CN103385736A - Endoscopic ultrasonic imaging device and method for nasopharynx cancer - Google Patents
Endoscopic ultrasonic imaging device and method for nasopharynx cancer Download PDFInfo
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Abstract
The invention relates to an endoscopic ultrasonic imaging device and an endoscopic ultrasonic imaging method for nasopharynx cancer. The device comprises a camera, a video signal processing unit, a control and imaging unit, an ultrasonic excitation and receiving unit and an ultrasonic transducer, wherein the camera is used for acquiring an optical tissue image on the inner surface of a nasopharynx; the video signal processing unit is used for converting an optical tissue image signal into a video digital signal; the control and imaging unit is used for storing and displaying the digital signal and sending a control instruction; the ultrasonic excitation and receiving unit is used for generating a specific pulse signal according to an ultrasonic control instruction for ultrasonic excitation, processing an ultrasonic echo signal and then performing ultrasonic image display; the ultrasonic transducer is used for generating an ultrasonic wave for scanning the interior of the nasopharynx according to the pulse signal, receiving the ultrasonic echo signal and converting the ultrasonic echo signal into an electric echo signal; the ultrasonic excitation and receiving unit is also used for processing the electric echo signal; the control and imaging unit is also used for performing ultrasonic imaging according to the processed electric echo signal. The detection accuracy is improved.
Description
Technical field
The present invention relates to medical apparatus and instruments, particularly relate to a kind of inner peeping type nasopharyngeal carcinoma supersonic imaging device and method.
Background technology
Nasopharyngeal carcinoma is the malignant tumor that is primary in the nasopharynx position.The annual new Nasopharyngeal Carcinoma Patients in the whole world approximately 600,000, occupy the 5th of Cancer Mortality.The nasopharyngeal carcinoma early symptom is not obvious, and the middle and advanced stage symptom comprises blood tears, bloody sputum, tinnitus, deafness, the enlargement of cervical region lymph, headache, facial numbness, diplopia, blepharoptosis, blind, dysphagia, hoarseness, deflection etc. lolls.Most symptoms can not cause that the patient suffering experiences, and the symptom of easy and other causes of disease is obscured; Usually, nasopharyngeal carcinoma is apt to occur in the mucosa of nasopharynx inwall, and this position is more hidden, and conventional indirect nasopharyngeal mirror is difficult to accurately distinguish cancerous issue.Therefore very easily out in the cold or mistaken diagnosis at the beginning of the nasopharyngeal carcinoma morbidity.Because the vital tissue organs such as nasopharynx and brain, intracranial vessel, lymph node, nerve are close, originate from the cancer in situ of mucous membrane of nasopharynx, be easy to invade the vital tissue organs such as brain, even by lymphatic vessel, blood vessel, transfer to liver, lung and bone at a distance.This is the major reason that causes NPC mortality higher.Early find that early treatment is the Key Principles of preventing and treating nasopharyngeal carcinoma.
According to the pathological characteristics of tumor cell, nasopharyngeal carcinoma can be divided into cancer in situ, micro-infiltrating carcinoma, squamous cell carcinoma, adenocarcinoma, vesicular nucleus cell carcinoma and undifferentiated carcinoma.Different according to the profile of nasopharyngeal carcinoma, can be divided into nodular type, fungating type, infiltrative type, ulcer type and mucosa mo(u)ld bottom half.For the tumor invading scope being done unified assessment, the normal TNM standard that adopts is (namely according to the degree of other histoorgans of comprehensive assessment tumor invading, the degree of the contiguous lymph node of tumor invading, neoplasm metastasis is to the scope at other positions), tumor is divided into I, II, III, IV a, five phases of IV b.TNM by stages more after, represent that tumor invading, metastasis degree are higher, patient's treatment survival rate is lower.Because nasopharyngeal carcinoma cell is very responsive to high-energy ray, so radiotherapy is the Main Means for the treatment of nasopharyngeal carcinoma.Before implementing radiotherapy, need to adopt the image means such as CT, MRI accurately to locate range of tumor, to determine position and the dosage of x radiation x.
Yet, the CT imaging technique, density resolution is high, is fit to bone or calcified tissue's imaging, and imaging is its weakness for human body soft tissue.Canceration or Fibrotic mucous membrane of nasopharynx tissue, though can be identified roughly in the CT imaging, the tissue variation of trickle (as diameter less than 1 millimeter), but be difficult to by reliable recognition.MRI technology, properties all are better than the CT imaging technique, but its diagnosis somewhat expensive, taboo are used for patient that health is implanted into metal or magnetic material, to the insensitive deficiency that waits of tissue variation of trickle (as diameter less than 1 millimeter).
Summary of the invention
Based on this, be necessary to detect coarse problem for the device that at present nasopharynx is detected, a kind of inner peeping type nasopharyngeal carcinoma supersonic imaging device that can improve accuracy in detection is provided.
In addition, also be necessary to provide a kind of inner peeping type nasopharyngeal carcinoma ultrasonic imaging method that can improve accuracy in detection.
A kind of inner peeping type nasopharyngeal carcinoma supersonic imaging device comprises:
Photographic head, for the organism optical image that gathers the nasopharynx inner surface;
Video signal processing unit, be connected with described photographic head, is used for the organism optical image of described collection is processed and is converted into digital signal;
Control and image-generating unit, with described video signal processing unit, be connected, be used for preserving and showing described digital signal, and send control instruction;
Ultrasonic action and receiving element, be connected with image-generating unit with described control, is used for receiving the control instruction of described control and image-generating unit transmission, and according to described control instruction, produces specific pulse signal;
Ultrasonic transducer, be connected with receiving element with described ultrasonic action, be used for producing the Endonasopharyngeal ultrasound wave of scanning according to described pulse signal excitation, and receive the ultrasound echo signal of described nasopharynx internal reflection, and described ultrasound echo signal is converted into the echo signal of telecommunication, and the described echo signal of telecommunication is sent to described ultrasonic action and receiving element;
Described ultrasonic action and receiving element also are used for the described echo signal of telecommunication is processed, and the echo electric signal transmission after processing is given described control and image-generating unit; And
Described control and image-generating unit also are used for carrying out ultra sonic imaging according to the described echo signal of telecommunication after processing, and according to described digital signal, obtain video image, according to described video image, described ultrasonic transducer are guided and locate.
Therein in embodiment, described ultrasonic action and receiving element comprise the excitation that is connected successively and data processor, pulse driver, impulse sender, high-voltage switch gear, low-noise amplifier, wave filter, A/D converter, described excitation is connected with image-generating unit with described control with data processor, and described high-voltage switch gear is connected with described ultrasonic transducer;
Described excitation and data processor are used for receiving the control instruction of described control and image-generating unit transmission, and according to described control instruction, control described pulse driver and the specific pulse signal of pulse generator generation, and described pulse signal is transferred to described ultrasonic transducer through described high-voltage switch gear, to encourage described ultrasonic transducer generating ultrasound wave;
The described echo signal of telecommunication that described ultrasonic transducer transforms after described high-voltage switch gear switching, after described low-noise amplifier, wave filter, A/D converter, excitation and data processor processes, is transferred to described control and image-generating unit.
Therein in embodiment, described ultrasonic action and receiving element are processed and are comprised and adopt at least a processing the in digital filtering algorithm, time gain compensation algorithm, envelope detection algorithm, digital scan conversion algorithm, doppler frequency spectrum analysis algorithm, algorithm for image enhancement the described echo signal of telecommunication.
Therein in embodiment, described control and image-generating unit comprise that man-machine interaction subelement, video signal Storage ﹠ Display subelement, control subelement, activation sequence produce subelement, buffer memory subelement and multiparameter ultra sonic imaging subelement, and described activation sequence produces subelement and is connected with receiving element with described ultrasonic action by data-interface respectively with the buffer memory subelement;
Described video signal Storage ﹠ Display subelement is used for receiving the digital signal of described video signal processing unit transmission;
Described man-machine interaction subelement be used for to receive the imaging of input and controls parameter, and described imaging is controlled parameter is transferred to described control subelement and described activation sequence produces subelement to produce pulse train;
Described activation sequence produces subelement and is used for described pulse train is sent to described ultrasonic action and receiving element by data-interface;
Described buffer memory subelement is used for receiving and storing the described echo signal of telecommunication, and with described echo electric signal transmission, gives described multiparameter ultra sonic imaging subelement;
Described multiparameter ultra sonic imaging subelement is used for carrying out the multi-parameter fusion imaging according to the described echo signal of telecommunication, and described multi-parameter fusion imaging is presented at described man-machine interaction subelement.
Therein in embodiment, described ultrasonic transducer comprises a plurality of Under Ultrasonic Vibrations unit, and each Under Ultrasonic Vibration unit comprises piezoelectric and two battery lead plates that cutting half separates.
In embodiment, the frequency of described specific pulse signal is 10MHz～60MHz therein.
A kind of inner peeping type nasopharyngeal carcinoma ultrasonic imaging method comprises:
Initialization step, provide photographic head, video signal processing unit, control and image-generating unit, ultrasonic action and the receiving element and the ultrasonic transducer that are connected successively;
The video acquisition step, organism optical image by described camera collection nasopharynx inner surface, be converted into digital signal through described video signal processing unit, preserve and show to described control and image-generating unit described digital data transmission, according to described digital signal, described ultrasonic transducer is guided and locates;
Produce the pulse signal step, by described control and image-generating unit, send control instruction, control described ultrasonic action and receiving element and produce specific pulse signal;
Scanning step, produce the Endonasopharyngeal ultrasound wave of scanning by described ultrasonic transducer according to described pulse signal excitation, and the ultrasound echo signal that receives described nasopharynx internal reflection by described ultrasonic transducer, and described ultrasound echo signal is converted into the echo signal of telecommunication, and the described echo signal of telecommunication is sent to described ultrasonic action and receiving element;
Revise step, the described echo signal of telecommunication is processed; And
Image-forming step, carry out ultra sonic imaging according to the described echo signal of telecommunication after described processing.
Therein in embodiment, described ultrasonic action and receiving element comprise the excitation that is connected successively and data processor, pulse driver, impulse sender, high-voltage switch gear, low-noise amplifier, wave filter, A/D converter, described excitation is connected with image-generating unit with described control with data processor, and described high-voltage switch gear is connected with described ultrasonic transducer;
Described generation pulse signal step comprises:
Receive the control instruction of described control and image-generating unit transmission by described excitation and data processor, and according to described control instruction, control described pulse driver and the specific pulse signal of pulse generator generation, and described pulse signal is transferred to described ultrasonic transducer through described high-voltage switch gear, to encourage described ultrasonic transducer generating ultrasound wave;
Described correction step comprises:
The described echo signal of telecommunication of described ultrasonic transducer conversion after described high-voltage switch gear switching, after described low-noise amplifier, wave filter, A/D converter, excitation and data processor processes, is transferred to described control and image-generating unit.
In embodiment, described correction step comprises therein:
Described echo-signal is processed and comprised at least a processing the in employing digital filtering algorithm, time gain compensation algorithm, envelope detection algorithm, digital scan conversion algorithm, doppler frequency spectrum analysis algorithm, algorithm for image enhancement.
In embodiment, the frequency of described specific pulse signal is 10MHz～60MHz therein.
Above-mentioned inner peeping type nasopharyngeal carcinoma supersonic imaging device and method, by camera collection organism optical image, it is that ultrasonic transducer guides and locates that video image is provided, adopt ultrasonic transducer to nasopharynx inwall soft-tissue imaging, realization, to the full degree of depth accurately image of nasopharynx inwall soft tissue, has improved the accuracy that detects.And traditional nasopharynx scope adopts the optical imagery mode, can only observe color, gloss and the shape information on nasopharynx inwall top layer.
In addition, cost of manufacture is not high, and cost of equipment maintenance is cheap, and is therefore low to the patient expense, and adopt ultrasonic as imaging media, the ionizing radiation that does not have high-energy rays to cause.
Description of drawings
Fig. 1 is the structural representation of inner peeping type nasopharyngeal carcinoma supersonic imaging device in an embodiment;
Fig. 2 is that inner peeping type nasopharyngeal carcinoma supersonic imaging device is applied to the schematic diagram to the imaging of nasopharyngeal carcinoma predilection site;
Fig. 3 is the schematic diagram of ultrasonic transducer to cavum nasopharyngeum inwall soft-tissue imaging;
Fig. 4 is the internal structure schematic diagram of ultrasonic action and receiving element in an embodiment;
Fig. 5 is the internal structure schematic diagram of controlling in an embodiment with image-generating unit;
Fig. 6 is the flow chart of inner peeping type nasopharyngeal carcinoma ultrasonic imaging method in an embodiment.
The specific embodiment
Be described in detail below in conjunction with specific embodiment and the accompanying drawing technical scheme to inner peeping type nasopharyngeal carcinoma supersonic imaging device and method, so that it is clearer.
As shown in Figure 1, be the structural representation of inner peeping type nasopharyngeal carcinoma supersonic imaging device in an embodiment.This inner peeping type nasopharyngeal carcinoma supersonic imaging device, comprise photographic head 110, video signal processing unit 120, control and image-generating unit 130, ultrasonic action and the receiving element 140 and the ultrasonic transducer 150 that are connected successively.
Wherein, photographic head 110 is used for gathering the organism optical image of nasopharynx inner surface.
In the present embodiment, photographic head 110 adopts high-definition camera.This photographic head 110 can be realized the high definition optical imagery to the nasopharynx inner surface in nasopharynx is stretched in nostril, to gather the organism optical image of nasopharynx inner surface.
Video signal processing unit 120 is used for the organism optical image of this collection is processed and is converted into digital signal, and the digital data transmission after processing is to controlling and image-generating unit 130.
Control with image-generating unit 130 and be used for optimizing, preserving and show this digital signal, and according to this digital signal, obtain video image, according to this video image, ultrasonic transducer 150 is guided and locates.Control with image-generating unit 130 and also send control instruction, and control instruction is transferred to ultrasonic action and receiving element 140.
Ultrasonic action and receiving element 140 are used for receiving controls the control instruction that sends with image-generating unit 130, and according to this control instruction, produces specific pulse signal.The frequency of this pulse signal is the 10MHz(megahertz)～60MHz.
Ultrasonic transducer (ultrasonic probe) 150 is used for producing the Endonasopharyngeal ultrasound wave of scanning according to this pulse signal excitation, and receive the ultrasound echo signal of this nasopharynx internal reflection, and this ultrasound echo signal is converted into the echo signal of telecommunication, and this echo signal of telecommunication is sent to ultrasonic action and receiving element 140.In the present embodiment, ultrasonic transducer 150 comprises that a plurality of Under Ultrasonic Vibrations are first.
Ultrasonic action and receiving element 140 also are used for the echo signal of telecommunication is processed, and the echo electric signal transmission after processing is given control and image-generating unit 130.
In the present embodiment, 140 pairs of these echo signals of telecommunication of ultrasonic action and receiving element are processed and are comprised at least a processing the in employing digital filtering algorithm, time gain compensation algorithm, envelope detection algorithm, digital scan conversion algorithm, doppler frequency spectrum analysis algorithm, algorithm for image enhancement.Wherein, digital filtering algorithm, by suitable filter parameter is set, carries out bandpass filtering to the input radio frequency signal, filter away high frequency noise and low-frequency interference signal; The time gain compensation algorithm, regulate the not gain of echo-signal in the same time according to preset rules, makes the echo-signal of the different tissues degree of depth obtain different gain compensations, guarantees the concordance of different depth signal intensity; Envelope detection algorithm, adopt Hilbert transform, obtains the amplitude of radiofrequency signal, and remove the high frequency carrier composition; The digital scan conversion algorithm,, the data of pressing polar coordinate collection and preservation,, by spatial recomposition and interpolation arithmetic, be transformed into the data save mode by rectangular coordinate, so that follow-up demonstration; The doppler frequency spectrum analysis algorithm, be the radio-frequency echo wave transformation of data two-way orthogonal data by Hilbert transform, then by low pass filter and window filter, regularly choose the data of certain depth, by plural fast Fourier transform, the output spectrum data, be used for showing velocity of blood flow information.
Control with image-generating unit 130 and also be used for carrying out ultra sonic imaging according to the echo signal of telecommunication after processing.
Above-mentioned inner peeping type nasopharyngeal carcinoma supersonic imaging device is applied to the imaging of nasopharyngeal carcinoma predilection site, and as shown in Figure 2, ultrasonic transducer 150 stretches in cavum nasopharyngeum, and 22 is that nasal cavity, 24 is the nasopharyngeal carcinoma predilection site.Be illustrated in figure 3 as the schematic diagram of ultrasonic transducer to cavum nasopharyngeum inwall soft-tissue imaging, the cavum nasopharyngeum inwall has shallowly can be divided into mucous layer, fibrous layer, Musclar layer and fascia layer to often mastering.
Above-mentioned inner peeping type nasopharyngeal carcinoma supersonic imaging device, by camera collection organism optical image, it is that ultrasonic transducer guides and locates that video image is provided, adopt ultrasonic transducer to nasopharynx inwall soft-tissue imaging, realization, to the full degree of depth accurately image of nasopharynx inwall soft tissue, has improved the accuracy that detects.And traditional nasopharynx scope adopts the optical imagery mode, can only observe color, gloss and the shape information on nasopharynx inwall top layer.
As shown in Figure 4, be the internal structure schematic diagram of ultrasonic action and receiving element 140 in an embodiment.This ultrasonic action and receiving element 140 comprise the excitation that is connected successively and data processor 141, pulse driver 142, pulse generator 143, high-voltage switch gear 144, low-noise amplifier 145, wave filter 146, A/D converter 147.Excitation is connected with image-generating unit 130 with control by data-interface 160 with data processor 141, and high-voltage switch gear 144 is connected with ultrasonic transducer 150.
Excitation is used for reception with data processor 141 and controls the control instruction that sends with image-generating unit 130, and according to this control instruction control impuls driver 142 and pulse generator 143, produce specific pulse signal, and this pulse signal is transferred to ultrasonic transducer 150 through high-voltage switch gear 144, produce ultrasound wave with excitation ultrasonic transducer 150.The signal prevention is large to be processed pulse driver 142 for the pulse generator 143 of next stage is done.The similar power amplifier of pulse generator 143 or high-power electronic switch.
Wherein, 145 pairs of echo signals of telecommunication of low-noise amplifier carry out processing and amplifying, and 146 pairs of echo signals of telecommunication of wave filter carry out Filtering Processing, and the echo signal of telecommunication that A/D converter 147 will be simulated is converted into the echo signal of telecommunication of numeral.The echo signal of telecommunication of this excitation and 141 pairs of numerals of data processor carries out time gain compensation algorithm process, envelope detection algorithm processing, digital scan conversion algorithm process, doppler frequency spectrum analysis algorithm process, image increase algorithm process etc.The echo signal of telecommunication after processed transfers to and controls and image-generating unit 130 by data-interface.In addition, excitation is also carried out the synthetic processing of light beam to the echo signal of telecommunication of numeral with data processor 141.
As shown in Figure 5, control with image-generating unit 130 and comprise that the video signal Storage ﹠ Display subelement 131, man-machine interaction subelement 132, control subelement 133, the activation sequence that are connected successively produce subelement 134, buffer memory subelement 135 and multiparameter ultra sonic imaging subelement 136.Wherein, activation sequence generation subelement 134 is connected with receiving element 140 with ultrasonic action by data-interface 160 respectively with buffer memory subelement 135.Video signal Storage ﹠ Display subelement 131 is connected with video signal processing unit 120.
Video signal Storage ﹠ Display subelement 131 is used for the digital signal of receiving video signals processing unit 120 transmission.
Man-machine interaction subelement 132 is used for receiving the imaging of input and controls parameter, and parameter is controlled in this imaging is transferred to and controls subelement 133 and activation sequence produces subelement 134 to produce pulse train.This imaging is controlled parameter and is referred to encourage the parameter that produces pulse train, as the pulse period.Man-machine interaction subelement 132 comprises the interactive devices such as keyboard, mouse, touch screen, display.
Activation sequence produces subelement 134 and is used for this pulse train is sent to ultrasonic action and receiving element 140 by data-interface.
Multiparameter ultra sonic imaging subelement 136 is used for carrying out the multi-parameter fusion imaging according to this echo signal of telecommunication, and this multi-parameter fusion imaging is presented at man-machine interaction subelement 132.This multiparameter comprises the B-MODE imaging parameters, frequency spectrum parameter, blood flow Doppler frequency shift parameter etc.This multi-parameter fusion imaging is imaged as the master with B ultrasonic.Man-machine interaction subelement 132 can show the real-time color image that photographic head 110 gathers and the ultrasonic B ultrasonic image that carries out ultra sonic imaging according to the echo signal of telecommunication.
Above-mentioned inner peeping type nasopharyngeal carcinoma supersonic imaging device, cost of manufacture is not high, cost of equipment maintenance is cheap, and is therefore low to the patient expense, and adopt ultrasonic as imaging media, the ionizing radiation that does not have high-energy rays to cause.
In addition, above-mentioned inner peeping type nasopharyngeal carcinoma supersonic imaging device can be applicable to early stage triggering nasopharyngeal carcinoma and detects, because if tumor tissues is grown in mucosa, and also do not cause the obvious profile variation of nasopharynx inwall, no matter adopt nasopharyngeal endoscope or CT or MRI all to be difficult to nasopharyngeal carcinoma is carried out imaging, and adopt this inner peeping type nasopharyngeal carcinoma supersonic imaging device to carry out imaging to detecting neoplastic lesion position and size.
As shown in Figure 6, be the flow chart of inner peeping type nasopharyngeal carcinoma ultrasonic imaging method in an embodiment.This inner peeping type nasopharyngeal carcinoma ultrasonic imaging method comprises:
Step S610, initialization step, provide photographic head, video signal processing unit, control and image-generating unit, ultrasonic action and the receiving element and the ultrasonic transducer that are connected successively.
Concrete, this ultrasonic action and receiving element comprise the excitation that is connected successively and data processor, pulse driver, impulse sender, high-voltage switch gear, low-noise amplifier, wave filter, A/D converter, this excitation is connected with image-generating unit with this control with data processor, and this high-voltage switch gear is connected with this ultrasonic transducer.
Step S620, the video acquisition step, organism optical image by this camera collection nasopharynx inner surface, be converted into digital signal through described video signal processing unit, this digital data transmission is controlled with image-generating unit and preserved and show to this, according to this digital signal, this ultrasonic transducer is guided and locates.
Step S630, produce the pulse signal step, by this control and image-generating unit, sends control instruction, controls this ultrasonic action and receiving element and produce specific pulse signal.
In the present embodiment, producing the pulse signal step comprises: the control instruction that receives this control and image-generating unit transmission by this excitation and data processor, and according to this control instruction, control this pulse driver and the specific pulse signal of pulse generator generation, and this pulse signal is transferred to this ultrasonic transducer through this high-voltage switch gear, to encourage this ultrasonic transducer generating ultrasound wave.
The frequency of this pulse signal is the 10MHz(megahertz)～60MHz.
Step S640, scanning step, produce the Endonasopharyngeal ultrasound wave of scanning by this ultrasonic transducer according to this pulse signal excitation, and the ultrasound echo signal that receives this nasopharynx internal reflection by this ultrasonic transducer, and this ultrasound echo signal is converted into the echo signal of telecommunication, and this echo signal of telecommunication is sent to this ultrasonic action and receiving element.
Step S650, revise step, and this echo signal of telecommunication is processed.
In the present embodiment, this correction step comprises: this echo signal of telecommunication that this ultrasonic transducer is transformed is after this high-voltage switch gear switching, after this low-noise amplifier, wave filter, A/D converter, excitation and data processor processes, be transferred to this control and image-generating unit.
In addition, this correction step comprises: this echo-signal is processed and comprised at least a processing the in employing digital filtering algorithm, time gain compensation algorithm, envelope detection algorithm, digital scan conversion algorithm, doppler frequency spectrum analysis algorithm, algorithm for image enhancement.
Step S660, image-forming step, carry out ultra sonic imaging according to this echo signal of telecommunication after this processing.
Above-mentioned inner peeping type nasopharyngeal carcinoma ultrasonic imaging method, by camera collection organism optical image, it is that ultrasonic transducer guides and locates that video image is provided, adopt ultrasonic transducer to nasopharynx inwall soft-tissue imaging, realization, to the full degree of depth accurately image of nasopharynx inwall soft tissue, has improved the accuracy that detects.And traditional nasopharynx scope adopts the optical imagery mode, can only observe color, gloss and the shape information on nasopharynx inwall top layer.
The above embodiment has only expressed several embodiment of the present invention, and it describes comparatively concrete and detailed, but can not therefore be interpreted as the restriction to the scope of the claims of the present invention.Should be pointed out that for the person of ordinary skill of the art, without departing from the inventive concept of the premise, can also make some distortion and improvement, these all belong to protection scope of the present invention.Therefore, the protection domain of patent of the present invention should be as the criterion with claims.
Claims (10)
1. an inner peeping type nasopharyngeal carcinoma supersonic imaging device, is characterized in that, comprising:
Photographic head, for the organism optical image that gathers the nasopharynx inner surface;
Video signal processing unit, be connected with described photographic head, is used for the organism optical image of described collection is processed and is converted into digital signal;
Control and image-generating unit, with described video signal processing unit, be connected, be used for preserving and showing described digital signal, and send control instruction;
Ultrasonic action and receiving element, be connected with image-generating unit with described control, is used for receiving the control instruction of described control and image-generating unit transmission, and according to described control instruction, produces specific pulse signal, and carry out the processing of ultrasound echo signal;
Ultrasonic transducer, be connected with receiving element with described ultrasonic action, be used for producing the Endonasopharyngeal ultrasound wave of scanning according to described pulse signal excitation, and receive the ultrasound echo signal of described nasopharynx inner tissue reflection, and described ultrasound echo signal is converted into the echo signal of telecommunication, and the described echo signal of telecommunication is sent to described ultrasonic action and receiving element;
Described ultrasonic action and receiving element also are used for the described echo signal of telecommunication is processed, and the echo electric signal transmission after processing is given described control and image-generating unit; And
Described control and image-generating unit also are used for carrying out ultra sonic imaging according to the described echo signal of telecommunication after processing, and according to described digital signal, obtain video image, according to described video image, described ultrasonic transducer are guided and locate.
2. inner peeping type nasopharyngeal carcinoma supersonic imaging device according to claim 1, it is characterized in that, described ultrasonic action and receiving element comprise the excitation that is connected successively and data processor, pulse driver, impulse sender, high-voltage switch gear, low-noise amplifier, wave filter, A/D converter, described excitation is connected with image-generating unit with described control with data processor, and described high-voltage switch gear is connected with described ultrasonic transducer;
Described excitation and data processor are used for receiving the control instruction of described control and image-generating unit transmission, and according to described control instruction, control described pulse driver and the specific pulse signal of pulse generator generation, and described pulse signal is transferred to described ultrasonic transducer through described high-voltage switch gear, to encourage described ultrasonic transducer generating ultrasound wave;
The described echo signal of telecommunication that described ultrasonic transducer transforms after described high-voltage switch gear switching, after described low-noise amplifier, wave filter, A/D converter, excitation and data processor processes, is transferred to described control and image-generating unit.
3. inner peeping type nasopharyngeal carcinoma supersonic imaging device according to claim 1, it is characterized in that, described ultrasonic action and receiving element are processed and are comprised at least a processing the in employing digital filtering algorithm, time gain compensation algorithm, envelope detection algorithm, digital scan conversion algorithm, doppler frequency spectrum analysis algorithm, algorithm for image enhancement the described echo signal of telecommunication.
4. inner peeping type nasopharyngeal carcinoma supersonic imaging device according to claim 1, it is characterized in that, described control and image-generating unit comprise that man-machine interaction subelement, video signal Storage ﹠ Display subelement, control subelement, activation sequence produce subelement, buffer memory subelement and multiparameter ultra sonic imaging subelement, and described activation sequence produces subelement and is connected with receiving element with described ultrasonic action by data-interface respectively with the buffer memory subelement;
Described video signal Storage ﹠ Display subelement is used for receiving the digital signal of described video signal processing unit transmission;
Described man-machine interaction subelement be used for to receive the imaging of input and controls parameter, and described imaging is controlled parameter is transferred to described control subelement and described activation sequence produces subelement to produce pulse train;
Described activation sequence produces subelement and is used for described pulse train is sent to described ultrasonic action and receiving element by data-interface;
Described buffer memory subelement is used for receiving and storing the described echo signal of telecommunication, and with described echo electric signal transmission, gives described multiparameter ultra sonic imaging subelement;
Described multiparameter ultra sonic imaging subelement is used for carrying out the multi-parameter fusion imaging according to the described echo signal of telecommunication, and described multi-parameter fusion imaging is presented at described man-machine interaction subelement.
5. inner peeping type nasopharyngeal carcinoma supersonic imaging device according to claim 1, is characterized in that, described ultrasonic transducer comprises that a plurality of Under Ultrasonic Vibrations are first.
6. inner peeping type nasopharyngeal carcinoma supersonic imaging device according to claim 1, is characterized in that, the frequency of described specific pulse signal is 10MHz～60MHz.
7. inner peeping type nasopharyngeal carcinoma ultrasonic imaging method comprises:
Initialization step, provide photographic head, video signal processing unit, control and image-generating unit, ultrasonic action and the receiving element and the ultrasonic transducer that are connected successively;
The video acquisition step, organism optical image by described camera collection nasopharynx inner surface, be converted into digital signal through described video signal processing unit, preserve and show to described control and image-generating unit described digital data transmission, according to described digital signal, described ultrasonic transducer is guided and locates;
Produce the pulse signal step, by described control and image-generating unit, send control instruction, control described ultrasonic action and receiving element and produce specific pulse signal;
Scanning step, produce the Endonasopharyngeal ultrasound wave of scanning by described ultrasonic transducer according to described pulse signal excitation, and the ultrasound echo signal that receives described nasopharynx internal reflection by described ultrasonic transducer, and described ultrasound echo signal is converted into the echo signal of telecommunication, and the described echo signal of telecommunication is sent to described ultrasonic action and receiving element;
Revise step, the described echo signal of telecommunication is processed; And
Image-forming step, carry out ultra sonic imaging according to the described echo signal of telecommunication after described processing.
8. inner peeping type nasopharyngeal carcinoma ultrasonic imaging method according to claim 7, it is characterized in that, described ultrasonic action and receiving element comprise the excitation that is connected successively and data processor, pulse driver, impulse sender, high-voltage switch gear, low-noise amplifier, wave filter, A/D converter, described excitation is connected with image-generating unit with described control with data processor, and described high-voltage switch gear is connected with described ultrasonic transducer;
Described generation pulse signal step comprises:
Receive the control instruction of described control and image-generating unit transmission by described excitation and data processor, and according to described control instruction, control described pulse driver and the specific pulse signal of pulse generator generation, and described pulse signal is transferred to described ultrasonic transducer through described high-voltage switch gear, to encourage described ultrasonic transducer generating ultrasound wave;
Described correction step comprises:
The described echo signal of telecommunication of described ultrasonic transducer conversion after described high-voltage switch gear switching, after described low-noise amplifier, wave filter, A/D converter, excitation and data processor processes, is transferred to described control and image-generating unit.
9. inner peeping type nasopharyngeal carcinoma ultrasonic imaging method according to claim 7, is characterized in that, described correction step comprises:
Described echo-signal is processed and comprised at least a processing the in employing digital filtering algorithm, time gain compensation algorithm, envelope detection algorithm, digital scan conversion algorithm, doppler frequency spectrum analysis algorithm, algorithm for image enhancement.
10. inner peeping type nasopharyngeal carcinoma ultrasonic imaging method according to claim 7, is characterized in that, the frequency of described specific pulse signal is 10MHz～60MHz.
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| CN201310330411.2A CN103385736B (en) | 2013-07-31 | 2013-07-31 | Inner peeping type nasopharyngeal carcinoma supersonic imaging device |
| PCT/CN2013/081350 WO2015013995A1 (en) | 2013-07-31 | 2013-08-13 | Endoscopic ultrasonic imaging device and method for nasopharynx cancer |
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| CN201310330411.2A CN103385736B (en) | 2013-07-31 | 2013-07-31 | Inner peeping type nasopharyngeal carcinoma supersonic imaging device |
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| CN103385736B (en) | 2015-07-29 |
| WO2015013995A1 (en) | 2015-02-05 |
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