CN103230484A - Drug for treating knee osteoarthritis of patients under age of 40 - Google Patents

Drug for treating knee osteoarthritis of patients under age of 40 Download PDF

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Publication number
CN103230484A
CN103230484A CN2013101650318A CN201310165031A CN103230484A CN 103230484 A CN103230484 A CN 103230484A CN 2013101650318 A CN2013101650318 A CN 2013101650318A CN 201310165031 A CN201310165031 A CN 201310165031A CN 103230484 A CN103230484 A CN 103230484A
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restrains
drug
knee joint
gram
fine powder
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CN103230484B (en
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贾古友
孙步伟
王月秋
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贾古友
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Abstract

The invention discloses a drug for treating knee osteoarthritis of patients under the age of 40, aiming to overcome the defects of the prior art. The drug is prepared from the following components: 20g of blackberry lily rhizome, 20g of tuber fleeceflower stem, 30g of longan aril, 12g of spina date seeds, 12g of cassia twig, 12g of atractylodes rhizome, 6g of milkwort root, 18g of grassleaf sweetflag rhizome, 15g of ephedra, 10g of white mulberry root-bark and 45g of seaweed, wherein the components are uniformly mixed and ground into 180-mesh fine powder, and the fine powder is orally taken with warm boiled water twice a day, 10g each time. One course of treatment lasts three months.

Description

Treat 40 years old medicine of patient's knee joint osseous arthritis before
Technical field the invention belongs to technical field of Chinese medicines, relates to treating 40 years old medicine of patient's knee joint osseous arthritis before, and be the Chinese medicine of feedstock production specifically with the Chinese herbal medicine.
Background technology knee joint osseous arthritis (knee joint OA) is common disease, and the course of disease is long, and is painful big, outbreak repeatedly.The cause of disease more complicated that this is sick comprises mechanics and biochemical factor, it is generally acknowledged with to increase multiple factors such as age, wound, endocrine, cartilage metabolism, dysimmunity and heredity relevant, and pathological characteristic is that articular cartilage degeneration, erosion, destruction and hyperosteogeny form.The age of morbidity more and more shifts to an earlier date this disease now, a lot of patients just began morbidity at 35 years old, because popularizing of image technologies such as nuclear magnetic resonance, NMR, make this disease be able to early discovery, but medical circle does not but have good way to stop the irreversible pathological changes of this disease, Therapeutic Method commonly used at present has local injection procaine and hydrocortisone acetate, medicines such as oral naproxen, indometacin, but effect is not satisfactory.This serious harm patient's health, Chinese medicine is the tool advantage aspect this disease for the treatment of, therefore invention treatment 40 years old before the medicine of patient's knee joint osseous arthritis treat this disease.
Summary of the invention the purpose of this invention is to provide treats 40 years old medicine of patient's knee joint osseous arthritis before, to overcome the deficiencies in the prior art.
The objective of the invention is with reference to modern pharmacological research, therefrom to filter out natural Chinese medicinal herb according to pathogenetic understanding and the Therapeutic Principle thereof of motherland's medical tradition medical science to knee joint osseous arthritis, by the theory of Chinese medical science prescription, it is played a role.
Medicine of the present invention is made by following component:
Rhizoma Belamcandae 20 gram Caulis Polygoni Multiflori 20 gram Arillus Longans 30 gram Semen Ziziphi Spinosaes 12 gram Ramulus Cinnamomi 12 gram Rhizoma Atractylodis 12 gram Radix Polygalaes 6 gram Rhizoma Acori Graminei 18 gram Herba Ephedraes 15 gram Cortex Mori 10 gram Sargassums 45 grams
Above-mentioned each component mix homogeneously is ground into 180 order fine powders, every day twice for oral administration, each 10 grams, warm water delivery service.Three months is a course for the treatment of.
Medicine of the present invention is Chinese medicine preparation, according to theory of Chinese medical science, select medicine rationally, treating both the principal and secondary aspects of a disease.Medicine of the present invention, evident in efficacy through clinical observation patient for many years, patient's knee joint osseous arthritis patient has remarkable result before a variety of causes is caused 40 years old, has avoided further developing of conditions of patients.
Clinical drug of the present invention is taken the result and is shown, following advantage is arranged:
The present invention selects natural plant for use, and each component meets the pharmaceutical control law regulation, utilizes the comprehensive function of the medicine of respectively distinguishing the flavor of to treat 40 years old patient's knee joint osseous arthritis before, no chemicals, nontoxic to human body, have no side effect, safe and reliable, the curative effect height, cheap, no any discomfort disease.
For showing that medicine of the present invention is to the therapeutic effect of 40 years old knee joint osseous arthritis before, the present invention knee joint osseous arthritis patient before 540 examples 40 years old carries out the clinical observation of system as test group, and select medical history, the state of an illness, knee joint osseous arthritis patient 300 examples before age and 40 years old suitable with traditional therapy to organize as a comparison, age 35-39 year, course of disease 1-4; Test group: use medicine of the present invention; Contrast groups: use routine medication.Observation period is 5 months, check after 5 months.Efficacy assessment standard adopts in People's Republic of China's Chinese medicine industry standard in 2010 " disease of tcm diagnosis criterion of therapeutical effect ".Cure: knee joint swelling, pain complete obiteration, knee joint movable function is normal.Effectively: knee joint swelling disappears, and swelling pain alleviates, the overworked pain that still has, and knee joint function is normal substantially.Do not heal: swelling shows effect repeatedly, and the gonalgia is not alleviated.
Using method: every day twice for oral administration, each 10 grams, warm water delivery service, three months is a course for the treatment of.Clinical comparison the results are shown in Table 1.
Table 1: use medicine of the present invention with the observation of curative effect of conventional treatments to the knee joint osseous arthritis patient before 40 years old.
Two groups of curative effects comparisons of table 1 (example, %)
Figure BSA00000890076900021
Annotate: curative effect relatively adopts statistical method, and enumeration data adopts x 2Check, two groups of effective percentage compare P<0.01
As can be seen from Table 1, two groups of effective percentage relatively: the experimental group total effective rate is 96.3%, and matched group is 40.6%, and experimental group obviously is better than matched group (P<0.01), illustrates that medicine of the present invention has the significance curative effect.
The specific embodiment
Choose raw material by following proportioning:
Rhizoma Belamcandae 20 gram Caulis Polygoni Multiflori 20 gram Arillus Longans 30 gram Semen Ziziphi Spinosaes 12 gram Ramulus Cinnamomi 12 gram Rhizoma Atractylodis 12 gram Radix Polygalaes 6 gram Rhizoma Acori Graminei 18 gram Herba Ephedraes 15 gram Cortex Mori 10 gram Sargassums 45 grams
Above-mentioned each component mix homogeneously is ground into 180 order fine powders, every day twice for oral administration, each 10 grams, warm water delivery service.

Claims (1)

1. treat 40 years old medicine of patient's knee joint osseous arthritis before, it is characterized in that it is the fine powder of being made by the following weight proportion raw material: Rhizoma Belamcandae 20 restrains, Caulis Polygoni Multiflori 20 restrains, Arillus Longan 30 restrains, Semen Ziziphi Spinosae 12 restrains, Ramulus Cinnamomi 12 restrains, Rhizoma Atractylodis 12 restrain, Radix Polygalae 6 restrains, Rhizoma Acori Graminei 18 restrains, Herba Ephedrae 15 restrains, Cortex Mori 10 restrains, Sargassum 45 restrains.
CN201310165031.8A 2013-04-17 2013-04-17 Drug for treating knee osteoarthritis of patients under age of 40 Expired - Fee Related CN103230484B (en)

Priority Applications (1)

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CN201310165031.8A CN103230484B (en) 2013-04-17 2013-04-17 Drug for treating knee osteoarthritis of patients under age of 40

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Application Number Priority Date Filing Date Title
CN201310165031.8A CN103230484B (en) 2013-04-17 2013-04-17 Drug for treating knee osteoarthritis of patients under age of 40

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CN103230484B CN103230484B (en) 2014-10-29

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1117390A (en) * 1994-08-25 1996-02-28 杨仁喜 Analgesic
CN102327380A (en) * 2011-10-22 2012-01-25 李进峰 Chinese medicinal composition for treating knee osteoarthritis
CN102552570A (en) * 2012-02-18 2012-07-11 孙步伟 Medicine for treating acra necrosis after bone trauma
CN103006816A (en) * 2011-09-21 2013-04-03 贾雪莲 Formula of knee joint osteoarthritis treatment traditional Chinese medicine

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1117390A (en) * 1994-08-25 1996-02-28 杨仁喜 Analgesic
CN103006816A (en) * 2011-09-21 2013-04-03 贾雪莲 Formula of knee joint osteoarthritis treatment traditional Chinese medicine
CN102327380A (en) * 2011-10-22 2012-01-25 李进峰 Chinese medicinal composition for treating knee osteoarthritis
CN102552570A (en) * 2012-02-18 2012-07-11 孙步伟 Medicine for treating acra necrosis after bone trauma

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
刘卫: "急性膝骨性关节炎的中医药治疗进展", 《中国中医急症》 *
李钊: "冯新送教授从肾虚血瘀治疗骨性关节炎经验介绍", 《新中医》 *

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