CN103156971A - Medicine used for controlling senile dementia - Google Patents

Medicine used for controlling senile dementia Download PDF

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Publication number
CN103156971A
CN103156971A CN 201110410766 CN201110410766A CN103156971A CN 103156971 A CN103156971 A CN 103156971A CN 201110410766 CN201110410766 CN 201110410766 CN 201110410766 A CN201110410766 A CN 201110410766A CN 103156971 A CN103156971 A CN 103156971A
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medicine
radix
senile dementia
raw materials
present
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CN 201110410766
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陈冠卿
陈洪涛
陈洪波
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陈冠卿
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Abstract

The invention relates to a medicine used for controlling senile dementia. The invention belongs to the technical field of traditional Chinese medicine preparation. The medicine is mainly composed of 20 raw materials such as prepared rehmannia root, tatarinow sweetflag rhizome, thinleaf milkwort root, sharpleaf uncaria stem with hooks, golden thread, musk, borneol, lucid ganoderma, and suffrutescent flueggea herb. The medicine has the functions of kidney nourishing, heart benefiting, blood circulation activating, stasis removing, essence replenishing, refreshing, brain benefiting, and resuscitating. The medicine has a good controlling effect against senile dementia. The medicine is easy to take and to popularize.

Description

A kind of medicine of preventing and treating alzheimer disease
Affiliated technical field
The invention belongs to the Chinese medicine preparation technical field.
Background technology
Alzheimer disease is a kind of disease of serious harm middle-aged and elderly people, mostly occur in the geratic period, as the male after 65 years old, the women at 55 years old with sequela.Alzheimer disease generally shows the organic pathological changes of brain, sign and mental symptom aspect.As the ventricles of the brain enlarge, brain has atrophy in various degree, and the aging performance of other organ is arranged on sign, as senile, the dedentition of turning white, skin senile plaque, hard of hearing, instability of gait etc.Mental symptom has personality change, emotional lability, the carrying out property hypophrenia etc.Can be absorbed in dull-witted state when serious, even the name of oneself, age all can not answer, and daily life can not be taken care of oneself.In addition, the dementia that also has cerebral arteriosclerosis to cause.Alzheimer disease is a kind of serious difficult disease.Also there is no at present special effective Therapeutic Method both at home and abroad.
Summary of the invention
In order to overcome the deficiencies in the prior art, the invention provides a kind of medicine of new treatment alzheimer disease.The present invention has the kidney invigorating the benefit heart, blood circulation promoting and blood stasis dispelling, fill out marrow puts forth energy the effect of god, consciousness-restoring and orifice-opening.Treatment to alzheimer disease can reach determined curative effect, have no side effect, takes purpose easy, easy popularization.
The technical scheme that adopts that the present invention solves its technical problem is:
The present invention is comprised of Radix Rehmanniae Preparata, Rhizoma Acori Graminei, Radix Polygalae, Fructus Lycii, Ramulus Uncariae Cum Uncis, Rhizoma Coptidis, Cortex Phellodendri, Radix Scutellariae, Fructus Gardeniae, Radix Ginseng, Poria, the Rhizoma Pinelliae, semen juglandis, Moschus, Borneolum Syntheticum, Radix Notoginseng, Hirudo, Carapax et Plastrum Testudinis, Ganoderma lucidum seu Japonicum, Cacumen Securinegae Suffruticosae two Ten Herbs.
In preparation of the present invention about ingredient major function and preparation.
Radix Rehmanniae Preparata in the present invention, nature and flavor are sweet, little hardship, tepor.Contain mannitol, glucose, alkaloid, fatty acid, vitamin A, rehmanin etc.Enriching yin and nourishing kidney, tonifying blood and regulating menstruation.Cure mainly deficiency of YIN insufficiency of blood, the damage of essence strain, the soreness of waist is dizzy, deafness, menoxenia, metrorrhagia, early whitening of beard and hair.
Rhizoma Acori Graminei in the present invention, nature and flavor are hot, warm.Contain volatile oil, tannin, starch, palmitic acid palm fibre acid etc.The loose wind that reduces phlegm, a surname's air to open key, detoxifcation parasite killing.Cure mainly demented infantile convulsion, forgetful dreaminess, anemofrigid-damp arthralgia, fasting dysentery, external treatment carbuncle, eczema.
Radix Polygalae in the present invention, nature and flavor are bitter, suffering, temperature.Contain multiple triterpenoid saponin, polygalytol, fatty oil, resin etc.Intelligence promoting and the mind tranquilizing, loose strongly fragrant eliminating phlegm, subduing inflammation.
Fructus Lycii in the present invention, nature and flavor are sweet, hot.Contain betanin, carotene, riboflavin, fatty oil, nicotinic acid, vitamin A, C.The nourishing kidney controlling nocturnal emission with astringent drugs, nourishing the liver to improve visual acuity.Cure mainly the hepatic and renal YIN deficiency, soreness of the waist and knees, the many tears of blurred vision, cough due to consumptive disease, the seminal emission of quenching one's thirst.
Ramulus Uncariae Cum Uncis in the present invention, nature and flavor are sweet, and are cold.Contain the multiple alkaloids such as Ramulus Uncariae cum Uncis alkali, isorhynchophylline.Heat clearing away relieves dizziness, high fever, infantile convulsions, epilepsy, etc., and is relieving convulsion.Cure mainly the vertigo, pediatric epilepsy scared, spasm.
Rhizoma Coptidis in the present invention, nature and flavor are bitter, and are cold.Contain berberine, 13-methyl-.psi.-coptisine., the multiple alkaloid such as palmatine.Pathogenic fire purging dampness, the relieving restlessness detoxifcation.Cure mainly hotness vexed, feeling of fullness is quenched one's thirst, hematodiarrhoea stomachache, tenesmus, conjunctival congestion and swelling pain, aphtha.
Cortex Phellodendri in the present invention, nature and flavor are bitter, and are cold.Contain berberine, phellodendrine, the multiple alkaloid such as Palmic acid and fatty oil, obacunone, phlegmatic temperament, sterol, the compositions such as lipid.Let out fire mutually, except damp and hot, cure mainly aphtha of the mouth and tongue, conjunctival congestion tinnitus, hematodiarrhoea diarrhea, osteopyrexia and fever.
Radix Scutellariae in the present invention, nature and flavor are bitter, and are cold.Contain baicalin, neobaicalein, glucuronic acid, enzyme etc.Clearing away damp-heat, purte the white, antiabortive detoxifcation.Cure mainly jaundice due to damp-heat, cough due to lung-heat, ulcer sores, frequent fetal movement.
Fructus Gardeniae in the present invention, nature and flavor are bitter, and are cold.Contain gardenoside, flavochrome, amaroid, quintessence oil, mannitol, choline, carotene, sorbitol, micro-crocetin, pectin, tannin etc.Heat clearing away, diuresis, removing heat from blood.Treatment by oral administration of medicines calentura dysphoria and insomnia, thirsty, pharyngalgia, conjunctival congestion, jaundice, five types of stranguria is spitted blood, epistaxis, dysentery is had blood in stool.The external treatment traumatic injury is dampened, and swells and ache.
Radix Ginseng in the present invention, nature and flavor are sweet, hardship, tepor.Contain the ginsenoside, volatile oil, panax acid, glycocide etc.Invigorating QI to relieve exhaustion, promoting the production of body fluid and inducing sedation of the mind.Cure mainly the vigour weakness, inappetence, cold extremities due to sweating, deficiency of body fluid, the deficiency of the lung is breathed with cough, and palpitates with fear forgetful.
Poria in the present invention, nature and flavor are sweet, and are light, flat.Contain pachymic acid, ergosterol, choline, histidine, protein, lecithin, fat etc.Eliminating dampness and diuresis, tranquilizing mind, strengthening the spleen stomach.Cure mainly spleen-asthenia with excessive damp, edema distension, phlegm retention cough with dyspnea, dirty the having loose bowels of vomitting, dysuria.
The Rhizoma Pinelliae in the present invention, nature and flavor are hot, and temperature is poisonous.Contain glucose, pungent alcohols, three note enols, trace volatile oil, Palmic acid, alkaloid, phlegmatic temperament, starch, oleic acid, stearic acid, core of Caulis et Folium Lini acid etc.Drying dampness to eliminate phlegm, stopping nausea and vomiting by lowering the adverse flow of QI.Cure mainly the phlegm-damp diseases caused by retention of fluid, chest and diaphragm distension, vomiting cough with asthma, dizziness headache.
Semen juglandis in the present invention, nature and flavor are sweet, temperature.The kidney invigorating, warming the lung, intestine moistening, supplementing the brain brain-strengthening.Cure mainly the pain in the lumbar region flaccidity of the lower limbs, loins heavily falls, and works the difficulty of being confined, and deficiency and coldness is breathed with cough, chronic cough of deficiency lung, dryness of the intestine constipation.
Moschus in the present invention, nature and flavor are hot, temperature.Contain volatile oil, in oil, main component is muscone, and fatty, resin, protein, inorganic salt etc.The analepsia of having one's ideas straightened out, blood circulation promoting and dispersing pathogen accumulation, the lower tire of hastening parturition.Cure mainly apoplexy, syncope due to accumulation of phlegm, infantile convulsion, traumatic injury, lump in the abdomen, the trusted subordinate aches cruelly, carbuncle, skin ulcer is swollen etc.
Borneolum Syntheticum in the present invention, nature and flavor are hot, hardship.Contain dextro Borneolum Syntheticum.The open hole powder fire, eyesight-improving and pain-alleviating.Cure mainly the apoplexy lockjaw, infantile convulsion expectorant fan.
Radix Notoginseng in the present invention, nature and flavor are sweet, temperature, bitter in the mouth.Contain multiple triterpenoid saponin (arasaponin first, the second grade).The dissipating blood stasis hemostasis, subduing swelling and relieving pain.Cure mainly various hemorrhage, traumatic injury, carbuncle pain, puerperal blood faints, blood stasis abdomen pain etc.
Hirudo in the present invention, nature and flavor are salty, and hardship is flat.Contain protein, hirudin, heparin, antithromboxin etc.Removing blood stasis, removing blood stasis stimulates the menstrual flow.Cure mainly women's amenorrhea, blood-stasis internal-depression, lump in the abdomen, traumatic injury, conjunctival congestion is swollen, nebula.
Carapax et Plastrum Testudinis in the present invention, nature and flavor are sweet, and are salty, flat.Contain colloidality albumen, calcium carbonate and fat etc., nourishing YIN for suppressing the hyperactive YANG, reducing the asthenic fever.Cure mainly deficiency of kidney yin, the hectic fever due to YIN-deficiency consumptive fever, chronic cough, dry mouth and throat, waist lower limb ache, the seminal emission leukorrhagia is spitted blood, epistaxis, the atrophic debility of bones, stirring of wind due to deficiency of YIN, chronic dysentery, chronic malaria, hemorrhoid, children's's chimney does not conform to.
Ganoderma lucidum seu Japonicum in the present invention, nature and flavor are sweet, and are flat.Contain ergosterol, organic acid, polysaccharide, resin, mannitol, alkaloid, lactone, coumarin, water soluble protein and multiple enzyme etc.Nourish strongly, calm the nerves, relieving asthma.Cure mainly dizziness, insomnia, neurasthenia, hypertension, coronary heart disease, hyperlipidemia, hepatitis, chronic bronchitis, pneumosilicosis, asthma, rheumatic arthritis, dyspepsia, asthenia etc.
Cacumen Securinegae Suffruticosae in the present invention, nature and flavor are sweet, and hardship is flat, poisonous.Contain Securinine, securinol A, Cacumen Securinegae Suffruticosae B, dihydrosecurinine and chromocor compound etc.Relaxing muscles and tendons and activating QI and blood in the collateral, kidney tonifying is supporing yang.Cure mainly dizzy, deafness, neurasthenia, lethargy, sexual impotence, facial paralysis, rheumatism pain in the lumbar region, numb limbs and tense tendons, poliomyelitis sequela etc.
Alzheimer disease is brain generation solid lesion and causing.On the traditional Chinese medical science, alzheimer disease is many because of the loss of kidney yin kidney yang, insufficiency of heart-YIN, and flaccidity of the heart-yang, or because of mental confusion due to phlegm, or wither because brains lose.The present invention has the kidney invigorating benefit heart, blood circulation promoting and blood stasis dispelling, and QI invigorating is eliminated the phlegm, and god is put forth energy in replenishing essence, and the effect of consciousness-restoring and orifice-opening is therefore have good effect to alzheimer disease.Take easyly, easily promote.
Beneficial effect in the present invention is: alzheimer disease is had good effect, have no side effect, take easyly, accelerate Rehabilitation, improve patients ' life quality.
The specific embodiment
1, crude drug formula and part by weight: Radix Rehmanniae Preparata 5.80%, Rhizoma Acori Graminei 3.90%, Radix Polygalae 3.90%, Fructus Lycii 4.80%, Ramulus Uncariae Cum Uncis 11.30%, Rhizoma Coptidis 2.00%, Radix Scutellariae 4.80%, Cortex Phellodendri 4.80%, Fructus Gardeniae 4.80%, Radix Ginseng 3.90%, Poria 4.80%, the Rhizoma Pinelliae 3.90%, semen juglandis 9.70%, Moschus 0.35%, Borneolum Syntheticum 2.00%, Radix Notoginseng 4.80%, Hirudo 5.80%, Carapax et Plastrum Testudinis 6.50%, Ganoderma lucidum seu Japonicum 8.35%, Cacumen Securinegae Suffruticosae 3.80%.Above-mentioned raw materials medicine gross weight is than being a hundred per cent.
2, with above crude drug in proportion weighing assort, it is qualified to concoct with the pharmaceutical equipment apparatus, purifies, concentrated, the mix homogeneously post-treatment becomes capsule, tablet, granule, pill, the different dosage forms such as oral liquid are standby.

Claims (1)

1. medicine of preventing and treating alzheimer disease, it is characterized in that crude drug formula and part by weight are Radix Rehmanniae Preparata 5.80%, Rhizoma Acori Graminei 3.90%, Radix Polygalae 3.90%, Fructus Lycii 4.80%, Ramulus Uncariae Cum Uncis 11.30%, Rhizoma Coptidis 2.00%, Radix Scutellariae 4.80%, Cortex Phellodendri 4.80%, Fructus Gardeniae 4.80%, Radix Ginseng 3.90%, Poria 4.80%, the Rhizoma Pinelliae 3.90%, semen juglandis 9.70%, Moschus 0.35%, Borneolum Syntheticum 2.00%, Radix Notoginseng 4.80%, Hirudo 5.80%, Carapax et Plastrum Testudinis 6.50%, Ganoderma lucidum seu Japonicum 8.35%, Cacumen Securinegae Suffruticosae 3.80%, above-mentioned raw materials medicine gross weight is than being a hundred per cent; With the above-mentioned raw materials medicine in proportion weighing assort, with the pharmaceutical equipment apparatus concoct qualified, purify, concentrated, be processed into capsule, tablet, granule, pill, oral liquid different dosage form.
CN 201110410766 2011-12-12 2011-12-12 Medicine used for controlling senile dementia Pending CN103156971A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103767006A (en) * 2013-12-17 2014-05-07 安徽金安康生物科技有限公司 Health-care beverage suitable for old people to drink and preparation method thereof
CN104524160A (en) * 2014-12-10 2015-04-22 常州诺瑞格纳米科技有限公司 Brain-strengthening and blood circulation-promoting health care product
CN106491680A (en) * 2016-12-14 2017-03-15 四川新绿色药业科技发展有限公司 A kind of Chinese medicine composition of prevention or treatment senile dementia and preparation method thereof
CN109010638A (en) * 2018-09-13 2018-12-18 王鹏同 A kind of Chinese medicament aroma agent and preparation method thereof for senile dementia prevention and cure

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103767006A (en) * 2013-12-17 2014-05-07 安徽金安康生物科技有限公司 Health-care beverage suitable for old people to drink and preparation method thereof
CN103767006B (en) * 2013-12-17 2016-01-20 安徽金安康生物科技有限公司 A kind of applicable the elderly drinks health drink and preparation method thereof
CN104524160A (en) * 2014-12-10 2015-04-22 常州诺瑞格纳米科技有限公司 Brain-strengthening and blood circulation-promoting health care product
CN106491680A (en) * 2016-12-14 2017-03-15 四川新绿色药业科技发展有限公司 A kind of Chinese medicine composition of prevention or treatment senile dementia and preparation method thereof
CN106491680B (en) * 2016-12-14 2020-05-22 四川新绿色药业科技发展有限公司 A Chinese medicinal composition for preventing or treating senile dementia, and its preparation method
CN109010638A (en) * 2018-09-13 2018-12-18 王鹏同 A kind of Chinese medicament aroma agent and preparation method thereof for senile dementia prevention and cure

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Application publication date: 20130619