CN103185769A - Integrated device for biochemical reaction - Google Patents

Integrated device for biochemical reaction Download PDF

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Publication number
CN103185769A
CN103185769A CN2011104430414A CN201110443041A CN103185769A CN 103185769 A CN103185769 A CN 103185769A CN 2011104430414 A CN2011104430414 A CN 2011104430414A CN 201110443041 A CN201110443041 A CN 201110443041A CN 103185769 A CN103185769 A CN 103185769A
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China
Prior art keywords
cup
filling
cup body
biochemical reaction
integrated device
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CN2011104430414A
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Chinese (zh)
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CN103185769B (en
Inventor
王滨
吴一凡
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SUZHOU DIAGVITA BIOTECHNOLOGY CO Ltd
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SUZHOU DIAGVITA BIOTECHNOLOGY CO Ltd
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Priority to CN201110443041.4A priority Critical patent/CN103185769B/en
Publication of CN103185769A publication Critical patent/CN103185769A/en
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Abstract

The invention provides an integrated device for biochemical reaction. The integrated device for biochemical reaction comprises a first cup body and a second cup body, wherein the first cup body is provided with a reactant storage chamber 1 for accommodating reactants, and the second cup body is provided with a reactant storage chamber 2 for accommodating the reactants; a through hole is formed in the bottom of the second cup body; a sealing plug or a sealing film is arranged on the through hole, or a thin wall is integrally formed on the through hole; a filling device is further sleeved in the reactant storage chamber 2, and a reagent can be quantitatively and hermetically placed in the reactant storage chamber 2 of the second cup body in advanced. The product can be produced in batches; during a test, a detection reaction is finished only by taking off the second cup body from the first cup body, then quantitatively putting the to-be-detected substance in the reactant storage chamber 1 of the second cup body, then connecting the second cup body with the first cup body, pushing the filling device, and injecting the reagent in the second cup body into the first cup body; and the needed reactants can also be put in the first cup body in advanced as needed. With the adoption of the device, the whole test is convenient and fast, thus greatly increasing the working efficiency.

Description

A kind of biochemical reaction integrated device
Technical field
The present invention relates to the biochemical reaction apparatus field, be specifically related to a kind of biochemical reaction integrated device.
Background technology
At present at biology/chemical laboratory or medical industry detection range, when need do a certain reaction test, general quantitative extraction earlier material to be checked is put into reaction vessel, and then quantitatively extract particular agent and add in this reaction vessel, the two is reacted, and measure its reaction result data, running time is longer, do a large amount of same class testings as need, time and effort consuming then, inefficiency.
Summary of the invention
The objective of the invention is at the problems referred to above, a kind of a kind of biochemical reaction integrated device of conveniently finishing test process is provided.
For achieving the above object, technical scheme provided by the invention is a kind of biochemical reaction integrated device, comprise first cup and second cup, described first cup is provided with reactant 1 apotheca that holds reactive material, and described second cup is provided with reactant 2 apothecas that hold reactive material
The upper end of the described second cup lower end and described first cup is provided with the connecting portion of mutual coupling, and separable being serially connected, and the wall of cup of the bottom of described second cup and first cup forms reactant 1 apotheca of sealing,
The bottom of described second cup is provided with a through hole, and described through hole is provided with sealing-plug or diaphragm seal, or one-body molded thin-walled is arranged,
Also be arranged with filling apparatus in described reactant 2 apothecas, described filling apparatus comprises the filling piston and is located at below the described filling piston outstanding and be used for ejecting or the filling push rod of the described sealing-plug of bursting, diaphragm seal or thin-walled.
Preferably, also be provided with the filling push rod above the described filling piston.
Preferably, be provided with xsect on the described filling push rod greater than the filling handle of filling push rod.
Preferably, described second cup upper end is fixedly connected or one-body molded filling push rod protective cover arranged.
Preferably, described filling push rod protective cover is made of the part extension of the xsect of described second cup.
Preferably, the cock body of described filling piston is provided with at least two O-ring seals.
Preferably, described first cup is provided with at least one transparent window.
Preferably, described first cup is provided with two corresponding transparent planes.
The invention has the beneficial effects as follows, first cup and second cup of separable connection are provided, can quantitatively the reagent sealing be placed in reactant 2 apothecas of second cup in advance, this product can be produced in batches, when doing test, only need second cup is taken off from first cup, then material to be checked is quantitatively put into reactant 1 apotheca of first cup, again second cup and first cup are connected, promote filling apparatus, the reagent in second cup is injected first cup, finish detection reaction, also can place the reactant that needs in first cup as required in advance, this device makes whole convenient test quick, has improved work efficiency greatly.
Description of drawings
Fig. 1 is biochemical reaction integrated device synoptic diagram;
Fig. 2 is biochemical reaction integrated device sectional view;
Fig. 3 is the filling apparatus structural representation;
Fig. 4 is the second cup synoptic diagram;
Fig. 5 is the first cup synoptic diagram.
Embodiment
Below in conjunction with specific embodiment, further set forth the present invention.Should be understood that these embodiment only to be used for explanation the present invention and be not used in and limit the scope of the invention.Should be understood that in addition after having read content of the present invention, those skilled in the art can make various changes or modifications the present invention, these equivalent form of values fall within the attached claims restricted portion of the application equally.
Embodiment 1,
Arrive shown in Figure 5 as Fig. 1, a kind of biochemical reaction integrated device, comprise first cup 1 and second cup 21, described first cup 1 is provided with reactant 1 apotheca 11 that holds reactive material, and described second cup 21 is provided with reactant 2 apothecas 25 that hold reactive material.
The upper end of described second cup, 21 lower ends and described first cup 1 is provided with the connecting portion of mutual coupling, and separable being serially connected, and the wall of cup of the bottom of described second cup 21 and first cup 1 forms reactant 1 apotheca 11 of sealing.This connecting portion is in the present embodiment diagram, the bottom cup that is second cup 21 is sheathed in the cavity on first cup, 1 top, the two seals coupling mutually, the mode of sealing can be the mode by traditional glass material frosted, or the increase rubber seal ring, and take the screw thread modes such as adding sealing ring that spins.Except this connected mode, also can be the top cover of first cup 1 if be rotatably connected in the cavity that the bottom of second cup 21 is provided with, the form of a bottle cap is made in the bottom that is about to second cup 21, is connected with first cup, 1 coupling, on earth the purpose of connection and sealed reaction thing 1 apotheca 11.
The bottom of described second cup 21 is provided with a through hole 23, and described through hole is provided with diaphragm seal 24.Sealing film 24 makes reactant 2 apothecas 25 and reactant 1 apotheca 11 sealed separation, before test, the reactant that stores in two apothecas is isolated and is placed, when needs are tested, destroy sealing film 24, be that reactant in reactant 2 apothecas 25 enters in reactant 1 apotheca 11, react with wherein reactant, finish the reaction test experiment.
In order to realize destroying above-mentioned diaphragm seal 24 easily, also be arranged with filling apparatus in described reactant 2 apothecas 25, described filling apparatus comprises filling piston 33 and is located at below the described filling piston 33 outstanding and be used for ejecting or the filling push rod 34 of the described diaphragm seal 24 of bursting.
Can quantitatively the reagent sealing be placed in reactant 2 apothecas 25 of second cup 21 in advance, this product can be produced in batches, when doing test, only need second cup 21 is taken off from first cup 1, then material to be checked is quantitatively put into reactant 1 apotheca 11 of first cup 1, again second cup 21 and first cup 1 are connected, promote the filling piston 33 of filling apparatus, make filling push rod 34 bursting diaphragm seals 24, with second cup, the reagent in 2 injects first cup 1, finish detection reaction, also can place the reactant that needs in first cup 1 as required in advance, this device makes whole convenient test quick, has improved work efficiency greatly.
Embodiment 2,
All the other are identical with embodiment 1, difference is, the described filling piston 33 of promotion for convenience, on described filling piston 33, also be provided with filling push rod 32, these filling push rod 32 bodies are outside second cup 21, conveniently press it, and promote filling piston 33 and move downward, finish filling work.
Embodiment 3,
All the other are identical with embodiment 2, and difference is that described filling push rod 32 upper ends are provided with xsect greater than the filling handle 31 of filling push rod 32.Can operate with thumb easily like this.
Embodiment 4,
All the other are identical with embodiment 2 or embodiment 3, and difference is, and are fixedly connected or one-body molded filling push rod protective cover 22 arranged in the upper end of described second cup 21.Described filling push rod protective cover 22 is made of the part extension of the xsect of described second cup.Like this filling push rod 32 and filling handle 31 are played a protective effect; in the Product transport process; and in the operating process, can avoid because mistake is bumped filling push rod 32 or filling handle 31, and cause fractureing, leak or stave the accident of diaphragm seal 24 etc.
Embodiment 5,
All the other are identical with embodiment 1, embodiment 2, embodiment 3 or embodiment 4, and difference is that the cock body of described filling piston is provided with at least two O-ring seals.Increase the tightness of reactant 2 apothecas like this, be conducive to the preservation of reactant wherein.
In above-described embodiment, for the ease of the observing response situation, be provided with a transparent window 12 at described first cup 1.Also can need as required, set a plurality of transparent windows, perhaps directly make cup with transparent material.
In addition, for the ease of colorimetric experimental requirements or other experimental requirements, described first cup 1 is provided with two corresponding transparent planes, as shown in Figure 5, is convenient to associative operation.
In above-described embodiment, the shape of first cup 1 and second cup 21 can be cylindrical, square column type, rectangle cylindricality, polygon cylindricality or other arbitrary shapes.
The invention has the beneficial effects as follows, first cup and second cup of separable connection are provided, can quantitatively the reagent sealing be placed in reactant 2 apothecas of second cup in advance, this product can be produced in batches, when doing test, only need second cup is taken off from first cup, then material to be checked is quantitatively put into reactant 1 apotheca of first cup, again second cup and first cup are connected, promote filling apparatus, the reagent in second cup is injected first cup, finish detection reaction, also can place the reactant that needs in first cup as required in advance, this device makes whole convenient test quick, has improved work efficiency greatly.
More than be the description to the embodiment of the invention, by the above-mentioned explanation to the disclosed embodiments, make this area professional and technical personnel can realize or use the present invention.Multiple modification to these embodiment will be apparent concerning those skilled in the art, and defined General Principle can realize under the situation that does not break away from the spirit or scope of the present invention in other embodiments herein.Therefore, the present invention will can not be restricted to these embodiment shown in this article, but will meet the wideest scope consistent with principle disclosed herein and features of novelty.

Claims (8)

1. a biochemical reaction integrated device is characterized in that, comprises first cup and second cup, and described first cup is provided with reactant 1 apotheca that holds reactive material, and described second cup is provided with reactant 2 apothecas that hold reactive material,
The upper end of the described second cup lower end and described first cup is provided with the connecting portion of mutual coupling, and separable being serially connected, and the wall of cup of the bottom of described second cup and first cup forms reactant 1 apotheca of sealing,
The bottom of described second cup is provided with a through hole, and described through hole is provided with sealing-plug or diaphragm seal, or one-body molded thin-walled is arranged,
Also be arranged with filling apparatus in described reactant 2 apothecas, described filling apparatus comprises the filling piston and is located at below the described filling piston outstanding and be used for ejecting or the filling push rod of the described sealing-plug of bursting, diaphragm seal or thin-walled.
2. biochemical reaction integrated device as claimed in claim 1 is characterized in that, also is provided with the filling push rod above the described filling piston.
3. biochemical reaction integrated device as claimed in claim 2 is characterized in that, described filling push rod upper end is provided with xsect greater than the filling handle of filling push rod.
4. as claim 2 or 3 described biochemical reaction integrated devices, it is characterized in that described second cup upper end is fixedly connected or one-body molded filling push rod protective cover arranged.
5. biochemical reaction integrated device as claimed in claim 4 is characterized in that, described filling push rod protective cover is made of the part extension of the xsect of described second cup.
6. biochemical reaction integrated device as claimed in claim 4 is characterized in that, the cock body of described filling piston is provided with at least two O-ring seals.
7. biochemical reaction integrated device as claimed in claim 4 is characterized in that, described first cup is provided with at least one transparent window.
8. biochemical reaction integrated device as claimed in claim 4 is characterized in that, described first cup is provided with two corresponding transparent planes.
CN201110443041.4A 2011-12-27 2011-12-27 A kind of biochemical reaction integrated device Active CN103185769B (en)

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CN103185769A true CN103185769A (en) 2013-07-03
CN103185769B CN103185769B (en) 2015-11-04

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105548020A (en) * 2015-12-09 2016-05-04 苏州德沃生物技术有限公司 Full-automatic multichannel biochemical detector and detection method thereof
CN105935607A (en) * 2016-06-28 2016-09-14 江阴市正中科教器材有限公司 Quantitative filling test tube
CN105935605A (en) * 2016-06-28 2016-09-14 江阴市正中科教器材有限公司 Glass test tube capable of accelerating reaction speed
CN108216888A (en) * 2018-04-02 2018-06-29 东莞东阳光科研发有限公司 A kind of liquid reagent storage and release device and reaction system

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CN1842299A (en) * 2003-08-25 2006-10-04 香港澳维有限公司 Biological specimen collection and analysis system
CN201476980U (en) * 2009-08-20 2010-05-19 苏州浦隆生物有限公司 Device for sampling and testing
CN101835428A (en) * 2007-10-23 2010-09-15 贝克顿·迪金森公司 Tissue container for molecular and histology diagnostics incorporating a breakable membrane
CN101896276A (en) * 2007-11-28 2010-11-24 智能管公司 Devices, systems and methods for the collection, stimulation, stabilization, and analysis of a biological sample
CN101909758A (en) * 2007-11-20 2010-12-08 3M创新有限公司 Sample preparation container and method
CN201845009U (en) * 2010-11-11 2011-05-25 郝书顺 Integrated quantitative sampling reagent adding device
CN202383123U (en) * 2011-12-27 2012-08-15 苏州德沃生物技术有限公司 Biochemical reaction integral device

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1842299A (en) * 2003-08-25 2006-10-04 香港澳维有限公司 Biological specimen collection and analysis system
WO2005050167A2 (en) * 2003-11-14 2005-06-02 Oakville Hong Kong Co., Limited Rapid sample collection and analysis device
CN101835428A (en) * 2007-10-23 2010-09-15 贝克顿·迪金森公司 Tissue container for molecular and histology diagnostics incorporating a breakable membrane
CN101909758A (en) * 2007-11-20 2010-12-08 3M创新有限公司 Sample preparation container and method
CN101896276A (en) * 2007-11-28 2010-11-24 智能管公司 Devices, systems and methods for the collection, stimulation, stabilization, and analysis of a biological sample
CN201476980U (en) * 2009-08-20 2010-05-19 苏州浦隆生物有限公司 Device for sampling and testing
CN201845009U (en) * 2010-11-11 2011-05-25 郝书顺 Integrated quantitative sampling reagent adding device
CN202383123U (en) * 2011-12-27 2012-08-15 苏州德沃生物技术有限公司 Biochemical reaction integral device

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105548020A (en) * 2015-12-09 2016-05-04 苏州德沃生物技术有限公司 Full-automatic multichannel biochemical detector and detection method thereof
CN105548020B (en) * 2015-12-09 2018-09-18 苏州德沃生物技术有限公司 Fully-automatic multi-channel biochemical detection device and its detection method
CN105935607A (en) * 2016-06-28 2016-09-14 江阴市正中科教器材有限公司 Quantitative filling test tube
CN105935605A (en) * 2016-06-28 2016-09-14 江阴市正中科教器材有限公司 Glass test tube capable of accelerating reaction speed
CN108216888A (en) * 2018-04-02 2018-06-29 东莞东阳光科研发有限公司 A kind of liquid reagent storage and release device and reaction system

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