CN103190610A - Double-pigment soft capsule preparation and preparation method - Google Patents
Double-pigment soft capsule preparation and preparation method Download PDFInfo
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- CN103190610A CN103190610A CN2013100848853A CN201310084885A CN103190610A CN 103190610 A CN103190610 A CN 103190610A CN 2013100848853 A CN2013100848853 A CN 2013100848853A CN 201310084885 A CN201310084885 A CN 201310084885A CN 103190610 A CN103190610 A CN 103190610A
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Abstract
The invention provides a double-pigment soft capsule preparation and a preparation method. The preparation consists of an inclusion and a soft capsule shell, wherein the inclusion is prepared from dunaliella extract, lutein, beeswax and maize germ oil which are used as raw materials in a weight ratio; and the soft capsule shell is prepared from gelatin, glycerol, titanium dioxide, cocoa shell pigment and purified water which are used as raw materials in a weight ratio. The invention also discloses the preparation method for the double-pigment soft capsule preparation. The double-pigment soft capsule preparation, prepared from the dunaliella extract and the lutein which are used as the raw materials and are edible and pharmaceutical, is reasonable in formula and safe and reliable in administration, and can play a good role in reliving visual fatigue and improving body anti-oxidation for anti-oxidation reduced middle-aged and aged crowds and crowds using eyes frequently and feeling tired visually.
Description
Technical field
The present invention relates to the technical field of health product, especially a kind of pair of cellulose soft capsules preparation and preparation method.
Technical background
Quickening along with modern people's life, study, work rhythm, popularizing and application of TV, computer, and the influence that goes from bad to worse of natural environment, asthenopia has become one of common eye disease, have and report: the people of 10%-to 15% is arranged owing to produce headache and visual fatigue because before computer, working in the experimenter who carries out conventional eye examination, and this phenomenon has the trend of growth.
Aging is a kind of physiological phenomenon that each organ dysfunction of human body begins progressively to degenerate, show after deliberation: aging is because the result of the human body cell composition accumulation property oxidative damage that the human free radical reaction causes, free radical is one of major reason that causes human senility and many diseases, nearly 80%-90% aging according to statistics, degenerative disorders is relevant with free radical, human body with advancing age, the removing ability reduces because the free radical that human body produces increases, cause the bulk deposition of body free radical, damaging effect to body health is serious day by day, will accelerate the aging of body, cause the obstacle of body different physiological roles, in addition Wai Jie solar irradiation, air pollution, smoking, agricultural chemicals etc. all can make human body produce more active oxidation free radical.
Therefore the additional antioxidant of human body can well satisfy people for the injury that reduces the radical pair human body, reduces the human body visual fatigue, the demand of the old and feeble aspect of delaying human body body function.
Summary of the invention
Purpose of the present invention provides a kind of pair of cellulose soft capsules preparation with remarkable non-oxidizability and asthenopia releasing function and the preparation method of two cellulose soft capsules preparations.
In order to achieve the above object, the invention provides following technical scheme: a kind of pair of cellulose soft capsules preparation, formed by content and soft capsule, wherein content is by raw material salt algae extract, lutein, beeswax, maize germ oil is made according to weight ratio: salt algae extract 6%-10%, lutein 2.5%-4%, beeswax 3%-5%, surplus is maize germ oil; Wherein soft capsule shell is by the raw material gelatin, glycerine, and titanium dioxide, Cacao pigment, purified water is made according to weight ratio: gelatin 25%-40%, glycerine 15%-25%, titanium dioxide 1.5%-3%, Cacao pigment 1.5%-3%, surplus is purified water.
Salt algae extract purity is 8% in the foregoing thing.
Lutein purity is 75% in the foregoing thing.
The weight ratio of each raw material can be preferably in the foregoing thing: salt algae extract 6%, lutein 2.5%, beeswax 3%, maize germ oil 88.5%.
The weight ratio of each raw material can be preferably in the foregoing thing: salt algae extract 10%, lutein 4%, beeswax 5%, maize germ oil 81%.
The weight ratio of each raw material can be preferably in the foregoing thing: salt algae extract 8%, lutein 3.2%, beeswax 20%, maize germ oil 84.8%.
The weight proportion of above-mentioned each raw material of soft capsule shell can be preferably: gelatin 36%, glycerine 20%, titanium dioxide 2%, Cacao pigment 2%, purified water 40%.
Above-mentioned pair of cellulose soft capsules preparation can prepare by the method that comprises following key step:
1) raw material mixes:
Get the salt algae extract of described proportioning, maize germ oil with colloid mill pulverize mixture I, get lutein, the beeswax of described proportioning, the method that increases progressively with equivalent with mixture I, with colloid mill pulverize the II mixtures II;
2) preparation glue:
Adding an amount of purified water in gelatin fully expands gelatin; With being heated to 70 ℃ in glycerine, titanium dioxide, Cacao pigment, remaining placing of the purified water glue jar, stir, add the gelatin that expands and stir, make to be melt into even glue, be incubated 1.5 hours, skim the floating foam of liquid level, filter glue through 150 mesh sieves, place that to sprawl case stand-by;
3) be pressed into capsule:
Mixtures II and glue are made capsule by automatic rotation rolling capsule machine, and in the capsule pressing process, indoor temperature remains on 20-24 ℃, and air humidity remains on 45-50%;
4) typing: the capsule that has just suppressed, because its temperature is higher, the softgel shell water content is bigger, the shape instability, the processing of need finalizing the design: in the rotary roller typing, forced air drying 3-7 hour, preferred 4 hours;
5) cleaning treatment: the capsule that typing is handled well uses 95% alcohol flushing capsule surface oil reservoir;
6) drying: capsule is placed on hothouse, remains on 30-40 in air humidity, temperature remains under 24-28 ℃ the environment, namely obtains two cellulose soft capsules preparations in static dry 24 hours.
Described step also comprises 7) packing: be about to two cellulose soft capsules preparations and screen, reject the capsule of distortion, the profile of breaking, the capsule that will meet the finished product requirement carries out inner packing, is encapsulated in the medicinal high density ethylene bottle, and being divided into marketing packing again behind check problem namely becomes the finished product that can dispatch from the factory.
Two cellulose soft capsules preparations that the present invention makes; salt algae extract Wheat Protein; but nutrition human body cell; effectively alleviate or elimination visual fatigue; lutein is enrichment on retina; can improve the GJIC function, keep amphiblestroid normal vision, the protection retina is avoided the blue light damage; suppress; the cancellation free radical; salt algae extract and lutein share, reasonable recipe, and raw material belongs to integration of drinking and medicinal herbs; take safe and reliable; for mid-aged population and warp eye commonly used that antioxidative functional reduces, the alleviation visual fatigue that the crowd of visual fatigue can get up good improves the oxidation resistant usefulness of body.
Description of drawings
In order to be illustrated more clearly in the embodiment of the invention or technical scheme of the prior art, to do to introduce simply to the accompanying drawing of required use in embodiment or the description of the Prior Art below, apparently, accompanying drawing in describing below only is some embodiments of the present invention, for those of ordinary skills, under the prerequisite of not paying creative work, can also obtain other accompanying drawing according to these accompanying drawings.
Fig. 1 is preparation method's of the present invention flow chart.
The specific embodiment
Below in conjunction with accompanying drawing of the present invention, technical scheme of the present invention is clearly and completely described, obviously, described embodiment only is the present invention's part embodiment, rather than whole embodiment.Based on the embodiment among the present invention, those of ordinary skills belong to the scope of protection of the invention not making the every other embodiment that obtains under the creative work prerequisite.
The salt algae is a kind of unicellular eucaryon algae, is one of eucaryote of the salt tolerant found up to now, and the salt algae is high temperature resistant cold-resistant again throughout the year, it is advantageous that its contained content beta-carotene than carrot height to 60-160 doubly.The same with other natural materials, algae carrotene has the wide spectrum effect of carrotene, yet many evidences show that some function of beta carotene is different from it as provitamin A, and its function is can the quencher singlet oxygen and remove free radical as antioxidant.Beta carotene is the terminating chain reaction by Mulberry Extract, it is a kind of uncommon lipid antioxidant, this is because it is the most effective under away from the low oxygen concentration environment that directly exposes with the capillary bed of oxygen, takes in a large amount of beta carotenes vitamin a level is increased unusually.
Experiment shows: salt algae extract can obviously reduce LPO content in blood and the liver, improves SOD and GSH-Px activity, have anti-oxidant, delay senility about.Epidemiological study shows: the incidence of beta carotene and vitamin a level and tumour is negative correlation in the body.And the research surface is arranged: the anti-oxidation function of tumor patient is beneath relevant with cancer metastasis.Take the anti-oxidation function that the salt algae will be improved body for a long time, thereby suppress recurrence and the transfer of cancer, anti-oxidation function and the immunologic function of body are closely related, because free radical causes immunosupress.And beta carotene has the immunity of organism of enhancing and oxidation resistant effect.Therefore, can promote body to the killing and wounding of tumour cell, its effect is extensive, nontoxic, and the source is abundant, and prevention and the treatment of malignant tumour had positive effect.
Salt algae beta carotene has the non-specific body fluid of promotion and cellular immune function, and is particularly evident to the left and right sides of T lymphopoiesis and t lymphocyte subgroup.The damage of beta carotene facedown lipid peroxidation of erythrocyte membrane, the destruction that alleviates C3b receptor is improved its activity, has increased immune adherence and lethal effect to tumour cell.
Salt algae beta carotene has anti peroxidation of lipid damage ability as antioxidant, reduces the serum MDA, (MDA) reduces the content of arterial wall cholesterol (TC) cholesteryl ester (CE) and MDA.Endarterium there is protective effect and stops its foamed, effectively generation and the development of prevention of arterial sclerosis pathology, and be dose-dependence.The atherosis theoretical foundation that provides of clinical practice antioxidant prevention of arterial is provided in this research.There are some researches show: the lipid-metabolism wadding disorderly, on the basis of radical damage and artery sclerosis correlation, for generation and the development of beta carotene prevention of arterial sclerosis pathology provides test basis, the oral effect with prevention of arterial sclerosis of proof beta carotene has supported antioxidant to prevent the neodoxy of coronary heart disease.Atherosclerotic is the pathologic basis of cardiovascular and cerebrovascular disease.Its generation, development and fat metabolism wadding are disorderly in close relations, particularly closely related with the deposition of oxidized low density lipoprotein, beta carotene is fat-soluble antioxidant in the human body, mainly act on MDA, suppress the peroxidating of unrighted acid on the membranous structure.
Lutein is a kind of oxygen containing carotenoid, and main the participation constitutes macular pigment in the retina in human body, is distributed in macular area and whole retina, and it can absorb the photoreceptor short-wavelength light, so the effect of protection retina and the anti-light injury of macular area is arranged.
Lutein is enrichment on retina, can not only improve the GJIC function, keeps amphiblestroid normal vision, and can suppress the photosensory cell apoptosis that caused by light injury, plays crucial effects in the protection retinal light damage.Discover the high people of retina lutein concentration, corresponding photopic vision, scotopia and the sensitivity level of the section glistening light of waves is significantly higher than the low people of retina lutein concentration.The wavelength of blue light (435～480nm) with the wavelength of ultraviolet (400～435nm) is very near; it is the highest that it is that all can reach in the amphiblestroid visible light energy; a kind of light of potential hazard maximum; he can cause retinal pigment epithelium and photosensory cell damage; and the maximum absorption wavelength of lutein just is in the wave-length coverage of blue light; it forms the blue light filter in the human eye retina; reduce the probability that blue light arrives photoreceptor and retinal neuronal cell; thereby the retina cell had protective effect; the eyes retina tissue needs the amount of oxidation height; redox reaction is active; lutein can with cell membrane on contaminated with lipid; the oxidation reaction that suppresses lipid effectively alleviates oxidation product to amphiblestroid murder by poisoning, thereby reaches the effect of protection retinal tissue.Lutein can stop the biomembranous infringement of radical pair, and cancellation singlet oxygen and catch active oxygen radical has specific antioxidation.Conjugated double bond in its molecule of the oxidation resistance of lutein is closely related, and lutein has the attack of a plurality of conjugated double bonds, is a kind of agent for capturing of effective peroxylradicals, and especially effect is better under the low oxygen pressure of living cell tissue.Lutein is the most effective oxygen radical quencher in the existing natural carotenoid, and is all higher than the cancellation speed of other any carrotene, and this may be relevant with exist two extra non-covalent pair of keys in its molecule.Therefore, the plain generation by the inhibition free radical of lutein, thereby aging and some infirmities of age of prevention body.
As embodiment, be embodiment to make 1000 two cellulose soft capsules preparations.
Formulation selection:
Capsule 's content: embodiment takes formula material according to weight, gets purity and be 8% salt algae extract 40 grams, and purity is 75% lutein 16 grams, beeswax 20 grams, maize germ oil 424 grams.
Soft capsule shell: embodiment takes formula material according to weight, gets gelatin 90 grams, glycerine 50 grams, titanium dioxide 5 grams, Cacao pigment 5 grams, purified water 100 grams.
Two cellulose soft capsules preparations that above-mentioned prescription is made, the tolerant content of every intragranular are 0.5 gram, according to experiment showed, that each one can reach anti-oxidant, alleviates the effect of visual fatigue according to becoming body weight for humans 60KG meter, adult to take once every day.
According to shown in Figure 1, two cellulose soft capsules preparations can prepare by the method that comprises following key step:
1) raw material mixes:
Get the salt algae extract of described proportioning, maize germ oil with colloid mill pulverize mixture I, get lutein, the beeswax of described proportioning, the method that increases progressively with equivalent with mixture I, with colloid mill pulverize the II mixtures II;
2) preparation glue:
Adding an amount of purified water in gelatin fully expands gelatin; With being heated to 70 ℃ in glycerine, titanium dioxide, Cacao pigment, remaining placing of the purified water glue jar, stir, add the gelatin that expands and stir, make to be melt into even glue, be incubated 1.5 hours, skim the floating foam of liquid level, filter glue through 150 mesh sieves, place that to sprawl case stand-by;
3) be pressed into capsule:
Mixtures II and glue are made capsule by automatic rotation rolling capsule machine, and in the capsule pressing process, indoor temperature remains on 20-24 ℃, and air humidity remains on 45-50%;
4) typing: the capsule that has just suppressed, because its temperature is higher, the softgel shell water content is bigger, the shape instability, the processing of need finalizing the design: in the rotary roller typing, forced air drying 3-7 hour, preferred 4 hours;
5) cleaning treatment: the capsule that typing is handled well uses 95% alcohol flushing capsule surface oil reservoir;
6) drying: capsule is placed on hothouse, remains on 30-40 in air humidity, temperature remains under 24-28 ℃ the environment, namely obtains two cellulose soft capsules preparations in static dry 24 hours.
Described step also comprises 7) packing: be about to two cellulose soft capsules preparations and screen, reject the capsule of distortion, the profile of breaking, the capsule that will meet the finished product requirement carries out inner packing, is encapsulated in the medicinal high density ethylene bottle, and being divided into marketing packing again behind check problem namely becomes the finished product that can dispatch from the factory.Screen for two cellulose soft capsules preparations that will complete in the step 7), reject the capsule of distortion, the profile of breaking, the capsule that will meet the finished product requirement carries out inner packing, be encapsulated in the medicinal high density ethylene bottle, behind check problem, be divided into the marketing packing supervisor again, all are steps necessarys of suitability for industrialized production, so no longer give unnecessary details among the present invention.
The above; only be the specific embodiment of the present invention, but protection scope of the present invention is not limited thereto, anyly is familiar with those skilled in the art in the technical scope that the present invention discloses; can expect easily changing or replacing, all should be encompassed within protection scope of the present invention.Therefore, protection scope of the present invention should be as the criterion by described protection domain with claim.
Claims (9)
1. two cellulose soft capsules preparation, it is characterized in that: formed by content and soft capsule, wherein content is by raw material salt algae extract, lutein, beeswax, maize germ oil is made according to weight ratio: salt algae extract 6%-10%, lutein 2.5%-4%, beeswax 3%-5%, surplus is maize germ oil; Wherein soft capsule shell is by the raw material gelatin, glycerine, and titanium dioxide, Cacao pigment, purified water is made according to weight ratio: gelatin 25%-40%, glycerine 15%-25%, titanium dioxide 1.5%-3%, Cacao pigment 1.5%-3%, surplus is purified water.
2. a kind of pair of cellulose soft capsules preparation according to claim 1, it is characterized in that: salt algae extract purity is 8% in the described content.
3. a kind of pair of cellulose soft capsules preparation according to claim 1, it is characterized in that: lutein purity is 75% in the described content.
4. according to the arbitrary described a kind of pair of cellulose soft capsules preparation of claim 1 to 3, it is characterized in that: the weight ratio of each raw material can be preferably in the described content: salt algae extract 6%, lutein 2.5%, beeswax 3%, maize germ oil 88.5%.
5. according to the arbitrary described a kind of pair of cellulose soft capsules preparation of claim 1 to 3, it is characterized in that: the weight ratio of each raw material can be preferably in the described content: salt algae extract 10%, lutein 4%, beeswax 5%, maize germ oil 81%.
6. according to the arbitrary described a kind of pair of cellulose soft capsules preparation of claim 1 to 3, it is characterized in that: the weight ratio of each raw material can be preferably in the described content: salt algae extract 8%, lutein 3.2%, beeswax 20%, maize germ oil 84.8%.
7. according to the arbitrary described a kind of pair of cellulose soft capsules preparation of claim 1 to 3, it is characterized in that: the weight proportion of described each raw material of soft capsule shell can be preferably: gelatin 36%, glycerine 20%, titanium dioxide 2%, Cacao pigment 2%, purified water 40%.
8. a right to use requires the preparation method of 1 to 7 arbitrary pairs cellulose soft capsules preparations, it is characterized in that: may further comprise the steps:
1) raw material mixes:
Get the salt algae extract of described proportioning, maize germ oil with colloid mill pulverize mixture I, get lutein, the beeswax of described proportioning, the method that increases progressively with equivalent with mixture I, with colloid mill pulverize the II mixtures II;
2) preparation glue:
Adding an amount of purified water in gelatin fully expands gelatin; With being heated to 70 ℃ in glycerine, titanium dioxide, Cacao pigment, remaining placing of the purified water glue jar, stir, add the gelatin that expands and stir, make to be melt into even glue, be incubated 1.5 hours, skim the floating foam of liquid level, filter glue through 150 mesh sieves, place that to sprawl case stand-by;
3) be pressed into capsule:
Mixtures II and glue are made capsule by automatic rotation rolling capsule machine, and in the capsule pressing process, indoor temperature remains on 20-24 ℃, and air humidity remains on 45-50%;
4) typing: the capsule that has just suppressed, because its temperature is higher, the softgel shell water content is bigger, the shape instability, the processing of need finalizing the design: in the rotary roller typing, forced air drying 3-7 hour, preferred 4 hours;
5) cleaning treatment: the capsule that typing is handled well uses 95% alcohol flushing capsule surface oil reservoir;
6) drying: capsule is placed on hothouse, remains on 30-40 in air humidity, temperature remains under 24-28 ℃ the environment, namely obtains two cellulose soft capsules preparations in static dry 24 hours.
9. the preparation method of according to claim 8 pair of cellulose soft capsules preparation, it is characterized in that: also comprise 7) packing: be about to two cellulose soft capsules preparations and screen, reject the capsule of distortion, the profile of breaking, the capsule that will meet the finished product requirement carries out inner packing, be encapsulated in the medicinal high density ethylene bottle, being divided into marketing packing again behind check problem namely becomes the finished product that can dispatch from the factory.
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104523815A (en) * | 2014-12-18 | 2015-04-22 | 南宁富莱欣生物科技有限公司 | Soft capsules and production method thereof |
| CN105012670A (en) * | 2015-07-23 | 2015-11-04 | 高峰 | Ginseng and rana japonica oil soft capsule and preparation method thereof |
| CN105341929A (en) * | 2015-12-02 | 2016-02-24 | 烟台燕园科玛健康产业有限公司 | Health-care food composition capable of alleviating asthenopia |
| CN105341946A (en) * | 2015-12-14 | 2016-02-24 | 北京康比特体育科技股份有限公司 | Dunaliella salina, lutein and huckleberry composition, soft capsule containing composition and preparation method of soft capsule |
| CN107518357A (en) * | 2017-08-25 | 2017-12-29 | 深圳市康道生物有限公司 | A kind of enhancing immune composition containing Effects of Extracts of Grifola frondosa on Active and preparation method thereof |
| CN108391816A (en) * | 2017-02-08 | 2018-08-14 | 阙燕娣 | A kind of production method of antioxidant healthcare capsule |
| CN108669555A (en) * | 2018-04-17 | 2018-10-19 | 北京中和鸿业医药科技有限公司 | A kind of Algal Assemblages object, preparation, preparation method and applications |
| CN111053143A (en) * | 2019-11-28 | 2020-04-24 | 北京美宝高科技有限责任公司 | Green and healthy sandwich gel candy rich in nutrition and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1429544A (en) * | 2003-01-13 | 2003-07-16 | 内蒙古吉兰泰盐化集团呼和浩特制药厂 | Natural carotene soft capsule and its production method |
| CN101019914A (en) * | 2007-03-23 | 2007-08-22 | 童宥霖 | Soft capsule containing lutein and its prepn |
| CN101856118A (en) * | 2010-03-23 | 2010-10-13 | 无锡市天赐康生物科技有限公司 | Health-care food for relieving asthenopia and preparation method thereof |
| CN101904502A (en) * | 2010-08-03 | 2010-12-08 | 晨光生物科技集团天津有限公司 | Compound xanthophyll soft capsule and preparation method |
| US20130004570A1 (en) * | 2005-08-04 | 2013-01-03 | Vertical Pharmaceuticals, Inc. | Nutritional supplement for use under physiologically stressful conditions |
| CN102960738A (en) * | 2012-12-20 | 2013-03-13 | 汤臣倍健股份有限公司 | Bilberry and lutein soft capsule and preparation method thereof |
-
2013
- 2013-03-18 CN CN2013100848853A patent/CN103190610A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1429544A (en) * | 2003-01-13 | 2003-07-16 | 内蒙古吉兰泰盐化集团呼和浩特制药厂 | Natural carotene soft capsule and its production method |
| US20130004570A1 (en) * | 2005-08-04 | 2013-01-03 | Vertical Pharmaceuticals, Inc. | Nutritional supplement for use under physiologically stressful conditions |
| CN101019914A (en) * | 2007-03-23 | 2007-08-22 | 童宥霖 | Soft capsule containing lutein and its prepn |
| CN101856118A (en) * | 2010-03-23 | 2010-10-13 | 无锡市天赐康生物科技有限公司 | Health-care food for relieving asthenopia and preparation method thereof |
| CN101904502A (en) * | 2010-08-03 | 2010-12-08 | 晨光生物科技集团天津有限公司 | Compound xanthophyll soft capsule and preparation method |
| CN102960738A (en) * | 2012-12-20 | 2013-03-13 | 汤臣倍健股份有限公司 | Bilberry and lutein soft capsule and preparation method thereof |
Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104523815A (en) * | 2014-12-18 | 2015-04-22 | 南宁富莱欣生物科技有限公司 | Soft capsules and production method thereof |
| CN105012670A (en) * | 2015-07-23 | 2015-11-04 | 高峰 | Ginseng and rana japonica oil soft capsule and preparation method thereof |
| CN105012670B (en) * | 2015-07-23 | 2018-08-21 | 高峰 | Ginseng Wood frog oil soft capsule and preparation method thereof |
| CN105341929A (en) * | 2015-12-02 | 2016-02-24 | 烟台燕园科玛健康产业有限公司 | Health-care food composition capable of alleviating asthenopia |
| CN105341946A (en) * | 2015-12-14 | 2016-02-24 | 北京康比特体育科技股份有限公司 | Dunaliella salina, lutein and huckleberry composition, soft capsule containing composition and preparation method of soft capsule |
| CN108391816A (en) * | 2017-02-08 | 2018-08-14 | 阙燕娣 | A kind of production method of antioxidant healthcare capsule |
| CN107518357A (en) * | 2017-08-25 | 2017-12-29 | 深圳市康道生物有限公司 | A kind of enhancing immune composition containing Effects of Extracts of Grifola frondosa on Active and preparation method thereof |
| CN108669555A (en) * | 2018-04-17 | 2018-10-19 | 北京中和鸿业医药科技有限公司 | A kind of Algal Assemblages object, preparation, preparation method and applications |
| CN111053143A (en) * | 2019-11-28 | 2020-04-24 | 北京美宝高科技有限责任公司 | Green and healthy sandwich gel candy rich in nutrition and preparation method thereof |
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Address after: 100070 No. 4, building 128, South Fourth Ring Road, Fengtai District, Beijing, 909 Applicant after: BEIJING BO YUAN SCIENCE AND TECHNOLOGY CO., LTD. Address before: 100077 Beijing city Fengtai District Fung Fu Road No. 2 2-20 Applicant before: Beijing Boyuan Xinlv Technology Co., Ltd. |
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Application publication date: 20130710 |