CN103156022B - 一种银杏叶保健茶及其制备方法 - Google Patents
一种银杏叶保健茶及其制备方法 Download PDFInfo
- Publication number
- CN103156022B CN103156022B CN201110408336.8A CN201110408336A CN103156022B CN 103156022 B CN103156022 B CN 103156022B CN 201110408336 A CN201110408336 A CN 201110408336A CN 103156022 B CN103156022 B CN 103156022B
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- China
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- weight portion
- ginkgo leaf
- niacinamide
- proline
- glycine
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- 235000008100 Ginkgo biloba Nutrition 0.000 title claims abstract description 60
- 235000011201 Ginkgo Nutrition 0.000 title claims abstract description 59
- 238000002360 preparation method Methods 0.000 title claims abstract description 11
- 244000269722 Thea sinensis Species 0.000 title abstract 3
- 244000194101 Ginkgo biloba Species 0.000 title description 3
- 241000218628 Ginkgo Species 0.000 claims abstract description 58
- DHMQDGOQFOQNFH-UHFFFAOYSA-N Glycine Chemical compound NCC(O)=O DHMQDGOQFOQNFH-UHFFFAOYSA-N 0.000 claims description 50
- 241001122767 Theaceae Species 0.000 claims description 31
- 239000004471 Glycine Substances 0.000 claims description 25
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-Proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims description 25
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims description 25
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 claims description 25
- MTCFGRXMJLQNBG-UHFFFAOYSA-N Serine Natural products OCC(N)C(O)=O MTCFGRXMJLQNBG-UHFFFAOYSA-N 0.000 claims description 25
- 229960003966 nicotinamide Drugs 0.000 claims description 25
- 235000005152 nicotinamide Nutrition 0.000 claims description 25
- 239000011570 nicotinamide Substances 0.000 claims description 25
- 239000002994 raw material Substances 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 11
- MTCFGRXMJLQNBG-REOHCLBHSA-N (2S)-2-Amino-3-hydroxypropansäure Chemical compound OC[C@H](N)C(O)=O MTCFGRXMJLQNBG-REOHCLBHSA-N 0.000 claims description 10
- 238000001035 drying Methods 0.000 claims description 10
- 239000006166 lysate Substances 0.000 claims description 9
- 239000008213 purified water Substances 0.000 claims description 9
- 206010013786 Dry skin Diseases 0.000 claims description 8
- 238000000034 method Methods 0.000 claims 1
- 238000004090 dissolution Methods 0.000 abstract description 11
- -1 terpene lactone Chemical class 0.000 abstract description 10
- 229930003935 flavonoid Natural products 0.000 abstract description 9
- 150000002215 flavonoids Chemical class 0.000 abstract description 9
- 235000017173 flavonoids Nutrition 0.000 abstract description 9
- 235000007586 terpenes Nutrition 0.000 abstract description 9
- 239000004480 active ingredient Substances 0.000 abstract description 3
- 150000001413 amino acids Chemical class 0.000 abstract description 2
- 150000001408 amides Chemical class 0.000 abstract 1
- 235000016709 nutrition Nutrition 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 239000000047 product Substances 0.000 description 9
- 239000012467 final product Substances 0.000 description 7
- 239000000203 mixture Substances 0.000 description 6
- 239000000706 filtrate Substances 0.000 description 4
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 description 2
- MOLPUWBMSBJXER-YDGSQGCISA-N bilobalide Chemical compound O([C@H]1OC2=O)C(=O)[C@H](O)[C@@]11[C@@](C(C)(C)C)(O)C[C@H]3[C@@]21CC(=O)O3 MOLPUWBMSBJXER-YDGSQGCISA-N 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- SQFSKOYWJBQGKQ-UHFFFAOYSA-N kaempferide Chemical compound C1=CC(OC)=CC=C1C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1 SQFSKOYWJBQGKQ-UHFFFAOYSA-N 0.000 description 2
- 238000002386 leaching Methods 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 206010002383 Angina Pectoris Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 206010019468 Hemiplegia Diseases 0.000 description 1
- 208000031226 Hyperlipidaemia Diseases 0.000 description 1
- GQODBWLKUWYOFX-UHFFFAOYSA-N Isorhamnetin Natural products C1=C(O)C(C)=CC(C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 GQODBWLKUWYOFX-UHFFFAOYSA-N 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 description 1
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 208000026106 cerebrovascular disease Diseases 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- SQOJOAFXDQDRGF-MMQTXUMRSA-N ginkgolide-b Chemical compound O[C@H]([C@]12[C@H](C(C)(C)C)C[C@H]3OC4=O)C(=O)O[C@H]2O[C@]24[C@@]13[C@@H](O)[C@@H]1OC(=O)[C@@H](C)[C@]21O SQOJOAFXDQDRGF-MMQTXUMRSA-N 0.000 description 1
- 239000008236 heating water Substances 0.000 description 1
- 235000008800 isorhamnetin Nutrition 0.000 description 1
- IZQSVPBOUDKVDZ-UHFFFAOYSA-N isorhamnetin Chemical compound C1=C(O)C(OC)=CC(C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 IZQSVPBOUDKVDZ-UHFFFAOYSA-N 0.000 description 1
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 235000005875 quercetin Nutrition 0.000 description 1
- 229960001285 quercetin Drugs 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 230000001228 trophic effect Effects 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
Description
总黄酮醇苷溶出率* | 萜类内酯溶出率* | |
参照品 | 100% | 100% |
实施例1样品 | 136.4% | 115.5% |
实施例2样品 | 132.7% | 114.8% |
实施例3样品 | 128.6% | 113.4% |
实施例4样品 | 131.9% | 114.6% |
实施例5样品 | 139.2% | 118.3% |
Claims (8)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201110408336.8A CN103156022B (zh) | 2011-12-09 | 2011-12-09 | 一种银杏叶保健茶及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201110408336.8A CN103156022B (zh) | 2011-12-09 | 2011-12-09 | 一种银杏叶保健茶及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN103156022A CN103156022A (zh) | 2013-06-19 |
CN103156022B true CN103156022B (zh) | 2014-12-17 |
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Application Number | Title | Priority Date | Filing Date |
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CN201110408336.8A Active CN103156022B (zh) | 2011-12-09 | 2011-12-09 | 一种银杏叶保健茶及其制备方法 |
Country Status (1)
Country | Link |
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CN (1) | CN103156022B (zh) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1449671A (zh) * | 2002-04-11 | 2003-10-22 | 郝明强 | 一种防辐射保护视力的保健茶及其制备方法 |
CN1472214A (zh) * | 2003-06-27 | 2004-02-04 | 江苏康缘药业股份有限公司 | 一种银杏内酯b的复合物及其制备方法与治疗用途 |
EP1559430A1 (en) * | 2004-01-29 | 2005-08-03 | INDENA S.p.A. | Use of ginkgo complexes for the enhancement of cognitive functions and the alleviation of mental fatigue |
CN101810336A (zh) * | 2010-04-30 | 2010-08-25 | 广东仙乐制药有限公司 | 一种咀嚼性软胶囊及其制备方法 |
-
2011
- 2011-12-09 CN CN201110408336.8A patent/CN103156022B/zh active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1449671A (zh) * | 2002-04-11 | 2003-10-22 | 郝明强 | 一种防辐射保护视力的保健茶及其制备方法 |
CN1472214A (zh) * | 2003-06-27 | 2004-02-04 | 江苏康缘药业股份有限公司 | 一种银杏内酯b的复合物及其制备方法与治疗用途 |
EP1559430A1 (en) * | 2004-01-29 | 2005-08-03 | INDENA S.p.A. | Use of ginkgo complexes for the enhancement of cognitive functions and the alleviation of mental fatigue |
CN101810336A (zh) * | 2010-04-30 | 2010-08-25 | 广东仙乐制药有限公司 | 一种咀嚼性软胶囊及其制备方法 |
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CN103156022A (zh) | 2013-06-19 |
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Owner name: SICHUAN KELUN PHARMACEUTICAL RESEARCH INSTITUTE CO Free format text: FORMER NAME: KELUN PHARMACEUTICAL RESEARCH CO., LTD. |
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CP03 | Change of name, title or address |
Address after: 611138 Sichuan science and Technology Development Zone, Wenjiang District, Chengdu City, Xinhua Road, the central section of the two paragraph Patentee after: SICHUAN KELUN DRUG RESEARCH INSTITUTE CO., LTD. Address before: 610500 Sichuan province Chengdu City satellite city industrial development zone two South Road Patentee before: Kelun Pharmaceutical Research Co., Ltd. |