CN103316135B - Traditional Chinese medicine preparation for treating scar formed by restoring skin wound and preparation method thereof - Google Patents

Traditional Chinese medicine preparation for treating scar formed by restoring skin wound and preparation method thereof Download PDF

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CN103316135B
CN103316135B CN201310202183.0A CN201310202183A CN103316135B CN 103316135 B CN103316135 B CN 103316135B CN 201310202183 A CN201310202183 A CN 201310202183A CN 103316135 B CN103316135 B CN 103316135B
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parts
preparation
chinese medicine
skin
cicatrix
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CN103316135A (en
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宋长生
宋金路
宋银路
陈文韬
周瑞
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Abstract

The invention discloses a traditional Chinese medicine preparation for treating scar formed by restoring skin wound and a preparation method thereof, wherein the traditional Chinese medicine preparation by the following traditional Chinese medicine components in proportion: raw rhubarb, korean aconite roof, muscardine silkworm, equisetum, laminaria japonica, kosam seeds, dark plum, bright pink flower seed, pangolin, polygonumchinensis, gotu kola, Chinese prickly ash, desmodium triquetrum, mulberry leaf, and licorice, which make synergism. The traditional Chinese medicine preparation is externally used on a scar part, and can make effects of stasis-breaking, blood stasis dispersion, hardness softening, binds dissipating, toxin expelling, itching relieving, softening and scar removing. The traditional Chinese medicine preparation is directly externally used, and by selectively attacking unnormal scar tissues, enables proliferative capillary vessel net to atrophy, enables blood and nutrition of degenerative fibrotic tissues to be obviously reduced, thereby not only protecting the current epithelial tissues from being damaged, but also making the epithelial tissues and tissues like elastic fiber multiply and reproduce, and enabling the elasticity of the skin tissues to recover; and the traditional Chinese medicine preparation enables the violet red and red disease skin colors of the scar tissues to recover to an original normal skin color, enables hair follicles and original appendages of the skin to be restored and reproduced, and recovers its functions.

Description

The ulotic Chinese medicine preparation of skin trauma shape and preparation method are repaired in treatment
Technical field
The invention belongs to technical field of Chinese medicines, be specifically related to one and treat ulotic Chinese medicine preparation of reparation skin trauma shape and preparation method thereof.
Background technology
Slight skin trauma belongs to epidermis injury, by basal cell hyperplasia, divide a word with a hyphen at the end of a line, flap coverage, gradually after healing, generally without cicatrix or only have slight cicatrization.When undermining corium, wound is deep to lamina reticularis, the endotheliocyte of blood capillary in wound surface, and to sludged blood internal migration,, there is blood capillary, fibroblast proliferation breeding in the new blood capillary forming of growing into, forms granulation tissue.When collagen fiber occur, there is fibrosis in granulation tissue, forms scar tissue gradually., there is scleroma in cicatrix rough surface, color is light red gradually scarlet, the pain of slightly itching.Along with passage of time, form hypertrophic cicatrix.Cicatrix surface is rough and uneven in surface, gage distortion, and the scar tissue that exceeds skin is thick reaches several millimeters, and quality is hard, lacks flexibility, and color and luster becomes purplish redly from scarlet, and blood capillary appears.Cicatrix position, at juxtra-articular, as cicatricial contracture, also occurs that joint deformity causes dysfunction.When cicatrix continues hypertrophy, invade normal surrounding tissue, cicatrization boundary has exceeded initial damage range, occurs keloid.The appearance of cicatrix be the normal phenomenon of healing after body tissue damage, but excessive scar hyperplasia there will be pruritus, hypodynia.The cicatrix of face also can cause heavy psychological burden and huge misery to patient, especially, near the hypertrophic cicatrix of limbs joint, occurs that cicatricial contracture easily causes the dyskinesia, affects patients ' life quality.
Motherland's medical science diagnosis and treatment cicatrix is with a long history, as the Song dynasty " Taiping Royal Prescriptions go out all sides of cicatrix " " husband cicatrix person; be all wind heat poison, be internal organs, rush in muscle, be born in skin ulcer rash; and skin ulcer is more; and poison is not yet entirely loose, therefore though scab falls, its scar is especially dark; or concavo-convex meat rises, should with detoxicating go out scar drug application here.”。At present, Traditional Chinese Medicine experts, the scholar of research cicatrix think that the formation of cicatrix is in patient's wound recovery from illness process more, and positive QI-insufficiency, residual poison are unclean, QI and blood is retarded by silt, in addition due to congenital factors, skin interspaces of skin and muscles being loose, nutritional disorder, the excessive exopathogen of wind, invasion and attack skin.In treatment, by folk prescription, the proved recipe in past develop into into gradually side, compound recipe is applied to clinical, part plays to be controlled scar hyperplasia and reduces twinge, hypodynia, pruritus, extend body reinventing the phase scar repairing, changing cicatrix color, make it to move closer to the normal colour of skin and dwindle cicatrix scope aspect, clinical effectiveness is very unobvious.
Summary of the invention
The inventor uses traditional Chinese medical herbal treatment burn and scald more than 30 years, endeavour the treatment of exploratory development burn, curing in tens thousand of routine fire victims' therapeutic process, from allowing most of fire victim be down to minimum aspect without cicatrix with scar formation rate, accumulate certain successful experience.In long-term clinical position, find that some Chinese medicine has significantly except cicatrix effect in clinical practice.After being inspired, from Fuzheng Paidu, blood stasis dispersing and fresh blood promoting, hard masses softening and resolving, dispelling wind is antipruritic starts with, use Chinese medicine dialectical method, dissect synulotic etiology and pathology, and combine with new development, the new method of the cicatrix research of modern medicine, from adjusting the dosage of medicine compatibility, to the increase and decrease of Chinese medicine screening, constantly research changes newly, has significantly improved the clinical effectiveness for the treatment of cicatrix.
Through protracted and unremitting efforts, exploratory development repeatedly, updates and improves the clinical efficacy for the treatment of cicatrix externally used medicine, has finally completed the present invention in the present invention, has found the treatment that curative effect is given prominence to more to repair the Chinese medicine preparation of cicatrix.So far, also do not find relevant report of the present invention.For this reason, the object of this invention is to provide one and treat the ulotic Chinese medicine preparation of reparation skin trauma shape, utilize the direct external of the present invention, by optionally attacking abnormal scar tissue, make the capillary network atrophy of hypertrophy, blood, the nutrition supply of the fibrosis tissue of degeneration are obviously reduced, impel hypertrophy to protrude scar tissue atrophy, decomposition, absorption, metabolism, not only protected existing epithelial tissue injury-free, but also make the procreation of the tissue such as epithelial tissue and elastic fiber newborn, the elasticity of skin histology is restored; Make that scar tissue is purplish red, the sickly skin color of redness of the skin or complexion, return to the original normal colour of skin, make the hair follicle of skin and original accessory organ is repaired and newborn, and recover the functions such as metabolism such as its defence, absorption, perspire.
Another object of the present invention is to provide the preparation method of this Chinese medicine preparation.
To be inventor get through long-term exploratory development, clinical practice, summary for the morphological element of medicine of the present invention, consumption, the component of each group in following weight compatibility, ratio range, competence exertion optimum curative effect:
2.5~12.5 parts of Radix Et Rhizoma Rhei, 2.5~12.5 parts of Radix Aconiti Coreanis, 2.5~12.5 parts of Herba Equiseties Hiemalis, 2.2~10.5 parts of Bombyx Batryticatus, 1.8~9.5 parts of Thallus Laminariae (Thallus Eckloniae)s, 2.2~10.5 parts of Fructus Bruceaes, 1.5~7.5 parts of Fructus Mumes, 1.5~7.5 parts of water tinctorius seeds, 1.5~7.5 parts of Squama Manis (processed), 1.5~7.5 parts of Herb Polygoni Chinensis'ss (another name Herba Polygoni cymosi), 1.5~7.5 parts of Herba Centellaes, 0.9~4.5 part, Pericarpium Zanthoxyli, 1.2~6.2 parts of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s, 1.2~6.2 parts, Folium Mori, 1.2~6.2 parts, Radix Glycyrrhizae.
For reaching above-mentioned another object, treatment of the present invention is repaired the ulotic Chinese medicine preparation of skin trauma shape and is comprised water preparation and unguentum, water preparation and unguentum are used in conjunction with, best results, the preparation method of its water preparation is: the various Chinese medicine of compatibility proportioning that claims accurate above-mentioned weight, mix evenly, then after being coarse powder with medicinal pulverizer pulverizing, take 1000 grams, pack in the glass device bottle that can hold 10 kilograms, add again 55 ° of above Chinese liquor 6000~6300ml, seal, deposit one month at the indoor seasoning place that is placed on 8 °~20 °, every seven days, soaked medicine is stirred and stirred evenly once later, the medicinal liquid soaking is filtered by three layers of fine cloth, gained filtering liquid medicine is poured clean shelf bottle sealing 15 days again into, treat its natural sedimentation, again medicinal liquid is filtered through five layers of fine cloth, leach the about 5000ml of medicinal liquid that accounts for 20 ﹪ containing pure medicine, seal for subsequent use,
The preparation method of its unguentum is: above-mentioned water preparation is mixed according to the ratio of 10~20ml:20~40g with emulsifiable paste matrix, stir and get final product to such an extent that the ulotic Chinese medicinal ointment of skin trauma shape is repaired in treatment.
The Chinese medicine of compatibility of the present invention: Radix Et Rhizoma Rhei, Radix Aconiti Coreani, Bombyx Batryticatus, Herba Equiseti Hiemalis, Thallus Laminariae (Thallus Eckloniae), Fructus Bruceae, Fructus Mume, water tinctorius seed, Squama Manis, Herba Polygoni cymosi, Herba Centellae, Pericarpium Zanthoxyli, Herba Desmodii Triquetri (Herba Tadehagi Triquetri), Folium Mori, Radix Glycyrrhizae.Make the Chinese medicine of institute's proportioning through combination, produce and be satisfied with synergism, use cicatrix affected part outward, embody removing blood stasis, hard masses softening and resolving, expelling toxin and relieving itching, the clinical effectiveness of the soft and moist scar that disappears.Radix Et Rhizoma Rhei: rush down lower removing blood stasis with potent drugs, removing food stagnancy scale removal." book on Chinese herbal medicine justice ": Radix Et Rhizoma Rhei " go deep into blood system, broken without heavily fortified point, cleanse dirty, have the merit of ploughing up the courtyard and destroy the hide-outs, " " Chinese medicine voluminous dictionary " choosing side (21): " smooth heavily fortified point side " " control and scald that fire is bright hinders, village Radix Et Rhizoma Rhei, life is ground, sweet tune, not only control bitterly, again and the scar of going out ".Modern medicine research, coarse powder extract has destruction to the undesired tissue of body, and the growth of energy inhibition tumor cell.The inventor finds the external of Radix Et Rhizoma Rhei compatibility in treatment cicatrix process, has promoting blood circulation and breaking stagnation, softening cicatrix, recovers skin elasticity, promotes epithelial cell new life's effect.Aconiti koreani,radix, eliminates the phlegm by wet, the kind wind of allowancing for bark." Japan hanako materia medica ": " ... women's head-ornaments cicatrix, enters face fat and uses; " " book on Chinese herbal medicine is newly organized ": " among Radix Et Rhizoma Rhei, can go the stagnant and logical stasis of blood ... external treatment is with the scar of going out, " Bombyx Batryticatus: Xin Xianping, the phoenix spasmolytic of dispelling, dissipating phlegm and resolving masses; " Bencao Jingshu ": " Bombyx Batryticatus: Xin Wen enters lung, all wind of peeling skin, therefore can go out black Shao-and all skin ulcer cicatrixs." Herba Equiseti Hiemalis, wind-dispelling heat-dissipating expelling pathogenic factors from muscles, nebula removing; " beautiful Chinese catalpa medicine solution ": " flat skin infection swollen hard, " " book on Chinese herbal medicine justice ": " removing mass is stagnant, all wears down use of having a surplus also, " thus more than four medicines be monarch.Thallus Laminariae (Thallus Eckloniae) is salty-cold, the capable water of softening the hard mass." Bencao Jingshu ": " salty can softening the hard mass, its property relaxing the bowels with lubricant drugs, cold can heat extraction eliminating stagnation; just salty can softening the hard mass merit also " in " traditional Chinese medical science voluminous dictionary " Thallus Laminariae (Thallus Eckloniae) " iodide enter after tissue and blood; still can make pathological product, as inflammation exudate absorbs, and make ill tissue collapse and dissolving." Fructus Bruceae: heat clearing away, removing dampness and killing parasites, removing toxic substances.Control wart tumor, except proud flesh." ginseng west record in inner feelings " " Fructus Bruceae is apt to cooling blood for hemostasis, and holding concurrently can blood stasis dispersing and fresh blood promoting." find in inventor's clinical practice, this product, to selectively attack function of abnormal histiocyte, can be blocked the utilization of undesired histiocyte to nutrient substance, makes its degenerative change.Fructus Mume: property acid temperature " herbal classic " " remove blue or green melanotic nevus, dislike meat, " " Chinese medicine voluminous dictionary " " control psoriasis, bulbar conjunctiva polyp, " " book on Chinese herbal medicine is looked for the truth " " enter dead flesh, evil meat is disliked nevus and is removed." water tinctorius seed: salty-cold sweet flat, repercussive removing mass, invigorating spleen to remove dampness, " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " year dark heavily fortified point that disappears is long-pending ".Squama Manis: wear hard removing blood stasis with potent drugs, attack the scleroma that disappears.It is more than ministerial drug.Herba Polygoni cymosi; Dampness removing toxin expelling, except skin wind heat pruritus.Holy Benevolent Prescriptions: " 60 grams of raw Oleum sesami of levigation of Herba Polygoni cymosi dress in skin ulcer, go out as degree taking scar." Herba Centellae: subduing swelling and detoxicating." herbal classic " " main skin is red, fever of the body." clinical discovery this product has repair to skin injury, and can change the colour of skin, promotes growth and the recovery of Skin Cell and hair follicle, also have toxin expelling and dissolve the effect of skin surface antibacterial; Pericarpium Zanthoxyli: dispersing cold for relieving pain, removing dampness and detoxicating." Bencao Jingshu " " loosing the interspaces of skin and muscles, exopathogen goes out from skin." " herbal classic " " by the dead flesh of joint skin." " Treatise on Dietetic Therapy " " scar of going out, lower milk." inventor finds in the time that compatibility Pericarpium Zanthoxyli is controlled cicatrix, this product has the effect of the antipruritic and softening stiff tissue of significant dispelling wind.Compatibility application, can make cicatrix color and luster by purplish red, crimson disappearance, returns to the normal colour of skin, can correct again flavour of a drug.Make the pungent cool fragrance of medicinal liquid.Herba Desmodii Triquetri (Herba Tadehagi Triquetri): clearing away heat-damp and promoting diuresis, toxin expelling pain relieving, except scleroderma, controls trace and itch.Folium Mori: table is walked in dispelling wind lung heat clearing." traditional Chinese medical science voluminous dictionary ": " control the inferior limb elephatiasis, can make suffering limb lower limb enclose and dwindle, thinning of skin, subcutaneous tissue is soft, and subjective symptoms disappears." be adjuvant drug above.Radix Glycyrrhizae: walk 12 warps, separate poison of drug and the property of medicine that is in harmonious proportion, delay middle pain relieving and soft and moist skin.Treat harder scar tissue compatibility Radix Glycyrrhizae, found that Radix Glycyrrhizae has can make stiff organization softening, skin surface is moistened smooth, therefore for making medicine.
The alcohol leaching of Chinese medicine proportioning compatibility of the present invention goes out water formulation, and production process is free from environmental pollution, clean health; The preparation color and luster leaching, reddish brown transparent, without precipitation, haze-free; Direct spraying is in cicatrix position, sanitation and hygiene, and Xin Xiang is nice and cool; Can hard masses softening and resolving, the blood stasis dispelling scar reducing swelling and alleviating pain that disappears, dispelling wind is controlled and is itched; Paste formulation is moist, pungent cool delicate fragrance; The foster profit scar of dispelling is not irritated, and skin is comfortable not sticky, and heat clearing away toxin expelling is non-stimulated; Water preparation and unguentum are used alternatingly.
Chinese medicine preparation of the present invention, protrudes skin patient mainly for hypertrophic cicatrix.According to human body skin, weak acid is absorbed to good feature, by this example of compatibility of drugs, make made medicinal liquid and unguentum be faintly acid, make penetrating power faster, rapider.Hypertrophic cicatrix is repaired in treatment, and the surface that adopts the direct disperse of spraying and unguentum directly to smear scar tissue, then gently by soft, after sprayed medicine is all absorbed, spray again medicine and smear medicine, then by soft, medication is by soft 3 times repeatedly, 3 times is treatment 1 time, and every day, repairing and treating 3 times, 1~2 month was 1 course for the treatment of.
This medicine energy rapid osmotic, through epidermis and skin corium, is used and plays blood circulation promoting and blood stasis dispelling in 15~20 days, improves microcirculatory effect, makes Accretive Extensions newly form capillary network atrophy, and blood and the nutrition supply of fibrosis scar tissue cell are reduced gradually.Scar tissue shows color and is shoaled by purplish red, crimson, thin out, and sufferings disappear, and return to the normal colour of skin.Use this product 1~2 month, show by medicine and wear down hard amassing, the effect of blood stasis-eliminating and stagnation-dissipating, to abnormal fibrosis scar tissue cell, carry out targeted attack, make stiff, coarse scar tissue collapse dissolving, differentiation, absorption and the metabolism thickening, thicken several millimeters, stiff coarse, inelastic scar tissue and bounce back gradually, scope is dwindled, the lubricious and high resilience of stiff scar tissue attenuation, the softness that flattens, becomes.The interim this product that uses is after 3~4 months, and significant change appears in cicatrix position, and original normal tissue cell is activated, the newborn normal structures such as substrate epithelial cell, elastic fibers, acantholysis cell, division growth is divided a word with a hyphen at the end of a line, and promotes degraded, promote to reinvent to change structure, make metabolic function more active.Show that the treat position QI and blood of repairing is full, color and luster Rong Run, the colour of skin is tending towards normally, muscular tissue elastic return, after the repairing and treating of 3 courses for the treatment of, scar tissue disappears substantially, and there is pore hair in skin.And show the metabolic functions such as perspire and recover gradually normal.All burns, hot water deep fat is scalded, chemical cautery, dacron, the contour hot liquid of the Colophonium hypertrophic cicatrix forming of burn, wound, the hypertrophic cicatrix that operation forms, the cicatrix of formation after dermatosis recovery from illness, all available this product external repairing and treatings.The old cicatrix that a variety of causes is caused also has obvious effect.Clinical practice proves, this product is heat clearing away toxin expelling both, hard masses softening and resolving, and cicatrix is controlled in detumescence, controls again pain and controls and itch, and Rong Run nourishes skin, the normal function of recovery skin.Compared with prior art, pure Chinese medicinal preparation of the present invention, medical expense is low, has both controlled hypertrophic cicatrix, controls again old cicatrix, and produces effect certainly.Advantage safely and effectively, is worthy of popularization.
Chinese medicine preparation of the present invention, carries out repairing and treating mainly for hypertrophic cicatrix, and clinical effectiveness and Heterosis are in the following aspects: 1, pure Chinese medicinal preparation, nonhazardous, non-stimulated, repairing and treating cicatrix 237 examples, skin allergy occurs none example and poison is paid effect, and any position has cicatrix all can use.2, medicine source abundance, single clear between technique, price is low, and the economic condition of general family all can be accepted repairing and treating.3, easy to use, clean health, patient position used is comfortable, not sticky, does not pollute clothing, the effect that favourable observation is clinical and progress.4, the short-term response of this product treatment hypertrophic cicatrix energy, especially change the sickly skin color of cicatrix for 15~20 days, and crimson color, aubergine disappear, and return to the original normal colour of skin.And can treat scar tissue and meet hot and cold, the noxious dampness pathogen allergy that seasonal climate changes, can make the symptom such as eczema, pruritus thoroughly disappear.5, this product treatment hypertrophic cicatrix, can demonstrate interim effect.Use this product 1~2 month, the softness that make stiff scar tissue attenuation, flattens, becomes is flexible.Use after 3~4 months the position of repairing for the treatment of, color and luster Rong Run.The accessory organ of skin recovers metabolic function gradually, and after 3 courses for the treatment of, scar tissue disappears substantially.6, the present invention had both controlled hypertrophic cicatrix, controlled again old cicatrix, and was the repairing and treating in per stage, had embodied the clinical effectiveness in per stage.
Detailed description of the invention
The present invention is through repeated screening clinical verification, and nonhazardous is non-stimulated, pure Chinese medicinal preparation.Medicinal raw material of the present invention, adds 55 ° of above Chinese liquor (being advisable with high-quality grain wine) by following embodiment, and filtered medicinal liquid is respectively charged in different size (if volume is 30ml, 50ml, 75ml) watering can; Above-mentioned water preparation is mixed homogeneously and modulated unguentum with emulsifiable paste matrix.When clinical use, Direct spraying and be applied in cicatrix position.
Character: the alcohol extract state preparation of Chinese medicine proportioning compatibility, reddish brown transparent, without precipitation, haze-free, water preparation and unguentum be pungent cool delicate fragrance all, volatile; Unguentum color: HUANGBAI(sic), bright, smooth exquisiteness.
1: clinical practice proves, this product is by removing blood stasis, hard masses softening and resolving, and expelling pathogenic factors from the exterior dispelling wind is antipruritic, clearing away heat and promoting diuresis toxin expelling, rapid permeability skin surface, through skin corium and subcutaneous tissue.The stiff scar tissue thickening is dissolved in targeted attack, collapse, and can stop and reduce blood and the nutrition supply of fibrosis tissue, make it the stiff scar tissue attenuation thickening, flatten, the softness becoming is lubricious flexible, the position of repairing for the treatment of, color and luster Rong Run, by adhering to use the course for the treatment of, scar tissue disappears substantially, and the accessory organ of skin recovers metabolic function gradually.2: because this product has and suppresses and killing action various skin fungus, staphylococcus aureus, escherichia coli, bacillus pyocyaneus etc., therefore also have good anti-inflammation, reducing swelling and alleviating pain itching-relieving action.3: because this product it be unclear that the effect of anemia of pregnant woman embryonal tissue, anemia of pregnant woman's forbidding; Use this product may have delactation functions in age of sucking, can select and use later age of sucking.4: external this product had not been found allergy and poisoned reaction.
Function cures mainly: softening hardness and resolving stasis, and the eliminating stagnation scar that disappears, skin protection is supported and is defended, expelling toxin and relieving itching.Treatment fire burn, hot water deep fat is scalded, chemical cautery, the hypertrophic cicatrix that dacron, the contour hot liquid burn of Colophonium form, wound, the hypertrophic cicatrix that operation forms, the cicatrix forming after dermatosis recovery from illness.
Usage: the surface that adopts the direct disperse of spraying and unguentum directly to smear scar tissue, then gently by soft, wait making sprayed water agent and smearing after the whole absorptions of paste medicine, spray again medicine, be coated with cream, by soft, repeatedly spray medicine and smear medicine by soft 3 times again, is for 3 times treatment 1 time, every day, repairing and treating 3 times, 1~2 month was 1 course for the treatment of.
Points for attention: this product can not be used as giving anti-cicatrix during 1 wound, fire victim's treatment; 2 various cicatrix wound surface fester, ulcer person is forbidden this product, ban use of anemia of pregnant woman and age of sucking this product; 3 this product are avoided with other skin moistening category, the scar of dispelling class and are combined use; 4 external curings are repaired between cicatricial phase, the pungent stimulation food of fasting; 5 this product are volatile, should ward off the shady and cool dry place of light storage, with rear sealing preservation; 6 because this product contains micro-ethanol, used time Fire Hazard Area.
Specification: water preparation 30ml/ bottle, 50ml/ bottle, 75ml/ bottle; Unguentum 30g/ bottle, 50g/ bottle, 70g/ bottle.
This Chinese medicine preparation effect duration: 2 years.
Product of the present invention uses through 230 many cases cicatrix patients, more than effective percentage reaches 98 ﹪.
It is to be made up of the crude drug of following weight portion that the ulotic Chinese medicine preparation of skin trauma shape is repaired in treatment of the present invention:
2.5~12.5 parts of Radix Et Rhizoma Rhei, 2.5~12.5 parts of Radix Aconiti Coreanis, 2.5~12.5 parts of Herba Equiseties Hiemalis, 2.2~10.5 parts of Bombyx Batryticatus, 1.8~9.5 parts of Thallus Laminariae (Thallus Eckloniae)s, 2.2~10.5 parts of Fructus Bruceaes, 1.5~7.5 parts of Fructus Mumes, 1.5~7.5 parts of water tinctorius seeds, 1.5~7.5 parts of Squama Manis (processed), 1.5~7.5 parts of Herb Polygoni Chinensis'ss (another name Herba Polygoni cymosi), 1.5~7.5 parts of Herba Centellaes, 0.9~4.5 part, Pericarpium Zanthoxyli, 1.2~6.2 parts of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s, 1.2~6.2 parts, Folium Mori, 1.2~6.2 parts, Radix Glycyrrhizae.
The present invention adopts preparation method: treatment of the present invention is repaired the ulotic Chinese medicine preparation of skin trauma shape and comprised water preparation and unguentum, water preparation and unguentum are used in conjunction with, best results, the preparation method of its water preparation is: the various Chinese medicine of compatibility proportioning that claims accurate above-mentioned weight, mix evenly, then after being coarse powder with medicinal pulverizer pulverizing, take 1000 grams, pack in the glass device bottle that can hold 10 kilograms, add again 55 ° of above Chinese liquor (being advisable with high-quality grain wine) 6000~6300ml, seal, deposit one month at the indoor seasoning place that is placed on 8 °~20 °, every seven days, soaked medicine is stirred and stirred evenly once later, the medicinal liquid soaking is filtered by three layers of fine cloth, gained filtering liquid medicine is poured clean shelf bottle sealing 15 days again into, treat its natural sedimentation, again medicinal liquid is filtered through five layers of fine cloth, leach the about 5000ml of medicinal liquid that accounts for 20 ﹪ containing pure medicine, seal for subsequent use, then it can be held to the mini zone shower nozzle watering can of 30ml, 50ml, 75ml, with after the alcohol-pickled sterilization of 75 ﹪, above-mentioned filtered medicinal liquid is respectively charged in different size (if holding 30ml, 50ml, 75ml) watering can, and labelled, indicate and produce and the bottling date, major function etc., are placed on dry, keep away humidity, 5~20 ° save backup with interior.
The preparation method of its unguentum is: above-mentioned water preparation is mixed according to the ratio of 10~20ml:20~40g with above-mentioned emulsifiable paste matrix, stir, then it can be held to the wide-mouth sub-bottling of 30g, 50g, 70g, with after the alcohol-pickled sterilization of 75 ﹪, above-mentioned hybrid medicine is respectively charged in different size (if holding 30g, 50g, 70g) wide-mouth sub-bottling, can be made into described treatment and repair the ulotic Chinese medicinal ointment of skin trauma shape; And labelled, indicate and produce and the bottling date, major functions etc., are placed on dryly, keep away humidity, and 5~20 ° save backup with interior.
Above-mentioned emulsifiable paste matrix plays water conservation moisturizing in described unguentum, moistens the effect of glabrous skin, and the effective ingredient of medicine can fully be absorbed by skin; On market, all there is sale emulsifiable paste matrix.
embodiment 1:
It is to be made up of the crude drug of following weight portion that the ulotic Chinese medicine preparation of skin trauma shape is repaired in treatment of the present invention:
2.5 parts of Radix Et Rhizoma Rhei, 2.5 parts of Radix Aconiti Coreanis, 2.5 parts of Herba Equiseties Hiemalis, 2.2 parts of Bombyx Batryticatus, 1.8 parts of Thallus Laminariae (Thallus Eckloniae)s, 2.2 parts of Fructus Bruceaes, 1.5 parts of Fructus Mumes, 1.5 parts of water tinctorius seeds, 1.5 parts of Squama Manis (processed), 1.5 parts of Herb Polygoni Chinensiss, 1.5 parts of Herba Centellaes, 0.9 part, Pericarpium Zanthoxyli, 1.2 parts of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s, 1.2 parts, Folium Mori, 1.2 parts, Radix Glycyrrhizae.
The present invention adopts preparation method: treatment of the present invention is repaired the ulotic Chinese medicine preparation of skin trauma shape and comprised water preparation and unguentum, water preparation and unguentum are used in conjunction with, best results, the preparation method of its water preparation is: the various Chinese medicine of compatibility proportioning that claims accurate above-mentioned weight, mix evenly, then after being coarse powder with medicinal pulverizer pulverizing, take 1000 grams, pack in the glass device bottle that can hold 10 kilograms, add again 55 ° of above Chinese liquor (being advisable with high-quality grain wine) 6000~6300ml, seal, deposit one month at the indoor seasoning place that is placed on 8 °~20 °, every seven days, soaked medicine is stirred and stirred evenly once later, the medicinal liquid soaking is filtered by three layers of fine cloth, gained filtering liquid medicine is poured clean shelf bottle sealing 15 days again into, treat its natural sedimentation, again medicinal liquid is filtered through five layers of fine cloth, leach the about 5000ml of medicinal liquid that accounts for 20 ﹪ containing pure medicine, seal for subsequent use.Then it can be held to the mini zone shower nozzle watering can of 30ml, 50ml, 75ml, with after the alcohol-pickled sterilization of 75 ﹪, above-mentioned filtered medicinal liquid is respectively charged in different size (if holding 30ml, 50ml, 75ml) watering can, and labelled, indicate and produce and the bottling date, major function etc., are placed on dry, keep away humidity, 5~20 ° save backup with interior.
The preparation method of its unguentum is: above-mentioned water preparation is mixed according to the ratio of 10~20ml:20~40g with above-mentioned emulsifiable paste matrix, stir, then it can be held to the wide-mouth sub-bottling of 30g, 50g, 70g, with after the alcohol-pickled sterilization of 75 ﹪, above-mentioned hybrid medicine is respectively charged in different size (if holding 30g, 50g, 70g) wide-mouth sub-bottling, can be made into described treatment and repair the ulotic Chinese medicinal ointment of skin trauma shape.
embodiment 2:
It is to be made up of the crude drug of following weight portion that the ulotic Chinese medicine preparation of skin trauma shape is repaired in treatment of the present invention:
5 parts of Radix Et Rhizoma Rhei, 5 parts of Radix Aconiti Coreanis, 5 parts of Herba Equiseties Hiemalis, 4.5 parts of Bombyx Batryticatus, 3.6 parts of Thallus Laminariae (Thallus Eckloniae)s, 4 parts of Fructus Bruceaes, 3 parts of Fructus Mumes, 3 parts of water tinctorius seeds, 3 parts of Squama Manis (processed), 3 parts of Herb Polygoni Chinensiss, 3 parts of Herba Centellaes, 1.8 parts, Pericarpium Zanthoxyli, 2.4 parts of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s, 2.4 parts, Folium Mori, 2.4 parts, Radix Glycyrrhizae.
The preparation method of the present embodiment is with embodiment 1.
embodiment 3:
It is to be made up of the crude drug of following weight portion that the ulotic Chinese medicine preparation of skin trauma shape is repaired in treatment of the present invention:
7.5 parts of Radix Et Rhizoma Rhei, 7.5 parts of Radix Aconiti Coreanis, 7.5 parts of Herba Equiseties Hiemalis, 6.5 parts of Bombyx Batryticatus, 5.4 parts of Thallus Laminariae (Thallus Eckloniae)s, 6.5 parts of Fructus Bruceaes, 4.5 parts of Fructus Mumes, 4.5 parts of water tinctorius seeds, 4.5 parts of Squama Manis (processed), 4.5 parts of Herb Polygoni Chinensis'ss (another name Herba Polygoni cymosi), 4.5 parts of Herba Centellaes, 2.7 parts, Pericarpium Zanthoxyli, 3.6 parts of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s, 3.6 parts, Folium Mori, 3.6 parts, Radix Glycyrrhizae.
The preparation method of the present embodiment is with embodiment 1.
embodiment 4:
It is to be made up of the crude drug of following weight portion that the ulotic Chinese medicine preparation of skin trauma shape is repaired in treatment of the present invention:
9 parts of Radix Et Rhizoma Rhei, 9 parts of Radix Aconiti Coreanis, 9 parts of Herba Equiseties Hiemalis, 8 parts of Bombyx Batryticatus, 7.2 parts of Thallus Laminariae (Thallus Eckloniae)s, 8 parts of Fructus Bruceaes, 6 parts of Fructus Mumes, 6 parts of water tinctorius seeds, 6 parts of Squama Manis (processed), 6 parts of Herb Polygoni Chinensis'ss (another name Herba Polygoni cymosi), 6 parts of Herba Centellaes, 3.9 parts, Pericarpium Zanthoxyli, 4.8 parts of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s, 4.8 parts, Folium Mori, 4.8 parts, Radix Glycyrrhizae.
The preparation method of the present embodiment is with embodiment 1.
embodiment 5:
It is to be made up of the crude drug of following weight portion that the ulotic Chinese medicine preparation of skin trauma shape is repaired in treatment of the present invention:
10.5 parts of Radix Et Rhizoma Rhei, 10.5 parts of Radix Aconiti Coreanis, 10.5 parts of Herba Equiseties Hiemalis, 9 parts of Bombyx Batryticatus, 9 parts of Thallus Laminariae (Thallus Eckloniae)s, 9 parts of Fructus Bruceaes, 7 parts of Fructus Mumes, 7 parts of water tinctorius seeds, 7 parts of Squama Manis (processed), 7 parts of Herb Polygoni Chinensis'ss (another name Herba Polygoni cymosi), 7 parts of Herba Centellaes, 4 parts, Pericarpium Zanthoxyli, 5.5 parts of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s, 5.5 parts, Folium Mori, 5.5 parts, Radix Glycyrrhizae.
The preparation method of the present embodiment is with embodiment 1.
embodiment 6:
It is to be made up of the crude drug of following weight portion that the ulotic Chinese medicine preparation of skin trauma shape is repaired in treatment of the present invention:
12.5 parts of Radix Et Rhizoma Rhei, 12.5 parts of Radix Aconiti Coreanis, 12.5 parts of Herba Equiseties Hiemalis, 10.5 parts of Bombyx Batryticatus, 9.5 parts of Thallus Laminariae (Thallus Eckloniae)s, 10.5 parts of Fructus Bruceaes, 7.5 parts of Fructus Mumes, 7.5 parts of water tinctorius seeds, 7.5 parts of Squama Manis (processed), 7.5 parts of Herb Polygoni Chinensis'ss (another name Herba Polygoni cymosi), 7.5 parts of Herba Centellaes, 4.5 parts, Pericarpium Zanthoxyli, 6.2 parts of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s, 6.2 parts, Folium Mori, 6.2 parts, Radix Glycyrrhizae.
The preparation method of the present embodiment is with embodiment 1.
model case:
Case 1: Wang, female, 42 years old, Han nationality, lived Du Xi village, Du Shu town, Fangcheng County, Henan Province solely western No. 18.Because wound right lower extremity ankle joint and instep are by joint, after recovery, there is hypertrophic cicatrix in May, 2010.Cicatrix scope: 2 ㎝ × 18 ㎝, exceed normal skin 0.3 ㎜, cicatrix is strip, and the cicatrix of pressing is stiff slightly feels pain, lack flexibility, often pruritus, scar red complexion purple is dark.In JIUYUE, 2011 starts to observe after one month with the present invention's scar preparation of dispelling, and the crimson color of cicatrix recovers the normal colour of skin, and micro-pain and pruritus thoroughly disappear.Repair after two courses for the treatment of with the present invention's scar preparation for treating of dispelling, cicatrix scope is dwindled and is become 1 ㎝ × 1.5 ㎝ and 1 ㎝ × 2 ㎝ two small pieces cicatrixs, and the cicatrix that exceeds normal skin is reduced to 0.1 ㎜, the obvious deliquescing of stiff cicatrix.After three courses for the treatment of are repaired in treatment, the affected part of controlling, cicatrix disappears substantially, and elastic return is normal, and soft surface is ruddy, and pruritus thoroughly disappears.
Case 2: Wang, man, 8 years old, Han nationality, lived 9 groups, Ma Zhuan Village, Gu Zhuan shop township, Fangcheng County, Henan Province No. 95.Scald right lower extremity outside because of hot water in February, 2004, occurs hypertrophic cicatrix after healing.Cicatrix scope: 9 ㎝ × 19 ㎝, exceed normal skin 0.2 ㎜, be that irregular lamellar, strip are staggered to be held concurrently mutually.Cicatrix is stiff to lack flexibility, pruritus the cloth many places trace of itching, scar color purple.Observe one month after with the present invention's scar preparation of dispelling in January, 2013, and the crimson color of cicatrix recovers the normal colour of skin, and pruritus disappears.Repair after two courses for the treatment of with the present invention's scar preparation for treating of dispelling, cicatrix scope is dwindled and is become 5 ㎝ × 11 ㎝, and the cicatrix that exceeds normal skin is reduced to 0.1 ㎜, the obvious deliquescing of stiff cicatrix.Observe in the recent period, the affected part of controlling, cicatrix is further dwindled, and approaches normal skin, and elasticity is also recovered normally, and pruritus thoroughly disappears, its clinical effectiveness, family members are very satisfied.Still in continuation repairing and treating.
Case 3: high certain, man, 16 years old, Han nationality, lived in Quan Qiaojizhuan village, Fangcheng County, Henan Province Zhang Lan Mu Zhuan No. 45.Scald back because of hot water in July, 2008, occurs cicatrix after healing.Cicatrix scope: 16 ㎝ × 21 ㎝, exceed normal skin approximately 0.1 ㎜, lack flexibility in the form of sheets, pruritus, scar color is purple dark.Observe one month after with the present invention's scar preparation of dispelling in October, 2012, and cicatrix sickly skin color is recovered the normal colour of skin, and pruritus disappears.With after two courses for the treatment of of this product, cicatrix scope is dwindled and is become 4 ㎝ × 7 ㎝, scar thickness be reduced to 0.02 ㎜ and approach normal, the obvious deliquescing of cicatrix, attenuation.With after three courses for the treatment of of this product, the affected part of controlling, shows pore hair, perspire, etc. metabolic function recover, cicatrix disappears substantially, elastic return is normal, pruritus thoroughly disappears.
Case 4: cattle, man 2 years old, Han nationality, lives in Yang Lou township, Fangcheng County, Henan Province Niu Shilong village Niu Shilong No. 40.Scald left side upper limb elbow joint place because of hot water in July, 2011, occurs more afterwards hypertrophic cicatrix.Cicatrix scope: 8.5 ㎝ × 11 ㎝, exceed normal skin approximately 0.15 ㎜, cicatrix lacks flexibility, and elbow joint motion has slight effect, pruritus, crimson, white scar is held concurrently mutually.In July, 2012, by this product after one month, the sickly skin color that crimson, the white scar of cicatrix is held concurrently mutually reverted to the normal colour of skin, and pruritus disappears.With after two courses for the treatment of of this product, cicatrix scope is dwindled and is become 2 ㎝ × 5 ㎝, and scar thickness is reduced to 0.07 ㎜, the obvious deliquescing of cicatrix.With after three courses for the treatment of of this product, the affected part cicatrix of controlling disappears substantially, and elastic return is normal, and pruritus thoroughly disappears, and shows hair pore, recovers the metabolic functions such as perspire.

Claims (2)

1. the ulotic Chinese medicine preparation of skin trauma shape is repaired in a treatment, it is characterized in that it is to be made up of the crude drug of following weight portion that the ulotic Chinese medicine preparation of skin trauma shape is repaired in described treatment: 2.5~12.5 parts of Radix Et Rhizoma Rhei, 2.5~12.5 parts of Radix Aconiti Coreanis, 2.5~12.5 parts of Herba Equiseties Hiemalis, 2.2~10.5 parts of Bombyx Batryticatus, 1.8~9.5 parts of Thallus Laminariae (Thallus Eckloniae)s, 2.2~10.5 parts of Fructus Bruceaes, 1.5~7.5 parts of Fructus Mumes, 1.5~7.5 parts of water tinctorius seeds, 1.5~7.5 parts of Squama Manis (processed), 1.5~7.5 parts of Herb Polygoni Chinensiss, 1.5~7.5 parts of Herba Centellaes, 0.9~4.5 part, Pericarpium Zanthoxyli, 1.2~6.2 parts of Herba Desmodii Triquetri (Herba Tadehagi Triquetri)s, 1.2~6.2 parts, Folium Mori, 1.2~6.2 parts, Radix Glycyrrhizae, the preparation method of above-mentioned Chinese medicine preparation is:
Described treatment is repaired the ulotic Chinese medicine preparation of skin trauma shape and is comprised water preparation and unguentum, water preparation and unguentum are used in conjunction with, the preparation method of its water preparation is: the various Chinese medicine of compatibility proportioning that claims accurate above-mentioned weight, mix evenly, then after being coarse powder with medicinal pulverizer pulverizing, take 1000 grams, pack in the glass device bottle that can hold 10 kilograms, add again 55 ° of above Chinese liquor 6000~6300ml, seal, deposit one month at the indoor seasoning place that is placed on 8~20 DEG C, and every seven days, soaked medicine is stirred and stirred evenly once, the medicinal liquid soaking is filtered by three layers of fine cloth, gained filtering liquid medicine is poured clean shelf bottle sealing 15 days again into, treat its natural sedimentation, again medicinal liquid is filtered through five layers of fine cloth, leach the medicinal liquid 5000ml that accounts for 20 ﹪ containing pure medicine, seal for subsequent use,
The preparation method of its unguentum is: above-mentioned water preparation is mixed according to the ratio of 10~20ml:20~40g with emulsifiable paste matrix, stir and make the ulotic Chinese medicinal ointment for the treatment of reparation skin trauma shape.
2. the preparation method that skin trauma formation cicatrix Chinese medicine preparation is repaired in treatment as claimed in claim 1, this preparation method is:
Described treatment is repaired the ulotic Chinese medicine preparation of skin trauma shape and is comprised water preparation and unguentum, water preparation and unguentum are used in conjunction with, the preparation method of its water preparation is: the various Chinese medicine of compatibility proportioning that claims accurate above-mentioned weight, mix evenly, then after being coarse powder with medicinal pulverizer pulverizing, take 1000 grams, pack in the glass device bottle that can hold 10 kilograms, add again 55 ° of above Chinese liquor 6000~6300ml, seal, deposit one month at the indoor seasoning place that is placed on 8~20 DEG C, and every seven days, soaked medicine is stirred and stirred evenly once, the medicinal liquid soaking is filtered by three layers of fine cloth, gained filtering liquid medicine is poured clean shelf bottle sealing 15 days again into, treat its natural sedimentation, again medicinal liquid is filtered through five layers of fine cloth, leach the medicinal liquid 5000ml that accounts for 20 ﹪ containing pure medicine, seal for subsequent use,
The preparation method of its unguentum is: above-mentioned water preparation is mixed according to the ratio of 10~20ml:20~40g with emulsifiable paste matrix, stir and make the ulotic Chinese medicinal ointment for the treatment of reparation skin trauma shape.
CN201310202183.0A 2013-05-28 2013-05-28 Traditional Chinese medicine preparation for treating scar formed by restoring skin wound and preparation method thereof Expired - Fee Related CN103316135B (en)

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