CN103211904A - Medicament for treating hypotension - Google Patents

Abstract

The invention relates to a medicament for treating hypotension. The medicament is prepared from the following raw Chinese medicaments in parts by weight: 10 to 20 parts of codonopsis pilosula, 15 to 20 parts of roasted white atractylodes rhizome, 10 to 20 parts of astragalus root, 10 to 15 parts of Szechuan lovage rhizome, 10 to 15 parts of root of red-rooted salvia, 5 to 12 parts of rhizoma cimicifugae and 10 to 15 parts of schisandra chinensis. The raw medicaments can be prepared into tablets, pills and capsules. The medicament can improve the cardiovascular function, improve myocardial contractility, improve cardiac output and improve the arterial wall tension, so that the blood pressure is gradually raised and stabilized on normal level, and various uncomfortable symptoms caused by the hypotension are eliminated.

Description

The hypotensive medicine of a kind of treatment

Technical field

The present invention relates to a kind of medicine, it is a kind of that concrete is is that crude drug is treated hypotensive medicine with the Chinese herbal medicine.

Background technology

Hypotension refers to because blood pressure reduces a series of symptoms cause, as dizzy and faint etc.Hypotension can be divided into acute hypotension and chronic hypotension.No matter be to cause the blood pressure systolic pressure to be lower than 100mmHg owing to physiology or pathology reason, that will form hypotension.

Hypotension state of an illness light symptoms can have: dizziness, headache, inappetence, fatigue, green around the gills, dyspepsia, carsick ship etc.; Serious symptoms comprises: orthostatic is dizzy, extremity are cold, cardiopalmus, dyspnea, ataxia, pronunciation is ambiguous even faint, need long-term bed.These symptoms cause having a sluggish circulation of blood mainly because of blood pressure drops, and far-end blood capillary ischemia consequently influences the supply of histiocyte oxygen and nutrition, and the drainage of carbon dioxide and metabolic waste has especially influenced the blood supply of brain and heart.

Body function is descended greatly, and main harm comprises: vision, auditory dysesthesia, and to bring out or increase the weight of alzheimer disease, dizzy, the incidence rate of fainting, fall, fracture increases greatly.Situations such as weak, neurolysis, depressed, melancholy often take place, and have influenced patient's quality of life.

The treatment hypopiesi does not still have specific medicine, western medical treatment hypostension severe patient at present, generally all use hormone, life-time service causes serious harm to patient's body, physical exercise therapy and dietetic therapy, patient's body constitution can be improved gradually, but hypotension can not be thoroughly cured.

Summary of the invention

The purpose of this invention is to provide the hypotensive medicine of a kind of treatment, can improve cardiovascular function, increase myocardial contraction, increase cardiac output, improve the ductus arteriosus wall tensity, thereby progressively make increased blood pressure and stablize normal level, eliminate all malaise symptoms that hypotension is brought.

Medicine of the present invention is that crude drug prepares by following parts by weight of traditional Chinese medicines:

Radix Codonopsis 10-20 Rhizoma Atractylodis Macrocephalae (parched) 15-20 Radix Astragali 10-20

Rhizoma Chuanxiong 10-15 Radix Salviae Miltiorrhizae 10-15 Rhizoma Cimicifugae 5-12

Fructus Schisandrae Chinensis 10-15.

Said medicine can be made any dosage form on the pharmaceutics, as tablet, pill, powder, capsule etc., the preferred dosage form of the present invention is a powder.

The concrete preparation method of powder of the present invention:

Said medicine by described parts by weight mix homogeneously, is ground into 120～135 purpose medicated powder, and sterilization makes the powder product.

The traditional Chinese medical science thinks that hypotension is a heart deficiency of spleen-YANG, YANG QI deficiency, blood capable weak due to, pay attention to warming the spleen kidney yang invigorating gas in the treatment, Radix Codonopsis spleen invigorating lung benefiting in this prescription, nourishing blood to promote the production of body fluid; The Rhizoma Atractylodis Macrocephalae (parched) invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis; Radix Astragali tonifying Qi and lifting yang, strengthening superficial resistance to stop perspiration, inducing diuresis to remove edema promotes the production of body fluid and nourishes blood; The Rhizoma Chuanxiong blood-activating and qi-promoting, wind-expelling pain-stopping; The Radix Salviae Miltiorrhizae blood circulation promoting and blood stasis dispelling, inducing menstruation to relieve menalgia, relieving restlessness clears away heart-fire; Rhizoma Cimicifugae is delivered rash, heat-clearing and toxic substances removing, elevate a turnable ladder yang-energy; The Fructus Schisandrae Chinensis convergence is astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming; All medicines share the spleen invigorating yang invigorating, the QI invigorating that nourishes blood, and the kidney invigorating is promoted the production of body fluid.

For further investigating the clinical efficacy and the safety of medicine of the present invention, select 121 routine hypotensives that the curative effect of medicine of the present invention has been carried out clinical observation.

121 routine cases are divided into two groups at random, and 63 examples are organized in treatment, matched group 58 examples.All case all meets hypotension routine diagnosis standard: blood pressure is lower than 100/60mmHg (13.33/8 kPa), particularly pulse pressure difference below 20mmHg (2.67 kPa).

Therapeutic Method

Matched group adopts ginseng stilbene Li Dekang sheet, and is oral, one time 4～6,2 times on the one.The treatment group adopts powder agent medicine of the present invention to treat, every day 3 times, each 6 grams.15 days is a course of treatment, uses 2 courses of treatment altogether.

Criterion of therapeutical effect

With reference to hypotensive criterion of therapeutical effect in " traditional Chinese medical science disease diagnosis criterion of therapeutical effect " of State Administration of Traditional Chinese Medicine's formulation.

Clinic control: treatment back blood pressure recovers normal, systolic pressure rising 〉=20mmHg, diastolic pressure rising 〉=10mmHg.

Produce effects: treatment back blood pressure recovers normally substantially, systolic pressure rising＜20 mmHg, 〉=10mmHg; Diastolic pressure＜10 mmHg, 〉=5mmHg.

Effectively: treatment back blood pressure changes before the treatment, but does not recover normal, systolic pressure rising＞5mmHg,＜10mmHg; Diastolic pressure rising＞3 mmHg,＜5mmHg.

Invalid: blood pressure does not have change before and after the treatment.

Therapeutic outcome

63 routine patient's clinic control 32 examples, control rate 50.8% are organized in treatment; Produce effects 23 examples, obvious effective rate 36.5%; Effective 3 examples, effective percentage 4.8%; Invalid 5 examples, inefficiency 7.9%; Total effective rate is 92.1%; Matched group 58 routine patient's clinic control 25 examples, control rate 43.1%; Produce effects 18 examples, obvious effective rate 31.0%; Effective 6 examples, effective percentage 10.3%; Invalid 9 examples, inefficiency 15.6%; Total effective rate is 84.4%.

The specific embodiment

Embodiment 1

Get Radix Codonopsis 100g, Rhizoma Atractylodis Macrocephalae (parched) 75 g, the Radix Astragali 50 g, Rhizoma Chuanxiong 60 g, Radix Salviae Miltiorrhizae 63 g, Rhizoma Cimicifugae 35 g, Fructus Schisandrae Chinensis 65 g;

Said medicine by described parts by weight mix homogeneously, is ground into 120～135 purpose medicated powder, and sterilization makes powder.

Embodiment 2

Radix Codonopsis 10-20 Rhizoma Atractylodis Macrocephalae (parched) 15-20 Radix Astragali 10-20

Rhizoma Chuanxiong 10-15 Radix Salviae Miltiorrhizae 10-15 Rhizoma Cimicifugae 5-12

Fructus Schisandrae Chinensis 10-15.

Get Radix Codonopsis 200g, Rhizoma Atractylodis Macrocephalae (parched) 150 g, the Radix Astragali 180 g, Rhizoma Chuanxiong 150g, Radix Salviae Miltiorrhizae 130 g, Rhizoma Cimicifugae 90 g, Fructus Schisandrae Chinensis 140g;

Said medicine by described parts by weight mix homogeneously, is ground into 120～135 purpose medicated powder, and sterilization makes powder.

Claims (2)

1. treating hypotensive medicine for one kind, is that crude drug prepares by following parts by weight of traditional Chinese medicines:

Radix Codonopsis 10-20 Rhizoma Atractylodis Macrocephalae (parched) 15-20 Radix Astragali 10-20

Rhizoma Chuanxiong 10-15 Radix Salviae Miltiorrhizae 10-15 Rhizoma Cimicifugae 5-12

Fructus Schisandrae Chinensis 10-15.

2. the hypotensive medicine of the described treatment of claim 1, its preparation method is as follows:

Said medicine by described parts by weight mix homogeneously, is ground into 120～135 purpose medicated powder, and sterilization makes powder.