CN103316077A - Drug composition for sterilization and itching-relieving - Google Patents
Drug composition for sterilization and itching-relieving Download PDFInfo
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- CN103316077A CN103316077A CN2013102115819A CN201310211581A CN103316077A CN 103316077 A CN103316077 A CN 103316077A CN 2013102115819 A CN2013102115819 A CN 2013102115819A CN 201310211581 A CN201310211581 A CN 201310211581A CN 103316077 A CN103316077 A CN 103316077A
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Abstract
The invention discloses a drug composition for sterilization and itching-relieving. The drug composition comprises, by weight, 2300 to 2500 parts of Vaseline, 370 to 380 parts of dexamethasone acetate, 0.8 to 1.2 parts of cyproheptadine hydrochloride, 4 to 6 parts of vitamin B, 110 to 120 parts of menthol, 110 to 120 parts of salicylic acid, 110 to 120 parts of carbolic acid and 110 to 120 parts of boracic acid. An effective dose of dexamethasone acetate has effects of diminishing inflammation and resisting allergy. An effective dose of cyproheptadine hydrochloride has the effect of resisting allergy. An effective dose of vitamin B has the effect of adjusting human acidity. Effective doses of weak acids such as salicylic acid, carbolic acid and boracic acid have drug effects of sterilization and disinfection. An effective dose of menthol has effects of relieving itching, diminishing inflammation and relieving pain, can produce local cool sense and has the obvious effect of relieving pain. Vaseline has a good lubrication effect, can be used as a solvent, has strong adhesion to effective drugs, and has the obvious effects of lubrication and maintenance.
Description
Technical field
The invention belongs to tcm field, particularly the Chinese medicine of disease such as treatment fungal infection etc.
Background technology
Fungus (fungus) belongs to plant kingdom, Eumycota.It does not have root, stem, leaf structure, thereby can not utilize inorganic matter to carry out photosynthesis, can only seek parasitic life or saprogenesis.Except the unicellular monoid of minority, fungus has branch or unbranched mycelium mostly, can carry out sexual or asexual propagation.Fungus is suitable in moist, warm environment breeding; At aerobic, temperature is suitable and have under the condition of certain humidity, the fungus of flying away in the air is increased.So the allergic generation of fungus also has provincialism and seasonal feature.Generally in summer, particularly intermittent drizzles in the rainy season seasons, the allergic morbidity of fungus increases.But its provincialism and seasonal characteristics are clear and definite unlike pollinosis.For example, in the winter time, superheated room or workshop, particularly humidification, the Air Fungi amount of flying away is also a lot, also can form epidemic peak.Fungal infection mainly is autogenous infection (such as Candida albicans), and exogenous infection (such as aspergillosis) is also arranged, this type of infection and Abwehrkraft des Koepers, and immunity reduces and the bacterium colony imbalance.
What fungal infectious disease was the most common is tinea pedis, beriberi, tinea etc., and the treatment of fungal infection is the difficult problem that medical circle is captured always.The medicine of existing various treatment fungal infection is cures the symptoms, not the disease, and therapeutic effect is not obvious, and relapse rate is high.
Summary of the invention
In view of this, the object of the present invention is to provide a kind of composition of medicine for sterilizing and itch-relieving, this composition of medicine is intended to treat the dermatosiss such as tinea pedis, dermatomycosis.Two of purpose of the present invention is to provide the preparation method of described preparation, and the method program is simple, is suitable for large-scale production.
For achieving the above object, technical scheme of the present invention is: a kind of composition of medicine for sterilizing and itch-relieving, and composed of the following components in effective dose: vaseline, dexamethasone acetate, cyproheptadine hydrochloride, vitamin B6, Mentholum, salicylic acid, carbolic acid, boric acid.
Particularly, composed of the following components by weight:
Further, described composition of medicine is composed of the following components by weight:
The present invention also provides the application of this composition of medicine in the medicine of preparation treatment tinea pedis.
The present invention also provides the application of this composition of medicine in the medicine of preparation treatment fungus tinea.
The present invention also provides the preparation method of this composition of medicine, may further comprise the steps:
A, with dexamethasone acetate, cyproheptadine hydrochloride and vitamin B6 mixed grinding powdering;
B, vaseline is heated to boiling after, stopped heating adds steps A gained mixed-powder in the vaseline and fully immediately and stirs, and when temperature is between 70 ℃-80 ℃, adds successively salicylic acid, carbolic acid and boric acid, and continues to stir;
C, when temperature is between 30 ℃-40 ℃, add Mentholum, cooling gets final product after fully stirring.
Beneficial effect of the present invention is: among the present invention, dexamethasone acetate has antiinflammatory, anti-allergic effects under effective dose; Cyproheptadine hydrochloride has anti-allergic effects under effective dose; Vitamin B6 has the effects such as balance the body acidity under effective dose; The weak acid such as salicylic acid, carbolic acid, boric acid have the pharmacological action of sterilizing under effective dose; That Mentholum has under effective dose is antipruritic, the effect of antiinflammatory, pain relieving, and the part has cool feeling simultaneously, and analgesic effect is obvious; Utilize the good lubrication of vaseline as solvent, effective agent strong adhesion, and lubricating maintenance successful.On probation through the tinea pedis patient, effective percentage 100% of the present invention, cure rate is high, and is rapid-action.
The specific embodiment
Illustrated embodiment is in order better content of the present invention to be described, but is not that content of the present invention only limits to illustrated embodiment.So those of ordinary skill in the art carry out nonessential improvement and adjustment according to the foregoing invention content to embodiment, still belong to protection scope of the present invention.
Embodiment 1 composition of medicine and experiment effect thereof
One, prescription and preparation method thereof
Get raw material by following component and weight: vaseline 2300g; Dexamethasone acetate 380g; Cyproheptadine hydrochloride 0.8g; Vitamin B6 6g; Mentholum 110g; Salicylic acid 120g; Carbolic acid 110g; Boric acid 120g.
Preparation method is:
A, with dexamethasone acetate, cyproheptadine hydrochloride and vitamin B6 mixed grinding powdering;
B, vaseline is heated to boiling after, stopped heating immediately will steps A gained mixed-powder adds in the vaseline and fully and stirs, and when temperature during at 70 ℃, adds successively salicylic acid, carbolic acid and boric acid, and continues to stir;
C, when temperature during at 40 ℃, add Mentholum, cooling gets final product after fully stirring.Described product is gel.
Two, therapeutic effect: year August in June, 2006-2007 above-mentioned finished product is implemented treatment to 60 routine tinea pedis (the most serious patient is the infected more than 10 years), effective percentage 100%, wherein 58 people recovery from illness, cure rate is up to 96.67%.
Embodiment 2 composition of medicine and experiment effect thereof
One, prescription and preparation method thereof
Get raw material by following component and weight: vaseline 2500g; Dexamethasone acetate 370g; Cyproheptadine hydrochloride 1.2g; Vitamin B6 4g; Mentholum 120g; Salicylic acid 110g; Carbolic acid 120g; Boric acid 110g.
Preparation method is:
A, with dexamethasone acetate, cyproheptadine hydrochloride and vitamin B6 mixed grinding powdering;
B, vaseline is heated to boiling after, stopped heating immediately will steps A gained mixed-powder adds in the vaseline and fully and stirs, and when temperature during at 80 ℃, adds successively salicylic acid, carbolic acid and boric acid, and continues to stir;
C, when temperature during at 30 ℃, add Mentholum, cooling gets final product after fully stirring.Described product is gel.
Two, therapeutic effect: year March in January, 2008-2010 above-mentioned finished product is implemented treatment to 108 routine tinea pedis, effective percentage 100%, wherein 101 people recovery from illness, cure rate is up to 93.5%.
Embodiment 3 composition of medicine and experiment effect thereof
One, prescription and preparation method thereof
Get raw material by following component and weight: vaseline 2380g; Dexamethasone acetate 375g; Cyproheptadine hydrochloride 1.0g; Vitamin B6 5.0g; Mentholum 114g; Salicylic acid 114g; Carbolic acid 114g; Boric acid 114g.
Preparation method is:
A, with dexamethasone acetate, cyproheptadine hydrochloride and vitamin B6 mixed grinding powdering;
B, vaseline is heated to boiling after, stopped heating immediately will steps A gained mixed-powder adds in the vaseline and fully and stirs, and when temperature during at 75 ℃, adds successively salicylic acid, carbolic acid and boric acid, and continues to stir;
C, when temperature during at 36 ℃, add Mentholum, cooling gets final product after fully stirring.Described product is gel.
Two, therapeutic effect: in June, 2010-2012 year December, above-mentioned finished product is implemented treatment to 75 routine tinea pedis, effective percentage 100%, wherein 75 people recovery from illness, cure rate is up to 100%.
Explanation is at last, above embodiment is only unrestricted in order to technical scheme of the present invention to be described, although with reference to preferred embodiment the present invention is had been described in detail, those of ordinary skill in the art is to be understood that, can make amendment or be equal to replacement technical scheme of the present invention, and not breaking away from aim and the scope of technical solution of the present invention, it all should be encompassed in the middle of the claim scope of the present invention.
Claims (6)
1. a composition of medicine that is used for sterilizing and itch-relieving is characterized in that: composed of the following components in effective dose: vaseline, dexamethasone acetate, cyproheptadine hydrochloride, vitamin B6, Mentholum, salicylic acid, carbolic acid, boric acid.
2. composition of medicine according to claim 1 is characterized in that, and is composed of the following components by weight:
3. composition of medicine according to claim 2 is characterized in that, described composition of medicine is composed of the following components by weight:
4. the application of each described composition of medicine of claim 1-3 in the medicine of preparation treatment tinea pedis.
5. the application of each described composition of medicine of claim 1-3 in the medicine of preparation treatment fungus tinea.
6. the preparation method of each described composition of medicine of 1-3 is characterized in that: may further comprise the steps:
A, with dexamethasone acetate, cyproheptadine hydrochloride and vitamin B6 mixed grinding powdering;
B, vaseline is heated to boiling after, stopped heating adds steps A gained mixed-powder in the vaseline and fully immediately and stirs, and when temperature is between 70 ℃-80 ℃, adds successively salicylic acid, carbolic acid and boric acid, and continues to stir;
C, when temperature is between 30 ℃-40 ℃, add Mentholum, cooling gets final product after fully stirring.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310211581.9A CN103316077B (en) | 2013-05-31 | 2013-05-31 | Drug composition for sterilization and itching-relieving |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310211581.9A CN103316077B (en) | 2013-05-31 | 2013-05-31 | Drug composition for sterilization and itching-relieving |
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| Publication Number | Publication Date |
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| CN103316077A true CN103316077A (en) | 2013-09-25 |
| CN103316077B CN103316077B (en) | 2014-10-15 |
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| CN201310211581.9A Expired - Fee Related CN103316077B (en) | 2013-05-31 | 2013-05-31 | Drug composition for sterilization and itching-relieving |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104435938A (en) * | 2014-11-18 | 2015-03-25 | 徐莉梅 | Pharmaceutical composition for treating eczema and application of pharmaceutical composition |
| CN104721270A (en) * | 2013-12-20 | 2015-06-24 | 刘艳红 | Medicinal ointment and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN1679605A (en) * | 2005-01-11 | 2005-10-12 | 倪明芝 | Medicine for treating refractory ringworm |
| CN1943581A (en) * | 2006-10-20 | 2007-04-11 | 刘亚军 | External use medicine for treating dermatosis and its preparing method |
| CN101390830A (en) * | 2008-11-12 | 2009-03-25 | 常州市第四制药厂有限公司 | Anarexol cream and preparation method thereof |
-
2013
- 2013-05-31 CN CN201310211581.9A patent/CN103316077B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1679605A (en) * | 2005-01-11 | 2005-10-12 | 倪明芝 | Medicine for treating refractory ringworm |
| CN1943581A (en) * | 2006-10-20 | 2007-04-11 | 刘亚军 | External use medicine for treating dermatosis and its preparing method |
| CN101390830A (en) * | 2008-11-12 | 2009-03-25 | 常州市第四制药厂有限公司 | Anarexol cream and preparation method thereof |
Non-Patent Citations (3)
| Title |
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| 康世杰: "自拟方治疗足癣21例临床体会", 《中国实用乡村医生杂志》 * |
| 徐参: "再谈皮肤病外用药的应用", 《中国农村医学》 * |
| 王周武等: "脚气糊的研制与临床疗效观察", <<贵州医药>> * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104721270A (en) * | 2013-12-20 | 2015-06-24 | 刘艳红 | Medicinal ointment and preparation method thereof |
| CN104435938A (en) * | 2014-11-18 | 2015-03-25 | 徐莉梅 | Pharmaceutical composition for treating eczema and application of pharmaceutical composition |
| CN104435938B (en) * | 2014-11-18 | 2018-01-26 | 徐莉梅 | Treat pharmaceutical composition and its application of eczema |
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| Publication number | Publication date |
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| CN103316077B (en) | 2014-10-15 |
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Granted publication date: 20141015 Termination date: 20180531 |