CN103191026A - 义齿安固膏 - Google Patents
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Abstract
本发明涉及一种具有抑菌、消炎、止血功能的义齿安固膏，由以下重量份数配比的原料组成：茶树油20-30、凡士林10-15、甲基乙烯基醚-马来酸酐共聚物的钙钠盐10-15、羧甲基纤维素30-35、尼泊金甲酯0.1-5、薄荷醇0.1-5、椒样油0.1-5、偶氮玉红0.5-15、二氧化硅0.1-5。本发明在义齿安固膏中添加茶树油，无毒副作用，具有广谱抗菌性，对很多厌氧菌、非厌氧菌均有优良的杀菌能力，可减轻牙龈发炎，促进口腔溃疡愈合，减轻咽喉肿痛的功效显著，安全、无刺激。
Description
技术领域：
本发明涉及一种医用口腔材料，尤其涉及一种具有抑菌、消炎、止血功能的茶树油义齿安固膏。
背景技术：
现在我国六十岁以上的老年人有一亿七千万，65岁以上老年人口总数已突破一亿大关，其中八十岁以上老年人有1900万。随着经济的发展，居民生活水平的提高，老年人的口腔健康越来越受到人们的重视。据专家调查，90％以上老年人有牙齿缺失，近50％老人镶复义齿。换言之，近8000万老年人使用义齿。
老年人齿槽骨条件较差，若种植假牙则易发生骨穿孔或骨裂，因此大多数老年人选用了活动义齿。活动义齿因为材质及设计的关系容易脱落，从而导致吃东西疼痛、说话不方便，也影响美观。
长期以来老年人在佩戴义齿过程中，义齿的松动和由此引发的一系列并发症，不仅严重的影响老人的口腔健康，同时也大大降低了老年人的生活品质。
从十八世纪人类开始使用义齿粘附剂，经过多年的发展和普及，在发达国家全口义齿人群中，许多人使用过此类义齿护理产品，在美国有75%的牙科医生推荐使用此类义齿护理产品来改善义齿使用者的舒适性，目前义齿粘附产品主要注重义齿在粘附性方面的改进，但对其抗菌性、杀菌能力及有效预防口腔感染的功效没有报道。
发明内容:
本发明的目的是提供一种具有抑菌、消炎、止血功能，对义齿佩戴者口腔常见的牙周炎、牙龈炎、牙龈出血、口腔溃疡、口臭等问题具有较好疗效的义齿安固膏。
为实现上述目的，本发明所采用的技术方案如下：
一种义齿安固膏，其特征在于由以下重量份数配比的原料组成：
茶树油 20 - 30
凡士林 10 - 15
甲基乙烯基醚-马来酸酐共聚物的钙钠盐 10 - 15
羧甲基纤维素 30- 35。
在上述技术方案的基础上，还可以进一步添加以下原料：
尼泊金甲酯 0.1 - 5
薄荷醇 0.1 – 5
椒样油 0.1 – 5
偶氮玉红 0.5 - 15
二氧化硅 0.1 - 5
本发明中的茶树油（Tea tree oil）按照植物学定义为互叶白千层油，它主要来自桃金娘科白千层属的互叶白千层（Melabeuca alternifolia）植物新鲜枝叶经水蒸汽蒸馏得到的无色至淡黄色的精油。本发明中使用的茶树油是通过水蒸气蒸馏或者有机溶剂从互叶白千层鲜叶和嫩枝中提取得到，主要成分是松油醇-4，其含量为30%-45%。
本发明的优点在于：义齿安固剂包含茶树油，茶树油具有广谱抗菌性，对很多厌氧菌、非厌氧菌均有优良的杀菌能力，其抗菌能力比苯酚强13倍，且皮肤渗透性好，作为功能性物料添加到义齿安固膏中，与现有的化学性消炎剂相比，茶树油对清除口腔厌氧菌的生长，减轻牙龈发炎，促进口腔溃疡愈合，减轻咽喉肿痛的功效显著，安全、无刺激，不会产生长时间使用而形成的微生物抗药性、牙齿变黄、口腔变干等负面影响。
本发明义齿安固膏中所含茶树油对不同菌株厌氧菌的最低抑菌浓度如下：
茶树油对厌氧菌的抑菌试验—最低抑菌浓度（MIC, %）
具体实施方式：
实施例1. 将纯度为96-99%的纯天然茶树油26g，凡士林15g放入反应釜中加热到70-90度搅拌2-3个小时，依次再加入甲基乙烯基醚-马来酸酐共聚物的钙钠盐15g，羧甲基纤维素35g，尼泊金甲酯2g，薄荷醇1g，椒样油1g，偶氮玉红2g，二氧化硅3g加热到70-90度搅拌3-4小时，冷凉、灌装制成。
实施例2. 将纯度为96-99%的纯天然茶树油茶树油25g，凡士林12g放入反应釜中加热到70-90度搅拌2-3个小时，依次再加入甲基乙烯基醚-马来酸酐共聚物的钙钠盐10g，羧甲基纤维素30g，尼泊金甲酯4g，薄荷醇2g，椒样油3g，偶氮玉红12g，二氧化硅2g加热到70-90度搅拌3-4小时，冷凉、灌装制成。
实施例3. 将纯度为96-99%的纯天然茶树油茶树油24g，凡士林14g放入反应釜中加热到70-90度搅拌2-3个小时，依次再加入甲基乙烯基醚-马来酸酐共聚物的钙钠盐12g，羧甲基纤维素32g，尼泊金甲酯3g，薄荷醇3g，椒样油4g，偶氮玉红7g，二氧化硅1g加热到70-90度搅拌3-4小时，冷凉、灌装制成。
实施例4. 将纯度为96-99%的纯天然茶树油茶树油27g，凡士林13g放入反应釜中加热到70-90度搅拌2-3个小时，依次再加入甲基乙烯基醚-马来酸酐共聚物的钙钠盐14g，羧甲基纤维素33g，尼泊金甲酯1g，薄荷醇4g，椒样油2g，偶氮玉红2g，二氧化硅4g加热到70-90度搅拌3-4小时，冷凉、灌装制成。
实施例5. 刘建国，男，73岁，义齿佩戴者，患有口腔溃疡反复发作近2年，病发时疼痛难忍，伴有口臭，严重影响进食。使用本发明的实施例2安固义齿，1天后可以正常进食，30日后口臭消失，疼痛症状缓解，继续使用60日后，口腔溃疡完全消失，至今未发。
实施例6. 宋家祥，女，68岁，义齿佩戴者，冠周炎，症状：冠周红肿，有脓性分泌物，剧烈疼痛。使用本发明的实施例4安固义齿，20日后疼痛感减少，连续使用30日后，肿胀消退，无脓性分泌物。
实施例7．王鼎一，男，80岁，义齿佩戴者，患有严重牙龈炎，饮食困难，病发时疼痛难忍，使用本发明的实施3安固义齿后，疼痛症状缓解，可以正常进食，继续使用30日后，牙龈肿痛消失，至今未发。
Claims (2)
1.一种义齿安固膏，其特征在于由以下重量份数配比的原料组成：
茶树油 20 - 30
凡士林 10 - 15
甲基乙烯基醚-马来酸酐共聚物的钙钠盐 10 - 15
羧甲基纤维素 30 - 35。
2.如权利要求1所述的义齿安固膏，其特征在于其组成中还含有以下重量份数配比的原料：
尼泊金甲酯 0.1 - 5
薄荷醇 0.1 - 5
椒样油 0.1 - 5
偶氮玉红 0.5 - 15
二氧化硅 0.1– 5。
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147527A (zh) * | 2015-10-10 | 2015-12-16 | 博爱新开源制药股份有限公司 | 一种义齿稳固剂 |
| CN112569123A (zh) * | 2020-12-18 | 2021-03-30 | 安徽克菱保健科技有限公司 | 一种低温挤出性好的义齿安固膏及其基质 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN87100010A (zh) * | 1987-01-02 | 1988-08-31 | 上海市牙病中心防治所 | 义齿粘附剂 |
| CN101991521A (zh) * | 2010-11-03 | 2011-03-30 | 中国热带农业科学院农产品加工研究所 | 一种茶树油漱口水及其制备方法 |
| CN102068388A (zh) * | 2011-01-06 | 2011-05-25 | 武汉大学 | 一种义齿粘附剂 |
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- 2013-04-20 CN CN201310138314.3A patent/CN103191026B/zh active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN87100010A (zh) * | 1987-01-02 | 1988-08-31 | 上海市牙病中心防治所 | 义齿粘附剂 |
| CN101991521A (zh) * | 2010-11-03 | 2011-03-30 | 中国热带农业科学院农产品加工研究所 | 一种茶树油漱口水及其制备方法 |
| CN102068388A (zh) * | 2011-01-06 | 2011-05-25 | 武汉大学 | 一种义齿粘附剂 |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105147527A (zh) * | 2015-10-10 | 2015-12-16 | 博爱新开源制药股份有限公司 | 一种义齿稳固剂 |
| CN112569123A (zh) * | 2020-12-18 | 2021-03-30 | 安徽克菱保健科技有限公司 | 一种低温挤出性好的义齿安固膏及其基质 |
| CN112569123B (zh) * | 2020-12-18 | 2023-04-11 | 安徽克菱保健科技有限公司 | 一种低温挤出性好的义齿安固膏及其基质 |
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