CN103263566A - Traditional Chinese medicine composition for treating bone dilated cardiomyopathy - Google Patents
Traditional Chinese medicine composition for treating bone dilated cardiomyopathy Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine composition for treating dilated cardiomyopathy, which is prepared from the following components: 15-20g of radix astragali, 10-15g of rhizoma atractylodis macrocephalae, 10-15g of evergreen, 10-15g of convallaria, 10-20g of dangshen, 10-15g of monkshood, 12-18g of semen lepidii, 8-12g of mulberry bark, 10-15g of Plantain seed, 8-12g of tuckahoe, 4-8g of muscardine silkworm, 10-15g of fructus aurantii, 8-12g of kudzu root, 8-12g of Fructus Forsythiae, 8-12g of radix rehmanniae, 2-5g of cinnabar and 8-12g of licorice. The traditional Chinese medicine composition for treating dilated cardiomyopathy has the advantages of reasonable compatibility, obvious curative effect and quick effect taking; and the clinical experiment proves that the effective rate is high. The invention has the advantages of simple preparation technique, wide medicine sources, low cost, serious material selection and no dependent medicinal components, and can invigorate qi, nourish the blood, tonify qi, nourish yin, mildly nourish the heart veins, boost the heart-yang, relieve mental stress and restrain the dissipating heart-qi.
Description
Technical field
The present invention relates to contain the medicinal preparation that derives from plant, animal or raw mineral materials, particularly a kind of Chinese medicine composition for the treatment of DCM (dilated cardiomyopathy).
Background technology
Cardiomyopathy is a kind of cause of disease complexity, and basic lesion betides cardiac muscle, causes the heart disease that cardiac muscle can not normal contraction.With cardiac dilatation, paroxysmal nocturnal dyspnea, edema of lower limbs, or cardiopalmus, uncomfortable in chest, angina pectoris etc. are clinical principal character.Cardiomyopathy is divided into two types of primary cardiac myopathy and secondary cardiomyopathys by the cause of disease; Be divided into three types of dilated cardiomyopathy, hypertrophic cardiomyopathy and restrictive cardiomyopathys by pathology, wherein dilated cardiomyopathy comparatively more sees that restrictive cardiomyopathy is domestic rare.The cardiomyopathy onset is slow, and the course of disease is different in size, categories such as " cardiopalmus ", " thoracic obstruction " of the card genus traditional Chinese medical science, " the syndrome of dyspnea ", " edema ".Hypertrophic cardiomyopathy is interventricular septum and ventricle wall plumpness, and ventricular chamber diminishes, and ventricular filling is limited, and the relaxing period compliance drops to the cardiomyopathy of basic characteristics.
Expanding cardiopathia is the abbreviation of dilated cardiomyopathy, and dilated cardiomyopathy (DCM) is modal type in the cardiomyopathy.Primary disease sees all ages and classes, different sexes.But man more than the woman, and with the young and the middle aged for seeing more.The cardiomyopathy symptom: the feature of dilated cardiomyopathy shows as cardiac dilatation mainly based on dilatation of heart, and congestive heart failure and arrhythmia etc. merge relative property Bicuspid valve or tricuspid incompetence sometimes.According to clinical experience for many years, patient's ultrasoundcardiogram is shown with following characteristics: ventricular chamber obviously enlarges, and the OMV amplitude is little.Bicuspid valve is compared relative less with the ventricular chamber of expansion.Interventricular septum and LVPW are changeable thin, the characteristics of interventricular septum and LVPW hypomotility.DCM (dilated cardiomyopathy), as its name suggests, dilated cardiomyopathy must have the expansion of ventricle, and popular saying is exactly cardiac enlargement, big heart, and its clinical course comprises incubation period, early stage and late period.Clinical each phase is unusual with corresponding Pathophysiology, carries out the transition to tangible heart failure (abbreviation heart failure) gradually.There is certain limitation in the western medical treatment DCM (dilated cardiomyopathy), and at first, because cause of disease elaboration is unclear, the treatment of doctor trained in Western medicine at present only limits to symptomatic treatment, cures the symptoms, not the disease.Secondly, the medicine of western medicine and medical practitioners treatment dilated cardiomyopathy such as metoprolol, carvedilol, enalapril etc., only beneficial to the patient who heart failure do not occur in early days, most patients can mitigation symptoms, but to later stage heart failure serious patients with heart failure particularly, because it may reduce cardiac contractile force, worsen cardiac function, can cause that sb.'s illness took a turn for the worse.So in the myocardiac later stage, the therapeutical effect of western medicine and medical practitioners is limited.Later stage can only be adopted the operation that undergos surgery of intervention means, and still, the easily recurrence of operation back is difficult to effect a permanent cure.
The traditional Chinese medical science is for all kinds of cardiopathic treatments especially distinctive feature, and tradition claims that it is " obstruction of qi in the chest and cardialgia ".Result from classical Chinese medicine before the two thousand years " in the emperor through ", " cardiopathia " just had the argumentation of big piece of writing system, think the heart be " the viscus likened to the monarch in the body, here gods go out, the master of blood vessels is most important." definition of proposition " cardiopathia elder generation the heart logical ", and tell different disease types such as " epigastralgia, lung is pained, gallbladder are pained, hepatic precordial pain for pericardial pain with cold limbs, angina pectoris ".This and modern medicine are very approaching to various cardiopathic differentiations.Afterwards, traditional Chinese medical science scholar had had very great development to cardiopathic treatment research on this basis, particularly the cardiopathic cause of disease had been had systematic understanding, pointed out 6 big factors of heart disease morbidity: 1, not enough, the deficiency of qi and blood of talent; 2, seven emotions are crossed the utmost point, the QI and blood consumption is contrary; 3, the turbid interior life of expectorant, blood vessels are obstructed; 4, blood-stasis internal-depression, inaccessible blood vessels; 5, attack in outer Xing, heart arteries and veins is impaired; 6, internal organs are deficient, the mistake of heart arteries and veins is foster; Simultaneously, the successive dynasties physician also according to traditional Chinese medical science thoughts such as " harmony between man and nature ", " dialectical diagnosis and treatment ", " because of people Shi Zhi ", has created colourful Therapeutic Method and experience.
The traditional Chinese medical science does not have myocardiac noun, is equivalent to categories such as cardiopalmus, palpitation with a distress feeling, the obstruction of heart-QI, the syndrome of dyspnea.The traditional Chinese medical science thinks that its pathogenesis is congenital deficiency of spleen-YANG and kidneyYANG, perhaps after the prolonged illness a little less than the deficiency of YANG QI, can not replenishing vital QI with drugs of warm nature heart arteries and veins, and flaccidity of the heart-yang adds that exopathogen, blood stasis, expectorant are turbid, diseases caused by retention of fluid etc. causes a disease for trouble.Chinese traditional treatment this when sick, can belong to and be categories such as Chinese medicine " cardiopalmus ", " palpitation with a distress feeling ", " the syndrome of dyspnea ", " edema with the heart involved ".Its pathogenesis is changed to deficiency in origin and excess in superficiality, simulataneous insufficiency and excessive.Negative and positive of qi and blood void all as seen, but with syndrome of deficiency of both qi and yin for seeing more.Primary disease is the natural endowment deficiency, deficiency of kidney-essence, and essence is activating QI not; Perhaps lose the day after tomorrow and support, excessive overstrain, drinking and eating irregularly, spleen and stomach function are strong, smart evaporation source deficiency; Or experience wind-heat evil toxin, and consume the sad cloudy motive, eventually to lack of preservation of spirit, stagnation of heart-blood, thus cardiopalmus is uncomfortable in chest, shortness of breath and fatigue, oliguria edema.Check visible cardiac dilatation, the ventricle wall attenuation, cardiac ejection fraction reduction etc. is unusual.So when treatment, main benefiting QI and nourishing blood, the QI invigorating YIN nourishing, replenishing vital QI with drugs of warm nature heart arteries and veins, the heart-yang of bestirring oneself, mind tranquilizing and the heart calming, the motive of convergence dissipations must be supported heart body, and the heart is with again often.
Summary of the invention
Technical problem to be solved by this invention is to solve the prior art Chinese medicine and selects less the problem that can't effect a permanent cure with the intervention means, provide a kind of technology simple, medicament sources is extensive, with low cost, can benefiting QI and nourishing blood, the QI invigorating YIN nourishing, replenishing vital QI with drugs of warm nature heart arteries and veins, the heart-yang of bestirring oneself, mind tranquilizing and the heart calming, a kind of Chinese medicine composition for the treatment of DCM (dilated cardiomyopathy) of the motive of convergence dissipation.
For solving the problems of the technologies described above, the invention provides a kind of Chinese medicine composition for the treatment of DCM (dilated cardiomyopathy), wherein, comprise the following component that arranges according to unit of weight: Radix Astragali 15-20g, Rhizoma Atractylodis Macrocephalae 10-15g, Rohdea japonica Roth 10-15g, convallaria 10-15g, Radix Codonopsis 10-20g, Radix Aconiti Lateralis Preparata 10-15g, Semen Lepidii (Semen Descurainiae) 12-18g, Cortex Mori 8-12g, Semen Plantaginis 10-15g, Poria 8-12g, Bombyx Batryticatus 4-8g, Fructus Aurantii 10-15g, Radix Puerariae 8-12g, Fructus Forsythiae 8-12g, Radix Rehmanniae 8-12g, Cinnabaris 2-5g, Radix Glycyrrhizae 8-12g.
Perhaps, comprise the following component that arranges according to unit of weight: Radix Astragali 15-18g, Rhizoma Atractylodis Macrocephalae 10-12g, Rohdea japonica Roth 10-12g, convallaria 10-12g, Radix Codonopsis 10-25g, Radix Aconiti Lateralis Preparata 10-12g, Semen Lepidii (Semen Descurainiae) 12-15g, Cortex Mori 8-10g, Semen Plantaginis 10-12g, Poria 8-10g, Bombyx Batryticatus 4-6g, Fructus Aurantii 10-12g, Radix Puerariae 8-10g, Fructus Forsythiae 8-10g, Radix Rehmanniae 8-10g, Cinnabaris 2-3g, Radix Glycyrrhizae 8-10g.
Perhaps, comprise the following component that arranges according to unit of weight: Radix Astragali 18-20g, Rhizoma Atractylodis Macrocephalae 12-15g, Rohdea japonica Roth 12-15g, convallaria 12-15g, Radix Codonopsis 15-20g, Radix Aconiti Lateralis Preparata 12-15g, Semen Lepidii (Semen Descurainiae) 15-18g, Cortex Mori 10-12g, Semen Plantaginis 12-15g, Poria 10-12g, Bombyx Batryticatus 6-8g, Fructus Aurantii 12-15g, Radix Puerariae 10-12g, Fructus Forsythiae 10-12g, Radix Rehmanniae 10-12g, Cinnabaris 3-5g, Radix Glycyrrhizae 10-12g.
Described Chinese medicine composition is decoction, powder, honey refining pill, hydration pill, tablet, capsule, oral liquid, granule or syrup.
The administering mode of described Chinese medicine composition is oral.
In order better to realize the object of the invention the invention also discloses a kind of preparation method for the treatment of the Chinese medicine composition of DCM (dilated cardiomyopathy), wherein, operate according to following steps:
Each component is put into the little fire of marmite fried 5～10 minutes, respectively it is ground into smalls with pulverizer, sieve; Slot size 80-100 order;
Sieve smalls adopt ultraviolet radiation to carry out disinfection.
Compared with prior art, advantage of the present invention is: compatibility of the present invention is rationally evident in efficacy, instant effect, clinical trial certificate effective percentage height; Preparation technology of the present invention is simple, and medicament sources is extensive, and is with low cost, can benefiting QI and nourishing blood, the QI invigorating YIN nourishing, replenishing vital QI with drugs of warm nature heart arteries and veins, the heart-yang of bestirring oneself, mind tranquilizing and the heart calming, the motive of convergence dissipations, selection is careful, and nothing has dependent ingredient, so patient takes for a long time also and can not produce dependency.Through clinical treatment 82 examples, wherein effective percentage reaches 92.3%, good rate 88.4%.
The specific embodiment
The primary disease traditional Chinese medical science is the natural endowment deficiency, deficiency of kidney-essence, and essence is activating QI not; Perhaps lose the day after tomorrow and support, excessive overstrain, drinking and eating irregularly, spleen and stomach function are strong, smart evaporation source deficiency; Or experience wind-heat evil toxin, and consume the sad cloudy motive, eventually to lack of preservation of spirit, stagnation of heart-blood, thus cardiopalmus is uncomfortable in chest, shortness of breath and fatigue, oliguria edema.Check visible cardiac dilatation, the ventricle wall attenuation, cardiac ejection fraction reduction etc. is unusual.So when treatment, main benefiting QI and nourishing blood, the QI invigorating YIN nourishing, replenishing vital QI with drugs of warm nature heart arteries and veins, the heart-yang of bestirring oneself, mind tranquilizing and the heart calming, the motive of convergence dissipations must be supported heart body, and the heart is with again often.
The present invention adopts following set of dispense recently to realize above-mentioned purpose:
Radix Astragali 15-20g, Rhizoma Atractylodis Macrocephalae 10-15g, Rohdea japonica Roth 10-15g, convallaria 10-15g, Radix Codonopsis 10-20g, Radix Aconiti Lateralis Preparata 10-15g, Semen Lepidii (Semen Descurainiae) 12-18g, Cortex Mori 8-12g, Semen Plantaginis 10-15g, Poria 8-12g, Bombyx Batryticatus 4-8g, Fructus Aurantii 10-15g, Radix Puerariae 8-12g, Fructus Forsythiae 8-12g, Radix Rehmanniae 8-12g, Cinnabaris 2-5g, Radix Glycyrrhizae 8-12g.
Perhaps, comprise the following component that arranges according to unit of weight: Radix Astragali 15-18g, Rhizoma Atractylodis Macrocephalae 10-12g, Rohdea japonica Roth 10-12g, convallaria 10-12g, Radix Codonopsis 10-25g, Radix Aconiti Lateralis Preparata 10-12g, Semen Lepidii (Semen Descurainiae) 12-15g, Cortex Mori 8-10g, Semen Plantaginis 10-12g, Poria 8-10g, Bombyx Batryticatus 4-6g, Fructus Aurantii 10-12g, Radix Puerariae 8-10g, Fructus Forsythiae 8-10g, Radix Rehmanniae 8-10g, Cinnabaris 2-3g, Radix Glycyrrhizae 8-10g.
Perhaps, comprise the following component that arranges according to unit of weight: Radix Astragali 18-20g, Rhizoma Atractylodis Macrocephalae 12-15g, Rohdea japonica Roth 12-15g, convallaria 12-15g, Radix Codonopsis 15-20g, Radix Aconiti Lateralis Preparata 12-15g, Semen Lepidii (Semen Descurainiae) 15-18g, Cortex Mori 10-12g, Semen Plantaginis 12-15g, Poria 10-12g, Bombyx Batryticatus 6-8g, Fructus Aurantii 12-15g, Radix Puerariae 10-12g, Fructus Forsythiae 10-12g, Radix Rehmanniae 10-12g, Cinnabaris 3-5g, Radix Glycyrrhizae 10-12g.
Above-mentioned prescription is for square substantially,
If patient's expectorant stasis of blood adds Ramulus Cinnamomi, each 10g of Rhizoma Polygoni Cuspidati,
If patient has viral myocarditis to make the transition, add Radix Sophorae Flavescentis, each 10g of Rhizoma Coptidis.
If patient with the flatulence edema, can add Fructus Crataegi, each 10g of Pericarpium Citri Reticulatae Viride.
Chinese medicine composition is decoction, powder, honey refining pill, hydration pill, tablet, capsule, oral liquid, granule or syrup.The administering mode of Chinese medicine composition is oral.
During preparation, each component is put into the little fire of marmite fried 5～10 minutes, respectively it is ground into smalls with pulverizer, sieve; Slot size 80-100 order; Sieve smalls adopt ultraviolet radiation to carry out disinfection.
Example 1:
Mr. Lu, 46 years old, man, slight labour be dyspnea and cardiopalmus (atrial fibrillation or ventricular arrhythmia) then.With angina pectoris, cardiopalmus, Mild edema.Tachycardia during rest, heart slightly increases, the apex beat disperse, fourth heart sound strengthens.Be diagnosed as DCM (dilated cardiomyopathy), take following prescription:
Radix Astragali 15g, Rhizoma Atractylodis Macrocephalae 10g, Rohdea japonica Roth 10g, convallaria 10g, Radix Codonopsis 10g, Radix Aconiti Lateralis Preparata 10g, Semen Lepidii (Semen Descurainiae) 12g, Cortex Mori 8g, Semen Plantaginis 10g, Poria 8g, Bombyx Batryticatus 4g, Fructus Aurantii 10g, Radix Puerariae 8g, Fructus Forsythiae 8g, Radix Rehmanniae 8g, Cinnabaris 2g, Radix Glycyrrhizae 8g.
Be decocted in water for oral dose, every pair decocts 3 times, and medicinal liquid is converted together clothes at twice, and one pair of every day, 15 days is a course for the treatment of, take 3 courses for the treatment of after, symptom obviously alleviates, and consolidates afterwards and takes half a year, symptom disappears substantially.Visit after 1 year, do not have recurrence.
Example 2
Mr. Liu, the man, 39 years old, nervous, uncomfortable in chest, feel suffocated, look into electrocardiogram: the chamber of taking place frequently is premature ventricular beat early, and myocardium enzyme increases, arrhythmia, mitral incompetence causes blood reflux, and cardiac auscultation can be heard noise.Color ultrasound examination has cardiac dilatation and cardiac ejection fraction to descend, the normal or attenuation of ventricle wall.Be diagnosed as DCM (dilated cardiomyopathy), take following prescription:
Radix Astragali 20g, Rhizoma Atractylodis Macrocephalae 15g, Rohdea japonica Roth 15g, convallaria 15g, Radix Codonopsis 20g, Radix Aconiti Lateralis Preparata 15g, Semen Lepidii (Semen Descurainiae) 18g, Cortex Mori 12g, Semen Plantaginis 15g, Poria 12g, Bombyx Batryticatus 8g, Fructus Aurantii 15g, Radix Puerariae 12g, Fructus Forsythiae 12g, Radix Rehmanniae 12g, Cinnabaris 5g, Radix Glycyrrhizae 12g.
Be decocted in water for oral dose, every pair decocts 3 times, and medicinal liquid is converted together clothes at twice, and one pair of every day, 15 days is a course for the treatment of, take 3 courses for the treatment of after, symptom obviously alleviates, and consolidates afterwards and takes 4 courses for the treatment of, symptom disappears substantially.Visit after half a year, do not have recurrence.
Example 3
Mrs Wang, 52 years old, heart enlarged left, and apex beat strengthens, with angina pectoris, left bundle branch block and myocardium repolarization abnormality and cause the unusual of ST-T section on the electrocardiogram, exertional dyspnea, nervous, arrhythmia, oppression of heart.Cardiac muscle biopsy has the inflammatory performance, and the Coxsackie B virus NAT is higher than the normal person in the blood.Be diagnosed as DCM (dilated cardiomyopathy), and make the transition from viral myocarditis.
During treatment, add Radix Sophorae Flavescentis, each 10g of Rhizoma Coptidis, all the other components are: Radix Astragali 18g, Rhizoma Atractylodis Macrocephalae 12g, Rohdea japonica Roth 12g, convallaria 12g, Radix Codonopsis 15g, Radix Aconiti Lateralis Preparata 12g, Semen Lepidii (Semen Descurainiae) 15g, Cortex Mori 10g, Semen Plantaginis 12g, Poria 10g, Bombyx Batryticatus 6g, Fructus Aurantii 12g, Radix Puerariae 10g, Fructus Forsythiae 10g, Radix Rehmanniae 10g, Cinnabaris 3g, Radix Glycyrrhizae 10g.
Be decocted in water for oral dose, every pair decocts 3 times, and medicinal liquid is converted together clothes at twice, and one pair of every day, 15 days is a course for the treatment of, take 4 courses for the treatment of after, symptom obviously alleviates, and consolidates afterwards and takes 6 courses for the treatment of, symptom disappears substantially.Visit after half a year, do not have recurrence.
Example 4
Mr. Sun, 55 years old, uncomfortable in chest, chest pain was felt suffocated, breathe hard, cardiac dilatation, apex beat strengthens, and heart circle surpasses midclavicular line, and left side praising property of parasternal is beaten, livid purple when orthopnea and even peace and quiet, develop into heart dyscrasia, skeletonize, lower limb, edema of scrotum the whole latter stage of disease.Be diagnosed as DCM (dilated cardiomyopathy).
In view of edema is arranged, add Fructus Crataegi during treatment, each 10g of Pericarpium Citri Reticulatae Viride, all the other components are Radix Astragali 20g, Rhizoma Atractylodis Macrocephalae 15g, Rohdea japonica Roth 15g, convallaria 15g, Radix Codonopsis 20g, Radix Aconiti Lateralis Preparata 15g, Semen Lepidii (Semen Descurainiae) 18g, Cortex Mori 12g, Semen Plantaginis 15g, Poria 12g, Bombyx Batryticatus 8g, Fructus Aurantii 15g, Radix Puerariae 12g, Fructus Forsythiae 12g, Radix Rehmanniae 12g, Cinnabaris 5g, Radix Glycyrrhizae 12g.
Be decocted in water for oral dose, every pair decocts 3 times, and medicinal liquid is converted and divided clothes together three times, and one pair of every day, 15 days is a course for the treatment of, take 6 courses for the treatment of after, symptom obviously alleviates, consolidation was afterwards taken three months, symptom disappears substantially.Visit after half a year, do not have recurrence.
Example 5
Mr. Zhang, 64 years old, cardiopalmus was susceptible to fright, little sleep disturbed by dreams, shortness of breath and fatigue, moving then cardiopalmus, malaise, stagnation of turbid phlegm in middle-JIAO, shortness of breath and palpitation, cough is panted, moving then aggravation, abundant expectoration is greasy in vain, it is indigestion and loss of appetite to feel sick, and tongue fur is white thick greasy, slippery and rapid pulse, and cardiac auscultation has noise, is diagnosed as DCM (dilated cardiomyopathy).
In view of stagnation of turbid phlegm in middle-JIAO, add Ramulus Cinnamomi during treatment, each 10g of Rhizoma Polygoni Cuspidati, all the other components are Radix Astragali 20g, Rhizoma Atractylodis Macrocephalae 15g, Rohdea japonica Roth 15g, convallaria 15g, Radix Codonopsis 20g, Radix Aconiti Lateralis Preparata 15g, Semen Lepidii (Semen Descurainiae) 18g, Cortex Mori 12g, Semen Plantaginis 15g, Poria 12g, Bombyx Batryticatus 8g, Fructus Aurantii 15g, Radix Puerariae 12g, Fructus Forsythiae 12g, Radix Rehmanniae 12g, Cinnabaris 5g, Radix Glycyrrhizae 12g.
Be decocted in water for oral dose, every pair decocts 3 times, and medicinal liquid is converted and divided clothes together three times, and one pair of every day, 15 days is a course for the treatment of, take 6 courses for the treatment of after, symptom obviously alleviates, consolidation was afterwards taken three months, symptom disappears substantially.Visit after half a year, do not have recurrence.
The present invention is to the protective effect of mice hypoxia-bearing capability: 120 of test mices; male; every group is further divided at random under normal pressure, normal pressure+ISO and three kinds of conditions of low pressure and tests after the administration of animal last, and the result has obvious enhancing mice hypoxia-bearing capability with showing this medicine treatment 8 days.
Zoopery shows, the experiment of blood pressure, heart rate and electrocardiogram positive rate before and after the ischemia is shown that this medicine can obviously resist the myocardial ischemia symptom that pituitrin causes.Change for the serum lactic dehydrogenase isozyme that has pituitrin to cause shows that cardiac muscle is had significant protective effect.
Influence to rat blood serum T-CHOL and platelet aggregation and adhesion function: zoopery shows can significantly reduce serum and liver cholesterol level, can significantly improve hematoblastic gathering and adhesion function.
Influence to the mice stress ability: 64 rat random packet treatments are after 6 days, and except normal group, all the other each groups cause the blood stasis animal model, survey whole blood contrast viscosity behind the drug treatment next day, plasma viscosity, the packed cell volume percentage rate, erythrocyte is built up indexs such as index.The result shows this medicine to the high shear rate of blood stasis rat, and low shear rate, RBC are built up the exponential sum plasma viscosity and compared the effect of having clear improvement.
To rat heart function and hemodynamic influence: can obviously increase CO, the CI of normal rat, low dose of this medicine LVSP that still can raise, with 35 minutes significantly.Other cardiac functions and hemodynamic index there is not obvious influence.
Influence to myocardial function, metabolism and form: this invention is to ischemia rat heart function and hemodynamic influence: experimental results show that, MI (myocardial infarction) group back 35 minutes in infraction, mean arterial pressure in the time of 50 minutes, Lvsp ,-dp/atmax, CO, CI etc. all significantly reduce, and this medicine can make the mean arterial pressure behind the MI, LVSP ,+increase such as dp/dtmax, CO, CI, the most remarkable with small dose group.
Compatibility of the present invention is rationally evident in efficacy, instant effect, clinical trial certificate effective percentage height; Preparation technology of the present invention is simple, and medicament sources is extensive, and is with low cost, can benefiting QI and nourishing blood, the QI invigorating YIN nourishing, replenishing vital QI with drugs of warm nature heart arteries and veins, the heart-yang of bestirring oneself, mind tranquilizing and the heart calming, the motive of convergence dissipations, selection is careful, and nothing has dependent ingredient, so patient takes for a long time also and can not produce dependency.Through clinical treatment 82 examples, wherein effective percentage reaches 92.3%, good rate 88.4%.
Claims (6)
1. a Chinese medicine composition for the treatment of DCM (dilated cardiomyopathy) is characterized in that, comprises the following component that arranges according to unit of weight: Radix Astragali 15-20g, Rhizoma Atractylodis Macrocephalae 10-15g, Rohdea japonica Roth 10-15g, convallaria 10-15g, Radix Codonopsis 10-20g, Radix Aconiti Lateralis Preparata 10-15g, Semen Lepidii (Semen Descurainiae) 12-18g, Cortex Mori 8-12g, Semen Plantaginis 10-15g, Poria 8-12g, Bombyx Batryticatus 4-8g, Fructus Aurantii 10-15g, Radix Puerariae 8-12g, Fructus Forsythiae 8-12g, Radix Rehmanniae 8-12g, Cinnabaris 2-5g, Radix Glycyrrhizae 8-12g.
2. according to the Chinese medicine composition of the described treatment DCM (dilated cardiomyopathy) of claim 1, it is characterized in that, comprise the following component that arranges according to unit of weight: Radix Astragali 15-18g, Rhizoma Atractylodis Macrocephalae 10-12g, Rohdea japonica Roth 10-12g, convallaria 10-12g, Radix Codonopsis 10-25g, Radix Aconiti Lateralis Preparata 10-12g, Semen Lepidii (Semen Descurainiae) 12-15g, Cortex Mori 8-10g, Semen Plantaginis 10-12g, Poria 8-10g, Bombyx Batryticatus 4-6g, Fructus Aurantii 10-12g, Radix Puerariae 8-10g, Fructus Forsythiae 8-10g, Radix Rehmanniae 8-10g, Cinnabaris 2-3g, Radix Glycyrrhizae 8-10g.
3. according to the Chinese medicine composition of the described treatment DCM (dilated cardiomyopathy) of claim 1, it is characterized in that, comprise the following component that arranges according to unit of weight: Radix Astragali 18-20g, Rhizoma Atractylodis Macrocephalae 12-15g, Rohdea japonica Roth 12-15g, convallaria 12-15g, Radix Codonopsis 15-20g, Radix Aconiti Lateralis Preparata 12-15g, Semen Lepidii (Semen Descurainiae) 15-18g, Cortex Mori 10-12g, Semen Plantaginis 12-15g, Poria 10-12g, Bombyx Batryticatus 6-8g, Fructus Aurantii 12-15g, Radix Puerariae 10-12g, Fructus Forsythiae 10-12g, Radix Rehmanniae 10-12g, Cinnabaris 3-5g, Radix Glycyrrhizae 10-12g.
4. according to the Chinese medicine composition of the arbitrary described treatment DCM (dilated cardiomyopathy) of claim 1-3, it is characterized in that described Chinese medicine composition is decoction, powder, honey refining pill, hydration pill, tablet, capsule, oral liquid, granule or syrup.
5. according to the Chinese medicine composition of the arbitrary described treatment DCM (dilated cardiomyopathy) of claim 1-3, it is characterized in that the administering mode of described Chinese medicine composition is oral.
One kind arbitrary as claim 1-3 as described in the preparation method of Chinese medicine composition for the treatment of DCM (dilated cardiomyopathy), it is characterized in that, operate according to following steps:
Each component is put into the little fire of marmite fried 5～10 minutes, respectively it is ground into smalls with pulverizer, sieve; Slot size 80-100 order;
Sieve smalls adopt ultraviolet radiation to carry out disinfection.
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| CN104984037A (en) * | 2015-07-27 | 2015-10-21 | 青岛云天生物技术有限公司 | Traditional Chinese medicine preparation for treatment of dilated cardiomyopathy and preparing method thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102038844A (en) * | 2010-12-31 | 2011-05-04 | 纪承寅 | Chinese medicine composition for treating dilated cardiomyopathy |
| CN103263594A (en) * | 2013-04-29 | 2013-08-28 | 翁炳焕 | Traditional Chinese medicine composition for treating dilated cardiomyopathy |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102038844A (en) * | 2010-12-31 | 2011-05-04 | 纪承寅 | Chinese medicine composition for treating dilated cardiomyopathy |
| CN103263594A (en) * | 2013-04-29 | 2013-08-28 | 翁炳焕 | Traditional Chinese medicine composition for treating dilated cardiomyopathy |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104984037A (en) * | 2015-07-27 | 2015-10-21 | 青岛云天生物技术有限公司 | Traditional Chinese medicine preparation for treatment of dilated cardiomyopathy and preparing method thereof |
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