CN103223091A - 一种治疗慢性咽炎的中药组合物 - Google Patents
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Abstract
本发明公开了一种治疗慢性咽炎的中药组合物。中医认为慢性咽炎属“虚火喉痹”，多因脏腑亏损，虚火上炎所致，其病机多为风热邪毒，又感外邪，导致气机宣畅失调，郁久化火，灼伤津液，而产生一种阴虚火旺综合症状。为此，本发明选择中药小果倒地铃、金果榄、小三棵针、紫参、大黑头草、黄脚鸡、相思藤、玄参、北沙参、矮地茶、青果、雪里开、凌霄花、肿节风、黄三七，水煎成汤剂，经我院临床试验，总有效率为97.6％，明显优于对照组，值得临床推广应用。
Description
技术领域
本发明涉及一种中药组合物，尤其涉及一种治疗慢性咽炎的中药组合物。
背景技术
慢性咽炎是耳鼻咽喉科的常见病和多发病，多发于成年人，它既可以是局部病变，又可能是上呼吸道病变的一部分，临床上主要表现为咽痛、咽干、咽痒、咽异物感、刺激性干咳等，其发病的原因主要是咽部粘膜、粘膜下淋巴组织弥漫性炎症改变，其病程长、症状顽固，且不易治愈。随着人们社交活动的增多，语言交流量增大，影响人们的情绪和正常的工作生活，目前西医治疗以抗生素为主，在治疗过程中，患者由于多种原因往往不能长时间服用药品，或者由于耐药性产生，使药效减低，因此本病复发率很高，特别是慢性迁延性咽炎，西药治疗效果不理想。
发明内容
本发明的目的是提供一种治疗慢性咽炎的中药组合物。中医认为慢性咽炎属“虚火喉痹”，多因脏腑亏损，虚火上炎所致，其病机多为风热邪毒，又感外邪，导致气机宣畅失调，郁久化火，灼伤津液，而产生一种阴虚火旺综合症状。
本发明的目的是通过以下技术方案实现的，该治疗慢性咽炎的中药组合物由以下重量份的中药制成：小果倒地铃1-40份、金果榄5-15份、小三棵针6-10份、紫参7-9份、大黑头草10-15份、黄脚鸡3-25份、相思藤4-10份、玄参7-12份、北沙参10-13份、矮地茶3-25份、青果2-20份、雪里开7-10份、凌霄花6-15份、肿节风3-7份、黄三七1-4份。
优选的，小果倒地铃20份、金果榄10份、小三棵针8份、紫参8份、大黑头草13份、黄脚鸡14份、相思藤7份、玄参9份、北沙参12份、矮地茶14份、青果11份、雪里开9份、凌霄花12份、肿节风5份、黄三七3份。
制备方法将上述中药按照传统的制备方法制成汤剂。
方中：小果倒地铃、金果榄、小三棵针、紫参清热解毒，利咽止痛，活血理气；大黑头草祛风散寒，解热止痛；黄脚鸡、相思藤、玄参、北沙参养阴润肺，生津止渴，清热凉血，解毒散结，滋阴益胃；矮地茶止咳化痰，祛风解毒；青果、雪里开、凌霄花、肿节风、黄三七清热利咽，生津解毒，行气活血，抗菌消炎。
临床资料
1、一般资料所选病例均于2006年4月至2008年6月来我院就诊，并确诊为慢性咽炎的患者164例，随机分为治疗组和对照组。治疗组82例中，男50例，女32例，年龄18～40岁，平均33.5岁；对照组82例中，男45例，女37例，年龄19～45岁，平均34.8岁。两组患者病程为6个月～5年，平均病程为3年6个月。
2、诊断标准所有病例诊断参照《中药新药临床研究指导原则》，并符合诊断标准，本组慢性单纯性咽炎164例，主要为咽部不适，常感咽干、搔痒、微痛和异物感；咽反射敏感，咽后壁粘膜充血呈暗红色，有散在增生的淋巴滤泡颗粒，咽部粘膜增厚，表面小血管扩张，咽后壁淋巴滤泡增生肥大、凸起或相融成片状，咽侧索肥厚。
3、治疗方法治疗组服用本发明所述的中药组合物，即取小果倒地铃20g、金果榄10g、小三棵针8g、紫参8g、大黑头草13g、黄脚鸡14g、相思藤7g、玄参9g、北沙参12g、矮地茶14g、青果11g、雪里开9g、凌霄花12g、肿节风5g、黄三七3g，水煎成汤剂，每日一剂，分早、晚二次服用；对照组复方新诺明1.0g，每目2次，口服，华素片2片，含化，每日3次，两组均，7天为一个疗程。
4、疗效标准治愈：临床症状完全消失，咽部粘膜充血消退，咽后壁淋巴滤泡消失；显效：临床症状显著改善，咽部粘膜充血减轻，咽后壁淋巴滤泡明显减少；有效：临床症状改善，咽部粘膜充血减轻，咽后壁淋巴滤泡减少；无效：临床症状无变化。
5、治疗结果治疗组与对照组治疗两个疗程后疗效比较见表1。
表1治疗组与对照组治疗两个疗程后疗效比较
与对照组比较P＜0.05
两组比较，治疗组治愈率，总有效率，明显优于对照组，具有统计学意义。
具体实施方式
实施例一：称取小果倒地铃20g、金果榄10g、小三棵针8g、紫参8g、大黑头草13g、黄脚鸡14g、相思藤7g、玄参9g、北沙参12g、矮地茶14g、青果11g、雪里开9g、凌霄花12g、肿节风5g、黄三七3g，将上述中药按照传统的制备方法制成汤剂。
实施例二：称取小果倒地铃1g、金果榄15g、小三棵针6g、紫参9g、大黑头草15g、黄脚鸡25g、相思藤4g、玄参12g、北沙参10g、矮地茶25g、青果2g、雪里开7g、凌霄花15g、肿节风3g、黄三七1g，将上述中药按照传统的制备方法制成汤剂。
实施例三：称取小果倒地铃40g、金果榄5g、小三棵针10g、紫参7g、大黑头草10g、黄脚鸡3g、相思藤10g、玄参7g、北沙参13g、矮地茶3g、青果20g、雪里开10g、凌霄花6g、肿节风7g、黄三七4g，将上述中药按照传统的制备方法制成汤剂。
Claims (2)
1.一种治疗慢性咽炎的中药组合物，其特征在于该中药组合物由以下重量份的中药制成：小果倒地铃1-40份、金果榄5-15份、小三棵针6-10份、紫参7-9份、大黑头草10-15份、黄脚鸡3-25份、相思藤4-10份、玄参7-12份、北沙参10-13份、矮地茶3-25份、青果2-20份、雪里开7-10份、凌霄花6-15份、肿节风3-7份、黄三七1-4份。
2.根据权利要求1所述的一种治疗慢性咽炎的中药组合物，其特征在于该中药组合物由以下重量份的中药制成：小果倒地铃20份、金果榄10份、小三棵针8份、紫参8份、大黑头草13份、黄脚鸡14份、相思藤7份、玄参9份、北沙参12份、矮地茶14份、青果11份、雪里开9份、凌霄花12份、肿节风5份、黄三七3份。
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| CN1730078A (zh) * | 2005-08-09 | 2006-02-08 | 石新元 | 清咽饮茶 |
| CN101007140A (zh) * | 2007-01-25 | 2007-08-01 | 李乃元 | 一种治疗慢性咽炎的中成药 |
| CN101085228A (zh) * | 2007-06-29 | 2007-12-12 | 杨文琳 | 一种内服治疗慢性咽炎的中药组合物 |
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| CN1730078A (zh) * | 2005-08-09 | 2006-02-08 | 石新元 | 清咽饮茶 |
| CN101007140A (zh) * | 2007-01-25 | 2007-08-01 | 李乃元 | 一种治疗慢性咽炎的中成药 |
| CN101085228A (zh) * | 2007-06-29 | 2007-12-12 | 杨文琳 | 一种内服治疗慢性咽炎的中药组合物 |
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