CN103301294B - Pharmaceutical composition for treating idiopathic trigeminal neuralgia - Google Patents
Pharmaceutical composition for treating idiopathic trigeminal neuralgia Download PDFInfo
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- CN103301294B CN103301294B CN201310280379.1A CN201310280379A CN103301294B CN 103301294 B CN103301294 B CN 103301294B CN 201310280379 A CN201310280379 A CN 201310280379A CN 103301294 B CN103301294 B CN 103301294B
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Abstract
The invention relates to a pharmaceutical composition for treating idiopathic trigeminal neuralgia. The composition is prepared from the following materials in percentage by weight: Folium Sauropi, Folium Sauropi, rheum officinale, folium isatidis, Polygonum cuspidatum, Peucedanum decursivum Maxim, purslane, Coptis chinensis, saururus chinensis, myrrh, emblic leafflower fruit, Mentha haplocalyx, potentilla discolor, Pterocephalus hookeri, ground beeltle, Rhizoma Drynariae, scorpio, manchurian lilac bark, medulla of stachyurus, Syzygium aromaticum, kapok, zaocys dhumnade, common gendarussa herb, golden cypress, Ligusticum wallichii, rattletop, Chinese azalea flower, radix angelicae, Rhizoma Dioscoreae Septemlobae, cortex dictamni, fructus forsythiae, perfoliote knotweed herb, fenugreek and fenugreek. The pharmaceutical composition for treating idiopathic trigeminal neuralgia provided by the invention has the characteristics of low cost, easiness in preparation, small toxic and side effects and remarkable curative effect.
Description
Technical field
The present invention relates to drug world, specifically, relate to a kind of pharmaceutical composition for the treatment of primary trigeminal neuralgia.
Background technology
Primary trigeminal neuralgia is agnogenic nervi trigeminus areal area of short duration repeated relapsing lightning sample severe pain, and modern medicine it be unclear that its cause of disease and pathogenesis.At present Therapeutic Method is more, though the Therapeutic Method of surgical operation injured nerve has been obtained certain effect, easily leaves over the sensory disturbances such as face fiber crops are swollen, and patient is difficult to accept.
Summary of the invention
The object of this invention is to provide a kind of pharmaceutical composition for the treatment of primary trigeminal neuralgia.
In order to realize object of the present invention, the invention provides a kind of pharmaceutical composition for the treatment of primary trigeminal neuralgia, it is made up of the material of following weight proportioning: 10 parts of Folium Sauropis, 20 parts of Herba Thlaspiss, 45 parts of Radix Et Rhizoma Rhei, 30 parts of Folium Isatidiss, 28 parts of Rhizoma Polygoni Cuspidati, 10 parts of RADIX PEUCEDANI, 30 parts of Herba Portulacaes, 30 parts of Rhizoma Coptidis, 25 parts of Rhizoma Saururi (Herba Saururi)s, 20 parts of Myrrhas, 20 parts of Fructus Phyllanthis, 20 parts of Herba Menthaes, 15 parts of Herba Potentillae Discoloris, 25 parts of Herba pterocephali, 10 parts of Eupolyphaga Seu Steleophagas, 30 parts of Rhizoma Drynariae, 25 parts of Scorpios, 15 parts of Cortex Syingae Amurensiss, 5 parts of Medulla Stachyuri (Medulla Helwingiae)s, 15 parts of Flos Caryophyllis, 10 parts of Flos Bombacis Malabaricis, 15 parts of Zaocyss, 30 parts of Herba Gendarussaes, 25 parts of Cortex Phellodendris, 20 parts of Rhizoma Chuanxiongs, 35 parts of Rhizoma Cimicifugaes, 10 parts of Flos Rhododendri Mollis, 30 parts of the Radixs Angelicae Dahuricae, 20 parts of Rhizoma Et Radix Notopterygiis, 15 parts of Rhizoma Dioscoreae Septemlobaes, 20 parts of Cortex Dictamni, 25 parts of Fructus Forsythiaes, 15 parts of Herba Polygoni cymosis, 10 parts of 20 parts of Semen Trigonellae and Semen Litchis.
Preferably, described pharmaceutical composition can be tablet, dispersible tablet, powder or decoction.
The pharmaceutical composition for the treatment of primary trigeminal neuralgia of the present invention has the advantages that cost is low, preparation is easy, toxic and side effects is little, curative effect is showing.
Detailed description of the invention
Embodiment 1:
Take 10 grams of Folium Sauropis, 20 grams of Herba Thlaspiss, 45 grams of Radix Et Rhizoma Rhei, 30 grams of Folium Isatidiss, 28 grams of Rhizoma Polygoni Cuspidati, 10 grams of RADIX PEUCEDANI, 30 grams of Herba Portulacaes, 30 grams of Rhizoma Coptidis, 25 grams of Rhizoma Saururi (Herba Saururi)s, 20 grams of Myrrhas, 20 grams of Fructus Phyllanthis, 20 grams of Herba Menthaes, 15 grams of Herba Potentillae Discoloris, 25 grams of Herba pterocephali, 10 grams of Eupolyphaga Seu Steleophagas, 30 grams of Rhizoma Drynariae, 25 grams of Scorpios, 15 grams of Cortex Syingae Amurensiss, 5 grams of Medulla Stachyuri (Medulla Helwingiae)s, 15 grams of Flos Caryophyllis, 10 grams of Flos Bombacis Malabaricis, 15 grams of Zaocyss, 30 grams of Herba Gendarussaes, 25 grams of Cortex Phellodendris, 20 grams of Rhizoma Chuanxiongs, 35 grams of Rhizoma Cimicifugaes, 10 grams of Flos Rhododendri Mollis, 30 grams of the Radixs Angelicae Dahuricae, 20 grams of Rhizoma Et Radix Notopterygiis, 15 grams of Rhizoma Dioscoreae Septemlobaes, 20 grams of Cortex Dictamni, 25 grams of Fructus Forsythiaes, 15 grams of Herba Polygoni cymosis, 10 grams of 20 grams of Semen Trigonellae and Semen Litchis, pulverize, cross 100 mesh sieves, add 120 grams, mannitol, mix homogeneously, divide and install in 1000 bags, obtain powder of the present invention.
Experimental example
1.1 physical data
30 routine patients, male 11 examples, female's 19 examples; Age 30-78 year, average (51.0 ± 10.8) year; The course of disease 6 months-12 years, average (1.3 ± 0.4) year; 1 neuralgia person 9 example, 2 pain person's 19 examples, 3 equal pain person's 2 examples; Right side pain person 21 examples, left side pain person 9 examples.
1.2 diagnostic criteria
With reference to international headache (the international headache society of association in 1988, the standard of the classical trigeminal neuralgia of diagnosis (primary trigeminal neuralgia) of IHS) working out is made a definite diagnosis (Alan M.Rapoport, Fred D.Sheftell, the up-to-date clinical headache treating of R.Allan Purely. is learned [M]. Long Jieyi. and Beijing: publishing house of China Concord Medical Science University, 2003; 235-240.).
With in embodiment 1 preparation powder treat.Each oral 1 bag, every day 3 times, treating continuously 30 days is 1 course for the treatment of.
1.3 criterion of therapeutical effect
Cure: pain outbreak disappears, follow up a case by regular visits to and within 3 months, have no multiple; Take a turn for the better: when attack times reduces and (or) shows effect, pain degree alleviates; Invalid: attack times and outbreak pain degree without alleviating (Sun Chuanxing. clinical disease diagnosis is according to curing improvement standard [S] .2 version. Beijing: People's Medical Officer Press, 1998:198-200).
Through treatment, 30 routine patient's pain outbreaks disappear, and follow up a case by regular visits to and within 3 months, have no multiple, therefore meet the criterion of therapeutical effect of healing completely, and in therapeutic process, do not observe obvious untoward reaction.
Claims (1)
1. treat the pharmaceutical composition of primary trigeminal neuralgia for one kind, it is characterized in that it is made up of the material of following weight proportioning: 10 parts of Folium Sauropis, 20 parts of Herba Thlaspiss, 45 parts of Radix Et Rhizoma Rhei, 30 parts of Folium Isatidiss, 28 parts of Rhizoma Polygoni Cuspidati, 10 parts of RADIX PEUCEDANI, 30 parts of Herba Portulacaes, 30 parts of Rhizoma Coptidis, 25 parts of Rhizoma Saururi (Herba Saururi)s, 20 parts of Myrrhas, 20 parts of Fructus Phyllanthis, 20 parts of Herba Menthaes, 15 parts of Herba Potentillae Discoloris, 25 parts of Herba pterocephali, 10 parts of Eupolyphaga Seu Steleophagas, 30 parts of Rhizoma Drynariae, 25 parts of Scorpios, 15 parts of Cortex Syingae Amurensiss, 5 parts of Medulla Stachyuri (Medulla Helwingiae)s, 15 parts of Flos Caryophyllis, 10 parts of Flos Bombacis Malabaricis, 15 parts of Zaocyss, 30 parts of Herba Gendarussaes, 25 parts of Cortex Phellodendris, 20 parts of Rhizoma Chuanxiongs, 35 parts of Rhizoma Cimicifugaes, 10 parts of Flos Rhododendri Mollis, 30 parts of the Radixs Angelicae Dahuricae, 20 parts of Rhizoma Et Radix Notopterygiis, 15 parts of Rhizoma Dioscoreae Septemlobaes, 20 parts of Cortex Dictamni, 25 parts of Fructus Forsythiaes, 15 parts of Herba Polygoni cymosis, 10 parts of 20 parts of Semen Trigonellae and Semen Litchis.
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| CN201310280379.1A CN103301294B (en) | 2013-07-05 | 2013-07-05 | Pharmaceutical composition for treating idiopathic trigeminal neuralgia |
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| CN201310280379.1A CN103301294B (en) | 2013-07-05 | 2013-07-05 | Pharmaceutical composition for treating idiopathic trigeminal neuralgia |
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| CN103301294A CN103301294A (en) | 2013-09-18 |
| CN103301294B true CN103301294B (en) | 2014-07-16 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105853636A (en) * | 2016-05-04 | 2016-08-17 | 陈红 | Pharmaceutical composition for treating pyrophlegm attacking type primary prosopalgia |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3623363A1 (en) | 2016-09-21 | 2020-03-18 | Celanese International Corporation | Acesulfame potassium compositions and processes for producing same |
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| CN1306851A (en) * | 2000-01-28 | 2001-08-08 | 傅红喜 | Chinese medicine preparation for treating toothache |
| CN101269160A (en) * | 2008-04-03 | 2008-09-24 | 徐恒雁 | Chinese medicinal composition for treating trigeminal neuralgia |
| CN103028018A (en) * | 2011-09-29 | 2013-04-10 | 刘清友 | Preparation method of traditional Chinese medicine prescription for treating prosopalgia |
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2013
- 2013-07-05 CN CN201310280379.1A patent/CN103301294B/en not_active Expired - Fee Related
Patent Citations (3)
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|---|---|---|---|---|
| CN1306851A (en) * | 2000-01-28 | 2001-08-08 | 傅红喜 | Chinese medicine preparation for treating toothache |
| CN101269160A (en) * | 2008-04-03 | 2008-09-24 | 徐恒雁 | Chinese medicinal composition for treating trigeminal neuralgia |
| CN103028018A (en) * | 2011-09-29 | 2013-04-10 | 刘清友 | Preparation method of traditional Chinese medicine prescription for treating prosopalgia |
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| 三叉神经痛中医治疗进展;陈风华等;《实用中医药杂志》;20090131;第25卷(第1期);55-57 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105853636A (en) * | 2016-05-04 | 2016-08-17 | 陈红 | Pharmaceutical composition for treating pyrophlegm attacking type primary prosopalgia |
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Owner name: CAI XIAOQING Free format text: FORMER OWNER: WANG HUI Effective date: 20140612 |
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Free format text: CORRECT: INVENTOR; FROM: WANG HUI TO: CAI XIAOQING Free format text: CORRECT: ADDRESS; FROM: 100193 HAIDIAN, BEIJING TO: 272000 JINING, SHANDONG PROVINCE |
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Effective date of registration: 20140612 Address after: Shandong City, Jining province 272000 City Central City Road No. 28, Department of pharmacy Jining Osteology and Traumatology Hospital Applicant after: Cai Xiaoqing Address before: 100193, No. 9, building No. 8, West flourishing road, Haidian District, Beijing Applicant before: Wang Hui |
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