CN103301435B - Pharmaceutical composition of treating prostatitis - Google Patents
Pharmaceutical composition of treating prostatitis Download PDFInfo
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- CN103301435B CN103301435B CN201310274902.XA CN201310274902A CN103301435B CN 103301435 B CN103301435 B CN 103301435B CN 201310274902 A CN201310274902 A CN 201310274902A CN 103301435 B CN103301435 B CN 103301435B
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- 239000008194 pharmaceutical composition Substances 0.000 title abstract description 10
- 201000007094 prostatitis Diseases 0.000 title abstract description 8
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- 210000000941 bile Anatomy 0.000 claims abstract description 4
- 239000003814 drug Substances 0.000 claims description 4
- 239000003643 water by type Substances 0.000 claims description 4
- 241000628997 Flos Species 0.000 claims description 3
- 240000008669 Hedera helix Species 0.000 claims description 3
- 235000003143 Panax notoginseng Nutrition 0.000 claims description 3
- 241000180649 Panax notoginseng Species 0.000 claims description 3
- 241000722118 Thlaspi Species 0.000 claims description 3
- MYSWGUAQZAJSOK-UHFFFAOYSA-N ciprofloxacin Chemical compound C12=CC(N3CCNCC3)=C(F)C=C2C(=O)C(C(=O)O)=CN1C1CC1 MYSWGUAQZAJSOK-UHFFFAOYSA-N 0.000 claims description 3
- 239000010135 fructus aurantii immaturus Substances 0.000 claims description 3
- 238000002360 preparation method Methods 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims description 2
- 238000001914 filtration Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 5
- 231100000331 toxic Toxicity 0.000 abstract description 2
- 230000002588 toxic effect Effects 0.000 abstract description 2
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- 241000132012 Atractylodes Species 0.000 abstract 1
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- 235000000722 Celosia argentea Nutrition 0.000 abstract 1
- 244000298479 Cichorium intybus Species 0.000 abstract 1
- 235000007542 Cichorium intybus Nutrition 0.000 abstract 1
- 244000183685 Citrus aurantium Species 0.000 abstract 1
- 235000007716 Citrus aurantium Nutrition 0.000 abstract 1
- 235000011566 Dioscorea spongiosa Nutrition 0.000 abstract 1
- 241000882202 Dioscorea spongiosa Species 0.000 abstract 1
- 244000281702 Dioscorea villosa Species 0.000 abstract 1
- 235000007007 Dolichos lablab Nutrition 0.000 abstract 1
- 241000305491 Gastrodia elata Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
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- 244000112675 Lablab purpureus Species 0.000 abstract 1
- 241000112528 Ligusticum striatum Species 0.000 abstract 1
- 244000280244 Luffa acutangula Species 0.000 abstract 1
- 235000009814 Luffa aegyptiaca Nutrition 0.000 abstract 1
- 244000170916 Paeonia officinalis Species 0.000 abstract 1
- 235000006484 Paeonia officinalis Nutrition 0.000 abstract 1
- 244000131316 Panax pseudoginseng Species 0.000 abstract 1
- 235000003181 Panax pseudoginseng Nutrition 0.000 abstract 1
- 244000248825 Peltandra virginica Species 0.000 abstract 1
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- 241001522129 Pinellia Species 0.000 abstract 1
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- 241001331775 Sauropus spatulifolius Species 0.000 abstract 1
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- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
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- 230000027939 micturition Effects 0.000 description 8
- 210000004908 prostatic fluid Anatomy 0.000 description 7
- 206010052901 Terminal dribbling Diseases 0.000 description 4
- 210000000265 leukocyte Anatomy 0.000 description 4
- 230000014759 maintenance of location Effects 0.000 description 4
- 210000002700 urine Anatomy 0.000 description 4
- 230000001154 acute effect Effects 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 230000003110 anti-inflammatory effect Effects 0.000 description 2
- 238000012258 culturing Methods 0.000 description 2
- 210000002307 prostate Anatomy 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
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- 230000001580 bacterial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
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- 208000013507 chronic prostatitis Diseases 0.000 description 1
- 239000007919 dispersible tablet Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a pharmaceutical composition of treating prostatitis. The pharmaceutical composition is prepared from the following substances by weigh ratio: perfoliote knotweed herb, radix pseudostellariae, fructus broussonetiae, Chinese mahonia stem, manchurian lilac bark, bighead atractylodes rhizome, medulla helwingiae, pseudo-ginseng, witloof, gastrodia elata, thlaspi arvense, dioscorea spongiosa, pinellia ternate, loofah sponge, concha arcae, justicia gendarussa, arisaema cum bile, reddish orange, immature bitter orange, hooker winghead root, tuckahoe, seed of feather cockscomb, liquorice, rhizoma nelumbinis, herba siegesbeckiae, ginger, white lablab bean, semen coicis, semen coicis, chinaroot greenbrier, radix angelicae, sauropus spatulifolius, cortex dictamni, angelica sinensis, ligusticum wallichii, piper cubeba, root of common peony, peach kernel, spina date seed, peucedanum decursivum maxim and kapok. The pharmaceutical composition for treating prostatitis disclosed by the invention has the characteristics of being low in cost, easy to prepare, small in toxic and side effects, significant in curative effect.
Description
Technical field
The present invention relates to drug world, specifically, relate to one and treat prostatitic pharmaceutical composition.
Background technology
Prostatitis is a kind of genitourinary system that male adults is often suffered from.This sick acute stages treated is improper easily changes into chronic phase prostatitis, diverse clinical manifestations, and some patient without obvious acute stage medical history, and only can find when health check-up that there is abnormal change patient local.The antiinflammatory of current clinical treatment prostatitis many employings Western medicine, there is the phenomenon that antiinflammatory is not subsided a swelling, and Western medicine is bad greatly anticaustic.Local injection antibiotic therapy chronic prostatitis curative effect is not remarkable, easily recurs; The wound of operative therapy is large, and patient is more painful.
Summary of the invention
The object of this invention is to provide one and treat prostatitic pharmaceutical composition.
In order to realize object of the present invention, the invention provides one and treat prostatitic pharmaceutical composition, it is made up of the material of following weight proportioning: Herba Polygoni cymosi 17 parts, Radix Pseudostellariae 5 parts, Fructus Broussonetiae 10 parts, Caulis Mahoniae 20 parts, Cortex Syingae Amurensis 16 parts, the Rhizoma Atractylodis Macrocephalae 3 parts, Medulla Stachyuri (Medulla Helwingiae) 10 parts, Radix Notoginseng 5 parts, Herba Cichorii 30 parts, 15 parts, Rhizoma Gastrodiae, Herba Thlaspis 10 parts, Rhizoma Dioscoreae Septemlobae 8 parts, the Rhizoma Pinelliae 5 parts, Retinervus Luffae Fructus 18 parts, Concha Arcae 13 parts, Herba Gendarussae 21 parts, Arisaema Cum Bile 5 parts, Exocarpium Citri Rubrum 7 parts, Fructus Aurantii Immaturus 14 parts, Herba pterocephali 8 parts, 23 parts, Poria, Semen Celosiae 17 parts, 20 parts, Radix Glycyrrhizae, Nodus Nelumbinis Rhizomatis 10 parts, Herba Siegesbeckiae 5 parts, 19 parts, Rhizoma Zingiberis Recens, Semen Lablab Album 14 parts, Semen Coicis 10 parts, Rhizoma Smilacis Chinensis 9 parts, the Radix Angelicae Dahuricae 6 parts, Folium Sauropi 18 parts, Cortex Dictamni 13 parts, Radix Angelicae Sinensis 18 parts, Rhizoma Chuanxiong 21 parts, Fructus Litseae 9 parts, Radix Paeoniae Rubra 8 parts, 12 parts, Semen Persicae, Semen Ziziphi Spinosae 20 parts, RADIX PEUCEDANI 14 parts and Flos Bombacis Malabarici 17 parts.
Preferably, described pharmaceutical composition can be tablet, dispersible tablet, powder or decoction.
The prostatitic pharmaceutical composition for the treatment of of the present invention has the advantages that cost is low, preparation is easy, toxic and side effects is little, curative effect shows.
Detailed description of the invention
Embodiment 1:
Take Herba Polygoni cymosi 17 grams, Radix Pseudostellariae 5 grams, Fructus Broussonetiae 10 grams, Caulis Mahoniae 20 grams, Cortex Syingae Amurensis 16 grams, the Rhizoma Atractylodis Macrocephalae 3 grams, Medulla Stachyuri (Medulla Helwingiae) 10 grams, Radix Notoginseng 5 grams, Herba Cichorii 30 grams, 15 grams, Rhizoma Gastrodiae, Herba Thlaspis 10 grams, Rhizoma Dioscoreae Septemlobae 8 grams, the Rhizoma Pinelliae 5 grams, Retinervus Luffae Fructus 18 grams, Concha Arcae 13 grams, Herba Gendarussae 21 grams, Arisaema Cum Bile 5 grams, Exocarpium Citri Rubrum 7 grams, Fructus Aurantii Immaturus 14 grams, Herba pterocephali 8 grams, 23 grams, Poria, Semen Celosiae 17 grams, 20 grams, Radix Glycyrrhizae, Nodus Nelumbinis Rhizomatis 10 grams, Herba Siegesbeckiae 5 grams, 19 grams, Rhizoma Zingiberis Recens, Semen Lablab Album 14 grams, Semen Coicis 10 grams, Rhizoma Smilacis Chinensis 9 grams, the Radix Angelicae Dahuricae 6 grams, Folium Sauropi 18 grams, Cortex Dictamni 13 grams, Radix Angelicae Sinensis 18 grams, Rhizoma Chuanxiong 21 grams, Fructus Litseae 9 grams, Radix Paeoniae Rubra 8 grams, 12 grams, Semen Persicae, Semen Ziziphi Spinosae 20 grams, RADIX PEUCEDANI 14 grams and Flos Bombacis Malabarici 17 grams, add 5000 ml waters, heat 5 hours at 80 DEG C, filter.In filtering residue, add 3000 ml waters, heat 3 hours at 70 DEG C, filter.Merge twice and filter gained filtrate, be concentrated into 500 milliliters, obtain decoction of the present invention.
Experimental example
50 routine male prostatitis patients, age 28-64 year.The decoction of preparation in embodiment 1 is used to treat.Oral 50 milliliters at every turn, every day respectively takes 1 time sooner or later, continuously treatment 10 days.
Efficacy determination method
Frequent micturition, urgent micturition, dysurea or terminal dribbling and urine retention sense disappear, and rectal touch prostate is normal, prostatic fluid routine examination leukocyte normal (< 10/HP), and the antibacterial culturing feminine gender of prostatic fluid is for curing.Frequent micturition, urgent micturition, dysurea or terminal dribbling and urine retention sense obviously alleviate, and prostatic fluid routine examination leukocyte comparatively before alleviates as taking a turn for the better.Frequent micturition, urgent micturition, dysurea or terminal dribbling and urine retention sense still exist, and the visible a large amount of leukocyte of prostatic fluid routine examination, prostatic fluid positive bacterial culture is invalid.
Through treatment, 50 routine patient's frequent micturitions, urgent micturition, dysurea or terminal dribbling and urine retention sense disappear, and rectal touch prostate is normal, prostatic fluid routine examination leukocyte normal (< 10/HP), the antibacterial culturing of prostatic fluid is negative, all meets the standard of healing.
Claims (1)
1. the application of decoction in the prostatitic medicine of preparation treatment, is characterized in that described decoction is made by following manner: take Herba Polygoni cymosi 17 grams, Radix Pseudostellariae 5 grams, Fructus Broussonetiae 10 grams, Caulis Mahoniae 20 grams, Cortex Syingae Amurensis 16 grams, the Rhizoma Atractylodis Macrocephalae 3 grams, Medulla Stachyuri (Medulla Helwingiae) 10 grams, Radix Notoginseng 5 grams, Herba Cichorii 30 grams, 15 grams, Rhizoma Gastrodiae, Herba Thlaspis 10 grams, Rhizoma Dioscoreae Septemlobae 8 grams, the Rhizoma Pinelliae 5 grams, Retinervus Luffae Fructus 18 grams, Concha Arcae 13 grams, Herba Gendarussae 21 grams, Arisaema Cum Bile 5 grams, Exocarpium Citri Rubrum 7 grams, Fructus Aurantii Immaturus 14 grams, Herba pterocephali 8 grams, 23 grams, Poria, Semen Celosiae 17 grams, 20 grams, Radix Glycyrrhizae, Nodus Nelumbinis Rhizomatis 10 grams, Herba Siegesbeckiae 5 grams, 19 grams, Rhizoma Zingiberis Recens, Semen Lablab Album 14 grams, Semen Coicis 10 grams, Rhizoma Smilacis Chinensis 9 grams, the Radix Angelicae Dahuricae 6 grams, Folium Sauropi 18 grams, Cortex Dictamni 13 grams, Radix Angelicae Sinensis 18 grams, Rhizoma Chuanxiong 21 grams, Fructus Litseae 9 grams, Radix Paeoniae Rubra 8 grams, 12 grams, Semen Persicae, Semen Ziziphi Spinosae 20 grams, RADIX PEUCEDANI 14 grams and Flos Bombacis Malabarici 17 grams, add 5000 ml waters, heats 5 hours at 80 DEG C, filters, in filtering residue, add 3000 ml waters, heat 3 hours at 70 DEG C, filter, merge twice and filter gained filtrate, be concentrated into 500 milliliters, obtain described decoction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310274902.XA CN103301435B (en) | 2013-07-03 | 2013-07-03 | Pharmaceutical composition of treating prostatitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310274902.XA CN103301435B (en) | 2013-07-03 | 2013-07-03 | Pharmaceutical composition of treating prostatitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103301435A CN103301435A (en) | 2013-09-18 |
| CN103301435B true CN103301435B (en) | 2015-06-03 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310274902.XA Expired - Fee Related CN103301435B (en) | 2013-07-03 | 2013-07-03 | Pharmaceutical composition of treating prostatitis |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103599472B (en) * | 2013-10-28 | 2015-08-26 | 李孔琳 | A kind of Chinese medicine composition being used for the treatment of prostatic hyperplasia |
| CN103860894B (en) * | 2014-04-02 | 2016-03-09 | 宋玉明 | A kind of medicine for the treatment of chronic prostatitis |
| CN106265686A (en) * | 2016-07-21 | 2017-01-04 | 赵浩浩 | The pharmaceutical composition of Moracizine Hydrochloride and the application in biological medicine thereof |
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- 2013-07-03 CN CN201310274902.XA patent/CN103301435B/en not_active Expired - Fee Related
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| Publication number | Publication date |
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| CN103301435A (en) | 2013-09-18 |
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| ASS | Succession or assignment of patent right |
Owner name: YIN XIAOYING Free format text: FORMER OWNER: JIA DONGLIN Effective date: 20150430 |
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| C41 | Transfer of patent application or patent right or utility model | ||
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| CB03 | Change of inventor or designer information |
Inventor after: Yin Xiaoying Inventor after: Tan Xiaojie Inventor after: Liu Guixiu Inventor after: Wei Cuimin Inventor before: Jia Donglin |
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| COR | Change of bibliographic data |
Free format text: CORRECT: INVENTOR; FROM: JIA DONGLIN TO: YIN XIAOYING TAN XIAOJIE LIU GUIXIU WEI CUIMIN Free format text: CORRECT: ADDRESS; FROM: 100024 CHAOYANG, BEIJING TO: 266300 QINGDAO, SHANDONG PROVINCE |
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| TA01 | Transfer of patent application right |
Effective date of registration: 20150430 Address after: 266300 pharmacy center, Jiaozhou Central Hospital, 29 Xuzhou Road, Jiaozhou, Shandong, Qingdao Applicant after: Yin Xiaoying Address before: 100024 No. 50 Chaoyang North Road, Beijing, Chaoyang District Applicant before: Jia Donglin |
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| C14 | Grant of patent or utility model | ||
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| CF01 | Termination of patent right due to non-payment of annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20150603 Termination date: 20180703 |