CN103191349A - Traditional Chinese medicine preparation for treating nephritis - Google Patents

Traditional Chinese medicine preparation for treating nephritis Download PDF

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Publication number
CN103191349A
CN103191349A CN2013101429984A CN201310142998A CN103191349A CN 103191349 A CN103191349 A CN 103191349A CN 2013101429984 A CN2013101429984 A CN 2013101429984A CN 201310142998 A CN201310142998 A CN 201310142998A CN 103191349 A CN103191349 A CN 103191349A
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rhizoma
chinese medicine
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medicine preparation
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曹峰
韩刚
闫菲菲
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Abstract

The invention provides a traditional Chinese medicine preparation for treating nephritis, which has a good using effect. The traditional Chinese medicine preparation comprises the following medicines in parts by weight: 100-150g of radix astragali, 100-150g of rhizoma polygonatum, 50-80g of cortex phellodendri, 50-80g of oldenlandia diffusa, 100-150g of salvia miltiorrhiza, 30-60g of sichuan lovage rhizome, 150-180g of lalang grass rhizome, 100-150g of snow of june herb, 100-150g of rhizoma smilacis glabrae, 50-80g of radix rehmanniae and 50-92g of fructus ligustri lucidi. According to the traditional Chinese medicine preparation, the radix rehmannia, the rhizoma polygonatum and the fructus ligustri lucidi have a good effect of tonifying deficiency and essence, the lalang grass rhizome has a good effect of stopping bleeding, the oldenlandia diffusa, the snow of june herb and the rhizoma smilacis glabrae have good effects of being anti-inflammatory and subsiding swelling, the radix astragali has good effects of tonifying qi and solidifying spleen, the cortex phellodendri has good effects of discharging kidney fire and subsiding swelling, and the salvia miltiorrhiza and the sichuan lovage rhizome have a good effect of promoting blood circulation to remove blood stasis. After 30 patients aged between 18-60 with main symptoms of edema, oliguria, hematuresis and high blood pressure take the medicine, 27 of the 30 patients are healed, and the medicine is invalid for the other three patients; and the traditional Chinese medicine preparation has a good using effect.

Description

The Chinese medicine preparation for the treatment of nephritis
Technical field
The present invention relates to a kind of medicine for the treatment of nephritis, relate in particular to a kind of Chinese medicine preparation for the treatment of nephritis.
Background technology
Nephritis was divided according to the time, was divided into acute nephritis and chronic nephritis.
Acute nephritis is the abbreviation of acute glomerulonephritis, due to illness because of difference, has the people also to be referred to as the acute nephritis syndrome, and it is one group of Acute onset, reacts the diffusivity glomerule apyetous inflammatory lesion that causes because of premunition.Serve as main performance with edema, oliguria, hematuria and hypertension clinically, sick child's premorbid often has antecedent diseases such as flu, tonsillitis or skin purulent infection, primary disease is modal a kind of kidney disease in children's's period, is common in 3-8 year child, seldom sees below 2 years old.Prognosis is generally good, and the course of disease is 6 months to 1 year, develops into only only a few of chronic nephritis person.The minority infant can 1 week serious symptoms occur what fall ill, and as hypertensive encephalopathy, renal insufficiency, heart failure etc., so should pay close attention to primary disease, the concrete clinical manifestation of this disease has:
1. there are forerunners such as respiratory tract infection, skin infection and some viral infection to infect history more.
2. edema: start from eyelid, be descending property, non-pitting.
3. oliguria and hematuria: twenty-four-hour urine amount, infant are less than 200ml, and preschooler is less than 300ml, and school age population is less than 400ml.The gross hematuria color can be washes meat water sample or strong tea sample.
4. hypertension, blood pressure increase performances such as hypertension encephalopathy (HIE) such as headache, vomiting and tic, disturbance of consciousness can occur when obvious.
5. the congested performance of serious loop such as cough, tachypnea, cardiopalmus, pulmonary rale can be arranged.
Chronic nephritis is the abbreviation of chronic glomerulonephritis, can betide any age, but based on blue or green, middle-aged male, mode of onset and clinical manifestation are various.Most insidious onsets, slow are its basic clinical with hematuria, albuminuria, hypertension, edema.Generally speaking, all have urine examination unusual (hematuria, albuminuria, cylinderuria), edema and a hypertension history, and no matter course of disease delay has or not renal function injury all should consider this disease, and the inspection of kidney biopsy pathology can make a definite diagnosis and be conducive to instruct treatment and judging prognosis.Chronic nephritis should give corresponding treatment at its histological type in early days, suppresses immunomediated inflammatory, suppresses cell proliferation, alleviates the kidney sclerosis, and renal function goes down otherwise can have in various degree, and state of an illness delay, repeatedly gradually develops into chronic renal failure.
The Chinese patent medicine for the treatment of nephritis in the market is less, and major part is Western medicine or hormone, and not only toxicity is big, and effect is bad.
Summary of the invention
The Chinese medicine that the purpose of this invention is to provide the good treatment nephritis of a kind of result of use.
For achieving the above object, the technical solution used in the present invention is:
A kind of Chinese medicine preparation for the treatment of nephritis is characterized in that, it is made up of following parts of medicines by weight:
Radix Astragali 100-150 gram
Rhizoma Polygonati 100-150 gram
Cortex Phellodendri 50-80 gram
Herba Hedyotidis Diffusae 50-80 gram
Radix Salviae Miltiorrhizae 100-150 gram
Rhizoma Chuanxiong 30-60 gram
Rhizoma Imperatae 150-180 gram
Serissa foetida 100-150 gram
Rhizoma Smilacis Glabrae 100-150 gram
Radix Rehmanniae 50-80 gram
Fructus Ligustri Lucidi 50-92 gram.
In the present invention, the Radix Rehmanniae, Rhizoma Polygonati, Fructus Ligustri Lucidi tonify deficiency are mended smart, the Rhizoma Imperatae hemostasis, and Herba Hedyotidis Diffusae, Serissa foetida, Rhizoma Smilacis Glabrae anti-inflammation detumescence, the solid spleen of Radix Astragali QI invigorating, Cortex Phellodendri is rushed down kidney fire, detumescence, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong blood circulation promoting and blood stasis dispelling.30 patients are arranged, and the age, edema, oliguria, hematuria and hypertension were main performance between 18-60 year, took 27 recoveries from illness behind this medicine, and 3 invalid, and result of use is good.
The specific embodiment
Below in conjunction with specific embodiment the present invention is further described:
Embodiment one:
A kind of Chinese medicine preparation for the treatment of nephritis, it is made up of following parts of medicines by weight:
The Radix Astragali 100 grams
Rhizoma Polygonati 100 grams
Cortex Phellodendri 50 grams
Herba Hedyotidis Diffusae 50 grams
Radix Salviae Miltiorrhizae 100 grams
Rhizoma Chuanxiong 30 grams
Rhizoma Imperatae 150 grams
Serissa foetida 100 grams
Rhizoma Smilacis Glabrae 100 grams
The Radix Rehmanniae 50 grams
Fructus Ligustri Lucidi 50 grams.
In the present invention, the Radix Astragali, sweet, the tepor of nature and flavor is returned lung, spleen, liver, kidney channel, has benefiting QI for strengthening the superficies, arresting sweating to take off, hold in the palm the effect of skin ulcer granulation promoting, inducing diuresis to remove edema admittedly.Be used for the treatment of that the deficiency of vital energy is weak, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, the metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, carbuncle are difficultly burst, burst for a long time do not hold back, blood deficiency and yellow complexion, interior-heat are quenched one's thirst, chronic nephritis, albuminuria, diabetes etc.
Rhizoma Polygonati, nature and flavor are sweet, flat, return spleen, lung, kidney channel, effect with boosting qi and nourishing yin, spleen invigorating, lung moistening, kidney tonifying, cure mainly deficiency of YIN chronic cough, xeropulmonary cough, insufficiency of the spleen weak, lack of appetite xerostomia, quench one's thirst, deficiency of the kidney soreness of the waist and knees, impotence and seminal emission, tinnitus order are dark, early whitening of beard and hair, body are empty wins thin, wind favus disease, nourishing kidney lung moistening, invigorating the spleen and replenishing QI are used for the chronic cough chronic cough of lung-dryness syndrome due to deficiency of YIN, the few expectorant of dry cough and YIN-deficiency of the lung and kidney etc.
Cortex Phellodendri, nature and flavor hardship, cold is returned kidney, bladder, large intestine channel, and heat clearing and damp drying, eliminating fire and detoxication, except the hectic fever due to YIN-deficiency clearind deficient heat are used for that damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity are warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.
Herba Hedyotidis Diffusae, another name Herba Hedyotidis Diffusae, two leaf humulus, Herba Commelinae Bengalensis, Chinese Lobelia, short foot spend that Chinese Lobelia, tang Huang, the living pearl grass of order order, Herba Hedyotidis Diffusae, hill myna profit, thousand dozens are beaten in vain, Herba Turczaninowiae Fastigiatae, Radix Picriae felterrae, crane SHECAO, spire clumps of willow trees, the property bitter but sweet flavor, cold, nontoxic, be included into heart channel, Liver Channel, spleen channel, effect with heat-clearing and toxic substances removing, dampness removing cures mainly dyspnea and cough due to lung-heat, laryngopharynx swelling and pain, acute appendicitis, furuncle and phyma skin infection, venom, the puckery pain of pyretic stranguria, edema, dysentery, enteritis, jaundice due to damp-heat, cancerous protuberance.
Radix Salviae Miltiorrhizae, the nature and flavor hardship, be slightly cold, be included into the heart, Liver Channel, effect with promoting blood flow to regulate menstruation, stasis-dispelling and pain-killing, removing heat from blood eliminating carbuncle, the relieving restlessness that clears away heart-fire, nourishing blood to tranquillize the mind cures mainly that menoxenia, amenorrhea dysmenorrhea, lump in the abdomen, breast ventral spine pain, pyretic arthralgia pain, skin infection are swollen and ache, dysphoria and insomnia, hepatosplenomegaly, angina pectoris.
Rhizoma Chuanxiong, nature and flavor suffering, temperature are returned liver, gallbladder, pericardium channel, have the effect of blood-activating and qi-promoting, wind-expelling pain-stopping, cure mainly that stagnation of QI and blood is demonstrate,proved bitterly, headache, rheumatic arthralgia.
Rhizoma Imperatae, be grass perennial herb Herba Imperatae (formal name used at school: rhizome Imperata cylindrica), two seasons of spring and autumn excavate, dry, remove fibrous root and membranous sheath, cutting give birth to or parch to black usefulness, the another name Rhizoma Imperatae, manage, eat root, blue root, cure mainly cooling blood for hemostasis, heat-clearing and toxic substances removing, be used for haematemesis, hematuria, pyretic stranguria, edema, jaundice, dysuria, calentura excessive thirst, gastric heat vomit the sound of vomiting, cough.Effect removing heat from blood, hemostasis, heat clearing away, diuresis.Control calentura excessive thirst, haematemesis, epistaxis, lung-heat dyspnea with rapid respiration, gastric heat hiccup, gonorrhea, dysuria, edema, jaundice.
Rhizoma Imperatae decoct and water logging agent gavage, and normal rabbits is had diuresis, and administration 5-10 days, diuresis was the most obvious, and be namely not obvious about 20 days.
Serissa foetida, light, the little suffering of nature and flavor, cold have the effect that invigorating spleen to remove dampness, soothing liver-QI are invigorated blood circulation, and are used for infantile malnutrition, acute, chronic hepatitis, amenorrhea, leucorrhea, lumbago due to pathogenic wind-dampness.
Rhizoma Smilacis Glabrae, the another name Limonitum, white surplus grain, the grass Limonitum, the thorn Polyporus, Cortex Ampelopsis Aconitifoliae Radicis, hard meal, RHIZOMA SMILACIS GLABRAE, kadsurae coccineae, the mountain pig manure, the mountain region chestnut, it is outstanding to cross the ridge, the mountain cattle, cold meal head, SHANGUILAI, old potato of a specified duration, hair tail potato, ground Hu Ling, the old potato of Canis familiaris L., Radix Kadsurae Coccineae, hard meal head potato, the soil Siberian cocklebur, grain is lost on the mountain, the bright head of Canis familiaris L., the point shaven head, the mountain is hard, strange good, BAIQIA, connect meal, RHIZOMA SMILACIS GLABRAE, the property slightly sweet flavor, flat, return Liver Channel, the stomach warp, spleen channel, has detoxifcation, dehumidifying, the effect in sharp joint cures mainly and controls syphilis, stranguria with turbid discharge, the muscles and bones spasm and pain, beriberi, treat furuncle, carbuncle, scrofula, limbs contracture due to syphilis and the mercurialism, bones and muscles pain.
The Radix Rehmanniae, heat clearing away, promote the production of body fluid, moisturize, laxation, removing blood stasis with potent drugs, tissue regeneration promoting, pain relieving, regulating menstruation, the incised wound stasis of blood, removing heat from blood, hemostasis.
Fructus Ligustri Lucidi, nature and flavor are sweet, bitter, cool in nature, return liver, kidney channel, the effect that have liver and kidney tonifying, clearind deficient heat, makes eye bright, liver and kidney tonifying, crow must make eye bright, and cure mainly Light-headedness, soreness of the waist and knees, seminal emission, tinnitus, early whitening of beard and hair, osteopyrexia and fever, poor vision.
The present invention can make Chinese medicinal ointment with the processed with honey method, and method is as follows:
1, described medicine is put into Chinese medicine grinder, it is stand-by to be broken into powder;
2, refining Mel: often contain a spot of Cera Flava, microorganism and enzyme in the honey, and contain dead honeybee and dust, therefore Mel must can use through refining, method is earlier Mel to be placed in the pot, the water purification that adds 1/3-1/2, being heated to slowly boiling, dragging for most sweet edema over the face foam, with sieve sieve or the dead honeybee of gauze elimination, impurity.Filter is put behind the honey in the pot again and is concentrated with the slow fire heating, to the flake bubble that seethe with excitement, with the hands sth. made by twisting omit toughness, slightly during wire drawing, with saccharometer mensuration, water content is about 18%-20%, namely takes the dish out of the pot rapidly, puts cold standby.
3, medical material is inserted in the pot, when slow fire was fried to color burn, adding-quantitative refined honey stirred rapidly, and honey is mixed thoroughly with medical material, fried when tack-free, took out and treated that temperature makes cream and get final product.
In the method, medical material is 4:1 with refining close ratio, and unguentum is generally put into bowl, in order to take; Must cool after making cream, and airtight storage, in order to avoid the unguentum moisture absorption is clamminess or rotten; When honey is fried medical material, generally use slow fire, in case the medical material coking.
The present invention also can make honeyed pill, and the basic making step of honeyed pill is as follows:
1, the selection to Mel is the key that guarantees the honeyed pill quality with refining.The purpose of refined honey is to remove impurity, destroys ferment, kill microorganisms, and transpiring moisture strengthens viscosity.Its method is: the straight fire heating of limited production available copper pot or iron pan, slow fire refining; A large amount of production used vapour jacketed pans, reduction vaporization concentration pan are refined, and filter out impurities at last.The degree of refined honey is divided into three kinds of tender honey, refined honey, old honey.
Tender honey: be suitable for volume oil, phlegmatic temperament, the medicine pill of saccharide and animal tissue etc.
In honey: be suitable for cellulosic, starch and contain the part oils and fats, the general pill of saccharide.
Old honey: the mineral medicine pill that is suitable for containing volume cellulosic and viscosity difference.
2, the refined honey that will refine mixes (ratio of medicated powder and refined honey is generally 1:1 or 1:5, also has not enough 1:1's) in proportion with medicated powder, and is different and different according to pharmaceutical properties and season.The Chinese herbal medicine that generally contains saccharide, oils is few with honey.More and the open-textured medicine of cellulose is many with the honey amount.Summer is few with the honey amount, and winter is many with the honey amount.Imaging surface group sample ball piece is done in kneading equably.When closing medicine, Mel generally adds (as contain colloid, resin or volatile ingredient, need treat refined honey adds after cold slightly again mix) while hot, fully and even, it is inside and outsidely all moistened, the color and luster unanimity, and neither too hard, nor too soft, arbitrarily kneading model gets final product.
3, the dough sample soft material that gets togather is placed certain hour, spice is mixed with honey component to be moistened, and get final product rubbing after producing certain viscosity, the bar thickness unanimity that rubs with the big honeyed pills machine, smooth in appearance, make a certain amount of, smooth, the spherical pill in garden with the big honeyed pills machine again, produce available full-automatic big honeyed pills machine in a large number.(note when stirring medicated powder: Chinese medicine belongs to inviscid material, needs to add a certain proportion of pharmaceutic adjuvant, and the viscosity of powder is moderate when making pill, prevent too soft or too hard, stir tack-free getting final product.)
4, during pill, for avoiding the sticking hands of medicine group and sticking utensil, can use proper amount of lubricating agent during operation.Lubricant can be with glycerol or Oleum Sesami (Oleum Arachidis hypogaeae semen), Cera Flava by a certain percentage, heat fused forms.Summer, Cera Flava can suitably be added a bit.
5, packing and storage: the honeyed pill of making can adopt paraffin paper, cellophane, plastic bag, wax shell to wrap and be stored in shady and cool dry place.(annotate: be exposed to the sun under can not being placed on the sun to ready-made pill.)
Embodiment two:
A kind of Chinese medicine preparation for the treatment of nephritis, it is made up of following parts of medicines by weight:
The Radix Astragali 150 grams
Rhizoma Polygonati 150 grams
Cortex Phellodendri 80 grams
Herba Hedyotidis Diffusae 80 grams
Radix Salviae Miltiorrhizae 150 grams
Rhizoma Chuanxiong 60 grams
Rhizoma Imperatae 180 grams
Serissa foetida 150 grams
Rhizoma Smilacis Glabrae 150 grams
The Radix Rehmanniae 80 grams
Fructus Ligustri Lucidi 92 grams.
Other guide is with embodiment one.
Embodiment three:
A kind of Chinese medicine preparation for the treatment of nephritis, it is made up of following parts of medicines by weight:
The Radix Astragali 125 grams
Rhizoma Polygonati 125 grams
Cortex Phellodendri 65 grams
Herba Hedyotidis Diffusae 65 grams
Radix Salviae Miltiorrhizae 125 grams
Rhizoma Chuanxiong 45 grams
Rhizoma Imperatae 165 grams
Serissa foetida 125 grams
Rhizoma Smilacis Glabrae 125 grams
The Radix Rehmanniae 65 grams
Fructus Ligustri Lucidi 71 grams.
Other guide is with embodiment one.
Embodiment recited above is described preferred implementation of the present invention; be not that the spirit and scope of the present invention are limited; under the prerequisite that does not break away from design concept of the present invention; common engineers and technicians make technical scheme of the present invention in this area various modification and improvement; all should fall into protection scope of the present invention; the technology contents that the present invention asks for protection all is documented in claims.

Claims (4)

1. a Chinese medicine preparation for the treatment of nephritis is characterized in that, it is made up of following parts of medicines by weight:
Radix Astragali 100-150 gram
Rhizoma Polygonati 100-150 gram
Cortex Phellodendri 50-80 gram
Herba Hedyotidis Diffusae 50-80 gram
Radix Salviae Miltiorrhizae 100-150 gram
Rhizoma Chuanxiong 30-60 gram
Rhizoma Imperatae 150-180 gram
Serissa foetida 100-150 gram
Rhizoma Smilacis Glabrae 100-150 gram
Radix Rehmanniae 50-80 gram
Fructus Ligustri Lucidi 50-92 gram.
2. the Chinese medicine preparation for the treatment of nephritis according to claim 1 is characterized in that, it is made up of following parts of medicines by weight:
The Radix Astragali 100 grams
Rhizoma Polygonati 100 grams
Cortex Phellodendri 50 grams
Herba Hedyotidis Diffusae 50 grams
Radix Salviae Miltiorrhizae 100 grams
Rhizoma Chuanxiong 30 grams
Rhizoma Imperatae 150 grams
Serissa foetida 100 grams
Rhizoma Smilacis Glabrae 100 grams
The Radix Rehmanniae 50 grams
Fructus Ligustri Lucidi 50 grams.
3. the Chinese medicine preparation for the treatment of nephritis according to claim 1 is characterized in that, it is made up of following parts of medicines by weight:
The Radix Astragali 150 grams
Rhizoma Polygonati 150 grams
Cortex Phellodendri 80 grams
Herba Hedyotidis Diffusae 80 grams
Radix Salviae Miltiorrhizae 150 grams
Rhizoma Chuanxiong 60 grams
Rhizoma Imperatae 180 grams
Serissa foetida 150 grams
Rhizoma Smilacis Glabrae 150 grams
The Radix Rehmanniae 80 grams
Fructus Ligustri Lucidi 92 grams.
4. the Chinese medicine preparation for the treatment of nephritis according to claim 1 is characterized in that, it is made up of following parts of medicines by weight:
The Radix Astragali 125 grams
Rhizoma Polygonati 125 grams
Cortex Phellodendri 65 grams
Herba Hedyotidis Diffusae 65 grams
Radix Salviae Miltiorrhizae 125 grams
Rhizoma Chuanxiong 45 grams
Rhizoma Imperatae 165 grams
Serissa foetida 125 grams
Rhizoma Smilacis Glabrae 125 grams
The Radix Rehmanniae 65 grams
Fructus Ligustri Lucidi 71 grams.
CN2013101429984A 2013-04-24 2013-04-24 Traditional Chinese medicine preparation for treating nephritis Pending CN103191349A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103656538A (en) * 2013-12-31 2014-03-26 青岛市市立医院 Chinese medicinal preparation for treating hematuresis of latent glomerulonephritis

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101007151A (en) * 2006-01-23 2007-08-01 天津同仁堂股份有限公司 Traditional Chinese medicine and its preparation for treating chronic nephritis

Patent Citations (1)

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Publication number Priority date Publication date Assignee Title
CN101007151A (en) * 2006-01-23 2007-08-01 天津同仁堂股份有限公司 Traditional Chinese medicine and its preparation for treating chronic nephritis

Non-Patent Citations (2)

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王晗: "龚丽娟教授治疗肾炎经验探析", 《南京中医药大学学报》, vol. 26, no. 5, 30 September 2010 (2010-09-30), pages 324 - 326 *
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103656538A (en) * 2013-12-31 2014-03-26 青岛市市立医院 Chinese medicinal preparation for treating hematuresis of latent glomerulonephritis
CN103656538B (en) * 2013-12-31 2016-03-23 青岛市市立医院 Be used for the treatment of the Chinese medicine preparation of invisible glomerulonephritis hematuria

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Application publication date: 20130710