CN103364574A - Automatic leukorrhea analyzer - Google Patents
Automatic leukorrhea analyzer Download PDFInfo
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- CN103364574A CN103364574A CN201310339360XA CN201310339360A CN103364574A CN 103364574 A CN103364574 A CN 103364574A CN 201310339360X A CN201310339360X A CN 201310339360XA CN 201310339360 A CN201310339360 A CN 201310339360A CN 103364574 A CN103364574 A CN 103364574A
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Abstract
The invention relates to an automatic leukorrhea analyzer, and belongs to the medical detection technology field. The automatic leukorrhea analyzer comprises a computer control system, a sampling and flushing system, a sample temperature-control device used for preserving leukorrhea samples, an automatic microscopy sampler used for drawing sample liquid from the sample temperature-control device, and an autofocus microscope used for detecting the leukorrhea sample liquid. The automatic leukorrhea analyzer also comprises a box used for containing the above systems and the above devices. The computer control system is individually and electrically connected through transmission lines to the sample temperature-control device, the automatic microscopy sampler, the autofocus microscope and the sampling and flushing system. The sample temperature-control device, the automatic microscopy sampler, the autofocus microscope and the sampling and flushing system are controlled and adjusted by the computer control system, and therefore the leukorrhea analyzer can be automatically operated in the best working state; leukorrhea sample sampling, detecting and analyzing can be completed, and dirt attached on a sampling pipeline can be cleaned timely and effectively to maintain the sampling pipeline. The automatic leukorrhea analyzer can be operated conveniently and has good popularization and application value.
Description
Technical field
The present invention relates to medical checkout equipment field, specifically is a kind of full-automatic leukorrhea analyser.
Background technology
The leukorrhea check is the big event of clinical gynaecological examination, and present leukorrhea analyser generally adopts the mode of manual smear to be put into microscopically, directly observes.Adopt this mode to exist some defectives: the virus that lies dormant in the sample and germ, to reviewer's the larger threat of health existence; In addition, pure manual operations, detection efficiency is low, and accuracy is little, is difficult to adapt to extensive, large batch of efficient detection; In addition, residual sample liquid in some its sampling lines of leukorrhea analyser tends to occur the sample cross-infection, and if maintain bad, corrosion or local biological self reproducing will occur in its pipeline, and the problems referred to above produce harmful effect to operational efficiency and the detection degree of accuracy of leukorrhea analyser.
Summary of the invention
Purpose of the present invention is to provide a kind of full-automatic leukorrhea analyser, can automatically detect a plurality of samples, and it is accurate to detect data; After the detection, this leukorrhea analyser not only in good time effective cleaning be attached to foul on the sampling line, can also carry out the pipeline maintenance, use easy to operate.
The present invention solves the technical scheme that its technical matters takes:
Full-automatic leukorrhea analyser, it is characterized in that: it comprises: computer control system, the sampling rinse-system, and the sample attemperating unit that is used for preserving the leukorrhea sample, be used for from the sample attemperating unit, drawing the automatic mirror inspection sampler of sample liquid, be used for detecting leukorrhea sample liquid automatically to focusing microscope, also comprise a casing that holds above system and device, described automatic mirror inspection sampler is arranged on the left forward side in the casing, describedly automatically focusing microscope is arranged on right forward side in the casing, described sample attemperating unit is arranged on the bottom of casing rear side, described sampling rinse-system, automatic mirror inspection sampler and automatic to having the pipeline that is connected between the focusing microscope; Described computer control system is examined sampler, automatically the focusing microscope electricity is linked to each other with sample attemperating unit, automatic mirror respectively by transmission line.
Further, described sample attemperating unit comprises sample disk, and described sample disk is provided with the through hole of accommodating test tube, and sample disk is socketed in the heat-generating disc, and sample disk can rotate with respect to heat-generating disc under the effect of rotating driving device; Described heat-generating disc bottom connects a chassis, is provided with the heat-generating pipe that is connected with power supply between spontaneous heating dish and the chassis; On heat-generating disc, also be provided with the temperature sensor that is electrically connected with controller.
Described sample disk is divided into disk body and base ring, and upper disk body is fixed with one by a plurality of uniform pillars and base ring, is provided with the through hole of accommodating test tube at upper disk body and base ring, and described through hole is uniform along the marginal portion annular of sample disk, up and down concentric; Described sample disk middle part also is provided with 2-3 fixed orifice and by this fixed orifice sample disk and the rotating driving device that is arranged on the base is coupled together.
Described heat-generating disc be the middle part with the ring bodies of cavity, the accommodating rotating driving device that is fixed on the base of cavity part, the ring bodies upper surface of heat-generating disc is provided with the heat-generating disc ring groove, the base ring of sample disk is suspended in the heat-generating disc ring groove and concentric.
Described rotating driving device comprises motor, line shaft, small pulley, large belt wheel, rotation axis and terminal pad; Be fixed on the line shaft of the motor connecting band small pulley on the base; Rotation axis upper end is provided with large belt wheel, small pulley be connected by belt between the belt wheel greatly, on rotation axis, also be provided with terminal pad, described terminal pad couples together by fixed pin and sample disk.
Between heat-generating pipe and base, also be provided with a mat insulation.
Also be provided with back-up block between heat-generating disc and the base.
Its structure of described automatic mirror inspection sampler comprises horizontal stand and the vertical support frame that can move along horizontal stand; The slide block that is provided with horizontal guide rail, lateral driver device on the described horizontal stand and can laterally moves on horizontal guide rail, a side of described slide block have two threaded holes and are connected on the vertical support frame by coupling bolt; Lateral driver device makes vertical support frame and slide block along the horizontal guide rail translation; The application of sample needle stand that is provided with longitudinal rail, longitudinal driving device on the vertical support frame and can slides along vertical support frame on longitudinal rail be provided with sample needle on the described application of sample needle stand, sample needle can be under the longitudinal driving device effect guide rail upper and lower translation longitudinally.
Described lateral driver device comprises: horizontal motor, the first belt wheel, the second belt wheel and connect the first belt wheel and the second belt wheel between the first Timing Belt; Described the first belt wheel and the second belt wheel are installed in respectively the two ends of horizontal stand lower surface, and described horizontal motor is arranged on an end of horizontal stand upper surface, and described its output shaft of horizontal motor passes horizontal stand and is connected with the first belt wheel; Web joint on the first briquetting and the vertical support frame clamps the first Timing Belt by screw or rivet, makes the interlock of vertical support frame and the first Timing Belt.
Described longitudinal driving device comprises: motor vertical, the 3rd belt wheel, four-tape wheel and the second Timing Belt, described motor vertical is installed in the upper end at its back side of vertical support frame, described the 3rd belt wheel and four-tape wheel are installed in the two ends in vertical support frame front, the output shaft of described motor vertical passes vertical support frame and connects the 3rd belt wheel, described the 3rd belt wheel is connected with described four-tape wheel by the second Timing Belt, on described the second Timing Belt the second briquetting is installed, between described slide block and the horizontal guide rail, be dovetail connecting structure between longitudinal rail and the application of sample needle stand.
Further, described automatically to focusing microscope, comprise microscope body, Nosepiece unit, eyepiece connecting cylinder group, article carrying platform, conditioner unit, move left and right unit, move forward and backward the unit, the light collecting device regulon, it is characterized in that: be provided with the move left and right unit that makes article carrying platform realize move left and right below the described article carrying platform, be provided with above the article carrying platform and move forward and backward the unit; Article carrying platform is connected on the slide block, and this slide block cooperates with microscope body, moves up and down together with article carrying platform at the effect sliding block of conditioner unit, realizes focusing; Install on the described connecting cylinder group and take the unit, this shooting unit comprises camera and transmission line, and camera is used for taking the sample image that can observe from eyepiece, and reaches computing machine in the electric signal mode through transmission line; Described Nosepiece unit, conditioner unit, move left and right unit, move forward and backward and be equipped with independently the gauge tap that is used for the control adjusting range in unit and the light collecting device regulon.
Further, described sampling rinse-system comprises waste liquid pool, the first membrane pump, service sink, sample needle, counting chamber, diluter and the second membrane pump that the liquid road links to each other; Described the second membrane pump is connected with the Precerving liquid container that Precerving liquid is housed with the soda liquor container that cleaning fluid is housed respectively by flushing line; The two ends of described counting chamber are connected with the first solenoid valve and the second solenoid valve, has the 3rd solenoid valve between between described diluter and the second membrane pump, has the 4th solenoid valve between described the second membrane pump and the soda liquor container, be provided with the 5th solenoid valve between described the second membrane pump and the Precerving liquid container, on the pipeline between the 3rd solenoid valve and the second membrane pump, also be provided with branch line, this branch line and service sink intracavity inter-connection.
The invention has the beneficial effects as follows: the present invention can be by computer control system to sample attemperating unit, automatic mirror inspection sampler, automatic control adjustment to focusing microscope and sampling rinse-system, make the leukorrhea analyser can automatically operate in optimum Working, automatically finish sampling and the detection of leukorrhea sample liquid are analyzed, and it is accurate to detect data.After the detection, this leukorrhea analyser not only in good time effective cleaning be attached to foul on the sampling line, can also carry out the pipeline maintenance, use easy to operate.
Description of drawings
Fig. 1 is the composition module diagram of full-automatic leukorrhea analyser;
Fig. 2 is the spatial structure view of sample attemperating unit;
Fig. 3 is that sample attemperating unit master looks partial sectional view;
Fig. 4 is the perspective view of sample disk;
Fig. 5 is the perspective view of heat-generating disc;
Fig. 6 is automatic mirror inspection sampler perspective view;
Fig. 7 is the backsight structural representation of automatic mirror inspection sampler;
Fig. 8 is that (partial cutaway) structural representation is looked on the left side of automatic mirror inspection sampler;
Fig. 9 is the perspective view of vertical support frame;
Figure 10 is the perspective view of horizontal stand.
Figure 11 is the microscopical side structure schematic diagram of automatically focusing;
Figure 12 is the perspective view of looking up of the horizontal move left and right structure of objective table (under Figure 11 state);
Figure 13 is the left TV structure schematic diagram that the slider level moves forward and backward structure (under Figure 11 state);
Figure 14 is the part perspective view of regulator;
Figure 15 is the part perspective view of light collecting device;
Figure 16 is the structural representation of looking up of Figure 15.
Figure 17 is the structural principle schematic diagram of sampling rinse-system;
Among the figure: 10 sample attemperating units, 101 heat-generating discs, 102 sample disks, 103 controllers, 104 temperature sensors, 105 chassis, 106 mat insulations, 107 wire guides, disk body on 108,109 heat-generating pipes, 1010 pillars, 1011 base rings, 1012 through holes, 1013 fixed orifices, 1014 fixing annular grooves, 1015 heat-generating disc ring grooves, 1016 motors, 1017 line shafts, 1018 small pulleys, 1019 terminal pads, 1020 rotation axiss, 1021 large belt wheels, 1022 fixed pins, 1023 back-up blocks, 20 automatic mirrors inspection sampler, 201 horizontal stands, 202 vertical support frames, 203 horizontal guide rails, 205 cross sliding clocks, 206 threaded holes, 2061 coupling bolts, 207 longitudinal rails, 209 application of sample needle stands, 2010 sample needles, 2011 horizontal motors, 2,012 first belt wheels, 2,013 second belt wheels, 2,014 first Timing Belts, 2015 the 3rd belt wheels, 2016 four-tapes wheel, 2017 motor verticals, 2,018 second briquettings, 2,019 first briquettings, 2020 web joints, 2,022 second Timing Belts, 30 automatically to focusing microscope, 301 microscope bodies, 3011 connecting cylinder groups, 3012 main body tops, 3013 bases, 302 Nosepiece unit, 3021 turrets, 3022 object lens the first belt wheel, 3023 object lens stepper motors, 3024 fixed mounts, 3025 object lens the second belt wheel, 303 take unit, 3031 cameras, 3032 transmission lines, 304 article carrying platforms, 305 conditioner unit, 3051 focusing stepper motors, 3052 focusing knobs, 3053 focusing the first belt wheel, 3054 focusing the second belt wheel, 3055 slide blocks, 306 move left and right unit, 3061 move left and right stepper motors, 3062 nut silk seats, 3063 move left and right screw mandrels, 3064 fixed heads, 3065 web joints, 307 move forward and backward the unit, and 3071 move forward and backward stepper motor, and 3072 move forward and backward screw mandrel, 3073 nuts, 3074 slider bases, 3075 pelleting press, 3076 supports, 308 light collecting device regulons, 3081 light harvestings are regulated stepper motor, 3082 optical collectors, 3083 optical collector fixed mounts, 3084 light harvestings are regulated upright guide rail, 3085 lighting sources, 40 sampling rinse-systems, 401 waste liquid pools, 402 first membrane pumps, 403 service sinks, 405 counting chambers, 406 diluters, 407 second membrane pumps, 408 soda liquor containers, 409 Precerving liquid containers, 4,010 first solenoid valves, 4,011 second solenoid valves, 4012 the 3rd solenoid valves, 4013 the 4th solenoid valves, 4014 the 5th solenoid valves, 4015 branch lines, 50 computer control systems.
Embodiment
Explain below with reference to Figure of description full-automatic leukorrhea analyser of the present invention being done.
Such as Fig. 1, full-automatic leukorrhea analyser of the present invention, comprise: computer control system 50, sampling rinse-system 40 and the sample attemperating unit 10 that is used for preserving the leukorrhea sample, be used for from the sample attemperating unit, drawing the automatic mirror inspection sampler 20 of sample liquid, be used for detecting leukorrhea sample liquid automatically to focusing microscope 30, also comprise a casing that holds above system and device, described automatic mirror inspection sampler 20 is arranged on the left forward side of casing, automatically focusing microscope 30 is examined the right side that sampler 20 links to each other and is arranged on casing the place ahead with described automatic mirror, described sample attemperating unit 10 is arranged on the bottom of casing rear side, described sampling rinse-system 40, automatic mirror is examined sampler 20 and automatically focusing microscope 30 is linked to each other by pipeline and circulate in the casing; Described computer control system 50 is examined sampler 20, automatically focusing microscope 30 electricity is linked to each other with sample attemperating unit 10, automatic mirror respectively by transmission line.
Such as Fig. 2, Fig. 3, described temperature control equipment, its structure comprises heat-generating disc 101, with the sample disk 102 that heat-generating disc 101 socket-connects, sample disk 102 can rotate with respect to heat-generating disc 101.Described heat-generating disc bottom also connects a chassis 105 by back-up block 1023, and in the slit between heat-generating disc bottom and chassis 105, spontaneous heating dish 101 is provided with heat-generating pipe 109 and mat insulation 106 successively to base.
Such as Fig. 4, described sample disk 102 is the circular rotating dish, it is divided into disk body 108 and base ring 1011, upper disk body 108 is fixed with one with base ring 1011 by a plurality of uniform pillars 1010, be provided with the through hole 1012 of accommodating test tube at upper disk body 108 and base ring 1011, described through hole 1012 is uniform along the marginal portion annular of sample disk 102, up and down concentric; Described sample disk 102 middle parts also are provided with 2-3 fixed orifice 1013 so that sample disk 102 and rotating driving device are coupled together, and sample disk 102 is rotated as requested.
Such as Fig. 5, described heat-generating disc 101 is that the middle part is with the ring bodies of cavity, the accommodating rotating driving device that is fixed on the chassis 105 of cavity part, the ring bodies upper surface of heat-generating disc 101 is provided with heat-generating disc ring groove 1015, and the base ring 1011 of sample disk 102 is suspended in the heat-generating disc ring groove 1015 and concentric.
Be provided with heat-generating pipe 109 in the bottom surface of heat-generating disc 101, this heat-generating pipe 109 adopts annular heat pipe, be used for heat-generating disc 101 bottom-heateds, radiation by heat-generating disc 101 and convection current are with the heat transferred test tube, sample is realized heating, 106 pairs of mat insulations can prevent heat transferred chassis 105, and based on same purpose, back-up block 1023 also can adopt thermal insulation material.The electrode of heat-generating pipe 109 is drawn the connection power supply by the hole on the base.
Such as Fig. 3, chassis 5 be provided with line shaft 1017 pass through hole, rotation axis 1020 pass through hole and wire guide 107.Rotating driving device comprises motor 1016, line shaft 1017, rotation axis 1020, small pulley 1018, large belt wheel 1021 and terminal pad 1019.Motor 1016 is fixed on the chassis 105, and the line shaft 1017 that links to each other with motor output shaft passes heat-generating disc 101 and partly is connected small pulley 1018 in heat-generating disc 101 cavitys; Rotation axis 1020 is arranged at chassis 105 central authorities rotationally, it passes heat-generating disc 101 and partly connects large belt wheel 1021 in heat-generating disc 101 cavitys, be connected by belt between small pulley 1018 and the large belt wheel 1021, be positioned at large belt wheel 1021 upper horizontal at rotation axis 1020 and be provided with the terminal pad 1019 that is fixedly connected with rotation axis 20, described terminal pad 1019 upper surfaces are provided with 2-3 fixed pin 1022, and the fixed pin 1022 on the described terminal pad 1019 is rear by nut lock by the fixed orifice 1013 of sample disk 102.
For improving the adaptability of the fixed pin 1022 on the terminal pad 1019, satisfy and the cooperating of many specifications sample disk 102, terminal pad 1019 upper surfaces are provided with circular groove, the central authorities of circular groove are the circular pressing plate that is fixed by screws on the terminal pad 1019, consist of a ring groove by the outward flange of circular pressing plate and circular groove; Fixed pin 1022 is set to T-shaped, and its large first end places in the ring groove, and cutting can be along this ring groove turned position, and little head end is rear by nut lock by the fixed orifice 1013 of sample disk 102.
Be provided with the temperature sensor 104 that detects the heat-generating disc temperature on heat-generating disc 101 or near it, described temperature sensor 104 is connected with controller 103 by transmission line, can control the temperature that heating tube provides by controller 103 in good time.The angular signal of sample disk 102 leads to controller 103 via wire by wire guide 107, with the rotary state of control sample disk 102.
Such as Fig. 6, described automatic mirror inspection sampler 20, its structure comprise horizontal stand 201 and the vertical support frame 202 that can move along horizontal stand.
Such as Fig. 6 with such as Fig. 9, be provided with horizontal guide rail 203, lateral driver device and can be along the cross sliding clock 205 of horizontal stand 201 transverse shiftings on horizontal guide rail 203 on the described horizontal stand 201, a side of described slide block 205 has two threaded holes 206 and is connected on the vertical support frame 202 by coupling bolt 2061.Be dovetail connecting structure between cross sliding clock 205 and the horizontal guide rail 203.
Described lateral driver device comprises: horizontal motor 2011, the first belt wheel 2012, the second belt wheel 2013 and connect the first belt wheel and the second belt wheel between the first Timing Belt 2014; Described the first belt wheel 2012 and the second belt wheel 2013 are installed in respectively the two ends of horizontal stand 201 lower surfaces, described horizontal motor 2011 is arranged on an end of horizontal stand upper surface, and described horizontal motor 2011 its output shafts pass horizontal stand 201 and are connected with the first belt wheel 2012 of horizontal stand lower surface.Horizontal motor 2011 rotates and then drives the first belt wheel 2012 and rotates, and drives the second belt wheel 2013 via the first Timing Belt 2014 and rotates thereupon.
Be provided with gauge tap at horizontal stand 201, such as limit switch or optoelectronic switch, controllable levels motor 2011 rotates.Can control the displacement of the first Timing Belt 2014 by gauge tap, namely control vertical support frame 202 displacement in the horizontal direction.Such as Fig. 6 and Fig. 9, the application of sample needle stand 209 that is provided with longitudinal rail 207, longitudinal driving device and can on longitudinal rail 207, slides along vertical support frame 202 at described vertical support frame 202, be provided with sample needle 2010 on the described application of sample needle stand 209, sample needle 2010 can be under the longitudinal driving device effect longitudinally guide rail 207 move up and down.Be connected by the dovetail structure between longitudinal rail 207 and the application of sample needle stand 209.
Fig. 9, described longitudinal driving device comprises: motor vertical 2017, the 3rd belt wheel 2015, four-tape wheel the 2016 and second Timing Belt 2022, described motor vertical 2017 is installed in the upper end at vertical support frame 202 its back sides, described the 3rd belt wheel 2015 and four-tape wheel 2016 are installed in the two ends in vertical support frame 202 fronts, the output shaft of described motor vertical 2017 passes vertical support frame 202 and connects the 3rd belt wheel 2015, described the 3rd belt wheel 2015 is connected with described four-tape wheel 2016 by the second Timing Belt 2022, on described the second Timing Belt 2022 the second briquetting 2018 is installed.When motor vertical 2017 rotates, drive the 3rd belt wheel 2015,2022 interlocks of four-tape wheel the 2016 and second Timing Belt, fix and the second Timing Belt 2022 is clamped because the application of sample needle stand 209 on the second briquetting 2018 and the longitudinal rail 207 is bolted, so application of sample needle stand 209 is realized moving up and down; Because the guide effect of longitudinal rail 207 so that application of sample needle stand 209 translation in vertical plane, sample needle 2010 just can be under the longitudinal driving device effect longitudinally guide rail 207 move up and down, realize the sampling operation.
Described horizontal stand 201 is demountable structure with vertical support frame 202.
During use, computer control system 50 is by the running of horizontal motor 2011, control vertical support frame 202 moves back and forth from initial position along horizontal guide rail 203 and moves to the working position, running by motor vertical 2017, control application of sample needle stand 209 on vertical support frame 202 longitudinally guide rail 207 move up and down, when slowly vertically downward motion of sample needle 2010, arrive lower dead center, filling sample liquid; After sample needle 2010 has been annotated sample, computer control system 50 is received signal, the antiport of motor vertical 2017, sample needle 2010 is vertically upward motion slowly, arrive after top dead center, horizontal motor 2011 revolutions are when sample needle moves to initial position, sampling finishes, and can implement subsequent job.
Such as Figure 11, described automatically to focusing microscope 30, comprise microscope body 301, Nosepiece unit 302, take unit 303, article carrying platform 304, conditioner unit 305, move left and right unit 306, move forward and backward the parts such as unit 307, light collecting device regulon 308.
Described microscope body 301 comprises main body top 3012 and base 3013, and it is microscopical basis, and other each unit all is attached on the microscope body 301, and connecting cylinder group 3011 is the web member that former eyepiece is installed on the microscope body 301.
In the present invention, install on the connecting cylinder group 3011 and take unit 303, this shooting unit 303 comprises camera 3031 and transmission line 3032, camera 3031 is used for taking the sample image that can observe from eyepiece, and reach computer control system 50 automated image analysis centers in the electric signal mode through transmission line 3032, to obtain the pattern detection data.
Described Nosepiece unit 302 comprises turret 3021, object lens the first belt wheel 3022, object lens stepper motor 3023, fixed mount 3024, object lens the second belt wheel 3025 etc.Object lens stepper motor 3023 is fixed on the microscope body 301 by fixed mount 3024, object lens the first belt wheel 3022 connects the output shaft of described object lens stepper motor 3023, object lens the second belt wheel 3025 is fixedly installed on the outer ring of turret 3021, between object lens the first belt wheel 3022 and object lens the second belt wheel 3025, be connected with driving belt, when needs were adjusted object lens, 3021 rotations reached automatic adjusting object lens purpose thereby object lens stepper motor 3023 rotates the drive turret.In Nosepiece unit 302, also be provided with the gauge tap of control turret 3021 rotational angles, such as optoelectronic switch or contact switch etc.
Article carrying platform 304 is the level of state, and is provided with the move left and right unit 306 that makes article carrying platform 304 realize move left and right below it, is provided with above the article carrying platform 304 and moves forward and backward unit 307.Article carrying platform 304 is connected on the slide block 3055, and this slide block 3055 cooperates with microscope body 301, moves up and down together with article carrying platform 304 at the effect sliding block 3055 of conditioner unit 305, realizes focusing.
Such as Figure 11, Figure 12, move left and right unit 306 comprises move left and right stepper motor 3061, nut silk seat 3062, move left and right screw mandrel 3063 and fixed head 3064.Move left and right stepper motor 3061 is fixed on the fixed head 3064 by web joint 3065, and this fixed head 3064 is connected as a single entity with slide block 3055 and moves up and down synchronously.Nut silk seat 3062 is fixed on the article carrying platform 304, move left and right screw mandrel 3063 passes nut silk seat 3062 and move left and right stepper motor 3061, fixed head 3064 is embedded in the dovetail groove of article carrying platform 4 bottom surfaces, when move left and right stepper motor 3061 rotates, promote nut silk seat 3062 by move left and right screw mandrel 3063, and then promote article carrying platform 304 realization move left and right.The displacement of article carrying platform 304 is limited by independent gauge tap, such as optoelectronic switch or contact switch etc.
Such as Figure 11, Figure 13, move forward and backward unit 307 comprise move forward and backward stepper motor 3071, move forward and backward screw mandrel 3072, the part such as nut 3073, slider base 3074 and pelleting press 3075.Moving forward and backward stepper motor 3071 is fixed on the article carrying platform 304 by support 3076, slider base 3074 places above the article carrying platform 304, riser at slider base 3074 is equipped with nut 3073, move forward and backward screw mandrel 3,072 one ends and move forward and backward stepper motor 3071 by support 3076 connections, the other end passes nut 3073 and matches with it, is provided with elastic pressuring plate device 3075 at slider base 3074 and is used for pressing solidly pattern detection counting chamber (perhaps microscope specimen slide).When the mobile stepper motor 3071 in front and back rotates, move forward and backward screw mandrel 3072 and via nut 3073 slider base 3074 is moved forward and backward.The displacement of slider base 3074 is limited by independent gauge tap, such as optoelectronic switch or contact switch etc.
Such as Figure 11, Figure 15 and shown in Figure 16, light collecting device regulon 308 comprises the parts such as light harvesting adjusting stepper motor 3081, optical collector 3082, optical collector fixed mount 3083, light harvesting adjusting upright guide rail 3084 and lighting source 3085.Regulate upright guide rail 84 in the outside of slide block 3055 by light harvesting and be connected with optical collector fixed mount 3083, light harvesting is regulated the side that stepper motor 3081 is fixed on slide block 3055, the output terminal of this motor moves up and down optical collector fixed mount 3083 by the mode of gear and tooth bar, optical collector 3082 is fixed on the optical collector fixed mount 3083, thereby, when moving up and down, can automatically regulate by optical collector 3082 distance with lighting source 3085.Optical collector 3082 moves up and down distance and limited by independent gauge tap, such as optoelectronic switch or contact switch etc.
Each motor, each gauge tap and shooting unit all connect computer control system 50, according to the procedure order action that sets.During use, take unit 303 image information is uploaded to computing machine, computer control system 50 is judged image definition according to the focus value of taking the unit, then control the motor of microscope each several part, make image reach the most clear state, this helps the user to realize fast automatic analysis image, and is simple to operate, automaticity is high, has greatly improved work efficiency.
Such as Figure 17: described sampling rinse-system 40, its structure comprises: the waste liquid pool 401 that the liquid road links to each other, the first membrane pump 402, service sink 403, sample needle 2010, counting chamber 405, diluter 406 and the second membrane pump 407, described the second membrane pump 407 is connected with the Precerving liquid container 409 that Precerving liquid is housed with the soda liquor container 408 that cleaning fluid is housed respectively by flushing line, the two ends of described counting chamber are connected with the first solenoid valve 4010 and the second solenoid valve 4011, has the 3rd solenoid valve 4012 between between described diluter 406 and the second membrane pump 407, has the 4th solenoid valve 4013 between described the second membrane pump 407 and the soda liquor container 408, be provided with the 5th solenoid valve 4014 between described the second membrane pump 407 and the Precerving liquid container 409, on the pipeline between the 3rd solenoid valve 4012 and the second membrane pump 407, also be provided with branch line 4015, this branch line 4015 and service sink 403 intracavity inter-connections.
Adopt above-mentioned sampling rinse-system to carry out the method for sample sampling and flushing, may further comprise the steps:
1). the operation detection instrument, enter and detect the interface, click initialization, instrument resets;
2). the detection cup position in the sample disc runs to the position at sample needle 2010 places, and sample needle 2010 moves down to be inserted into and detects in the cup;
3). the first solenoid valve 4010 and the second solenoid valve 4011 are opened simultaneously, diluter 406(prior art) sampling is in counting chamber 403, behind the sample introduction, the first solenoid valve 4010 and the second solenoid valve 4011 are closed simultaneously, at this moment, sample arm resets, and the microscopy automatic camera is analyzed, sample needle 2010 motions are inserted in the service sink 403, and diluter 406 resets;
4). then, the first solenoid valve 4010, the second solenoid valve 4011, the 3rd solenoid valve 4012 and the 4th solenoid valve 4013 are opened simultaneously, 407 operations of the first membrane pump, the cleaning fluid that extracts in the soda liquor container 408 carries out pipeline-cleaning, drain in the service sink 403 by sample needle 2010, realize that sample needle 2010 inwalls wash; The liquid outlet of cleaning fluid on the tubular body wall of service sink 403 from branch line 4015 flows out, and sample needle 2010 outer walls are washed; Cleaning fluid drains in the waste liquid pool 401 through the second membrane pump 402;
5). the first battery valve 4010, the second solenoid valve 4011, the 3rd solenoid valve 4012 and the 4th solenoid valve 4013 are closed, and the first membrane pump 402 and the second membrane pump 407 are out of service;
6). waste liquid is opened the first battery valve 4010, the second solenoid valves 4011, the 3rd solenoid valve 4012, the 5th battery valve 4014 after discharging simultaneously, starts the second membrane pump 407, and the Precerving liquid that extracts in the Precerving liquid container 409 washes maintenance to flushing line;
7). the sample detection process is all finished.
Except the described technical characterictic of instructions, be the known technology of those skilled in the art.
Claims (9)
1. full-automatic leukorrhea analyser, it is characterized in that, comprise: computer control system, the sampling rinse-system, and the sample attemperating unit that is used for preserving the leukorrhea sample, be used for from the sample attemperating unit, drawing the automatic mirror inspection sampler of sample liquid, be used for detecting leukorrhea sample liquid automatically to focusing microscope, also comprise a casing that holds above system and device, described automatic mirror inspection sampler is arranged on the left forward side in the casing, describedly automatically focusing microscope is arranged on right forward side in the casing, described sample attemperating unit is arranged on the bottom of casing rear side, described sampling rinse-system, automatic mirror inspection sampler and automatic to having the pipeline that is connected between the focusing microscope; Described computer control system is examined sampler, automatically the focusing microscope electricity is linked to each other with sample attemperating unit, automatic mirror respectively by transmission line.
2. full-automatic leukorrhea analyser according to claim 1, it is characterized in that, described sample attemperating unit comprises sample disk, described sample disk is provided with the through hole of accommodating test tube, sample disk is socketed in the heat-generating disc, and sample disk can rotate with respect to heat-generating disc under the effect of rotating driving device; Described heat-generating disc bottom connects a chassis, is provided with the heat-generating pipe that is connected with power supply between spontaneous heating dish and the chassis; On heat-generating disc, also be provided with the temperature sensor that is electrically connected with controller.
3. full-automatic leukorrhea analyser according to claim 2 is characterized in that, its structure of described automatic mirror inspection sampler comprises horizontal stand and the vertical support frame that can move along horizontal stand; The slide block that is provided with horizontal guide rail, lateral driver device on the described horizontal stand and can laterally moves on horizontal guide rail, a side of described slide block have two threaded holes and are connected on the vertical support frame by coupling bolt; Lateral driver device makes vertical support frame and slide block along the horizontal guide rail translation; The application of sample needle stand that is provided with longitudinal rail, longitudinal driving device on the vertical support frame and can slides along vertical support frame on longitudinal rail be provided with sample needle on the described application of sample needle stand, sample needle can be under the longitudinal driving device effect guide rail upper and lower translation longitudinally.
4. full-automatic leukorrhea analyser according to claim 3 is characterized in that, described lateral driver device comprises: horizontal motor, the first belt wheel, the second belt wheel and connect the first belt wheel and the second belt wheel between the first Timing Belt; Described the first belt wheel and the second belt wheel are installed in respectively the two ends of horizontal stand lower surface, and described horizontal motor is arranged on an end of horizontal stand upper surface, and described its output shaft of horizontal motor passes horizontal stand and is connected with the first belt wheel; Web joint on the first briquetting and the vertical support frame clamps the first Timing Belt by screw or rivet, makes the interlock of vertical support frame and the first Timing Belt.
5. full-automatic leukorrhea analyser according to claim 4, it is characterized in that, described longitudinal driving device comprises: motor vertical, the 3rd belt wheel, four-tape wheel and the second Timing Belt, described motor vertical is installed in the upper end at its back side of vertical support frame, described the 3rd belt wheel and four-tape wheel are installed in the two ends in vertical support frame front, the output shaft of described motor vertical passes vertical support frame and connects the 3rd belt wheel, described the 3rd belt wheel is connected with described four-tape wheel by the second Timing Belt, on described the second Timing Belt the second briquetting is installed, between described slide block and the horizontal guide rail, be dovetail connecting structure between longitudinal rail and the application of sample needle stand.
6. full-automatic leukorrhea analyser according to claim 5 is characterized in that, the corresponding gauge tap that is provided with the horizontal motor of control and motor vertical work respectively on described horizontal stand and vertical support frame.
7. full-automatic leukorrhea analyser according to claim 6, it is characterized in that, described automatically to focusing microscope, comprise microscope body, Nosepiece unit, eyepiece connecting cylinder group, article carrying platform, conditioner unit, move left and right unit, move forward and backward the unit, the light collecting device regulon, it is characterized in that: be provided with the move left and right unit that makes article carrying platform realize move left and right below the described article carrying platform, be provided with above the article carrying platform and move forward and backward the unit; Article carrying platform is connected on the slide block, and this slide block cooperates with microscope body, moves up and down together with article carrying platform at the effect sliding block of conditioner unit, realizes focusing; Install on the described connecting cylinder group and take the unit, this shooting unit comprises camera and transmission line, and camera is used for taking the sample image that can observe from eyepiece, and reaches computing machine in the electric signal mode through transmission line; Described Nosepiece unit, conditioner unit, move left and right unit, move forward and backward and be equipped with independently the gauge tap that is used for the control adjusting range in unit and the light collecting device regulon.
8. full-automatic leukorrhea analyser according to claim 7 is characterized in that, described sampling rinse-system comprises waste liquid pool, the first membrane pump, service sink, sample needle, counting chamber, diluter and the second membrane pump that the liquid road links to each other; Described the second membrane pump is connected with the Precerving liquid container that Precerving liquid is housed with the soda liquor container that cleaning fluid is housed respectively by flushing line; The two ends of described counting chamber are connected with the first solenoid valve and the second solenoid valve, has the 3rd solenoid valve between between described diluter and the second membrane pump, has the 4th solenoid valve between described the second membrane pump and the soda liquor container, be provided with the 5th solenoid valve between described the second membrane pump and the Precerving liquid container, on the pipeline between the 3rd solenoid valve and the second membrane pump, also be provided with branch line, this branch line and service sink intracavity inter-connection.
9. full-automatic leukorrhea analyser according to claim 8, it is characterized in that, described service sink is body structure in a tubular form, its lower end contraction mouth connects the first membrane pump and waste liquid pool by pipeline, be provided with the liquid outlet of flushing sample needle outer wall at the tubular body wall of service sink, this liquid outlet is connected with branch line.
Priority Applications (1)
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| CN201310339360XA CN103364574A (en) | 2013-08-06 | 2013-08-06 | Automatic leukorrhea analyzer |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201310339360XA CN103364574A (en) | 2013-08-06 | 2013-08-06 | Automatic leukorrhea analyzer |
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| CN108896776A (en) * | 2018-06-27 | 2018-11-27 | 沈阳工业大学 | Fluid analyte meter feeding mechanism |
| CN109142356A (en) * | 2018-08-06 | 2019-01-04 | 王鲁生 | A kind of leukorrhea micro-image mycelia automatic identification equipment and method |
| CN109254007A (en) * | 2018-11-08 | 2019-01-22 | 深圳市瑞图生物技术有限公司 | Gynecological secretion detection device |
| CN114441390A (en) * | 2020-10-30 | 2022-05-06 | 深圳市瑞图生物技术有限公司 | Concurrent time sequence control method, sperm quality analyzer and storage medium |
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Application publication date: 20131023 |