CN103239754B - Composite medical dressing using calcium alginate fibers - Google Patents
Composite medical dressing using calcium alginate fibers Download PDFInfo
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- CN103239754B CN103239754B CN201310179722.3A CN201310179722A CN103239754B CN 103239754 B CN103239754 B CN 103239754B CN 201310179722 A CN201310179722 A CN 201310179722A CN 103239754 B CN103239754 B CN 103239754B
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Abstract
The invention relates to a composite medical dressing using calcium alginate fibers. The composite medical dressing comprises a surface layer, an intermediate layer and a wound contact layer, and is characterized in that the surface layer is made of polyester fiber non-woven fabrics; the intermediate layer and the wound contact layer are made of calcium alginate fiber and polyvinyl alcohol fiber mixing needle-punched non-woven fabrics; the content of the calcium alginate fibers in the intermediate layer is 40%-70%, the content of polyvinyl alcohol fibers in the intermediate layer is 30%-60%, and the gram weight of the intermediate layer is 30-80 g/m<2>; and the content of the calcium alginate fibers in the wound contact layer is 80%-90%, the content of the polyvinyl alcohol fibers in the wound contact layer is 1%-20%, and the gram weight of the wound contact layer is 30-50 g/m<2>. According to the composite medical dressing, the dosage of the calcium alginate fibers can be decreased on the premise of guaranteeing healing effect, thus the production cost is reduced; and the composite medical dressing has the remarkable advantages that a processing technique is simple and chemical adhesives are avoided.
Description
Technical field
The invention belongs to medical dressing, relate to a kind of based composite dressing for medical use applying calcium alginate fibre specifically.
Background technology
Chronic and complicated wound care is the ultimate challenge of global medical field face, diabetic foot ulcer, venous congestion ulcer, pressure ulcer etc. are typical chronic, complicated wounds, have a strong impact on the healthy of patient particularly old people, but existing medical dressing product but can not meet the Treatment need of chronic and complicated wound.
Modern medical theory proves to be supplied to the relatively moistening and closed environmental benefits of wound one in the healing of wound, people's a series of new bio intermiscibility high-tech dressing according to this theoretical invention.Calcium alginate fibre has good biocompatibility and degradability, ion exchange can also be there is with the calcium ion in calcium alginate fibre during Wound contact and the sodium ion in transudate and form one deck hydrogel in wound surface, this hydrogel can absorb moisture and maintains the environment of a wound relative moistening and then play the effect promoting Wound healing, and calcium alginate fibre can also directly act on wound macrophage promotion wound healing, therefore calcium alginate fibre is at home and abroad widely used as medical dressing material.Seaweed fiber medical dressing deposite device has high moisture absorption, moisture retention, because the formation of hydrogel also has hemostasis, blood coagulation and bacteriostasis, and easily removes, can not cause the secondary insult of wound.
But alginate fibre price costly, per kilogram wants 300-400 unit, and poor flexibility, brute force are lower, and expensive price and physical property defect all limit it and further popularize application in medical care.
In prior art, application calcium alginate fibre is shown in as the technical scheme of medical dressing is quite a few, such as:
The application for a patent for invention ' manufacture method of Application containing calcium alginate and calcium alginate fibre non-woven fabrics ' of publication number CN1180562, its Application containing calcium alginate adopts adhesive to be bonded in the one side of non-woven fabrics in the one side of the netted calcium alginate non-woven fabrics of acupuncture, the another side of non-woven fabrics scribbles antitack agent, protective paper is positioned on the another side of acupuncture net-shaped calcium alginate non-woven fabrics, and its surrounding is bonding with the adhesive be positioned on non-woven fabrics and peelable.This functional layer composition of applying ointment or plaster is single, and adopts adhesive to be adhered to non-woven fabrics, not only produce and use cost higher, adhesive also affects its breathability.
The application for a patent for invention ' medical functional biological dressing and preparation method thereof ' of publication number CN102580137A, its medical functional biological dressing adopts weight percentage to be the calcium alginate fibre of 68.5%-92% and content to be the chitin fiber of 8%-32.5% to be mixed, although enhance the antibiotic property of alginate fibre dressing and the performance such as powerful, dressing cost improves further.
The application for a patent for invention ' seaweed fiber medical dressing ' of publication number CN102600016A, be divided into top layer polyester/non-woven viscose fabric layer and bottom alginate fibre nonwoven layer, and between top layer and bottom, pressed from both sides one deck plastic layer and layer of active carbon layer, and bond together with adhesive.This dressing has good waterproof and odor absorption ability, but manufacturing procedure more complicated, and comfortableness is poor.
The application for a patent for invention ' medical application ' of publication number CN202136483U, comprise substrate layer, non-drying glue layer and dressing layer, dressing layer contains adsorptive pads, and built-in hydrogel in adsorptive pads is also wrapped up with alginate fibre or chitin fiber.This is applied ointment or plaster and has the feature of good water absorption, adhesion wound, but also there is the problem of manufacturing procedure complexity, and the breathability of use to dressing of non-drying glue layer chemistry adhesive has a certain impact.
In a word, the calcium alginate fibre medical dressing product of technique scheme and other similar, ubiquity cost and dressing performance can not be taken into account or the defect of processing technique complexity; Also there is the practical problem using the chemicals that may there is harm to human body in some technical schemes.
Summary of the invention
The object of the invention is for overcoming above-mentioned technical problem that the existing medical dressing containing calcium alginate fibre exists and disclosing a kind of based composite dressing for medical use applying calcium alginate fibre, this based composite dressing for medical use fully demonstrated hemostasis, blood coagulation, antibacterial, promote effect of wound healing, and improve alginate fibre dressing brute force, reduce production and use cost, and the course of processing is simple, environmental protection.
The present invention takes following technical scheme for achieving the above object: the based composite dressing for medical use of application calcium alginate fibre, comprise surface layer, intermediate layer and wound-contacting layer, feature is, described surface layer is non-woven fabric of polyester fiber, intermediate layer and wound-contacting layer are calcium alginate fibre and vinal mixing needle fabric, described intermediate layer calcium alginate fibre content is 40-70%, vinal content is 30-60%, and intermediate layer grammes per square metre is 30-80g/m
2, described wound-contacting layer calcium alginate fibre content is 80-99%, vinal content is 1%-20%, and wound-contacting layer grammes per square metre is 30-50g/m
2.
The present invention can also take following technical measures:
Preferred intermediate layer calcium alginate fibre content is 40%, vinal content is 60%.
Preferred wound-contacting layer calcium alginate fibre content is 80%, vinal content is 20%.
Described based composite dressing for medical use grammes per square metre is 100-180g/m
2.
The non-woven fabric of polyester fiber grammes per square metre of described surface layer is 40-50g/m
2.
Described calcium alginate fibre fineness is 3.3dtex, and length is 40mm.
Described vinal is water-soluble fibre, and in water, solution temperature is 90 degree, and length is 33-41mm.
Described surface layer, between intermediate layer and wound-contacting layer be ultrasonic bonds connect.
Beneficial effect of the present invention and advantage are: the intermediate layer of this based composite dressing for medical use and the calcium alginate fibre content of wound-contacting layer adopt gradient laminate structures and gives their different functions, wound-contacting layer calcium alginate fibre ratio is higher and embody its rapid absorbing wound exudate and form the effect of curing the wound that hydrogel is covered in wound, and a high proportion of calcium alginate fibre also has softness, use comfortable effect, intermediate layer calcium alginate fibre ratio reduces, vinal ratio improves, polyvinyl alcohol preferably powerful support makes intermediate layer comparatively fluffy, improve the moisture absorption of this based composite dressing for medical use and venting capability, the hydrogel formed after the alginate fibre moisture absorption of intermediate layer hardens after can prevent the imbibition of this based composite dressing for medical use, there is the effect that can slow down and change this based composite dressing for medical use frequency.The vinal that this based composite dressing for medical use adopts has good bioaffinity, biological degradability and environment friendly, hygroscopicity is better in synthetic fibers, with Cotton Gossypii similar nature, and have shielding action, vinal add the brute force also improving dressing, and greatly reduce the cost of dressing; The use of sonic bonding techniques avoids the use of the chemicals such as adhesive, makes whole process of manufacture become an environmental protection technique, has both decreased to pollute to turn avoid the damage of chemicals to human body.The present invention can reduce the consumption of calcium alginate fibre and reduces production cost under the prerequisite of effect that ensures to cure the wound, and has processing technique simple and avoid using the outstanding advantages of chemicals bonding agent.
Accompanying drawing explanation
Accompanying drawing 1 is embodiment of the present invention structural representation.
Labelling in figure: 1 surface layer, 2 intermediate layers, 3 wound-contacting layer.
Detailed description of the invention
The present invention is further illustrated below in conjunction with embodiment and accompanying drawing thereof.
Embodiment 1
As shown in Figure 1, the based composite dressing for medical use of this application calcium alginate fibre, comprises surface layer 1, intermediate layer 2 and wound-contacting layer 3, and described surface layer 1 is gained the name with this layer of position under using state.Described medical dressing can use conventional packing material.
The surface layer of embodiment 1 is non-woven fabric of polyester fiber, and grammes per square metre is 40g/m
2, intermediate layer 2 and wound-contacting layer 3 are calcium alginate fibre and vinal mixing needle fabric, and wherein, the calcium alginate fibre content in intermediate layer is 40%, and vinal content is 60%, and intermediate layer grammes per square metre is 30g/m
2, the calcium alginate fibre content of wound-contacting layer is 99%, and vinal content is 1%, and wound-contacting layer grammes per square metre is 30g/m
2.
The based composite dressing for medical use grammes per square metre of embodiment 1 is 100g/m
2; Selected calcium alginate fibre fineness is 3.3dtex, and length is 40mm; Selected vinal is water-soluble fibre, and in water, solution temperature is 90 degree, and length is 33-41mm.
Embodiment 2
As shown in Figure 1, the based composite dressing for medical use of the application calcium alginate fibre of embodiment 2, comprises surface layer 1, intermediate layer 2 and wound-contacting layer 3.Described medical dressing can use conventional packing material.
The surface layer of embodiment 2 is non-woven fabric of polyester fiber, and grammes per square metre is 45g/m
2, intermediate layer 2 and wound-contacting layer 3 are calcium alginate fibre and vinal mixing needle fabric, and wherein, the calcium alginate fibre content in intermediate layer is 55%, and vinal content is 45%, and intermediate layer grammes per square metre is 50g/m
2, the calcium alginate fibre content of wound-contacting layer is 90%, and vinal content is 10%, and wound-contacting layer grammes per square metre is 40g/m
2.
The based composite dressing for medical use grammes per square metre of embodiment 2 is 135g/m
2; Selected calcium alginate fibre fineness is 3.3dtex, and length is 40mm; Vinal is water-soluble fibre, and in water, solution temperature is 90 degree, and length is 33-41mm.
Embodiment 3
As shown in Figure 1, the based composite dressing for medical use of the application calcium alginate fibre of embodiment 3, comprises surface layer 1, intermediate layer 2 and wound-contacting layer 3.Described medical dressing can use conventional packing material.
The surface layer of embodiment 3 is non-woven fabric of polyester fiber, and grammes per square metre is 50g/m
2, intermediate layer 2 and wound-contacting layer 3 are calcium alginate fibre and vinal mixing needle fabric, and wherein, the calcium alginate fibre content in intermediate layer is 70%, and vinal content is 30%, and intermediate layer grammes per square metre is 80g/m
2, the calcium alginate fibre content of wound-contacting layer is 80%, and vinal content is 20%, and wound-contacting layer grammes per square metre is 50g/m
2.
The based composite dressing for medical use grammes per square metre of embodiment 3 is 180g/m
2; Selected calcium alginate fibre fineness is 3.3dtex, and length is 40mm; Vinal is water-soluble fibre, and in water, solution temperature is 90 degree, and length is 33-41mm.
The surface layer non-woven fabric of polyester fiber of each embodiment is commercially available prod above.
The surface layer 1 of each embodiment, intermediate layer 2 and wound-contacting layer 3 are cut according to the width of required dressing and length above, and each layer laminated structure after cutting together, realizes interlayer ultrasonic bonds with ultrasonic bonds machine and connect.The parameter setting of ultrasound bonder is: pressure roller rotating speed 2.5r/s, output 3.2w, platen pressure 15MPa.
The intermediate layer processing process of each embodiment is above: calcium alginate fibre, vinal are weighed → mix → shredding → combing → acupuncture.
Wherein, described shredding is carried out twice; During described combing, the parameter of carding machine is: feeding speed is 0.51r/min, and licker-in rotating speed is 520.83r/min, and cylinder rotating speed is 500r/min, and doffing speed is 8.33r/min, and going out net spee is 4.4m/min; Described needing machine acupuncture parameter is: bestock 2000 pieces/m, and rotating speed is 200r/min.
The wound-contacting layer processing process of each embodiment is above: calcium alginate fibre, vinal are weighed → mix → shredding → combing → acupuncture → hot rolling.
Wherein, described shredding is carried out twice; During described combing, the parameter of carding machine is: feeding speed is 0.51r/min, and licker-in rotating speed is 520.83r/min, and cylinder rotating speed is 500r/min, and doffing speed is 8.33r/min, and going out net spee is 4.4m/min; Described needing machine acupuncture parameter is: bestock 2000 pieces/m, and rotating speed is 200r/min; Described hot-rolled temperature is 190 DEG C, and hot rolling is carried out twice.
The specific embodiments more of the present invention more than provided, only for illustrating technical scheme of the present invention, do not limit the scope of the application's claim protection.
Liquid-absorbent for this based composite dressing for medical use intermediate layer is tested:
According to the processing technique of intermediate layer " calcium alginate fibre, vinal weigh → mix → shredding → combing → acupuncture ", produce grammes per square metre respectively and be 60g/m
2, calcium alginate fibre and vinal mixed proportion be respectively 40/60,55/45,70/30 three groups of non-weaving cloths, carry out liquid-absorbent test according to China's pharmaceuticals industry standard " YY/T0471.1 contact Wound dressing experimental technique Part I: liquid-absorbent ".
Test result display fiber mixing ratio be 40/60 the average imbibition quality of non-weaving cloth be 9.9289g/100cm
2, fiber mixing ratio be 55/45 the average imbibition quality of non-weaving cloth be 10.2031g/100cm
2, fiber mixing ratio be 70/30 the average imbibition quality of non-weaving cloth be 9.0825g/cm
2can find out fiber mixing ratio be 40/60 non-weaving cloth average imbibition quality and fiber mixing ratio be 55/45 non-weaving cloth close and be better than the non-weaving cloth that fiber mixing ratio is 70/30, fibres visible mixed proportion is that the minimum and imbibition quality of its calcium alginate fibre component content of non-weaving cloth of 40/60 is close to the highest.
Non-weaving cloth more than in test is equal to intermediate layer of the present invention, and therefore intermediate layer of the present invention optimum fiber mixed proportion is 40/60.
Test for this based composite dressing for medical use wound-contacting layer gelling characteristic:
According to the processing technique " calcium alginate fibre, vinal weigh → mix → shredding → combing → acupuncture → hot rolling " of wound-contacting layer, produce grammes per square metre respectively and be 40g/m
2, calcium alginate fibre and vinal mixed proportion be respectively 80/20,90/10 and 99/1 three groups of non-weaving cloths, according to the gelling characteristic part of detecting in China's pharmaceuticals industry standard " YY/T0471.1 contact Wound dressing experimental technique Part I: liquid-absorbent ", gelling characteristic test is carried out to three groups of non-weaving cloths.
Test result display 0.2g fiber mixing ratio be 80/20 non-weaving cloth produce gel quality be 1.4870g, the fiber mixing ratio of 0.2g be 90/10 the gel quality that produces of non-weaving cloth to be the fiber mixing ratio of 1.6419g, 0.2g be 99/1 the gel quality that produces of non-weaving cloth be 1.5802g.Can find out fiber mixing ratio be 80/20 the gel content that produces of alginate fibre/polyvinyl alcohol nonwovens and fiber mixing ratio be 99/1 alginate fibre non-weaving cloth be more or less the same, but cardability and brute force improve.Non-weaving cloth more than in test is equal to wound-contacting layer of the present invention, and therefore wound-contacting layer optimum fiber mixed proportion of the present invention is 80/20.
Below adopt above-mentioned optimum fiber mixed proportion respectively for intermediate layer and wound-contacting layer and grammes per square metre different this based composite dressing for medical use sample in intermediate layer carries out the result (seeing the following form) of liquid-absorbent test respectively:
Test is carried out according to China's pharmaceuticals industry standard " YY/T0471.1 contact Wound dressing experimental technique Part I: liquid-absorbent ".
Its non-woven fabric of polyester fiber surface layer grammes per square metre of each sample of carrying out testing is 50g/m
2, intermediate layer the ratio of calcium alginate fibre/vinal is 40/60, the ratio of the calcium alginate fibre/vinal of wound-contacting layer is 80/20.
The each sample carrying out testing is with the grammes per square metre grouping of three kinds, intermediate layer, and often organize 5, dimensions is identical.
Subordinate list illustrates that this based composite dressing for medical use has very strong fluid absorbent, and illustrates that intermediate layer has outstanding effect to fluid absorbent, and intermediate layer grammes per square metre can carry out selection design according to the number of wound fluid and the order of severity.
Claims (8)
1. apply the based composite dressing for medical use of calcium alginate fibre, comprise surface layer, intermediate layer and wound-contacting layer, it is characterized in that: described surface layer is non-woven fabric of polyester fiber, intermediate layer and wound-contacting layer are calcium alginate fibre and vinal mixing needle fabric, the calcium alginate fibre content in described intermediate layer is 40-70%, vinal content is 30-60%, and intermediate layer grammes per square metre is 30-80g/m
2, the calcium alginate fibre content of described wound-contacting layer is 80-99%, vinal content is 1-20%, and wound-contacting layer grammes per square metre is 30-50g/m
2.
2. based composite dressing for medical use according to claim 1, is characterized in that: intermediate layer calcium alginate fibre content is 40%, vinal content is 60%.
3. based composite dressing for medical use according to claim 1, is characterized in that: wound-contacting layer calcium alginate fibre content is 80%, vinal content is 20%.
4. based composite dressing for medical use according to claim 1, is characterized in that: described based composite dressing for medical use grammes per square metre is 100-180g/m
2.
5. based composite dressing for medical use according to claim 1, is characterized in that: the non-woven fabric of polyester fiber grammes per square metre of described surface layer is 40-50g/m
2.
6. based composite dressing for medical use according to claim 1, is characterized in that: described calcium alginate fibre fineness is 3.3dtex, and length is 40mm.
7. based composite dressing for medical use according to claim 1, is characterized in that: described vinal is water-soluble fibre, and in water, solution temperature is 90 degree, and length is 33-41mm.
8. based composite dressing for medical use according to claim 1, is characterized in that: described surface layer, between intermediate layer and wound-contacting layer be ultrasonic bonds connect.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310179722.3A CN103239754B (en) | 2013-05-15 | 2013-05-15 | Composite medical dressing using calcium alginate fibers |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310179722.3A CN103239754B (en) | 2013-05-15 | 2013-05-15 | Composite medical dressing using calcium alginate fibers |
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| CN103239754A CN103239754A (en) | 2013-08-14 |
| CN103239754B true CN103239754B (en) | 2015-03-18 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105193547A (en) * | 2015-08-24 | 2015-12-30 | 泰州市榕兴医疗用品股份有限公司 | Medical dressing special for treating diabetes |
| CN112679628B (en) * | 2020-12-24 | 2021-10-26 | 张家口健垣精准医学有限公司 | Medical dressing based on alginate fibers and preparation method thereof |
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| US8551517B2 (en) * | 2008-12-16 | 2013-10-08 | Kimberly-Clark Worldwide, Inc. | Substrates providing multiple releases of active agents |
| EP2228078A1 (en) * | 2009-03-09 | 2010-09-15 | Pietrasanta Pharma S.p.A. | Chitosan and polyurethane foam based medication, production process thereof and use thereof in the wound management |
| CN102600018B (en) * | 2012-03-31 | 2013-07-03 | 华南理工大学 | Medical dressing with cooling function and wound healing prompting function and preparation method of medical dressing |
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