CN106846458A - Stereoscopic ultrasonic model building method and device based on 3D printing - Google Patents
Stereoscopic ultrasonic model building method and device based on 3D printing Download PDFInfo
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Abstract
The present invention relates to a kind of stereoscopic ultrasonic model building method and device based on 3D printing, including：Two-dimensional scan is carried out to tissue surface to be measured using ultrasonic probe, in transmitting ultrasonic wave to the test serum, and the ultrasound echo signal of reflection is received；The ultrasound echo signal is pre-processed；According to pretreated ultrasound echo signal, the internal structure parameter of each scan position point in the test serum is determined；According to the internal structure parameter of each scan position point in the test serum and corresponding scan position point, the three-dimensional model of the test serum is built, and by three-dimensional model described in 3D printing system print.Technical scheme provided in an embodiment of the present invention, can be used for medical industry, for carrying out external model manufacture to human organ etc., be convenient for in-vitro simulated treatment, form, lesion of significantly more efficient observation human organ etc., improve the validity and security for the treatment of.
Description
Technical field
The present invention relates to medical ultrasound technical field, more particularly to a kind of ultrasonic vertical body Model structure based on 3D printing
Construction method and device.
Background technology
Tumour is body under the effect of various tumorigenesis factors, and the cell of local organization loses on gene level and it is grown
Normal regulation cause paraplasm with differentiation and formed neoformation.The growth of malignant tumour can destroy normal tissue and device
, easily there is bleeding, necrosis, ulcer etc. in official, and its fast growth, cause human body to become thin, powerless, anaemia, poor appetite, hair
Hot and serious organ function is impaired etc., ultimately causes death, be human health is threatened at present maximum disease it
One.If can cross that accurate tumor model is set up, more efficiently will accurately realize the diagnosis of tumour, this diagnosis to tumour and
Treatment is significant.
In medical domain, the length of three-dimensional quantitative measurement organ or wound, angle, area or volume are for accurately
It is considerable to solve anatomical structure, the physiological behavior of research organ or tissue and then provide Accurate Diagnosis conclusion.Generally
Accurate three-dimensional measurement only can be by the volume diagram that is obtained according to shadow (CT) by magnetic resonance imaging (MRI) and X ray computer tomography
As realizing.
The three-dimensional measurement inspection that MRI or CT technologies are carried out diagnoses somewhat expensive, data processing and also takes very much.Additionally,
When carrying out X-ray CT scan, person under inspection must not be not subject to harmful radiation.From unlike CT and MRI, using ultrasonic imaging
Technology has the advantages that cheap, non-radiation type, non-damage and easily operated.But traditional two-dimentional B ultrasonic ultra sonic scanner
System, operator mobile probe and produces two-dimentional anatomical cross-sectional view below probe above the skin of person under inspection in real time
Picture.The method can carry out quickly tissue measurement.But, limited by two dimensional image signal, subsequent graphical analysis only office
It is limited to single two dimensional surface.
The content of the invention
The technical problems to be solved by the invention are to provide a kind of stereoscopic ultrasonic model building method based on 3D printing
And device.
For this purpose, the present invention proposes a kind of stereoscopic ultrasonic model building method based on 3D printing, including：
Two-dimensional scan is carried out to tissue surface to be measured using ultrasonic probe, in transmitting ultrasonic wave to the test serum, and
Receive the ultrasound echo signal of reflection；
The ultrasound echo signal is pre-processed；
According to pretreated ultrasound echo signal, the internal structure of each scan position point in the test serum is determined
Parameter；
According to the internal structure parameter of each scan position point in the test serum and corresponding scan position point, build
The three-dimensional model of the test serum, and by three-dimensional model described in 3D printing system print.
Preferably, it is described that ultrasound echo signal is pre-processed, including：
Time gain compensation enhanced processing is carried out to the ultrasound echo signal；
Ultrasound echo signal after enhanced processing is carried out into pre-filtering treatment；
Data signal will be converted to by the ultrasound echo signal of pre-filtering, obtains digital echo signal.
Preferably, it is described that ultrasound echo signal is pre-processed, also include：
The digital echo signal is stored.
Preferably, according to pretreated ultrasound echo signal, each scan position point in the test serum is determined
Internal structure parameter, specifically includes：
The launch time of the ultrasonic wave according to each scan position point, the reception time of the ultrasound echo signal with
And the amplitude of the ultrasound echo signal, the ultrasonic propagation velocity of the test serum of each scan position point is calculated, really
Determine thickness, density and the acoustic impedance of the test serum of each scan position point.
Preferably, it is described according to the internal structure parameter of each scan position point and corresponding scanning in the test serum
Location point, builds the three-dimensional model of the test serum, including
The thickness of the test serum according to each scan position point, density and acoustic impedance obtain continuous two-dimensional ultrasound
Image；
The continuous two-dimensional ultrasonic image is carried out into three-dimensionalreconstruction, the three-dimensional model of the test serum is formed.
On the other hand, the embodiment of the present invention additionally provides a kind of stereoscopic ultrasonic model construction device based on 3D printing,
The device includes：
Ultrasonic probe, data preprocessing module, data processing module and the 3D printing system being sequentially connected；
The ultrasonic probe is used to carry out tissue surface to be measured two-dimensional scan, transmitting ultrasonic wave to the test serum
On, and receive the ultrasound echo signal of reflection；
The data preprocessing module is used to pre-process the ultrasound echo signal；
The data processing module is used for according to pretreated ultrasound echo signal, determines in the test serum each
The internal structure parameter of scan position point；According to the internal structure parameter and correspondence of each scan position point in the test serum
Scan position point, build the three-dimensional model of the test serum；
The 3D printing system is used to print the three-dimensional model.
Preferably, the data preprocessing module includes：The main control unit being connected with the ultrasonic probe, is sequentially connected
Time gain compensation amplifying unit, pre-filtering unit, A/D converting units；The main control unit connects the time gain compensation
Amplifying unit；
The main control unit is used to send scan control signal to the ultrasonic probe, and receives the ultrasonic probe return
Ultrasound echo signal；
The time gain compensation amplifying unit is used to carry out at time gain compensation amplification the ultrasound echo signal
Reason；
The pre-filtering unit is used to for the ultrasound echo signal after enhanced processing to carry out pre-filtering treatment；
The A/D converting units are used to that data signal will to be converted to by the ultrasound echo signal of pre-filtering, obtain
Digital echo signal.
Preferably, the data preprocessing module also includes：The data buffer storage unit that is connected with the A/D converting units,
The interface transmission unit being connected with the data buffer storage unit；
The data buffer storage unit is used to store the digital echo signal；
The interface transmission unit is used to transmit the digital echo signal that the data buffer storage unit is stored to the number
According to processing module.
Preferably, the device also includes：The stepper motor being connected with the main control unit；The stepper motor is used in institute
State under the control of main control unit, drive the ultrasonic probe to be moved in two-dimensional scanning platform.
Preferably, the data processing module specifically for：
The launch time of the ultrasonic wave according to each scan position point, the reception time of the ultrasound echo signal with
And the amplitude of the ultrasound echo signal, the ultrasonic propagation velocity of the test serum of each scan position point is calculated, really
Determine thickness, density and the acoustic impedance of the test serum of each scan position point；
The thickness of the test serum according to each scan position point, density and acoustic impedance obtain continuous two-dimensional ultrasound
Image；
The continuous two-dimensional ultrasonic image is carried out into three-dimensionalreconstruction, the three-dimensional model of the test serum is formed.
A kind of stereoscopic ultrasonic model building method and device based on 3D printing provided in an embodiment of the present invention, by super
Sonic probe is scanned to test serum, and the structural parameters for obtaining test serum build three-dimensional model, and by 3D printing technique
Virtual three-dimensional model is become the three-dimensional model of entity, technical scheme provided in an embodiment of the present invention can be used for medical row
Industry, for carrying out external model manufacture to human organ etc., is convenient for in-vitro simulated treatment, significantly more efficient observation human body device
Form, lesion of official etc., improve the validity and security for the treatment of.
Brief description of the drawings
The features and advantages of the present invention can be more clearly understood from by reference to accompanying drawing, accompanying drawing is schematical without that should manage
Solution is to carry out any limitation to the present invention, in the accompanying drawings：
Fig. 1 is that the flow of the stereoscopic ultrasonic model building method based on 3D printing provided in an embodiment of the present invention is illustrated
Figure；
The step of stereoscopic ultrasonic model building method based on 3D printing that Fig. 2 is provided for another embodiment of the present invention S2
Idiographic flow schematic diagram；
The step of stereoscopic ultrasonic model building method based on 3D printing that Fig. 3 is provided for further embodiment of this invention S2
Idiographic flow schematic diagram；
Fig. 4 is that the framework of the stereoscopic ultrasonic model construction device based on 3D printing provided in an embodiment of the present invention is illustrated
Figure；
Fig. 5 is the structural representation of the stereoscopic ultrasonic model construction device based on 3D printing provided in an embodiment of the present invention
Figure.
Specific embodiment
Below in conjunction with accompanying drawing, embodiments of the present invention is described in detail.
3D printing technique is an emerging technology, and it is provided, and one kind is simple, quick, flexibility is good, high-precision 3D
Model structure construction method, plays a significant role in the evolution of virtual test, generally uses digital technology material
Printer is often used for modeling come what is realized in fields such as Making mold, industrial designs, after be gradually available for some products
Directly manufacture.At present, 3D printing technique can be widely applied to many aspects such as medical treatment, wherein entering with 3D printing technique
Treatment data mapping of practising medicine is a very promising direction.But, the virtual image based on 3D printing technique is not advised greatly also
Mould is applied to reality.
The velocity of wave of test serum, acoustic impedance, decay, backscattering coefficient and non-can be gone out with quantitative analysis using ultrasonic imaging
The parameter such as linear, can construct with reference to 3D printing technique and accurately organize model, help to be finely adjusted dosage, or even
The situation that different patients can be directed to is customized personal therapeutic scheme, and 3D printing technique can bring new think of for treatment
Road, i.e., external modeling, and can be filled with liquid, allow doctor more preferably to observe medicament mobility status in more detail, contribute to
Assess suitable dosage, doctor's more effectively treating cancer can be helped, additionally can by 3D cell printing technologies,
The biological tissue of cancer is directly printed in vitro, so can more effectively be observed by vitro culture cancer tissue
Tumor tissues, it might even be possible to carry out in-vitro simulated treatment, in case carrying out treating caused adverse consequences by patient body rashly.
As shown in figure 1, a kind of stereoscopic ultrasonic model building method based on 3D printing is the embodiment of the invention provides, should
Method is comprised the following steps：
S1：Two-dimensional scan is carried out to tissue surface to be measured using ultrasonic probe, in transmitting ultrasonic wave to the test serum,
And receive the ultrasound echo signal of reflection；
Wherein, ultrasonic probe uses centre frequency to be popped one's head in for the broad band ultrasonic of 25MHz, with 128 array elements, specifically,
The array element face of ultrasonic probe is placed in the initial position of two-dimensional scanning platform perpendicular to test serum surface, so that test serum
One end starts scanning, on transmitting ultrasonic wave to test serum, produces ultrasonic signal, the reflection of ultrasonic probe simultaneous observation test serum
The ultrasound echo signal returned, the ultrasound echo signal that will be collected is carried out by after pretreatment, uploading to data processing module
Follow-up data treatment.Behind a scanned position, ultrasonic probe is driven under reaching in two-dimensional scanning platform by stepper motor
One scan position proceeds scanning, it then follows from left to right scanning sequency from top to bottom, successively by different scanning position
Ultrasound echo signal and corresponding scan position data is activation carry out data processing to data processing module.Wherein it is possible to
Driving stepper motor ultrasonic probe is controlled to move to next position from a position by main control unit.As needed, it is to be measured
Tissue can be tissue, organ etc..
S2：The ultrasound echo signal is pre-processed；
It should be noted that because ultrasound echo signal can be decayed in communication process, it is possible to which ultrasound is returned
Ripple signal carries out time gain compensation amplification, and pre-filtering treatment etc. is carried out as needed.
S3：According to pretreated ultrasound echo signal, the inside of each scan position point in the test serum is determined
Structural parameters；
Specifically, data processing can be carried out to ultrasound echo signal by data processing module, according to ultrasonic probe
Signal time of return, amplitude, can calculate the ultrasonic propagation velocity of the test serum of correspondence scan position, be passed according to ultrasonic wave
Broadcast speed and signal time of return can calculate correspondence position test serum thickness, density, may thereby determine that correspondence is swept
The acoustic impedance of the test serum of position is retouched, it is necessary to illustrate, acoustic impedance can reflect the internal structure of test serum.In order that
The model more standard of the follow-up test serum set up, can with the internal structure parameter of test serum can also include phase velocity,
Acoustic attenuation.
S4：According to the internal structure parameter of each scan position point in the test serum and corresponding scan position point,
The three-dimensional model of the test serum is built, and by three-dimensional model described in 3D printing system print.
Specifically, can according to the ultrasound echo signal of different scanning position acquisition, be calculated acoustic impedance, phase velocity and
Acoustic attenuation, so that the two-dimensional ultrasonic image for forming the test serum of different scanning position (specifically may refer to the B ultrasonic of prior art
Image-forming principle), two-dimensional ultrasonic image is carried out by three-dimensionalreconstruction using the DirectX programs write based on Visual C# languages, then
The three-dimensional model of test serum can be obtained, the three-dimensional model is printed by 3D printing system, can be obtained accurately
Tissue model, helps to be finely adjusted dosage, and for treatment brings new thinking, i.e., external modeling can help cure
The diseases such as raw more effectively treatment tumour, additionally directly can in vitro print cancer by 3D cell printing technologies
Biological tissue, carries out in-vitro simulated treatment, improves the validity and security for the treatment of.
A kind of stereoscopic ultrasonic model building method based on 3D printing provided in an embodiment of the present invention, by ultrasonic probe
Test serum is scanned, the structural parameters for obtaining test serum build three-dimensional model, and will be virtual by 3D printing technique
Three-dimensional model become the three-dimensional model of entity, technical scheme provided in an embodiment of the present invention can be used for medical industry, be used for
External model manufacture is carried out to human organ etc., in-vitro simulated treatment, the shape of significantly more efficient observation human organ is convenient for
State, lesion etc., improve the validity and security for the treatment of.
On the basis of above-described embodiment, as shown in Fig. 2 being pre-processed to ultrasound echo signal described in step S2, wrap
Include：
S21：Time gain compensation enhanced processing is carried out to the ultrasound echo signal；
S22：Ultrasound echo signal after enhanced processing is carried out into pre-filtering treatment；
S23：Data signal will be converted to by the ultrasound echo signal of pre-filtering, obtains digital echo signal.
Further, as shown in figure 3, step S2 is pre-processed to ultrasound echo signal, can also include：
S24：The digital echo signal is stored.
Specifically, TGC (time gain compensation) amplifying circuit can be followed by ultrasonic probe, pre-flock wave circuit and A/D turn
Circuit and ARM data caching circuits are changed, TGC amplifying circuits put the ultrasound echo signal that ultrasonic probe is received by TGC
Big device is compensated and amplifies the echo-signal gradually decayed with propagation distance increase, and the variable gain of TGC amplifiers is with the time
Exponentially increase, the ultrasound echo signal after enhanced processing is carried out pre-filtering by pre-flock wave circuit, in filtering analog signal
High frequency spurs, the ultrasound echo signal after pre-filtering is converted to digital echo signal by A/D change-over circuits, optionally, can be with
The storage of digital echo signal is carried out by ARM data caching circuits, and is passed digital echo signal by USB data transmission circuit
Transporting to data processing equipment carries out follow-up data processing.
Wherein, TGC amplifying circuits, A/D change-over circuits, ARM data caching circuits and USB data transmission circuit can be with
Connection main control unit, main control unit connection ultrasonic probe, the ultrasound echo signal that ultrasonic probe is received can be passed by main control unit
TGC amplifying circuits are transported to, pre-filtering is carried out by being transferred to pre-flock wave circuit after the amplification of TGC amplifying circuits, then electricity is changed by A/D
Road is converted to digital echo signal, and after being cached by ARM data caching circuits, is returned numeral by USB data transmission circuit
Ripple signal transmission to data processing equipment carries out follow-up data processing.Wherein, ARM data caching circuits include multi-channel parallel
Data caching circuit, port number is 128, i.e., port number is corresponded with the array element of ultrasonic probe.
On the basis of above-described embodiment, step S3 determines described to be measured group according to pretreated ultrasound echo signal
The internal structure parameter of each scan position point is knitted, is specifically included：
The launch time of the ultrasonic wave according to each scan position point, the reception time of the ultrasound echo signal with
And the amplitude of the ultrasound echo signal, the ultrasonic propagation velocity of the test serum of each scan position point is calculated, really
Determine thickness, density and the acoustic impedance of the test serum of each scan position point.
Specifically, assuming dsThe thickness of test serum is represented,Each ultrasonic signal is represented, the wherein value of i is by arteries and veins
Number decision is rushed, c represents spread speed of the ultrasonic wave in couplant.
vs=c (Δ t/2 τ+1)
ds=(vsΔt)/2
Wherein, vsThe speed of propagation of the ultrasonic wave in test serum, 2 τ be ultrasonic wave from test serum upper surface to
The reflection interval of reflecting interface is poor, and Δ t is the time difference of ultrasonic wave arrival reflecting interface before and after placement test serum.
The information of phase velocity and acoustic attenuation is extracted using spectral method, acoustic attenuation and phase velocity can be by equations of transferObtain, whereinIt is signalFast Fourier Transform (FFT),It is signalFast Fourier Transform (FFT).
The phase velocity of test serum：WhereinIt is corresponding expansion
Phase.a0It is initial phase coefficient, f is ultrasonic frequency.
The acoustic attenuation of test serum：Wherein Dj/ i=
Dγ (i)/Dγ (j), DγFor representing diffraction correction, for avoiding due to the diffraction effect that ultrasonic probe dimensional problem is brought.T is to work as
Acoustic signals pass through overall transmission coefficient during organizational interface, parameter alphawIt is the sound in the couplant tried to achieve using 7 rank multinomials
Decay.
Test serum densityWherein E is Young's modulus, and σ is Poisson's ratio.
The acoustic impedance of test serum：Z=ρ × vs。
On the basis of above-described embodiment, according to the inside of each scan position point in the test serum described in step S4
Structural parameters and corresponding scan position point, build the three-dimensional model of the test serum, including
The thickness of the test serum according to each scan position point, density and acoustic impedance obtain continuous two-dimensional ultrasound
Image；
The continuous two-dimensional ultrasonic image is carried out into three-dimensionalreconstruction, the three-dimensional model of the test serum is formed.
It should be noted that ultrasonic probe is in test serum surface scan, behind a scanned position, ultrasonic probe exists
Driven by stepper motor in two-dimensional scanning platform and reach next scan position and proceed scanning, it then follows from left to right on to
Under scanning sequency, the ultrasound echo signal of whole test serum surface diverse location can be obtained, according to the super of each position
Sound echo-signal can calculate the information such as thickness, density, the acoustic impedance of test serum, so as to be obtained according to these information
The two-dimensional ultrasonic image of each position.The two-dimensional ultrasonic image of each position is carried out into fusion reconstruct, it is possible to obtain to be measured group
The three-dimensional model knitted.
On the other hand, as shown in figure 4, the embodiment of the present invention additionally provides a kind of ultrasonic vertical body Model based on 3D printing
Construction device, the device can be using the stereoscopic ultrasonic model building method based on 3D printing described in above-described embodiment, should
Device includes：
Ultrasonic probe 1, data preprocessing module 2, data processing module 3 and the 3D printing system 4 being sequentially connected；
The ultrasonic probe 1 is used to carry out the surface of test serum 7 two-dimensional scan, transmitting ultrasonic wave to the test serum
On 7, and receive the ultrasound echo signal of reflection；
The data preprocessing module 2 is used to pre-process the ultrasound echo signal；
The data processing module 3 is used for according to pretreated ultrasound echo signal, determines each in the test serum 7
The internal structure parameter of individual scan position point；According to the internal structure parameter of each scan position point in the test serum 7 and
Corresponding scan position point, builds the three-dimensional model of the test serum 7；
The 3D printing system 4 is used to print the three-dimensional model.
A kind of stereoscopic ultrasonic model construction device based on 3D printing provided in an embodiment of the present invention, by ultrasonic probe
Test serum is scanned, the structural parameters for obtaining test serum build three-dimensional model, and will be virtual by 3D printing technique
Three-dimensional model become the three-dimensional model of entity, technical scheme provided in an embodiment of the present invention can be used for medical industry, be used for
External model manufacture is carried out to human organ etc., in-vitro simulated treatment, the shape of significantly more efficient observation human organ is convenient for
State, lesion etc., improve the validity and security for the treatment of.
On the basis of above-described embodiment, the data preprocessing module 2 includes the master control being connected with the ultrasonic probe 1
Unit 21, the time gain compensation amplifying unit 22 being sequentially connected, pre-filtering unit 23, A/D converting units 24；The master control list
The connection of the unit 21 time gain compensation amplifying unit 22；
The main control unit 21 is used to send scan control signal to the ultrasonic probe 1, and receives the ultrasonic probe 1
The ultrasound echo signal of return；
The time gain compensation amplifying unit 22 is used to carry out time gain compensation amplification to the ultrasound echo signal
Treatment；
The pre-filtering unit 23 is used to for the ultrasound echo signal after enhanced processing to carry out pre-filtering treatment；
The A/D converting units 24 are used to that data signal will to be converted to by the ultrasound echo signal of pre-filtering, obtain
To digital echo signal.
Further, the data preprocessing module 2 also includes：The data buffer storage being connected with the A/D converting units 24
Unit 25 and the interface transmission unit 26 of the connection of the data buffer storage unit 25；
The data buffer storage unit 25 is used to store the digital echo signal；
The interface transmission unit 26 is used to transmit the digital echo signal that the data buffer storage unit 25 is stored to institute
State data processing module 3.
It should be noted that the time gain compensation amplifying unit 22 can be the time gain in above method embodiment
Amplifying circuit, the pre-filtering unit 23 can be able to be for the pre-flock wave circuit in above method embodiment, A/D converting units 24
A/D change-over circuits in above method embodiment, data buffer storage unit 25 can be above method embodiment in based on ARM numbers
According to buffer circuit, interface transmission unit 26 can be the USB data transmission circuit in above method embodiment.
On the basis of above-described embodiment, optionally, the stereoscopic ultrasonic model construction device based on 3D printing is also
Including：The stepper motor 6 being connected with the main control unit 21；The stepper motor 6 is used for the control in the main control unit 21
Under, drive the ultrasonic probe 1 to be moved in two-dimensional scanning platform 5.
On the basis of above-described embodiment, optionally, the data processing module 3 specifically for：
The launch time of the ultrasonic wave according to each scan position point, the reception time of the ultrasound echo signal with
And the amplitude of the ultrasound echo signal, the ultrasonic propagation velocity of the test serum 7 of each scan position point is calculated, really
Determine thickness, density and the acoustic impedance of the test serum 7 of each scan position point；
It is super that the thickness of the test serum 7 according to each scan position point, density and acoustic impedance obtain continuous two dimension
Acoustic image；
The continuous two-dimensional ultrasonic image is carried out into three-dimensionalreconstruction, the three-dimensional model of the test serum 7 is formed.
For the stereoscopic ultrasonic model construction device embodiment based on 3D printing corresponding with method, due to its with
Embodiment of the method is substantially similar, can carry out model construction using the step of using embodiment of the method, the technique effect for reaching
Identical with the effect that embodiment of the method is played, so description is fairly simple, related part is said referring to the part of embodiment of the method
It is bright.
Although being described in conjunction with the accompanying embodiments of the present invention, those skilled in the art can not depart from this hair
Various modifications and variations are made in the case of bright spirit and scope, such modification and modification are each fallen within by appended claims
Within limited range.
Claims (10)
1. a kind of stereoscopic ultrasonic model building method based on 3D printing, it is characterised in that including：
Two-dimensional scan is carried out to tissue surface to be measured using ultrasonic probe, in transmitting ultrasonic wave to the test serum, and is received
The ultrasound echo signal of reflection；
The ultrasound echo signal is pre-processed；
According to pretreated ultrasound echo signal, the internal structure ginseng of each scan position point in the test serum is determined
Number；
According to the internal structure parameter of each scan position point in the test serum and corresponding scan position point, build described
The three-dimensional model of test serum, and by three-dimensional model described in 3D printing system print.
2. method according to claim 1, it is characterised in that described to be pre-processed to ultrasound echo signal, including：
Time gain compensation enhanced processing is carried out to the ultrasound echo signal；
Ultrasound echo signal after enhanced processing is carried out into pre-filtering treatment；
Data signal will be converted to by the ultrasound echo signal of pre-filtering, obtains digital echo signal.
3. method according to claim 2, it is characterised in that described to be pre-processed to ultrasound echo signal, also includes：
The digital echo signal is stored.
4. method according to claim 1, it is characterised in that according to pretreated ultrasound echo signal, it is determined that described
The internal structure parameter of each scan position point, specifically includes in test serum：
The launch time of the ultrasonic wave according to each scan position point, the reception time of the ultrasound echo signal and institute
The amplitude of ultrasound echo signal is stated, the ultrasonic propagation velocity of the test serum of each scan position point is calculated, it is determined that respectively
The thickness of the test serum of individual scan position point, density and acoustic impedance.
5. method according to claim 4, it is characterised in that described according to each scan position point in the test serum
Internal structure parameter and corresponding scan position point, build the three-dimensional model of the test serum, including
The thickness of the test serum according to each scan position point, density and acoustic impedance obtain continuous two-dimensional ultrasound figure
Picture；
The continuous two-dimensional ultrasonic image is carried out into three-dimensionalreconstruction, the three-dimensional model of the test serum is formed.
6. a kind of stereoscopic ultrasonic model construction device based on 3D printing, it is characterised in that including：
Ultrasonic probe, data preprocessing module, data processing module and the 3D printing system being sequentially connected；
The ultrasonic probe is used to carry out tissue surface to be measured two-dimensional scan, in transmitting ultrasonic wave to the test serum, and
Receive the ultrasound echo signal of reflection；
The data preprocessing module is used to pre-process the ultrasound echo signal；
The data processing module is used for according to pretreated ultrasound echo signal, determines each scanning in the test serum
The internal structure parameter of location point；According to the internal structure parameter of each scan position point in the test serum and corresponding sweep
Location point is retouched, the three-dimensional model of the test serum is built；
The 3D printing system is used to print the three-dimensional model.
7. device according to claim 6, it is characterised in that the data preprocessing module includes：Visited with the ultrasound
The main control unit of head connection, the time gain compensation amplifying unit being sequentially connected, pre-filtering unit, A/D converting units；The master
Control unit connects the time gain compensation amplifying unit；
The main control unit is used to send scan control signal to the ultrasonic probe, and receives the super of the ultrasonic probe return
Sound echo-signal；
The time gain compensation amplifying unit is used to carry out time gain compensation enhanced processing to the ultrasound echo signal；
The pre-filtering unit is used to for the ultrasound echo signal after enhanced processing to carry out pre-filtering treatment；
The A/D converting units are used to that data signal will to be converted to by the ultrasound echo signal of pre-filtering, obtain numeral
Echo-signal.
8. device according to claim 7, it is characterised in that also include：The data being connected with the A/D converting units are delayed
Memory cell and the interface transmission unit of data buffer storage unit connection；
The data buffer storage unit is used to store the digital echo signal；
The interface transmission unit is used to transmit the digital echo signal that the data buffer storage unit is stored to the data
Reason module.
9. device according to claim 7, it is characterised in that also include：The stepper motor being connected with the main control unit；
The stepper motor is used under the control of the main control unit, drives the ultrasonic probe to be moved in two-dimensional scanning platform.
10. device according to claim 7, it is characterised in that the data processing module specifically for：
The launch time of the ultrasonic wave according to each scan position point, the reception time of the ultrasound echo signal and institute
The amplitude of ultrasound echo signal is stated, the ultrasonic propagation velocity of the test serum of each scan position point is calculated, it is determined that respectively
The thickness of the test serum of individual scan position point, density and acoustic impedance；
The thickness of the test serum according to each scan position point, density and acoustic impedance obtain continuous two-dimensional ultrasound figure
Picture；
The continuous two-dimensional ultrasonic image is carried out into three-dimensionalreconstruction, the three-dimensional model of the test serum is formed.
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Cited By (6)
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| CN107769743A (en) * | 2017-11-23 | 2018-03-06 | 日照朝力信息科技有限公司 | A kind of ultrasonic imaging echo gain compensation circuit |
| CN108888398A (en) * | 2018-07-18 | 2018-11-27 | 无锡市中医医院 | A kind of medical distal radius anatomical form bracket clamping plate and preparation method thereof |
| CN110441397A (en) * | 2018-05-02 | 2019-11-12 | 奥林巴斯株式会社 | The method for making of apparatus for ultrasonic examination, 3D printer device and inference pattern |
| CN112684456A (en) * | 2020-12-22 | 2021-04-20 | 安徽配隆天环保科技有限公司 | Unmanned aerial vehicle supersound solid imaging model system |
| CN113631953A (en) * | 2019-03-20 | 2021-11-09 | 美国西门子医疗系统股份有限公司 | Quantitative ultrasound using fundamental and harmonic signals |
| CN117451857B (en) * | 2023-12-21 | 2024-03-08 | 新锦盛源(广东)能源科技有限公司 | Shale gas reservoir space detection method and related equipment thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107769743A (en) * | 2017-11-23 | 2018-03-06 | 日照朝力信息科技有限公司 | A kind of ultrasonic imaging echo gain compensation circuit |
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| CN112684456A (en) * | 2020-12-22 | 2021-04-20 | 安徽配隆天环保科技有限公司 | Unmanned aerial vehicle supersound solid imaging model system |
| CN112684456B (en) * | 2020-12-22 | 2024-05-17 | 安徽配隆天环保科技有限公司 | Unmanned aerial vehicle ultrasonic three-dimensional imaging model system |
| CN117451857B (en) * | 2023-12-21 | 2024-03-08 | 新锦盛源(广东)能源科技有限公司 | Shale gas reservoir space detection method and related equipment thereof |
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