CN103238846B - Alpha-linolenic acid soft capsule - Google Patents
Alpha-linolenic acid soft capsule Download PDFInfo
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- CN103238846B CN103238846B CN201310212491.1A CN201310212491A CN103238846B CN 103238846 B CN103238846 B CN 103238846B CN 201310212491 A CN201310212491 A CN 201310212491A CN 103238846 B CN103238846 B CN 103238846B
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Abstract
The invention relates to a health care food having the effects of resisting inflammation, preventing thrombosis, reducing blood fat and relaxing blood vessel, and in particular relates to an alpha-linolenic acid soft capsule. The alpha-linolenic acid soft capsule is composed of the following raw materials: 78-82 g of high-purity alpha-linolenic acid, 1.5-2 g of vitamin E and 16-20.5 g of gelatin. The alpha-linolenic acid soft capsule prepared according to the formula provided by the invention is a health care food which remains various nutrient constituents; and the high-purity alpha-linolenic acid has good effects of resisting inflammation, preventing thrombosis, reducing blood fat and relaxing blood vessel.
Description
Technical field
The present invention relates to a kind of health food with anti-inflammatory, antithrombotic, reducing blood lipid, vasodilator effect, particularly relate to a kind of alpha-linolenic acid soft capsule.
Background technology
Alpha-linolenic acid is a kind of polyunsaturated fatty acid, form human body brain cell and histiocytic important component, human body self can not synthesize alpha-linolenic acid, meals are relied on to obtain, after it enters human body, under the catalytic action of enzyme, change into eicosapentaenoic acid and DHA, prevention and containment three height are played an important role.The current domestic existing health food containing alpha-linolenic acid mainly contains two aspect problems: one is alpha-linolenic acid in most product is the alpha-linolenic acid of nature, and the alpha-linolenic acid of nature contains triglycerides harmful in a large number; Two are alpha-linolenic acids in minority product is esterified, but all prepares-leukotrienes by urea adduct method, has certain residual urea, produces harm to health.
Summary of the invention
The present invention is directed to above-mentioned the deficiencies in the prior art, provide a kind of have highly purified, biologically active is high, absorption rate is high, without residual urea, the alpha-linolenic acid soft capsule that has no side effect.
The technical scheme that the present invention solves the problems of the technologies described above is as follows: a kind of alpha-linolenic acid soft capsule, and its raw material consists of:
High-purity alpha-linolenic acid 78-82g
Vitamin E 1.5-2g
Gelatin 16-20.5g
Wherein the purifying technique of high-purity alpha-linolenic acid is:
1) carry out pretreatment to alpha-linolenic acid feedstock oil raw material, described pre-treatment step comprises: alpha-linolenic acid feedstock oil raw material admission inspection, impurity elimination and coarse filtration;
2) alpha-linolenic acid feedstock oil after pretreatment is ethyl esterified, undertaken reacting by alpha-linolenic acid feedstock oil and ethanol and react by alpha-linolenic acid feedstock oil and ethanol, reaction condition: under vacuum state, 75 DEG C of reaction 1-2 hour, obtain Alpha-ethyl linolenate;
3) by above-mentioned Alpha-ethyl linolenate at 0 DEG C in-30 DEG C of conditions, after gradient freezing crystallization, then through three grades of molecular clocks, obtain the high-purity alpha-linolenic acid that purity is 90.1-92.2%.
Described alpha-linolenic acid feedstock oil is the one in linseed oil, Purple Perilla Seed Oil, Eucommia Oil, Seabuckthorn Oil, Zanthoxylum essential oil, fructus cannabis oil.
Above-mentioned alpha-linolenic acid feedstock oil, vitamin E and gelatin three kinds of raw materials all can commercially availablely be buied.
The preparation method of alpha-linolenic acid soft capsule of the present invention is: take high-purity alpha-linolenic acid, vitamin E and gelatin respectively according to above-mentioned weight proportion, according to existing soft capsule preparation technology, is processed into capsule health food containing.
The alpha-linolenic acid soft capsule obtained according to formula of the present invention is a kind of health food, retains various nutritional labeling; Highly purified alpha-linolenic acid, has good anti-inflammatory, antithrombotic, reducing blood lipid, vasodilatory effect; Pure physics prepares highly purified alpha-linolenic acid method, removes traditional urea clathrate process, and product, without any residual urea, has no side effect.
Detailed description of the invention
Be described principle of the present invention and feature below, example, only for explaining the present invention, is not intended to limit scope of the present invention.
Embodiment 1
The preparation of high-purity alpha-linolenic acid: carry out pretreatment to alpha-linolenic acid feedstock oil raw material, described pre-treatment step comprises: alpha-linolenic acid feedstock oil raw material admission inspection, impurity elimination and coarse filtration; Alpha-linolenic acid feedstock oil after pretreatment is ethyl esterified, reacts, reaction condition: under vacuum state by alpha-linolenic acid feedstock oil and ethanol, not higher than 75 DEG C of reaction 1-2 hour, obtains ethyl linolenate; By above-mentioned ethyl linolenate in 0 DEG C to-30 DEG C of conditions, after gradient freezing crystallization, then through three grades of molecular clocks, obtain the high-purity alpha-linolenic acid that purity is 90.1-92.2%.
Described alpha-linolenic acid feedstock oil is the one in linseed oil, Purple Perilla Seed Oil, Eucommia Oil, Seabuckthorn Oil, Zanthoxylum essential oil, fructus cannabis oil.
The preparation of alpha-linolenic acid soft capsule: by the gelatin of the vitamin E of the high-purity alpha-linolenic acid of 78 g, 1.5g, 20.5g conveniently method for making make soft capsule, more namely can be made into alpha-linolenic acid soft capsule of the present invention through the inspection of semifinished product, packaging and finished product exfactory inspection.
Embodiment 2
The method for making of high-purity alpha-linolenic acid is with embodiment 1.By the gelatin of the vitamin E of the high-purity alpha-linolenic acid of 81.5 g, 2g, 16g conveniently method for making make soft capsule, more namely can be made into alpha-linolenic acid soft capsule of the present invention through the inspection of semifinished product, packaging and finished product exfactory inspection.
Embodiment 3
The method for making of high-purity alpha-linolenic acid is with embodiment 1.By the gelatin of the vitamin E of the high-purity alpha-linolenic acid of 82 g, 1.6g, 16.4g conveniently method for making make soft capsule, more namely can be made into alpha-linolenic acid soft capsule of the present invention through the inspection of semifinished product, packaging and finished product exfactory inspection.
Embodiment 4
The method for making of high-purity alpha-linolenic acid is with embodiment 1.By the gelatin of the vitamin E of the high-purity alpha-linolenic acid of 78 g, 2g, 20g conveniently method for making make soft capsule, more namely can be made into alpha-linolenic acid soft capsule of the present invention through the inspection of semifinished product, packaging and finished product exfactory inspection.
The present invention can summarize with other the concrete form without prejudice to spirit of the present invention or principal character.Therefore, no matter from which point, above-mentioned embodiment of the present invention all can only be thought explanation of the present invention and can not limit the present invention, claims indicate scope of the present invention, and scope of the present invention is not pointed out in above-mentioned explanation, therefore, any change in the implication suitable with claims of the present invention and scope, all should think to be included in the scope of claims.
Claims (2)
1. an alpha-linolenic acid soft capsule, is characterized in that, its raw material consists of:
High-purity alpha-linolenic acid 78-82g
Vitamin E 1.5-2g
Gelatin 16-20.5g
Wherein the purifying technique of high-purity alpha-linolenic acid is:
1) carry out pretreatment to alpha-linolenic acid feedstock oil raw material, described pre-treatment step comprises: alpha-linolenic acid feedstock oil raw material admission inspection, impurity elimination and coarse filtration;
2) alpha-linolenic acid feedstock oil after pretreatment is ethyl esterified, reacts, reaction condition: under vacuum state by alpha-linolenic acid feedstock oil and ethanol, not higher than 75 DEG C of reactions 2 hours, obtains Alpha-ethyl linolenate;
3) by above-mentioned Alpha-ethyl linolenate at 0 DEG C in-30 DEG C of conditions, after gradient freezing crystallization, then through three grades of molecular clocks, obtain the high-purity alpha-linolenic acid that purity is 90.1-92.2%.
2. a kind of alpha-linolenic acid soft capsule according to claim 1, is characterized in that, described alpha-linolenic acid feedstock oil is the one in linseed oil, Eucommia Oil, Seabuckthorn Oil, Zanthoxylum essential oil, fructus cannabis oil.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN201310212491.1A CN103238846B (en) | 2013-05-31 | 2013-05-31 | Alpha-linolenic acid soft capsule |
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| CN201310212491.1A CN103238846B (en) | 2013-05-31 | 2013-05-31 | Alpha-linolenic acid soft capsule |
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| CN103238846A CN103238846A (en) | 2013-08-14 |
| CN103238846B true CN103238846B (en) | 2015-03-18 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT201900022764A1 (en) * | 2019-12-03 | 2021-06-03 | Skb Llc | SKIN CARE PRODUCT AND PROCEDURE FOR ITS REALIZATION |
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| CN103598587A (en) * | 2013-11-20 | 2014-02-26 | 山西振东制药股份有限公司 | Health-care food with blood fat reduction assistance effect and preparation method thereof |
| CN105707568A (en) * | 2014-12-04 | 2016-06-29 | 兰州大学 | Alpha-linolenic acid soft capsule with function of auxiliarily lowering blood lipids and preparation method thereof |
| CN104522649B (en) * | 2014-12-18 | 2016-08-17 | 润科生物工程（福建）有限公司 | A kind of DHA algal oil soft capsule containing Oleum Perillae and preparation method thereof |
| CN104643065A (en) * | 2015-01-28 | 2015-05-27 | 郑州大学 | Hawthorn omega-3 soft capsule and preparation method thereof |
| CN104886565A (en) * | 2015-05-07 | 2015-09-09 | 张海龙 | Eucommia ulmoides brain strengthening oral liquid and a production method thereof |
| CN106038508A (en) * | 2016-06-17 | 2016-10-26 | 上海春芝堂生物制品有限公司 | Plant capsule shell material, soft capsules, and preparation method and application of plant capsule shell material and soft capsule |
| CN108851058A (en) * | 2018-07-13 | 2018-11-23 | 德瑞美医药生物技术盐城有限公司 | A kind of multivitamin minerals soft capsule and preparation method thereof rich in alpha-linolenic acid |
| CN112006942A (en) * | 2019-05-30 | 2020-12-01 | 吉林正昇康生物工程有限公司 | Essential oil composition and application thereof |
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Effective date of registration: 20180517 Address after: 264006 Tianjin North Road, Yantai economic and Technological Development Zone, Shandong 19 Patentee after: YANTAI YANYUAN KEMA HEALTH INDUSTRY CO., LTD. Address before: 264006 Jinsha River Road, Yantai Development Zone, Shandong Province, No. 11 Patentee before: Yanyuan Kormark Biotechnology Development Co., Ltd. |
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