CN1033565A - A kind of processing technique of refined powder of marvellous taro - Google Patents

Abstract

(or put into jar after collecting and add 3～5 times of 45～60% ethanol by 40～100 order coarse powder after smashing to pieces through pulverizing for Rhizoma amorphophalli tuber (angle, sheet), the powerful stirring 0.5～2 hour, centrifugal and 90 orders sieve, solid content adds 3～5 times of weight 45～50% ethanol, repeat (or the powerful stirring of 45～50% ethanol liquid of being back to back of extracting secondary, till the effluent clarification), the gained solid content adds 1～2 times of weight dehydrated alcohol (95%), stir half an hour, centrifugal collection concentrate is in 60 ℃～80 ℃ oven dry down, aseptic, packing.This pharmacy and capsule have cholesterol reducing, blood fat and hypoglycemic activity.

Description

A kind of processing technique of refined powder of marvellous taro

The invention belongs to the biochemical process technology of medicinal konjaku powder.

Rhizoma amorphophalli tuber (dry weight) contains glucomannan about 40%.Increase (Japanese Rhizoma amorphophalli research association report 1979 such as former three grand grades, 27) sugar tolerance of having reported konjak glucomannan improves effect, the result shows that oral konjak glucomannan liquid when taking glucose can suppress the rising of blood glucose and insulin, rattan chapter (Japanese Patent Publication 57-146713) far away is found heavy polysaccharide (comprising glucomannan), oligosaccharide and derivant thereof have the obvious functions of blood sugar effect, move (Japanese threpsology's magazines 26 such as Qi Jie, 113.1968) reported that the glucomannan in the Rhizoma amorphophalli has the effect that suppresses mouse serum and the rising of total cholesterol of liver value, and inhibiting size is relevant with the molecular weight and the purity of glucomannan.Be the big more effect of molecular weight good more (Kiriyama, 1972, a), the high more effect of purity good more (Kiriyama, 1972, b).The water solublity (dash and increase wise .1983) that must keep glucomannan in addition.In order to obtain highly purified medicinal konjaku powder, the bright tuber of employing Rhizoma amorphophallis such as Sngiyama grinds the centrifugal insoluble matter of removing in the presence of 10～100 times of water, solution is dialysed to flowing water and removed inorganic salt, obtains konjak glucomannan (USP3-20 ℃ of following lyophilizing, 856,945).But this method equipment complexity, the cost height is not suitable for industrial-scale production.

The objective of the invention is to use simple equipment, cheap cost is with the highly purified medicinal konjaku powder of industrial-scale production.

Main contents of the present invention:

1. brute force stirs with impurity such as extracting inorganic salt, alkaloid and partially proteins in 45～60% alcoholic solution of 40～100 purpose konjac meals 3～5 times of weight after pulverizing (or smashing to pieces),

2. remove alcoholic solution, starch and Rhizoma amorphophalli fine powder of low quality with centrifugal filtration or vacuum filtration;

3. the dehydrated alcohol (95%) that the solid content that sieves is added 1～2 times of weight stirs extracting and dehydration down, dries then, packs.

Concrete technological process is as follows:

Rhizoma amorphophalli (angle) sheet collects 40～100 order coarse powder → put into jar and adds 3～5 times of 45～60% ethanol → brute force and stir 0.5～2 hour → centrifugal and 90 orders and sieve through pulverizing or smashing to pieces → sieve → and solid content adds the above-mentioned extracting secondary of 3～5 times of weight 45～50% ethanol → repeat (or 45～50% alcoholic solution of being back to back are powerful stir till the effluent clarification) → solid content and adds 1～2 times of weight dehydrated alcohol (95%) → stirring half an hour → centrifugal collection essence powder → 60 ℃～80 ℃ oven dry, aseptic, packing.

Advantage of the present invention and effect:

1. the medicinal konjaku powder with this law processing has kept the water solublity of glucomannan and the natural character of formation gel.Recovery rate is 78～82% of a coarse powder, and glucomannan content reaches about 85% of dry weight, and free from extraneous odour, can be for directly oral.Through animal and clinical observation, nontoxic pair of effect;

2. this law is simple than aqueous solution dialysis-lyophilization equipment, without lyophilizing and cryogenic equipment, and small investment, cost is low, is convenient to commercial production;

3. Rhizoma amorphophalli tablet and the capsule made from the medicinal smart powder of this law processing proves that through Huaxi Medical Univ's clinical observation there was a significant difference to all decline to some extent of non-insulin-dependent diabetes mellitus people blood glucose, glycolated hemoglobin.Cholesterol and triglyceride to the diabetes hyperlipemia patient all have obvious decline, and high density lipoprotein then rises to some extent, and blood fat only fluctuates in normal range and the normal patient of blood fat takes medicine afterwards.In addition, animal experiment shows with the medicinal konjaku powder of this law processing has significant reduction effect to the symptom of mice serum hypercholesterolemia.

Embodiment one:

Slice food made from Amorphophallus rivieri is crushed into former powder with the plant pulverizer, and sieving and getting 40～100 order components is coarse powder.Take by weighing the 300g coarse powder and stirred 0.5～2 hour in 50% ethanol of five times of weight, 100 order nylon cloths filter, and the powder after the filtration drops in 50% ethanol of 4 times of weight again and stirs extracting, repeats above-mentioned extracting secondary.Solid content after extracting is with 1 times of weight absolute ethyl alcohol and stirring half an hour, in 70 ℃ of baking ovens, dry after removing by filter ethanol, medicinal konjaku powder 236 grams, yield is 78.6%.

Its chemical constituent is analyzed as follows:

Moisture content: 9.88%

(the following over dry re-computation % that presses)

Total saccharic: 99.05

Glucomannan: 89.17

Nitrogen: 0.13

Ash: 1.35

Total alkaloids: 0.05

Embodiment two:

The taro angle is coarse powder through electronic smashing to pieces, sieve and collect 40～80 order coarse powder 274kg, put into 45% alcoholic solution that jar adds four times of coarse powder weight, the powerful stirring 30 minutes, liquid phase is removed in centrifugal filtration, solid content drops into 45% ethanol that adds treble amount solid content in the retort and stirs, and the repeated centrifugation extracting is once used and the absolute ethyl alcohol and stirring of solid content equivalent 30 minutes at last, centrifugal filtration, Gu it is dry that shape is put under 60 ℃～80 ℃ mobile hot blasts, gets the 255kg coarse powder, yield is 80%.

Its chemical constituent detects as follows:

Moisture content: 15%

(the following over dry re-computation % that presses)

Total saccharic: 96.65

Glucomannan: 84.81

Nitrogen: 0.14

Ash: 1.5

Total alkaloids: 0.135

Claims (3)

1, a kind of technology of processed konjaku powder, its flow process is: Rhizoma amorphophalli angle (dry tablet) pulverized (or smashing to pieces) and sieved → coarse powder → solvent extraction → filtration → drying → packing.It is characterized in that extracting and dehydrant are ethanol.

2, according to the described processing technique of refined powder of marvellous taro of claim 1, it is characterized in that: at extracting inorganic salt, alkaloid and protein phase, concentration of alcohol is 40～60%, and in the water smoking, concentration of alcohol is anhydrous (more than 95%).

3, processing technique of refined powder of marvellous taro according to claim 1 and 2 is characterized in that: at extracting inorganic salt, alkaloid and protein phase, the weight ratio of ethanol and coarse powder is: ethanol: coarse powder equals 3～5: 1; In the water smoking, ethanol: solid content (smart powder) equals 1～2: 1.