CN103314985B

CN103314985B - A kind of Pesticidal combination containing pyridalyl and anabasine

Info

Publication number: CN103314985B
Application number: CN201210079881.1A
Authority: CN
Inventors: 张伟
Original assignee: Shaanxi Welch Crop Protection Co Ltd
Current assignee: Shaanxi Yitianfeng Crop Technology Co ltd
Priority date: 2012-03-24
Filing date: 2012-03-24
Publication date: 2016-05-18
Anticipated expiration: 2032-03-24
Also published as: CN103314985A; CN105613561A

Abstract

The invention discloses a kind of Pesticidal combination containing pyridalyl and anabasine, composition contains active components A and active component B, wherein active components A is selected from pyridalyl, active component B is selected from following any one compound: thiacloprid, Diacloden, clothianidin, MTI-446, and the weight ratio of active components A and active component B is 1 ︰ 80 ~ 80 ︰ 1. The present composition can be prevented and treated various pests, and has obvious synergistic effect, has expanded insecticidal spectrum, and various pests is had to greater activity; And reduce agricultural chemicals dosage, reduced the residual quantity of agricultural chemicals on crop, alleviated environmental pollution; To person poultry safety, Environmental compatibility is good, and insect is difficult for developing immunity to drugs.

Description

A kind of Pesticidal combination containing pyridalyl and anabasine

Technical field

The invention belongs to technical field of pesticide, relate to a kind of Pesticidal combination containing pyridalyl and anabasine.

Background technology

Pyridalyl (Pyridalyl) chemical name: 2-[3-[2, the chloro-4-[(3 of 6-bis-, the chloro-2-acrylic of 3-bis-) oxygen base] phenoxy group] propoxyl group]-5-(trifluoromethyl) pyrimidine, molecular formula: C₃₂H₁₄F₃NO₃. Pyridalyl has and the diverse structure of existing pesticide, and the many lepidoptera pests on vegetables and cotton are had to remarkable insecticidal activity. There is the effect of tagging with stomach toxicity simultaneously, lepidoptera pest is had to original preventive effect, thrips is also demonstrated to certain activity, and pyridalyl is very little on various arthropodan impacts, so it is expected to become an effective instrument in integrated pest management.

Diacloden (Thiamethoxam) chemical name: 3-(the chloro-1,3-thiazoles-5-of 2-ylmethyl)-5-methyl isophthalic acid, 3,5-oxadiazines-4-base fork (nitro) amine, molecular formula: C₈H₁₀ClN₅O₃S, Diacloden is a kind of second generation nicotinoids high-efficient low toxicity insecticide of brand new, insect is had stomach toxicity, is tagged and systemic activity, for foliar spray and soil root irrigation. After its dispenser, rapidly by interior suction, and be transmitted to the each position of plant, sucking pest is had to good preventive effect as aphid, plant hopper, leafhopper, aleyrodid etc.

Thiacloprid (Thiacloprid) chemical name: (3-((6-chloro-3-pyridyl base) methyl)-1,3-thiazoles quinoline-2-subunit) cyanamide, molecular formula: C₁₃H₅N₄SCl, the former medicine of thiacloprid is developed cooperatively by Bayer Bitterfeld GmbH Nong Hua company and Japanese Bayer Nong Hua company, is novel chloro nicotinic insecticide; The mechanism of action of thiacloprid and other conventional pesticides are different. Its Main Function engages caudacoria in insect nerve, by being combined with nAChR, and interference insect nervous system normal conduction, cause the obstruction of neural channel, cause a large amount of accumulation of acetylcholine, thereby make insect exaltation, whole body spasm, paralysis and dead. There is stronger interior suction, tag and stomach poison function, there is no cross resistance with common insecticides as pyrethroid, organic phosphates and carbamates, thereby can be used for resistance management.

Clothianidin (clothianidin) chemical name: (E)-1-(the chloro-1,3-thiazoles-5-of 2-ylmethyl)-3-methyl-2-2-nitroguanidine, molecular formula: C₁₀H₁₉O₆PS₂, clothianidin is a kind of pesticide in anabasine, is the novel pesticide of a class highly effective and safe, high selectivity, its effect is similar with nAChR, have tag, stomach toxicity and systemic activity. Be mainly used on paddy rice, vegetables, fruit tree and other crops anti-ly eliminating aphis, the pesticide of Semiptera, coleoptera, Diptera and some Lepidoptera class pest such as leafhopper, thrips, plant hopper, there is efficient, wide spectrum, consumption is few, toxicity is low, the drug effect lasting period long, to crop without poisoning, use safety, with conventional pesticide without advantages such as cross resistances, having remarkable interior suction and osmosis, is the another kind that substitutes high malicious organophosphorus pesticide. Its novel structure, special, performance is more excellent compared with traditional nicotinic insecticide, and large-scale insecticide variety likely becomes international.

MTI-446 (dinotefuran) chemical name: 1-methyl-2-nitro-3-(tetrahydrochysene-3-furfuryl) guanidine; (EZ)-(RS)-1-methyl-2-nitro-3-(tetrahydrochysene-3-furfuryl) guanidine; N-methyl-N'-nitro-N''-[(tetrahydrochysene-3-furans) methyl] guanidine, molecular formula: C₇H₁₄N₄O₃, MTI-446 is the third generation nicotinic insecticide of Mitsui chemical company exploitation. The chemical constitution of itself and existing nicotinic insecticide is far from each other, and chloro-pyridine base, chloro thiazolyl before its tetrahydrofuran base has replaced, containing halogen. Meanwhile, also different with nicotine at aspect of performance, so people are referred to as " furans nicotine " at present.

But in the real process of agricultural production, the problem that pest control the most easily produces is the generation of pest resistance to insecticide. Different cultivars composition carries out composite, is the very common method of control resistant insect. Heterogeneity is carried out composite, according to practical application effect, judge certain composite be synergy, add and or antagonism. In most cases, the composite effect of agricultural chemicals is all additive effect, really have a synergistic effect composite seldom, especially synergistic effect very obviously, co-toxicity coefficient very high composite just still less. Through inventor research, find after pyridalyl and thiacloprid, Diacloden, clothianidin, MTI-446 is composite to produce good synergistic effect, and not yet open about the composite relevant report of pyridalyl and thiacloprid, Diacloden, clothianidin, MTI-446.

Summary of the invention

Resistance that the long-term use of pyridalyl single dose may bring occurs, degradation problem under drug effect, and the Pesticidal combination that the present invention proposes contains active components A, active component B, and appropriate surfactant and carrier.

A kind of Pesticidal combination containing pyridalyl and anabasine, composition contains active components A and active component B, active components A and active component B weight ratio are 1 ︰ 80 ~ 80 ︰ 1, described active components A is selected from pyridalyl, and active component B is selected from the one in thiacloprid, Diacloden, clothianidin, MTI-446.

The described Pesticidal combination containing pyridalyl and anabasine, is characterized in that: the weight ratio of active components A, active component B is 1 ︰ 60 ~ 60 ︰ 1.

The described Pesticidal combination containing pyridalyl and anabasine, is characterized in that: the weight ratio of pyridalyl and thiacloprid is 20:1 ~ 1:20;

The weight ratio of pyridalyl and Diacloden is 20 ︰ 1 ~ 1 ︰ 10;

The weight ratio of pyridalyl and clothianidin is 20 ︰ 1 ~ 1 ︰ 10;

The weight ratio of pyridalyl and MTI-446 is 20 ︰ 1 ~ 1 ︰ 10.

The described Pesticidal combination containing pyridalyl and anabasine, is characterized in that: composition is made wettable powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspending agent-suspending agent.

The purposes of the described Pesticidal combination containing pyridalyl and anabasine for preventing and treating crop pest, described crop comprises cereal crops, fruit tree, fibre crops, vegetables, flowers, legume crop, specifically comprises wheat, paddy rice, corn, tea tree, apple tree, pear tree, mandarin tree, Banana tree, rubber tree, cotton, cucumber, capsicum, wild cabbage, chrysanthemum, rose, soybean etc.; Described insect comprises: aphid, flea beetle, thrips, striped rice borer, yellow rice borer, rice leaf roller, planthopper, diamondback moth, tea lesser leafhopper, cabbage caterpillar, prodenia litura, Americal rice leaf miner, bean-pod borer, melon aphid, Bemisia tabaci, beet armyworm, bollworm, 2 committee noctuids.

Conventionally in composition, the weight percentage of active component is gross weight 1%～90%, is preferably 5%～85%. According to different preparation types, active component content scope is different. Conventionally, liquid preparation contains 1%～70% active material by weight, is preferably 5%～50%; Solid pharmaceutical preparation contains 5%～85% active material by weight, is preferably 10%～80%.

In Pesticidal combination of the present invention, at least contain a kind of surfactant, the dispersion of active component in water while being beneficial to use. Surface-active contents is 10%～40% of total formulation weight amount, and surplus is solid or liquid diluent.

Composition of the present invention can be by user before use through dilution or directly use. Its preparation can be prepared by common processing method known in those skilled in the art, after mixing with liquid flux or solid carrier by active material, then add surfactant as one or more in dispersant, stabilizing agent, wetting agent, emulsifying agent, binding agent, defoamer etc.

Pesticidal combination of the present invention, can be processed on demand acceptable formulation on any agricultural chemicals, wherein the excellent formulation of selecting is: wettable powder, suspending agent, suspension emulsion, water dispersible granules, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspending agent-suspending agent.

When making wettable powder, composition comprises following constituent content: pyridalyl 1% ~ 80%, active component B1% ~ 80%, dispersant 1.5% ~ 10%, wetting agent 1% ~ 10%, filler surplus.

When making suspending agent, composition comprises following constituent content: pyridalyl 1% ~ 50%, active component B1% ~ 50%, dispersant 1% ~ 10%, wetting agent 1% ~ 10%, defoamer 0.01% ~ 1%, thickener 0.05% ~ 2%, antifreeze 0% ~ 8%, deionized water add to 100%.

When making suspension emulsion, composition comprises following constituent content: pyridalyl 1% ~ 50%, active component B1% ~ 50%, solvent 0 ~ 15%, emulsifying agent 2% ~ 12%, dispersant 2% ~ 10%, defoamer 0.01% ~ 2%, thickener 0.05% ~ 2%, antifreeze 0% ~ 8%, stabilizing agent 0% ~ 3%, deionized water add to 100%.

When making aqueous emulsion, composition comprises following constituent content: pyridalyl 1% ~ 50%, active component B1% ~ 50%, solvent 1% ~ 30%, emulsifying agent 1% ~ 20%, co-emulsifier 1% ~ 8%, antifreeze 0% ~ 8%, thickener 0.05% ~ 2%, defoamer 0% ~ 2%, deionized water are supplied surplus.

When making microemulsion, composition comprises following constituent content: pyridalyl 1% ~ 50%, active component B1% ~ 50%, solvent 1% ~ 30%, emulsifying agent 3% ~ 20%, antifreeze 0% ~ 8%, thickener 0.05% ~ 2%, defoamer 0.01% ~ 2%, stabilizing agent 0% ~ 4%, deionized water is supplied surplus.

When making microcapsule suspending agent, composition comprises following constituent content: pyridalyl 1% ~ 50%, active component B1% ~ 50%, macromolecule cyst material 3% ~ 10%, dispersant 2% ~ 10%, organic solvent 0% ~ 10%, emulsifying agent 2% ~ 7%, pH adjusting agent 0.1% ~ 5%, deionized water adds to 100%.

When making microcapsule suspension-suspending agent, composition comprises following constituent content: active components A 1% ~ 40%, active component B1% ~ 60%, macromolecule cyst material 2% ~ 12%, surfactant 3% ~ 15%, organic solvent 1% ~ 5%, emulsifying agent 1% ~ 6%, defoamer 0.2% ~ 5%, thickener 0.05% ~ 1%, pH adjusting agent 1% ~ 5%, water add to 100%.

When making water dispersible granules, composition comprises following constituent content: active one-tenth A1% ~ 80%, active component B1% ~ 80%, dispersant 3% ~ 12%, wetting agent 1% ~ 8%, disintegrant 1% ~ 10%, binding agent 0% ~ 8%, filler surplus.

Suspending agent the key technical indexes of the present invention:

Wettable powder the key technical indexes of the present invention:

Technical indicator	Dispersed	Suspensibility	The moistening time	Fineness (by 45 μ m testing sieves)	Water content
						The all examples of the present invention	≥90%	≥90%	≤ 90 seconds	≥98%	≤2%
Pesticidal products specification requirement	≥80%	≥80%	≤ 120 seconds	≥95%	≤3%

Suspension emulsion the key technical indexes of the present invention:

Microcapsule suspending agent the key technical indexes of the present invention:

Aqueous emulsion the key technical indexes of the present invention:

Microemulsion the key technical indexes of the present invention:

Microcapsule suspension-suspending agent the key technical indexes of the present invention:

Water dispersible granules the key technical indexes of the present invention:

The invention has the advantages that:

(1) pyridalyl and thiacloprid, Diacloden, clothianidin, MTI-446 composite after, there is notable synergistic and lasting effect;

(2) expanded insecticidal spectrum, a lot of insects have been had to greater activity;

(3) reduce the dosage of agricultural chemicals, reduced the residual quantity of agricultural chemicals on crop, alleviated environmental pollution;

(4) to person poultry safety, Environmental compatibility is good, and insect is difficult for developing immunity to drugs.

Detailed description of the invention

Below in conjunction with embodiment, to further instruction of the present invention, the percentage in embodiment is all weight percentage, but the present invention is not limited thereto.

Application Example one

Example 135% pyridalyl Diacloden suspending agent

Pyridalyl 30%, Diacloden 5%, alkylnaphthalene sulfonate 2.5%, lauryl sodium sulfate 4%, C_8~10Aliphatic alcohols 0.3%, Arabic gum 0.1%, ethylene glycol 3%, deionized water adds to 100%, mixes and makes 35% pyridalyl Diacloden suspending agent.

Change Diacloden into embodiment that thiacloprid, clothianidin, MTI-446 equally can be new.

Example 225% pyridalyl Diacloden suspending agent

Pyridalyl 20%, Diacloden 5%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 3%, lauryl sodium sulfate 4%, C_10~20Saturated fat acids 0.2%, xanthans 0.09%, ethylene glycol 4%, deionized water adds to 100%, mixes and makes 25% pyridalyl Diacloden suspending agent.

Example 330% pyridalyl Diacloden suspension emulsion

Pyridalyl 20%, Diacloden 10%, cyclohexanone 2.5%, castor oil polyoxyethylene ether 3.5%, naphthalene sulfonic acid-formaldehyde condensation product 3.9%, Arabic gum 0.05%, ethylene glycol 2.5%, deionized water adds to 100%, mixes and makes 30% pyridalyl Diacloden suspension emulsion.

Example 445% pyridalyl Diacloden suspension emulsion

Pyridalyl 15%, Diacloden 30%, ethyl acetate 6%, styrene polyoxyethylene ether ammonium sulfate salt 4%, aryl phenol polyoxyethylene succinate sulfonate 4.5%, silicone defoaming agent 0.4%, PAA 0.14%, glycerine 1.4%, deionized water adds to 100%, mixes and makes 45% pyridalyl Diacloden suspension emulsion.

Example 581% pyridalyl Diacloden wettable powder

Pyridalyl 80%, Diacloden 1%, octylphenol polyethylene oxyethylene group ether sulfate 5.3%, wetting and penetrating agent F6%, white carbon add to 100%, mix and make 81% pyridalyl Diacloden wettable powder.

Example 660% pyridalyl Diacloden wettable powder

Pyridalyl 30%, Diacloden 30%, two (alkyl) naphthalenesulfonate formaldehyde condensation compound 7%, wetting agent T5%, kaolin add to 100%, mix and make 60% pyridalyl Diacloden wettable powder.

To change Diacloden into embodiment that thiacloprid, clothianidin, MTI-446 equally can be new.

Example 755% pyridalyl Diacloden water dispersible granules

Pyridalyl 50%, Diacloden 5%, the phonetic formaldehyde condensation products sulfate 4% of alkylphenol-polyethenoxy, tea are withered 3%, ammonium sulfate 0.3%, deionized water add to 100%, make 55% pyridalyl Diacloden water dispersible granules.

Example 861% pyridalyl Diacloden water dispersible granules

Pyridalyl 60%, Diacloden 1%, alkyl benzene calcium sulfonate 8%, sldium lauryl sulfate 6%, aluminium chloride 1.3%, diatomite adds to 100%, makes 61% pyridalyl Diacloden water dispersible granules.

Example 930% pyridalyl Diacloden aqueous emulsion

Pyridalyl 6%, Diacloden 24%, 2,4-toluene di-isocyanate(TDI) 7%, ethylene oxide-propylene oxide block copolymer 6%, isobutanol 0.4%, aluminium-magnesium silicate 0.13%, glycerine 0.7%, silicone oil 5%, deionized water adds to 100%, makes 30% pyridalyl Diacloden aqueous emulsion.

Change Diacloden into embodiment that clothianidin, thiacloprid, MTI-446 equally can be new.

Example 1035% pyridalyl Diacloden microemulsion

Pyridalyl 5%, Diacloden 30%, ethyl acetate 3.6%, C_10~20Saturated fat acids 0.5%, Arabic gum 0.06%, NPE 5.3%, propane diols 3%, deionized water adds to 100%, makes 35% pyridalyl Diacloden microemulsion.

By the embodiment that Diacloden changes into, thiacloprid, clothianidin, MTI-446 equally can be new.

Example 1122% pyridalyl Diacloden microcapsule suspending agent

Pyridalyl 2%, Diacloden 20%, polyfunctional group acyl halide polyamines 5.3%, alkyl biphenyl ether disulfonic acid magnesium salts 6.7%, polyethylene glycol 2.7%, AEO 4.3%, NaOH 0.7%, hydrochloric acid 1.4%; deionized water adds to 100%, makes 22% pyridalyl Diacloden microcapsule suspending agent.

Example 1220% pyridalyl Diacloden microcapsule suspending agent-suspending agent

Pyridalyl 15%, Diacloden 5%, polyfunctional group acyl halide dihydroxylic alcohols 8%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 7%, phenethyl phenol polyoxy ethyl polypropylene-base ether 2.8%, solvent naphtha 2.7%, NaOH 1.8%, sorbic acid 1.5%; deionized water adds to 100%, makes 20% pyridalyl Diacloden microcapsule suspending agent-suspending agent.

Example 1340% pyridalyl thiacloprid suspending agent

Pyridalyl 30%, thiacloprid 10%, the phonetic formaldehyde condensation products sulfate 2.3% of alkylphenol-polyethenoxy, Nekal BX 1.6%, C_10~20Saturated fat acids 0.5%, PAA 0.02%, glycerine 1.5%, deionized water adds to 100%, makes 40% pyridalyl thiacloprid suspending agent.

Change thiacloprid into embodiment that Diacloden, clothianidin, MTI-446 equally can be new.

Example 1430% pyridalyl thiacloprid suspending agent

Pyridalyl 20%, thiacloprid 10%, lignosulfonates 6.4%, lauryl sodium sulfate 4.4%, methylcellulose 0.13%, polyethylene glycol 1.7%, C_10~20Saturated fat acids 0.4%, deionized water adds to 100%, makes 30% pyridalyl thiacloprid suspending agent.

Example 1535% pyridalyl thiacloprid suspending agent

Pyridalyl 30%, thiacloprid 5%, solvent N-chain alkyl pyrrolidones 5%, wetting alkylphenol-formaldehyde resin polyoxy ethylether 6.5%, alkyl benzene sulfonate calcium salt 4%, silicone compound 1.2%, aluminium-magnesium silicate 0.12%, deionized water add to 100%, make 35% pyridalyl thiacloprid suspending agent.

Example 1620% pyridalyl thiacloprid suspending agent

Pyridalyl 10%, thiacloprid 10%, dimethyl formamide 4%, benzyl dimethyl phenol polyoxy ethylether 4.5%, alkyl benzene sulfonate calcium salt 2.7%, C_8~10Aliphatic alcohols 1.3%, PAA 0.08%, deionized water add to 100%, make 20% pyridalyl thiacloprid suspending agent.

Example 1770% pyridalyl thiacloprid wettable powder

Pyridalyl 60%, thiacloprid 10%, the phonetic formaldehyde condensation products sulfate 3.5% of alkylphenol-polyethenoxy, neopelex 1.9%, white carbon add to 100%, and mixture carries out air-flow crushing, make 70% pyridalyl thiacloprid wettable powder.

Example 1881% pyridalyl thiacloprid wettable powder

Pyridalyl 1%, thiacloprid 80%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 2.7%, tea are withered 2.9%, attapulgite adds to 100%, and mixture carries out air-flow crushing, makes 81% pyridalyl thiacloprid wettable powder.

Example 1980% pyridalyl thiacloprid water dispersible granules

Pyridalyl 79%, thiacloprid 1%, aryl phenol polyoxyethylene succinate sulfonate 6.5%, silkworm excrement 4.5%, ammonium sulfate 2.4%, bentonite add to 100%, mix and make 80% pyridalyl thiacloprid water dispersible granules.

Example 2061% pyridalyl thiacloprid water dispersible granules

Pyridalyl 1%, thiacloprid 60%, polycarboxylate 4.5%, spaonin powder 4.6%, bentonite 1.6%, kaolin add to 100%, mix and make 61% pyridalyl thiacloprid wettable powder.

Example 2145% pyridalyl thiacloprid aqueous emulsion

Pyridalyl 40%, thiacloprid 5%, carrene 2.7%, triethanolamine salt 6%, isobutanol 1.5%, ethylene glycol 1.8%, hydroxypropyl cellulose 0.14%, silicone 1.3%, deionized water add to 100%, mix and make 45% pyridalyl thiacloprid aqueous emulsion.

Example 2225% pyridalyl thiacloprid microemulsion

Pyridalyl 20%, thiacloprid 5%, cyclohexanone 6.3%, sorbitan fatty acid ester APEO 5.1%, glycerine 2.9%, methylcellulose 0.05%, silicone compound 1.3%, deionized water add to 100%, make 25% pyridalyl thiacloprid microemulsion through mixing.

Change thiacloprid into embodiment that clothianidin, Diacloden, MTI-446 equally can be new.

Example 2330% pyridalyl thiacloprid microcapsule suspending agent

Pyridalyl 10%, thiacloprid 20%, distortion lactoprotein 2.8%, alkyl benzene sulfonate calcium salt 4.6%, sorbitan monostearate 5%, NaOH 1.4%, citric acid 1.5%, deionized water add to 100%, make 30% pyridalyl thiacloprid microcapsule suspending agent through mixing.

Example 2435% pyridalyl thiacloprid microcapsule suspending agent-suspending agent

Pyridalyl 34%, thiacloprid 1%, PIC 4%, propane diols polyoxyethylene polyoxypropylene block polyether 4.5%, ethyl acetate 6%, methacrylate 3.5%, C_10~20Saturated fat acids 0.9%, polyvinyl alcohol 0.05%, NaOH 1.6%, citric acid 2%, deionized water add to 100%, make 35% pyridalyl thiacloprid microcapsule suspending agent-suspending agent through mixing.

Example 2530% pyridalyl clothianidin suspending agent

Pyridalyl 25%, clothianidin 5%, the phonetic formaldehyde condensation products sulfate 4% of alkylphenol-polyethenoxy, sldium lauryl sulfate 3.5%, bentonite 4.5%, C_8~10Aliphatic alcohols 1.1%, Arabic gum 0.09%, ethylene glycol 3.5%, deionized water add to 100%, make 30% pyridalyl clothianidin suspending agent through mixing.

Change clothianidin into embodiment that Diacloden, thiacloprid, MTI-446 equally can be new.

Example 2635% pyridalyl clothianidin suspending agent

Pyridalyl 28%, clothianidin 7%, aliphatic amine polyoxyethylene are phonetic 2.9%, lauryl sodium sulfate 4.9%, silicone compound 3.5%, aluminium-magnesium silicate 0.11%, deionized water add to 100%, make 35% pyridalyl clothianidin suspending agent through mixing.

Example 2750% pyridalyl clothianidin suspension emulsion

Pyridalyl 40%, clothianidin 10%, benzyl dimethyl phenol polyoxy ethylether 6%, 2,4-toluene di-isocyanate(TDI) 4.6%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 3.4%, hydroxypropyl cellulose 0.09%, C_8~10Aliphatic alcohols 1.3%, deionized water add to 100%, make 50% pyridalyl clothianidin suspension emulsion through mixing.

Example 2841% pyridalyl clothianidin suspension emulsion

Pyridalyl 1%, clothianidin 40%, ethyl acetate 6.4%, alkyl benzene calcium sulfonate 6.8%, polyoxyethylene carboxylate 4.5%, xanthans 0.06%, C_10~20Saturated fat acids 1.2%, deionized water add to 100%, make 41% pyridalyl clothianidin suspension emulsion through mixing.

Change clothianidin into embodiment that Diacloden, MTI-446, thiacloprid equally can be new.

Example 2980% pyridalyl clothianidin wettable powder

Pyridalyl 60%, clothianidin 20%, aryl phenol polyoxyethylene succinate sulfonate 2.5%, wetting and penetrating agent F3.5%, kaolin add to 100%, make 80% pyridalyl clothianidin wettable powder through mixing.

Example 3070% pyridalyl clothianidin wettable powder

Pyridalyl 35%, clothianidin 35%, the phonetic formaldehyde condensation products sulfate 5% of alkylphenol-polyethenoxy, spaonin powder 2.4%, attapulgite add to 100%, make 70% pyridalyl clothianidin wettable powder through mixing.

Example 3160% pyridalyl clothianidin water dispersible granules

Pyridalyl 40%, clothianidin 20%, the phonetic formaldehyde condensation products sulfate 2.6% of alkylphenol-polyethenoxy, washing powder 4.6%, urea 3%, bentonite add to 100%, make 60% pyridalyl clothianidin water dispersible granules through mixing.

Change clothianidin into embodiment that MTI-446, Diacloden, thiacloprid equally can be new.

Example 3245% pyridalyl clothianidin water dispersible granules

Pyridalyl 3%, clothianidin 42%, naphthalene sulfonic acid-formaldehyde condensation product sodium salt 4.2%, silkworm excrement 6%, ammonium sulfate 6.5%, precipitated calcium carbonate add to 100%, make 45% pyridalyl clothianidin water dispersible granules through mixing.

Example 3340% pyridalyl clothianidin aqueous emulsion

Pyridalyl 37%, clothianidin 3%, polyethylene glycol 3.6%, AEO 2.8%, butanols 4.6%, polyethylene glycol 4%, C_10~20Saturated fat acids 1%, aluminium-magnesium silicate 0.08%, deionized water adds to 100%, makes 40% pyridalyl clothianidin aqueous emulsion through mixing.

Example 3412% pyridalyl clothianidin microemulsion

Pyridalyl 2%, clothianidin 10%, acetonitrile 8.5%, sorbitan fatty acid ester APEO 5%, polyethylene glycol 1.3%, C_10~20Saturated fat acids 0.8%, Sodium Polyacrylate 0.13%, deionized water adds to 100%, makes 12% pyridalyl clothianidin microemulsion through mixing.

Example 3533% pyridalyl clothianidin microcapsule suspending agent

Pyridalyl 3%, clothianidin 30%, butanols 18%, castor oil polyoxyethylene ether 5%, isobutanol 4%, polyethylene glycol 2%, C_10~20Saturated fat acids 0.5%, hydroxypropyl cellulose 0.06%, deionized water adds to 100%, makes 33% pyridalyl clothianidin microcapsule suspending agent through mixing.

By the embodiment that clothianidin changes into, Diacloden, thiacloprid, MTI-446 equally can be new.

Example 3622% pyridalyl clothianidin microcapsule suspending agent-suspending agent

Pyridalyl 20%, clothianidin 2%, glycerine 10%, alkylaryl polyoxyethylene polyoxypropylene ether 4.6%, ethylene glycol 2.3%, C_8~10Saturated fat acids 0.7%, NPE phosphate 2.8%, NaOH 1.5%, citric acid 2%, deionized water add to 100%, make 22% pyridalyl clothianidin microcapsule suspending agent-suspending agent through mixing.

Change clothianidin into embodiment that thiacloprid, Diacloden, MTI-446 equally can be new.

Example 3740% pyridalyl MTI-446 suspending agent

Pyridalyl 30%, MTI-446 10%, aryl phenol polyoxyethylene succinate sulfonate 9%, silkworm excrement 8%, Arabic gum 0.11%, C_10~20Saturated fat acids 1.2%, deionized water adds to 100%, makes 40% pyridalyl MTI-446 suspending agent through mixing.

Change MTI-446 into embodiment that thiacloprid, Diacloden, clothianidin equally can be new.

Example 3835% pyridalyl MTI-446 suspension emulsion

Pyridalyl 20%, MTI-446 15%, solvent N-chain alkyl pyrrolidones 6.5%, sorbitan monostearate 6.3%, polyoxyethylene carboxylate 2.5%, C_10~20Saturated fat acids 1.5%, methylcellulose 0.13%, glycerine 2%, deionized water adds to 100%, makes 35% pyridalyl MTI-446 suspension emulsion through mixing.

Example 3961% pyridalyl MTI-446 wettable powder

Pyridalyl 1%, MTI-446 60%, aryl phenol polyoxyethylene succinate sulfonate 3.5%, sldium lauryl sulfate 2.5%, starch add to 100%, make 61% pyridalyl MTI-446 wettable powder through mixing.

Change MTI-446 into embodiment that clothianidin, Diacloden, thiacloprid equally can be new.

Example 4070% pyridalyl MTI-446 water dispersible granules

Pyridalyl 50%, MTI-446 20%, naphthalene sulfonic acid-formaldehyde condensation product 2.5%, neopelex 4.5%, ammonium sulfate 4.2%, kaolin add to 100%, make 70% pyridalyl MTI-446 water dispersible granules through mixing.

Example 4130% pyridalyl MTI-446 aqueous emulsion

Pyridalyl 15%, MTI-446 15%, carrene 6%, alkyl biphenyl ether disulfonic acid magnesium salts 7%, isobutanol 4.6%, ethylene glycol 4%, C_8~10Aliphatic alcohols 4.3%, PAA 1%, deionized water add to 100%, make 30% pyridalyl MTI-446 aqueous emulsion through mixing.

The embodiment of the present invention is the method that adopts Toxicity Determination and field test to combine. First pass through Toxicity Determination, co-toxicity coefficient (CTC) after clear and definite two kinds of medicaments are composite by a certain percentage, CTC < 80 is antagonism, 80≤CTC≤120 are summation action, CTC > 120 is synergistic effect, on this basis, then carry out field test.

Test method: respectively the mother liquor of each mixed agent is diluted to five series concentration when test, is placed in respectively beaker for subsequent use. Adopt and first soak the method that connects worm after leaf, after the blade of the same size that does not contact any medicament is soaked to 5s in the liquid configuring, take out, naturally dry, put into insect box, then connect for examination larva, under 25 DEG C of conditions, raise, every processing repeats for 3 times, every to repeat examination borer population used be 50, establishes blank simultaneously, checks dead borer population in 72h, calculate the death rate and corrected mortality, try to achieve virulence regression equation and calculate LC₅₀Value. If the contrast death rate is greater than 10%, be considered as invalid test. Computing formula is as follows:

Borer population alive after borer population-medicine alive before medicine

The death rate (%)=------------× 100

Borer population alive before medicine

The processed group death rate-control group death rate

Corrected mortality (%)=---------------× 100

The 100-control group death rate

Insect corrected mortality is converted into probit value (y), and concentration for the treatment of (μ g/ml) converts logarithm value to (x), draws virulence regression equation with least square method, and calculates thus the value of every kind of medicament. Calculate co-toxicity coefficient CTC according to the abundant equation of Sun Yun. Computing formula following (taking pyridalyl as standard medicament, its toxicity index is 100):

The LC of pyridalyl₅₀

Toxicity index (TI)=------------× 100 of effective active composition B

The LC of effective active composition B₅₀

The LC of pyridalyl₅₀

Toxicity index (ATI)=---------× 100 of M

The LC of M₅₀

TI × the P of theoretical toxicity index (TTI)=pyridalyl of M_PyridalylTI × P of+effective active composition B_{Effective active composition B}

The ATI of M

Co-toxicity coefficient (CTC)=------× 100

The TTI of M

In formula: the mixture that M is different proportionings

P_{Effective active composition B}For effective active composition B shared ratio in composition

P_PyridalylFor pyridalyl shared ratio in composition

A is selected from pyridalyl;

B is selected from following any one compound: the one in Diacloden, thiacloprid, clothianidin, MTI-446.

Application Example two：

For trying insect: planthopper.

Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..

Experimental design: effective lethasl concentration scope of determining pyridalyl, the former medicine of Diacloden and the two different proportioning mixture through pilot study.

Toxicity test result one

The toxicity test of table 1 pyridalyl proportionings different from Diacloden to planthopper

As shown in Table 1, the proportioning of pyridalyl and Thiamethoxam compound control planthopper is in the time of 80 ︰ 1 to 1:80, co-toxicity coefficient is all greater than 120, illustrate that both all show synergistic effect at mixture in 80:1 to 1:80 scope, especially when the proportioning of pyridalyl and Diacloden is during at 20:1 to 1:10, synergistic effect is more obviously outstanding, wherein co-toxicity coefficient maximum in the time that pyridalyl and Diacloden weight ratio are 2 ︰ 1, synergistic effect is the most obvious, find, pyridalyl and Diacloden proportioning are at 20:1 simultaneously, 19:1, 18:1, 17:1, 16:1, 15:1, 14:1, 13:1, 12:1, 11:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, composite to aphid when 1:10, flea beetle, thrips, striped rice borer, yellow rice borer, rice leaf roller, planthopper, diamondback moth, tea lesser leafhopper, cabbage caterpillar, prodenia litura, Americal rice leaf miner, bean-pod borer, melon aphid, Bemisia tabaci, beet armyworm, bollworm also has good synergistic effect, and co-toxicity coefficient is all greater than 120.

Application Example three：

For trying insect: beet armyworm.

Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..

Experimental design: effective lethasl concentration scope of determining pyridalyl, the former medicine of clothianidin and the two different proportioning mixture through pilot study.

Toxicity test result two

The toxicity test of table 2 pyridalyl proportionings different from clothianidin to beet armyworm

As shown in Table 2, the proportioning of the composite control of pyridalyl and clothianidin beet armyworm is in the time of 80 ︰ 1 to 1:80, co-toxicity coefficient is all greater than 120, illustrate that both all show synergistic effect at mixture in 80:1 to 1 ︰ 80 scopes, especially in the time that pyridalyl and clothianidin obtain proportioning at 20:1 to 1:10, synergistic effect is more obviously outstanding, tests through applicant, co-toxicity coefficient maximum in the time that pyridalyl and clothianidin weight ratio are 2 ︰ 1, synergistic effect is the most obvious. find simultaneously, pyridalyl and clothianidin proportioning are at 20:1, 19:1, 18:1, 17:1, 16:1, 15:1, 14:1, 13:1, 12:1, 11:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, composite to aphid when 1:10, flea beetle, thrips, striped rice borer, yellow rice borer, rice leaf roller, planthopper, diamondback moth, tea lesser leafhopper, cabbage caterpillar, prodenia litura, Americal rice leaf miner, bean-pod borer, melon aphid, Bemisia tabaci, bollworm, 2 committee noctuids also have good synergistic effect, co-toxicity coefficient is all greater than 120.

Application Example four：

For trying insect: bollworm.

Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..

Experimental design: effective lethasl concentration scope of determining pyridalyl, the former medicine of thiacloprid and the two different proportioning mixture through pilot study.

Toxicity test result three

The toxicity test of table 3 pyridalyl proportionings different from thiacloprid to bollworm

As shown in Table 3, the proportioning of the composite control of pyridalyl and thiacloprid bollworm is in the time of 80 ︰ 1 to 1:80, co-toxicity coefficient is all greater than 120, illustrate that both all show synergistic effect at mixture in 80:1 to 1 ︰ 80 scopes, especially in the time that pyridalyl and thiacloprid obtain proportioning at 20:1 to 1:20, synergistic effect is more obviously outstanding, tests through applicant, co-toxicity coefficient maximum in the time that pyridalyl and thiacloprid weight ratio are 1 ︰ 1, synergistic effect is the most obvious. find simultaneously, pyridalyl and thiacloprid proportioning are at 20:1, 19:1, 18:1, 17:1, 16:1, 15:1, 14:1, 13:1, 12:1, 11:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 2:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, 1:10, 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18, 1:19, composite to aphid when 1:20, flea beetle, thrips, striped rice borer, yellow rice borer, rice leaf roller, planthopper, diamondback moth, tea lesser leafhopper, cabbage caterpillar, prodenia litura, Americal rice leaf miner, bean-pod borer, melon aphid, Bemisia tabaci, beet armyworm, 2 committee noctuids also have good synergistic effect, co-toxicity coefficient is all greater than 120.

Application Example eight：

For trying insect: tea lesser leafhopper.

Test medicine provides by Shaanxi Welch Crop Protection Co., Ltd..

Experimental design: determine that through pilot study pyridalyl is in effective lethasl concentration scope of the former medicine of MTI-446 and the two different proportioning mixture.

Toxicity test result seven

The toxicity test of table 7 pyridalyl proportionings different from MTI-446 to tea lesser leafhopper

As shown in Table 7, the proportioning of the composite control tea lesser leafhopper of pyridalyl and MTI-446 is in the time of 80 ︰ 1 to 1:80, co-toxicity coefficient is all greater than 120, illustrate that both all show synergistic effect at mixture in 80:1 to 1 ︰ 80 scopes, especially in the time that pyridalyl and MTI-446 obtain proportioning at 20:1 to 1:10, synergistic effect is more obviously outstanding, tests through applicant, co-toxicity coefficient maximum in the time that pyridalyl and MTI-446 weight ratio are 2 ︰ 1, synergistic effect is the most obvious. find simultaneously, pyridalyl and MTI-446 proportioning are at 20:1, 19:1, 18:1, 17:1, 16:1, 15:1, 14:1, 13:1, 12:1, 11:1, 10:1, 9:1, 8:1, 7:1, 6:1, 5:1, 4:1, 3:1, 4:1, 1:1, 1:2, 1:3, 1:4, 1:5, 1:6, 1:7, 1:8, 1:9, composite to aphid when 1:10, flea beetle, thrips, striped rice borer, yellow rice borer, rice leaf roller, planthopper, diamondback moth, cabbage caterpillar, prodenia litura, Americal rice leaf miner, bean-pod borer, melon aphid, Bemisia tabaci, beet armyworm, bollworm, 2 committee noctuids also have good synergistic effect, co-toxicity coefficient is all greater than 120.

Application Example ninePyridalyl and Diacloden and the composite control soybean beet armyworm test of pesticide effectiveness thereof

This EE is in Mang Shan town, city of Henan Yong Cheng one peasant household, and test medicine is researched and developed, provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 10% pyridalyl aqueous emulsion (autogamy), 25% Diacloden water dispersible granules (commercial).

Before medicine, investigation soybean beet armyworm insect pest index, in the dispenser of insect pest early period of origination, investigates insect pest indexes and calculates preventive effect for after dispenser 1 day, 15 days, 30 days. Experimental result is as follows:

Table 8 pyridalyl and Diacloden and the composite control soybean beet armyworm test of pesticide effectiveness thereof

As can be seen from Table 8, after pyridalyl and Thiamethoxam compound, can effectively prevent and treat soybean beet armyworm, prevention effect is all better than the preventive effect of single dose, and the preventive effect time is long. In test scope of medication, target crop is had no adverse effects.

Application Example ten2 committee's noctuid tests of pesticide effectiveness of pyridalyl and Diacloden and composite control of maize thereof

This EE is in Luan Hu town, city of Henan Yong Cheng one peasant household, and test medicine is researched and developed, provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 10% pyridalyl aqueous emulsion (autogamy), 25% Diacloden water dispersible granules (commercial).

Before medicine, 2 committee's noctuid insect pest indexes of investigation corn, in the dispenser of insect pest early period of origination, investigate insect pest indexes and calculate preventive effect for after dispenser 1 day, 15 days, 30 days. Experimental result is as follows:

2 committee's noctuid tests of pesticide effectiveness of table 9 pyridalyl and Diacloden and composite control of maize thereof

As can be seen from Table 9, effective 2 of control of maize committee noctuids after pyridalyl and Thiamethoxam compound, prevention effect is all better than the preventive effect of single dose, and the preventive effect time is long. In test scope of medication, target crop is had no adverse effects.

Application Example 11Pyridalyl and thiacloprid and the composite control rape striped flea-beetle test of pesticide effectiveness thereof

This EE is in acrobatic skill town, Shaanxi, and test medicine is researched and developed, provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 10% pyridalyl aqueous emulsion (autogamy), 480 grams per liter thiacloprid suspending agents (autogamy).

Investigation striped flea-beetle insect pest index before medicine, in the dispenser of insect pest early period of origination, investigates insect pest indexes and calculates preventive effect for after dispenser 1 day, 3 days, 7 days. Experimental result is as follows:

Table 10 pyridalyl and thiacloprid and the test of composite control striped flea-beetle effect thereof

As can be seen from Table 10, after pyridalyl and thiacloprid are composite, can effectively prevent and treat rape striped flea-beetle, prevention effect is all better than the preventive effect of single dose, and the preventive effect time is long. In test scope of medication, target crop is had no adverse effects.

Application Example 12Pyridalyl and thiacloprid and composite control cucumber Control of Aphids thereof

This EE is in Han Jing town, Pucheng county, and test medicine is researched and developed, provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 10% pyridalyl aqueous emulsion (autogamy), 480 grams per liter thiacloprid suspending agents (autogamy).

Before medicine, investigation cucumber aphid insect pest index, in the dispenser of insect pest early period of origination, investigates insect pest indexes and calculates preventive effect for after dispenser 1 day, 15 days, 30 days. Experimental result is as follows:

Table 11 pyridalyl and thiacloprid and composite control cucumber Control of Aphids thereof

As can be seen from Table 11, after pyridalyl and thiacloprid are composite, can effectively prevent and treat cucumber aphid, prevention effect is all better than the preventive effect of single dose, and the preventive effect time is long. In test scope of medication, target crop is had no adverse effects.

Application Example 13The chrysanthemum Bemisia tabaci test of pesticide effectiveness is viewed and admired in pyridalyl and clothianidin and composite control thereof

This EE is in suburb, Xi'an, Shaanxi, and test medicine is researched and developed, provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 10% pyridalyl aqueous emulsion (autogamy), 50% clothianidin water dispersible granules (autogamy).

Before medicine, chrysanthemum Bemisia tabaci insect pest index is viewed and admired in investigation, in the dispenser of insect pest early period of origination, within after dispenser 1 day, 15 days, 30 days, investigates insect pest indexes and calculates preventive effect. Experimental result is as follows:

The chrysanthemum Bemisia tabaci test of pesticide effectiveness is viewed and admired in table 12 pyridalyl and clothianidin and composite control thereof

As can be seen from Table 12, after pyridalyl and clothianidin are composite, can effectively prevent and treat and view and admire chrysanthemum Bemisia tabaci, prevention effect is all better than the preventive effect of single dose, and the preventive effect time is long. In test scope of medication, target crop is had no adverse effects.

Application Example 14Pyridalyl and clothianidin and the composite control paddy rice rice leaf roller test of pesticide effectiveness thereof

This EE is in Hanzhong City suburb, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 10% pyridalyl aqueous emulsion (autogamy), 50% clothianidin water dispersible granules (autogamy).

Before medicine, investigation paddy rice rice leaf roller insect pest index, in the dispenser of insect pest early period of origination, investigates insect pest indexes and calculates preventive effect for after dispenser 1 day, 3 days, 7 days. Experimental result is as follows:

Table 13 pyridalyl and clothianidin and the composite control paddy rice rice leaf roller test of pesticide effectiveness thereof

As can be seen from Table 13, after pyridalyl and clothianidin are composite, can effectively prevent and treat paddy rice rice leaf roller, prevention effect is all better than the preventive effect of single dose, and the preventive effect time is long. In test scope of medication, target crop is had no adverse effects.

Application Example 15Pyridalyl and MTI-446 and the composite control rice-stem borer test of pesticide effectiveness thereof

This EE is in Hanzhong City suburb, Shaanxi Province, and test medicine is researched and developed, provided by Shaanxi Welch Crop Protection Co., Ltd., contrast medicament 10% pyridalyl aqueous emulsion (autogamy), 20% MTI-446 wettable powder (autogamy).

Investigation rice-stem borer insect pest index before medicine, in the dispenser of insect pest early period of origination, investigates insect pest indexes and calculates preventive effect for after dispenser 1 day, 3 days, 7 days. Experimental result is as follows:

Table 14 pyridalyl and MTI-446 and the composite control rice-stem borer test of pesticide effectiveness thereof

As can be seen from Table 14, after pyridalyl and MTI-446 are composite, can effectively prevent and treat rice-stem borer, prevention effect is all better than the preventive effect of single dose, and the preventive effect time is long. In test scope of medication, target crop is had no adverse effects.

Claims

1. containing a Pesticidal combination for pyridalyl and anabasine, it is characterized in that: effective active composition is active components A and active component B, active components A and active component B weight ratio are 1 ︰ 80 ~ 80 ︰ 1; Described active components A is pyridalyl, and active component B is thiacloprid.

2. the Pesticidal combination containing pyridalyl and anabasine according to claim 1, is characterized in that: the weight ratio of active components A, active component B is 1 ︰ 60 ~ 60 ︰ 1.

3. the Pesticidal combination containing pyridalyl and anabasine according to claim 2, is characterized in that: the weight ratio of pyridalyl and thiacloprid is 20:1 ~ 1:20.

4. the Pesticidal combination containing pyridalyl and anabasine according to claim 3, is characterized in that: composition is made wettable powder, water dispersible granules, suspending agent, suspension emulsion, aqueous emulsion, microemulsion, microcapsule suspending agent, microcapsule suspending agent-suspending agent.

5. the purposes for preventing and treating crop pest according to the Pesticidal combination containing pyridalyl and anabasine described in claim 1 to 4 any one.

6. purposes according to claim 5, it is characterized in that, described insect is: aphid, flea beetle, thrips, striped rice borer, yellow rice borer, rice leaf roller, planthopper, diamondback moth, tea lesser leafhopper, cabbage caterpillar, prodenia litura, Americal rice leaf miner, bean-pod borer, Bemisia tabaci, beet armyworm, bollworm, 2 committee noctuids.