CN103364255B - For the evenly mixing device of cellanalyzer - Google Patents
For the evenly mixing device of cellanalyzer Download PDFInfo
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- CN103364255B CN103364255B CN201210088033.7A CN201210088033A CN103364255B CN 103364255 B CN103364255 B CN 103364255B CN 201210088033 A CN201210088033 A CN 201210088033A CN 103364255 B CN103364255 B CN 103364255B
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Abstract
The present invention discloses that a kind of evenly mixing device for cellanalyzer comprises can the cylinder of rotating 360 degrees roller and carrying test tube rack, and wherein, described cylinder roller is fixed together, and described drums inside has and holds the space of test tube rack; Described test tube rack can hold multiple test tube.During above-mentioned evenly mixing device work, test tube rack holds multiple test tube, test tube rack is arranged in cylinder, and roller rotates and drives drum rotating 360 ° or 180 °, thus invisible spectro blood sample can be mixed.Because the evenly mixing device in the embodiment of the present invention once shakes up operation to the multiple test tubes in test tube rack, compared to oscillating uniform device of the prior art, the number of times capturing test tube not only can be reduced owing to once shaking up multiple test tube, and add the quantity once shaking up test tube, thus improve the mixing efficiency of cellanalyzer.
Description
Technical field
The present invention relates to medical sanitary apparatus, more particularly, relate to a kind of evenly mixing device for cellanalyzer.
Background technology
Cellanalyzer is one of hospital clinical inspection application instrument widely, along with the development of making rapid progress of computer technology in recent years, the technology of blood cell analysis is also hived off from three and is turned to five to hive off, from two-dimensional space and then turn to three dimensions, and we also notice that five sorting techniques of modern cellanalyzer are many and have employed the technology identical with current FA flow cytometer, as scattered light detection technique, sheath Flow Technique, laser technology etc.
In cellanalyzer, automatically need before sampling to carry out fully mixing ability sampling and detection further to blood sample.The patent No. is the device that the Chinese patent of CN01123219.6 discloses a kind for the treatment of of sample of blood products, comprises conveyer, for moving box one by one on predefined paths; Agitating device, it is with at least one picking device, this picking device can be started by drive unit, a selected test tube is at least picked from box motionless on path, at least pick a selected test tube in box motionless from path, make test tube away from box, shake test tube by tube back box, and sampler, it can extract the sample of specified rate out from the test tube shaken in advance put back in box.The test tube clamp filling blood sample is held on the grabbing device that captures on it even by sample mix by above-mentioned agitating device.During operation, at least pick two test tubes selected in the box of picking device from the path being fixed on conveyer, then test tube is shaken twice together.Above-mentioned agitating device is when shaking test tube, picking device is needed to capture test tube respectively, such as, picking device in this patent once can capture two selected test tubes, when needs carry out married operation to ten invisible spectro blood samples, picking device captures two test tubes at every turn, then carries out twice shake operation to two test tubes simultaneously, so need to carry out five grasping manipulations, five shake operations.For the blood sample analyzing batch, its mixing efficiency is on the low side.
Therefore, how to work out a kind of evenly mixing device improving mixing efficiency in cellanalyzer, become the technical matters that those skilled in the art are urgently to be resolved hurrily.
Summary of the invention
Therefore, the object of the invention is to, a kind of evenly mixing device for cellanalyzer is provided, to improve the mixing efficiency of cellanalyzer.
To achieve these goals, the invention discloses a kind of evenly mixing device for cellanalyzer, comprise can rotating 360 degrees roller and carrying test tube rack cylinder, wherein, described cylinder roller is fixed together, and described drums inside has the space holding test tube rack.
Preferably, in the evenly mixing device of cellanalyzer, described roller is provided with belt above-mentioned, is coordinated with the first motor by belt gear.
Preferably, above-mentioned in the evenly mixing device of cellanalyzer, also clamping device is comprised.
Preferably, above-mentioned in the evenly mixing device of cellanalyzer, described clamping device comprises the second motor, fixed sturcture, screw rod, voussoir and block, wherein, described second motor is fixed on described fixed sturcture, described screw rod one end is through the circular hole on described fixed sturcture and described second motors, described voussoir is set in its inside surface on screw rod and matches with the screw thread on described screw rod, described fixed sturcture bottom has the groove holding described voussoir, described block and described groove match.
Preferably, above-mentioned in the evenly mixing device of cellanalyzer, described clamping device is fixed on web joint.
Preferably, above-mentioned in the evenly mixing device of cellanalyzer, also comprise the optoelectronic switch controlling described second motor operation, described voussoir is provided with the shell fragment triggering described optoelectronic switch.
Preferably, above-mentioned in the evenly mixing device of cellanalyzer, also comprise setting on which cylinder and block the stop motion mechanism of described test tube rack.
Preferably, above-mentioned in the evenly mixing device of cellanalyzer, described stop motion mechanism comprises spring, fixed sturcture, syndeton and rolling bearing, wherein, described syndeton upper end is provided with shrinkage pool that a diameter matches with spring for holding described spring, described spring wherein one section be placed in shrinkage pool, one section is exposed outside shrinkage pool; Syndeton lower end extends to form forward an axle matched with rolling bearing, and described rolling bearing is set on this axle, and the front end of axle arranges nut and gets off from landing axle to prevent the axis of rolling; Described fixed sturcture is fixed on cylinder wall.
Preferably, above-mentioned in the evenly mixing device of cellanalyzer, described evenly mixing device is fixed by bracing frame.
Preferably, cylinder both sides are provided with microswitch.
The evenly mixing device for cellanalyzer in the embodiment of the present invention comprises can the cylinder of rotating 360 degrees roller and carrying test tube rack, and wherein, described cylinder roller is fixed together, and described drums inside has and holds the space of test tube rack; Described test tube rack can hold multiple test tube.
During above-mentioned evenly mixing device work, test tube rack holds multiple test tube, test tube rack is arranged in cylinder, and roller rotates and drives drum rotating 360 ° or 180 °, thus invisible spectro blood sample can be mixed.Because the evenly mixing device in the embodiment of the present invention once shakes up operation to the multiple test tubes in test tube rack, compared to oscillating uniform device of the prior art, the number of times capturing test tube not only can be reduced owing to once shaking up multiple test tube, and add the quantity once shaking up test tube, thus improve the mixing efficiency of cellanalyzer.
Accompanying drawing explanation
Fig. 1 is the cellanalyzer perspective view that the embodiment of the present invention provides;
Fig. 2 is the cellanalyzer plan structure schematic diagram that the embodiment of the present invention provides;
Fig. 3 is the plan structure schematic diagram of the test tube rack that the embodiment of the present invention provides;
Fig. 4 be the test tube rack that provides of the embodiment of the present invention look up structural representation;
Fig. 5 and Fig. 6 is the multi-angle structure schematic diagram that the embodiment of the present invention provides towing device;
Fig. 7 is the detonation configuration schematic diagram that the embodiment of the present invention provides towing device;
Fig. 8 is the side-looking structural representation that the embodiment of the present invention provides gearing;
Fig. 9 is the detonation configuration schematic diagram that the embodiment of the present invention provides gearing;
Figure 10 is the evenly mixing device perspective view that the embodiment of the present invention provides;
Figure 11 is the detonation configuration schematic diagram of the evenly mixing device that the embodiment of the present invention provides;
Figure 12 is the clamping device perspective view that the embodiment of the present invention provides;
Figure 13 is the clamping device detonation configuration schematic diagram that the embodiment of the present invention provides
Figure 14 is the stop motion mechanism detonation configuration schematic diagram that the embodiment of the present invention provides;
Figure 15 is the stop motion mechanism sectional structure schematic diagram that the embodiment of the present invention provides;
Figure 16 is the stop motion mechanism mounting structure schematic diagram that the embodiment of the present invention provides.
Embodiment
Describe the present invention below in conjunction with accompanying drawing, the description of this part is only exemplary and explanatory, should not have any restriction to protection scope of the present invention.
As depicted in figs. 1 and 2, this sample introduction sampler comprises loading attachment, and the luggage of going forward side by side of the test tube rack for depositing the test tube filling sample blood carries; Towing device 4, delivers to evenly mixing device for the test tube deposited by sample introduction sampler; Evenly mixing device 5, for mixing invisible spectro sample blood; Puncture sampling apparatus 6, for analyzing blood cell composition; Discharge mechanism 7, for unloading the test tube rack completing sample introduction sampling.
Above-mentioned sample introduction sampler specific works process is: the test tube rack 3 in loading attachment, deliver under the effect of towing device 4 in evenly mixing device 5, after evenly mixing device 5 mixes, by towing device 4, the test tube support of carried sample blood is delivered to puncture sampling apparatus 6 again, sample; In sample analysis process, the test tube carried again enters in evenly mixing device 5 and repeatedly repeatedly mixes, and makes mixing more abundant; Ultimate analysis detection terminates rear test tube rack 3 and is pushed out and is discharged in the carrying disk 8 of discharge mechanism 7.
As shown in Figure 3 and Figure 4, the test tube rack 3 in the present embodiment can hold multiple test tube 26, and blood sample is contained in test tube 26, and by plug closes, and the spacing of adjacent test tube 26 is identical.
Test tube rack 3 in the present embodiment comprises base plate 30, sidewall 31 and annular sleeve 32, and sidewall 31 is vertically set on base plate 30, forms the main support structure of whole test tube rack 3; Annular sleeve 32 is arranged on sidewall 31, and annular sleeve 32 or annular sleeve 32 form with sidewall 31 space holding test tube 26, and in the present embodiment, preferred lateral arrangement has ten annular sleeve 32, for holding ten test tubes 26; In order to prevent test tube 26 from shaking, in this test tube rack 3, the longitudinal direction of each annular sleeve 32 all has additional an annular sleeve 32, has predeterminable range between the annular sleeve 32 longitudinally arranged, and the test tube 26 making to be positioned at annular sleeve 32 is stressed more reasonable.
Wherein, in above-mentioned test tube rack 3, annular sleeve 32 can be fixed on sidewall 31 by physical construction, such as, adopt screw to be fixed on sidewall 31; Can also integral structure be set to, form integral structure in particular by injection moulding.
Conveniently install, sidewall 31 top is provided with the groove 34 identical with test tube 26 spacing, and horizontal direction is provided with step 32.The base plate 30 of test tube rack 3 is provided with cavernous structure, to facilitate the clamping of follow up device, this cavernous structure is square opening structure particularly, and this square opening comprises sleeve pipe and this sleeve pipe is fixed on the stiffening rib on base plate 30, stiffening rib disperses layout to surrounding centered by sleeve pipe, not only ensure that the intensity of sleeve pipe, also save raw material to greatest extent.Above-mentioned base plate 30 can be set to integral structure, in particular by the integral formula structure of injection molding with cavernous structure.
Loading attachment in the embodiment of the present invention comprises carrying disk 1 and pushes away sample block 2, and wherein, carrying disk 1 can hold test tube rack 3, and test tube rack 3 is slidably disposed on carrying disk 1; Push away one end that sample block 2 is arranged on carrying disk 1, and test tube rack 3 can be promoted move to the direction away from carrying disk 1 other end.
Particularly, the both sides of carrying disk 1 are provided with guide pole, push away sample block 2 and also can carry out longitudinal sliding motion along guide pole through this guide pole.When the every side of above-mentioned carrying disk 1 is provided with a guide pole, carrying disk 1 is provided with clamping part near the edge of carrying disk 1 loading surface and away from the edge of carrying disk 1 loading surface, and this pushes away the acting in conjunction lower slider of sample block at clamping part and guide pole; When the every side of above-mentioned carrying disk 1 is provided with at least two guide poles, every root guide pole be arranged in parallel, and now this pushes away sample block 2 and can promote test tube rack 3 smoothly under the effect of guide pole and move to predetermined direction.
Test tube rack 3 vertically moving on carrying disk 1 completes under the impetus pushing away sample block 2, and when test tube rack 3 moves to end from the top of carrying disk 1, test tube rack 3 enters cross track and complete transverse shifting under the effect of towing device 4.
The structure of discharge mechanism is identical with loading attachment, and the two difference is a loading place being positioned at whole sample introduction sampler, unloading place being positioned at described sample introduction sampler.
Towing device 4 as shown in Figures 5 to 9, this towing device 4 can be the rack and pinion drive mechanism that motor 36 drives, also can be the cam mechanism that motor 36 drives, under the driving of motor 36, by under rack and pinion drive mechanism or cam mechanism transmission, all can realize the upper and lower rectilinear motion in the portion that pulls of towing device 4, this portion of pulling is specially handgrip.Handgrip moves upward, arrive top limit position time, handgrip gos deep in the cavernous structure bottom test tube rack 3, whole towing device 44 transversely guide rail transverse shifting thus drive test tube rack 3 at predetermined moving on rails; When handgrip moves downward, handgrip is separated with test tube rack 3, and what whole towing device 4 just can be independent moves in predetermined track.
Only describe for rack pinion at this, this towing device 4 comprises the handgrip 39 and driving mechanism that can move up and down, and driving mechanism drives handgrip 39 to move up and down.This driving mechanism comprises the holder 42 that can be sleeved on cross track particularly, this holder 42 is provided with motor 36 by fixed cap 44, the output shaft of motor 36 is fixed with gear 37; Be fixed on the orienting lug 41 on holder 42; Slidably be arranged on the slide block on orienting lug 41, the tooth bar 38 this slide block being provided with handgrip 39 and matching with gear 37, wherein, handgrip 39 is provided with cylindrical hole 54, is fixed on slide block by the pin be arranged on cylindrical hole 54 by handgrip; With slide block is added the clamping plate 48 being held in orienting lug 41.
When towing device 4 arrives precalculated position, rotated by motor 36 driven gear 37, the rotation of gear 37 makes tooth bar 38 move upward along tooth bar 38 orienting lug 41.In tooth bar 38 motion process, tooth bar 38 abuts against on the madial wall 31 of orienting lug 41 without the side of profile of tooth, moves up and down along orienting lug 41.On the side of orienting lug 41, the cylinder 52 of a projection is had at tooth bar 38, in the process that moves up and down, cylinder 52 is positioned at the strip groove 53 in the middle of orienting lug 41, play the effect of mechanical position limitation, this cylinder 52 can be solid cylindrical pin, also can be a pulley that can freely rotate.
When gear 37 arrives certain altitude, in the cavernous structure that the tooth bar 38 be fixed on slide block drives handgrip 39 to insert on test tube rack 3 base plate 30, like this, test tube rack 3 towing device 4 can drive test tube rack 3 to move in transverse movement simultaneously.When this device is without the need to driving test tube rack 3 to move, motor 36 rotates backward certain angle, and tooth bar 38 moves downward backhaul, and handgrip 39 departs from the cavernous structure bottom test tube rack 3.
This holder 42 is provided with the through hole 43 matched with cross slide way, wherein, reduce the wearing and tearing of holder 42, the two ends of through hole 43 are respectively arranged with orienting sleeve 50, and this orienting sleeve 50 is fixed by mounting flange 49.
In order to better hold the working time of handgrip 39, this towing device 4 is also provided with photoelectric sensor 45, wherein, slide block is fixed with the sheet metal 51 for starting photoelectric sensor 45, when handgrip 39 moves to predeterminated position, sheet metal 51 contacts with photoelectric sensor 45, and start photoelectric sensor 45 and run, now photoelectric sensor 45 transmits control signal CD-ROM drive motor 36 antikinesis.
The opposite side of tooth bar 38 is provided with a sheet metal 51, and in tooth bar 38 motion process, sheet metal 51 also moves up and down thereupon, and during arrival precalculated position, sheet metal 51 triggers the photoelectric sensor 45 being positioned at front end, thus controls the duty of motor 36.
Whole test tube rack 3 towing device 44 is driven by main frame motor 36, Timing Belt (not outpouring) is fastened on clamping plate 48, through hole 43 and cross slide way (not outpouring) clearance fit, make test tube rack 3 towing device 4 under the drive of motor 36 transversely guide rail do transverse movement.
Tooth bar 38 secures a roller 40, and roller 40 is between test tube rack 3 cross slide way, and in test tube rack 3 towing device 4 transverse movement, roller rolls along test tube rack 3 cross slide way inside surface, thus plays guide effect.Whole like this test tube rack 3 towing device 4 is led by cross slide way and roller 40 in motion process, avoids whole test tube rack 3 towing device 4 to be vacillate now to the left, now to the right in motion.
After test tube rack 3 is transported to evenly mixing device 5 by towing device 4, evenly mixing device 5 shakes test tube rack 3, thus the test tube 26 that shake test tube rack 3 is placed.
As shown in Figure 10 and Figure 11, this evenly mixing device 5 comprises can the roller 9 of rotating 360 degrees, the cylinder 11 of roller 10 and carrying test tube rack 3, and wherein, cylinder 11 is fixed together with roller 9 and roller 10, and cylinder 11 inside has the space holding test tube rack 3; Roller 9 and roller 10 rotate under the driving effect of motor 13.It is inner that test tube rack 3 is transported to cylinder 11 under the effect of towing device 4, and it is inner to be fixed on cylinder 11, and evenly mixing device is fixed on above described cross slide way by bracing frame.
The course of work of middle evenly mixing device 5 will be described in detail below.
Preferred in the present embodiment, motor 13 is rotated by V belt translation driving rolls 9 and roller 10, thus realizes whole row's test tube 26 same time and rotate 180 ° or 360 °, thus sample is fully mixed.After mixing terminates, optoelectronic switch 19 sends signal to motor 13, and motor 13 stops operating.
In order to optimize above-mentioned evenly mixing device 5, as shown in Figure 12 to Figure 13, evenly mixing device 5 in the present embodiment is also provided with clamping device 14, the clamping device 14 just braked after the test tube rack 3 in evenly mixing device 5 rotates 180 ° or 360 °, this clamping device 14 carries out mechanical braking to whole cylinder 11.
Optoelectronic switch 19 and clamping device 14 is provided with in cylinder 11 upper end.This clamping device 14 comprises motor 16, fixed sturcture 17, screw rod 18, voussoir 21 and block 22, wherein, motor 13 is fixed on fixed sturcture 17, screw rod 18 one end is connected with motor 13 through the circular hole on fixed sturcture 17, voussoir 21 is set in its inside surface on screw rod 18 and matches with the screw thread on screw rod 18, motor 13 drives screw rod 18 to rotate thus drives voussoir 21 to move downward, fixed sturcture 17 bottom has the groove 34 holding voussoir 21, when voussoir 21 does not move downward, just inside the groove 34 being contained in this fixed sturcture 17, block 22 matches with the groove 34 of voussoir 21.Whole clamping device 14 is fixed on one piece of web joint 171 being fixed on the bracing frame of evenly mixing device by fixed sturcture 17 lower end peripheral and is fixed, and this web joint 171 is hollow, and middle hole can hold the motion of voussoir about 21.Block 22 is fixed on the cylinder 11 of evenly mixing device 5, and by braking block 22, thus index drum 11 rotates.
After mixing completes, shell fragment 20 triggers optoelectronic switch 19, and motor 16 quits work, motor 16 drives voussoir 21 downward by screw rod 18 simultaneously, block 22 inserts in voussoir 21, plays mechanical braking, with prevent due to rotator inertia and photoelectric sensor is delayed or lost efficacy cause break through phenomenon.
In order to optimize above-mentioned evenly mixing device 5 further, as shown in Figure 14 to Figure 16, evenly mixing device 5 in the present embodiment is also provided with stop motion mechanism 15, as shown in the figure, this stop motion mechanism 15 comprises spring 27, fixed sturcture 25, syndeton 24 and rolling bearing 23, wherein, syndeton 24 upper end is provided with shrinkage pool that a diameter matches with spring 27 for holding spring 27, spring 27 wherein one section be placed in shrinkage pool, one section is exposed outside shrinkage pool; Syndeton 24 is fixed in the mounting hole 28 of fixed sturcture 25, and the upper surface of the spring 27 on it withstands on the lower surface of the upper end of fixed sturcture 25 and produces certain elasticity tension by the top pressure in this face; Fixed sturcture 25 is fixed on cylinder 11 sidewall 31; Syndeton 24 lower end extends to form forward an axle matched with rolling bearing 23, and described rolling bearing 23 is set on this axle, and the front end of axle arranges nut and gets off from landing axle to prevent the axis of rolling.
Cylinder 11 is fixed between two rollers 9 and roller 10, the positioning guiding structure 29 matched with test tube rack 3 sidewall 31 step 32 being provided with a bar shaped in cylinder 11, and the base plate 30 of test tube rack 33, sidewall 31 and step 32 lean and move in cylinder 11.After test tube rack 33 and the test tube 26 that carries enter cylinder 11, by stop motion mechanism 15, test tube rack 3 is positioned in cylinder 11, in case test tube rack 3 is subjected to displacement in cylinder 11 in blending process.Motor 16 is with movable belt pulley 12 and roller 9 and roller 10 to rotate, thus makes the test tube 26 of whole ranking on test tube rack 33 carry out 360 ° of rotations.
Below will describe stop motion mechanism 15 course of work in detail.
Rolling bearing 23 is stuck in the groove 34 of test tube rack 3, and when towing device 4 promotes test tube rack 3, rolling bearing 23 is crossed test tube rack 3 groove 34 and lifts, and the spring 27 now in stop motion mechanism 15 compresses, and test tube rack 3 passes through smoothly.After reaching correct position, the horizontal not strength of towing device 4 pairs of test tube racks 3, at this moment rolling bearing 23 is stuck in the groove 34 on test tube rack 3 just, the horizontal free movement of test tube rack 3 is obstructed, and test tube rack 3 closely leans bottom cylinder 11 under the downward effect of spring 27, in cylinder 11 rotary course, test tube rack 3 can not offset in cylinder 11.
In addition, be provided with microswitch in the both sides of cylinder 11, inner to guarantee that whole test tube rack 3 and all test tubes 26 are all positioned at cylinder 11.The rolling bearing 23 of stop motion mechanism 15 is stuck in the groove 34 of test tube rack 3, promote test tube rack 3, rolling bearing 23 is crossed test tube rack 3 groove 34 and lifts, spring 27 now in stop motion mechanism 15 compresses, test tube rack 3 passes through smoothly, after reaching correct position, test tube rack 3 does not laterally stress, rolling bearing 23 is stuck in groove 34 just, the horizontal free movement of test tube rack 3 is obstructed, and test tube rack 3 closely leans bottom cylinder 11 under the effect of spring 27, in cylinder 11 rotary course, test tube rack 3 can not offset in cylinder 11.
Claims (8)
1. the evenly mixing device for cellanalyzer, it is characterized in that, comprise can rotating 360 degrees roller and carrying test tube rack cylinder, wherein, described cylinder roller is fixed together, and described drums inside has the space holding test tube rack, and described test tube rack comprises base plate, sidewall and annular sleeve, described sidewalls orthogonal is arranged on described base plate, forms the supporting construction of whole test tube rack; Described annular sleeve is arranged on described sidewall, and described annular sleeve and described sidewall form the space holding test tube; Also comprise setting on which cylinder and block the stop motion mechanism of described test tube rack, described stop motion mechanism comprises spring, fixed sturcture, syndeton and rolling bearing, wherein, described syndeton upper end is provided with shrinkage pool that a diameter matches with spring for holding described spring, described spring wherein one section be placed in shrinkage pool, one section is exposed outside shrinkage pool; Syndeton lower end extends to form forward an axle matched with rolling bearing, and described rolling bearing is set on this axle, and the front end of axle arranges nut and gets off from landing axle to prevent the axis of rolling; Described fixed sturcture is fixed on cylinder wall.
2., as claimed in claim 1 for the evenly mixing device of cellanalyzer, it is characterized in that, described roller is provided with belt, coordinated with the first motor by belt gear.
3., as claimed in claim 2 for the evenly mixing device of cellanalyzer, it is characterized in that, also comprise clamping device.
4. as claimed in claim 3 for the evenly mixing device of cellanalyzer, it is characterized in that, described clamping device comprises the second motor, fixed sturcture, screw rod, voussoir and block, wherein, described second motor is fixed on described fixed sturcture, described screw rod one end is through the circular hole on described fixed sturcture and described second motors, described voussoir is set in its inside surface on screw rod and matches with the screw thread on described screw rod, described fixed sturcture bottom has the groove holding described voussoir, the groove match on described block and described voussoir.
5., as claimed in claim 4 for the evenly mixing device of cellanalyzer, it is characterized in that, described clamping device is fixed on web joint.
6., as claimed in claim 5 for the evenly mixing device of cellanalyzer, it is characterized in that, also comprise the optoelectronic switch controlling described second motor operation, described voussoir is provided with the shell fragment triggering described optoelectronic switch.
7., as claimed in claim 1 for the evenly mixing device of cellanalyzer, it is characterized in that, described evenly mixing device is fixed by bracing frame.
8., as claimed in claim 1 for the evenly mixing device of cellanalyzer, it is characterized in that, described cylinder both sides are provided with microswitch.
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