CN103249741B - 肽 - Google Patents

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Publication number
CN103249741B
CN103249741B CN201180059041.2A CN201180059041A CN103249741B CN 103249741 B CN103249741 B CN 103249741B CN 201180059041 A CN201180059041 A CN 201180059041A CN 103249741 B CN103249741 B CN 103249741B
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CN
China
Prior art keywords
peptide
fty
fsy
food
ace
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201180059041.2A
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English (en)
Chinese (zh)
Other versions
CN103249741A (zh
Inventor
J·拉沃
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Marealis AS
Original Assignee
Marealis AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Publication of CN103249741A publication Critical patent/CN103249741A/zh
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Publication of CN103249741B publication Critical patent/CN103249741B/zh
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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • A23K20/147Polymeric derivatives, e.g. peptides or proteins
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/18Peptides; Protein hydrolysates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/612Crustaceans, e.g. crabs, lobsters, shrimps, krill or crayfish; Barnacles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0812Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Polymers & Plastics (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Insects & Arthropods (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201180059041.2A 2010-10-26 2011-07-13 Active CN103249741B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB1018125.3A GB201018125D0 (en) 2010-10-26 2010-10-26 Peptide
GB1018125.3 2010-10-26
PCT/GB2011/051314 WO2012056205A1 (en) 2010-10-26 2011-07-13 Peptide

Publications (2)

Publication Number Publication Date
CN103249741A CN103249741A (zh) 2013-08-14
CN103249741B true CN103249741B (zh) 2015-12-02

Family

ID=43365585

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201180059041.2A Active CN103249741B (zh) 2010-10-26 2011-07-13

Country Status (11)

Country Link
US (2) US9044511B2 (https=)
EP (1) EP2632937B8 (https=)
JP (1) JP5879356B2 (https=)
CN (1) CN103249741B (https=)
AU (1) AU2011322287B2 (https=)
BR (1) BR112013009679B1 (https=)
CA (1) CA2856153C (https=)
DK (1) DK2632937T3 (https=)
GB (1) GB201018125D0 (https=)
RU (1) RU2572623C2 (https=)
WO (1) WO2012056205A1 (https=)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107337711A (zh) * 2017-07-26 2017-11-10 盐城卫生职业技术学院 一种抗高血压活性肽Citn‑Pro‑Hyp及应用和药物组合物
CN107325153A (zh) * 2017-07-26 2017-11-07 盐城卫生职业技术学院 一种抗高血压活性肽Citn‑Hyp‑Pro及应用和药物组合物
JPWO2021059840A1 (ja) * 2019-09-27 2021-10-07 太陽化学株式会社 アンジオテンシン変換酵素阻害剤
TWI890506B (zh) * 2024-06-27 2025-07-11 開曼群島商味丹國際(控股)有限公司 具有抑制ace活性之胜肽及其組合物

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1780851A (zh) * 2003-05-01 2006-05-31 科内尔研究基金会 将分子递送到细胞的方法和载体复合物
CN101217971A (zh) * 2005-07-05 2008-07-09 比奥滕普特公司 肿瘤的治疗

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4455303A (en) * 1983-05-24 1984-06-19 The General Hospital Corporation Renin inhibitors
US5545719A (en) 1990-05-01 1996-08-13 Neuromedica, Inc. Nerve growth peptides
RU2084458C1 (ru) * 1993-05-27 1997-07-20 Институт высокомолекулярных соединений РАН Декапептид, обладающий противоопухолевой активностью
WO2005007090A2 (en) * 2003-07-03 2005-01-27 President And Fellows Of Harvard College Inhibitors of the map kinase pathway
AU2003253301A1 (en) 2003-07-31 2004-07-14 Franco Felici Peptides mimicking vibrio cholerae o139 capsular polysaccharide and their use to elicit protective immune response
AT502292B1 (de) 2005-05-11 2010-04-15 Avir Green Hills Biotechnology Melanomdiagnose
WO2007117444A2 (en) * 2006-03-31 2007-10-18 Yinghe Hu Protein detection by aptamers
HUP0600814A3 (en) * 2006-10-27 2009-08-28 Biostatin Gyogyszerkutato Fejl Peptides for activation of angiogenesis, pharmaceutical compounds containing same and use of these compounds
CN101092450A (zh) * 2007-01-10 2007-12-26 中国人民解放军第三军医大学第一附属医院 与人mhc-ⅰ类分子结合的肝素酶多肽表位
EP3103467A1 (en) * 2008-02-07 2016-12-14 Cornell University Methods for preventing or treating insulin resistance
FR2943346B1 (fr) 2009-03-19 2011-05-06 Univ Paris Curie Peptides modulant l'activite de l'igf-1 et leurs applications
GB201008462D0 (en) 2010-05-20 2010-07-07 Marealis As Process

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1780851A (zh) * 2003-05-01 2006-05-31 科内尔研究基金会 将分子递送到细胞的方法和载体复合物
CN101217971A (zh) * 2005-07-05 2008-07-09 比奥滕普特公司 肿瘤的治疗

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
"Angiotensin I–converting enzyme inhibitory peptides derived from food proteins and their physiological and pharmacological effects;Guan-Hong Li et al.;《Nutrition Research》;20040731;第24卷(第7期);第470段图1,第471页第1段,第473页表1,第474页第2段,第475页最后一段,第480页第1段 *
Latent Production of Angiotensin I-Converting Enzyme Inhibitors from Buckwheat Protein;CHUN-HUI LI et al.;《J. Peptide Sci.》;20020601;第8卷(第6期);第271页左栏第2段,第272页表2, *

Also Published As

Publication number Publication date
CN103249741A (zh) 2013-08-14
US20130281358A1 (en) 2013-10-24
JP5879356B2 (ja) 2016-03-08
BR112013009679A2 (pt) 2016-07-12
WO2012056205A1 (en) 2012-05-03
RU2572623C2 (ru) 2016-01-20
JP2014500245A (ja) 2014-01-09
EP2632937A1 (en) 2013-09-04
CA2856153C (en) 2019-04-16
RU2013124991A (ru) 2014-12-10
AU2011322287A1 (en) 2013-05-02
EP2632937B1 (en) 2016-03-16
GB201018125D0 (en) 2010-12-08
AU2011322287B2 (en) 2015-06-25
CA2856153A1 (en) 2012-05-03
EP2632937B8 (en) 2016-06-22
US9044511B2 (en) 2015-06-02
BR112013009679B1 (pt) 2020-12-01
DK2632937T3 (en) 2016-05-30
US20150315236A1 (en) 2015-11-05

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