CN103340967A - Traditional Chinese medicine composition for treating aphtha and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating aphtha and preparation method thereof Download PDFInfo
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- CN103340967A CN103340967A CN2013102909599A CN201310290959A CN103340967A CN 103340967 A CN103340967 A CN 103340967A CN 2013102909599 A CN2013102909599 A CN 2013102909599A CN 201310290959 A CN201310290959 A CN 201310290959A CN 103340967 A CN103340967 A CN 103340967A
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- 239000003814 drug Substances 0.000 title claims abstract description 31
- 208000002399 aphthous stomatitis Diseases 0.000 title claims abstract description 21
- 239000000203 mixture Substances 0.000 title claims abstract description 21
- 238000002360 preparation method Methods 0.000 title claims abstract description 12
- 239000000843 powder Substances 0.000 claims abstract description 25
- 239000002994 raw material Substances 0.000 claims abstract description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 20
- 241001057584 Myrrha Species 0.000 claims description 15
- 239000000725 suspension Substances 0.000 claims description 9
- 239000002674 ointment Substances 0.000 claims description 7
- 238000000034 method Methods 0.000 claims description 6
- 239000004570 mortar (masonry) Substances 0.000 claims description 6
- 230000001954 sterilising effect Effects 0.000 claims description 6
- 238000004659 sterilization and disinfection Methods 0.000 claims description 6
- 238000003756 stirring Methods 0.000 claims description 6
- 210000000582 semen Anatomy 0.000 claims description 5
- 238000001035 drying Methods 0.000 claims description 4
- 239000011449 brick Substances 0.000 claims description 3
- 230000007159 enucleation Effects 0.000 claims description 3
- 239000012535 impurity Substances 0.000 claims description 3
- 235000011837 pasties Nutrition 0.000 claims description 3
- 238000000247 postprecipitation Methods 0.000 claims description 3
- 239000002244 precipitate Substances 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 8
- 208000002193 Pain Diseases 0.000 abstract description 3
- 229910052956 cinnabar Inorganic materials 0.000 abstract 2
- 240000007311 Commiphora myrrha Species 0.000 abstract 1
- 235000006965 Commiphora myrrha Nutrition 0.000 abstract 1
- 244000168525 Croton tiglium Species 0.000 abstract 1
- 244000301850 Cupressus sempervirens Species 0.000 abstract 1
- 235000007265 Myrrhis odorata Nutrition 0.000 abstract 1
- 240000008866 Ziziphus nummularia Species 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 231100000331 toxic Toxicity 0.000 abstract 1
- 230000002588 toxic effect Effects 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 description 4
- 239000000853 adhesive Substances 0.000 description 4
- 230000001070 adhesive effect Effects 0.000 description 4
- 239000011505 plaster Substances 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 231100000397 ulcer Toxicity 0.000 description 4
- 206010007134 Candida infections Diseases 0.000 description 3
- 208000007027 Oral Candidiasis Diseases 0.000 description 3
- 241000287411 Turdidae Species 0.000 description 3
- 201000003984 candidiasis Diseases 0.000 description 3
- 235000013339 cereals Nutrition 0.000 description 3
- 210000004195 gingiva Anatomy 0.000 description 3
- 210000002200 mouth mucosa Anatomy 0.000 description 3
- 231100000614 poison Toxicity 0.000 description 3
- 230000001737 promoting effect Effects 0.000 description 3
- 230000000306 recurrent effect Effects 0.000 description 3
- 239000003440 toxic substance Substances 0.000 description 3
- 206010020565 Hyperaemia Diseases 0.000 description 2
- 206010040943 Skin Ulcer Diseases 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 238000002651 drug therapy Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 210000000214 mouth Anatomy 0.000 description 2
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- 231100000019 skin ulcer Toxicity 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 206010004542 Bezoar Diseases 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- 241000222122 Candida albicans Species 0.000 description 1
- 206010010774 Constipation Diseases 0.000 description 1
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 description 1
- 241000201295 Euphrasia Species 0.000 description 1
- 208000032139 Halitosis Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- XQFRJNBWHJMXHO-RRKCRQDMSA-N IDUR Chemical compound C1[C@H](O)[C@@H](CO)O[C@H]1N1C(=O)NC(=O)C(I)=C1 XQFRJNBWHJMXHO-RRKCRQDMSA-N 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010028034 Mouth ulceration Diseases 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 201000007100 Pharyngitis Diseases 0.000 description 1
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 description 1
- 206010039424 Salivary hypersecretion Diseases 0.000 description 1
- 208000008630 Sialorrhea Diseases 0.000 description 1
- 229930003471 Vitamin B2 Natural products 0.000 description 1
- 238000013019 agitation Methods 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 229940095731 candida albicans Drugs 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 208000002173 dizziness Diseases 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003172 expectorant agent Substances 0.000 description 1
- 230000003419 expectorant effect Effects 0.000 description 1
- 150000002333 glycines Chemical class 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 210000005036 nerve Anatomy 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 210000003254 palate Anatomy 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 230000000144 pharmacologic effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 238000010926 purge Methods 0.000 description 1
- 229960002477 riboflavin Drugs 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 238000010025 steaming Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000002636 symptomatic treatment Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
The invention discloses a traditional Chinese medicine composition for treating aphtha and a preparation method thereof. The key point of the technical scheme is as follows: the traditional Chinese medicine composition for treating aphtha is a medicament prepared from the following raw materials in parts by weight: 2-6 parts of jujube, 0.1-0.3 part of croton, 1-3 parts of sublimated cinnabar powder, 0.1-0.3 part of golden cypress, 0.1-0.3 part of myrrh and 0.1-0.3 part of cinnabar. The invention further discloses a preparation method of the traditional Chinese medicine composition for treating aphtha. The traditional Chinese medicine composition for treating aphtha disclosed by the invention has the functions of clearing away heat and toxic materials, astringing dampness and sore and eliminating dampness and relieving pain, and is remarkable in curative effect, quick in effect and free from side effect and economic and practical. Clinical test results show that according to the medicine for treating aphtha, the patient in less extent is cured in 1-3 days while the patient in great extent is cured in 4-7 days, so that the cure rate reaches 98%.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition that can effectively treat aphtha, the invention still further relates to the preparation method of Chinese medicine composition.
Background technology
Aphtha is the superficial ulcer that occurs on the oral mucosa, big I from the grain of rice to the Semen Glycines size, circular or avette, ulcer surface is recessed, hyperemia on every side.Ulcer has characteristics such as periodicity, recurrent and self limiting, good sending out in lip, cheek, lingual margin etc.Simultaneously with complication, can concurrent halitosis, General Symptomies such as red swelling of gingiva, chronic pharyngitis, constipation, headache, dizziness, nauseating, weak, irritated, heating, lymphadenectasis.At present, the method for the treatment of aphtha is a lot, but all is symptomatic treatment basically, and these Therapeutic Method are purpose to ease the pain or to reduce recurrent number mainly, and price is low and the special good medicine of therapeutic effect is also few.
Summary of the invention
Main purpose of the present invention is to remedy the deficiency on the existing treatment aphtha method, and provides a kind of effect to treat the Chinese medicine composition of aphtha preferably.
Another object of the present invention provides the preparation method of the Chinese medicine composition of this treatment aphtha, and this preparation technology is simple, is easy to control.
Technical scheme of the present invention is achieved in that a kind of Chinese medicine composition for the treatment of aphtha, and it is the medicament that is formed by following parts by weight of Chinese traditional medicine preparation of raw material: Fructus Choerospondiatis 2-6 part, Fructus Crotonis 0.1-0.3 part, Vermilion powder 1-3 part, Cortex Phellodendri 0.1-0.3 part, Myrrha 0.1-0.3 part and Cinnabaris 01-0.3 part.
The medicament of the Chinese medicine composition for the treatment of aphtha of the present invention is unguentum.
A kind of preparation method for the treatment of the Chinese medicine composition of aphtha is characterized in that may further comprise the steps: (1) is boiled enucleation with Fructus Choerospondiatis and is placed the sterilization mortar to be ground into the mud shape; (2) get clean Semen Crotonis, pulverize, with multilamellar oil-Absorbing Sheets parcel, heat little a heatable brick bed, squeezing is deoiled, and takes out every 2 days and grinds and change paper again 1 time, and as above method squeezing six, seven times to oil is degree to the greatest extent, takes out, and is fine ground, crosses 400 mesh sieves; (3) Cortex Phellodendri, Myrrha are milled into 400 order fine powders; (4) get clean Cinnabaris after Cinnabaris water flies.It is as follows that Cinnabaris water flies over journey: Cinnabaris is pulverized place in the mortar container, add clear water and grind to form pasty state, add water again and stir, coarse powder namely sinks, and pours out top suspension immediately, and the coarse grain of sinking grinds again, add water and stir, pour out top suspension, so repeatable operation, till the Cinnabaris porphyrize, Impurity removal that at last can not suspendible merges the suspension of pouring out, leave standstill, treat that post precipitation pours out the clear water of top, will grind to form smalls after the drying precipitate, it is standby to cross 400 mesh sieves; (5) with the powder that obtains in step (1), step (2), step (3) and the step (4) and Vermilion powder according to described ratio mix homogeneously after, be prepared into unguentum through sterilization treatment.
Using method: picking 3.4-10.2 restrains ointment, places on about 1.5 square centimeters adhesive plaster, is affixed on fontanel cave or Shenting point place, and according to patient's the state of an illness and the age, the stickup time is not wait to 6 hours in 30 minutes.
Each medicine pharmacological action among the present invention:
Fructus Choerospondiatis: promoting flow of QI and blood, nourish heart, calm the nerves.
Fructus Crotonis: rush down cold amassing, orifice opening, by expectorant, row water, parasite killing.
The Vermilion powder: counteracting toxic substances, parasite killing, dampness is eliminated the phlegm.
Cortex Phellodendri: heat clearing and damp drying, pathogenic fire purging are arranged except steaming, detoxify effects such as treating skin ulcer.
Myrrha: effects such as promoting blood circulation and stopping pain, detumescence and promoting granulation are arranged.
Cinnabaris (water flies the back): tranquilizing mind; Heat-clearing and toxic substances removing; Make eye bright.
The invention has the beneficial effects as follows in the selection of pharmaceutical formulation collocation the symptom characteristic according to aphtha, mix have heat-clearing and toxic substances removing, removing dampness is held back skin ulcer, the Chinese medicine formula of the effect of dampness analgesic therapy, evident in efficacy, instant effect, have no side effect and economical and practical, clinical test results shows, with this Drug therapy aphtha, recovery from illness in the lighter 1-2 days, recovery from illness in weight person 4-5 days, cure rate is up to 98%.
The specific embodiment
Take by weighing raw material by following proportioning:
1, Fructus Choerospondiatis 2 grams, Fructus Crotonis 0.1 gram, Vermilion powder 1 gram, Cortex Phellodendri 0.1 gram, Myrrha 0.1 gram, Cinnabaris 0.1 gram;
2, Fructus Choerospondiatis 4 grams, Fructus Crotonis 0.2 gram, Vermilion powder 2 grams, Cortex Phellodendri 0.2 gram, Myrrha 0.2 gram, Cinnabaris 0.2 gram;
3, Fructus Choerospondiatis 6 grams, Fructus Crotonis 0.3 gram, Vermilion powder 3 grams, Cortex Phellodendri 0.3 gram, Myrrha 0.3 gram, Cinnabaris 0.3 gram;
4, Fructus Choerospondiatis 2 grams, Fructus Crotonis 0.2 gram, Vermilion powder 2 grams, Cortex Phellodendri 0.2 gram, Myrrha 0.2 gram, Cinnabaris 0.2 gram;
5, Fructus Choerospondiatis 2 grams, Fructus Crotonis 0.3 gram, Vermilion powder 3 grams, Cortex Phellodendri 0.3 gram, Myrrha 0.3 gram, Cinnabaris 0.3 gram;
6, Fructus Choerospondiatis 4 grams, Fructus Crotonis 0.1 gram, Vermilion powder 1 gram, Cortex Phellodendri 0.1 gram, Myrrha 0.1 gram, Cinnabaris 0.1 gram;
7, Fructus Choerospondiatis 4 grams, Fructus Crotonis 0.3 gram, Vermilion powder 3 grams, Cortex Phellodendri 0.3 gram, Myrrha 0.3 gram, Cinnabaris 0.3 gram;
8, Fructus Choerospondiatis 6 grams, Fructus Crotonis 0.1 gram, Vermilion powder 1 gram, Cortex Phellodendri 0.1 gram, Myrrha 0.1 gram, Cinnabaris 0.1 gram;
9, Fructus Choerospondiatis 6 grams, Fructus Crotonis 0.2 gram, Vermilion powder 2 grams, Cortex Phellodendri 0.2 gram, Myrrha 0.2 gram, Cinnabaris 0.2 gram.
Preparation method: (1) is boiled enucleation with Fructus Choerospondiatis and is placed the sterilization mortar to be ground into the mud shape; (2) get clean Semen Crotonis, pulverize, with multilamellar oil-Absorbing Sheets parcel, heat little a heatable brick bed, squeezing is deoiled, and takes out every 2 days and grinds and change paper again 1 time, and as above method squeezing six, seven times to oil is degree to the greatest extent, takes out, and is fine ground, crosses 400 mesh sieves; (3) Cortex Phellodendri, Myrrha are milled into 400 order fine powders; (4) get clean Cinnabaris after Cinnabaris water flies.It is as follows that Cinnabaris water flies over journey: Cinnabaris is pulverized place in the mortar container, adds an amount of clear water and grind to form pasty state, add the water stirring again, coarse powder namely sinks, and pours out top suspension immediately, and the coarse grain of sinking grinds again, add water and stir, pour out top suspension, so repeatable operation, till the Cinnabaris porphyrize, Impurity removal that at last can not suspendible merges the suspension of pouring out, leave standstill, treat that post precipitation pours out the clear water of top, will grind to form smalls after the drying precipitate, it is standby to cross 400 mesh sieves; (5) with the powder that obtains in step (1), step (2), step (3) and the step (4) and Vermilion powder according to described ratio mix homogeneously after, be prepared into unguentum through sterilization treatment.
Case 1:
Cui so-and-so, man, 62 years old; live area just outside a city gate, Changyuan County town, patient's mouth festers, repeatedly outbreak; once took medicines such as detoxicating tablet of cow-bezoar and vitamin B2 and do not feel any better in two months, in June, 2012 my clinic diagnosis, found on inspection that there was the ulcer of Semen phaseoli radiati size at the lip of the tongue and lower-left gingiva place; be recurrent oral ulceration after diagnosing; the about 7 gram ointment of picking place on about 1.5 square centimeters adhesive plaster, are attached to the fontanel cave and take off after 6 hours; ulcerate disease shape in oral cavity disappears after 5 days, and recurrence is not seen in further consultation after 6 months.
Case 2:
Flourish so-and-so, woman, 2 years old half, live normal villages and small towns, Changyuan County, in May, 2013, patient generated heat 39 °, agitation, sialorrhea can not be eaten, and oral mucosa is generally red and swollen, tongue limit, gingiva and palate have many circular blisters, after diagnosing Wei Bi Eng toxicity herpes, with about this medicine 3.4 grams, place on about 1.5 square centimeters adhesive plaster, be attached to Shenting point and take off after last 40 minute, recovery from illness after 2 days.
Case 3:
Cui so-and-so, woman, 25 years old, the thrush a few days is suffered from by Wei Zhuan town, Changyuan County, does not feel any better through multiple Drug therapy, my clinic diagnosis and treatment of in November, 2011 are thrush after diagnosing, and thrush is that Candida albicans is invaded oral mucosa, form the disease of leukasmus film at mucomembranous surface, this leukasmus film need exert oneself just can wipe, and wipes the back mucous hyperemia, with placing on about 1.5 square centimeters adhesive plaster about these medicine 10 grams, be attached to the fontanel cave and removed about last 1 hour, recovery from illness in 5 days.
Claims (3)
1. a Chinese medicine composition for the treatment of aphtha is characterized in that it being the medicament that is formed by following parts by weight of Chinese traditional medicine preparation of raw material: Fructus Choerospondiatis 2-6 part, Fructus Crotonis 0.1-0.3 part, Vermilion powder 1-3 part, Cortex Phellodendri 0.1-0.3 part, Myrrha 0.1-0.3 part and Cinnabaris 01-0.3 part.
2. the Chinese medicine composition for the treatment of aphtha according to claim 1, it is characterized in that: described medicament is unguentum.
3. preparation method for the treatment of the Chinese medicine composition of aphtha is characterized in that may further comprise the steps: (1) is boiled enucleation with Fructus Choerospondiatis and is placed the sterilization mortar to be ground into the mud shape; (2) get clean Semen Crotonis, pulverize, with multilamellar oil-Absorbing Sheets parcel, heat little a heatable brick bed, squeezing is deoiled, and takes out every 2 days and grinds and change paper again 1 time, and as above method squeezing six, seven times to oil is degree to the greatest extent, takes out, and is fine ground, crosses 400 mesh sieves; (3) Cortex Phellodendri, Myrrha are milled into 400 order fine powders; (4) get clean Cinnabaris after Cinnabaris water flies.It is as follows that Cinnabaris water flies over journey: Cinnabaris is pulverized place in the mortar container, add clear water and grind to form pasty state, add water again and stir, coarse powder namely sinks, and pours out top suspension immediately, and the coarse grain of sinking grinds again, add water and stir, pour out top suspension, so repeatable operation, till the Cinnabaris porphyrize, Impurity removal that at last can not suspendible merges the suspension of pouring out, leave standstill, treat that post precipitation pours out the clear water of top, will grind to form smalls after the drying precipitate, it is standby to cross 400 mesh sieves; (5) with the powder that obtains in step (1), step (2), step (3) and the step (4) and Vermilion powder according to described ratio mix homogeneously after, be prepared into unguentum through sterilization treatment.
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| CN201310290959.9A CN103340967B (en) | 2013-07-11 | 2013-07-11 | Traditional Chinese medicine composition for treating aphtha and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107233448A (en) * | 2017-07-07 | 2017-10-10 | 徐中喜 | A kind of Chinese herbs paste for treating hand-foot-and-mouth disease |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101049337A (en) * | 2007-04-26 | 2007-10-10 | 李柱龙 | Medication for curing furuncle, sore, and carbuncle, and preparation method |
| CN101199579A (en) * | 2007-07-31 | 2008-06-18 | 秦英福 | Medicament for treating aphtha |
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2013
- 2013-07-11 CN CN201310290959.9A patent/CN103340967B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101049337A (en) * | 2007-04-26 | 2007-10-10 | 李柱龙 | Medication for curing furuncle, sore, and carbuncle, and preparation method |
| CN101199579A (en) * | 2007-07-31 | 2008-06-18 | 秦英福 | Medicament for treating aphtha |
Non-Patent Citations (1)
| Title |
|---|
| 冯日萍: "中药清热生肌散治疗复发性口疮的临床观察", 《广东牙病防治》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107233448A (en) * | 2017-07-07 | 2017-10-10 | 徐中喜 | A kind of Chinese herbs paste for treating hand-foot-and-mouth disease |
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