CN103239754A - Composite medical dressing using calcium alginate fibers - Google Patents
Composite medical dressing using calcium alginate fibers Download PDFInfo
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- CN103239754A CN103239754A CN2013101797223A CN201310179722A CN103239754A CN 103239754 A CN103239754 A CN 103239754A CN 2013101797223 A CN2013101797223 A CN 2013101797223A CN 201310179722 A CN201310179722 A CN 201310179722A CN 103239754 A CN103239754 A CN 103239754A
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Abstract
The invention relates to a composite medical dressing using calcium alginate fibers. The composite medical dressing comprises a surface layer, an intermediate layer and a wound contact layer, and is characterized in that the surface layer is made of polyester fiber non-woven fabrics; the intermediate layer and the wound contact layer are made of calcium alginate fiber and polyvinyl alcohol fiber mixing needle-punched non-woven fabrics; the content of the calcium alginate fibers in the intermediate layer is 40%-70%, the content of polyvinyl alcohol fibers in the intermediate layer is 30%-60%, and the gram weight of the intermediate layer is 30-80 g/m<2>; and the content of the calcium alginate fibers in the wound contact layer is 80%-90%, the content of the polyvinyl alcohol fibers in the wound contact layer is 1%-20%, and the gram weight of the wound contact layer is 30-50 g/m<2>. According to the composite medical dressing, the dosage of the calcium alginate fibers can be decreased on the premise of guaranteeing healing effect, thus the production cost is reduced; and the composite medical dressing has the remarkable advantages that a processing technique is simple and chemical adhesives are avoided.
Description
Technical field
The invention belongs to medical dressing, relate to a kind of based composite dressing for medical use of using calcium alginate fibre specifically.
Background technology
Chronic and complicated wound care is the ultimate challenge that global medical field faces, diabetic foot ulcer, venous congestion ulcer, pressure ulcer etc. are typical chronic, complicated wounds, have a strong impact on particularly old people healthy of patient, yet existing medical dressing product but can not satisfy the treatment demand of chronic and complicated wound.
It is moistening relatively and environment sealing is conducive to the healing of wound that modern medical theory proof offers one of wound, people according to this theoretical invention the dressing of a series of new bio intermiscibility high-tech.Calcium alginate fibre has biocompatibility and degradability preferably, ion exchange can also take place and form one deck hydrogel in wound surface in the calcium ion when contacting with wound in the calcium alginate fibre and the sodium ion in the transudate, this hydrogel can absorb moisture and keep the environment of a relative moistening of wound and then play the effect that promotes Wound healing, and calcium alginate fibre can also directly act on the wound macrophage and promote wound healing, so calcium alginate fibre at home and abroad is widely used as the medical dressing material.The seaweed fiber medical dressing deposite device has high moisture absorption, moisture retention, because the formation of hydrogel also has hemostasis, blood coagulation and bacteriostasis, and removes easily, can not cause the secondary wound of wound.
But the alginate fibre price is comparatively expensive, and per kilogram is wanted 300-400 unit, and poor flexibility, brute force are lower, and the price of costliness and physical property defective have all limited it and further popularized application in medical care.
In the prior art, use calcium alginate fibre and see as the technical scheme of medical dressing is quite a few, such as:
The application for a patent for invention of publication number CN1180562 ' manufacture method of Application containing calcium alginate and calcium alginate fibre non-woven fabrics ', its Application containing calcium alginate is the one side that is bonded in non-woven fabrics at the one side employing adhesive of the netted calcium alginate non-woven fabrics of acupuncture, the another side of non-woven fabrics scribbles antitack agent, protective paper is positioned on the another side of the netted shape calcium alginate of acupuncture non-woven fabrics, and is bonding and peelable with the adhesive that is positioned on the non-woven fabrics around it.This functional layer composition of applying ointment or plaster is single, and adopts adhesive to be adhered to non-woven fabrics, and not only production and use cost are higher, and adhesive also influences its breathability.
The application for a patent for invention of publication number CN102580137A ' medicinal functional biological dressing sheet and preparation method thereof ', it is that the calcium alginate fibre of 68.5%-92% and chitin fiber that content is 8%-32.5% are mixed and made into that its medicinal functional biological dressing sheet adopts weight percentage, though strengthened performances such as the antibiotic property of alginate fibre dressing and brute force, the dressing cost further improves.
The application for a patent for invention of publication number CN102600016A ' seaweed fiber medical dressing ', be divided into top layer polyester/non-woven viscose fabric layer and bottom alginate fibre nonwoven layer, and between top layer and bottom, pressed from both sides one deck plastic layer and layer of active carbon layer, and bond together with adhesive.This dressing has waterproof and odor absorption ability preferably, but the manufacturing procedure more complicated, and comfortableness is relatively poor.
The application for a patent for invention of publication number CN202136483U ' medical application ' comprises substrate layer, non-drying glue layer and dressing layer, and dressing layer contains adsorptive pads, built-in hydrogel and it is wrapped up with alginate fibre or chitin fiber in the adsorptive pads.This apply ointment or plaster have good water absorption, the characteristics of adhesion wound, but also have the manufacturing procedure complicated problems, and the use of non-drying glue layer chemistry adhesive has certain influence to the breathability of dressing.
In a word, the calcium alginate fibre medical dressing product of technique scheme and other similar, ubiquity cost and dressing performance can not be taken into account or the defective of processing technique complexity; The technical scheme that has also exists use may have the practical problem of the chemicals of harm to human body.
Summary of the invention
The objective of the invention is to disclose a kind of based composite dressing for medical use of using calcium alginate fibre for overcoming the existing above-mentioned technical problem that contains the medical dressing existence of calcium alginate fibre, this based composite dressing for medical use has demonstrated fully hemostasis, blood coagulation, antibacterial, the effect that promotes wound healing, and improved alginate fibre dressing brute force, reduced production and use cost, and the course of processing is simple, environmental protection.
The present invention takes following technical scheme for achieving the above object: the based composite dressing for medical use of using calcium alginate fibre, comprise surface layer, intermediate layer and wound contact layer, feature is, described surface layer is non-woven fabric of polyester fiber, intermediate layer and wound contact layer are calcium alginate fibre and vinal mixing needle fabric, described intermediate layer calcium alginate fibre content is that 40-70%, vinal content are 30-60%, and the intermediate layer grammes per square metre is 30-80g/m
2, described wound contact layer calcium alginate fibre content is that 80-99%, vinal content are 1%-20%, wound contact layer grammes per square metre is 30-50g/m
2
The present invention can also take following technical measures:
Preferred intermediate layer calcium alginate fibre content is 40%, vinal content is 60%.
Preferred wound contact layer calcium alginate fibre content is 80%, vinal content is 20%.
Described based composite dressing for medical use grammes per square metre is 100-180g/m
2
The non-woven fabric of polyester fiber grammes per square metre of described surface layer is 40-50g/m
2
Described calcium alginate fibre fineness is 3.3dtex, and length is 40mm.
Described vinal is water-soluble fibre, and solution temperature is 90 degree in the water, and length is 33-41mm.
Be the ultrasound wave bonding connection between described surface layer, intermediate layer and the wound contact layer.
Beneficial effect of the present invention is with advantage: the calcium alginate fibre content of the intermediate layer of this based composite dressing for medical use and wound contact layer adopts the gradient laminate structures and gives their different functions, wound contact layer calcium alginate fibre ratio is higher and embody it and absorb rapidly wound fluid and form the effect of curing the wound that hydrogel is covered in wound, and a high proportion of calcium alginate fibre also has softness, use comfortable effect, intermediate layer calcium alginate fibre ratio reduces, the vinal ratio improves, polyvinyl alcohol powerful support the preferably makes the intermediate layer comparatively fluffy, the moisture absorption of this based composite dressing for medical use and venting capability have been improved, the hydrogel that forms after the alginate fibre moisture absorption of intermediate layer can prevent from hardening after the imbibition of this based composite dressing for medical use, has to slow down the effect of changing this based composite dressing for medical use frequency.The vinal that this based composite dressing for medical use adopts has good bioaffinity, biological degradability and environment friendly, hygroscopicity is better in synthetic fibers, close with the Cotton Gossypii performance, and shielding action arranged, the adding of vinal has also improved the brute force of dressing, and greatly reduces the cost of dressing; The use of chemicals such as adhesive has been avoided in the use of ultrasound wave adhering technique, makes the whole production course of processing become an environmental protection technology, has not only reduced pollution but also avoided the damage of chemicals to human body.The present invention can reduce the consumption of calcium alginate fibre and reduce production costs under the prerequisite of effect that guarantees to cure the wound, it is simple and avoid using the outstanding advantage of chemicals bonding agent to have processing technique.
Description of drawings
Accompanying drawing 1 is embodiment of the invention structural representation.
Labelling among the figure: 1 surface layer, 2 intermediate layers, 3 wound contact layers.
The specific embodiment
Further specify the present invention below in conjunction with embodiment and accompanying drawing thereof.
Embodiment 1
As shown in Figure 1, the based composite dressing for medical use of this application calcium alginate fibre comprises surface layer 1, intermediate layer 2 and wound contact layer 3, and described surface layer 1 is to gain the name with this layer position under the use state.Described medical dressing can use packing material commonly used.
The surface layer of embodiment 1 is non-woven fabric of polyester fiber, and grammes per square metre is 40g/m
2, intermediate layer 2 and wound contact layer 3 are calcium alginate fibre and vinal mixing needle fabric, and wherein, the calcium alginate fibre content in intermediate layer is 40%, and vinal content is 60%, and the intermediate layer grammes per square metre is 30g/m
2, the calcium alginate fibre content of wound contact layer is 99%, and vinal content is 1%, and wound contact layer grammes per square metre is 30g/m
2
The based composite dressing for medical use grammes per square metre of embodiment 1 is 100g/m
2Selected calcium alginate fibre fineness is 3.3dtex, and length is 40mm; Selected vinal is water-soluble fibre, and solution temperature is 90 degree in the water, and length is 33-41mm.
As shown in Figure 1, the based composite dressing for medical use of the application calcium alginate fibre of embodiment 2 comprises surface layer 1, intermediate layer 2 and wound contact layer 3.Described medical dressing can use packing material commonly used.
The surface layer of embodiment 2 is non-woven fabric of polyester fiber, and grammes per square metre is 45g/m
2, intermediate layer 2 and wound contact layer 3 are calcium alginate fibre and vinal mixing needle fabric, and wherein, the calcium alginate fibre content in intermediate layer is 55%, and vinal content is 45%, and the intermediate layer grammes per square metre is 50g/m
2, the calcium alginate fibre content of wound contact layer is 90%, and vinal content is 10%, and wound contact layer grammes per square metre is 40g/m
2
The based composite dressing for medical use grammes per square metre of embodiment 2 is 135g/m
2Selected calcium alginate fibre fineness is 3.3dtex, and length is 40mm; Vinal is water-soluble fibre, and solution temperature is 90 degree in the water, and length is 33-41mm.
As shown in Figure 1, the based composite dressing for medical use of the application calcium alginate fibre of embodiment 3 comprises surface layer 1, intermediate layer 2 and wound contact layer 3.Described medical dressing can use packing material commonly used.
The surface layer of embodiment 3 is non-woven fabric of polyester fiber, and grammes per square metre is 50g/m
2, intermediate layer 2 and wound contact layer 3 are calcium alginate fibre and vinal mixing needle fabric, and wherein, the calcium alginate fibre content in intermediate layer is 70%, and vinal content is 30%, and the intermediate layer grammes per square metre is 80g/m
2, the calcium alginate fibre content of wound contact layer is 80%, and vinal content is 20%, and wound contact layer grammes per square metre is 50g/m
2
The based composite dressing for medical use grammes per square metre of embodiment 3 is 180g/m
2Selected calcium alginate fibre fineness is 3.3dtex, and length is 40mm; Vinal is water-soluble fibre, and solution temperature is 90 degree in the water, and length is 33-41mm.
More than the surface layer non-woven fabric of polyester fiber of each embodiment be the commercially available prod.
More than surface layer 1, intermediate layer 2 and the wound contact layer 3 of each embodiment cut according to width and the length of required dressing, each layer order stack after cutting is added together, and realizes the bonding connection of interlayer ultrasound wave with the ultrasound wave bonder.The parameter setting of ultrasound bonder is: pressure roller rotating speed 2.5r/s, output 3.2w, pressure roller pressure 15MPa.
More than the intermediate layer processing process of each embodiment be: calcium alginate fibre, vinal are weighed → are mixed → shredding → combing → acupuncture.
Wherein, described shredding is carried out twice; The parameter of carding machine is during described combing: feeding speed is 0.51r/min, and the licker-in rotating speed is 520.83r/min, and the cylinder rotating speed is 500r/min, and doffer's rotating speed is 8.33r/min, and going out net spee is 4.4m/min; Described needing machine acupuncture parameter is: 2000 pieces/m of bestock, rotating speed are 200r/min.
More than the wound contact layer processing process of each embodiment be: calcium alginate fibre, vinal are weighed → are mixed → shredding → combing → acupuncture → hot rolling.
Wherein, described shredding is carried out twice; The parameter of carding machine is during described combing: feeding speed is 0.51r/min, and the licker-in rotating speed is 520.83r/min, and the cylinder rotating speed is 500r/min, and doffer's rotating speed is 8.33r/min, and going out net spee is 4.4m/min; Described needing machine acupuncture parameter is: 2000 pieces/m of bestock, rotating speed are 200r/min; Described hot-rolled temperature is 190 ℃, and hot rolling is carried out twice.
The specific embodiments more of the present invention that more than provide only are used for specifying technical scheme of the present invention, do not limit the scope of the application's claim protection.
Liquid hygroscopicity test at this based composite dressing for medical use intermediate layer:
According to the processing technique of intermediate layer " calcium alginate fibre, vinal are weighed → mixed → shredding → combing → acupuncture ", produce grammes per square metre respectively and be 60g/m
2, calcium alginate fibre and vinal mixed proportion be respectively three groups of non-weaving cloths of 40/60,55/45,70/30, carries out the test of liquid hygroscopicity according to China's pharmaceuticals industry standard " YY/T0471.1 contact Wound dressing experimental technique first: liquid-absorbent ".
Test result display fibers mixed proportion is that 40/60 the average imbibition quality of non-weaving cloth is 9.9289g/100cm
2, the fiber mixing ratio is that 55/45 the average imbibition quality of non-weaving cloth is 10.2031g/100cm
2, the fiber mixing ratio is that 70/30 the average imbibition quality of non-weaving cloth is 9.0825g/cm
2The fiber mixing ratio is that 40/60 the average imbibition quality of non-weaving cloth and fiber mixing ratio are that 55/45 non-weaving cloth is close and to be better than the fiber mixing ratio be 70/30 non-weaving cloth as can be seen, and visible fiber mixing ratio is that its calcium alginate fibre component content of non-weaving cloth of 40/60 is minimum and the imbibition quality approaches the highest.
More than the non-weaving cloth in the test is equal to intermediate layer of the present invention, so intermediate layer of the present invention optimum fiber mixed proportion is 40/60.
Test at this based composite dressing for medical use wound contact layer gelling characteristic:
According to the processing technique " calcium alginate fibre, vinal are weighed → mixed → shredding → combing → acupuncture → hot rolling " of wound contact layer, produce grammes per square metre respectively and be 40g/m
2, calcium alginate fibre and vinal mixed proportion be respectively three groups of non-weaving cloths of 80/20,90/10 and 99/1, according to the gelling characteristic part of detecting in China's pharmaceuticals industry standard " YY/T0471.1 contact Wound dressing experimental technique first: liquid-absorbent " three groups of non-weaving cloths carried out the gelling characteristic test.
Test result shows that the fiber mixing ratio of 0.2g is that the gel quality affects that 80/20 non-weaving cloth produces is 1.4870g, 0.2g the fiber mixing ratio be that the gel quality affects that 90/10 non-weaving cloth produces is 1.6419g, the fiber mixing ratio of 0.2g is that the gel quality affects that 99/1 non-weaving cloth produces is 1.5802g.The fiber mixing ratio is that the gel content that produces of 80/20 alginate fibre/polyvinyl alcohol nonwovens and fiber mixing ratio are that 99/1 alginate fibre non-weaving cloth is more or less the same as can be seen, but cardability and brute force improve.More than the non-weaving cloth in the test is equal to wound contact layer of the present invention, and therefore wound contact layer optimum fiber mixed proportion of the present invention is 80/20.
Below be to adopt above-mentioned optimum fiber mixed proportion respectively and grammes per square metre different this based composite dressing for medical use sample in intermediate layer carries out result's (seeing the following form) of liquid hygroscopicity test respectively at intermediate layer and wound contact layer:
Test is carried out according to China's pharmaceuticals industry standard " YY/T0471.1 contact Wound dressing experimental technique first: liquid-absorbent ".
Its non-woven fabric of polyester fiber surface layer grammes per square metre of each sample of testing is 50g/m
2, the intermediate layer the ratio of calcium alginate fibre/vinal be 40/60, the ratio of the calcium alginate fibre/vinal of wound contact layer is 80/20.
Each sample of testing is with the three kinds of grammes per square metre groupings in intermediate layer, and 5 every group, dimensions is identical.
Subordinate list illustrates that this based composite dressing for medical use has very strong fluid absorbent, and illustrates that the intermediate layer has outstanding effect to fluid absorbent, and the intermediate layer grammes per square metre can be selected design according to number and the order of severity of wound fluid.
Claims (8)
1. use the based composite dressing for medical use of calcium alginate fibre, comprise surface layer, intermediate layer and wound contact layer, it is characterized in that: described surface layer is non-woven fabric of polyester fiber, intermediate layer and wound contact layer are calcium alginate fibre and vinal mixing needle fabric, described intermediate layer calcium alginate fibre content is that 40-70%, vinal content are 30-60%, and the intermediate layer grammes per square metre is 30-80g/m
2, described wound contact layer calcium alginate fibre content is that 80-99%, vinal content are 1-20%, wound contact layer grammes per square metre is 30-50g/m
2
2. based composite dressing for medical use according to claim 1 is characterized in that: preferred intermediate layer calcium alginate fibre content is 40%, vinal content is 60%.
3. based composite dressing for medical use according to claim 1 is characterized in that: preferred wound contact layer calcium alginate fibre content is 80%, vinal content is 20%.
4. based composite dressing for medical use according to claim 1, it is characterized in that: described based composite dressing for medical use grammes per square metre is 100-180g/m
2
5. based composite dressing for medical use according to claim 1, it is characterized in that: the non-woven fabric of polyester fiber grammes per square metre of described surface layer is 40-50g/m
2
6. based composite dressing for medical use according to claim 1, it is characterized in that: described calcium alginate fibre fineness is 3.3dtex, length is 40mm.
7. based composite dressing for medical use according to claim 1, it is characterized in that: described vinal is water-soluble fibre, and solution temperature is 90 degree in the water, and length is 33-41mm.
8. based composite dressing for medical use according to claim 1 is characterized in that: be the ultrasound wave bonding connection between described surface layer, intermediate layer and the wound contact layer.
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| CN201310179722.3A CN103239754B (en) | 2013-05-15 | 2013-05-15 | Composite medical dressing using calcium alginate fibers |
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| CN201310179722.3A CN103239754B (en) | 2013-05-15 | 2013-05-15 | Composite medical dressing using calcium alginate fibers |
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| CN103239754B CN103239754B (en) | 2015-03-18 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105193547A (en) * | 2015-08-24 | 2015-12-30 | 泰州市榕兴医疗用品股份有限公司 | Medical dressing special for treating diabetes |
| CN112679628A (en) * | 2020-12-24 | 2021-04-20 | 舟山达康科技有限公司 | Medical dressing based on alginate fibers and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100150989A1 (en) * | 2008-12-16 | 2010-06-17 | Douglas Robert Hoffman | Substrates providing multiple releases of active agents |
| EP2228078A1 (en) * | 2009-03-09 | 2010-09-15 | Pietrasanta Pharma S.p.A. | Chitosan and polyurethane foam based medication, production process thereof and use thereof in the wound management |
| CN102600018A (en) * | 2012-03-31 | 2012-07-25 | 华南理工大学 | Medical dressing with cooling function and wound healing prompting function and preparation method of medical dressing |
-
2013
- 2013-05-15 CN CN201310179722.3A patent/CN103239754B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100150989A1 (en) * | 2008-12-16 | 2010-06-17 | Douglas Robert Hoffman | Substrates providing multiple releases of active agents |
| EP2228078A1 (en) * | 2009-03-09 | 2010-09-15 | Pietrasanta Pharma S.p.A. | Chitosan and polyurethane foam based medication, production process thereof and use thereof in the wound management |
| CN102600018A (en) * | 2012-03-31 | 2012-07-25 | 华南理工大学 | Medical dressing with cooling function and wound healing prompting function and preparation method of medical dressing |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105193547A (en) * | 2015-08-24 | 2015-12-30 | 泰州市榕兴医疗用品股份有限公司 | Medical dressing special for treating diabetes |
| CN112679628A (en) * | 2020-12-24 | 2021-04-20 | 舟山达康科技有限公司 | Medical dressing based on alginate fibers and preparation method thereof |
| CN112679628B (en) * | 2020-12-24 | 2021-10-26 | 张家口健垣精准医学有限公司 | Medical dressing based on alginate fibers and preparation method thereof |
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