CN103230484B - Drug for treating knee osteoarthritis of patients under age of 40 - Google Patents

Drug for treating knee osteoarthritis of patients under age of 40 Download PDF

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Publication number
CN103230484B
CN103230484B CN201310165031.8A CN201310165031A CN103230484B CN 103230484 B CN103230484 B CN 103230484B CN 201310165031 A CN201310165031 A CN 201310165031A CN 103230484 B CN103230484 B CN 103230484B
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China
Prior art keywords
grams
drug
fine powder
medicine
knee osteoarthritis
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Expired - Fee Related
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CN201310165031.8A
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Chinese (zh)
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CN103230484A (en
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贾古友
孙步伟
王月秋
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Individual
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Abstract

The invention discloses a drug for treating knee osteoarthritis of patients under the age of 40, aiming to overcome the defects of the prior art. The drug is prepared from the following components: 20g of blackberry lily rhizome, 20g of tuber fleeceflower stem, 30g of longan aril, 12g of spina date seeds, 12g of cassia twig, 12g of atractylodes rhizome, 6g of milkwort root, 18g of grassleaf sweetflag rhizome, 15g of ephedra, 10g of white mulberry root-bark and 45g of seaweed, wherein the components are uniformly mixed and ground into 180-mesh fine powder, and the fine powder is orally taken with warm boiled water twice a day, 10g each time. One course of treatment lasts three months.

Description

Treat 40 years old medicine of patient's knee joint osseous arthritis before
Technical field the invention belongs to technical field of Chinese medicines, relates to and treats 40 years old medicine of patient's knee joint osseous arthritis before, the Chinese medicine that the Chinese herbal medicine of take is specifically prepared as raw material.
Background technology knee joint osseous arthritis (knee joint OA) is common disease, and the course of disease is long, painful large, outbreak repeatedly.The cause of disease more complicated that this is sick, comprises mechanics and biochemical factors, it is generally acknowledged that pathological characteristic is that articular cartilage degeneration, erosion, destruction and hyperosteogeny form with to increase the many factors such as age, wound, endocrine, cartilage metabolism, dysimmunity and heredity relevant.The age of morbidity more and more shifts to an earlier date this disease now, a lot of patients just started morbidity at 35 years old, due to popularizing of the image technologies such as nuclear magnetic resonance, NMR, make this disease be able to early discovery, but medical circle does not but have good way to stop the irreversible pathological changes of this disease, conventional Therapeutic Method has local injection procaine and hydrocortisone acetate at present, the medicines such as oral naproxen, indometacin, but effect is not satisfactory.This serious harm patient's health, Chinese medicine is tool advantage aspect this disease for the treatment of, therefore invention treatment 40 years old before the medicine of patient's knee joint osseous arthritis treat this disease.
Summary of the invention the object of this invention is to provide treats 40 years old medicine of patient's knee joint osseous arthritis before, to overcome the deficiencies in the prior art.
The object of the invention is pathogenetic understanding and Therapeutic Principle thereof to knee joint osseous arthritis according to motherland's medical tradition medical science, with reference to modern pharmacological research, therefrom filter out natural Chinese medicinal herb, by theory of Chinese medical science prescription, it is played a role.
Medicine of the present invention is made by following component:
45 grams of 10 grams of Sargassums of 15 grams of Cortex Mori of 18 grams of Herba Ephedraes of 6 grams of Rhizoma Acori Graminei of 12 grams of Radix Polygalaes of 12 grams of Rhizoma Atractylodis of 12 grams of Ramulus Cinnamomi of 30 grams of Semen Ziziphi Spinosaes of 20 grams of Arillus Longans of 20 grams of Caulis Polygoni Multiflori of Rhizoma Belamcandae
Above-mentioned each component mix homogeneously is ground into 180 order fine powders, every day twice for oral administration, each 10 grams, warm water delivery service.It within three months, is a course for the treatment of.
Medicine of the present invention is Chinese medicine preparation, according to theory of Chinese medical science, select medicine rationally, treating both the principal and secondary aspects of a disease.Medicine of the present invention, through clinical observation patient for many years, evident in efficacy, patient's knee joint osseous arthritis patient has remarkable result before a variety of causes is caused 40 years old, has avoided further developing of conditions of patients.
Clinical drug of the present invention is taken result and is shown, has following advantage:
The present invention selects natural plant, and each component meets pharmaceutical control law regulation, utilizes the comprehensive function of each taste medicine to treat 40 years old patient's knee joint osseous arthritis before, without chemicals, nontoxic to human body, have no side effect, safe and reliable, curative effect is high, cheap, without any discomfort disease.
For showing the therapeutic effect of medicine of the present invention to 40 years old knee joint osseous arthritis before, the present invention's knee osteoarthritis patients before 540 example 40 years old carries out the clinical observation of system as test group, and select knee osteoarthritis patients 300 examples before medical history, the state of an illness, age and 40 years old suitable with traditional therapy group as a comparison, age 35-39 year, course of disease 1-4; Test group: use medicine of the present invention; Contrast groups: use routine medication.Observation period is 5 months, check after 5 months.Efficacy assessment standard adopts < < disease of tcm Standardization of diagnosis and curative effect > > in People's Republic of China's Chinese medicine industry standard in 2010.Cure: knee joint swelling, pain disappear completely, and knee joint movable function is normal.Effective: knee joint swelling disappears, and swelling pain alleviates, the overworked pain that still has, knee joint function normal.Do not heal: swelling shows effect repeatedly, the gonalgia is not alleviated.
Using method: every day twice for oral administration, each 10 grams, warm water delivery service, three months is a course for the treatment of.Clinical comparison the results are shown in Table 1.
Table 1: use medicine of the present invention and the observation of curative effect to 40 years old knee osteoarthritis patients before by conventional treatments.
Two groups of curative effect comparisons of table 1 (example, %)
Note: curative effect relatively adopts statistical method, enumeration data adopts x 2check, two groups of effective percentage compare P < 0.01
As can be seen from Table 1, two groups of effective percentage comparisons: experimental group total effective rate is 96.3%, matched group is 40.6%, experimental group is obviously better than matched group (P < 0.01), illustrates that medicine of the present invention has significance curative effect.
The specific embodiment
By following proportioning, choose raw material:
45 grams of 10 grams of Sargassums of 15 grams of Cortex Mori of 18 grams of Herba Ephedraes of 6 grams of Rhizoma Acori Graminei of 12 grams of Radix Polygalaes of 12 grams of Rhizoma Atractylodis of 12 grams of Ramulus Cinnamomi of 30 grams of Semen Ziziphi Spinosaes of 20 grams of Arillus Longans of 20 grams of Caulis Polygoni Multiflori of Rhizoma Belamcandae
Above-mentioned each component mix homogeneously is ground into 180 order fine powders, every day twice for oral administration, each 10 grams, warm water delivery service.

Claims (1)

1. treat 40 years old medicine of patient's knee joint osseous arthritis before, it is characterized in that it is the fine powder of being made by the raw material of following weight proportioning: 20 grams of Rhizoma Belamcandae, 20 grams of Caulis Polygoni Multiflori, 30 grams of Arillus Longans, 12 grams of Semen Ziziphi Spinosaes, 12 grams of Ramulus Cinnamomi, 12 grams of Rhizoma Atractylodis, 6 grams of Radix Polygalaes, 18 grams of Rhizoma Acori Graminei, 15 grams, Herba Ephedrae, 10 grams of Cortex Mori, 45 grams of Sargassums.
CN201310165031.8A 2013-04-17 2013-04-17 Drug for treating knee osteoarthritis of patients under age of 40 Expired - Fee Related CN103230484B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310165031.8A CN103230484B (en) 2013-04-17 2013-04-17 Drug for treating knee osteoarthritis of patients under age of 40

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Application Number Priority Date Filing Date Title
CN201310165031.8A CN103230484B (en) 2013-04-17 2013-04-17 Drug for treating knee osteoarthritis of patients under age of 40

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CN103230484B true CN103230484B (en) 2014-10-29

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1117390A (en) * 1994-08-25 1996-02-28 杨仁喜 Analgesic
CN102327380A (en) * 2011-10-22 2012-01-25 李进峰 Chinese medicinal composition for treating knee osteoarthritis
CN102552570A (en) * 2012-02-18 2012-07-11 孙步伟 Medicine for treating acra necrosis after bone trauma
CN103006816A (en) * 2011-09-21 2013-04-03 贾雪莲 Formula of knee joint osteoarthritis treatment traditional Chinese medicine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1117390A (en) * 1994-08-25 1996-02-28 杨仁喜 Analgesic
CN103006816A (en) * 2011-09-21 2013-04-03 贾雪莲 Formula of knee joint osteoarthritis treatment traditional Chinese medicine
CN102327380A (en) * 2011-10-22 2012-01-25 李进峰 Chinese medicinal composition for treating knee osteoarthritis
CN102552570A (en) * 2012-02-18 2012-07-11 孙步伟 Medicine for treating acra necrosis after bone trauma

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
冯新送教授从肾虚血瘀治疗骨性关节炎经验介绍;李钊;《新中医》;20111131;第43卷(第11期);第152-153页 *
刘卫.急性膝骨性关节炎的中医药治疗进展.《中国中医急症》.2011,第20卷(第02期),
急性膝骨性关节炎的中医药治疗进展;刘卫;《中国中医急症》;20110228;第20卷(第02期);第298-299页 *
李钊.冯新送教授从肾虚血瘀治疗骨性关节炎经验介绍.《新中医》.2011,第43卷(第11期),

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