CN103239553A - Traditional Chinese medicine composition for treating anaphylactoid purpura - Google Patents
Traditional Chinese medicine composition for treating anaphylactoid purpura Download PDFInfo
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Abstract
The invention provides a traditional Chinese medicine composition for treating anaphylactoid purpura. The traditional Chinese medicine composition comprises the following components in parts by weight: 9-15 parts of codonopsis pilosula, 12-18 parts of radix astragali, 9-15 parts of bighead atractylodes rhizome, 7-11 parts of angelica sinensis, 9-15 parts of poria cocos, 9-15 parts of prepared rehmannia root, 12-18 parts of radix paeoniae alba, 4-6 parts of szechuan lovage rhizome, 5-7 parts of tangerine peel, 12-18 parts of agrimonia pilosa, 9-15 parts of Chinese dates and 5-7 parts of liquorice. Compared with the prior art, the traditional Chinese medicine composition is capable of treating internal pathogenic factors of anaphylactoid purpura according to different symptoms and treating both symptoms and root causes, and is quick in curative effect, low in cost, free of toxic or side effects and remarkable in effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, more particularly, relate to a kind of Chinese medicine composition for the treatment of anaphylactoid purpura.
Background technology
Anaphylactoid purpura is a kind of allergic disease of blood capillary.Clinical characters is skin petechia, ecchymosis, is distributed in extremity more and stretches side and buttocks, and symmetry occurs in batches, and stomachache and arthralgia etc. are often arranged.Its pathogenesis mainly is owing to body causes that to some allergin generation allergy the permeability of capillary wall and fragility increase.Primary disease is more common in child and youth.Clinical skin-type (seeing at most), abdomen type, joint type, kidney type, mixed type five types of being divided into.As timely diagnosis and treatment, prognosis bona.Anaphylactoid purpura belongs to the traditional Chinese medical science " blood disorder ", " macule ", " hematohidrosis " category.Existing prescription is all not good enough on cure rate, treatment means and treatment cost, can not reach gratifying effect.Prior art needs a kind of respond well Chinese medicinal composition preparation to replace above-mentioned therapeutic scheme.
Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition for the treatment of anaphylactoid purpura, it is at the inherent pathogenic factor of anaphylactoid purpura, distinguishes that disease executing control, and with strong points, curative effect is fast, and cost is low, and has no side effect, and can reach to play good prevention effect.
In order to realize above-mentioned purpose, the present invention by the following technical solutions: a kind of Chinese medicine composition for the treatment of anaphylactoid purpura, in weight portion, comprise following component: Radix Codonopsis 9-15, Radix Astragali 12-18, Rhizoma Atractylodis Macrocephalae 9-15, Radix Angelicae Sinensis 7-11, Poria 9-15, Radix Rehmanniae Preparata 9-15, Radix Paeoniae Alba 12-18, Rhizoma Chuanxiong 4-6, Pericarpium Citri Reticulatae 5-7, Herba Agrimoniae 12-18, Fructus Jujubae 9-15, Radix Glycyrrhizae 5-7.
The Analysis on Mechanism of Chinese medicine composition thing of the present invention:
Radix Codonopsis: sweet in the mouth; Property is put down.Return spleen; Lung meridian.Strengthening the spleen and tonifying the lung, supplementing QI for promoting the production of body fluid.Cure mainly weakness of the spleen and stomach, anorexia and loose stool, limbs fatigue, the deficiency of the lung breath with cough, breathe hard spontaneous perspiration, feeble QI two and lose all cards." Bencao Congxin ": invigorating the spleen and replenishing QI and taste relieving thirst and restlessness.
The Radix Astragali: sweet, tepor.Return lung, spleen, liver, kidney channel.The effect of invigorating QI to consolidate the body surface resistance, hidroschesis detoxification, granulation promoting, diuresis, detumescent.It is weak to be used for the treatment of the deficiency of vital energy, sinking of QI of middle-JIAO, and the chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, the exterior deficiency spontaneous perspiration, carbuncle is difficult bursts, and burst for a long time and do not hold back, blood deficiency and yellow complexion, interior-heat is quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.
The Rhizoma Atractylodis Macrocephalae: bitter in the mouth; Sweet; Warm in nature.Return spleen; The stomach warp.Invigorating the spleen and benefiting QI; The dampness diuretic; Hidroschesis.Be used for deficiency-weakness of spleen-QI; Spiritlessness and weakness." herbal classic is met former ": the Rhizoma Atractylodis Macrocephalae, it is living that the expectorant diuretic is controlled anemofrigid-damp arthralgia with there being the dehumidifying benefit dry, dead flesh convulsion subcutaneous ulcer, the blood between the waist umbilicus that looses, reaching chong channel is disease, the merit of contrary gas pain in the abdomen; Making ripely then has and middle QI invigorating, slakes thirst and help produce saliva, and the hidroschesis heat extraction advances diet, antiabortive effect.
Radix Angelicae Sinensis: warm in nature, hide sweet, hot.Return liver, the heart, spleen channel.Enrich blood and invigorate blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.Materia Medica of Decoction: Radix Angelicae Sinensis, few the moon of starting with, with its heart master blood also; It is lunar to go into foot, wraps up in blood also with its spleen; Go into the sufficient the moon of fainting, with its blood stored in the liver also.
Poria: slightly sweet flavor is flat, goes into the heart, lung, spleen channel.Eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming." herbal classic ": the contrary gas of the main breast side of body, melancholy is angerd frightened heresy and is probably throbbed with fear, knot pain under the heart, cold and heat stuffy sensation with restlessness, cough with dyspnea, mouthful burnt dry tongue, diuresis.
Radix Rehmanniae Preparata: sweet in the mouth; Warm in nature.Return liver; Kidney channel.It is moist to enrich blood; The benefit essence is filled out marrow.It is sallow to be used for the blood tiger; Dizzy cardiopalmus; Menoxenia; Collapse more than; Hepatic and renal YIN deficiency." detailed outline ": fill out bone marrow, longue meat, promoting generation of vital essence and blood, tonifying five ZANG-organs, internal injury deficiency, promoting blood circulation, sharp knowledge, black beard and hair, man's five kinds of strain and seven kinds of impairment, woman's damaging the spleen and stomach threatened abortion, irregular menorrhea, tire produces all kinds of diseases and ailments.
The Radix Paeoniae Alba: hardship; Acid; Be slightly cold.Return liver; Spleen channel.Nourish blood and seek; Relieving spasm to stop pain; The yin fluid astringing suppressing the hyperactive liver.Be used for menoxenia; Abdominal pain during menstruation; Metrorrhagia; Spontaneous perspiration; Night sweat; Side of body rib epigastric pain; Limb pain twin; Headache; Dizzy." herbal classic ": main pathogen stomachache, broken hard long-pending except arthralgia due to stagnation of blood, control cold and heat hernia abdominal mass, pain relieving, diuresis, QI invigorating.
Rhizoma Chuanxiong: acrid in the mouth, warm in nature.Return liver, gallbladder, pericardium channel.Blood circulation promoting and blood stasis dispelling; Activating QI to alleviate the depression; Wind-expelling pain-stopping." herbal classic ": main apoplexy is gone into the brain headache, arthralgia due to cold, and the clonic spasm of the muscle emergency, the gold wound, married woman's blood closes loss of fecundity.
Pericarpium Citri Reticulatae: warm in nature, acrid in the mouth, bitter in the mouth.Go into spleen channel, stomach warp, lung meridian.Regulating qi-flowing for strengthening spleen, in the accent, dampness is reduced phlegm." daily book on Chinese herbal medicine ": can loose and to rush down, can temperature can mend, the diaphragm gas that can disappear, reduce phlegm saliva and spleen antitussive, logical five types of stranguria.
Herba Agrimoniae: bitter in the mouth, puckery, property is flat.Return lung, liver, spleen channel.Astringing to arrest bleeding, dysentery relieving, parasite killing.Cure mainly spitting of blood, spit blood, hematuria is had blood in stool, dysentery, and bleeding not during menses, impairment caused by overstrain is taken off power, carbuncle, traumatic injury, wound hemorrhage." BAICAO mirror ": the therapeutic method to keep the adverse QI flowing downwards is invigorated blood circulation, reason all kinds of diseases and ailments, and feeling of fullness looses; Fall and pounce on haematemesis, metrorrhagia, dysentery, discharging fresh blood stool.
Fructus Jujubae: sweet; Temperature.Spleen; The stomach warp.Tonifying the spleen and stomach; Replenishing QI and blood; Tranquilizing mind; Transfer battalion to defend.Be used for weakness of the spleen and stomach, insufficiency of vital energy and blood, anorexia and loose stool, fatigue and weakness, palpitation and insomnia, woman hysteria, disharmony of nutrient QI with defensive QI." book on Chinese herbal medicine is new again ": invigorating the spleen and replenishing QI, the nourishing kidney warming the stomach is controlled the deficiency of YIN.
Radix Glycyrrhizae: property is flat, and sweet in the mouth is returned 12 warps.Invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.
The Scolopendra powder: salty, hot, temperature.Poisonous.Return liver, spleen, lung meridian.Relieve internal heat, relieving spasm by calming endogenous wind, move back scorching pain relieving, eliminating stagnation.
The cause of disease of anaphylactoid purpura mostly is heat in blood and stops up the heresy of containing the sense six climate exopathogens of holding concurrently, and pathogenic heat are fought mutually with heat in blood, the absurd row of forcing blood; Or be plain body hyperactivity of fire caused by deficiency of YIN, multiple hinder because of exopathogen or some food, medicine, so that pathogenic heat stop up and hold back venation the absurd row of forcing blood and a speckle.Pathological change is the body of heat in blood, invades excessive space between skin and muscles because of the heresy of wind-fire noxious dampness, gos deep into nutrient blood, and pathogenic heat are fought mutually with heat in blood, the thermal burn channels, and hyperamization liquid does not follow Chang Dao and overflows outside arteries and veins; Or because eating the product of discomfort.It is not normal to cause transporting and transforming function of the spleen and stomach, damp and hot interior giving birth to, and forcing blood is excessive; Or plain body hyperactivity of fire caused by deficiency of YIN, the deficiency of YIN then channels lose to be supported, and hyperactivity of fire then venation is injured, and hyperamization is overflow outside arteries and veins and is fallen ill.In addition, deficiency-weakness of spleen-QI, the insufficiency of the spleen blood of can not uniting, the deficiency of vital energy can not be taken the photograph blood, but also the excessive arteries and veins of hyperamization is sent out speckle outward.At the anaphylactoid purpura due to the insufficiency of the spleen blood oozing from the body openings or subcuta neous tissue, the traditional Chinese medical science think temper lose empty, the insufficiency of the spleen blood of then not uniting, the deficiency of vital energy is not then taken the photograph blood, so the skin ecchymosis that shows effect repeatedly, obstinate disease is so the speckle color is light dim; QI and blood loss, muscle arteries and veins bones of the body collectively are lost in scholar and are supported, thus pale complexion, the lazy speech of tachypnea, shortness of breath and palpitation; Insufficiency of the spleen inability of food and drink to be digested and transported, so tastelessness is indigestion and loss of appetite, stool or half congealed; Enlarged tongue matter is light red, and deficient and thready pulse is resembling of insufficiency of the spleen anemia.
The person of choosing in the side, replenishing QI to invigorate the spleen is taken the photograph the blood hemostasis.Radix Codonopsis, Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI, Radix Astragali invigorating QI to consolidate the body surface resistance, Radix Angelicae Sinensis are transferred blood, and Poria oozes invigorating the spleen and regulating the stomach, and Radix Rehmanniae Preparata benefit essence is filled out marrow, and the Radix Paeoniae Alba is nourished blood and seeks, Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling, Pericarpium Citri Reticulatae regulating qi-flowing for strengthening spleen, Herba Agrimoniae astringing to arrest bleeding, Fructus Jujubae replenishing QI and blood, the Radix Glycyrrhizae invigorating the spleen and replenishing QI coordinating the actions of various ingredients in a prescription of holding concurrently.Play altogether full side, and replenishing QI to invigorate the spleen is taken the photograph the blood hemostasis, balance body negative and positive.At the anaphylactoid purpura due to the insufficiency of the spleen blood oozing from the body openings or subcuta neous tissue, distinguish that disease executing control, curative effect is fast, and cost is low, determined curative effect, prevention effect is remarkable, doublely takes stopgap measures this.
Chinese medicine composition dosage form of the present invention can adopt tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.Preferably, can adopt solution, granule, pill and capsule.
Result of use
50 patients (birth 8-15 year) are used the Chinese medicine composition for the treatment of anaphylactoid purpura of the present invention, and 1 course for the treatment of of continued treatment (1 month), wherein 19 examples are cured fully, and it is normal that index is recovered; 26 routine remissions; Invalid 5 examples, overall effective percentage reaches 90%, and does not have recurrence.
Example:
The patient 1: Huang, and the women, 8 years old, purpura showed effect repeatedly, long-term chronic skin ecchymosis, the speckle color is light dim, pale complexion, the lazy speech of tachypnea, stool or half congealed, shortness of breath and palpitation.Enlarged tongue matter is light red, and tongue is greasy in vain, deficient and thready pulse.Be anaphylactoid purpura after diagnosing.Take 2 weeks of Chinese medicine composition of the present invention, ecchymosis alleviates, and the pale complexion symptom takes a turn for the better, and continues two weeks of medication, and other symptoms also all disappear, recovery from illness.Follow up a case by regular visits to after four months, do not have recurrence.
The patient 2: Yuan, and the male, 10 years old, ecchymosis in flakes appearred in the extremity symmetry, protracted course of disease, tastelessness is indigestion and loss of appetite, and enlarged tongue matter is light red, greasy fur, thready pulse.Doctor trained in Western medicine medication treatment is not felt any better, after take 2 weeks of Chinese medicine composition of the present invention, ecchymosis reduces, and continues 2 weeks of medication, ecchymosis thoroughly disappears, other symptoms also all disappear, recovery from illness did not have recurrence in 2 months so far.
The patient 3: Deng, and the male, 13 years old, purpura was more, and color is dim, is symmetrically distributed in extremity, stool or half congealed, shortness of breath and palpitation, with epistaxis, body of the tongue is light red, and tongue is greasy in vain, thready pulse.The back uses Chinese medicine composition of the present invention to treat, and after 2 weeks, purpura reduces, and continues 2 weeks of medication, and other symptoms all disappear, and recovery from illness does not have recurrence so far.
The patient 4: Ma, and the women, 12 years old, anaphylactoid purpura, the color dimness, bleeding from the gum, tastelessness is indigestion and loss of appetite, pale complexion.Tongue is greasy in vain, red tongue, thready pulse.Use Chinese medicine composition of the present invention to treat, after 2 weeks, purpura begins to reduce, and bleeding from the gum disappears, and continues medication and consolidates the course for the treatment of half, and other symptoms also all disappear, and do not have recurrence so far.
The specific embodiment
In order to understand the present invention better, below by embodiment the present invention is described.
Embodiment 1
A kind of Chinese medicine composition for the treatment of anaphylactoid purpura in weight portion, comprises following component: Radix Codonopsis 9, the Radix Astragali 12, the Rhizoma Atractylodis Macrocephalae 9, Radix Angelicae Sinensis 7, Poria 9, Radix Rehmanniae Preparata 9, the Radix Paeoniae Alba 12, Rhizoma Chuanxiong 4, Pericarpium Citri Reticulatae 5, Herba Agrimoniae 12, Fructus Jujubae 9, Radix Glycyrrhizae 5.
Its preparation method is:
In weight portion, get Radix Codonopsis 9, the Radix Astragali 12, the Rhizoma Atractylodis Macrocephalae 9, Radix Angelicae Sinensis 7, Poria 9, Radix Rehmanniae Preparata 9, the Radix Paeoniae Alba 12, Rhizoma Chuanxiong 4, Pericarpium Citri Reticulatae 5, Herba Agrimoniae 12, Fructus Jujubae 9, Radix Glycyrrhizae 5; Above-mentioned Chinese medicine composition is cleaned, and decontamination is put into container and is added water and do not have medical material to soak, and after 30 minutes, big fire decocts to boiling, and slow fire was endured 1 hour slowly then; Medicine juice is leached, bag distribution packaging, one bag of 200ml sooner or later respectively obeys one bag.
Embodiment 2
A kind of Chinese medicine composition for the treatment of anaphylactoid purpura in weight portion, comprises following component: Radix Codonopsis 15, the Radix Astragali 18, the Rhizoma Atractylodis Macrocephalae 15, Radix Angelicae Sinensis 11, Poria 15, Radix Rehmanniae Preparata 15, the Radix Paeoniae Alba 18, Rhizoma Chuanxiong 6, Pericarpium Citri Reticulatae 7, Herba Agrimoniae 18, Fructus Jujubae 15, Radix Glycyrrhizae 7.
Its preparation method is:
In weight portion, get Radix Codonopsis 15, the Radix Astragali 18, the Rhizoma Atractylodis Macrocephalae 15, Radix Angelicae Sinensis 11, Poria 15, Radix Rehmanniae Preparata 15, the Radix Paeoniae Alba 18, Rhizoma Chuanxiong 6, Pericarpium Citri Reticulatae 7, Herba Agrimoniae 18, Fructus Jujubae 15, Radix Glycyrrhizae 7; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, afterwards be concentrated into the clear paste of relative density 1.10-1.20 with concentrator, get 2/3 clear paste 120 ℃ of following spray dryinges, get the clear paste powder, powder is mixed with residue 1/3 clear paste, granulate; The packing of granule racking machine namely gets granule.
Embodiment 3
A kind of Chinese medicine composition for the treatment of anaphylactoid purpura in weight portion, comprises following component: Radix Codonopsis 12, the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 12, Radix Angelicae Sinensis 9, Poria 12, Radix Rehmanniae Preparata 12, the Radix Paeoniae Alba 15, Rhizoma Chuanxiong 5, Pericarpium Citri Reticulatae 6, Herba Agrimoniae 15, Fructus Jujubae 12, Radix Glycyrrhizae 6.
Its preparation method is:
In weight portion, get Radix Codonopsis 12, the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 12, Radix Angelicae Sinensis 9, Poria 12, Radix Rehmanniae Preparata 12, the Radix Paeoniae Alba 15, Rhizoma Chuanxiong 5, Pericarpium Citri Reticulatae 6, Herba Agrimoniae 15, Fructus Jujubae 12, Radix Glycyrrhizae 6; Cleaning, drying mix above-mentioned medical material, and pulverizing with pulverizer is 150-180 order fine powder, and add suitable Mel and mix, the pellet processing machine pill, cold drying, packing namely gets pill.
Embodiment 4
A kind of Chinese medicine composition for the treatment of anaphylactoid purpura in weight portion, comprises following component: Radix Codonopsis 12, the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 12, Radix Angelicae Sinensis 9, Poria 12, Radix Rehmanniae Preparata 12, the Radix Paeoniae Alba 15, Rhizoma Chuanxiong 5, Pericarpium Citri Reticulatae 6, Herba Agrimoniae 15, Fructus Jujubae 12, Radix Glycyrrhizae 6.
Its preparation method is:
In weight portion, get Radix Codonopsis 12, the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 12, Radix Angelicae Sinensis 9, Poria 12, Radix Rehmanniae Preparata 12, the Radix Paeoniae Alba 15, Rhizoma Chuanxiong 5, Pericarpium Citri Reticulatae 6, Herba Agrimoniae 15, Fructus Jujubae 12, Radix Glycyrrhizae 6; Cleaning, drying mix above-mentioned medical material, and per kilogram adds about 10L water, and 0.5-1 at a simmer hour, big fire was fried in shallow oil 1-2 hour; Get decocting liquid and cross 150 mesh sieves, afterwards be concentrated into the clear paste of relative density 1.10-1.20 with concentrator, get 2/3 clear paste 120 ℃ of following spray dryinges, get the clear paste powder, powder is mixed with residue 1/3 clear paste, granulate; Granule is made the 0.4g/ capsules with the capsule filler.
Claims (4)
1. a Chinese medicine composition for the treatment of anaphylactoid purpura is characterized in that, in weight portion, comprise following component: Radix Codonopsis 9-15, Radix Astragali 12-18, Rhizoma Atractylodis Macrocephalae 9-15, Radix Angelicae Sinensis 7-11, Poria 9-15, Radix Rehmanniae Preparata 9-15, Radix Paeoniae Alba 12-18, Rhizoma Chuanxiong 4-6, Pericarpium Citri Reticulatae 5-7, Herba Agrimoniae 12-18, Fructus Jujubae 9-15, Radix Glycyrrhizae 5-7.
2. Chinese medicine composition according to claim 1 is characterized in that, in weight portion, preferably comprises following component: Radix Codonopsis 12, the Radix Astragali 15, the Rhizoma Atractylodis Macrocephalae 12, Radix Angelicae Sinensis 9, Poria 12, Radix Rehmanniae Preparata 12, the Radix Paeoniae Alba 15, Rhizoma Chuanxiong 5, Pericarpium Citri Reticulatae 6, Herba Agrimoniae 15, Fructus Jujubae 12, Radix Glycyrrhizae 6.
3. Chinese medicine composition according to claim 1 is characterized in that, described Chinese medicine composition adopts tablet, granule, pill, capsule, solution, oral liquid, buccal tablet, granule, electuary, powder, suspensoid, powder.
4. Chinese medicine composition according to claim 1 is characterized in that, described Chinese medicine composition preferably adopts solution, granule, pill and capsule.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117562895A (en) * | 2024-01-17 | 2024-02-20 | 中国中医科学院中药研究所 | Application of atractylenolide I in preparation of medicine for preventing/treating allergic purpura |
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| WO2005095412A1 (en) * | 2004-04-01 | 2005-10-13 | Kureha Corporation | Antiallergic agent |
| CN102973819A (en) * | 2011-09-07 | 2013-03-20 | 林凡新 | Traditional Chinese medicine prescription for treatment of allergic purpura |
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2013
- 2013-04-23 CN CN2013101419802A patent/CN103239553A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2005095412A1 (en) * | 2004-04-01 | 2005-10-13 | Kureha Corporation | Antiallergic agent |
| CN102973819A (en) * | 2011-09-07 | 2013-03-20 | 林凡新 | Traditional Chinese medicine prescription for treatment of allergic purpura |
Non-Patent Citations (1)
| Title |
|---|
| 医学教育网 HTTP://WWW.MED66.COM/NEW/201208/ZJ201208106494.SHTML: "《医学教育网》", 10 August 2012, article "过敏性紫癜-中医" * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN117562895A (en) * | 2024-01-17 | 2024-02-20 | 中国中医科学院中药研究所 | Application of atractylenolide I in preparation of medicine for preventing/treating allergic purpura |
| CN117562895B (en) * | 2024-01-17 | 2024-04-02 | 中国中医科学院中药研究所 | Application of atractylenolide I in preparation of medicine for treating allergic purpura |
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Application publication date: 20130814 |