CN103230580A - Traditional Chinese medicine composition for preventing and treating infectious serositis of duck - Google Patents

Abstract

The invention aims to provide a traditional Chinese medicine composition for preventing and treating infectious serositis of duck, which is non-tolerance, safe and effective. Pericarpium granati, majoram, tongol aster herb, Chinese tuliptree bark and lindera setchuenensis gamble are used as the monarch drug for bacteriostasis, detoxicating and anti-inflammation; euonymus alatus, coriander, common wedgelet fern herb, oriental blechnum frond and centipede minima are used as the ministerial drug for detoxicating, antipyresis, antiviral and adjusting gastrointestinal motility; tree of heaven ailanthus leaf, moutan bark, menthe, anisodus luridus and eriocarpous glochidion leaf are used as the excipient for resisting stress and improving micro circulation; and folium isatidis, berchemia lineate, Peruvian groundcherry herb, ginger and shepherdspurse herb are used as the adjuvant drug. The traditional Chinese medicine composition is non-tolerance, safe and effective.

Description

A kind of Chinese medicine composition of preventing and treating infectious serositis in duck

Technical field

The present invention relates to the field of Chinese medicines, specifically a kind of Chinese medicine composition of preventing and treating infectious serositis in duck.

Background technology

Infectious serositis in duck has another name called pest of duck Bacillus pasteurii disease, new duck disease or duck septicemia, is a kind of chronic or acute septic infectious disease of the infringement duckling that caused by the pest of duck pasteurellosis bacillus.It is characterized in that causing duckling cellulose pericarditis, perihepatitis, airsacculitis and arthritis.This disease is distributed in all over the world widely, causes death, loses weight and superseded provisions duck is already caused enormous economic loss.

Present precautionary approach is as follows:

Strengthen feeding and management, note ventilation, environmental drying, the sanitation and hygiene of duck shed, often sterilization, the feeding regime of employing all-in and all-out.

Thiamphenicol (bar Garrick-Kuiwen District poultry institute) medicine etc. has good prevention effect to this disease.At duckling susceptible age in days, add in the drinking-water and add 0.025%～0.05% sulphaquinoxaline in 0.2%～0.25% sulfamethazine or the feedstuff and carry out preventive usage, can prevent this disease or reduce this sick mortality rate.Cillimycin and penicillin associating subcutaneous injection preferably can be done drug sensitivity test before the medication during treatment.

Be used for the vaccine that prophylactic immunization should disease, mainly contain two kinds of oil emulsion adjuvant Emulsion Seedling and Paracox at present both at home and abroad.The formalin inactivated vaccine gives 1 week duckling in age twice subcutaneous immunity inoculation, and its protective rate can reach more than 86%, has the better prevention effect.

Can all have Drug resistance by medicine earlier, can not use for a long time.

Summary of the invention

The purpose of this invention is to provide a kind of Chinese medicine composition that has no drug resistance, prevents and treats infectious serositis in duck safely and effectively, with Pericarpium Granati, Adeps Bovis seu Bubali, Aster dubius (Thunb.) Onno, Cortex Liriodendri Chinensis, Radix Linderae Setchuenensis be that monarch drug is antibacterial, detoxifcation, antiinflammatory, be ministerial drug detoxifcation, analgesic, antiviral, adjusting gastrointestinal motility with Ramulus Euonymi, Herba Coriandri, Folium Stenolomatis, Folium Blechni orientalis, Herba Centipedae, being accessory drugs anti-stress, microcirculation improvement with Folium ailanthi, Cortex Moutan, Herba Menthae, Rhizoma Scopoliae Japonicae, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi), is adjuvant drug with Folium Isatidis, Radix berchemiae lineatae, Fructus Seu Herba Pubescentis, Rhizoma Zingiberis Recens, Herba Capsellae.

A kind of Chinese medicine composition of preventing and treating infectious serositis in duck is characterized in that, is made up of the raw material of following weight portion:

Pericarpium Granati 15-20 part, Adeps Bovis seu Bubali 15-20 part, Aster dubius (Thunb.) Onno 15-20 part, Cortex Liriodendri Chinensis 15-20 part, Radix Linderae Setchuenensis 15-20 part, Ramulus Euonymi 10-15 part, Herba Coriandri 10-15 part, Folium Stenolomatis 10-15 part, Folium Blechni orientalis 10-15 part, Herba Centipedae 10-15 part, Folium ailanthi 5-10 part, Cortex Moutan 5-10 part, Herba Menthae 5-10 part, Rhizoma Scopoliae Japonicae 5-10 part, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 5-10 part, Folium Isatidis 1-5 part, Radix berchemiae lineatae 1-5 part, Fructus Seu Herba Pubescentis 1-5 part, Rhizoma Zingiberis Recens 1-5 part, Herba Capsellae 1-5 part.

Preparation method:

By formula proportion above-mentioned Chinese medicine oven dry is ground into 300-400 purpose fine powder and uses ultrasound wave homogenize 10-30 minute under 0-10 ℃ of temperature, packing is finished product.

Can be used as feed additive and use, also can submit from fear with water 1:1.

A kind of Chinese medicine composition of preventing and treating infectious serositis in duck is characterized in that, is made up of the raw material of following weight portion:

Pericarpium Granati 16-18 part, Adeps Bovis seu Bubali 16-18 part, Aster dubius (Thunb.) Onno 16-18 part, Cortex Liriodendri Chinensis 16-18 part, Radix Linderae Setchuenensis 16-18 part, Ramulus Euonymi 11-14 part, Herba Coriandri 11-14 part, Folium Stenolomatis 11-14 part, Folium Blechni orientalis 11-14 part, Herba Centipedae 11-14 part, Folium ailanthi 6-8 part, Cortex Moutan 6-8 part, Herba Menthae 6-8 part, Rhizoma Scopoliae Japonicae 6-8 part, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 6-8 part, Folium Isatidis 2-4 part, Radix berchemiae lineatae 2-4 part, Fructus Seu Herba Pubescentis 2-4 part, Rhizoma Zingiberis Recens 2-4 part, Herba Capsellae 2-4 part.

A, elder generation crystallize into powder with Aster dubius (Thunb.) Onno, Adeps Bovis seu Bubali, Herba Menthae distillation;

B, get the surplus stock medicine again and put into soak with ethanol, heat is extracted 2 times, becomes the extractum shape, is component 1;

C, medicinal residues extracting in water 1 time, thickening filtration are the extractum shape, are component 2;

D, above-mentioned two kinds of extractum are condensed into pasty state, add the powder that a step obtains, add Mel and be twisted into pill.

As preferably, it is characterized in that, among the described step b, get crude drug and add 60-90% soak with ethanol 1-2 hour that 5-10 doubly measures, heating extraction 2 times, each 1-2 hour, get supernatant, merge extractive liquid,, the 80-120 order filters, and is the ultrafiltration post ultrafiltration of 5000-10000 again through the molecular weight that dams, 1.36 extractum when ultrafiltrate concentrating under reduced pressure relative density is 80 ℃, heating concentrates, and 30 minutes～45 minutes, extracts active component, concentrated solution is settled into pasty state, mass continues heating and is concentrated into the extractum shape, and stand for standby use becomes component 1;

As preferably, it is characterized in that among the described step c, medicinal residues add 5-10 times of water gaging and soaked 1-2 hour, extract 1 time in 1-1.5 hour, as component 2.

Adding 20-30% in the feedstuff gets final product.

A kind of Chinese medicine composition of preventing and treating infectious serositis in duck is characterized in that, is made up of the raw material of following weight portion:

17 parts of Pericarpium Granatis, 17 parts of Adeps Bovis seu Bubalis, 17 parts of Aster dubius (Thunb.) Onno, 17 parts of Cortex Liriodendri Chinensiss, 17 parts of Radix Linderae Setchuenensiss, 12 parts of Ramulus Euonymis, 12 parts of Herba Coriandris, 12 parts of Folium Stenolomatiss, 12 parts of Folium Blechni orientaliss, 12 parts of Herba Centipedae, 7 parts of Folium ailanthi, 7 parts of Cortex Moutans, 7 parts of Herba Menthaes, 7 parts of Rhizoma Scopoliae Japonicae, 7 parts of Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi)s, 3 parts of Folium Isatidiss, 3 parts of Radix berchemiae lineataes, 3 parts of Fructus Seu Herba Pubescentiss, 3 parts in Rhizoma Zingiberis Recens, 3 parts in Herba Capsellae.

The present invention relates to pharmacology and the property of medicine of Chinese medicine:

Pericarpium Granati:

[nature and flavor]

Sour and astringent, temperature, poisonous.

1. " property of medicine opinion ": " sour in the mouth is nontoxic."

2. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " cold in nature, sour-puckery flavor."

3. " detailed outline ": " sour and astringent, prevent, nontoxic."

4. " Guangxi Chinese medicine ": " bitter and puckery flavor, warm in nature, poisonous." ^[

[return through]

Go into large intestine, lung, kidney channel.

1. " Thunder God is concocted property of medicine solution ": " go into large intestine, kidney two warps."

2. " book on Chinese herbal medicine brief points ": " lunar, the meridian of Foot-SHAO YIN of starting with.

[function cures mainly]

Astringing intestine to stop diarrhea, hemostasis, anthelmintic.Control chronic diarrhea, chronic dysentery is had blood in stool, proctoptosis, spermatorrhea, metrorrhagia, leukorrhagia, abdominal pain due to worm stagnation, scabies.

1. " not Lu ": " treat dysentery, the leak-stopping essence."

2. " property of medicine opinion ": " control muscles and bones wind, the waist foot is unsuccessful, the anxious pain of walking contraction.Main astringing intestine to stop diarrhea ends red white dysentery.Extracting juice ends under the order tear, controls Lou smart."

3. supplement to the Herbal: " main ascarid.Decoction."

4. " the southern regions of the Yunnan Province book on Chinese herbal medicine ": " control with the passing of time watery diarrhea, simmer clothes with frying Saccharum Sinensis Roxb., control the dysentery pus and blood again, the large intestine hematochezia." " fried in shallow oil with Fructus Aristolochiae and controlled children's's infantile malnutrition worm."

5. " book on Chinese herbal medicine covers bamboo fish trap ": " reason dental caries."

6. " detailed outline ": " antidiarrheal dysentery, hematochezia, proctoptosis, metrorrhagia leukorrhagia."

7. " the SHENGCAO property of medicine is wanted fully ": " control the tumor skin ulcer, wash colic."

8. " it is former that book on Chinese herbal medicine is asked ": " wash the speckle mange."

9. " medicinal herbs among the people of science ": " drive away hook, cestode.

Aster dubius (Thunb.) Onno:

[nature and flavor] hardship, flat.

A little less than [function cures mainly] tonify deficiency.Control consumptive disease and hinder halitosis, gingival hemorrhage, vicious impetigo.

[usage and consumption] is for oral administration: boil Ovum Anas domestica and eat.External: grind into powder and spread or bright product are smash deposited.

[choosing side]

1. a little less than the tonify deficiency: thin medicine, the Rhizoma Anemarrhenae, Radix Achyranthis Bidentatae, each five money of Datlily root.Frying in shallow oil green shell Ovum Anas domestica eats.

2. control gingival hemorrhage and halitosis sialorrhea: thin medicine is ground into powder, gets and puts the affected part in right amount.Gargle with salt water or washing water of rice earlier before the drug of topical application.

3. control vicious impetigo: bright thin medicine is an amount of.Mash the bag affected part, change dressings every day three to four times.

[attached side]

1. the headache that cures cold, bones and muscles pain, rhinocleisis: Herba Erigerontis is decocted in water for oral dose.(" Kunming medical herbs commonly used among the people ")

2. control the paralysis of poliomyelitis sequela and encephalitis sequela: Herba Erigerontis two to three money.Grind into powder, the Steamed chicken egg is eaten.(" Kunming medical herbs commonly used among the people ")

3. control infantile malnutrition, ascariasis, flu, costalgia: Herba Erigerontis three to five money.Be decocted in water for oral dose.(" Yunnan Chinese herbal medicine ")

4. control toothache: the fresh erigeron breviscapus herb, mash with brown sugar and apply sore spot.(" Yunnan Chinese herbal medicine ")

5. control furunculosis, furuncle: Herba Erigerontis, mash external application.(" Kunming medical herbs commonly used among the people ")

Adeps Bovis seu Bubali:

Acrid in the mouth, cool in nature, nontoxic, herb can be used as medicine, and has the effect of urine detumescence of clearing away heat and expelling pathogen in the exterior, regulating QI to expel dampness.

Clinically treat diseases such as yellow cellulitis, heatstroke, heating, vomiting, acute gastroenteritis, stomachache for flu-prevention, its expelling cold and relieving exterior syndrome function is better than Herba Menthae.Background information shows that Adeps Bovis seu Bubali contains more than 30 kind of antimicrobial compound to " phytochemistry and plant species are learned " of United States Department of Agriculture (USDA), is a kind of potential natural antibiotics and medicine growth promoter.

All herbal medicine, but flu-prevention, control diseases such as heatstroke, flu, headache heavy sensation of the body, stomachache, vomiting, chest and diaphragm distension, vapour lock dyspepsia, food stagnation of child abdominal distention, diarrhoea, menorrhagia, bleeding not during menses, skin itching and edema, its cold expelling is delivered function, is better than Herba Menthae especially.

Cortex Liriodendri Chinensis:

[nature and flavor] suffering; Warm in nature

[function cures mainly] expelling wind and removing dampness; The cold expelling cough-relieving.The main air pain of dampness syndrome; The cough due to wind and cold

[usage and dosage] is for oral administration: fry in shallow oil soup, 9～15g.

[pharmacological action] antibacterial action heartwood ethanol extraction has antibacterial action, effective to staphylococcus aureus, smegma mycobacteria, Candida albicans and aspergillus niger etc., prove that further antibiotic effective ingredient is dehydroglaucin (dehydroglaucine).

Radix Linderae Setchuenensis:

[meridian distribution of property and flavor] is bitter, cold, goes into heart channel.

[function cures mainly] " the mount emei medicine is planted ": " apply and control sore."

Ramulus Euonymi:

Winged euonymus is named again that Ramulus Euonymi, terrible arrow, June are insulted, four sides cutting edge of a knife or a sword, castor dustpan bavin, four ribs tree, Gallus jabouillei strip, halberd, JIANZHONGXIAO, anaesthetic on four sides.Branch or aliform appurtenance for the tool aliform thing of Celastraceae plant winged euonymus.Can adopt the whole year, extract branch after, remove twig and leaf, dry.Or collect its aliform thing, dry.There is removing blood stasis to stimulate the menstrual flow; Removing toxic substances and promoting subsidence of swelling; The effect of parasite killing.

[nature and flavor] hardship; Hot; Cold.

1. " herbal classic ": bitter in the mouth, cold.

2. " WU Pu Bencao ": hardship, nontoxic.

3. " property of medicine opinion ": slightly poisonous.

4. " Japan hanako materia medica ": sweet-puckery flavor.

5. " detailed outline ": sour-puckery flavor.

[return through]: Liver Channel.

1. " book on Chinese herbal medicine brief points ": go into meridian of Foot-JUE YIN.

[effect and effect] removing blood stasis stimulates the menstrual flow; Removing toxic substances and promoting subsidence of swelling; Parasite killing.Primary symptom abdominal mass caking; Trusted subordinate's pain; Amenorrhea; Dysmenorrhea; Metrorrhagia and metrostaxis; The stasis of blood stagnated and suffered from abdominal pain puerperal; Retention of lochia; Hernia; The severe and migratory arthralgia arthralgia pain; Skin ulcer is swollen; Traumatic pain; Abdominal pain due to worm stagnation; Burn and scald; Venom.

1. " herbal classic ": main woman's metrorrhagia hematochezia, abdominal distention sweating.

2. " not Lu ": main attacked by pestiferous factors stomachache, remove tapeworm, the skin pathogenic wind toxic that disappears is swollen, makes in the moon and separating.

3. " property of medicine opinion ": broken old blood, tire falls.Main attacked by pestiferous factors waist stomachache.

4. Tang Materia Medica: treat married woman's vim and vigour.

5. " Japan hanako materia medica ": logical menstruation, broken crux, hemostasis is collapsed, leukorrhagia, kills the alvus worm, reaches blood strand belly pain in puerperal.

6. " the real figure of general name examines ": control toxic swelling.

Eliminating stasis to stop pain is stimulated the menstrual flow in [clinical practice] promoting the circulation of blood.Be used for menoxenia, puerperal abdominalgia with blood stasis, traumatic injury swells and ache.

Herba Coriandri:

[another name]: Herba Coriandri, Yuan Mu, coriander, Caulis et Folium Brassicae campestris, former Sui, garden Sui, coriander, Coriander, Herba Coriandri, tabernaemontanus bulrush Sui, Yan Sui Cai, Yan Pueraria lobota grass, Caulis et folium pavettae hongkongensis, salt cooked food, salt shine, and the silver whiskers Herba Coriandri cries " Herba Coriandri " the earliest, and the beginning is stated from the 《 Jiayou Bencao ".

[ The property of medicine]Suffering, temperature.Attach to the lung and stomach meridians.

[effect]Herba Coriandri suffering, temperature are returned lung, spleen channel; Have the diaphoresis rash, removing stagnancy of indigested food and making QI downward, be amusing and in effect; Cure mainly the measles initial stage, appear and freely do not reach stagnant, the diseases such as appetite is not opened, proctoptosis of food.

1. measles: 3 strains of Herba Coriandri LIANXU, 3 of Corm Eleocharitiss, Lacca 3 grams add the more than half bowl of water, fry in shallow oil filtered juice after 15 minutes, divide clothes 2 times, obey once every 4 hours, obeying during eruption, can prevent complication; Or Herba Coriandri 500 gram, after water is boiled, Herba Coriandri is boiled 1～2 boils and get final product, then water is poured in the basin, smoke with steam earlier, after wash brothers with water, can control that measles should can not go out or rash goes out not saturating.

2. cold syndrome of the stomach is bitterly: Herba Coriandri leaf 1000 grams, and 500 milliliters of wines immerse Herba Coriandri, and defoliation is drunk after 3 days, and clothes are 15 milliliters during pain.

3. hemorrhoid are swollen aches and proctoptosis: Herba Coriandri is boiled soup, smokes with this soup and washes the affected part.

4. dyspepsia, inappetence ceriander seed (fruit) 6 restrain, Pericarpium Citri Reticulatae, six bent each 9 gram, and 3 in Rhizoma Zingiberis Recens is decocted in water for oral dose.

5. hypertension: with bright 10 grams, add Radix Puerariae 10 grams and be decocted in water for oral dose, each 1 time sooner or later, obey 50 milliliters at every turn, obey 10 days is 1 course for the treatment of, to treating hypertension auxiliary curative effect is arranged.

6. oh make a mistake: Herba Ocimi (Herba Ocimi Pilosi) leaf 6 grams (bright leaf doubles), 3 in Rhizoma Zingiberis Recens, boiled water steeps or fries in shallow oil one and boils, while hot clothes.

7. chest and diaphragm is full vexed: ceriander seed is ground into powder, each 3 grams, and boiled water is swallowed.

8. vomiting: it is spoonful that the bright grass of regurgitation is smash juice in right amount, and two spoons of Caulis Sacchari sinensis juices add decoction being taken warmly, 2 times on the one.

9. cornea is given birth to nebula: seed 1-2 grain, clean, and include in eye adjoins, close order a moment later, the seed bulking, the adhesion order is searched.

10. Common Cold: Herba Coriandri 30 grams, maltose 15 grams, with half bowl of rice water, sugar steams and dissolves the back clothes.

Folium Stenolomatis:

[nature and flavor]: " Guangxi Chinese medicinal herbal ": little hardship, cold, nontoxic.

[function cures mainly]: the effect of Folium Stenolomatis, heat clearing away, detoxifcation, dampness removing, hemostasis.Control anemopyretic cold, the heatstroke sun stroke is had loose bowels, dysentery, and nebulousurine, leucorrhea, cough is spitted blood, and has blood in stool hematuria, ulcerative gingivitis, carbuncle.

Source: be herb or the root stock of Lindsaeaceae plant Folium Stenolomatis.

Main effect:

1. " high medicated cap medicine is planted ": root stock: quench is brought down a fever.

2. " Guizhou side's medicine among the people collection ": herb: cough-relieving.The wind that cures the wound flu; Nine sub-infectionss are controlled in external, the detumescence poison.

3. " Guangxi Chinese medicinal herbal ": leaf: control heat syndrome cough and spit blood, red-white dysentery, detoxifcation; The external treatment traumatic injury is hemorrhage, burn due to hot liquid or fire, cards such as the mashed meat of skin infection; Root: control also Hakuri.

4. Guangzhou army " Chinese herbal medicine handbook commonly used: herb: heat clearing away, detoxifcation, dampness removing.Control influenza, flu, cough, tonsillitis, parotitis, enteritis, dysentery, skin eczema.

Folium ailanthi:

[return through] lung meridian

[chemical composition of Chinese materia medica]: leaf contains globulariacitrin (rutin), afzelin (afzelin), quercitrin (quercitrin), Isoquercitrin (isoquercitrin), nimbecetin (kaempferol), bark element (quercetin) and aminoacid (amino acid).

[effect]: heat clearing and damp drying; Parasite killing

[textual criticism]: come from Compendium of Material Medica section and belong to classification: Simarubaceae

[curing mainly]: damp and hot dysentery; Have loose bowels; Dysentery; Eczema; The skin ulcer scabies; Furuncle and phyma.

Rhizoma Scopoliae Japonicae:

[meridian distribution of property and flavor] is warm in nature, flavor fiber crops: severe toxicity is arranged.Go into the heart, liver, lung meridian.

[function cures mainly] controls eating accumulation, dysphagia and regurgitation.

1. supplement to the Herbal: " QI invigorating is made light of one's life by commiting suicide, hard muscles and bones."

2. " Kangxu's investigate things of a little free time volume ": " property is warm, and the strengthening the spleen stomach is easy to digestion, does not tell well the person, and polyphagia is useful."

3. " property of medicine is examined ": " heat clearing away pathogenic wind expelling."

4. " detailed outline is picked up any lost article from the road ": " the tonneau large intestine, the dyspepsia that disappears is controlled dysphagia and regurgitation."

Folium Blechni orientalis:

[nature and flavor] hardship; Cold

[return through] Liver Channel

[function cures mainly] heat-clearing and toxic substances removing.Main carbuncle furuncle

[usage and dosage] external: an amount of, bright product are smash deposited

[each family discuss] " wild medicine is planted figure and is said ": smash edema of the dorsum of the foot pain, can subside a swelling, draw out pus by applying a plaster to the affected part, granulation promoting

Herba Centipedae:

[effect] dispersing wind-cold, clearing the nasal passage, cough-relieving, detoxifcation.

[curing mainly] flu; Headache; Nasal sinusitis; Nasal polyp; Cough; Sore throat; Deaf; Conjunctivitis; Malaria; Rheumatic arthralgia; Traumatic injury; Toxic swelling; Scabies. The treatment rhinitis:Comprise acute rhinitis, chronic simple rhinitis, hypertrophic rhinitis, allergic rhinitis etc.Transference cures such as headache after most of case medications, nasal obstruction or alleviate.Usage: Herba Centipedae is ground into fine powder sucks the nostril, every day for several times; Or with Cotton Gossypii soak wring out after, bag medicated powder a little, be rolled into slice plug nose, take out every day 1 time after 20-30 minute; Or make the ointment sliver, and place nasal cavity, take out after 1 hour.After the medication except from the beginning of sneeze is arranged, shed tears with rhinorrhea, surplus having no adverse reaction. The treatment malaria:Myriogyne minuta is made injection (every milliliter contains crude drug 2g), outbreak injection in preceding 2 hours 1 time, be used in conjunction 3.Each dosage: 1-3 year 2ml, 4-8 year 3ml, 9-14 year 4ml, 5ml more than 15 years old.Observe existing disease patient 187 examples of various malaria, through 1-3 medication, 175 examples of fully recovering (93.6%).Compare with chloroquine, uncle's quinoline matched group, curative effect does not have marked difference.There are 3 example injection backs to take place to feel sick and slight vomiting in the treatment, die away after the drug withdrawal. The treatment pertussis:According to the observation of example surplus 300, cure rate is generally about 90%.Mostly after medication in 24 hours typical paroxysmal spasmodic cough begin to alleviate.Healing time, weak point person 3-6 days, elder 10-15 days. The treatment soft tissue injury:With the Herba Centipedae pulverize, the adult is each with 2-3 money (children's reduces by half), with yellow wine 6-8 two (not alcohol user with drinks half and half), brown sugar 1-2 two with boiling (the back Mi Gai that boils does not make disappointing), decoction being taken warmly after the filtration; Medicinal residues spread on affected part while hot.Also available powder 3-6g every day, or smash juice with the careless 1-2 two of aquatic foods, divide and take after mixing it with water with heat wine for 3 times.Soft tissue injurys such as treatment breast, the back of the body, waist (comprise get injured by a fall, injure, dampen, sprain etc.), all effective.Observe according to tens of examples, greatly more than recovery from illness in 1-2 after the medication days.Have the pain between boiling after the agent except the stomachache patient obeys wine, generally have no side effect.Also have and bright Myriogyne minuta is made injection (every 1500g bright medicine make 500ml) make acupoint injection therapy, diseases such as treatment articular sprain, lumbar muscle strain, rheumatalgia are observed 94 examples, 31 examples of fully recovering, and 60 examples that take a turn for the better, effective percentage reaches 97%.Usage: in pain spot or selecting the acupoints according to the channel injection, each 0.2-0.5ml, the next day 1 time, general 3-5 time is a course for the treatment of.

Cortex Moutan: Paeonia suffruticosa not only has ornamental value, but also has very high medical value.The root of Paeonia suffruticosa is processed into " Cortex Moutan ", is famous and precious Chinese herbal medicine.Its cold nature, acrid in the mouth, nontoxic, go into the heart, liver, kidney three warps, dissipating blood stasis blood is arranged, purify the blood and blood, pain relieving, the effect of stimulating the menstrual flow, bring high blood pressure down in addition, the effect of anti-inflammation, clothes can be lengthened the life by beneficial body for a long time.The regulating liver-QI that nourishes blood, is applicable to chloasma faciei at the strongly fragrant blood stasis dispelling that looses, and skin aging is often drunk the QI and blood lung of living, and appearance is ruddy, improves menoxenia, and dysmenorrhea is ended sweating due to debility, night sweat.

Herba Menthae:

[meridian distribution of property and flavor] cool in nature, acrid in the mouth;

The effect of [function] irritation causes trachea to produce new secretion, and makes the mucus of stiff be easy to get rid of, so the effect of eliminating the phlegm, sterilizing is arranged.

Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi):

[meridian distribution of property and flavor] bitter but sweet flavor is puckery, and property is flat;

[effect] dispelling wind and dampness, dissipating blood stasis, hemostasis, detumescence.Cure mainly acute gastroenteritis, dysentery, rheumatic arthritis, traumatic injury, wound hemorrhage, dermatitis rhus, eczema, dermatitis; Control Toxicodendron verniciflnum (Stokes) F. A. Barkley (Rhus verniciflua Stokes) allergy, paddy field dermatitis, skin pruritus, exfoliative dermatitis, urticaria, eczema: the bright leaf of Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) or cured leaf, decoction being used as a lotion.

Folium Isatidis:

[nature and flavor] gas is cold, and mildly bitter flavor is salty."

[return through] goes into liver, the heart, stomach warp.

[function] heat clearing away, detoxifcation, removing heat from blood, hemostasis.Control epidemic febrile disease intenseness of heat excessive thirst, influenza, acute infectious hepatitis, bacillary dysentery, acute gastroenteritis, acute pneumonia, erysipelas is spitted blood epistaxis, jaundice, dysentery, sore throat, aphtha, swollen ulcer drug.Folium Isatidis is mainly used in pyretic toxicity and sends out diseases such as speckle, erysipelas, laryngopharynx swelling and pain, aphtha of the mouth and tongue, sore and toxic.

Radix berchemiae lineatae:

Has subduing swelling and detoxicating, hemostatic analgesia, effects such as expelling wind and removing dampness

[meridian distribution of property and flavor] bitter in the mouth, little puckery, property is flat.GUIXIN, lung meridian.

[effect cures mainly] subduing swelling and detoxicating; Hemostatic analgesia; Expelling wind and removing dampness.Cure mainly the carbuncle furunculosis; The cough spitting of blood; Digestive tract hemorrhage; Traumatic injury; Scald; Rheumatic ostalgia; Acute toothache.

Fructus Seu Herba Pubescentis:

[nature and flavor] " Sichuan Chinese medicinal herbal ": " cold in nature, bitter in the mouth is nontoxic."

[function cures mainly] eliminating dampness by diuresis, parasite killing.The subcutaneous ulcer of harnessing the Yellow River, dysuria, chronic cough and asthma, infantile malnutrition, scrofula, epidemic blisters, eczema.Clearing away heat-damp and promoting diuresis; Passive phlegm and relieving cough; Hard masses softening and resolving.Main jaundice due to damp-heat; Dysuria; Chronic cough and asthma; Infantile malnutrition; Scrofula; Epidemic blisters; Eczema; Furuncle and phyma is " classification medical herbs " 1.: the detoxifcation parasite killing, leaf is controlled epidemic blisters." 2. " Tian Bao book on Chinese herbal medicine ": control children's's tympanites, infantile malnutrition." 3. " Sichuan Chinese medicinal herbal ": diuresis, the mass beside the umbilicus that disappears, the steaming consumptive fever of boning.The subcutaneous ulcer of harnessing the Yellow River, dysuria, chronic cough dyspnea with rapid respiration; Be coated with children's's impetigo and skin herpes simplex outward.Single better with fruit effectiveness." 4. Guangzhou army " Chinese herbal medicine handbook commonly used: cold, fever, laryngopharynx swelling and pain; Acute bronchitis; The eczema toxic swelling."

Rhizoma Zingiberis Recens:

[Nature and flavor] hot, tepor, return lung taste warp

[effect] relieving the exterior syndrome by diaphoresis, warming middle-JIAO to arrest vomiting, warming the lung to relieve cough, solving toxin of fish and crab is separated poison of drug; Deliver, cold expelling, preventing or arresting vomiting is opened expectorant, carbuncle skin ulcer.

Herba Capsellae:

[nature and flavor] are sweet flat, have and spleen, diuretic, the effect of stopping blooding, making eye bright." Mingyi Bielu " record " main sharp irritability and in." " daily book on Chinese herbal medicine " year " removing heat in the liver for improving eyesight." Compendium of Material Medica record " makes eye bright stomach reinforcing." have very high medical value, have and spleen, diuretic, the effect of stopping blooding, making eye bright, be usually used in treating the swollen disease such as painful of postpartum hemorrhage, dysentery, edema, enteritis, gastric ulcer, cold, fever, conjunctival congestion.

The specific embodiment:

Embodiment 1, prescription:

Pericarpium Granati 15g, Adeps Bovis seu Bubali 15g, Aster dubius (Thunb.) Onno 15g, Cortex Liriodendri Chinensis 15g, Radix Linderae Setchuenensis 15g, Ramulus Euonymi 10g, Herba Coriandri 10g, Folium Stenolomatis 10g, Folium Blechni orientalis 10g, Herba Centipedae 10g, Folium ailanthi 5g, Cortex Moutan 5g, Herba Menthae 5g, Rhizoma Scopoliae Japonicae 5g, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 5g, Folium Isatidis 1g, Radix berchemiae lineatae 1g, Fructus Seu Herba Pubescentis 1g, Rhizoma Zingiberis Recens 1g, Herba Capsellae 1g;

Preparation method:

By formula proportion above-mentioned Chinese medicine oven dry is ground into 300-400 purpose fine powder and uses ultrasound wave homogenize 10-30 minute under 0-10 ℃ of temperature, packing is finished product.

Can be used as feed additive and use, also can submit from fear with water 1:1.

Embodiment 2, prescription:

Pericarpium Granati 16g, Adeps Bovis seu Bubali 16g, Aster dubius (Thunb.) Onno 16g, Cortex Liriodendri Chinensis 16g, Radix Linderae Setchuenensis 16g, Ramulus Euonymi 11g, Herba Coriandri 11g, Folium Stenolomatis 11g, Folium Blechni orientalis 11g, Herba Centipedae 11g, Folium ailanthi 6g, Cortex Moutan 6g, Herba Menthae 6g, Rhizoma Scopoliae Japonicae 6g, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 6g, Folium Isatidis 2g, Radix berchemiae lineatae 2g, Fructus Seu Herba Pubescentis 2g, Rhizoma Zingiberis Recens 2-4g, Herba Capsellae 2g;

Preparation method:

A, elder generation crystallize into powder with Aster dubius (Thunb.) Onno, Adeps Bovis seu Bubali, Herba Menthae distillation;

B, get the surplus stock medicine again and put into soak with ethanol, heat is extracted 2 times, becomes the extractum shape, is component 1;

C, medicinal residues extracting in water 1 time, thickening filtration are the extractum shape, are component 2;

D, above-mentioned two kinds of extractum are condensed into pasty state, add the powder that a step obtains, add Mel and be twisted into pill.

As preferably, it is characterized in that, among the described step b, get crude drug and add 60-90% soak with ethanol 1-2 hour that 5-10 doubly measures, heating extraction 2 times, each 1-2 hour, get supernatant, merge extractive liquid,, the 80-120 order filters, and is the ultrafiltration post ultrafiltration of 5000-10000 again through the molecular weight that dams, 1.36 extractum when ultrafiltrate concentrating under reduced pressure relative density is 80 ℃, heating concentrates, and 30 minutes～45 minutes, extracts active component, concentrated solution is settled into pasty state, mass continues heating and is concentrated into the extractum shape, and stand for standby use becomes component 1;

As preferably, it is characterized in that among the described step c, medicinal residues add 5-10 times of water gaging and soaked 1-2 hour, extract 1 time in 1-1.5 hour, as component 2.

Adding 20-30% in the feedstuff gets final product.

Embodiment 3, prescription:

Pericarpium Granati 17g, Adeps Bovis seu Bubali 17g, Aster dubius (Thunb.) Onno 17g, Cortex Liriodendri Chinensis 17g, Radix Linderae Setchuenensis 17g, Ramulus Euonymi 12g, Herba Coriandri 12g, Folium Stenolomatis 12g, Folium Blechni orientalis 12g, Herba Centipedae 12g, Folium ailanthi 7g, Cortex Moutan 7g, Herba Menthae 7g, Rhizoma Scopoliae Japonicae 7g, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 7g, Folium Isatidis 3g, Radix berchemiae lineatae 3g, Fructus Seu Herba Pubescentis 3g, Rhizoma Zingiberis Recens 3g, Herba Capsellae 3g;

Preparation method is identical with embodiment 1.

Embodiment 4, prescription:

Pericarpium Granati 18g, Adeps Bovis seu Bubali 18g, Aster dubius (Thunb.) Onno 18g, Cortex Liriodendri Chinensis 18g, Radix Linderae Setchuenensis 18g, Ramulus Euonymi 14g, Herba Coriandri 14g, Folium Stenolomatis 14g, Folium Blechni orientalis 14g, Herba Centipedae 14g, Folium ailanthi 8g, Cortex Moutan 8g, Herba Menthae 8g, Rhizoma Scopoliae Japonicae 8g, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 8g, Folium Isatidis 4g, Radix berchemiae lineatae 4g, Fructus Seu Herba Pubescentis 4g, Rhizoma Zingiberis Recens 4g, Herba Capsellae 4g;

Preparation method:

A, elder generation crystallize into powder with Aster dubius (Thunb.) Onno, Adeps Bovis seu Bubali, Herba Menthae distillation;

B, get the surplus stock medicine again and put into soak with ethanol, heat is extracted 2 times, becomes the extractum shape, is component 1;

C, medicinal residues extracting in water 1 time, thickening filtration are the extractum shape, are component 2;

D, above-mentioned two kinds of extractum are condensed into pasty state, add the powder that a step obtains, add Mel and be twisted into pill.

As preferably, it is characterized in that, among the described step b, get crude drug and add 60-90% soak with ethanol 1-2 hour that 5-10 doubly measures, heating extraction 2 times, each 1-2 hour, get supernatant, merge extractive liquid,, the 80-120 order filters, and is the ultrafiltration post ultrafiltration of 5000-10000 again through the molecular weight that dams, 1.36 extractum when ultrafiltrate concentrating under reduced pressure relative density is 80 ℃, heating concentrates, and 30 minutes～45 minutes, extracts active component, concentrated solution is settled into pasty state, mass continues heating and is concentrated into the extractum shape, and stand for standby use becomes component 1;

As preferably, it is characterized in that among the described step c, medicinal residues add 5-10 times of water gaging and soaked 1-2 hour, extract 1 time in 1-1.5 hour, as component 2.

Adding 20-30% in the feedstuff gets final product.

Embodiment 5, prescription:

Pericarpium Granati 20g, Adeps Bovis seu Bubali 20g, Aster dubius (Thunb.) Onno 20g, Cortex Liriodendri Chinensis 20g, Radix Linderae Setchuenensis 20g, Ramulus Euonymi 15g, Herba Coriandri 15g, Folium Stenolomatis 15g, Folium Blechni orientalis 15g, Herba Centipedae 15g, Folium ailanthi 10g, Cortex Moutan 10g, Herba Menthae 10g, Rhizoma Scopoliae Japonicae 10g, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 10g, Folium Isatidis 5g, Radix berchemiae lineatae 5g, Fructus Seu Herba Pubescentis 5g, Rhizoma Zingiberis Recens 5g, Herba Capsellae 5g;

Preparation method:

By formula proportion above-mentioned Chinese medicine oven dry is ground into 300-400 purpose fine powder and uses ultrasound wave homogenize 10-30 minute under 0-10 ℃ of temperature, packing is finished product.

Can be used as feed additive and use, also can submit from fear with water 1:1.

The difference of the present invention and other drug is exactly the formulation principle by the herbal medicine monarch, the compound theory of Chinese medical science of the principles of formulating prescriptions, enlarged antibacterial range, the infectious serositis in duck invalid to general medicine still has curative effect preferably, pass through prescription, the present invention has reduced the treatment cost, has improved curative effect, can reduce chemical sproof generation simultaneously.Its preparation method is simple, and the curative effect highly significant is easy to use, applied widely.

Clinical trial:

Example 1:

Incidence: duck family Jiang is supported in Ba Bu town, Guangxi province Hezhou City, 1000 morbidities of the young duck of 20 ages in days, performance is squatted, lower limb is soft is reluctant to walk about, ataxia, cough, sneeze, dyspnea, the eye nose flows out serosity secretions, dysentery draws green or yellow green loose stool, and every day, dead 5-8 did not only wait.Householder's oxytetracycline, gentamycin sulfate are treated and DeGrain.

Diagnosis:

Get disease duckling brain, hepatic tissue and exudate smear, use the specific fluorescence antibody staining, check under fluorescence microscope, find antibacterial, antibacterial is the yellow green circulus, and mostly is the single distribution that is dispersed in, and is short chain individually and arranges.Further check and determine that this antibacterial is riemerella anatipestifer.According to the clinical onset symptom, cut open inspection pathological changes and lab testing result, be diagnosed as infectious serositis in duck.

Treatment:

Chinese medicine preparation of the present invention and water 1:1 submit from fear, and use a week continuously, and treatment back epidemic situation is controlled, cure rate 〉=88%.

Five groups of healing rates compare (example)

Claims (6)

1. Chinese medicine composition of preventing and treating infectious serositis in duck, it is characterized in that: with Pericarpium Granati, Adeps Bovis seu Bubali, Aster dubius (Thunb.) Onno, Cortex Liriodendri Chinensis, Radix Linderae Setchuenensis be that monarch drug is antibacterial, detoxifcation, antiinflammatory, be ministerial drug detoxifcation, analgesic, antiviral, adjusting gastrointestinal motility with Ramulus Euonymi, Herba Coriandri, Folium Stenolomatis, Folium Blechni orientalis, Herba Centipedae, being accessory drugs anti-stress, microcirculation improvement with Folium ailanthi, Cortex Moutan, Herba Menthae, Rhizoma Scopoliae Japonicae, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi), is adjuvant drug with Folium Isatidis, Radix berchemiae lineatae, Fructus Seu Herba Pubescentis, Rhizoma Zingiberis Recens, Herba Capsellae.

2. a kind of Chinese medicine composition of preventing and treating infectious serositis in duck according to claim 1 is characterized in that, is made up of the raw material of following weight portion:

Pericarpium Granati 15-20 part, Adeps Bovis seu Bubali 15-20 part, Aster dubius (Thunb.) Onno 15-20 part, Cortex Liriodendri Chinensis 15-20 part, Radix Linderae Setchuenensis 15-20 part, Ramulus Euonymi 10-15 part, Herba Coriandri 10-15 part, Folium Stenolomatis 10-15 part, Folium Blechni orientalis 10-15 part, Herba Centipedae 10-15 part, Folium ailanthi 5-10 part, Cortex Moutan 5-10 part, Herba Menthae 5-10 part, Rhizoma Scopoliae Japonicae 5-10 part, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 5-10 part, Folium Isatidis 1-5 part, Radix berchemiae lineatae 1-5 part, Fructus Seu Herba Pubescentis 1-5 part, Rhizoma Zingiberis Recens 1-5 part, Herba Capsellae 1-5 part;

Preparation method:

By formula proportion above-mentioned Chinese medicine oven dry is ground into 300-400 purpose fine powder and uses ultrasound wave homogenize 10-30 minute under 0-10 ℃ of temperature, packing is finished product.

3. according to any described a kind of Chinese medicine composition of preventing and treating infectious serositis in duck of claim 1-2, it is characterized in that, formed by the raw material of following weight portion:

Pericarpium Granati 16-18 part, Adeps Bovis seu Bubali 16-18 part, Aster dubius (Thunb.) Onno 16-18 part, Cortex Liriodendri Chinensis 16-18 part, Radix Linderae Setchuenensis 16-18 part, Ramulus Euonymi 11-14 part, Herba Coriandri 11-14 part, Folium Stenolomatis 11-14 part, Folium Blechni orientalis 11-14 part, Herba Centipedae 11-14 part, Folium ailanthi 6-8 part, Cortex Moutan 6-8 part, Herba Menthae 6-8 part, Rhizoma Scopoliae Japonicae 6-8 part, Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi) 6-8 part, Folium Isatidis 2-4 part, Radix berchemiae lineatae 2-4 part, Fructus Seu Herba Pubescentis 2-4 part, Rhizoma Zingiberis Recens 2-4 part, Herba Capsellae 2-4 part;

Preparation method:

A, elder generation crystallize into powder with Aster dubius (Thunb.) Onno, Adeps Bovis seu Bubali, Herba Menthae distillation;

B, get the surplus stock medicine again and put into soak with ethanol, heat is extracted 2 times, becomes the extractum shape, is component 1;

C, medicinal residues extracting in water 1 time, thickening filtration are the extractum shape, are component 2;

D, above-mentioned two kinds of extractum are condensed into pasty state, add the powder that a step obtains, add Mel and be twisted into pill.

4. a kind of Chinese medicine composition of preventing and treating infectious serositis in duck according to claim 3, it is characterized in that, among the described step b, get crude drug and add 60-90% soak with ethanol 1-2 hour that 5-10 doubly measures, heating extraction 2 times, each 1-2 hour, get supernatant, merge extractive liquid,, the 80-120 order filters, and is the ultrafiltration post ultrafiltration of 5000-10000 again through the molecular weight that dams, 1.36 extractum when ultrafiltrate concentrating under reduced pressure relative density is 80 ℃, heating concentrates, and 30 minutes～45 minutes, extracts active component, concentrated solution is settled into pasty state, mass continues heating and is concentrated into the extractum shape, and stand for standby use becomes component 1.

5. a kind of Chinese medicine composition of preventing and treating infectious serositis in duck according to claim 3 is characterized in that, among the described step c, medicinal residues add 5-10 times of water gaging and soaked 1-2 hour, extract 1 time in 1-1.5 hour, as component 2.

6. according to any described a kind of Chinese medicine composition of preventing and treating infectious serositis in duck among the claim 1-3, it is characterized in that, formed by the raw material of following weight portion:

17 parts of Pericarpium Granatis, 17 parts of Adeps Bovis seu Bubalis, 17 parts of Aster dubius (Thunb.) Onno, 17 parts of Cortex Liriodendri Chinensiss, 17 parts of Radix Linderae Setchuenensiss, 12 parts of Ramulus Euonymis, 12 parts of Herba Coriandris, 12 parts of Folium Stenolomatiss, 12 parts of Folium Blechni orientaliss, 12 parts of Herba Centipedae, 7 parts of Folium ailanthi, 7 parts of Cortex Moutans, 7 parts of Herba Menthaes, 7 parts of Rhizoma Scopoliae Japonicae, 7 parts of Ramulus et folium glochidionis eriocarpi (Folium Glochidii Eriocarpi)s, 3 parts of Folium Isatidiss, 3 parts of Radix berchemiae lineataes, 3 parts of Fructus Seu Herba Pubescentiss, 3 parts in Rhizoma Zingiberis Recens, 3 parts in Herba Capsellae.