CN103272127B - Preparation for treating epilepsy - Google Patents
Preparation for treating epilepsy Download PDFInfo
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- CN103272127B CN103272127B CN201310236039.9A CN201310236039A CN103272127B CN 103272127 B CN103272127 B CN 103272127B CN 201310236039 A CN201310236039 A CN 201310236039A CN 103272127 B CN103272127 B CN 103272127B
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Abstract
The invention relates to a preparation for treating epilepsy. The preparation comprises substances in parts by weight as follows: stiff silkworms, scarabs, earthworms, centipedes, gastrodia elata, uncaria, peach kernels, flowers carthami, rehmannia glutinosa, radix paeoniae alba, angelica sinensis, ligusticum wallichii, radix achyranthis bidentatae, platycodon grandiflorum, liquorice and rheum officinale. The preparation for treating the epilepsy has the characteristics that the preparation is low in cost, easy to prepare, small in toxic and side effects and remarkable in curative effect.
Description
Technical field
The present invention relates to tcm field, specifically, relate to a kind of medicament for the treatment of epilepsy.
Background technology
Epilepsy is due to brain neuroblastoma unit over-discharge, the central nervous system's who causes unexpected, of short duration or repeatability malfunction, and its pathogenic factor complexity, is the chronic brain disorder being caused by Different types of etiopathogenises.Epilepsy invasion rate increases to some extent in recent years, and the application of carbamazepine is more extensive clinically at present, but owing to there being certain toxic and side effects, and individual adaptability difference is larger.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of epilepsy.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of epilepsy, the material that it comprises following weight proportioning: Bombyx Batryticatus 45-55 part, chafer 90-110 part, Pheretima 45-55 part, Scolopendra 100-150 part, Rhizoma Gastrodiae 140-160 part, Ramulus Uncariae Cum Uncis 45-55 part, Semen Persicae 45-55 part, Flos Carthami 45-55 part, Radix Rehmanniae Preparata 45-55 part, Radix Paeoniae Alba 45-55 part, Radix Angelicae Sinensis 45-55 part, Rhizoma Chuanxiong 45-55 part, Radix Achyranthis Bidentatae 45-55 part, Radix Platycodonis 45-55 part, Radix Glycyrrhizae 45-55 part and Radix Et Rhizoma Rhei 45-55 part.
Preferably, the kit for the treatment of epilepsy of the present invention is containing the material of following weight proportioning: 50 parts of 50 parts of Bombyx Batryticatus, 100 parts of chafers, 50 parts of Pheretimas, 120 parts of Scolopendras, 150 parts, Rhizoma Gastrodiae, 50 parts of Ramulus Uncariae Cum Uncis, 50 parts, Semen Persicae, 50 parts, Flos Carthami, 50 parts, Radix Rehmanniae Preparata, 50 parts of the Radix Paeoniae Albas, 50 parts of Radix Angelicae Sinensis, 50 parts of Rhizoma Chuanxiongs, 50 parts of Radix Achyranthis Bidentataes, 50 parts of Radix Platycodoniss, 50 parts, Radix Glycyrrhizae and Radix Et Rhizoma Rhei.
More preferably, the medicament for the treatment of epilepsy of the present invention also comprises the material of following weight proportioning: 5 parts of 5 parts of Fructus Broussonetiaes, 6 parts of 3 parts of, Herba Thlaspiss of RADIX PEUCEDANI, 5 parts of Rhizoma Smilacis Chinensiss, 7 parts of Herba Cichoriis, Rhizoma Dioscoreae Septemlobae 46 parts of Fen, Herba Siegesbeckiaes, 3 parts of Herba Gendarussaes, 5 parts of Cortex Syingae Amurensiss, 3 parts of Herba pterocephali, 3 parts of Nodus Nelumbinis Rhizomatis, 7 parts of Medulla Stachyuri (Medulla Helwingiae)s, 4 parts of Flos Bombacis Malabaricis, 5 parts of Concha Arcaes, 3 parts of Caulis Mahoniaes, 6 parts of Folium Sauropis, 7 parts of Semen Lablab Albums, 3 parts of Retinervus Luffae Fructuss, 5 parts of Herba Polygoni cymosis, 3 parts of Semen Celosiae and Fructus Litseae.
More preferably, described medicament can be tablet, dispersible tablet, powder or capsule.
In the present invention:
Chinese formal name used at school: chafer circle: regnum animale
Door: Arthropoda Arthropoda subphylum: Mandibulata Mandibulata
Guiding principle: Insecta Isecta subclass: Pterigota Pterygota
Order: coleoptera section: Scarabaeidae
Subfamily: chafer subfamily Scarabaeinae belongs to: chafer belongs to
Kind: chafer
The medicament for the treatment of epilepsy of the present invention has the advantages that cost is low, preparation is easy, toxic and side effects is little, curative effect is showing.
Detailed description of the invention
Embodiment 1:
Take 50 grams of 50 grams of Bombyx Batryticatus, 100 grams of chafers, 50 grams of Pheretimas, 120 grams of Scolopendras, 150 grams, Rhizoma Gastrodiae, 50 grams of Ramulus Uncariae Cum Uncis, 50 grams, Semen Persicae, 50 grams, Flos Carthami, 50 grams, Radix Rehmanniae Preparata, 50 grams of the Radix Paeoniae Albas, 50 grams of Radix Angelicae Sinensis, 50 grams of Rhizoma Chuanxiongs, 50 grams of Radix Achyranthis Bidentataes, 50 grams of Radix Platycodoniss, 50 grams, Radix Glycyrrhizae and Radix Et Rhizoma Rhei, pulverize, cross 80 sieves.Add 200 grams of sucrose, mix homogeneously, then divides and installs in 100 bags, obtains powder of the present invention.
Embodiment 2:
Take 50 grams of Bombyx Batryticatus, 100 grams of chafers, 50 grams of Pheretimas, 120 grams of Scolopendras, 150 grams, Rhizoma Gastrodiae, 50 grams of Ramulus Uncariae Cum Uncis, 50 grams, Semen Persicae, 50 grams, Flos Carthami, 50 grams, Radix Rehmanniae Preparata, 50 grams of the Radix Paeoniae Albas, 50 grams of Radix Angelicae Sinensis, 50 grams of Rhizoma Chuanxiongs, 50 grams of Radix Achyranthis Bidentataes, 50 grams of Radix Platycodoniss, 50 grams, Radix Glycyrrhizae, 50 grams of Radix Et Rhizoma Rhei, 5 grams of Fructus Broussonetiaes, 3 grams of RADIX PEUCEDANI, 6 grams of Herba Thlaspiss, 5 grams of Rhizoma Smilacis Chinensiss, 7 grams of Herba Cichoriis, 4 grams of Rhizoma Dioscoreae Septemlobaes, 6 grams of Herba Siegesbeckiaes, 3 grams of Herba Gendarussaes, 5 grams of Cortex Syingae Amurensiss, 3 grams of Herba pterocephali, 3 grams of Nodus Nelumbinis Rhizomatis, 7 grams of Medulla Stachyuri (Medulla Helwingiae)s, 4 grams of Flos Bombacis Malabaricis, 5 grams of Concha Arcaes, 3 grams of Caulis Mahoniaes, 6 grams of Folium Sauropis, 7 grams of Semen Lablab Albums, 3 grams of Retinervus Luffae Fructuss, 5 grams of Herba Polygoni cymosis, 5 grams of 3 grams of Semen Celosiae and Fructus Litseae, pulverize, cross 80 mesh sieves.Add 350 grams of sucrose, mix homogeneously, then divides and installs in 100 bags, obtains powder of the present invention.
Experimental example
Diagnostic criteria
With reference to international epilepsy alliance in 1989 about epilepsy and the syndromic criteria for classification of epilepsy (Intemational League Against Epilepsy (ILAE) .Commission on Classification and Terminology of the International League Against Epilepsy Proposal for revised classification of epilepsies and epileptic syndromes[J] Epilepsia1989,30 (4): 389-399) and " practical craniocerebral injury " (Liu Mingfeng, practical craniocerebral injury [M] Beijing: People's Medical Officer Press 1992428-431) and " neurosurgery " (Wang Zhongcheng, neurosurgery [M[Wuhan: the 1998365-367 of Hubei science tech publishing house) work out: 1. EEG (electrocardiogram) examination has epilepsy ripple, 2. ictal disturbance of consciousness, faint, twitch, vegetative nerve function is abnormal, 3. without the past encephalitis, cerebral traumas etc. may be led epileptogaenic posteriority illness, and 4. CT or MRI brain scanning show that brain is abnormal.Person is got rid of following situations: before 1. going to a doctor, take other antiepileptics patient; 2. patient person has previously undergone surgery; 3. hepatorenal disease, or other degenerative disease patient; 4. gestation or suckling patient; 5. epilepsy family history patient.
Physical data
Epileptic's 80 examples, male 40 examples, female's 40 examples, minimal ages 11 years old, maximum 61 years old age, average (31 ± 4.6) year, wherein 12 years old following 5 example, 12-50 year 59 examples, 50 years old above 16 example.Duration of seizure after wound: the 1-6 months 11 example, the 7-12 months 18 example, 1-3 25 examples, 3-5 14 examples, 5 years above 12 examples.Be divided into two groups, every group of 40 routine patients, two groups are conveniently compared there was no significant difference (P > 0.05) in sex, age, the course of disease, state of an illness scoring etc., have comparability.
First group of powder prepared by the oral embodiment 1 of patient, every day three times, each oral 3 bags, treating 30 days is 1 course for the treatment of, treats 6 courses for the treatment of.
Second group of powder prepared by the oral embodiment 2 of patient, every day three times, each oral 3 bags, treating 30 days is 1 course for the treatment of, treats 6 courses for the treatment of.
Criterion of therapeutical effect
Invalid: after medication, epilepsy frequency is treated front minimizing less than 50%, and electroencephalogram is unchanged, outbreak symptom is also not improved.Effective: after medication, epilepsy frequency is treated front minimizing 51%-75%, electroencephalogram and outbreak symptom have improvement in various degree.Effective: after medication, epilepsy is substantially controlled, or seizure frequency treats front minimizing and is greater than 75%, and electroencephalogram and outbreak symptom are improved obviously.
Therapeutic outcome
In first group of patient, effective 24 examples, effective 16 examples; In second group of patient, effective 32 examples, effective 8 examples.In observation, do not occur serious adverse reaction, after treatment finishes, two groups of patients' blood, urine, stool routine and hepatic and renal function inspection are showed no extremely.
Claims (1)
1. treat the medicament of epilepsy for one kind, it is characterized in that it is made up of the material of following weight proportioning: 50 parts of Bombyx Batryticatus, 100 parts of chafers, 50 parts of Pheretimas, 120 parts of Scolopendras, 150 parts, Rhizoma Gastrodiae, 50 parts of Ramulus Uncariae Cum Uncis, 50 parts, Semen Persicae, 50 parts, Flos Carthami, 50 parts, Radix Rehmanniae Preparata, 50 parts of the Radix Paeoniae Albas, 50 parts of Radix Angelicae Sinensis, 50 parts of Rhizoma Chuanxiongs, 50 parts of Radix Achyranthis Bidentataes, 50 parts of Radix Platycodoniss, 50 parts, Radix Glycyrrhizae, 50 parts of Radix Et Rhizoma Rhei, 5 parts of Fructus Broussonetiaes, 3 parts of RADIX PEUCEDANI, 6 parts of Herba Thlaspiss, 5 parts of Rhizoma Smilacis Chinensiss, 7 parts of Herba Cichoriis, 4 parts of Rhizoma Dioscoreae Septemlobaes, 6 parts of Herba Siegesbeckiaes, 3 parts of Herba Gendarussaes, 5 parts of Cortex Syingae Amurensiss, 3 parts of Herba pterocephali, 3 parts of Nodus Nelumbinis Rhizomatis, 7 parts of Medulla Stachyuri (Medulla Helwingiae)s, 4 parts of Flos Bombacis Malabaricis, 5 parts of Concha Arcaes, 3 parts of Caulis Mahoniaes, 6 parts of Folium Sauropis, 7 parts of Semen Lablab Albums, 3 parts of Retinervus Luffae Fructuss, 5 parts of Herba Polygoni cymosis, 5 parts of 3 parts of Semen Celosiae and Fructus Litseae.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310236039.9A CN103272127B (en) | 2013-06-17 | 2013-06-17 | Preparation for treating epilepsy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310236039.9A CN103272127B (en) | 2013-06-17 | 2013-06-17 | Preparation for treating epilepsy |
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| Publication Number | Publication Date |
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| CN103272127A CN103272127A (en) | 2013-09-04 |
| CN103272127B true CN103272127B (en) | 2014-08-27 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201310236039.9A Active CN103272127B (en) | 2013-06-17 | 2013-06-17 | Preparation for treating epilepsy |
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Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105497417A (en) * | 2015-12-22 | 2016-04-20 | 刘可 | Traditional Chinese medicine preparation for treating epilepsy as well as preparation method and application of traditional Chinese medicine preparation |
| CN107952055A (en) * | 2017-12-27 | 2018-04-24 | 重庆六脉堂生物科技有限公司 | A kind of Chinese medicine preparation of consciousness regaining and preparation method thereof |
| CN110101804A (en) * | 2019-05-30 | 2019-08-09 | 厦门梓素生物科技有限公司 | A kind of epilepsy drugs combination of the extract containing cannabidiol and preparation method thereof |
| CN114073744A (en) * | 2020-08-07 | 2022-02-22 | 鹤壁市人民医院 | Composition for treating vegetative nervous epilepsy and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101912535A (en) * | 2010-07-17 | 2010-12-15 | 苗丽华 | Medicament for treating pediatric epilepsy |
| CN102335277A (en) * | 2011-10-10 | 2012-02-01 | 成都绿迪科技有限公司 | Oral Chinese medicine for treating epilepsy |
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