CN103191376A - Traditional Chinese medicine composition for treating chronic atrophic gastritis - Google Patents

Abstract

The invention discloses a traditional Chinese medicine composition for treating chronic atrophic gastritis. The composition adopts the following 18 components for compatibility: largehead atractylodes rhizome, orange fruit, nutgrass galingale rhizome, dangshen, coptis root, medicinal evodia fruit, almonds, sharpleaf galangal fruit, radix astragali, turmeric root tuber, medicated leaven, raw hawthorn, morinda root, weeping forsythia capsule, radix bupleuri, honeysuckle, akebia stem and white paeony root. The composition has obvious treatment effects on chronic gastritis, intestinal metaplasia accompanied by atrophic gastritis and atypical hyperplasia. The composition has the following pharmacological characteristics that the composition invigorates the spleen and supplements qi, harmonizes the liver and spleen, regulates qi and dissipates dampness, removes stasis to stop pains, softens hardness to break stones, nourishes and relaxes the liver, nourishes yin with sour and sweet herbs and can adjust the functions of pylorus, prevent backflow of bile and promote damaged tissue healing and gastric mucosa regeneration. The composition makes up for the deficiency of single traditional Chinese medicine preparations, solves the problems that the Western medicines fail to solve and toxic and side effects and has short course of treatment and low side effects.

Description

A kind of chronic atrophic gastritis Chinese medicine composition for the treatment of

Technical field:

The present invention relates to traditional Chinese medical science patent medicine, especially a kind of Chinese medicine composition for the treatment of chronic atrophic gastritis.

Background technology:

Chronic atrophic gastritis is a kind of common, chronic digestible tract disease, and doctor trained in Western medicine does not still have desirable Therapeutic Method to this at present.This disease belongs to the category of the traditional Chinese medical science " syndrome of feeling fullness and distension in the upper abdomen " " gastric abscess ", and the traditional Chinese medical science dialectical executes to control with symptomatic treatment still absolute advantages.

Summary of the invention:

Chronic atrophic gastritis is to have the course of disease long, pathological tissue is difficult for the characteristics of recovery, pathogen usually intruding into collateral in protracted disease, multiform becomes the deficiency of vital energy, characteristics such as qi depression to blood stasis, the present invention is directed to as above pathogenesis, adopt following prescription compatibility: the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii, Rhizoma Cyperi, Radix Codonopsis, Rhizoma Coptidis, Fructus Evodiae, Semen Armeniacae Amarum, Fructus Alpiniae Oxyphyllae, the Radix Astragali, Radix Curcumae, Massa Medicata Fermentata, Fructus Crataegi, Radix Morindae Officinalis, Fructus Forsythiae, Radix Bupleuri, Flos Lonicerae, Fructus Akebiae, the Radix Paeoniae Alba totally ten eight flavor Chinese medicines are formed.More than 18 the flavor Chinese medicines after selected drying, be prepared into watered pill, preparation method is seen " specific embodiment ".

The primary disease pathogenesis is that taste are impaired, and incoordination between the liver and stomach has void, gas, the wet all many-sides of the stasis of blood, and the major lesions position relates to liver, gallbladder, kidney, the heart, large intestine etc. at taste.Its main diseases is because there being many-side, and as eating cold and uncooked food excessively or pungent sweet fertilizer, hungry full forfeiting one's integrity pondered over and being overworked, and feelings will is unsuccessful, obstinate disease etc.The primary disease deficiency of spleen-QI and stomach-QI is this, and evil choke is strongly fragrant, and lifting mistake department is mark, and treatment is auxilliary based on benefit to lead to, reinforcement and elimination in combination, treating both the principal and the secondary aspects of a disease at the same time.Control suitable invigorating the spleen and benefiting QI stomach function regulating, regulating QI to expel dampness, logical stasis of blood pain relieving.The Radix Astragali, Radix Codonopsis, Rhizoma Atractylodis Macrocephalae invigorating the spleen and benefiting QI are for calling together in the side; Invigorating the spleen and benefiting QI energy facilitating digestion function is the road that effects a permanent cure, and the QI and blood of stomach is in harmonious proportion, thereby reaches the purpose of repairing gastric mucosa, Fructus Aurantii picric acid in the side, circulation of qi promoting removing blood stasis; Fructus Crataegi, Massa Medicata Fermentata help gastric qi and the broken knot of softening the hard mass; Radix Bupleuri focuses on the gas of dredging sharp liver spleen, makes the pylorus folding orderly, and bile is unlikely to backflow.Radix Bupleuri not only has antibiosis and antiviral functions, also has the anti-hypertrophy of exudation, and the protection gastric mucosa promotes effects such as cell regeneration, pushes away the most suitable that Chen Zhixin uses.It is antibiotic to join the Flos Lonicerae reinforcement, to eliminate the stomach inflammation; Radix Glycyrrhizae, the Radix Paeoniae Alba, the slow liver of easing the affected liver, sour livering the moon, the liver nourishing body, easing the affected liver usefulness is transferred the liver spleen, and collaborative Radix Bupleuri is regulated the pylorus function, prevents bile reflux.Promote the sick healing of decreasing tissue.Therefore, the present invention has remarkable therapeutic effect to chronic gastritis, atrophic gastritis companion's intestinal gland metaplasia and atypical hyperplasia.

Pharmacology characteristics of the present invention are as follows:

Invigorating the spleen and benefiting QI, regulating the liver and spleen, the spleen and stomach regulating, regulating QI to expel dampness, logical stasis of blood pain relieving, the broken knot of softening the hard mass, easing the affected liver delays liver, and sour livering the moon can be regulated the pylorus function, prevents bile reflux, promotes the sick organization healing of decreasing, and impels gastric mucosa regeneration.The present invention has filled up the deficiency of single medicinal material preparation, has solved the unsolved difficult problem of Western medicine and toxic and side effects, and short treating period, and side effect is little.

Through clinical verification, the present invention treats 66 routine chronic atrophic gastritis patients, cures 47 examples, accounts for 71.2%, and produce effects 14 examples account for 21.2%, and invalid 5 examples account for 7.5%, and total effective rate is 92.4%.

The specific embodiment:

Below in conjunction with specific embodiment, the invention will be further described:

1, a kind of Chinese medicine composition for the treatment of chronic atrophic gastritis of the present invention is made of by weight following 18 flavor Chinese crude drugs: Rhizoma Atractylodis Macrocephalae 30g, Fructus Aurantii 15g, Rhizoma Cyperi 20g, Radix Codonopsis 30g, Rhizoma Coptidis 10g, Fructus Evodiae 8g, Semen Armeniacae Amarum 15g, Fructus Alpiniae Oxyphyllae 10g, Radix Astragali 30g, Radix Curcumae 20g, Massa Medicata Fermentata 20g, Fructus Crataegi 30g, Radix Morindae Officinalis 15g, Fructus Forsythiae 15g, Radix Bupleuri 10g, Flos Lonicerae 30, Fructus Akebiae 20g, Radix Paeoniae Alba 20g.

2, a kind of preparation method for the treatment of the Chinese medicine composition of chronic atrophic gastritis:

It is that powder is standby that stone roller is dried in A, Flos Lonicerae, Fructus Akebiae, Fructus Evodiae, Semen Armeniacae Amarum, Fructus Alpiniae Oxyphyllae oven dry.

B, the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii, Rhizoma Cyperi, Radix Codonopsis, Rhizoma Coptidis, the Radix Astragali, Radix Bupleuri, the Radix Paeoniae Alba, Radix Curcumae, Massa Medicata Fermentata, Fructus Crataegi, Radix Morindae Officinalis, Fructus Forsythiae totally ten three flavor Chinese medicines are gone into pot and are added decocting in water and endure.

C, boil and endure 2 hours first, the leaching medicine juice is mixed to stir well with above-mentioned medicated powder and is dried or dry after even.The 2nd time, respectively add decocting in water the 3rd time to endure 1 hour, leaching medicine juice and medicated powder are mixed to stir well and are dried or dry after even respectively.

D, will cross 100 mesh sieves through stir the further porphyrize of medicated powder after drying or drying of 3 medicine juice, water is general be ball, big as Semen phaseoli radiati, and namely to invent a kind of Chinese medicine composition for the treatment of chronic atrophic gastritis be watered pill to preparation cost.

Usage and dosage: every day 2 times, one after each meal is used warm water delivery service, each 9g that is grown up, every month course for the treatment of sooner or later.

Model case:

Zhang, man, 48 years old, normal flu is uncomfortable, has the hiccups, returns acid, flatulence, presses superficial gastritis always, duodenal bulbar ulcer prolong control 2 years surplus, curative effect does not show, and violates during fashion, be diagnosed as " atrophic gastritis; superficial gastritis, reflux gastritis " the second half year in 2012 do gastroscopy, inscribe pulse-taking: having a double meaning weak pulse, white and the indentation of tongue, have a medical check-up: sclera does not have Huang seven, and the tone is humble, and the complexion white light is white, tcm diagnosis: incoordination between the liver and spleen, incoordination between the spleen and stomach, the wooden prosperous soil type that declines, throw watered pill of the present invention after 2 courses for the treatment of symptom subtract greatly, after obeying for two courses for the treatment of, all diseases are known nothing again.

Huge certain, the man, 55 years old, the cadre, flu portion feeling of distension and oppression sense often exacerbates after the food, shows through certain hospital gastroscope: " atrophic gastritis " invites surplus diagnosis and treatment, pulse condition: sliding number, tongue fur white edge point is red.The body sense is weak, Sleep hyperhidrosis as the washing, yellow complexion is dark, throw watered pill of the present invention after two courses for the treatment of patient's condition subtract greatly.Appetite is promoted, and nothing is known in the feeling of distension and oppression sense.After obeying a course for the treatment of again, confirm through microscopy: atrophic gastritis has transferred superficial gastritis to.

Liu, the woman, 60 years old, suffer from gastropathy, surplus the liver-gallbladder disease ten year, be diagnosed as chronic atrophic gastritis in microscopy recently, introduce the here diagnosis and treatment through the patient, throw pill of the present invention after two courses for the treatment of, patient's condition subtracts greatly, and the clothes that continue are again accused more for one course for the treatment of.

Claims (2)

1. a kind of Chinese medicine composition for the treatment of chronic atrophic gastritis of the present invention is characterized in that the weight of prescription compatibility and each Chinese medicine is: Rhizoma Atractylodis Macrocephalae 30g, Fructus Aurantii 15g, Rhizoma Cyperi 20g, Radix Codonopsis 30g, Rhizoma Coptidis 10g, Fructus Evodiae 8g, Semen Armeniacae Amarum 15g, Fructus Alpiniae Oxyphyllae 10g, Radix Astragali 30g, Radix Curcumae 20g, Massa Medicata Fermentata 20g, Fructus Crataegi 30g, Radix Morindae Officinalis 15g, Fructus Forsythiae 15g, Radix Bupleuri 10g, Flos Lonicerae 30, Fructus Akebiae 20g, Radix Paeoniae Alba 20g.

2. the preparation method that it is characterized in that this Chinese medicine composition:

It is that powder is standby that stone roller is dried in A, Flos Lonicerae, Fructus Akebiae, Fructus Evodiae, Semen Armeniacae Amarum, Fructus Alpiniae Oxyphyllae oven dry.

B, the Rhizoma Atractylodis Macrocephalae, Fructus Aurantii, Rhizoma Cyperi, Radix Codonopsis, Rhizoma Coptidis, the Radix Astragali, Radix Bupleuri, the Radix Paeoniae Alba, Radix Curcumae, Massa Medicata Fermentata, Fructus Crataegi, Radix Morindae Officinalis, Fructus Forsythiae totally ten three flavor Chinese medicines are gone into pot and are added decocting in water and endure.

C, boil and endure 2 hours first, the leaching medicine juice is mixed to stir well with above-mentioned medicated powder and is dried or dry after even.The 2nd time, respectively add decocting in water the 3rd time to endure 1 hour, leaching medicine juice and medicated powder are mixed to stir well and are dried or dry after even respectively.

D, will cross 100 mesh sieves through stir the further porphyrize of medicated powder after drying or drying of 3 medicine juice, water is general be ball, big as Semen phaseoli radiati, and namely to invent a kind of Chinese medicine composition for the treatment of chronic atrophic gastritis be watered pill to preparation cost.