CN103372135A - Chinese medicinal composition treating cardiovascular and cerebrovascular diseases caused by heart-kidney imbalance - Google Patents

Chinese medicinal composition treating cardiovascular and cerebrovascular diseases caused by heart-kidney imbalance Download PDF

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CN103372135A
CN103372135A CN2013102825540A CN201310282554A CN103372135A CN 103372135 A CN103372135 A CN 103372135A CN 2013102825540 A CN2013102825540 A CN 2013102825540A CN 201310282554 A CN201310282554 A CN 201310282554A CN 103372135 A CN103372135 A CN 103372135A
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radix
kidney
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chinese medicine
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CN103372135B (en
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姜帆
张帅
魏龙海
张华君
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张帅
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Abstract

The invention relates to the technical field of traditional Chinese medicines. The invention aims at providing a Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases caused by heart-kidney imbalance. The Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases caused by heart-kidney imbalance is characterized by containing the following crude drugs in parts by weight: 8-12 parts of deer heart, 3-5 parts of bunge auriculate root, 10-30 parts of polygala tenuifolia, 10-35 parts of Chinese angelica, 10-30 parts of poria cocos and 10-20 parts of salviae miltiorrhizae. Statistics shows that when the Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases caused by heart-kidney imbalance is effective to 29 patients, produces an apparent effect to 27 patients and is invalid to 3 patients when being orally taken for treating cardiovascular and cerebrovascular diseases caused by heart-kidney imbalance, effective rate is 90.6%, significant efficiency is 84.3% and no adverse reaction record is produced as the Chinese medicinal composition for treating cardiovascular and cerebrovascular diseases caused by heart-kidney imbalance is taken.

Description

A kind of Chinese medicine composition for the treatment of the cardiovascular and cerebrovascular disease that syndrome of disharmony between heart and kidney causes
Technical field
The present invention relates to technical field of Chinese medicines, refer to that specifically rheumatic heart disease, coronary heart disease, arteriosclerosis, myocardial ischemia, cerebral blood supply insufficiency, arrhythmia, heart failure, tachycardia, angina pectoris and elimination that a kind for the treatment of brought out by disarmony between the heart and kidney are uncomfortable in chest, breathe hard, have palpitation, the Chinese medicine composition of weak, cardiopalmus, insomnia, dizziness, the clinical symptoms such as suffer from a deficiency of the kidney.
Background technology
Syndrome of disharmony between heart and kidney be because of heart kidney both helped the imbalance due to disease.The traditional Chinese medical science has constantly held: the heart occupies the part of the body cavity above the diaphragm housing the heart and lungs and belongs to fire; Kidney occupies the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels and belongs to water.Heart the yang aspect of yang drops to kidney, energy replenishing vital QI with drugs of warm nature kidney yang; The kidney the yin aspect of yin rises to the heart, then can conserve the heart-yin.Under normal circumstances, heart-fire and the mutual coordination between ascending and descending of kidney water, each other traffic keeps dynamic equilibrium.Disarmony between the heart and kidney is damaged by excess of seven emotions, and susceptible to anger is worried sad probably frightened.Worried think angry, anxiety making QI depressed, rage causing upward adverse flow of liver-QI, sorrow endlessly, sad kidney; Seven emotions pent-up, stagnated QI transforming into fire, kidney falls under water, and flaming up of heart-fire is all healthy energy and hinders.Cause all diseases around body, tired disease is on the point of and is sent out.  
Syndrome of disharmony between heart and kidney generally betides the male, is called again the modern times " affluenza ".The traditional Chinese medical science to the cause of disease of syndrome of disharmony between heart and kidney be summarized as suffer from a deficiency of the kidney lose support, six aspects such as weakness due to chronic disease, work and rest are improper, seven emotions trauma, exopathogen invasion, overdose.Consumption of YIN caused by febrile disease, damage of kidney-YIN, heart-fire is recklessly acted, and upsets the mind; Overstrain, body constitution is thin and weak, and is dispirited, and god is not hiding; Eating and drinking without temperance, excessive drinking are immoderate, and expectorant is given birth to intrinsic heat and fire-transformation, the impairment of the spleen and to grow expectorant turbid; So-called " pondering over the tired heart that decreases at most " (" General Treatise on the Cause and Symptoms of Diseases obstruction of heart-QI time "), " shake of the heart resulting from excessive sorrow and melancholy " (" the Ling Shu Miraculous Pivot or Divine Axis mouth is asked ").The then look hypertonicity of being worried in terror, insufficiency of heart-QI is timid, and cloudy blood secretly consumes, can not nourish heart, rage impairing liver, large excessive fear impairing the kidney, anger is QI rising in reverse order then, and probably then essence is but; Exopathogen is assorted extremely, close and be numbness, arthromyodynia with the passing of time, the interior house in the heart, evil resistance heart arteries and veins, painstaking effort battalion row causes " irregularly intermittent and regularly intermittent pulse, severe palpitation " class syndrome, is to be syndrome of disharmony between heart and kidney.  
Chinese medicine is being brought into play unique advantage aspect the treatment disarmony between the heart and kidney, such as " Yifangleiju " record " heart kidney ball: Radix Achyranthis Bidentatae, Radix Rehmanniae Preparata, each 60 gram of Herba Cistanches, Cornu Cervi Pantotrichum, Radix Aconiti Lateralis Preparata, Fructus Schisandrae Chinensis, Radix Ginseng, Radix Polygalae, Radix Angelicae Sinensis, each 30 gram of Os Draconis, Semen Cuscutae 90 grams "; " Fructus Pruni garden " then carries heart kidney ball: " Semen Ziziphi Spinosae, Fructus Alpiniae Oxyphyllae, Concha Ostreae, each 50 gram of Radix Ginseng, Poria, each 100 gram of Fructus Psoraleae, Fructus Anisi Stellati 25 grams, the Rhizoma Atractylodis Macrocephalae 150 grams ".Clinical proof, this prescription has obvious therapeutic effect to disarmony between the heart and kidney.
But the raising along with people's living standard, the change of dietary structure, social development rhythm is accelerated day by day, the clinical symptoms showed increased such as the rheumatic heart disease that is caused by disarmony between the heart and kidney in recent years, coronary heart disease, myocardial ischemia, cerebral blood supply insufficiency, arrhythmia, heart failure, tachycardia, angina pectoris, arteriosclerosis, diabetes.Chinese medicine " heart kidney ball " has presented wretched insufficiency on therapeutic effect, and doctor trained in Western medicine is clinically usually according to facing disease treatment, headache doctor head, and repeatedly outbreak has strengthened medical treatment cost, can not give thorough treatment from Etiologic Mechanism.
Summary of the invention
The objective of the invention is the achievement in research by modern pharmacology, a kind of one-tenth side's Chinese medicine composition that is suitable for treating dissimilar syndrome of disharmony between heart and kidney, cardiovascular and cerebrovascular disease is provided, to reach activating QI to alleviate the depression, benefiting essence and marrow, benefiting QI and nourishing blood, nourishing kidney yin, the fire of balance three warmers, kidney Waterborne running then makes that heart-fire descends, logical heart kidney and reach the purpose of coordination between the heart and kidney.
For reaching above-mentioned technical purpose, the technical solution used in the present invention is: a kind of Chinese medicine composition for the treatment of the cardiovascular and cerebrovascular disease that disarmony between the heart and kidney causes, it is characterized in that, described Chinese medicine composition contains the material medicine of following weight proportion: Cor Cervi 8-12, Radix Cynanchi Auriculati 3-5, Radix Polygalae 10-30, Radix Angelicae Sinensis 10-35, Poria 10-30, Radix Salviae Miltiorrhizae 10-20.
Also contain one or more the drug regimen in the material medicine of following weight proportion in the above-mentioned Chinese medicine composition: Pulveratum Cornu Cervi Pantotrichum 3-5, Rhizoma Chuanxiong (processing) 20-30, succinum 10-20, Radix Asparagi 10-20, Radix Ginseng Rubra 10-30, Herba Epimedii 10-30, the Radix Astragali (processing) 20-30, Semen Ziziphi Spinosae 40-80, Bai Ren 10-20, Cinnabaris 10-15, Os Draconis 10-40, Cortex Cinnamomi 10-15, Fructus Schisandrae Chinensis 10-20, Radix Glycyrrhizae (processing) 10-20.
Chinese medicine composition provided by the invention has the effect of activating QI to alleviate the depression, balance three warmers, benefiting essence and marrow.Get in the material medicine Cor Cervi, Radix Cynanchi Auriculati, Radix Polygalae, Radix Angelicae Sinensis, Poria, Radix Salviae Miltiorrhizae invigorate blood circulation sensible, blood-activating analgetic, the merit of the Fructus Alpiniae Oxyphyllae of calming the nerves reaches the expansion peripheral blood vessel, improves microcirculation, strengthens the effect of immunologic function, so be to be monarch drug; Get Cornu Cervi Pantotrichum, Herba Epimedii, Semen Ziziphi Spinosae, Bai Ren, Cinnabaris, Radix Ginseng Rubra, Os Draconis, Radix Rehmanniae Preparata, Herba Cistanches, succinum, Radix Asparagi, Fructus Schisandrae Chinensis, the Rhizoma Atractylodis Macrocephalae, the logical heart kidney of Fructus Alpiniae Oxyphyllae, benefiting essence and marrow, benefiting QI and nourishing blood, nourishing the liver and kidney, strong activating the spleen lung, the merit of rapid digestion of food and polyorexia, short coordination between the heart and kidney, priming is descending, is adjuvant drug altogether; Get Rhizoma Chuanxiong, Chinese Angelica blood replonishing is invigorated blood circulation, the Cortex Cinnamomi promoting the flow of QI-blood by warming the meridian; The Fructus Schisandrae Chinensis convergence is astringent or styptic treatment for spontaneous sweating, is adjuvant drug altogether.Extracting liquorice is in harmonious proportion the property of medicine for making medicine.Above-mentioned all medicine phases 5, Each performs its own functions, play altogether eliminate uncomfortable in chest, breathe hard, have palpitation, the effect of weak, cardiopalmus, insomnia, dizziness, the clinical symptoms such as suffer from a deficiency of the kidney, and then reach treatment because of clinical diseases such as the rheumatic heart disease of disarmony between the heart and kidney initiation, coronary heart disease, myocardial ischemia, cerebral blood supply insufficiency, arrhythmia, heart failure, tachycardia, angina pectoris, arteriosclerosis.
Old heart infarction, type Ⅱdiabetes mellitus, the hypertension complication that brings out because of disarmony between the heart and kidney also there are good treatment, reparation, rehabilitation efficacy.
Its processing technology is as follows:
1, selects materials: choose Cervus nippon Temminck with the fresh or dry heart of blood.
2, infusion: the Cor Cervi process of preparing Chinese medicine of should going ahead of the rest, use the flushing with clean water surface contaminants, drying.Time spent is cut into small pieces, and smashs to pieces or pulverizes.
3, Chinese medicine processing: raw material of Chinese medicine is carried out compatibility, scorch, pulverize, sieve, the operation such as mixing.
4, general ball, drying, sterilization: select pure honey, add the general ball of making of Chinese medicine powder, drying sterilizing after the honey refining.
Chinese medicine composition provided by the present invention can adopt following manner to take:
Described Chinese prescription, the inconvenience of bringing in decoction process for overcoming Chinese medicine is convenient to take, and this Chinese medicine is traditional pill.
Function: vigorate qi and replenish the blood, the heart tonifying that nourishes heart, tranquilizing the mind, it is sensible to invigorate blood circulation, YIN nourishing and YANG strengthening, blood-activating analgetic.
Adapt to symptom: be used for dizziness and tinnitus due to the cardiovascular and cerebrovascular vessel blood supply insufficiency; Palpitation and insomnia due to the disarmony between the heart and kidney, god is forgetful all of a sudden, fluctuation of blood pressure, excessive thirst polydipsia, polyorexia, soreness of the waist and knees, urinary micturition, constipation, dry mouth and throat, blurred vision, sensation of oppression over the chest with shortness of breath, being happy and angry uncertainly, the fear of cold sexual impotence, edema over the face is weak, and is how moving few quiet, katzeniammer, mouth has abnormal flavour etc.
The hypertension of bringing out because of disarmony between the heart and kidney, hyperlipidemia, diabetes (II type), rheumatic heart disease, coronary heart diseases and angina pectoris, heart failure, myocardial ischemia, cerebral infarction, apoplexy, parkinson, old heart infarction etc. also there are good therapeutic effect and preventive effect.
Clinical practice: each 1 ball after ante cibum morning every day, the supper, 15 is a course for the treatment of, serve on 2-3 the course for the treatment of; Add and subtract with disease: can be adjusted to each 12-15g by symptom, note psychological counseling in the time of Drug therapy and take good care of.
The taboo item: raw meat, peppery, Radix Raphani, tea, cigarette, wine etc., or follow the doctor's advice and withdraw other medicines.
Below by concrete case the clinical effectiveness that Chinese medicine composition provided by the invention reaches is described further.
Medical record 1
Mr. Li, nineteen sixty gives birth to, top managers, patient's private prosecution: its father, uncle respectively at soldier over fifty years old in heart disease; Often dizzy weak, the long-term insomnia of patient, abdominal distention uncomfortable in chest, mood is gloomy, absentminded, hypomnesis; Body constitution is irritated, the appetite extreme difference.
Lab testing: ultrasonic cardiography shows coronary stricture, blood pressure: 140/80mmHg, urine protein +++, twenty-four-hour urine protein quantification 4.8g, blood urea nitrogen 6.50mmol/L, serum creatinine 180 μ mmol/l, T-CHOL 7.60mmol/l, fasting glucose 8.7mmol/L, total serum protein 70.4mmol/L, albumin 40.2mmol/L.
Tcm diagnosis is syndrome of disharmony between heart and kidney, type Ⅱdiabetes mellitus complication with diabetes nephropathy.Distinguish to be deficiency of both YIN and YANG the syndrome of blood stasis due to qi deficiency of holding concurrently.
Bypass surgery is done in the doctor trained in Western medicine suggestion, is aided with Drug therapy.
Etiological analysis: the numerous and diverse and competitive pressure of public affair and losing one's father when still a small child, spirit is among the nervous anxiety for a long time, and life lacks rule, and sleep is few, temperament and interest pent-up, stagnated QI transforming into fire, deficiency of kidney-YIN, flaming up of heart-fire involves healthy energy, and card belongs to disarmony between the heart and kidney.
Clinical treatment: intend the kidney warming QI invigorating, YIN nourishing blood stasis dispelling, inducing diuresis to remove edema.Amount to four courses for the treatment of through taking the pill that this prescription concocts: 15 days first courses for the treatment of, every days two ball, every ball 10 grams, the patient feels well, spirit and QI cleaning; Appetite increases, and sleeps.Add 5 grams second and third course for the treatment of, curative effect is obvious at every turn; The 4th course for the treatment of, change each 10 grams into, to consolidate curative effect.
Efficacy analysis: the patient feels good; TCM pulse diagnosis is heavy thin strong, and clinical symptoms is eliminated; Laboratory check indices also is improved greatly, and it is very good to produce effects.
Medical record 2
Mr. Sun, 23 years old, main symptom: palpitation and restlessness, dizziness and tinnitus, soreness of the loins and nocturnal emission, myasthenia of limbs, vexed dreaminess, night, difficulty was fallen asleep, poor memory, dry mouth and lack of saliva, red tongue, thready and rapid pulse.
Etiological analysis and differentiation: kidney yin damage loss, can not on give in the heart, due to the discordance between water(the kidney)and fire(the heart), asthenic fire disturbing the mind upwards.
Clinical treatment: YIN nourishing clears away heart-fire, the Fructus Alpiniae Oxyphyllae of calming the nerves, restoring normal coordination between the heart and kidney.Take the pill that this prescription is concocted, after two courses for the treatment of, it is as usual that spirit is just recovered, and all symptoms also thoroughly disappear.
Above-mentioned Chinese medicine composition meets the syndrome of disharmony between heart and kidney diagnostic criteria to 32 examples, and the age is carried out clinical research 20-80 years old patient, and 15 days is a course for the treatment of; 16 examples such as palpitation and insomnia nocturnal emission wherein, old heart infarction 3 examples, hypertension, hyperlipidemia, diabetes (II type) complication 6 examples, coronary heart disease, rheumatic heart disease 4 examples, other pattern of syndrome 3 examples.
All hepatic and kidney function obstacle persons do not include research in, will observe the symptoms in detail in the research, sign changes and have or not adverse effect, before and after the medication 10 days and finish the course for the treatment of after carry out routine examination, the standard of curative effect evaluation is by produce effects, the evaluation of effective, invalid three classes.
By statistics, take effective 29 examples of clinical treatment that this Chinese medicine composition causes the treatment syndrome of disharmony between heart and kidney, produce effects 27 examples, invalid 3 examples, by statistics, effective percentage is 90.6%, the untoward reaction record that causes because taking medicine does not appear in obvious effective rate 84.3%.
The specific embodiment
Embodiment 1
A kind of Chinese medicine composition for the treatment of the cardiovascular and cerebrovascular disease that disarmony between the heart and kidney causes is characterized in that described Chinese medicine composition contains the material medicine of following weight proportion: Cor Cervi 8g, Radix Cynanchi Auriculati 5g, Radix Polygalae 10g, Radix Angelicae Sinensis 35g, Poria 10g, Radix Salviae Miltiorrhizae 20g, Pulveratum Cornu Cervi Pantotrichum 3g, succinum 20g, Radix Asparagi 10g, Radix Ginseng Rubra 30g, Semen Ziziphi Spinosae 40g, Bai Ren 20g, Cinnabaris 10g, Cortex Cinnamomi 15g, Fructus Schisandrae Chinensis 10g.
Embodiment 2
A kind of Chinese medicine composition for the treatment of the cardiovascular and cerebrovascular disease that disarmony between the heart and kidney causes is characterized in that described Chinese medicine composition contains the material medicine of following weight proportion: Cor Cervi 12g, Radix Cynanchi Auriculati 3g, Radix Polygalae 30g, Radix Angelicae Sinensis 10g, Poria 30g, Radix Salviae Miltiorrhizae 10g, Pulveratum Cornu Cervi Pantotrichum 5g, Rhizoma Chuanxiong (processing) 20g, succinum 10-20, Herba Epimedii 10g, the Radix Astragali (processing) 30g, Os Draconis 10g, Cortex Cinnamomi 10g, Fructus Schisandrae Chinensis 20g, Radix Glycyrrhizae (processing) 10g.
Embodiment 3
A kind of Chinese medicine composition for the treatment of the cardiovascular and cerebrovascular disease that disarmony between the heart and kidney causes is characterized in that described Chinese medicine composition contains the material medicine of following weight proportion: Cor Cervi 10g, Radix Cynanchi Auriculati 4g, Radix Polygalae 20g, Radix Angelicae Sinensis 25g, Poria 20g, Radix Salviae Miltiorrhizae 15g, Pulveratum Cornu Cervi Pantotrichum 4g, Rhizoma Chuanxiong (processing) 30g, succinum 15g, Radix Asparagi 20g, Radix Ginseng Rubra 10g, Herba Epimedii 30g, the Radix Astragali (processing) 20g, Semen Ziziphi Spinosae 80g, Bai Ren 10g, Cinnabaris 15g, Os Draconis 40g, Cortex Cinnamomi 15g, Fructus Schisandrae Chinensis 15g, Radix Glycyrrhizae (processing) 20g.
Embodiment 4
A kind of Chinese medicine composition for the treatment of the cardiovascular and cerebrovascular disease that disarmony between the heart and kidney causes is characterized in that described Chinese medicine composition contains the material medicine of following weight proportion: Cor Cervi 9g, Radix Cynanchi Auriculati 5g, Radix Polygalae 10g, Radix Angelicae Sinensis 25g, Poria 18g, Radix Salviae Miltiorrhizae 18g, Rhizoma Chuanxiong (processing) 26g, Herba Epimedii 15g, the Radix Astragali (processing) 22g, Os Draconis 15g, Radix Glycyrrhizae (processing) 15g.
  

Claims (2)

1. a Chinese medicine composition for the treatment of the cardiovascular and cerebrovascular disease that disarmony between the heart and kidney causes is characterized in that described Chinese medicine composition contains the material medicine of following weight proportion: Cor Cervi 8-12, Radix Cynanchi Auriculati 3-5, Radix Polygalae 10-30, Radix Angelicae Sinensis 10-35, Poria 10-30, Radix Salviae Miltiorrhizae 10-20.
2. a kind of Chinese medicine composition for the treatment of the cardiovascular and cerebrovascular disease that disarmony between the heart and kidney causes according to claim 1, it is characterized in that: also contain one or more the drug regimen in the material medicine of following weight proportion in the above-mentioned Chinese medicine composition: Pulveratum Cornu Cervi Pantotrichum 3-5, Rhizoma Chuanxiong (processing) 20-30, succinum 10-20, Radix Asparagi 10-20, Radix Ginseng Rubra 10-30, Herba Epimedii 10-30, the Radix Astragali (processing) 20-30, Semen Ziziphi Spinosae 40-80, Bai Ren 10-20, Cinnabaris 10-15, Os Draconis 10-40, Cortex Cinnamomi 10-15, Fructus Schisandrae Chinensis 10-20, Radix Glycyrrhizae (processing) 10-20.
CN201310282554.0A 2013-07-08 2013-07-08 Chinese medicinal composition treating cardiovascular and cerebrovascular diseases caused by heart-kidney imbalance Expired - Fee Related CN103372135B (en)

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103961531A (en) * 2014-05-29 2014-08-06 济南伟传信息技术有限公司 Traditional Chinese medicine for treating palpitation
CN104435865B (en) * 2014-12-29 2015-05-13 尹忠民 Traditional Chinese medicine for treating arrhythmia and preparation method thereof
CN104721489A (en) * 2015-03-24 2015-06-24 侯荣耀 Chinese patent medicine for treating Parkinson disease and preparation method thereof
CN105232646A (en) * 2015-11-16 2016-01-13 杨全江 Traditional Chinese medicine acupuncture point external medicine bag for treating cardiovascular and cerebrovascular diseases and preparation method thereof
CN105688068A (en) * 2016-03-20 2016-06-22 邱文辉 Chinese herbal preparation for treating arrhythmia and preparing method of Chinese herbal preparation
CN107596291A (en) * 2017-08-11 2018-01-19 孟广千 With the Chinese medicine composition of tonifying liver side's treatment heart asthenic symptoms disease

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
袁颖: "《"交通心肾" 方药略议》", 《时珍国医国药》 *

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103961531A (en) * 2014-05-29 2014-08-06 济南伟传信息技术有限公司 Traditional Chinese medicine for treating palpitation
CN104435865B (en) * 2014-12-29 2015-05-13 尹忠民 Traditional Chinese medicine for treating arrhythmia and preparation method thereof
CN104721489A (en) * 2015-03-24 2015-06-24 侯荣耀 Chinese patent medicine for treating Parkinson disease and preparation method thereof
CN105232646A (en) * 2015-11-16 2016-01-13 杨全江 Traditional Chinese medicine acupuncture point external medicine bag for treating cardiovascular and cerebrovascular diseases and preparation method thereof
CN105232646B (en) * 2015-11-16 2019-02-26 杨全江 A kind of traditional Chinese medicine acupoint external application pack that treating cardiovascular and cerebrovascular disease and preparation method
CN105688068A (en) * 2016-03-20 2016-06-22 邱文辉 Chinese herbal preparation for treating arrhythmia and preparing method of Chinese herbal preparation
CN107596291A (en) * 2017-08-11 2018-01-19 孟广千 With the Chinese medicine composition of tonifying liver side's treatment heart asthenic symptoms disease

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