nasopharynx inner surface, digital signal is converted into through described video signal processing unit, preserve and show described digital data transmission to described control and image-generating unit, according to described digital signal, described ultrasonic transducer is guided and location;
Produce pulse signal step, send control instruction by described control and image-generating unit, control described ultrasonic action and receiving element produces specific pulse signal;
Scanning step, the Endonasopharyngeal ultrasound wave of scanning is produced according to described pulse signal excitation by described ultrasonic transducer, and the ultrasound echo signal of described nasopharynx internal reflection is received by described ultrasonic transducer, and described ultrasound echo signal is converted into electric echo signal, and described electric echo signal is sent to described ultrasonic action and receiving element;
Revise step, described electric echo signal is processed; And
Image-forming step, carries out ultra sonic imaging according to the described electric echo signal after described process.
Wherein in an embodiment, described ultrasonic action and receiving element comprise the excitation and data processor, pulse driver, impulse sender, high-voltage switch gear, low-noise amplifier, wave filter, A/D converter that are connected successively, described excitation is connected with image-generating unit with described control with data processor, and described high-voltage switch gear is connected with described ultrasonic transducer;
Described generation pulse signal step comprises:
The control instruction that described control and image-generating unit send is received by described excitation and data processor, and control described pulse driver according to described control instruction and pulse generator produces specific pulse signal, and described pulse signal is transferred to described ultrasonic transducer through described high-voltage switch gear, produce ultrasound wave to encourage described ultrasonic transducer;
Described correction step comprises:
The described electric echo signal transformed by described ultrasonic transducer, after described high-voltage switch gear switching, after described low-noise amplifier, wave filter, A/D converter, excitation and data processor processes, is transferred to described control and image-generating unit.
Wherein in an embodiment, described correction step comprises:
To described echo-signal carry out process comprise adopt digital filtering algorithm, time gain compensation algorithm, envelope detection algorithm, digital scan conversion algorithm, doppler frequency spectrum analysis algorithm, at least one processes in algorithm for image enhancement.
Wherein in an embodiment, the frequency of described specific pulse signal is 10MHz ~ 60MHz.
Above-mentioned inner peeping type nasopharyngeal carcinoma supersonic imaging device and method, by camera collection organism optical image, video image is provided to be that ultrasonic transducer guides and locates, adopt ultrasonic transducer to nasopharynx inwall soft-tissue imaging, realize the full degree of depth accurately image of nasopharynx inwall soft tissue, improve the accuracy of detection.And traditional nasopharynx scope adopts optical imaging modalities, the color on nasopharynx inwall top layer, gloss and shape information can only be observed.
In addition, cost of manufacture is not high, and cost of equipment maintenance is cheap, therefore low to patient's inspection fee, and adopts ultrasonic as imaging media, does not have the ionizing radiation that high-energy rays causes.
Accompanying drawing explanation
Fig. 1 is the structural representation of inner peeping type nasopharyngeal carcinoma supersonic imaging device in an embodiment;
Fig. 2 is the schematic diagram that inner peeping type nasopharyngeal carcinoma supersonic imaging device is applied to the imaging of nasopharyngeal carcinoma predilection site;
Fig. 3 is the schematic diagram of ultrasonic transducer to cavum nasopharyngeum inwall soft-tissue imaging;
Fig. 4 is the internal structure schematic diagram of ultrasonic action and receiving element in an embodiment;
Fig. 5 controls the internal structure schematic diagram with image-generating unit in an embodiment;
Fig. 6 is the flow chart of inner peeping type nasopharyngeal carcinoma ultrasonic imaging method in an embodiment.
Detailed description of the invention
Below in conjunction with specific embodiment and accompanying drawing, the technical scheme to inner peeping type nasopharyngeal carcinoma supersonic imaging device and method is described in detail, to make it clearly.
As shown in Figure 1, be the structural representation of inner peeping type nasopharyngeal carcinoma supersonic imaging device in an embodiment.This inner peeping type nasopharyngeal carcinoma supersonic imaging device, comprises photographic head 110 connected successively, video signal processing unit 120, control and image-generating unit 130, ultrasonic action and receiving element 140 and ultrasonic transducer 150.
Wherein, photographic head 110 is for gathering the organism optical image of nasopharynx inner surface.
In the present embodiment, photographic head 110 adopts high-definition camera.This photographic head 110 can stretch in nasopharynx through nostril, realizes the high definition optical imagery to nasopharynx inner surface, to gather the organism optical image of nasopharynx inner surface.
Video signal processing unit 120 is converted into digital signal for carrying out process to the organism optical image of this collection, and by the digital data transmission after process to controlling and image-generating unit 130.
Control with image-generating unit 130 for optimizing, preserve and showing this digital signal, and obtain video image according to this digital signal, according to this video image, ultrasonic transducer 150 is guided and located.Control also to send control instruction with image-generating unit 130, and control instruction is transferred to ultrasonic action and receiving element 140.
Ultrasonic action and receiving element 140 for receiving the control instruction controlling to send with image-generating unit 130, and produce specific pulse signal according to this control instruction.The frequency of this pulse signal is 10MHz (megahertz) ~ 60MHz.
Ultrasonic transducer (ultrasonic probe) 150 is for producing the Endonasopharyngeal ultrasound wave of scanning according to the excitation of this pulse signal, and receive the ultrasound echo signal of this nasopharynx internal reflection, and this ultrasound echo signal is converted into electric echo signal, and this electric echo signal is sent to ultrasonic action and receiving element 140.In the present embodiment, ultrasonic transducer 150 comprises multiple Under Ultrasonic Vibration unit.
Electric echo signal after process also for processing electric echo signal, and is transferred to control and image-generating unit 130 by ultrasonic action and receiving element 140.
In the present embodiment, ultrasonic action and receiving element 140 carry out process to this electric echo signal and comprise and adopt at least one in digital filtering algorithm, time gain compensation algorithm, envelope detection algorithm, digital scan conversion algorithm, doppler frequency spectrum analysis algorithm, algorithm for image enhancement to process.Wherein, digital filtering algorithm, by arranging suitable filter parameter, carries out bandpass filtering to input radio frequency signal, filter away high frequency noise and low-frequency interference signal; Time gain compensation algorithm, regulates not the gain of echo-signal in the same time, makes the echo-signal of the different tissues degree of depth obtain different gain compensations according to preset rules, ensure the concordance of different depth signal intensity; Envelope detection algorithm, adopts Hilbert transform, obtains the amplitude of radiofrequency signal, and removes high frequency carrier composition; Digital scan conversion algorithm, the data of pressing polar coordinate collection and preservation, by spatial recomposition and interpolation arithmetic, is transformed into the data save mode by rectangular coordinate, so that follow-up display; Doppler frequency spectrum analysis algorithm, be two-way orthogonal data by Hilbert transform radio-frequency echo wave transformation of data, then chosen the data of certain depth by low pass filter and window filter timing, converted by complex fast Fourier, output spectrum data, for showing velocity of blood flow information.
Control with image-generating unit 130 also for carrying out ultra sonic imaging according to the electric echo signal after processing.
Above-mentioned inner peeping type nasopharyngeal carcinoma supersonic imaging device is applied to the imaging of nasopharyngeal carcinoma predilection site, and as shown in Figure 2, ultrasonic transducer 150 stretches in cavum nasopharyngeum, and 22 is that nasal cavity, 24 is for nasopharyngeal carcinoma predilection site.Be illustrated in figure 3 the schematic diagram of ultrasonic transducer to cavum nasopharyngeum inwall soft-tissue imaging, cavum nasopharyngeum inwall has shallowly often can be divided into mucous layer, fibrous layer, Musclar layer and fascia layer to mastering.
Above-mentioned inner peeping type nasopharyngeal carcinoma supersonic imaging device, by camera collection organism optical image, video image is provided to be that ultrasonic transducer guides and locates, adopt ultrasonic transducer to nasopharynx inwall soft-tissue imaging, realize the full degree of depth accurately image of nasopharynx inwall soft tissue, improve the accuracy of detection.And traditional nasopharynx scope adopts optical imaging modalities, the color on nasopharynx inwall top layer, gloss and shape information can only be observed.
As shown in Figure 4, be the internal structure schematic diagram of ultrasonic action and receiving element 140 in an embodiment.This ultrasonic action and receiving element 140 comprise the excitation and data processor 141, pulse driver 142, pulse generator 143, high-voltage switch gear 144, low-noise amplifier 145, wave filter 146, A/D converter 147 that are connected successively.Encourage and be connected with image-generating unit 130 with control by data-interface 160 with data processor 141, high-voltage switch gear 144 is connected with ultrasonic transducer 150.
Excitation and data processor 141 are for receiving the control instruction controlling to send with image-generating unit 130, and produce specific pulse signal according to this control instruction control impuls driver 142 and pulse generator 143, and this pulse signal is transferred to ultrasonic transducer 150 through high-voltage switch gear 144, produce ultrasound wave to encourage ultrasonic transducer 150.Pulse driver 142 is that the pulse generator 143 of next stage does the large process of signal prevention.The similar power amplifier of pulse generator 143 or high-power electronic switch.
Ultrasonic transducer 150 receives the ultrasound echo signal of nasopharynx internal reflection, and this ultrasound echo signal is converted into electric echo signal, and by this electric echo signal after high-voltage switch gear 144 is transferred, after low-noise amplifier 145, wave filter 146, A/D converter 147, excitation and data processor 141 process, be transferred to and control and image-generating unit 130.
Wherein, low-noise amplifier 145 pairs of electric echo signal carry out processing and amplifying, and wave filter 146 pairs of electric echo signal carry out Filtering Processing, and the electric echo signal of simulation is converted into the electric echo signal of numeral by A/D converter 147.This excitation and data processor 141 carry out time gain compensation algorithm process to the electric echo signal of numeral, envelope detection algorithm process, digital scan conversion algorithm process, doppler frequency spectrum analysis algorithm process, image increase algorithm process etc.Electric echo signal after processed is transferred to by data-interface and controls and image-generating unit 130.In addition, excitation and data processor 141 also carry out light beam to the electric echo signal of numeral and synthesize and process.
As shown in Figure 5, control to comprise with image-generating unit 130 be connected successively video signal Storage & Display subelement 131, man-machine interaction subelement 132, control subelement 133, activation sequence generating subunit 134, buffer memory subelement 135 and multiparameter ultra sonic imaging subelement 136.Wherein, activation sequence generating subunit 134 is connected with receiving element 140 with ultrasonic action respectively by data-interface 160 with buffer memory subelement 135.Video signal Storage & Display subelement 131 is connected with video signal processing unit 120.
The digital signal that video signal Storage & Display subelement 131 transmits for receiving video signal processing unit 120.
This imaging control parameters for receiving the imaging control parameters of input, and is transferred to and controls subelement 133 and activation sequence generating subunit 134 to produce pulse train by man-machine interaction subelement 132.This imaging control parameters refers to that excitation produces the parameter of pulse train, as the pulse period.Man-machine interaction subelement 132 comprises the interactive devices such as keyboard, mouse, touch screen, display.
Activation sequence generating subunit 134 is for sending to ultrasonic action and receiving element 140 by this pulse train by data-interface.
This electric echo signal for receiving and storing this electric echo signal, and is transferred to this multiparameter ultra sonic imaging subelement 136 by buffer memory subelement 135.
This multi-parameter fusion imaging for carrying out multi-parameter fusion imaging according to this electric echo signal, and is presented at man-machine interaction subelement 132 by multiparameter ultra sonic imaging subelement 136.This multiparameter comprises B-MODE imaging parameters, frequency spectrum parameter, blood flow Doppler frequency shift parameter etc.This multi-parameter fusion imaging is imaged as master with B ultrasonic.Man-machine interaction subelement 132 can show the real-time color image that photographic head 110 gathers and the ultrasonic B ultrasonic image carrying out ultra sonic imaging according to electric echo signal.
Above-mentioned inner peeping type nasopharyngeal carcinoma supersonic imaging device, cost of manufacture is not high, and cost of equipment maintenance is cheap, therefore low to patient's inspection fee, and adopts ultrasonic as imaging media, does not have the ionizing radiation that high-energy rays causes.
In addition, above-mentioned inner peeping type nasopharyngeal carcinoma supersonic imaging device can be applicable to early stage triggering nasopharyngeal carcinoma and detects, if because tumor tissues grows in mucosa, and also do not cause the obvious profile variation of nasopharynx inwall, then no matter adopt nasopharyngeal endoscope or CT or MRI is all difficult to carry out imaging to nasopharyngeal carcinoma, and adopt this inner peeping type nasopharyngeal carcinoma supersonic imaging device can carry out imaging to detection neoplastic lesion position and size.
As shown in Figure 6, be the flow chart of inner peeping type nasopharyngeal carcinoma ultrasonic imaging method in an embodiment.This inner peeping type nasopharyngeal carcinoma ultrasonic imaging method, comprising:
Step S610, initialization step, provides photographic head connected successively, video signal processing unit, control and image-generating unit, ultrasonic action and receiving element and ultrasonic transducer.
Concrete, this ultrasonic action and receiving element comprise the excitation and data processor, pulse driver, impulse sender, high-voltage switch gear, low-noise amplifier, wave filter, A/D converter that are connected successively, this excitation is connected with image-generating unit with this control with data processor, and this high-voltage switch gear is connected with this ultrasonic transducer.
Step S620, video acquisition step, by the organism optical image of this camera collection nasopharynx inner surface, digital signal is converted into through described video signal processing unit, this digital data transmission preserved to this control and image-generating unit and shows, according to this digital signal, this ultrasonic transducer being guided and location.
Step S630, produces pulse signal step, sends control instruction by this control and image-generating unit, controls this ultrasonic action and receiving element produces specific pulse signal.
In the present embodiment, produce pulse signal step to comprise: receive by this excitation and data processor the control instruction that this control and image-generating unit send, and control this pulse driver according to this control instruction and pulse generator produces specific pulse signal, and this pulse signal is transferred to this ultrasonic transducer through this high-voltage switch gear, produce ultrasound wave to encourage this ultrasonic transducer.
The frequency of this pulse signal is 10MHz (megahertz) ~ 60MHz.
Step S640, scanning step, the Endonasopharyngeal ultrasound wave of scanning is produced according to the excitation of this pulse signal by this ultrasonic transducer, and the ultrasound echo signal of this nasopharynx internal reflection is received by this ultrasonic transducer, and this ultrasound echo signal is converted into electric echo signal, and this electric echo signal is sent to this ultrasonic action and receiving element.
Step S650, revises step, processes this electric echo signal.
In the present embodiment, this correction step comprises: this electric echo signal transformed by this ultrasonic transducer is after the switching of this high-voltage switch gear, after this low-noise amplifier, wave filter, A/D converter, excitation and data processor processes, be transferred to this control and image-generating unit.
In addition, this correction step comprises: to this echo-signal carry out process comprise adopt digital filtering algorithm, time gain compensation algorithm, envelope detection algorithm, digital scan conversion algorithm, doppler frequency spectrum analysis algorithm, at least one processes in algorithm for image enhancement.
Step S660, image-forming step, carries out ultra sonic imaging according to this electric echo signal after this process.
Above-mentioned inner peeping type nasopharyngeal carcinoma ultrasonic imaging method, by camera collection organism optical image, video image is provided to be that ultrasonic transducer guides and locates, adopt ultrasonic transducer to nasopharynx inwall soft-tissue imaging, realize the full degree of depth accurately image of nasopharynx inwall soft tissue, improve the accuracy of detection.And traditional nasopharynx scope adopts optical imaging modalities, the color on nasopharynx inwall top layer, gloss and shape information can only be observed.
The above embodiment only have expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but therefore can not be interpreted as the restriction to the scope of the claims of the present invention.It should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Claims (5)
1. an inner peeping type nasopharyngeal carcinoma supersonic imaging device, is characterized in that, comprising:
Photographic head, for gathering the organism optical image of nasopharynx inner surface;
Video signal processing unit, is connected with described photographic head, is converted into digital signal for carrying out process to the organism optical image of described collection;
Control and image-generating unit, be connected with described video signal processing unit, for preserving and showing described digital signal, and send control instruction;
Ultrasonic action and receiving element, be connected with image-generating unit with described control, for receiving the control instruction that described control and image-generating unit send, and produces specific pulse signal according to described control instruction, and carry out the process of electric echo signal;
Ultrasonic transducer, be connected with receiving element with described ultrasonic action, for producing the Endonasopharyngeal ultrasound wave of scanning according to described pulse signal excitation, and receive the ultrasound echo signal of described nasopharynx inner tissue reflection, and described ultrasound echo signal is converted into electric echo signal, and described electric echo signal is sent to described ultrasonic action and receiving element;
Electric echo signal after process also for processing described electric echo signal, and is transferred to described control and image-generating unit by described ultrasonic action and receiving element; And
Described control and image-generating unit also for carrying out ultra sonic imaging according to the described electric echo signal after processing, and obtain video image according to described digital signal, guide and location described ultrasonic transducer according to described video image;
Described control and image-generating unit comprise man-machine interaction subelement, video signal Storage & Display subelement, control subelement, activation sequence generating subunit, buffer memory subelement and multiparameter ultra sonic imaging subelement, and described activation sequence generating subunit is connected with receiving element with described ultrasonic action respectively by data-interface with buffer memory subelement;
Described video signal Storage & Display subelement is for receiving the digital signal of described video signal processing unit transmission;
Described imaging control parameters for receiving the imaging control parameters of input, and is transferred to described control subelement and described activation sequence generating subunit to produce pulse train by described man-machine interaction subelement;
Described activation sequence generating subunit is used for described pulse train to send to described ultrasonic action and receiving element by data-interface;
Described buffer memory subelement is used for receiving and storing described electric echo signal, and described electric echo signal is transferred to described multiparameter ultra sonic imaging subelement;
Described multiparameter ultra sonic imaging subelement is used for carrying out multi-parameter fusion imaging according to described electric echo signal, and described multi-parameter fusion imaging is presented at described man-machine interaction subelement.
2. inner peeping type nasopharyngeal carcinoma supersonic imaging device according to claim 1, it is characterized in that, described ultrasonic action and receiving element comprise the excitation and data processor, pulse driver, impulse sender, high-voltage switch gear, low-noise amplifier, wave filter, A/D converter that are connected successively, described excitation is connected with image-generating unit with described control with data processor, and described high-voltage switch gear is connected with described ultrasonic transducer;
The control instruction that described excitation and data processor send for receiving described control and image-generating unit, and control described pulse driver according to described control instruction and pulse generator produces specific pulse signal, and described pulse signal is transferred to described ultrasonic transducer through described high-voltage switch gear, produce ultrasound wave to encourage described ultrasonic transducer;
The described electric echo signal that described ultrasonic transducer transforms, after described high-voltage switch gear switching, after described low-noise amplifier, wave filter, A/D converter, excitation and data processor processes, is transferred to described control and image-generating unit.
3. inner peeping type nasopharyngeal carcinoma supersonic imaging device according to claim 1, it is characterized in that, described ultrasonic action and receiving element carry out process to described electric echo signal and comprise and adopt at least one in digital filtering algorithm, time gain compensation algorithm, envelope detection algorithm, digital scan conversion algorithm, doppler frequency spectrum analysis algorithm, algorithm for image enhancement to process.
4. inner peeping type nasopharyngeal carcinoma supersonic imaging device according to claim 1, is characterized in that, described ultrasonic transducer comprises multiple Under Ultrasonic Vibration unit.
5. inner peeping type nasopharyngeal carcinoma supersonic imaging device according to claim 1, is characterized in that, the frequency of described specific pulse signal is 10MHz ~ 60MHz.
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| CN201310330411.2A CN103385736B (en) | 2013-07-31 | 2013-07-31 | Inner peeping type nasopharyngeal carcinoma supersonic imaging device |
| PCT/CN2013/081350 WO2015013995A1 (en) | 2013-07-31 | 2013-08-13 | Endoscopic ultrasonic imaging device and method for nasopharynx cancer |
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| CN106846458A (en) * | 2016-12-15 | 2017-06-13 | 哈尔滨工业大学（威海） | Stereoscopic ultrasonic model building method and device based on 3D printing |
| CN110891507B (en) | 2017-04-28 | 2023-06-23 | 阿里内克斯股份有限公司 | Systems and methods for locating blood vessels in the treatment of rhinitis |
| CN108542422A (en) * | 2018-03-06 | 2018-09-18 | 武汉轻工大学 | B ultrasound image optimization method, device and computer readable storage medium |
| CN109691984A (en) * | 2018-12-07 | 2019-04-30 | 深圳先进技术研究院 | A kind of multi-mode imaging system of pancreatic duct |
| WO2022120836A1 (en) * | 2020-12-11 | 2022-06-16 | 深圳先进技术研究院 | Irreversible sonoporation device and apparatus, and computer readable storage medium |
| CN115633926A (en) * | 2022-12-23 | 2023-01-24 | 山东百多安医疗器械股份有限公司 | Multi-mode ultrasonic electrocardio endoscope diagnosis and treatment instrument |
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| CN103385736A (en) | 2013-11-13 |
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