CN103381247B - Traditional Chinese medicinal composition for treating psoriasis - Google Patents
Traditional Chinese medicinal composition for treating psoriasis Download PDFInfo
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- CN103381247B CN103381247B CN201310146119.5A CN201310146119A CN103381247B CN 103381247 B CN103381247 B CN 103381247B CN 201310146119 A CN201310146119 A CN 201310146119A CN 103381247 B CN103381247 B CN 103381247B
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Abstract
The invention discloses a traditional Chinese medicinal mixture for treating psoriasis. The traditional Chinese medicinal mixture is prepared from the following medicines by weight: radix sileris, bighead atractylodes rhizome, campsis grandiflora, catnip, honeysuckle flower, coptis, Poria cocos, heydyotis, dandelion, gypsum, motherwort fruit, broom cypress fruit, buckwheat, radix paeoniae rubrathe, rehmanniae radix, cortex of Chinese dittany root, coix seed, Euonymus alatus and sophora flavescens. The traditional Chinese medicinal mixture is convenient to use, has fast curative effect, has little side-effect, is easy to observe curative effect and side effect, and is beneficial to long-term treatment.
Description
Technical field
The invention belongs to technical field of Chinese medicine, be specifically related to one and be used for the treatment of psoriatic Chinese medicine composition.
Background technology
Psoriasis (Psoriasis) is commonly called as psoriasis, and motherland's medical science claims psoriasis to be “ Bai Mange ", be common chronic, recurrent, struvite dermatosis.It is characterized in that the pimple occurring differing in size, erythema, surface coverage silvery white squama, and clear border is apt to occur in scalp, and extremity stretch side and back.Male is more than women.Winter in spring easily recurs or increases the weight of, and many alleviations summer and autumn.。
Primary disease there is no satisfied Therapeutic Method at present, and majority can only reach short term effect, but can not prevent recurrence.
1. first general treatement establishes the confidence of patient, stabilizing the emotions.Eliminate the factor of bringing out this onste.Positive infection control.Avoid pungent diet and drink, carrying out phase patient and forbid the stronger medicine for external use of zest.
2. whole body therapeutic all should based on whole body therapeutic to any type general property psoriasis, and the principle of whole body therapeutic will select side effect little, the medicine that recurrence period is long.The change of routine observation Liver and kidney function and routine blood test during medication.
Summary of the invention
goal of the invention:the object of this invention is to provide one and be used for the treatment of psoriatic Traditional Chinese drug mixture.
technical scheme: for solving the problems of the technologies described above, the present invention adopts following technical scheme: one is used for the treatment of psoriatic Traditional Chinese drug mixture, it is characterized in that being made up of the medicine of following weight portion: Radix Saposhnikoviae 10-40 part, Rhizoma Coptidis 15-45 part, Rhizoma Atractylodis Macrocephalae 10-40 part, Flos Campsis 5-20 part, Herba Schizonepetae 10-40 part, Flos Lonicerae 15-45 part, Poria 10-40 part, Herba Taraxaci 15-50 part, Gypsum Fibrosum 10-30 part, Fructus Leonuri 10-40 part, Fructus Kochiae 10-40 part, Semen Fagopyri Esculenti 10-40 part, Radix Paeoniae Rubra 10-40 part, Radix Rehmanniae 10-40 part, Cortex Dictamni 20-60 part, Semen Coicis 20-60 part, Ramulus Euonymi 5-30 part, Radix Sophorae Flavescentis 10-40 part, Herba Hedyotidis Diffusae 15-45 part.
For solving the problems of the technologies described above further, the preferred version of said medicine weight portion is: Radix Saposhnikoviae 20-30 part, Rhizoma Coptidis 25-35 part, Rhizoma Atractylodis Macrocephalae 20-30 part, Flos Campsis 10-15 part, Herba Schizonepetae 20-30 part, Flos Lonicerae 25-35 part, Poria 20-30 part, Herba Taraxaci 20-45 part, Gypsum Fibrosum 15-25 part, Fructus Leonuri 20-30 part, Fructus Kochiae 20-30 part, Semen Fagopyri Esculenti 20-30 part, Radix Paeoniae Rubra 20-30 part, Radix Rehmanniae 20-30 part, Cortex Dictamni 30-50 part, Semen Coicis 30-50 part, Ramulus Euonymi 10-20 part, Radix Sophorae Flavescentis 20-30 part, Herba Hedyotidis Diffusae 25-35 part.
For solving the problems of the technologies described above further, the preferred plan of said medicine weight portion is: Radix Saposhnikoviae 30 parts, Rhizoma Coptidis 30 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Flos Campsis 15 parts, Herba Schizonepetae 25 parts, Flos Lonicerae 30 parts, 25 parts, Poria, Herba Taraxaci 40 parts, Gypsum Fibrosum 20 parts, Fructus Leonuri 25 parts, the Fructus Kochiae 25 parts, 25 parts, Semen Fagopyri Esculenti, Radix Paeoniae Rubra 25 parts, 25 parts, the Radix Rehmanniae, Cortex Dictamni 40 parts, Semen Coicis 40 parts, Ramulus Euonymi 15 parts, Radix Sophorae Flavescentis 25 parts, Herba Hedyotidis Diffusae 30 parts.
Traditional Chinese drug mixture described above according to Chinese medicine conventional formulation techniques make pill, sublimed preparation, powder, tablet, unguentum,
Decoction and capsule fill the different oral medicine dosage form of powder.
Traditional Chinese drug mixture described above is also containing drug excipient.
Traditional Chinese drug mixture described above is used for the application as treatment psoriasis disease.
The principles of formulating prescriptions of Traditional Chinese drug mixture of the present invention are: circulate with regulating blood flow, the removing toxic substances of clearing away heart-fire, expelling wind and removing dampness, kidney tonifying, antipruritic, the cooling blood and dissolving purpura of town pain, enhancement telangiectasis, improve immune function of human body, thus reach the psoriatic object for the treatment of.The present invention has that compatibility of drugs is proper, reasonable recipe, according to the Chinese medicine of the configurable various dose of the difference of the course of disease; Novel formula, drug effect is complementary, with low cost, has good therapeutic effect, and have no side effect to psoriasis.
beneficial effect:traditional Chinese drug mixture result in clinical application of the present invention shows, tool has the following advantages:
1, the Traditional Chinese drug mixture each component that the present invention selects meets the regulation of the Drug Administration Law of People's Republic of China, utilizes comprehensive function treatment and the prevention psoriasis disease of each taste Chinese medicine, harmless to human non-toxic.Show that underproof animal has no any toxic reaction through the acute toxicity test of white mice and rat and accumulation toxicity test, compare zero difference through anatomic observation hemogram, liver function, each organs and tissues morphology finding with matched group, prove that its safety of medicine is reliable.
2, Traditional Chinese drug mixture preparation medication of the present invention is convenient, curative effect is fast, side effect is very little, and easy observe the curative effect and side reaction, be beneficial to long-term treatment.
Traditional Chinese drug mixture of the present invention is further illustrated to the psoriatic effect for the treatment of below by clinical practice.
According to psoriatic clinical manifestation and pathological characters,
Psoriasis vulgaris: erythra generally occurs in scalp, trunk, extremity stretch side, on skin, occur red pimple, and expansion is fused into patch or speckle gradually, there are thicker silvery white phosphorus bits on surface, out-of-shape, what have has map or island sample outward appearance, some skin lesion are less, more, in Caulis et folium pavettae hongkongensis outward appearance, squama layer one deck comes off, wipe scurf gently off and can see the red film of very thin one deck, strike off red film and can see slight petechia, there is person for blood dew, medically make again sieve-like hemorrhage, homeliness type psoriasis Clinical symptoms that Here it is.
Two. the selection of case
Case all be can be used as the patient meeting above-mentioned disease observe, especially weak and sickly, middle-aged and elderly people, women, child are observed as first-selected case especially; The method of observing then carries out complete observation by the method for hoping, asking, hearing, cutting to patient; And, sex of all ages for the heavier patient of the state of an illness, without exception as the direct study subject observing treatment.
Three. administrated method
According to the severe extent of psoriatic, the length of sick time, with oral of the present invention in adopting
Traditional Chinese drug mixture carries out treatment psoriasis, and its method of administration is: three times on the one, each 6-12 gram, warm water delivery service; Ante cibum, one after each meal.The phase that just takes is 30 days, and dose can double, and after this dose is taken medicine continuously routinely, within three months, is to carry out observing and Outcome measure a course for the treatment of.Traditional Chinese drug mixture of the present invention is because Chinese medicine preparation, reasonable recipe, prove to have no side effect through clinical application toxicity test, therefore, patient can take Chinese patent medicine of the present invention the long period at treatments period, and without the need to dieting in period in a medicine diet.
Four. clinical treatment outcome
Traditional Chinese drug mixture of the present invention, its clinical treatment outcome is: recovery from illness (more than 1 year non-recidivist is observed in drug withdrawal) 110 example, and cure rate is 39.57%; Effective (more than 1 year non-recidivist is observed in drug withdrawal) 96 is routine, and obvious effective rate is 34.53%; Effectively (symptom obviously alleviates scurf major part and comes off, and still has the small part silver bits person of not moving back) 54 examples, effective percentage is 19.42%; Invalid (take medicine not alleviator 2 courses for the treatment of) 18 is routine, inefficiency 6.47%; Total effective rate is 93.53%, there are no any toxic and side effects.
Detailed description of the invention
Embodiment 1
Traditional Chinese drug mixture described in the present embodiment presses row weight portion to take each Chinese crude drug: Radix Saposhnikoviae 25 parts, the Rhizoma Atractylodis Macrocephalae 10 parts, Flos Campsis 15 parts, Herba Schizonepetae 10 parts, Flos Lonicerae 15 parts, Rhizoma Coptidis 15 parts, 10 parts, Poria, Herba Hedyotidis Diffusae 15 parts, Herba Taraxaci 35 parts, Gypsum Fibrosum 18 parts, Fructus Leonuri 10 parts, the Fructus Kochiae 10 parts, 20 parts, Semen Fagopyri Esculenti, Radix Paeoniae Rubra 10 parts, 10 parts, the Radix Rehmanniae, Cortex Dictamni 20 parts, Semen Coicis 20 parts, Ramulus Euonymi 25 parts, Radix Sophorae Flavescentis 10 parts.
Traditional Chinese drug mixture described in the present embodiment is that its preparation technology is: the pharmaceutical methods that above-mentioned each medicinal raw material conveniently prepares sublimed preparation is made sublimed preparation as the psoriatic endo-medicine for the treatment of.
Embodiment 2
Press row weight portion and take each medical material: Radix Saposhnikoviae 20 parts, the Rhizoma Atractylodis Macrocephalae 40 parts, Flos Campsis 10 parts, Herba Schizonepetae 40 parts, Flos Lonicerae 45 parts, Rhizoma Coptidis 45 parts, 40 parts, Poria, Herba Hedyotidis Diffusae 45 parts, Herba Taraxaci 45 parts, Gypsum Fibrosum 15 parts, Fructus Leonuri 40 parts, the Fructus Kochiae 40 parts, 20 parts, Semen Fagopyri Esculenti, Radix Paeoniae Rubra 40 parts, 40 parts, the Radix Rehmanniae, Cortex Dictamni 60 parts, Semen Coicis 60 parts, Ramulus Euonymi 20 parts, Radix Sophorae Flavescentis 40 parts.
Traditional Chinese drug mixture described in the present embodiment is that its preparation technology is: the pharmaceutical methods that above-mentioned each medicinal raw material conveniently prepares powder is made packeted powders as the psoriatic endo-medicine for the treatment of.
Embodiment 3
Press row weight portion and take each medical material: Radix Saposhnikoviae 25 parts, the Rhizoma Atractylodis Macrocephalae 20 parts, Flos Campsis 20 parts, Herba Schizonepetae 20 parts, Flos Lonicerae 25 parts, Rhizoma Coptidis 25 parts, 20 parts, Poria, Herba Hedyotidis Diffusae 25 parts, Herba Taraxaci 45 parts, Gypsum Fibrosum 20 parts, Fructus Leonuri 20 parts, the Fructus Kochiae 20 parts, 25 parts, Semen Fagopyri Esculenti, Radix Paeoniae Rubra 20 parts, 20 parts, the Radix Rehmanniae, Cortex Dictamni 30 parts, Semen Coicis 30 parts, Ramulus Euonymi 25 parts, Radix Sophorae Flavescentis 20 parts.
Traditional Chinese drug mixture described in the present embodiment is that its preparation technology is: the pharmaceutical methods that above-mentioned each medicinal raw material conveniently prepares capsule is made capsule as the psoriatic endo-medicine for the treatment of.
Embodiment 4
Press row weight portion and take each medical material: Radix Saposhnikoviae 30 parts, the Rhizoma Atractylodis Macrocephalae 30 parts, Flos Campsis 15 parts, Herba Schizonepetae 30 parts, Flos Lonicerae 35 parts, Rhizoma Coptidis 35 parts, 30 parts, Poria, Herba Hedyotidis Diffusae 35 parts, Herba Taraxaci 35 parts, Gypsum Fibrosum 25 parts, Fructus Leonuri 30 parts, the Fructus Kochiae 30 parts, 30 parts, Semen Fagopyri Esculenti, Radix Paeoniae Rubra 30 parts, 30 parts, the Radix Rehmanniae, Cortex Dictamni 50 parts, Semen Coicis 50 parts, Ramulus Euonymi 30 parts, Radix Sophorae Flavescentis 30 parts.
Traditional Chinese drug mixture described in the present embodiment is as the psoriatic endo-medicine for the treatment of, its preparation technology is: the pharmaceutical methods that above-mentioned each medicinal raw material conveniently prepares tablet is made tablet, (as conventional tablet, sugar coated tablet, film coated tablet etc.), and give conventional drug excipient (as starch, sucrose, lactose, calcium stearate, magnesium stearate etc.).
Embodiment 5
Press row weight portion and take each medical material: Radix Saposhnikoviae 28 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Flos Campsis 20 parts, Herba Schizonepetae 25 parts, Flos Lonicerae 30 parts, Rhizoma Coptidis 30 parts, 25 parts, Poria, Herba Hedyotidis Diffusae 30 parts, Herba Taraxaci 40 parts, Gypsum Fibrosum 25 parts, Fructus Leonuri 25 parts, the Fructus Kochiae 25 parts, 25 parts, Semen Fagopyri Esculenti, Radix Paeoniae Rubra 25 parts, 25 parts, the Radix Rehmanniae, Cortex Dictamni 40 parts, Semen Coicis 40 parts, Ramulus Euonymi 25 parts, Radix Sophorae Flavescentis 25 parts.
Traditional Chinese drug mixture described in the present embodiment is that its preparation technology is: the pharmaceutical methods that above-mentioned each medicinal raw material conveniently prepares pill is made pill as the psoriatic endo-medicine for the treatment of, and gives conventional drug excipient.
Embodiment 6
Press row weight portion and take each medical material: Radix Saposhnikoviae 25 parts, the Rhizoma Atractylodis Macrocephalae 15 parts, Flos Campsis 15 parts, Herba Schizonepetae 15 parts, Flos Lonicerae 30 parts, Rhizoma Coptidis 30 parts, 15 parts, Poria, Herba Hedyotidis Diffusae 30 parts, Herba Taraxaci 40 parts, Gypsum Fibrosum 30 parts, Fructus Leonuri 15 parts, the Fructus Kochiae 15 parts, 35 parts, Semen Fagopyri Esculenti, Radix Paeoniae Rubra 15 parts, 15 parts, the Radix Rehmanniae, Cortex Dictamni 40 parts, Semen Coicis 40 parts, Ramulus Euonymi 15 parts, Radix Sophorae Flavescentis 15 parts.
Traditional Chinese drug mixture described in the present embodiment is that its preparation technology is: the pharmaceutical methods that above-mentioned each medicinal raw material conveniently prepares granule is made granule as the psoriatic endo-medicine for the treatment of.
Claims (5)
1. be used for the treatment of a psoriatic Traditional Chinese drug mixture, it is characterized in that being made up of the medicine of following weight portion: Radix Saposhnikoviae 10-40 part, Rhizoma Coptidis 15-45 part, Rhizoma Atractylodis Macrocephalae 10-40 part, Flos Campsis 5-20 part, Herba Schizonepetae 10-40 part, Flos Lonicerae 15-45 part, Poria 10-40 part, Herba Taraxaci 15-50 part, Gypsum Fibrosum 10-30 part, Fructus Leonuri 10-40 part, Fructus Kochiae 10-40 part, Semen Fagopyri Esculenti 10-40 part, Radix Paeoniae Rubra 10-40 part, Radix Rehmanniae 10-40 part, Cortex Dictamni 20-60 part, Semen Coicis 20-60 part, Ramulus Euonymi 5-30 part, Radix Sophorae Flavescentis 10-40 part, Herba Hedyotidis Diffusae 15-45 part.
2. be according to claim 1ly used for the treatment of psoriatic Traditional Chinese drug mixture, it is characterized in that being made up of the medicine of following weight portion: Radix Saposhnikoviae 20-30 part, Rhizoma Coptidis 25-35 part, Rhizoma Atractylodis Macrocephalae 20-30 part, Flos Campsis 10-15 part, Herba Schizonepetae 20-30 part, Flos Lonicerae 25-35 part, Poria 20-30 part, Herba Taraxaci 20-45 part, Gypsum Fibrosum 15-25 part, Fructus Leonuri 20-30 part, Fructus Kochiae 20-30 part, Semen Fagopyri Esculenti 20-30 part, Radix Paeoniae Rubra 20-30 part, Radix Rehmanniae 20-30 part, Cortex Dictamni 30-50 part, Semen Coicis 30-50 part, Ramulus Euonymi 10-20 part, Radix Sophorae Flavescentis 20-30 part, Herba Hedyotidis Diffusae 25-35 part.
3. be according to claim 1ly used for the treatment of psoriatic Traditional Chinese drug mixture, it is characterized in that being made up of the medicine of following weight portion: Radix Saposhnikoviae 30 parts, Rhizoma Coptidis 30 parts, the Rhizoma Atractylodis Macrocephalae 25 parts, Flos Campsis 15 parts, Herba Schizonepetae 25 parts, Flos Lonicerae 30 parts, 25 parts, Poria, Herba Taraxaci 40 parts, Gypsum Fibrosum 20 parts, Fructus Leonuri 25 parts, the Fructus Kochiae 25 parts, 25 parts, Semen Fagopyri Esculenti, Radix Paeoniae Rubra 25 parts, 25 parts, the Radix Rehmanniae, Cortex Dictamni 40 parts, Semen Coicis 40 parts, Ramulus Euonymi 15 parts, Radix Sophorae Flavescentis 25 parts, Herba Hedyotidis Diffusae 30 parts.
4. according to the arbitrary claim of claims 1 to 3, be used for the treatment of psoriatic Traditional Chinese drug mixture, it is characterized in that making the different oral medicine dosage form of pill, sublimed preparation, powder, tablet, unguentum, decoction and capsule dress powder according to Chinese medicine conventional formulation techniques.
5. the psoriatic Traditional Chinese drug mixture that is used for the treatment of described in any one of claim 1-3 is preparing the application for the treatment of psoriatic medicine.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1879784A (en) * | 2006-05-15 | 2006-12-20 | 左建华 | A Chinese medicine for treating psoriasis |
| CN101642525A (en) * | 2008-08-05 | 2010-02-10 | 柏寿权 | Medicament for treating psoriasis vulgaris |
| CN102423433A (en) * | 2011-11-29 | 2012-04-25 | 王莲芬 | Traditional Chinese drug mixture for treating psoriasis |
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- 2013-04-25 CN CN201310146119.5A patent/CN103381247B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1879784A (en) * | 2006-05-15 | 2006-12-20 | 左建华 | A Chinese medicine for treating psoriasis |
| CN101642525A (en) * | 2008-08-05 | 2010-02-10 | 柏寿权 | Medicament for treating psoriasis vulgaris |
| CN102423433A (en) * | 2011-11-29 | 2012-04-25 | 王莲芬 | Traditional Chinese drug mixture for treating psoriasis |
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