CN103371865B - Cold brine perfusion type radiofrequency ablation catheter - Google Patents
Cold brine perfusion type radiofrequency ablation catheter Download PDFInfo
- Publication number
- CN103371865B CN103371865B CN201310093644.5A CN201310093644A CN103371865B CN 103371865 B CN103371865 B CN 103371865B CN 201310093644 A CN201310093644 A CN 201310093644A CN 103371865 B CN103371865 B CN 103371865B
- Authority
- CN
- China
- Prior art keywords
- transfer passage
- fill orifice
- ablating electrode
- ablation catheter
- curved segment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Abstract
The invention provides a cold brine perfusion type radiofrequency ablation catheter which comprises a catheter body, a control handle, an ablation electrode, brine delivery passages and perfusion holes. The catheter body comprises a main section and a bendable section for entering the body of a patient, the control handle is used for bending the bendable section, the ablation electrode is arranged at a far end of the bendable section, the brine delivery passages are used for delivering cold brine, the perfusion holes are connected to the corresponding delivery passages and used for perfusing the cold brine to the ablation electrode and a target site. The cold brine perfusion type radiofrequency ablation catheter is characterized in that the catheter comprises more than two delivery passages, and each delivery passage corresponds to at least one perfusion hole.
Description
This application claims applicant and be 201210108727.2 and title is the priority that " cold brine infusion type radiofrequency ablation catheter " applies in the application number that on April 13rd, 2012 submits to.
Technical field
The present invention relates to a kind of radio frequency ablation catheter.More specifically, the present invention relates to a kind of cold brine infusion type radiofrequency ablation catheter.
Background technology
Radio frequency ablation catheter is the one of electrophysiologicalcatheter catheter, is mainly used in operation on heart, also starts in recent years to be applied to hypertensive treatment.
In operation, radio frequency ablation catheter percutaneous puncture is transported to the target site that pathological changes occurs, and the dispersing electrode of the ablating electrode and patient back that are now positioned at distal end of catheter forms loop.By ablating electrode by the transmission of radio-frequency energy of launching to the pathological tissues near it, make it dewater to solidify to lose conductivity function, thus realize treatment tachyarrhythmia or treat the objects such as hypertension.
Traditional ablating electrode, in order to reach darker depth of ablation, can use higher ablation energy clinically, easy in like this target site surface formation localized hyperthermia, easily facilitate thrombosis, eschar, thus affect safety and effectiveness, extend operating time, increase the misery of patient.
In order to darker depth of ablation can be reached, can while radio-frequency (RF) ablation, cool brine is sprayed equably around radio-frequency ablation electrode, the temperature of radio-frequency ablation electrode is alleviated while the depth of ablation that ablation catheter can be made like this to utilize higher power to reach darker, thus while guarantee therapeutic effect, can also prevent target site surface from forming localized hyperthermia, reduce incrustation and thrombosed probability, improve safety and the effectiveness of operation.
Current cold brine infusion type radiofrequency ablation catheter adopts a main cool brine transfer passage usually, and ablating electrode distributes the design of multiple perfusion channel.Because the perfusion channel of shunting is shorter, blood etc. easily enter into main transfer passage via perfusion channel, as long as this unique transfer passage blocks, will cause thorough blocking, lose cool brine conveying and perfusion ability.
Authorization Notice No. is that the utility model patent of CN 201453373 discloses a kind of rf ablation therapeutic instrument that automatically can control cold brine perfusion, comprise radiofrequency ablation therapy device, cold brine perfusion pump, cold brine perfusion conduit etc., by a quad, radiofrequency ablation therapy device is connected with cold brine perfusion pump.This utility model patent is pointed out: during without cold brine perfusion, and the temperature of conduit head end can reach 62 DEG C, and when adding cold brine perfusion, the temperature of conduit head end drops to 42 DEG C, greatly reduces the risk of incrustation or formation thromboembolism, adds the safety of operation.This utility model patent proposes the thinking of cold brine perfusion, but does not point out the concrete structure of cold brine infusion type radiofrequency ablation catheter.
Authorization Notice No. is the electrode that the utility model patent of CN 201244080 discloses that a kind of cool brine rinses radio frequency ablation catheter, on the cylindric body of cool brine flushing radio frequency ablation catheter electrode, four grooves are respectively opened as cool brine irrigation channel in the position of the quartering, it is characterized in that: head end is cross section, make 4 cool brine apopores be positioned at the groove of electrode tip proximal lateral, rinse along the longitudinal axis.This utility model patent only mentions the design of electrode tip, does not introduce the design of other dependency structures of cold brine infusion type radiofrequency ablation catheter.
The patent No. is in the United States Patent (USP) of US 6171275, proposes one and " has the electrode catheter (Irrigated split tip electrode catheter) of perfusing hole at far-end ".By being arranged on the fill orifice of ablating electrode far-end, in the ablation procedure of operation, pour into a certain amount of physiology cool brine.Cool brine can be cooled ablating electrode and pathological tissues surface when being flowed out by the opening on ablating electrode, so just can avoid surface incrustation while guaranteeing deeply to melt the degree of depth, thus improves effectiveness and the safety of operation.But this design also defectiveness, in ablative surgery, ablating electrode is likely close to diseased region inwall with its side or far-end.In this case, cardiac muscular tissue is melted, radio-frequency (RF) energy is launched by ablating electrode and thermal dehydration solidifies, but because fill orifice is positioned at the far-end of ablating electrode, and only have a cool brine transfer passage, therefore fill orifice and transfer passage are all easy to block, and cause occurring hot-spot and causing incrustation.
Authorization Notice No. is the cold brine infusion type radiofrequency ablation catheter that the utility model patent of CN201356648 discloses a kind of improvement, and this radio frequency ablation catheter has two irrigation and drainage orifices, greatly can improve the safety and reliability of radio-frequency (RF) ablation.Although this utility model patent is provided with multiple fill orifice, cool brine transfer passage is only one, same easily there is transfer passage blocking and cause and thoroughly lose perfusion functional.
The invention provides a kind of cold brine infusion type radiofrequency ablation catheter, wherein, cool brine adopts many transfer passages to be transported to multiple fill orifices of radio frequency ablation catheter, cool brine is transported to therapeutic target position along many paths, can ensure that radio-frequency ablation electrode has lower temperature while having higher-wattage, realize the degree of depth to melt, improve the safety and reliability of radio-frequency (RF) ablation simultaneously.Even if wherein a certain carrying path blocks, do not affect other carrying paths conveying cool brine yet, thus more guarantee the safety and reliability of operation.The present invention can be used as the radio frequency ablation catheter of the diseases such as treatment arrhythmia, also can be used as renal artery denervation and treat hypertensive radio frequency ablation catheter.In addition, guide-tube structure of the present invention is simple, is conducive to cost-saving.
Summary of the invention
The object of the invention is to the defect of the cold brine infusion type radiofrequency ablation catheter overcoming single carrying path, even if a certain carrying path blocks, residue carrying path still can be used in carrying cool brine, and by enough cold brine perfusions to ablating electrode and target site, thus avoid causing target site tissue to form a scab because of hot-spot.
The invention provides a kind of cold brine infusion type radiofrequency ablation catheter, it comprises: conduit pipe shaft, and described conduit pipe shaft comprises for entering main paragraph in patient body and can curved segment; Joystick, described joystick is for realize can curved segment bending; Ablating electrode, described ablating electrode is arranged on can on curved segment far-end; Saline transfer passage, described saline transfer passage is for carrying cool brine; And fill orifice, described fill orifice is for being connected to corresponding transfer passage and by cold brine perfusion to ablating electrode and target site; It is characterized in that, described transfer passage is two or more, and each transfer passage is corresponding with at least one fill orifice.Preferably, each transfer passage is corresponding with plural fill orifice, and the number of fill orifice is more than 2.Transfer passage due to cool brine is two or more, can reduce blocked risk.
Preferably, fill orifice be arranged on can in curved segment with the proximal edge of ablating electrode at a distance of 0-5mm place, to obtain the effective cooling effect of ablating electrode.More preferably, fill orifice be arranged on can in curved segment with the proximal edge of ablating electrode at a distance of 0-3mm place.Preferably, the perforate direction of fill orifice becomes to be less than or equal to the angle of 90 degree with the direction of principal axis distad of ablating electrode, thus makes the cool brine flowed out from fill orifice smooth-goingly can flow to ablating electrode, is conducive to the cooling effect making full use of cool brine.Preferably, the number of fill orifice is more than 2.Preferably, the number of fill orifice is 2-9.Preferably, fill orifice being circumferentially uniformly distributed at conduit, to obtain uniform perfusion, is conducive to, when the different piece of conduit reclines target site tissue, all can obtaining effective cool brine flow, reduces the risk of all blockings further.
Fill orifice also can be arranged on ablating electrode, thus obtain the more effective cooling of ablating electrode and simplifying catheter can the structure of curved segment.Wherein on ablating electrode, the number of fill orifice is more than 2, and preferably, on ablating electrode, the number of fill orifice is 2-9.Preferably, on ablating electrode, fill orifice can be evenly distributed on one circumferentially, also can be evenly distributed on circumferentially several, with obtain circumferentially with longitudinally evenly irrigation flow, and be conducive to, when the different piece of ablating electrode reclines target site tissue, all can obtaining effective cool brine flow.
When fill orifice is 2-3, fill orifice avoids being arranged on ablating electrode or conduit relative to the place that reclines of target site tissue, hinders cool brine to flow out to avoid reclining when target site is organized.
Preferably, fill orifice is connected with transfer passage via shunting perfusion channel.According to the demand of clinical ablation effect to cold brine perfusion flow, the scope of fill orifice and shunting perfusion channel diameter is advisable at 0.05-0.6mm, and transfer passage diameter is advisable at 0.3-1.5mm.Fill orifice can be holed realization on ablating electrode, also can, by machinery or hot mode perforate on the tube wall of conduit, preferably adopt laser punching mode to realize.In addition, transfer passage can require to adopt multistage to be formed by connecting according to guide-tube structure, and wherein the main paragraph part of transfer passage can adopt the high-strength thin-walled tubing of the hard such as polyimides to make, and takes up room to reduce tube wall, expands intracavity diameter.Cool brine transfer passage can be formed vertically on ablating electrode, and be connected and sealed with the transfer passage in conduit pipe shaft.
When arranging fill orifice on the tube wall of conduit: by thermally coupled or glue bonding mode transfer passage can be sealably coupled to the fill orifice on tube wall; Also can by the main paragraph part of transfer passage and utilizing be used as can curved segment part can being connected and forming described transfer passage of the transfer passage section that formed of the tract of multi-lumen tube of curved segment, and on described tract wall with the suitable distance place perforate apart of the proximal edge of ablating electrode to form fill orifice.As required, multi-lumen tube can be selected from three lumens, four lumens, five-tubed catheter or six lumens.The different sections of conduit can be selected from dissimilar multi-lumen tube.In addition, by other additional thinner tubular materials in multi-lumen tube, multichannel can also be realized at same intracavity.
Preferably, ablating electrode can be made up of platinumiridio, gold, rustless steel or nickel alloy.
Accompanying drawing explanation
In order to more clearly describe technical scheme of the present invention, briefly introduce below in conjunction with accompanying drawing.Obviously, these accompanying drawings are only some detailed description of the invention that the application records.Technical scheme according to the present invention includes but not limited to these accompanying drawings following.
Fig. 1 illustrates the integrally-built schematic diagram of cold brine infusion type radiofrequency ablation catheter.
Fig. 2 illustrates the localized axial profile of cold brine infusion type radiofrequency ablation catheter according to an embodiment of the invention, wherein, the catheter wall near ablating electrode arranges fill orifice.
Fig. 3 a and Fig. 3 b illustrates the localized axial profile of cold brine infusion type radiofrequency ablation catheter according to another embodiment of the present invention and the radial section figure on sagittal plane, place, fill orifice center respectively, wherein, ablating electrode arranges fill orifice.
Fig. 4 a is the localized axial profile of the cold brine infusion type radiofrequency ablation catheter illustrated according to further embodiment of this invention, wherein, the axially different position of ablating electrode arranges two groups of fill orifices 9, and Fig. 4 b and Fig. 4 c illustrates the radial section figure on sagittal plane, place, each group of fill orifice center respectively.
Fig. 5 a and 5b illustrates two kinds of exemplary arrangement modes of two groups of fill orifices on ablating electrode respectively.
Fig. 6 a and 6b illustrates respectively when the mode of blood vessel wall of reclining with upper wall is applied according to the schematic diagram of cold brine infusion type radiofrequency ablation catheter of the present invention and the view in transverse section that intercepts along line II-II.
Fig. 7 a and 7b illustrates respectively when the mode of blood vessel wall of reclining with lower wall is applied according to the schematic diagram of cold brine infusion type radiofrequency ablation catheter of the present invention and the view in transverse section that intercepts along line III-III.
The explanation of Reference numeral
1 saline connects female Luer; 2 saline connection tubes; 3 receptacles; 4 joysticks; 5 main paragraphs; 6 can curved segment; 7 transfer passages can curved segment part; 8 ablating electrode 9 fill orifices; 10 bracing wires;
A cool brine transfer passage; B/C cool brine shunting perfusion channel; RP sympathetic nerve
Detailed description of the invention
In order to understand the present invention further, below in conjunction with embodiment, preferred version of the present invention is described.These descriptions just illustrate the features and advantages of the present invention, but not limit the scope of the invention.
Fig. 1 illustrates the integrally-built schematic diagram of cold brine infusion type radiofrequency ablation catheter.Described cold brine infusion type radiofrequency ablation catheter comprises: conduit pipe shaft, comprises for entering main paragraph in patient body 5 and can curved segment 6; For realize can the bending joystick 4 of curved segment 6; Being arranged on can ablating electrode 8 on curved segment 6 far-end; The transfer passage 7 for carrying cool brine in conduit; For being connected to described transfer passage 7 and by cold brine perfusion to the fill orifice 9 on ablating electrode 8 and target site.
Usually be provided with in joystick 4 for bracing wire 10(in A/C see Fig. 4 and Fig. 5) and control the frame for movement of its movement, so that can bending relative to main paragraph 5 of curved segment 6 via controlling that the movement of bracing wire 10 adjusts, joystick outward appearance and size meet and grip comfortableness demand.This give through bracing wire move control can the bending a kind of frame for movement of curved segment 6 exemplarily, other frame for movements also go for joystick 4.
The length of main paragraph 5 is 90cm, tinsel reinforced pipe is adopted to make, caliber is 6F(2mm), the main paragraph 5 of conduit is embedded with the parts such as wire, two-way cool brine transfer passage pipe (the main paragraph part also referred to as transfer passage), bracing wire, and wherein bracing wire does not show in the drawings.The main paragraph part of transfer passage can adopt the high-strength thin-walled tubing of the hard such as polyimides to make, and takes up room to reduce tube wall, expands intracavity diameter.
Can the length of curved segment 6 be 5cm, medium-hard four lumen materials are used to prepare, its near-end is connected by thermal weld with main paragraph 5, can cool brine transfer passage 7(in curved segment 6 also referred to as transfer passage can curved segment part) comprise two-way, utilize preparation can realize in two relative chambeies in four lumens of curved segment 7, internal diameter is 0.3-1.5mm, preferred 0.4mm.In the present embodiment, the cool brine transfer passage on each road is totally by by its main paragraph part with each road of curved segment part can be connected and sealed respectively and keep that inner chamber is unobstructed to be obtained, and this is as just example.Cool brine transfer passage also can be made into integration with polyimides, and is embedded in main paragraph 5 and can in curved segment 6, for transporting the cool brine from outside cool brine source to fill orifice 9.In the present embodiment, show two-way cool brine transfer passage, but cool brine transfer passage can be two or more.
On the wall that can be used as two chambeies of cool brine transfer passage in curved segment 6 with the proximal edge of ablating electrode 8 at a distance of 0-5mm place, preferred 0-3mm place, with heating large vent needle or carrying out oblique perforate respectively via laser cutting parameter, forms two fill orifices 9.For the integrated cool brine transfer passage in each road, then can in curved segment with the proximal edge of ablating electrode 8 at a distance of 0-5mm place, preferred 0-3mm place, forms two fill orifices 9 in the same way, and is sealably coupled to corresponding each road cool brine transfer passage.Although in the present embodiment, each transfer passage is corresponding with a fill orifice, and preferred each transfer passage is corresponding with plural fill orifice, to recline the risk causing when target site is organized blocking to reduce catheter wall.
Exemplarily, the main paragraph part 7 of cool brine transfer passage can be connected female Luer 1(standard component by saline connection tube 2 with saline) be connected to cool brine source, to transport the cool brine of self cooling saline source.The length that saline connection tube 2 exposes joystick 4 is 5cm, other parts are then connected with the main paragraph part 7 of two-way cool brine transfer passage in joystick 4, make the inner chamber of the main paragraph part 7 of the inner chamber of saline connection tube 2 and two-way cool brine transfer passage unobstructed, and ensure that junction sealing (can seal with epoxies glue) is reliable.The quick plug receptacle that receptacle 3 is connected with radiofrequency melting instrument electrical equipment for realizing conduit, carries out with coordinating of ablation operation to realize cold brine perfusion flushing cooling.
Fig. 2 illustrates the localized axial profile of cold brine infusion type radiofrequency ablation catheter according to an embodiment of the invention, wherein, the conduit near ablating electrode the wall of curved segment can arrange fill orifice.Similar to the above embodiments, form can the chamber of multi-lumen tube of curved segment be used as cool brine transfer passage can curved segment part, form fill orifice 9 in the hot perforate of chamber wall surface thereof, the center of fill orifice 9 and the proximal edge of ablating electrode 8 distance are apart 0.5mm.In actual use, cool brine transfer passage A can be connected to fill orifice 9 by shunting perfusion channel B, that is, out namely flows to ablating electrode and melt target direction after cool brine enters shunting perfusion channel B by cool brine transfer passage A from fill orifice 9.
The perforate direction of fill orifice becomes to be less than the angle of 90 degree with the axis distad of ablating electrode 8, cool brine is made more smoothly to flow to ablating electrode, to realize effective cooling effect, can effectively reduce ablating electrode, melt the temperature of target and contiguous blood, thus raising ablation power, obtain darker ablation effect, and prevention incrustation, improve operation safety and reliability.This angle is preferably 10-60 degree, is more preferably 30 degree.The advantage of this embodiment is that fill orifice 9 is arranged in curved segment, can avoiding the ablating electrode using labyrinth, being conducive to reducing costs of conduit.
Fig. 3 a and Fig. 3 b illustrates the localized axial profile of cold brine infusion type radiofrequency ablation catheter according to another embodiment of the present invention and the radial section figure on sagittal plane, place, fill orifice center respectively, wherein, ablating electrode arranges fill orifice.Ablating electrode is provided with the two-way cool brine transfer passage A corresponding with the main paragraph part of two-way cool brine transfer passage.At the distal tip place of this two-way cool brine transfer passage A, in ablating electrode, offer 6 shunting perfusion channel B along direction perpendicular to axial direction, form 6 fill orifices 9.It is corresponding that each cool brine transfer passage A shunts perfusion channel B with 3 respectively.Cool brine transfer passage on ablating electrode and shunting perfusion channel all can adopt direct mechanical processing punching on ablating electrode to obtain.Can being connected and sealed and keeping inner chamber unobstructed by the cool brine transfer passage A on curved segment part and ablating electrode of cool brine transfer passage.Cool brine transfer passage A diameter on ablating electrode is chosen as suitable in the scope of 0.3-1.5mm, is preferably 0.5mm, and the diameter of 6 shunting perfusion channel B and fill orifice 9 is then chosen as suitable in the scope of 0.05-0.6mm, is preferably 0.3mm.The length of each shunting perfusion channel is suitable, to ensure that its pressure differential is suitable, thus obtains uniform perfusion.The present embodiment is by opening on ablating electrode by fill orifice, and cool brine acts on surface and the inside of ablating electrode, can obtain the more effective cooling effect to ablating electrode; And realize the design of six fill orifices by two carrying paths, can simplifying catheter can the structure of curved segment, conveniently to manufacture; Six fill orifices can improve the uniformity of perfusion and the risk of the whole blocking of minimizing further simultaneously, improve the safety of operation.
Fig. 2 and Fig. 3 a and the fill orifice shown in Fig. 3 b 9 be evenly distributed on conduit can curved segment or ablating electrode one circumferentially, this is as just example, what fill orifice 9 also can be evenly distributed on conduit can curved segment or ablating electrode circumferentially multiple, thus obtain circumferentially with longitudinally evenly perfusion stream, and be conducive to, when the different piece of conduit reclines target site tissue, all can obtaining effective cool brine flow.The quantity of fill orifice 9 is more than 2, preferred 2-9, and when fill orifice 9 be 2-3, and needs avoid being arranged on ablating electrode or the conduit place that reclines relative to target site tissue, obstruction cool brine outflow when organizing with target site of avoiding reclining.
Fig. 4 a is the localized axial profile of the cold brine infusion type radiofrequency ablation catheter illustrated according to further embodiment of this invention, wherein, the axially different position of ablating electrode arranges two groups of fill orifices 9, and Fig. 4 b and Fig. 4 c illustrates the radial section figure on sagittal plane, place, each group of fill orifice center respectively.In addition to size, the embodiment part that this embodiment is structurally different from Fig. 3 a and Fig. 3 b representative is, fill orifice 9 is divided into two groups, circumferentially, the shunting perfusion channel B/C be connected with each group of fill orifice 9 is also correspondingly divided into two groups in two the axially different positions being evenly distributed on the ablating electrode of conduit respectively.As depicted in figure 4 a-4 c, ablating electrode is provided with the two-way cool brine transfer passage A corresponding with the main paragraph part of two-way cool brine transfer passage.At the distal tip place of this two-way cool brine transfer passage A, in ablating electrode, on two different axial locations, offer 6 shuntings perfusion channel B and 6 shunting perfusion channel C along direction perpendicular to axial direction respectively, form 12 fill orifices 9.Each cool brine transfer passage A shunts perfusion channel B(or C with 3 respectively) corresponding.Cool brine transfer passage on ablating electrode and shunting perfusion channel all can adopt direct mechanical processing or cut punching on ablating electrode to obtain.Can being connected and sealed and keeping inner chamber unobstructed by the cool brine transfer passage A on curved segment part and ablating electrode of cool brine transfer passage.Cool brine transfer passage A diameter on ablating electrode is chosen as suitable in the scope of 0.3-1.5mm, be preferably 0.5mm, the diameter of 6 shuntings perfusion channel B and 6 shunting perfusion channel C and fill orifice 9 is then chosen as suitable in the scope of 0.05-0.6mm, is preferably 0.1mm.The length of each shunting perfusion channel is suitable, to ensure that its pressure differential is suitable, thus obtains uniform perfusion.Different arrangement modes can be taked between 6 shuntings perfusion channel B and 6 shunting perfusion channel C.Fig. 5 a and 5b illustrates two kinds of exemplary arrangement modes of two groups of fill orifices on ablating electrode respectively.From axially it seems, one group 6 shunting perfusion channel B and another group 6 shunting perfusion channel C can arrange (as shown in Figure 5 b) with being in alignment with each other; Also can arrange interlaced with each otherly, namely deflect various angle relative to each other, such as intersect vertically and (partially turn 90 degrees relative to each other, as shown in Figure 5 a), preferably, the angle of this deflection gets the group number of 180 degree/shunting perfusion channel, so that each component infusate flow passage can water outlet equably on the circumferential surface of ablating electrode.Above-mentioned two groups 12 shunting perfusion channel B and C can the water outlet equably on circumferential and axial on the surface of ablating electrode, more effectively take away the heat on ablating electrode surface equably, reduce the risk of ablating electrode surface incrustation, thus effectively increase depth of ablation.
The present embodiment is by opening on ablating electrode by two groups of fill orifices, and cool brine acts on surface and the inside of ablating electrode, can obtain the more effective cooling effect to ablating electrode; And realize the design of 12 fill orifices by two carrying paths, can simplifying catheter can the structure of curved segment, conveniently to manufacture; 12 fill orifices can improve the uniformity of perfusion and the risk of the whole blocking of minimizing further simultaneously, improve the safety of operation.The number of openings in the present embodiment on ablating electrode, can also for being greater than the porous of other quantity in 12 holes except 6 holes and 12 holes, and porous also can form the spread geometry being greater than 2 groups in the vertical.
Fig. 6 a and 6b illustrates respectively when the mode of blood vessel wall of reclining with conduit upper wall is applied according to the schematic diagram of cold brine infusion type radiofrequency ablation catheter of the present invention and the view in transverse section that intercepts along line II-II.Fig. 7 a and 7b illustrates respectively when the mode of blood vessel wall of reclining with conduit lower wall is applied according to the schematic diagram of cold brine infusion type radiofrequency ablation catheter of the present invention and the view in transverse section that intercepts along line III-III.Wherein, ablation catheter enters into renal artery blood vessel along central aorta at the flex under action of joystick and ablating electrode is abutted in blood vessel wall.That can see cool brine transfer passage from Fig. 6 b and 7b can curved segment part 7 and control can the bending bracing wire 10 of curved segment 6, and inside has the parts such as the wire of display or not.Tilt the center of open fill orifice 9 and the remote edge 0-5mm apart of ablating electrode, is preferably 0.8mm.Because fill orifice tilts open, cool brine flows to as shown by arrows in FIG., flows to ablating electrode side by smooth-going.See Fig. 6 b and Fig. 7 b, can curved segment part being set to about bracing wire 10 symmetry and the both sides of separation longitudinal section, bracing wire 10 place of two-way cool brine transfer passage 7, two fill orifices 9 are correspondingly also positioned at the both sides of described longitudinal section, and the line of such two fill orifices 9 is just vertical with stayguy direction.Therefore in Fig. 6 a and 7a, a fill orifice 9 is only demonstrated.Can curved segment bending and then control the recline position of conduit relative to blood vessel wall in view of utilizing joystick to control the tractive of bracing wire, because stayguy direction is vertical with the line of fill orifice, therefore fill orifice is not easily blocked by blood vessel wall because of the change of the position that reclines.
When carrying out radio-frequency ablation procedure, cold brine infusion type radiofrequency ablation catheter of the present invention can realize fast flush cooling to whole ablating electrode, and this cold brine infusion type radiofrequency ablation catheter has two or more cool brine carrying path, even if there is the cool brine transfer passage on a certain road to block, also quick cold brine perfusion can be realized by other cool brine transfer passages, reduce the temperature of ablating electrode timely and effectively, reduce ablating electrode or target site tissue local overheated, the risk of incrustation, guarantee that realizing the degree of depth melts, improve safety and the effectiveness of operation.
Exemplarily, the ablating electrode in the present invention can be made up of platinumiridio, gold, rustless steel or nickel alloy.
The present invention is not limited to the particular content described in detailed description of the invention.Cold brine infusion type radiofrequency ablation catheter provided by the present invention is not only applicable to melt sympathetic nerve treatment hypertension purposes in renal artery, is suitable for the diseases such as treatment arrhythmia yet, is also applicable to other ablative surgeries.
The explanation of above embodiment just understands core concept of the present invention for helping.It should be pointed out that for the ordinary skill in the art, under the premise without departing from the principles of the invention, some improvement and modification can also be carried out to the present invention, but these improve and modification also falls in the scope of the claims in the present invention request protection.
Claims (9)
1. a cold brine infusion type radiofrequency ablation catheter, it comprises:
Conduit pipe shaft, described conduit pipe shaft comprises for entering main paragraph in patient body and can curved segment;
Joystick, described joystick is for realize can curved segment bending;
Ablating electrode, described ablating electrode is arranged on can on curved segment far-end;
Saline transfer passage, described saline transfer passage is for carrying cool brine; With
Fill orifice, described fill orifice is for being connected to corresponding saline transfer passage and by cold brine perfusion to ablating electrode and target site;
It is characterized in that, described saline transfer passage is two or more, and each saline transfer passage is corresponding with plural described fill orifice, and the number of described fill orifice is more than 2, and described saline transfer passage be embedded in described main paragraph and described can in curved segment.
2. cold brine infusion type radiofrequency ablation catheter as claimed in claim 1, wherein, fill orifice be arranged on can in curved segment with the proximal edge of ablating electrode at a distance of 0-5mm place.
3. cold brine infusion type radiofrequency ablation catheter as claimed in claim 1, wherein, fill orifice be arranged on can in curved segment with the proximal edge of ablating electrode at a distance of 0-3mm place.
4. cold brine infusion type radiofrequency ablation catheter as claimed in claim 1, wherein, fill orifice is arranged on ablating electrode.
5. cold brine infusion type radiofrequency ablation catheter as claimed in claim 1, wherein, the perforate direction of fill orifice becomes to be less than or equal to the angle of 90 degree with the direction of principal axis distad of ablating electrode.
6. cold brine infusion type radiofrequency ablation catheter as claimed in claim 1, wherein, the perforate direction of fill orifice with the direction of principal axis distad of curved segment conduit can become the angle of 10-60 degree.
7. cold brine infusion type radiofrequency ablation catheter as claimed in claim 1, wherein, fill orifice at conduit can being circumferentially uniformly distributed of curved segment or ablating electrode.
8. cold brine infusion type radiofrequency ablation catheter as claimed in claim 1, wherein, fill orifice is connected with described saline transfer passage via shunting perfusion channel, and the diameter of described fill orifice and shunting perfusion channel is 0.05-0.6mm, and the diameter of described saline transfer passage is 0.3-1.5mm.
9. cold brine infusion type radiofrequency ablation catheter as claimed in claim 1, wherein, described saline transfer passage adopts multistage to be formed by connecting, and can curved segment part can the chamber of multi-lumen tube of curved segment the forming by forming of described saline transfer passage.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310093644.5A CN103371865B (en) | 2012-04-13 | 2013-03-21 | Cold brine perfusion type radiofrequency ablation catheter |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210108727.2 | 2012-04-13 | ||
| CN2012101087272 | 2012-04-13 | ||
| CN2012101087272A CN102631240A (en) | 2012-04-13 | 2012-04-13 | Cold brine infusion type radiofrequency ablation catheter |
| CN201310093644.5A CN103371865B (en) | 2012-04-13 | 2013-03-21 | Cold brine perfusion type radiofrequency ablation catheter |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103371865A CN103371865A (en) | 2013-10-30 |
| CN103371865B true CN103371865B (en) | 2015-04-01 |
Family
ID=46615933
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012101087272A Pending CN102631240A (en) | 2012-04-13 | 2012-04-13 | Cold brine infusion type radiofrequency ablation catheter |
| CN201310093644.5A Active CN103371865B (en) | 2012-04-13 | 2013-03-21 | Cold brine perfusion type radiofrequency ablation catheter |
| CN 201320131533 Expired - Lifetime CN203122582U (en) | 2012-04-13 | 2013-03-21 | Cold saline pouring type radio frequency ablation catheter |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2012101087272A Pending CN102631240A (en) | 2012-04-13 | 2012-04-13 | Cold brine infusion type radiofrequency ablation catheter |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201320131533 Expired - Lifetime CN203122582U (en) | 2012-04-13 | 2013-03-21 | Cold saline pouring type radio frequency ablation catheter |
Country Status (1)
| Country | Link |
|---|---|
| CN (3) | CN102631240A (en) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8774913B2 (en) | 2002-04-08 | 2014-07-08 | Medtronic Ardian Luxembourg S.A.R.L. | Methods and apparatus for intravasculary-induced neuromodulation |
| US7653438B2 (en) | 2002-04-08 | 2010-01-26 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
| US9084610B2 (en) | 2010-10-21 | 2015-07-21 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses, systems, and methods for renal neuromodulation |
| US9820811B2 (en) | 2011-08-26 | 2017-11-21 | Symap Medical (Suzhou), Ltd | System and method for mapping the functional nerves innervating the wall of arteries, 3-D mapping and catheters for same |
| US9014821B2 (en) | 2011-08-26 | 2015-04-21 | Symap Holding Limited | System and method for locating and identifying the functional nerves innervating the wall of arteries and catheters for same |
| US8702619B2 (en) | 2011-08-26 | 2014-04-22 | Symap Holding Limited | Mapping sympathetic nerve distribution for renal ablation and catheters for same |
| CN102631240A (en) * | 2012-04-13 | 2012-08-15 | 上海微创电生理医疗科技有限公司 | Cold brine infusion type radiofrequency ablation catheter |
| CN103284693B (en) * | 2012-08-24 | 2014-12-24 | 苏州信迈医疗器械有限公司 | Instrument for locating and identifying nerves in vessel wall, and application method thereof |
| CN103027750B (en) * | 2012-11-23 | 2015-02-11 | 刘宗军 | Electrical ablation balloon radiofrequency catheter in percutaneous renal artery |
| CN103893902B (en) * | 2012-12-27 | 2016-12-28 | 四川锦江电子科技有限公司 | Fluid exchange conduit |
| CN104248469B (en) * | 2013-06-28 | 2017-05-10 | 上海微创电生理医疗科技有限公司 | Cold saline perfusion ablation catheter system |
| US10039899B2 (en) | 2013-09-27 | 2018-08-07 | Covidien Lp | Multiple lumen catheters |
| KR101522662B1 (en) * | 2013-11-27 | 2015-05-27 | 주식회사 스타메드 | An electrode device for a high frequency treatment |
| CN105310766B (en) * | 2014-07-17 | 2018-11-30 | 四川锦江电子科技有限公司 | Ablation catheter end electrodes with perfusion liquid functional |
| US10034707B2 (en) | 2014-12-30 | 2018-07-31 | Biosense Webster (Israel) Ltd. | Catheter with irrigated tip electrode with porous substrate and high density surface micro-electrodes |
| CN104825226A (en) * | 2015-05-04 | 2015-08-12 | 中国人民解放军总医院 | Large ablation head and ablation device |
| CN106913373A (en) * | 2015-12-28 | 2017-07-04 | 中国科学院沈阳自动化研究所 | A kind of special-shaped balloon instrument repaired for endometrium |
| US11911093B2 (en) | 2016-09-12 | 2024-02-27 | Biosense Webster (Israel) Ltd. | Irrigation system for a catheter |
| CN109464186B (en) | 2017-09-08 | 2023-12-22 | 泽丹医疗股份有限公司 | Device and method for treating lung tumors |
| CN107961071A (en) * | 2018-01-04 | 2018-04-27 | 科塞尔医疗科技（苏州）有限公司 | A kind of radio frequency ablation catheter |
| US11478298B2 (en) | 2018-01-24 | 2022-10-25 | Medtronic Ardian Luxembourg S.A.R.L. | Controlled irrigation for neuromodulation systems and associated methods |
| JP7265014B2 (en) * | 2018-09-14 | 2023-04-25 | 杭州▲くん▼博生物科技有限公司 | High frequency ablation catheter, pulmonary high frequency ablation system, corresponding control method, control device and computer readable storage medium |
| SG11202103476SA (en) | 2018-10-06 | 2021-05-28 | Symap Medical Suzhou Limited | System and method for mapping functional nerves innervating wall of arteries, 3-d mapping and catheters for same |
| CN110575249B (en) * | 2019-09-30 | 2021-03-02 | 科塞尔医疗科技（苏州）有限公司 | Electrophysiology catheter and preparation method thereof |
| CN115813529A (en) * | 2022-10-17 | 2023-03-21 | 湖南埃普特医疗器械有限公司 | Pulse ablation device with saline water perfusion function |
| CN115813526B (en) * | 2023-02-17 | 2023-06-30 | 上海安钛克医疗科技有限公司 | Electrophysiology catheter and high-voltage pulse ablation system |
| CN116687553B (en) * | 2023-06-12 | 2023-10-10 | 成都德倍佳医疗科技有限责任公司 | Fluid controllable hemostatic front-end assembly, electrode and system thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005048858A1 (en) * | 2003-10-29 | 2005-06-02 | Universitair Medisch Centrum Utrecht | Catheter and method, in particular for ablation and like technique |
| CN201356648Y (en) * | 2009-03-04 | 2009-12-09 | 微创医疗器械(上海)有限公司 | Saline perfusion RF ablation catheter |
| CN102028538A (en) * | 2011-01-24 | 2011-04-27 | 苗毅 | Multifunctional cold circulation concentrated beam radiofrequency treatment probe |
| WO2011060200A1 (en) * | 2009-11-11 | 2011-05-19 | Innovative Pulmonary Solutions, Inc. | Systems, apparatuses, and methods for treating tissue and controlling stenosis |
| CN102119009A (en) * | 2008-07-15 | 2011-07-06 | 凯斯费特股份有限公司 | Catheter and method for improved ablation |
| CN102525647A (en) * | 2010-12-24 | 2012-07-04 | 日本来富恩株式会社 | Electrode catheter |
| CN203122582U (en) * | 2012-04-13 | 2013-08-14 | 上海微创电生理医疗科技有限公司 | Cold saline pouring type radio frequency ablation catheter |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8414570B2 (en) * | 2009-11-17 | 2013-04-09 | Bsd Medical Corporation | Microwave coagulation applicator and system |
-
2012
- 2012-04-13 CN CN2012101087272A patent/CN102631240A/en active Pending
-
2013
- 2013-03-21 CN CN201310093644.5A patent/CN103371865B/en active Active
- 2013-03-21 CN CN 201320131533 patent/CN203122582U/en not_active Expired - Lifetime
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005048858A1 (en) * | 2003-10-29 | 2005-06-02 | Universitair Medisch Centrum Utrecht | Catheter and method, in particular for ablation and like technique |
| CN102119009A (en) * | 2008-07-15 | 2011-07-06 | 凯斯费特股份有限公司 | Catheter and method for improved ablation |
| CN201356648Y (en) * | 2009-03-04 | 2009-12-09 | 微创医疗器械(上海)有限公司 | Saline perfusion RF ablation catheter |
| WO2011060200A1 (en) * | 2009-11-11 | 2011-05-19 | Innovative Pulmonary Solutions, Inc. | Systems, apparatuses, and methods for treating tissue and controlling stenosis |
| CN102525647A (en) * | 2010-12-24 | 2012-07-04 | 日本来富恩株式会社 | Electrode catheter |
| CN102028538A (en) * | 2011-01-24 | 2011-04-27 | 苗毅 | Multifunctional cold circulation concentrated beam radiofrequency treatment probe |
| CN203122582U (en) * | 2012-04-13 | 2013-08-14 | 上海微创电生理医疗科技有限公司 | Cold saline pouring type radio frequency ablation catheter |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103371865A (en) | 2013-10-30 |
| CN102631240A (en) | 2012-08-15 |
| CN203122582U (en) | 2013-08-14 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103371865B (en) | Cold brine perfusion type radiofrequency ablation catheter | |
| AU673015B2 (en) | Catheter for RF ablation with cooled electrode and method | |
| CN104220018B (en) | A kind of ablating electrode and the pouring type electrode catheter using the electrode | |
| US6611699B2 (en) | Catheter with an irrigated composite tip electrode | |
| US8128620B2 (en) | Irrigated ablation electrode having proximal direction flow | |
| CN103142304B (en) | The synchronous pulmonary artery radio frequency ablation catheter of multipole | |
| CN203280485U (en) | Multi-electrode ablation catheter | |
| CN203539434U (en) | Multi-electrode ablation catheter | |
| CN104257426B (en) | A kind of arteria renalis with sealing valve removes sympathetic nerve cool brine radio frequency ablation catheter | |
| KR20100094449A (en) | Cooled ablation catheter devices and methods of use | |
| CN102266245B (en) | Perfusion-type radiofrequency ablation catheter | |
| CN104095679A (en) | Multiple-electrode ablation catheter | |
| CN203341811U (en) | Cold saline perfusion ablation catheter system | |
| CN104248469B (en) | Cold saline perfusion ablation catheter system | |
| CN107456269B (en) | A kind of cryoablation conduit | |
| US7425216B2 (en) | System and method for treating cardiac arrest and myocardial infarction | |
| CN204147112U (en) | A kind of renal artery with seal valve removes sympathetic nerve cool brine radio frequency ablation catheter | |
| CN112353487A (en) | Medical combined ablation needle capable of monitoring pressure and ablation method | |
| CN209059423U (en) | A kind of water-cooled microwave ablation needle and its fluid injection and wicking structure, metal outer bush | |
| CN207870951U (en) | A kind of cryoablation conduit | |
| CN213940934U (en) | Medical combined ablation needle for pressure monitoring | |
| CN111281527A (en) | Cryoablation catheter | |
| CN113693714B (en) | Water-cooling internal circulation type bipolar ablation needle for electroporation and focus ablation device | |
| CN206403855U (en) | The body canal of Microwave Coagulation water cooling temperature control one for varicose treatment | |
| CN213821695U (en) | Radio frequency ablation catheter with cooling function and intravascular interventional therapy system |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 201318 Shanghai city Pudong New Area zhouputown Tianxiong road 588 Lane twenty-eighth Building No. 1-28 Patentee after: SHANGHAI MICROPORT EP MEDTECH Co.,Ltd. Address before: 201318 Shanghai city Pudong New Area zhouputown Tianxiong road 588 Lane twenty-eighth Building No. 1-28 Patentee before: SHANGHAI MICROPORT EP MEDTECH Co.,Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20220929 Address after: Room 301, 3rd Floor, Building 28, No. 1_28, Lane 588, Tianxiong Road, Pudong New Area, Shanghai, 201318 Patentee after: Shanghai Hongdian Medical Technology Co.,Ltd. Address before: Building 28, No. 1-28, Lane 588, Tianxiong Road, Zhoupu Town, Pudong New Area, Shanghai, 201318 Patentee before: SHANGHAI MICROPORT EP MEDTECH Co.,Ltd. |