CN103211891B - Externally-applied Chinese medicinal preparation for treating bone traumatic osteomyelitis - Google Patents
Externally-applied Chinese medicinal preparation for treating bone traumatic osteomyelitis Download PDFInfo
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- CN103211891B CN103211891B CN201310164348.XA CN201310164348A CN103211891B CN 103211891 B CN103211891 B CN 103211891B CN 201310164348 A CN201310164348 A CN 201310164348A CN 103211891 B CN103211891 B CN 103211891B
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Abstract
The invention discloses an externally-applied Chinese medicinal preparation for treating bone traumatic osteomyelitis. The bone traumatic osteomyelitis belongs to the suppurative osteomyelitis range of traditional Chinese medicine and is caused by infection of bones (marrow, sclerotin and periosteum) and surrounding soft tissues after the pathogenic bacteria invade the bones; and the main symptom of the bone traumatic osteomyelitis causes heavy heat and pain on the infected parts and belongs to the symptom of congested heat toxin in the traditional Chinese medicine. Therefore, the externally-applied Chinese medicinal preparation is prepared by taking Chinese medicaments comprising jasminum laurifolium, nauclea, the root of Chinese pulsatilla, pyrolusite, tree falsespiraea bark, raphiolepis indica, rhizoma panacis majoris and herb of glabrous sarcandra as the raw materials, then commonly grinding the raw materials into powder, and sieving with a sieve of 100 meshes. The Chinese medicinal preparation is mixed with egg oil and externally applied to the infected parts. By clinical experiments, various indexes alleviating conditions are better than the control group, so that the Chinese medicinal preparation is worthy of clinical popularization and application.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to one and treat the myelitic Traditional Chinese Medicine for external application preparation of bone wound.
background technology
One of modal reason of Traumatic osteomyelitis is the postoperative infection of open fracture, secondly for occurring infecting after fracture open reduction or the operation of other osteoarthrosis.Can be acutely or chronic, pathological changes is all near fracture end.The infection of acute stage is the most serious to infect in pulp cavity, and patient has the toxemia synptoms such as high heat, shiver with cold, similar to acute hematogenous osteomyelitis.Another kind of former because near skin fracture.Muscular death infects, and the fracture segment that makes to lose blood supply is exposed in air and dry downright bad, and it is chronic that the course of disease proceeds to, damaged with Infected nonunion or bone toward contact.Traumatic osteomyelitis causes great misery to patient, doctor trained in Western medicine is at the heavy dose of application-aware antibiotic of the many employings of clinical treatment primary disease at present, row focal cleaning after acute stage symptom control, the radical cure of Jia Bishi lavation art, but because early symptom is easy to obscure mutually with the disease such as postoperative infection, soft tissue purulent infection of fracturing, easily cause to lose and control or wrong treatment, and formation chronic osteomyelitis, and the easy drug resistance of primary disease pathogenic bacterium, causes clinical symptoms wayward, nursing problem is difficult for solving.
summary of the invention
The object of this invention is to provide one and treat the myelitic Traditional Chinese Medicine for external application preparation of bone wound.Bone wound osteomyelitis belongs to motherland's medical science " pyogenic infection of the bone " category, because pathogenic bacterium are invaded bone, causes bone (bone marrow, sclerotin, periosteum) and surrounding soft tissue thereof to infect and causes, and main manifestations is affected part red and swollen heat pain weight, belongs to the card of traditional Chinese medical science hyperactivity of toxic heat.
The object of the invention is to be achieved through the following technical solutions, the myelitic Traditional Chinese Medicine for external application preparation of this treatment bone wound is made up of the Chinese medicine of following weight portion: Herba Jasmini laurifolii 5-15 part, Lignum et Radix Naucleae 3-10 part, Radix Pulsatillae 6-9 part, pyrolusitum 7-11 part, Cortex Sorbariae Arboreae 3-7 part, Ramulus et Folium Raphiolepis indicae 6-20 part, Rhizoma Panacis Majoris 4-8 part, Herba Sarcandrae 8-13 part.
Preferably, 10 parts of Herba Jasmini laurifoliis, 7 parts of Lignum et Radix Naucleae, 7 parts of the Radix Pulsatillaes, 9 parts of pyrolusitums, 5 parts of Cortex Sorbariae Arboreaes, 13 parts of Ramulus et Folium Raphiolepis indicaes, 6 parts of Rhizoma Panacis Majoris, 11 parts of Herba Sarcandraes.
Above-mentioned Chinese medicine is ground into end by preparation method, crosses 100 mesh sieves, for subsequent use with egg oil mediation.
Fang Zhong: Herba Jasmini laurifolii, Lignum et Radix Naucleae, Radix Pulsatillae heat-clearing and toxic substances removing, antiinflammatory diuresis, reducing swelling and alleviating pain, removing heat from blood; Pyrolusitum, Cortex Sorbariae Arboreae promoting blood circulation to remove blood stasis, detumescence and promoting granulation, pain relieving; Ramulus et Folium Raphiolepis indicae, Rhizoma Panacis Majoris antiinflammatory removing the necrotic tissue, hemostasia and promoting granulation; Herba Sarcandrae anti-inflammation, blood circulation promoting and dispersing pathogen accumulation.
Clinical data
1, the selected case of physical data is the court's inpatient, and menses routine test and X-ray or CT sheet check, be diagnosed as the myelitic patient of bone wound.Inclusive criteria: get rid of canceration possibility, without serious internal medicine illness, the course of disease does not exceed 1 year person, is divided at random two groups, treatment group 35 examples, male's 25 examples, women's 10 examples; 15～70 years old age; The course of disease 8～315d; Diseased region is in tibia person 16 examples, and femur 5 examples, point 4 examples, toes 3 examples, calcaneus 3 examples, metacarpal bone 2 examples, humerus 1 example, radius 1 example.Matched group 35 examples, male's 23 examples, women's 12 examples; 16～75 years old age; The course of disease 9～320d; Diseased region is in tibia person 15 examples, and femur 6 examples, point 4 examples, toes 4 examples, calcaneus 3 examples, metacarpal bone 2 examples, humerus 1 example.The no significant differences such as two groups of patient ages, sex, diseased region and scopes, the course of disease; P < 0.05, has comparability.
2, criterion of therapeutical effect (1) swelling value is that perimeter value is the most seriously located in the swelling of human health screening suffering limb, subtracts strong side corresponding position perimeter value, gets the average of 3 measured values.Suffering limb detumescence >=3mm after Herbal medicines for external use, for effectively; Because of the two limb thicknesses of healthy human body incomplete same, while differing 1mm, can ignore.(2) pain calibration is given an oral account words point system according to surgery, and painless is 0 point; [pain can be born 1 point to mild pain; Moderate pain (application analgesic after pain relief)] 2 points.3 points of severe pain (sharp ache, substantially invalid after application analgesic).(3) transference cure: local red and swollen heat pain disappears, body temperature normal range continuous 3d or more than, blood routine examination numeration of leukocyte is 4 × 10
9～10 × 10
9between/L.
3, Therapeutic Method treatment group external application Traditional Chinese Medicine for external application preparation of the present invention, after postoperative each aseptic changing dressings, on former nursing basis, antibiotic Local treatment, wound Traditional Chinese Medicine for external application preparation; Medicine mud is evenly applied to the thick approximately 2～3mm in affected part red and swollen heat pain place, notes avoiding burst pus and skin lesion place, covered with plastic film on medicine mud, and the mud of more changing dressings in time, to keep a medicine muddy water point abundance to be beneficial to skin permeation; Matched group: give the medicine such as sensitive antibiotic, analgesic anti-inflammatory, repercussive and analgesic after clarifying a diagnosis, after acute stage symptom disappears, row focal cleaning, adds the radical cure of Closed irrigation art.
4, (1) two group of acute stage symptom disappearance situation of therapeutic outcome and treat that the art time is relatively in table 1.
Table 1 liang is organized acute stage symptom disappearance situation and treats the comparison of art time
With matched group comparison, P < 0.01,
Result shows from medicine effective time, and transference cure situation is treated the aspect comparison of art time, and treatment group is obviously better than matched group (P < 0.01).
After (2) two groups of Herbal medicines for external uses, partial gall disappearance situation is relatively in table 2.
Partial gall disappearance situation comparison after table 2 liang group Herbal medicines for external use
With matched group comparison, P < 0.01
Two groups of comparison treatment groups are better than matched group.
Detailed description of the invention
Embodiment mono-: take Herba Jasmini laurifolii 10g, Lignum et Radix Naucleae 3g, Radix Pulsatillae 7g, pyrolusitum 9g, Cortex Sorbariae Arboreae 5g, Ramulus et Folium Raphiolepis indicae 13g, Rhizoma Panacis Majoris 6g, Herba Sarcandrae 11g, above-mentioned Chinese medicine is ground into end, cross 100 mesh sieves, for subsequent use with egg oil mediation.
Embodiment bis-: take Herba Jasmini laurifolii 15g, Lignum et Radix Naucleae 3g, Radix Pulsatillae 6g, pyrolusitum 11g, Cortex Sorbariae Arboreae 3g, Ramulus et Folium Raphiolepis indicae 20g, Rhizoma Panacis Majoris 4g, Herba Sarcandrae 8g, above-mentioned Chinese medicine is ground into end, cross 100 mesh sieves, for subsequent use with egg oil mediation.
Embodiment tri-: take Herba Jasmini laurifolii 5g, Lignum et Radix Naucleae 10g, Radix Pulsatillae 9g, pyrolusitum 7g, Cortex Sorbariae Arboreae 7g, Ramulus et Folium Raphiolepis indicae 6g, Rhizoma Panacis Majoris 8g, Herba Sarcandrae 13g, above-mentioned Chinese medicine is ground into end, cross 100 mesh sieves, for subsequent use with egg oil mediation.
Claims (2)
1. a treatment bone wound myelitic Traditional Chinese Medicine for external application preparation, is characterized in that this Traditional Chinese Medicine for external application preparation is made up of the Chinese medicine of following weight portion: Herba Jasmini laurifolii 5-15 part, Lignum et Radix Naucleae 3-10 part, Radix Pulsatillae 6-9 part, pyrolusitum 7-11 part, Cortex Sorbariae Arboreae 3-7 part, Ramulus et Folium Raphiolepis indicae 6-20 part, Rhizoma Panacis Majoris 4-8 part, Herba Sarcandrae 8-13 part.
2. one according to claim 1 is treated the myelitic Traditional Chinese Medicine for external application preparation of bone wound, it is characterized in that this Traditional Chinese Medicine for external application preparation is made up of the Chinese medicine of following weight portion: 10 parts of Herba Jasmini laurifoliis, 7 parts of Lignum et Radix Naucleae, 7 parts of the Radix Pulsatillaes, 9 parts of pyrolusitums, 5 parts of Cortex Sorbariae Arboreaes, 13 parts of Ramulus et Folium Raphiolepis indicaes, 6 parts of Rhizoma Panacis Majoris, 11 parts of Herba Sarcandraes.
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| CN105362440A (en) * | 2015-12-10 | 2016-03-02 | 隋妍蕾 | Chinese and Western medicine compound composition for treating scalp infection and preparation method of composition |
| CN112089771A (en) * | 2020-07-31 | 2020-12-18 | 黄凯 | Method for treating traumatic osteomyelitis |
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| CN1268359C (en) * | 2003-07-02 | 2006-08-09 | 徐湘 | Medicine for treating osteomyelitis and its preparing method |
| CN101269173A (en) * | 2008-05-15 | 2008-09-24 | 天科仁祥技术（北京）有限责任公司 | Chinese medicinal composition for treating osteomyelitis and preparation method thereof |
| CN102000302B (en) * | 2010-11-18 | 2012-05-30 | 吴兴保 | Swelling-dispersing pain-relieving ointment for rheumatism and traumatic injury and preparation method thereof |
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