CN103299173B - 制备用于检查的生物标本的自动化系统及方法 - Google Patents

制备用于检查的生物标本的自动化系统及方法 Download PDF

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Publication number
CN103299173B
CN103299173B CN201180064629.7A CN201180064629A CN103299173B CN 103299173 B CN103299173 B CN 103299173B CN 201180064629 A CN201180064629 A CN 201180064629A CN 103299173 B CN103299173 B CN 103299173B
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substrate
stain
specimen
fluid
port
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Chinese (zh)
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CN103299173A (zh
Inventor
D.拉彭
D.扎尼瑟
M.里卡利
B.J.麦基恩
E.D.伊顿
D.普尔
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Constitution Medical Inc
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Constitution Medical Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G01N1/31—Apparatus therefor
    • G01N1/312—Apparatus therefor for samples mounted on planar substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00079—Evaporation covers for slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
    • G01N2035/00099—Characterised by type of test elements
    • G01N2035/00138—Slides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00524—Mixing by agitating sample carrier
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G01N2035/1037—Using surface tension, e.g. pins or wires

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Robotics (AREA)
  • Sampling And Sample Adjustment (AREA)
CN201180064629.7A 2010-11-10 2011-11-09 制备用于检查的生物标本的自动化系统及方法 Active CN103299173B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201710218307.2A CN107478484B (zh) 2010-11-10 2011-11-09 制备用于检查的生物标本的自动化系统及方法

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US46077510P 2010-11-10 2010-11-10
US61/460,775 2010-11-10
US201161510180P 2011-07-21 2011-07-21
US61/510,180 2011-07-21
PCT/US2011/060028 WO2012064873A1 (en) 2010-11-10 2011-11-09 Automated systems and methods for preparing biological specimens for examination

Related Child Applications (1)

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CN201710218307.2A Division CN107478484B (zh) 2010-11-10 2011-11-09 制备用于检查的生物标本的自动化系统及方法

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CN103299173A CN103299173A (zh) 2013-09-11
CN103299173B true CN103299173B (zh) 2017-05-03

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US (4) US8454908B2 (https=)
EP (2) EP3467469B1 (https=)
JP (3) JP5801410B2 (https=)
CN (2) CN103299173B (https=)
AU (2) AU2011326511B2 (https=)
CA (1) CA2817303C (https=)
ES (2) ES2700297T3 (https=)
WO (1) WO2012064873A1 (https=)

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CA2817303A1 (en) 2012-05-18
JP2016020918A (ja) 2016-02-04
ES2700297T3 (es) 2019-02-14
EP2638381A1 (en) 2013-09-18
CN103299173A (zh) 2013-09-11
US10775282B2 (en) 2020-09-15
EP3467469A1 (en) 2019-04-10
JP5801410B2 (ja) 2015-10-28
JP2013545981A (ja) 2013-12-26
ES2959284T3 (es) 2024-02-22
EP2638381B1 (en) 2018-09-05
JP2018059946A (ja) 2018-04-12
AU2015207813A1 (en) 2015-08-20
US20190120736A1 (en) 2019-04-25
US20160209302A1 (en) 2016-07-21
AU2011326511A1 (en) 2013-05-09
JP6268444B2 (ja) 2018-01-31
US9116087B2 (en) 2015-08-25
US10175153B2 (en) 2019-01-08
US20140004561A1 (en) 2014-01-02
CN107478484A (zh) 2017-12-15
US8454908B2 (en) 2013-06-04
WO2012064873A1 (en) 2012-05-18
CN107478484B (zh) 2021-03-30
JP6751382B2 (ja) 2020-09-02
EP3467469B1 (en) 2023-08-16
AU2011326511B2 (en) 2015-04-30
CA2817303C (en) 2019-05-14
AU2015207813B2 (en) 2017-04-27
US20120149050A1 (en) 2012-06-14
HK1244878A1 (zh) 2018-08-17

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