CN103156696A - Self drug supplying system of monkey drug dependence experimental model - Google Patents
Self drug supplying system of monkey drug dependence experimental model Download PDFInfo
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- CN103156696A CN103156696A CN2011104057537A CN201110405753A CN103156696A CN 103156696 A CN103156696 A CN 103156696A CN 2011104057537 A CN2011104057537 A CN 2011104057537A CN 201110405753 A CN201110405753 A CN 201110405753A CN 103156696 A CN103156696 A CN 103156696A
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Abstract
The invention relates to a self drug supplying system of a monkey drug dependence experimental model. The self drug supplying system of the monkey drug dependence experimental model is characterized by at least comprising a box body. A heating unit, a drug supplying unit, a light source and a noise source are arranged in the box body. A camera shooting unit and a displayer unit are connected. The heating unit, the light source and the noise source are respectively connected with a power source through a pull switch in an electrical mode. The drug supplying unit is electrically connected with a control unit. Conditioned reflex details of animals can be conveniently understood at any time when temperature, light rays and noise are mutated.
Description
Technical field
The present invention relates to the self administration system of monkey drug study model, particularly monkey For Drug Discrimination Test model.
Background technology
Zoologizeing in conditioned reflex test, often needing to observe animal is subject under certain external condition effect, which kind of state reaction of animals is, trained reflex temperature, light and noise etc. by the trained reflex research to different animals, not only are conducive to the mankind itself animal and the support of self-sow rule are held, also being conducive to the mankind holds with natural growth rhythm support in mutual, heavy and science near nature, near animal, be mankind's services.
Summary of the invention
The purpose of this invention is to provide a kind of self administration system of monkey For Drug Discrimination Test model, in order to understand at any time the details of animal trained reflex when temperature, light and noise sudden change.
The object of the present invention is achieved like this, the self administration system of monkey For Drug Discrimination Test model, it is characterized in that: comprise at least casing, be placed in heating unit in casing, administration unit, light source and noise source, image unit is electrically connected to display, heating unit, light source are electrically connected to power supply by pullswitch respectively with noise source, and the administration unit is electrically connected to control unit.
Described light source is one group of redness or green indicating lamp.
Described light source is one group of redness and green indicating lamp.
Described noise source is modulating audio frequency circuit and an audio power output circuit, and audio power output circuit is electrically connected to loudspeaker, and modulating audio frequency circuit and audio power output circuit are serially connected in power circuit by pullswitch, and switch is a pullswitch.
Described light source pullswitch is connected in series in the loop that is electrically connected to by light source, power supply.
Described administration unit comprises to medicine-chest and administration spoon, connects for medicine-chest by pipeline with the administration spoon, is connected to valve on pipeline, and valve is electrically connected to control unit.
Described casing is that 750 millimeters of length, width are 900 millimeters, highly are 1800 millimeters.
Described heating unit is heater strip or the heating lamp that is placed in the box perispore layer, heater strip or heating lamp and be electrically connected in series current limiting pipe in series circuit by switch and power supply.
The present invention is equipped with one group of red led and one group of green indicating lamp in device the place ahead, stimulates to reach visual condition.When stimulating, laboratory animal the place ahead of participation has by each 1 group, the switch red, that green rope is controlled, and pulls the rope of different colours by animal, reaches self administration.The research of the mandatory drug-seeking behavior of the animal strengthening effect opposite with two classes, make researcher set up the experimental tool of a whole set of effectively evaluating drug dependence begetting power by experiment.After reward stimulation and certain specific environment were contacted repeatedly, the Rhesus Macacus that participates in experiment just can obtain to award characteristic, namely can bring out in this specific environment the sort of non-conditioned behavior effect that the initial and non-condition award of animal links together.
Description of drawings
The invention will be further described below in conjunction with the embodiment accompanying drawing:
Fig. 1 is embodiment of the present invention structural representation;
Fig. 2 is the control unit schematic diagram.
In figure, 1, casing; 2, heating unit; 3, light source; 4, noise source; 5, image unit; 6, give medicine-chest; 7, administration spoon; 8, chamber door; 9, control unit; 10, pipeline; 11, valve; 12, motor; 13, controller; 14, rectification circuit.
The specific embodiment
As depicted in figs. 1 and 2, the self administration system of monkey For Drug Discrimination Test model comprises casing 1 at least, is placed in heating unit 2 in casing 1, administration unit, light source 3 and noise source 4, heating unit 2, light source 3 and noise source 4 respectively with the electric power generating composition loop, pullswitch is serially connected in the loop.The administration unit comprises to medicine-chest 6 and administration spoon 7, is connected for medicine-chest 6 with the administration spoon and connects by pipeline 10, is connected to valve 11 on pipeline, and valve 11 is electrically connected to control unit 9.There is an image unit to be electrically connected to display outside casing 1 in casing 1.Light source 3 is one group of redness or green indicating lamp.Can be also one group of redness and green indicating lamp.The pullswitch K1 that controls light source 3 is the rope of different colours, pulls the rope of different colours by animal, and one group of red led and one group of green indicating lamp reach visual condition to stimulate.When stimulating, the valve 11 on pipeline is opened, and enters in administration spoon 7 for the pill of medicine-chest 6 from pipeline, completes the selection self administration.
The pullswitch K2 in embodiment 2 control noise sources 4 as different from Example 1, noise source 4 work, noise source is modulating audio frequency circuit and an audio power output circuit, audio power output circuit is electrically connected to loudspeaker, modulating audio frequency circuit and audio power output circuit are serially connected in power circuit by pullswitch, and when stimulating, the valve 11 on pipeline is opened, enter in administration spoon 7 for the pill of medicine-chest 6 from pipeline, complete the selection self administration.
That different with embodiment 2 from embodiment 1 is the pullswitch K3 that embodiment 3 controls heating unit 2, heating unit 2 work, heating unit is heater strip or the heating lamp that is placed in the box perispore layer, heater strip or heating lamp and be electrically connected in series current limiting pipe in series circuit by switch and power supply.Pullswitch K3 pulls, heater strip or heating lamp work, and the temperature of casing 1 raises, and controller 13 is by detected temperatures, and when temperature arrived design temperature, controller 13 was controlled motors 12 and is rotated, and automatically opened chamber door 8 one gaps, regulated temperature.
Casing is that 750 millimeters of length, width are 900 millimeters, highly are 1800 millimeters.
As shown in Figure 2, control unit 9 comprises a valve 11, motor 12, controller 13, Acquisition Circuit and on-off circuit 15, Acquisition Circuit is made of three road stabilivolts and resistance series connection, in the work loop of heating unit 2, light source 3 and noise source 4, be used for to gather the duty of heating unit 2, light source 3 and noise source 4, be connected in series respectively K1, K2 and K3 in on-off circuit 15 in heating unit 2, light source 3 and noise source 4 work loops; Determine by K1, K2 and K3 whether heating unit 2, light source 3 and noise source 4 work loops work.Rectification circuit 14 exchanges 220V and carries out forming DC voltage after rectifying and wave-filtering, the work loop of heating unit 2 in parallel during direct current is pressed, light source 3 work loops and noise source 4 work loops.K1 connects, the dc source anode passes through light source 3, K switch 1 and first via sample circuit to negative terminal, K switch 1 closure, the stabilivolt of first via sample circuit (3V or 5V stabilivolt) work has 3V or 5V output, and output signal is input to an I/O mouth of controller 13, controller 13 receives the signal of telecommunication, by eliminating the switching noise signal, whether work with by-pass valve control 11, whether decision puts into food or medicine by pipeline 10 to administration spoon 7 by the medicine-chest 6 of giving of Fig. 1.Equally, K2 connects, the dc source anode passes through heating unit 2, K switch 2 and the No. the second sample circuit to negative terminal, K switch 2 closures, the stabilivolt of the No. the second sample circuit (3V or 5V stabilivolt) work, 3V or 5V output is arranged, output signal is input to the 2nd I/O mouth of controller 13, and controller 13 receives the signal of telecommunication, by eliminating the switching noise signal, whether work to control motor 12, open chamber door 8 regulating and controlling temperatures.Same again, K3 connects, the dc source anode passes through noise source 4, K switch 3 and Third Road sample circuit to negative terminal, K switch 3 closures, the stabilivolt of Third Road sample circuit (3V or 5V stabilivolt) work, 3V or 5V output is arranged, output signal is input to the 3rd I/O mouth of controller 13, and controller 13 receives the signal of telecommunication, by eliminating the switching noise signal, whether work with by-pass valve control 11, whether decision puts into medicine or food by pipeline 10 to administration spoon 7 by the medicine-chest 6 of giving of Fig. 1.
The present invention is according to the principle of trained reflex, and laboratory animal is mandatory, and to look for medicine capable, makes researcher set up the experimental tool of a whole set of effectively evaluating drug dependence begetting power.After reward stimulation and certain specific environment were contacted repeatedly, the Rhesus Macacus that participates in experiment just can obtain to award characteristic, namely can bring out in this specific environment the sort of non-conditioned behavior effect that the initial and non-condition award of animal links together.
Claims (8)
1. the self administration system of monkey For Drug Discrimination Test model, it is characterized in that: comprise at least casing, be placed in heating unit in casing, administration unit, light source and noise source, image unit is electrically connected to display, heating unit, light source are electrically connected to power supply by pullswitch respectively with noise source, and the administration unit is electrically connected to control unit.
2. the self administration system of monkey For Drug Discrimination Test model according to claim 1, it is characterized in that: described light source is one group of redness or green indicating lamp.
3. the self administration system of monkey For Drug Discrimination Test model according to claim 1, it is characterized in that: described light source is one group of redness and green indicating lamp.
4. the self administration system of monkey For Drug Discrimination Test model according to claim 1, it is characterized in that: described noise source is modulating audio frequency circuit and an audio power output circuit, audio power output circuit is electrically connected to loudspeaker, modulating audio frequency circuit and audio power output circuit are serially connected in power circuit by pullswitch, and switch is a pullswitch.
5. the self administration system of monkey For Drug Discrimination Test model according to claim 1 is characterized in that: described light source pullswitch is connected in series in the loop that is electrically connected to by light source, power supply.
6. the self administration system of monkey For Drug Discrimination Test model according to claim 1, it is characterized in that: described administration unit comprises to medicine-chest and administration spoon, connect for medicine-chest with the administration spoon by pipeline, be connected to valve on pipeline, valve is electrically connected to control unit.
7. the self administration system of monkey For Drug Discrimination Test model according to claim 1 is characterized in that: described casing is that 750 millimeters of length, width are 900 millimeters, highly are 1800 millimeters.
8. the self administration system of monkey For Drug Discrimination Test model according to claim 1, it is characterized in that: described heating unit is heater strip or the heating lamp that is placed in the box perispore layer, heater strip or heating lamp and be electrically connected in series current limiting pipe in series circuit by switch and power supply.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110405753.7A CN103156696B (en) | 2011-12-08 | 2011-12-08 | Self drug supplying system of monkey drug dependence experimental model |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201110405753.7A CN103156696B (en) | 2011-12-08 | 2011-12-08 | Self drug supplying system of monkey drug dependence experimental model |
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| CN103156696A true CN103156696A (en) | 2013-06-19 |
| CN103156696B CN103156696B (en) | 2015-07-01 |
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| CN201110405753.7A Active CN103156696B (en) | 2011-12-08 | 2011-12-08 | Self drug supplying system of monkey drug dependence experimental model |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2655545C1 (en) * | 2017-04-24 | 2018-05-28 | Федеральное государственное бюджетное научное учреждение "Восточно-Сибирский институт медико-экологических исследований" | Method of modeling violations in the organism of laboratory animals caused by noise exposure in the post-containing period |
| CN114667964A (en) * | 2020-12-24 | 2022-06-28 | 中国科学院脑科学与智能技术卓越创新中心 | Method for evaluating primate drug addiction and application |
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2011
- 2011-12-08 CN CN201110405753.7A patent/CN103156696B/en active Active
Patent Citations (5)
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| CN2834160Y (en) * | 2005-09-30 | 2006-11-08 | 中国人民解放军第三军医大学 | Animal positive avoidance reaction training device |
| CN201197305Y (en) * | 2008-04-29 | 2009-02-25 | 西安富康空气净化设备工程有限公司 | Ultra-clean feeding unit |
| CN201492407U (en) * | 2009-05-16 | 2010-06-02 | 大连大学 | Multifunctional respiration environment simulation and sucking type die manufacturing and drug feeding device |
| CN101584585A (en) * | 2009-06-08 | 2009-11-25 | 浙江大学 | Experimental system for the determination of white rat behavior |
| CN202365962U (en) * | 2011-12-08 | 2012-08-08 | 西安富康空气净化设备工程有限公司 | Self drug administration device of monkey drug dependence experiment model |
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| 王建: "损毁腹侧海马下托抑制成瘾大鼠对吗啡的渴求", 《中国优秀硕士学位论文全文数据库》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2655545C1 (en) * | 2017-04-24 | 2018-05-28 | Федеральное государственное бюджетное научное учреждение "Восточно-Сибирский институт медико-экологических исследований" | Method of modeling violations in the organism of laboratory animals caused by noise exposure in the post-containing period |
| CN114667964A (en) * | 2020-12-24 | 2022-06-28 | 中国科学院脑科学与智能技术卓越创新中心 | Method for evaluating primate drug addiction and application |
| CN114667964B (en) * | 2020-12-24 | 2023-11-14 | 中国科学院脑科学与智能技术卓越创新中心 | Method for evaluating addiction of non-human primate medicaments and application thereof |
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| CN103156696B (en) | 2015-07-01 |
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Effective date of registration: 20230817 Address after: No. 11215, 12th Floor, Unit 1, Building 2, Building D, City Gate, Tangyan South Road, High tech Zone, Xi'an City, Shaanxi Province, 710075 Patentee after: Huaxia Fukang Environmental Technology Co.,Ltd. Address before: 710075 Zhongtian International A1908, No. 269 Taibai South Road, Xi'an City, Shaanxi Province Patentee before: XI'AN FUKANG AIR PURIFICATION EQUIPMENT ENGINEERING CO.,LTD. Patentee before: Gao Guodong Patentee before: Li Nan Patentee before: Gao Li Patentee before: Shi Changhong |
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