CN103134843B - 通过电解控制ph梯度以及它们在等电聚焦中的用途 - Google Patents

通过电解控制ph梯度以及它们在等电聚焦中的用途 Download PDF

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Publication number
CN103134843B
CN103134843B CN201210450797.6A CN201210450797A CN103134843B CN 103134843 B CN103134843 B CN 103134843B CN 201210450797 A CN201210450797 A CN 201210450797A CN 103134843 B CN103134843 B CN 103134843B
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proton concentration
volume
environment
proton
pattern
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Expired - Fee Related
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CN103134843A (zh
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U.西万
E.布罗德
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Technion Research and Development Foundation Ltd
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Technion Research and Development Foundation Ltd
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    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00—Treatment of water, waste water, or sewage
    • C02F1/46—Treatment of water, waste water, or sewage by electrochemical methods
    • C02F1/461—Treatment of water, waste water, or sewage by electrochemical methods by electrolysis
    • C02F1/46104—Devices therefor; Their operating or servicing
    • C02F1/46109—Electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G01N27/44795—Isoelectric focusing
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00—Treatment of water, waste water, or sewage
    • C02F1/66—Treatment of water, waste water, or sewage by neutralisation; pH adjustment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44717—Arrangements for investigating the separated zones, e.g. localising zones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44704—Details; Accessories
    • G01N27/44743—Introducing samples
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00—Treatment of water, waste water, or sewage
    • C02F1/46—Treatment of water, waste water, or sewage by electrochemical methods
    • C02F1/461—Treatment of water, waste water, or sewage by electrochemical methods by electrolysis
    • C02F1/46104—Devices therefor; Their operating or servicing
    • C02F1/4618—Devices therefor; Their operating or servicing for producing "ionised" acidic or basic water
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F1/00—Treatment of water, waste water, or sewage
    • C02F1/46—Treatment of water, waste water, or sewage by electrochemical methods
    • C02F1/461—Treatment of water, waste water, or sewage by electrochemical methods by electrolysis
    • C02F1/46104—Devices therefor; Their operating or servicing
    • C02F1/46109—Electrodes
    • C02F2001/46152—Electrodes characterised by the shape or form
    • C02F2001/46157—Perforated or foraminous electrodes
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2201/00—Apparatus for treatment of water, waste water or sewage
    • C02F2201/46—Apparatus for electrochemical processes
    • C02F2201/461—Electrolysis apparatus
    • C02F2201/46105—Details relating to the electrolytic devices
    • C02F2201/46115—Electrolytic cell with membranes or diaphragms
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2201/00—Apparatus for treatment of water, waste water or sewage
    • C02F2201/46—Apparatus for electrochemical processes
    • C02F2201/461—Electrolysis apparatus
    • C02F2201/46105—Details relating to the electrolytic devices
    • C02F2201/4612—Controlling or monitoring
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2201/00—Apparatus for treatment of water, waste water or sewage
    • C02F2201/46—Apparatus for electrochemical processes
    • C02F2201/461—Electrolysis apparatus
    • C02F2201/46105—Details relating to the electrolytic devices
    • C02F2201/4612—Controlling or monitoring
    • C02F2201/46125—Electrical variables
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2201/00—Apparatus for treatment of water, waste water or sewage
    • C02F2201/46—Apparatus for electrochemical processes
    • C02F2201/461—Electrolysis apparatus
    • C02F2201/46105—Details relating to the electrolytic devices
    • C02F2201/4612—Controlling or monitoring
    • C02F2201/46125—Electrical variables
    • C02F2201/4614—Current
    • C—CHEMISTRY; METALLURGY
    • C02—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F—TREATMENT OF WATER, WASTE WATER, SEWAGE, OR SLUDGE
    • C02F2209/00—Controlling or monitoring parameters in water treatment
    • C02F2209/06—Controlling or monitoring parameters in water treatment pH

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Environmental & Geological Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Hydrology & Water Resources (AREA)
  • Water Supply & Treatment (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CN201210450797.6A 2007-08-27 2008-08-26 通过电解控制ph梯度以及它们在等电聚焦中的用途 Expired - Fee Related CN103134843B (zh)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US93569807P 2007-08-27 2007-08-27
US60/935,698 2007-08-27
US60/935698 2007-08-27
US3925708P 2008-03-25 2008-03-25
US61/039257 2008-03-25
US61/039,257 2008-03-25

Related Parent Applications (1)

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CN2008801146906A Division CN101868425B (zh) 2007-08-27 2008-08-26 通过电解控制pH梯度以及它们在等电聚焦中的用途

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CN103134843A CN103134843A (zh) 2013-06-05
CN103134843B true CN103134843B (zh) 2014-11-12

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CN201210450797.6A Expired - Fee Related CN103134843B (zh) 2007-08-27 2008-08-26 通过电解控制ph梯度以及它们在等电聚焦中的用途
CN2008801146906A Expired - Fee Related CN101868425B (zh) 2007-08-27 2008-08-26 通过电解控制pH梯度以及它们在等电聚焦中的用途

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Country Status (8)

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US (2) US9274082B2 (OSRAM)
EP (2) EP2193100B1 (OSRAM)
JP (1) JP5702142B2 (OSRAM)
KR (1) KR20100053672A (OSRAM)
CN (2) CN103134843B (OSRAM)
AU (1) AU2008293381B2 (OSRAM)
CA (1) CA2697649C (OSRAM)
WO (1) WO2009027970A2 (OSRAM)

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EP2193100B1 (en) 2007-08-27 2014-05-07 Technion Research and Development Foundation, Limited pH gradients controlled by electrolysis, and their use in isoelectric focusing
US10107782B2 (en) * 2008-01-25 2018-10-23 ProteinSimple Method to perform limited two dimensional separation of proteins and other biologicals
CN102472724B (zh) * 2009-08-18 2014-08-13 工业研究与发展基金会有限公司 分离分子分析物的方法和装置
US9028664B2 (en) 2009-08-18 2015-05-12 Technion Research & Development Foundation Limited Proton concentration topographies, methods and devices for producing the same
JP5950429B2 (ja) * 2011-05-13 2016-07-13 シャープ株式会社 電気泳動方法、及び電気泳動装置
WO2013067509A1 (en) 2011-11-04 2013-05-10 Bio-Rad Laboratories, Inc. Simultaneous purification of cell components
US9766207B2 (en) 2011-11-04 2017-09-19 Bio-Rad Laboratories, Inc. Affinity methods and compositions employing electronic control of pH
EP2773959B1 (en) 2011-11-04 2019-04-10 Bio-Rad Laboratories, Inc. Protein fractionation based on isoelectric focusing
US20130164860A1 (en) 2011-11-04 2013-06-27 Technion Research & Development Foundation Ltd. Affinity methods and compositions employing electronic control of ph
CN102565171A (zh) * 2012-01-05 2012-07-11 厦门大学 一种用于等电聚焦分离的微流控芯片
WO2013123425A1 (en) 2012-02-15 2013-08-22 Bio-Rad Laboratories, Inc. Electronic control of ph and ionic strength
US9321012B2 (en) 2012-04-04 2016-04-26 Bio-Rad Laboratories, Inc. Electronic protein fractionation
CN104034789A (zh) * 2013-04-02 2014-09-10 上海交通大学 蛋白质等电聚焦电泳的装置
CN106260992B (zh) * 2015-06-09 2020-02-18 海南椰国食品有限公司 一种含有酸性椰果和/或碱性椰果的食品
CN106267304B (zh) * 2015-06-09 2019-10-18 海南光宇生物科技有限公司 具有酸碱性的生物纤维素凝胶膜及由其制备的医用敷料
EP3653121A1 (en) * 2018-11-14 2020-05-20 Koninklijke Philips N.V. Sensor unit, body fluid monitoring device and method for detecting an analyte
CN119470588A (zh) * 2024-11-18 2025-02-18 中国科学院空天信息创新研究院 集成式多种重金属检测微传感器

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CN1549924A (zh) * 2001-07-16 2004-11-24 �����ʸ���˹�ع�˾ 通过等电点分析生物分子的缓冲液的阵列
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CN1558460A (zh) * 2004-02-13 2004-12-29 清华大学 一种质子交换膜燃料电池多元催化剂的制备方法

Also Published As

Publication number Publication date
CN101868425B (zh) 2013-01-02
CN101868425A (zh) 2010-10-20
US20160178578A1 (en) 2016-06-23
US10132776B2 (en) 2018-11-20
EP2559666A3 (en) 2013-04-03
AU2008293381B2 (en) 2012-07-19
WO2009027970A3 (en) 2009-05-14
WO2009027970A2 (en) 2009-03-05
JP5702142B2 (ja) 2015-04-15
CA2697649C (en) 2016-08-09
US20100307920A1 (en) 2010-12-09
AU2008293381A1 (en) 2009-03-05
EP2559666B1 (en) 2014-07-23
CN103134843A (zh) 2013-06-05
JP2010538255A (ja) 2010-12-09
EP2559666A2 (en) 2013-02-20
CA2697649A1 (en) 2009-03-05
EP2193100B1 (en) 2014-05-07
KR20100053672A (ko) 2010-05-20
EP2193100A2 (en) 2010-06-09
US9274082B2 (en) 2016-03-01

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