CN103191384A - Medicament for treating talalgia and preparation method thereof - Google Patents

Abstract

The invention discloses a medicament for treating talalgia and a preparation method thereof. The medicament is mainly prepared from rhubarb, achyranthes root, clubmoss herb, suberect spatholobus stem, bark of himalayan coralbean, glossy privet fruit, aconite and the like in a certain weight ratio. The medicament has the functions of diminishing inflammation, relieving pain, promoting blood circulation to remove blood stasis, stimulating menstrual flow, fixing channels, inducing resuscitation and chilling bones, and is quick in response for treating the talalgia, good in treatment effect and high in cure rate.

Description

A kind of medicine for the treatment of talalgia and preparation method thereof

Technical field

The present invention relates to a kind of medicine for the treatment of talalgia and preparation method thereof, belong to the field of Chinese medicines.

Technical background

Talalgia is heel one or both sides pain, not red pneumonedema, and walking disorder claims the heel pain again.Be because the sclerotin of heel, joint, synovial bursa, fascia etc. are located the disease that pathological changes causes.Common is plantar fasciitis, often occur in standing for a long time or walking worker, long-term, chronic slight wound causes, shows as sole of the foot fascia fibrous fracture and repair process, inboard partially fascia hyperosteogeny and tenderness nearby below calcaneus, side position X actinogram shows calcanean spur.The talalgia The Long-term Effect patient's daily life and work, at present, because Western medicine can't effectively be treated talalgia, and recurrence easily, and more side effect is arranged, therefore, there is very big demand in people to the Chinese medicine of effective treatment talalgia.

Summary of the invention

The inventor has found the medicine of effective treatment talalgia finally, thereby has finished the present invention according to the research of theory of Chinese medical science and clinical repeatedly test and checking.

Purpose of the present invention just provides a kind of composition of medicine that can effectively treat talalgia.

Another object of the present invention has just provided the preparation method of this composition of medicine.

Medicine of the present invention selects Radix Et Rhizoma Rhei, Radix Achyranthis Bidentatae, Herba Lycopodii, Rhizoma Drynariae, Radix Solani Melongenae, Rhizoma Zingiberis Recens, Caulis Spatholobi, Rhizoma Paridis, Radix Gentianae Macrophyllae, Cortex erythrinae, Fructus Ligustri Lucidi, Folium Salicis Babylonicae, Radix Angelicae Pubescentis, Fructus Tribuli, Spina Gleditsiae, Radix Aconiti Kusnezoffii, Fructus Anisi Stellati, Flos Carthami, Retinervus Luffae Fructus, Fructus Chaenomelis, Myrrha medicine to make up, make each efficacy of drugs produce synergism these drug regimens, thereby can effectively treat the recurrence of talalgia.Wherein select for use Radix Et Rhizoma Rhei to be because its nature and flavor hardship, cold is gone into stomach, large intestine, liver footpath, the poison of purging heat is arranged, removing mass stagnates, the function of clots absorbing blood is controlled the excess-heat constipation, and delirium is gone mad, the food stagnation feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menolipsis Bi ， lumps in the chest and abdomen, the time row epidemic disease due to heat pathogen, sudden and violent swelling ophthalmalgia is spitted blood epistaxis, YANG jaundice, edema, stranguria with turbid discharge, it is red to urinate, the carbuncle and ulcer toxic swelling, furuncle, burn.Select for use Radix Achyranthis Bidentatae to be because its nature and flavor sweetness and bitterness acid is flat, go into liver, kidney channel, give birth to and use dissipating blood stasis blood, the function of subduing inflammation is controlled gonorrhea, hematuria, amenorrhea ， mass in the abdomen, difficult labour, retention of placenta, postnatal blood stasis stomachache, sore throat, carbuncle, traumatic injury is ripely used invigorating the liver and kidney, and bone and muscle strengthening is controlled waist kneecap pain, spasm of the limbs, flaccidity syndrome and arthralgia syndrome.Selecting Herba Lycopodii for use is that temperature is gone into liver, stomach, kidney three warps, and expelling wind and cold is arranged because of its nature and flavor toil, the dehumidifying detumescence, and the function of relaxing muscles and tendons to promote blood circulation is controlled anemofrigid-damp arthralgia, joint aches, skin numbness, tetraparesis, edema, traumatic injury.Selecting Rhizoma Drynariae for use is that temperature is gone into liver, kidney channel, and the kidney invigorating is arranged, and invigorates blood circulation because of its nature and flavor hardship, and the function of hemostasis is controlled suffer from a deficiency of the kidney chronic diarrhea and lumbago, rheumatic arthralgia, toothache, tinnitus, traumatic injury sprain and contusion, bone injury, appendicitis, alopecia areata, clavus.Select for use Radix Solani Melongenae to be because the sweet suffering of its nature and flavor is cold, control chronic dysentery and have blood in stool, beriberi, toothache, chilblain.Selecting Rhizoma Zingiberis Recens for use is because its nature and flavor suffering, and temperature is gone into lung, stomach, spleen channel, deliver, and cold expelling, preventing or arresting vomiting is opened the function of expectorant, the wind and cold that cures cold, vomiting, phlegm retention is breathed with cough, and distension is had loose bowels, and separates the Rhizoma Pinelliae, Rhizoma Arisaematis and fish Eriocheir sinensis, birds and beasts meat poison.Selecting Caulis Spatholobi for use is because its property bitter but sweet flavor, and temperature is gone into the heart, spleen two warps, have invigorate blood circulation, the function of Shujin, control soreness of waist and knee joint, paralysis and numbness, menoxenia.Select for use Rhizoma Paridis to be because its nature and flavor hardship is slightly cold, slightly poisonous, return Liver Channel, heat-clearing and toxic substances removing is arranged, reducing swelling and alleviating pain, the function of cool liver arresting convulsion is controlled the furuncle carbuncle, laryngopharynx swelling and pain, venom falls and pounces on the pain of injury, convulsion with spasms.Select for use Radix Gentianae Macrophyllae to be because its nature and flavor toil is flat, go into liver, stomach, gallbladder meridian, expelling wind and removing dampness and blood Shujin are arranged, the function of clearing away heat and promoting diuresis, the dispelling the wind and dampness pathogens arthralgia pain, the muscles and bones contracture, jaundice is had blood in stool, osteopyrexia and fever, children's's infantile malnutrition with fever, dysuria.Select for use Cortex erythrinae to be because its nature and flavor toil is flat, go into liver, spleen channel, wind-damp dispelling is arranged, the meridian dredging, the function of parasite killing, dispelling the wind and dampness pathogens arthralgia pain, dysentery, toothache, scabies.Select for use Fructus Ligustri Lucidi to be because its property bitter but sweet flavor is flat, go into liver, kidney channel, invigorating the liver and kidney is arranged, the function of strong waist knee joint is controlled yin asthenia generating intrinsic heat, dizziness, order flower tinnitus, soreness of the waist and knees, early whitening of beard and hair.Select for use Folium Salicis Babylonicae to be because its nature and flavor hardship is cold, nontoxic, go into the heart, spleen two warps, heat clearing away is arranged, rash, diuresis, the function of detoxifcation, it is not smooth to control saturating of acute diseases such as cholera and sunstroke rash, nebulousurine, the furuncle furuncle and phyma, mastitis, goiter, erysipelas is scalded, toothache.Select for use Radix Angelicae Pubescentis to be because its nature and flavor are arduous, temperature is gone into kidney, urinary bladder channel, dispels the wind, and win and wet, cold expelling, the function of pain relieving is controlled anemofrigid-damp arthralgia, waist urushic acid pain, trick spasm and pain, chronic tracheitis, headache, toothache.Selecting Fructus Tribuli for use is because its nature and flavor toil, and temperature is gone into liver, lung meridian, and diffusing wind is arranged, make eye bright, and the therapeutic method to keep the adverse QI flowing downwards, the function of promoting the circulation of blood is controlled headache, itching over the body, the conjunctival congestion nebula that swell, fullness in the chest, cough with dyspnea ， mass in the abdomen, breast difficulty, carbuncle, scrofula.Selecting Spina Gleditsiae for use is that temperature is searched wind because of its nature and flavor suffering, draw out pus by applying a plaster to the affected part, and detumescence, the function of evacuation of pus is controlled carbuncle, sore, leprosy, tinea skin ulcer, placenta retention.Select Radix Aconiti Kusnezoffii for use, the different name Radix Aconiti Kusnezoffii, its nature and flavor suffering, heat, poisonous, go into liver, spleen, lung meridian, search wind prevailing over dampness, dispersing cold for relieving pain, open expectorant, the function of detumescence is controlled anemofrigid-damp arthralgia, paralysis due to windstroke, tetanus, wind syndrome of head, coldness and pain in the epigastrium, accumulation of phlegm in the hypochondrium, air parcel, cold-dysentery, sore throat, carbuncle, furuncle, scrofula.Select Fructus Anisi Stellati for use, claim Fructus Anisi Stellati again, its property acrid-sweet flavor, temperature has warming YANG, cold expelling, the function of regulating the flow of vital energy is controlled the invasion by pathogenic cold vomiting, colic of cold type stomachache, lumbago due to renal deficiency, dried beriberi caused by pathogenic damp.Selecting Flos Carthami for use is that temperature is gone into the heart, Liver Channel, and promoting blood circulation to restore menstrual flow is arranged because of its nature and flavor suffering, and the function of blood stasis removing pain relieving is controlled amenorrhea ， mass in the abdomen, difficult labour, and stillborn fetus, disease that postpartum lochia can't go, blood stasis is had a pain, carbuncle, injury from falling down.Select for use Retinervus Luffae Fructus to be because its nature and flavor are sweet, flat, dredge the meridian passage is arranged, the function of removing heat-phlegm is controlled pain in chest and hypochondrium, stomachache, lumbago, painful and swollen testis, lung-heat productive cough, women's amenorrhea, galactostasis, carbuncle, anal fistula.Selecting Fructus Chaenomelis for use is that temperature is gone into liver, spleen channel, and suppressing the hyperactive liver and easing the stomach is arranged because of its nature and flavor acid, and the function of the Shujin that dries being controlled the convulsion of vomiting and diarrhoea, arthralgia chiefly caused by damp pathogen, beriberi, edema, dysentery.Select for use Myrrha to be because its nature and flavor hardship is flat, go into Liver Channel, diffusing blood blood stasis removing is arranged, the function of subduing swelling and relieving pain is controlled and is fallen damage, incised wound, muscles and bones, all Tong ， of trusted subordinate mass in the abdomen, amenorrhea, ulcer sore pain, anal fistula, diseases of the eye.

The specific embodiment

The drug dose of the present invention's combination also is that the inventor draws through groping in a large number to sum up, and the consumption of each component all has better curative effect in the following weight scope

Radix Et Rhizoma Rhei 25-35 gram Radix Achyranthis Bidentataes 26-34 gram Herba Lycopodiis 35-45 grams

Rhizoma Drynariae 35-45 gram Radix Solani Melongenae 45-55 gram Rhizoma Zingiberis Recenss 25-35 grams

Caulis Spatholobi the 45-55th grammes per square metre buildings 45-55 gram Radix Gentianae Macrophyllae, 30-40 grams

Cortex erythrinae 35-45 gram Fructus Ligustri Lucidi 45-55 gram Folium Salicis Babylonicaves 75-85 grams

Radix Angelicae Pubescentis 65-75 gram Fructus Tribulis 75-85 gram Spina Gleditsiae 25-35 grams

Radix Aconiti Kusnezoffii 25-35 gram Fructus Anisi Stellatis 25-35 gram Flos Carthamis 45-55 grams

Retinervus Luffae Fructus 45-55 gram Fructus Chaenomeliss 35-45 gram Myrrhas 20-30 grams

Mature vinegar 180-220 gram

Preferable amount is

Radix Et Rhizoma Rhei 30 gram Radix Achyranthis Bidentataes 28 gram Herba Lycopodiis 40 grams

Rhizoma Drynariae 40 gram Radix Solani Melongenae 50 gram Rhizoma Zingiberis Recenss 30 grams

Caulis Spatholobi the 50th grammes per square metre buildings 50 gram Radix Gentianae Macrophyllae, 35 grams

Cortex erythrinae 40 gram Fructus Ligustri Lucidi 50 gram Folium Salicis Babylonicaves 80 grams

Radix Angelicae Pubescentis 70 gram Fructus Tribulis 80 gram Spina Gleditsiae 30 grams

Radix Aconiti Kusnezoffii 30 gram Fructus Anisi Stellatis 30 gram Flos Carthamis 50 grams

Retinervus Luffae Fructus 50 gram Fructus Chaenomeliss 40 gram Myrrhas 25 grams

Mature vinegar 200 grams

The preparation method of medicine of the present invention is as follows

One, gets the raw materials ready

1, Radix Et Rhizoma Rhei: choose clean impurity, big or small stepping, stewing profit is even to inside and outside humidity, cuts into slices or is cut into small pieces, dries;

2, Radix Achyranthis Bidentatae: choose decontamination, clean, moisten softly, go reed, cutting is dried;

3, Herba Lycopodii: sieve dedust bits, choose clean impurity, be cut into segment;

4, Rhizoma Drynariae: remove clean sediment contamination, clean, soak slightly, run through, section is dried;

5, Radix Solani Melongenae: uproop when whole plant is withered, remove cured leaf, clean section, dry;

6, Rhizoma Zingiberis Recens: choose decontamination, clean earth, the time spent section;

7, Caulis Spatholobi: water runs through, section, or steam and take advantage of fervent sheet after soft, dry;

8, Rhizoma Paridis: remove fibrous root, cleaning, drying;

9, Radix Gentianae Macrophyllae: choose decontamination, except removing LU, soak slightly, run through section, dry;

10, Cortex erythrinae: soak with clear water, clean spare, be cut into small pieces, dry;

11, Fructus Ligustri Lucidi: choose decontamination, clean, dry;

12, Folium Salicis Babylonicae: get crude drug, choose decontamination;

13, Radix Angelicae Pubescentis: choose decontamination, separately size is individual, cleans, and runs through the back section, drying;

14, Fructus Tribuli: float silt, the hard thorn that Ex-all is residual;

15, Spina Gleditsiae: choose decontamination, be soaked in water, run through the back section, dry;

16, Radix Aconiti Kusnezoffii: get crude drug, remove impurity, cleaning, drying, the time spent smashs to pieces;

17, Fructus Anisi Stellati: sieve removes the spare seed, chooses fruit stem impurity;

18, Flos Carthami: choose clean impurity, remove stem and leaf, base of a fruit head, dry;

19, Retinervus Luffae Fructus: clean and dry cutting;

20, Fructus Chaenomelis: clear water is cleaned, and soaks slightly, and moistening is to saturating, puts in the food steamer to cook, and takes advantage of fervent sheet, and weather exposure is with by red commentaries on classics atropurpureus degree of being;

21, Myrrha: choose decontamination, break into fragment.

Two, preparation

Radix Et Rhizoma Rhei, Radix Achyranthis Bidentatae, Herba Lycopodii, Rhizoma Drynariae, Radix Solani Melongenae, Rhizoma Zingiberis Recens, Caulis Spatholobi, Rhizoma Paridis, Radix Gentianae Macrophyllae, Cortex erythrinae, Fructus Ligustri Lucidi, Folium Salicis Babylonicae, Radix Angelicae Pubescentis, Fructus Tribuli, Spina Gleditsiae, Radix Aconiti Kusnezoffii, Fructus Anisi Stellati, Flos Carthami, Retinervus Luffae Fructus, Fructus Chaenomelis, the Myrrha of described weight are decocted with water, add 10 times of amounts of water, soaked 90 minutes, decoct boiling 20 minutes with high heat, add mature vinegar 200 grams, namely got decoction liquor in 20 minutes with slow fire boiling again, after pouring into decoction liquor in the basin, treating that temperature is suitable can, foot is steeped into wherein, and the foot bath time is 20-30 minute.

Medicine of the present invention has antiinflammatory, analgesia, activating blood circulation to dissipate blood stasis, the network that stimulates the menstrual flow away, it is deep to have one's ideas straightened out, the effect of expelling wind and cold reinforcing the kidney to strengthen the bone, relaxing muscles and tendons and activating QI and blood in the collateral, and treatment talalgia instant effect, short treating period do not recur.

Below further set forth the beneficial effect of medicine of the present invention by testing example, these tests comprise that the animal toxicity test of medicine of the present invention reports and clinical observation material.

Below further set forth the beneficial effect of medicine of the present invention by testing example, these tests comprise that the animal toxicity test of medicine of the present invention and clinical observation test.

The animal toxicity test report of [test example 1] medicine of the present invention

Select 10 of new zealand rabbits for use, 10 rabbit abdominal part rabbit hairs are pulled out light, every rabbit is with medicine 20 grams of the present invention, smears the rabbit abdomen place after the depilation, with the gauze parcel, is used in conjunction 7 days every day three times, checks that the rabbit abdomen is normal, and 10 rabbit all do not have any untoward reaction.

By the test to new zealand rabbit, the result shows, uses Drug therapy of the present invention without any side effects by normal amount.

The clinical observation material of [test example 2] medicine of the present invention

1, physical data

Accept out-patient's 160 examples for medical treatment, its male patient's 90 examples, female patient 70 examples.

2, diagnostic criteria

Talalgia, it mainly shows as one-sided or bilateral heel or the bloated or prickling-like pain of foot bottom acid, the stride difficulty, heel lands namely bitterly.How because damaging, fat pad under the traumatic inflammation of sole of the foot fascia, peritenonitis of achilles tendon, calcaneus bursitis, calcanean spur and the calcaneus to cause that morbidity is how relevant with chronic strain.

3, Therapeutic Method

Select above-mentioned medicament for use, give patient's foot bath, every day early, evening, respectively once each 20-30 minute, 15 days was a course for the treatment of, uses 2 courses for the treatment of continuously.

4, efficacy assessment standard

Produce effects: transference cure, body constitution recover normal, observe 1 year no recidivist;

Take a turn for the better: symptom is clearly better, and symptom fades away;

Invalid: as not reach improvement standard person.

5, therapeutic outcome (seeing the following form)

In above-mentioned treatment, with Drug therapy talalgia patient 160 examples of the present invention, produce effects 150 examples as a result, obvious effective rate is 93.75%, 8 examples that take a turn for the better, improvement rate is 5%, invalid 2 examples, total effective rate is 98.75%.

Claims (3)

1. medicine for the treatment of talalgia, it is characterized in that: it is to be made by the crude drug in the following weight range:

Radix Et Rhizoma Rhei 25-35 gram Radix Achyranthis Bidentataes 26-34 gram Herba Lycopodiis 35-45 grams

Rhizoma Drynariae 35-45 gram Radix Solani Melongenae 45-55 gram Rhizoma Zingiberis Recenss 25-35 grams

Caulis Spatholobi the 45-55th grammes per square metre buildings 45-55 gram Radix Gentianae Macrophyllae, 30-40 grams

Cortex erythrinae 35-45 gram Fructus Ligustri Lucidi 45-55 gram Folium Salicis Babylonicaves 75-85 grams

Radix Angelicae Pubescentis 65-75 gram Fructus Tribulis 75-85 gram Spina Gleditsiae 25-35 grams

Radix Aconiti Kusnezoffii 25-35 gram Fructus Anisi Stellatis 25-35 gram Flos Carthamis 45-55 grams

Retinervus Luffae Fructus 45-55 gram Fructus Chaenomeliss 35-45 gram Myrrhas 20-30 grams

Mature vinegar 180-220 gram.

2. medicine according to claim 1, wherein the consumption of each crude drug is:

Radix Et Rhizoma Rhei 30 gram Radix Achyranthis Bidentataes 28 gram Herba Lycopodiis 40 grams

Rhizoma Drynariae 40 gram Radix Solani Melongenae 50 gram Rhizoma Zingiberis Recenss 30 grams

Caulis Spatholobi the 50th grammes per square metre buildings 50 gram Radix Gentianae Macrophyllae, 35 grams

Cortex erythrinae 40 gram Fructus Ligustri Lucidi 50 gram Folium Salicis Babylonicaves 80 grams

Radix Angelicae Pubescentis 70 gram Fructus Tribulis 80 gram Spina Gleditsiae 30 grams

Radix Aconiti Kusnezoffii 30 gram Fructus Anisi Stellatis 30 gram Flos Carthamis 50 grams

Retinervus Luffae Fructus 50 gram Fructus Chaenomeliss 40 gram Myrrhas 25 grams

Mature vinegar 200 grams.

3. according to the preparation method of claim 1 or 2 described medicines, it comprises the following steps:

(1) gets the raw materials ready

(1) Radix Et Rhizoma Rhei: choose clean impurity, big or small stepping, stewing profit is even to inside and outside humidity, cuts into slices or is cut into small pieces, dries;

(2) Radix Achyranthis Bidentatae: choose decontamination, clean, moisten softly, go reed, cutting is dried;

(3) Herba Lycopodii: sieve dedust bits, choose clean impurity, be cut into segment;

(4) Rhizoma Drynariae: remove clean sediment contamination, clean, soak slightly, run through, section is dried;

(5) Radix Solani Melongenae: uproop when whole plant is withered, remove cured leaf, clean section, dry;

(6) Rhizoma Zingiberis Recens: choose decontamination, clean earth, the time spent section;

(7) Caulis Spatholobi: water runs through, section, or steam and take advantage of fervent sheet after soft, dry;

(8) Rhizoma Paridis: remove fibrous root, cleaning, drying;

(9) Radix Gentianae Macrophyllae: choose decontamination, except removing LU, soak slightly, run through section, dry;

(10) Cortex erythrinae: soak with clear water, clean spare, be cut into small pieces, dry;

(11) Fructus Ligustri Lucidi: choose decontamination, clean, dry;

(12) Folium Salicis Babylonicae: get crude drug, choose decontamination;

(13) Radix Angelicae Pubescentis: choose decontamination, separately size is individual, cleans, and runs through the back section, drying;

(14) Fructus Tribuli: float silt, the hard thorn that Ex-all is residual;

(15) Spina Gleditsiae: choose decontamination, be soaked in water, run through the back section, dry;

(16) Radix Aconiti Kusnezoffii: get crude drug, remove impurity, cleaning, drying, the time spent smashs to pieces;

(17) Fructus Anisi Stellati: sieve removes the spare seed, chooses fruit stem impurity;

(18) Flos Carthami: choose clean impurity, remove stem and leaf, base of a fruit head, dry;

(19) Retinervus Luffae Fructus: clean and dry cutting;

(20) Fructus Chaenomelis: clear water is cleaned, and soaks slightly, and moistening is to saturating, puts in the food steamer to cook, and takes advantage of fervent sheet, and weather exposure is with by red commentaries on classics atropurpureus degree of being;

(21) Myrrha: choose decontamination, break into fragment;

(2) preparation

Radix Et Rhizoma Rhei, Radix Achyranthis Bidentatae, Herba Lycopodii, Rhizoma Drynariae, Radix Solani Melongenae, Rhizoma Zingiberis Recens, Caulis Spatholobi, Rhizoma Paridis, Radix Gentianae Macrophyllae, Cortex erythrinae, Fructus Ligustri Lucidi, Folium Salicis Babylonicae, Radix Angelicae Pubescentis, Fructus Tribuli, Spina Gleditsiae, Radix Aconiti Kusnezoffii, Fructus Anisi Stellati, Flos Carthami, Retinervus Luffae Fructus, Fructus Chaenomelis, the Myrrha of described weight are decocted with water, add 10 times of amounts of water, soaked 90 minutes, decoct boiling 20 minutes with high heat, add mature vinegar 200 grams, namely got decoction liquor in 20 minutes with slow fire boiling again, after pouring into decoction liquor in the basin, treating that temperature is suitable can, foot is steeped into wherein, and the foot bath time is 20-30 minute.