CN103200951A - 来自灯心草棒尾蝎毒液的肽以及药物组合物 - Google Patents

来自灯心草棒尾蝎毒液的肽以及药物组合物 Download PDF

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Publication number
CN103200951A
CN103200951A CN2011800541685A CN201180054168A CN103200951A CN 103200951 A CN103200951 A CN 103200951A CN 2011800541685 A CN2011800541685 A CN 2011800541685A CN 201180054168 A CN201180054168 A CN 201180054168A CN 103200951 A CN103200951 A CN 103200951A
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CN
China
Prior art keywords
scorpion
venom
rjlb
peptide
molecular weight
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Pending
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CN2011800541685A
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English (en)
Chinese (zh)
Inventor
J·A·弗拉加卡斯特罗
R·M·梅迪纳加利
A·迪亚斯加西亚
I·盖瓦拉欧雷亚内斯
C·C·罗德里盖斯托雷斯
J·罗德里盖斯寇佩尔
Y·里盖内斯加罗伯
I·冈萨雷斯马雷诺
M·R·佩雷斯卡波带
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GRUPO EMPRESARIAL DE PRODUCCIONES BIOFARMACEUTICAS Y QUIMICAS
Original Assignee
GRUPO EMPRESARIAL DE PRODUCCIONES BIOFARMACEUTICAS Y QUIMICAS
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Publication of CN103200951A publication Critical patent/CN103200951A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1767—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43513—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae
    • C07K14/43522—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from arachnidae from scorpions

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Insects & Arthropods (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN2011800541685A 2010-09-27 2011-09-27 来自灯心草棒尾蝎毒液的肽以及药物组合物 Pending CN103200951A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CU2010000186A CU24055B1 (es) 2010-09-27 2010-09-27 Composiciones farmacéuticas de veneno de escorpión rhopalurus junceus
CU2010-0186 2010-09-27
PCT/CU2011/000006 WO2012041261A2 (es) 2010-09-27 2011-09-27 Peptidos del veneno de escorpion rhopalorus junceus y composicion farmaceutica

Publications (1)

Publication Number Publication Date
CN103200951A true CN103200951A (zh) 2013-07-10

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CN2011800541685A Pending CN103200951A (zh) 2010-09-27 2011-09-27 来自灯心草棒尾蝎毒液的肽以及药物组合物

Country Status (17)

Country Link
EP (1) EP2623111A2 (enExample)
JP (1) JP2013542196A (enExample)
KR (1) KR20140041381A (enExample)
CN (1) CN103200951A (enExample)
AP (1) AP2013006811A0 (enExample)
AR (1) AR083117A1 (enExample)
AU (1) AU2011307691A1 (enExample)
BR (1) BR112013007198A2 (enExample)
CA (1) CA2812841A1 (enExample)
CO (1) CO6781464A2 (enExample)
CU (1) CU24055B1 (enExample)
EC (1) ECSP13012595A (enExample)
IL (1) IL225577A0 (enExample)
MX (1) MX360726B (enExample)
RU (1) RU2563348C2 (enExample)
SG (1) SG191708A1 (enExample)
WO (1) WO2012041261A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103074304B (zh) * 2013-01-28 2016-01-13 江苏健安生物科技有限公司 高水平人二倍体细胞培养水痘-带状疱疹疫苗病毒方法
MX2019000570A (es) * 2018-12-19 2020-08-13 Centro De Investig Biologicas Del Noroeste S C Composición homeopatica a base de veneno de escorpión rhopalurus junceus y su uso en acuicultura.
EP4267251A4 (en) * 2020-12-22 2024-12-18 Preveceutical Medical Inc. CYCLIC PEPTIDES AND USES THEREOF
CN113384682B (zh) * 2021-05-31 2023-07-04 南方医科大学 蝎毒多肽Smp43在制备抗肿瘤药物的应用
CN117069800B (zh) * 2023-10-16 2023-12-12 山东省食品药品检验研究院 一种鉴别东亚钳蝎的特征多肽及其应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1341662A (zh) * 2001-09-30 2002-03-27 沈阳药科大学 蝎镇痛抗肿瘤缬精甘肽及获得方法
CN1373219A (zh) * 2002-01-18 2002-10-09 中国科学院上海有机化学研究所 重组东亚马氏钳蝎毒rBmKaIT1的基因工程
US20090123558A1 (en) * 2007-11-13 2009-05-14 Arthur Mikaelian Polarized Scorpion Venom Solution and a Method for Making Polarized Scorpion Venom Solution

Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
CN1030229C (zh) 1991-12-16 1995-11-08 山东省蒙阴县酒厂 全蝎酒的制作方法
CN1076858A (zh) 1993-03-24 1993-10-06 王强华 熊胆全蝎酒及其制备工艺
CU22413A1 (es) 1994-01-11 1996-01-31 Composicion antitumoral
US5905027A (en) 1995-12-27 1999-05-18 Uab Research Foundation Method of diagnosing and treating gliomas
FR2745004B1 (fr) * 1996-02-16 1998-03-27 Rhone Poulenc Agrochimie Peptide antibacterien et antifongique
US6168651B1 (en) 1998-10-08 2001-01-02 Donaldson Company, Inc. Filter assembly with shaped adsorbent article; and devices and methods of use
CN1279088A (zh) 1999-06-25 2001-01-10 谷令旗 一种治疗肝癌药剂的制备方法
CN1265901A (zh) 2000-01-26 2000-09-13 徐忠廷 一种抗癌中药丸剂
CN1316249A (zh) 2001-04-04 2001-10-10 李滋星 全蝎活性营养液
CN1157215C (zh) 2001-07-30 2004-07-14 张官锁 一种治疗癌症的中药组合物
MXPA04011871A (es) * 2002-05-31 2005-07-26 Transmolecular Inc Quimioterapia en combinacion con clorotoxina.
CN1256971C (zh) 2002-08-12 2006-05-24 徐继康 一种用于治疗肿瘤的中药胶囊

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1341662A (zh) * 2001-09-30 2002-03-27 沈阳药科大学 蝎镇痛抗肿瘤缬精甘肽及获得方法
CN1373219A (zh) * 2002-01-18 2002-10-09 中国科学院上海有机化学研究所 重组东亚马氏钳蝎毒rBmKaIT1的基因工程
US20090123558A1 (en) * 2007-11-13 2009-05-14 Arthur Mikaelian Polarized Scorpion Venom Solution and a Method for Making Polarized Scorpion Venom Solution

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
孔天翰 等: "7 种蝎毒的高效液相分析及毒理学研究", 《河南医科大学学报》, vol. 34, no. 1, 31 March 1999 (1999-03-31), pages 63 - 66 *

Also Published As

Publication number Publication date
AP2013006811A0 (en) 2013-04-30
CU24055B1 (es) 2014-12-26
AU2011307691A1 (en) 2013-05-02
CA2812841A1 (en) 2012-04-05
WO2012041261A3 (es) 2012-11-22
ECSP13012595A (es) 2014-11-28
RU2013119431A (ru) 2014-11-10
KR20140041381A (ko) 2014-04-04
BR112013007198A2 (pt) 2016-06-14
SG191708A1 (en) 2013-08-30
CU20100186A7 (es) 2012-06-21
AR083117A1 (es) 2013-01-30
IL225577A0 (en) 2013-06-27
CO6781464A2 (es) 2013-10-31
MX360726B (es) 2018-11-13
WO2012041261A2 (es) 2012-04-05
RU2563348C2 (ru) 2015-09-20
MX2013003545A (es) 2013-11-04
JP2013542196A (ja) 2013-11-21
EP2623111A2 (en) 2013-08-07

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