CN103167881B - 用于抑制hiv传播的方法和组合物 - Google Patents
用于抑制hiv传播的方法和组合物 Download PDFInfo
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- CN103167881B CN103167881B CN201180028300.5A CN201180028300A CN103167881B CN 103167881 B CN103167881 B CN 103167881B CN 201180028300 A CN201180028300 A CN 201180028300A CN 103167881 B CN103167881 B CN 103167881B
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- 210000002784 stomach Anatomy 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 239000002344 surface layer Substances 0.000 description 1
- 229940054565 sustiva Drugs 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 239000006068 taste-masking agent Substances 0.000 description 1
- 229960004556 tenofovir Drugs 0.000 description 1
- VCMJCVGFSROFHV-WZGZYPNHSA-N tenofovir disoproxil fumarate Chemical compound OC(=O)\C=C\C(O)=O.N1=CN=C2N(C[C@@H](C)OCP(=O)(OCOC(=O)OC(C)C)OCOC(=O)OC(C)C)C=NC2=C1N VCMJCVGFSROFHV-WZGZYPNHSA-N 0.000 description 1
- MHXBHWLGRWOABW-UHFFFAOYSA-N tetradecyl octadecanoate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OCCCCCCCCCCCCCC MHXBHWLGRWOABW-UHFFFAOYSA-N 0.000 description 1
- 239000004416 thermosoftening plastic Substances 0.000 description 1
- 239000006208 topical dosage form Substances 0.000 description 1
- 229940042129 topical gel Drugs 0.000 description 1
- 231100000041 toxicology testing Toxicity 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 108700012359 toxins Proteins 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000001052 transient effect Effects 0.000 description 1
- 230000014599 transmission of virus Effects 0.000 description 1
- 230000032258 transport Effects 0.000 description 1
- 230000010415 tropism Effects 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 229940098802 viramune Drugs 0.000 description 1
- 230000003253 viricidal effect Effects 0.000 description 1
- 229940045860 white wax Drugs 0.000 description 1
- 229940087450 zerit Drugs 0.000 description 1
- 229940052255 ziagen Drugs 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1036—Retroviridae, e.g. leukemia viruses
- C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/04—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from milk
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
- C07K2317/12—Immunoglobulins specific features characterized by their source of isolation or production isolated from milk
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- AIDS & HIV (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US32239910P | 2010-04-09 | 2010-04-09 | |
| US61/322399 | 2010-04-09 | ||
| US61/322,399 | 2010-04-09 | ||
| PCT/AU2011/000407 WO2011123900A1 (en) | 2010-04-09 | 2011-04-11 | Methods and compositions for inhibiting hiv transmission |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103167881A CN103167881A (zh) | 2013-06-19 |
| CN103167881B true CN103167881B (zh) | 2017-06-16 |
Family
ID=44761932
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201180028300.5A Expired - Fee Related CN103167881B (zh) | 2010-04-09 | 2011-04-11 | 用于抑制hiv传播的方法和组合物 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20130022619A1 (enExample) |
| EP (1) | EP2555798B1 (enExample) |
| JP (1) | JP6026402B2 (enExample) |
| CN (1) | CN103167881B (enExample) |
| AP (1) | AP3469A (enExample) |
| AU (2) | AU2011238431B2 (enExample) |
| BR (1) | BR112012025678A2 (enExample) |
| CA (1) | CA2795853A1 (enExample) |
| MX (1) | MX343505B (enExample) |
| RU (1) | RU2594249C2 (enExample) |
| WO (1) | WO2011123900A1 (enExample) |
| ZA (1) | ZA201207790B (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3049524A4 (en) * | 2013-09-27 | 2017-06-14 | Duke University | Hiv-1 mother-to-child transmission correlates of protection and vaccine |
| CN103736100B (zh) * | 2013-12-25 | 2017-06-09 | 南方医科大学 | 预防hiv性传播的杀微生物剂酸酐修饰抗sevi多克隆抗体 |
| PH12018500645B1 (en) * | 2015-09-24 | 2022-10-21 | Abvitro Llc | Hiv antibody compositions and methods of use |
| WO2017062070A1 (en) * | 2015-10-07 | 2017-04-13 | Eca Medical Instruments | Gearless compact torque drive |
| US10973679B2 (en) * | 2016-02-12 | 2021-04-13 | Adam Arreola | STD detecting condom |
| AU2021289612A1 (en) * | 2020-06-10 | 2023-01-19 | The University Of Melbourne | HIV-1 antibodies |
| EP4337689A1 (en) | 2021-05-12 | 2024-03-20 | Applied Biomedical Science Institute | Binding polypeptides against sars cov-2 and uses thereof |
| IL308087A (en) | 2021-05-12 | 2023-12-01 | Applied Biomedical Science Inst | Methods for the screening and expression of disulfide-bonded polypeptides |
| JP7421610B1 (ja) | 2022-08-18 | 2024-01-24 | 株式会社マーベラス | ゲーム装置 |
| AU2023379740A1 (en) | 2022-11-16 | 2025-05-29 | Applied Biomedical Science Institute | Fusion polypeptides and binding peptides and methods for producing and using same |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008063331A2 (en) * | 2006-10-23 | 2008-05-29 | Progenics Pharmaceuticals, Inc. | Modified gp140 envelope polypeptides of hiv-1 isolates, compositions, stabilized trimeric complexes, and uses thereof |
| WO2009058989A1 (en) * | 2007-10-30 | 2009-05-07 | International Aids Vaccine Initiative | Antigen-antibody complexes as hiv-1 vaccines |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6039957A (en) * | 1993-12-10 | 2000-03-21 | United States Of America, As Represented By The Department Of Health And Human Services | Oligomeric HIV-1 envelope glycoproteins |
| ATE429518T1 (de) * | 1999-06-24 | 2009-05-15 | Univ Johns Hopkins | Zusammensetzungen und methoden zur vorbeugung transepithelialer übertragung von hiv |
| CN101428006A (zh) * | 2000-09-28 | 2009-05-13 | 诺华疫苗和诊断公司 | 微粒体组合物及其生产方法 |
| CA2739905A1 (en) * | 2008-10-30 | 2010-08-26 | Dana-Farber Cancer Institute | Mimotopes of hiv env |
-
2011
- 2011-04-11 US US13/639,831 patent/US20130022619A1/en not_active Abandoned
- 2011-04-11 CN CN201180028300.5A patent/CN103167881B/zh not_active Expired - Fee Related
- 2011-04-11 JP JP2013502959A patent/JP6026402B2/ja not_active Expired - Fee Related
- 2011-04-11 EP EP11764957.4A patent/EP2555798B1/en not_active Not-in-force
- 2011-04-11 AU AU2011238431A patent/AU2011238431B2/en not_active Ceased
- 2011-04-11 BR BR112012025678A patent/BR112012025678A2/pt not_active Application Discontinuation
- 2011-04-11 AP AP2012006519A patent/AP3469A/xx active
- 2011-04-11 CA CA2795853A patent/CA2795853A1/en not_active Abandoned
- 2011-04-11 WO PCT/AU2011/000407 patent/WO2011123900A1/en not_active Ceased
- 2011-04-11 RU RU2012142999/15A patent/RU2594249C2/ru not_active IP Right Cessation
- 2011-04-11 MX MX2012011574A patent/MX343505B/es active IP Right Grant
-
2012
- 2012-10-17 ZA ZA2012/07790A patent/ZA201207790B/en unknown
-
2017
- 2017-11-22 AU AU2017265055A patent/AU2017265055A1/en not_active Abandoned
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008063331A2 (en) * | 2006-10-23 | 2008-05-29 | Progenics Pharmaceuticals, Inc. | Modified gp140 envelope polypeptides of hiv-1 isolates, compositions, stabilized trimeric complexes, and uses thereof |
| WO2009058989A1 (en) * | 2007-10-30 | 2009-05-07 | International Aids Vaccine Initiative | Antigen-antibody complexes as hiv-1 vaccines |
Non-Patent Citations (2)
| Title |
|---|
| Extensively cross-reactive anti-HIV-1 neutralizing antibodies induced by gp140 immunization;Zhang P.F. et al.;《PNAS》;20070612;第104卷(第24期);摘要，结果和讨论部分，图1-3 * |
| P13-03. Neutralizing antibody to HIV-1 Env from hyperimmune bovine colostrum as a mucosal microbicide strategy for preventing virus transmission;Kramski M et al.;《Retrovirology》;20091022;第6卷(第3期);摘要，方法，结果和讨论部分 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2555798A1 (en) | 2013-02-13 |
| JP2013523783A (ja) | 2013-06-17 |
| AU2011238431B2 (en) | 2016-10-06 |
| MX343505B (es) | 2016-11-04 |
| CN103167881A (zh) | 2013-06-19 |
| ZA201207790B (en) | 2013-06-26 |
| BR112012025678A2 (pt) | 2017-07-18 |
| WO2011123900A1 (en) | 2011-10-13 |
| RU2594249C2 (ru) | 2016-08-10 |
| JP6026402B2 (ja) | 2016-11-16 |
| AP3469A (en) | 2015-11-30 |
| MX2012011574A (es) | 2013-03-05 |
| EP2555798A4 (en) | 2013-11-20 |
| CA2795853A1 (en) | 2011-10-13 |
| US20130022619A1 (en) | 2013-01-24 |
| RU2012142999A (ru) | 2014-05-20 |
| AU2011238431A1 (en) | 2012-11-08 |
| AU2017265055A1 (en) | 2019-06-06 |
| AP2012006519A0 (en) | 2012-10-31 |
| EP2555798B1 (en) | 2016-06-22 |
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Effective date of registration: 20170511 Address after: Victoria, Australia Applicant after: Immuron Ltd. Address before: Victoria, Australia Applicant before: Rose Technology Co.,Ltd. Effective date of registration: 20170511 Address after: Victoria, Australia Applicant after: Rose Technology Co.,Ltd. Address before: Victoria, Australia Applicant before: Kramski Marit Applicant before: Center Robert John Applicant before: D. F. Purcell Effective date of registration: 20170511 Address after: Victoria, Australia Applicant after: Kramski Marit Applicant after: Center Robert John Applicant after: D. F. Purcell Address before: Australia Melbourne Applicant before: THE University OF MELBOURNE Effective date of registration: 20170511 Address after: Australia Melbourne Applicant after: THE University OF MELBOURNE Address before: Victoria, Australia Applicant before: Immuron Ltd. |
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