CN103110898A - Preparation method of traditional Chinese medicine for treating heat toxicity type reflux oesophagitis - Google Patents

Abstract

The invention provides a preparation method of a traditional Chinese medicine for treating heat toxicity type reflux oesophagitis, and belongs to the technical field of preparation methods of traditional Chinese medicines. Currently, ranitidine is generally adopted for treating heat toxicity type reflux oesophagitis, but has a certain side effect. The preparation method is characterized by comprising the following steps of immersing the following traditional Chinese medicines in water, namely starwort root, creeping oxalis, buckthorn, veronicastrum herb, daghestan sweet clover herb, coffee senna seed, common alstonia bark leaf, lophatherum gracile, mungbean, dandelion, red-spotted stonecrop, shortstalk slimptop meadowrue root, breynia fruticosa, small-leaved desmodium, wintercherry, fresh golden thread, uniflower swisscentaury root, olive, taenitis carnosa mett, creeping rostellularia herb, gamboge, potentilla discolor, dutchmanspipe root, radix curcumae, shaddock, immature bitter orange, orange, selfheal, feather cockscomb seed, butterflybush flower, pipewort, scouring rush, chrysanthemum, mint, cicada slough, astragalus and liquorice; and decocting with slow fire to obtain decoction which is the traditional Chinese medicine for treating heat toxicity type reflux oesophagitis. The traditional Chinese medicine has the advantages that adverse reactions, allergy reactions and toxicity reactions caused by Western antimicrobial agents while the traditional Chinese medicine is administrated.

Description

A kind of Chinese medicinal preparation method for the treatment of the heat-toxin type reflux esophagitis

Technical field

The present invention relates to the Chinese medicinal preparation method technical field, more specifically a kind of Chinese medicinal preparation method for the treatment of the heat-toxin type reflux esophagitis.

Background technology

Current treatment heat-toxin type reflux esophagitis, the general employing: 1, ranitidine: 1. contraindication: to this medicine and other H ₂receptor antagonist allergy sufferers, anemia of pregnant woman, women breast-feeding their children, the forbidding of child below 8 years old.2. be cautious use of: liver, renal insufficiency person, acute hematoporphyria person, old people are cautious use of.3. can occur headache, dizzy, weak, obnubilation, mental act extremely, insomnia etc.; The mental symptoms such as disorientation, drowsiness, anxiety, appear in liver, renal insufficiency person and gerontal patient after accidental taking medicine; A small amount of generation blurred vision is arranged; Constipation, diarrhoea occur, feel sick, vomit, suffer from abdominal pain; Erythra can occur, only a few generation erythema multiforme is arranged; Rare arthralgia, myalgia; Rare anaphylactic reaction, show as rubella, vasodilation, heating, bronchospasm, hypotension, anaphylactic shock, chest pain etc.; Life-time service can cause vitamin B ₁₂lack, male breast is womanlike rare; Cause that renal dysfunction etc., quiet notes rear section patient fever sensation of the face sense, dizziness can occur, feel sick, perspiration and gastric irritation.4. this medicine has certain toxicity to liver, therefore, in the administration process, should monitor patient's changes of liver function.When 5. vein gives this medicine, bradycardia can appear.Therefore should be slow during quiet notes, and should make regular check on electrocardiogram in the medication process.6. this medicine has certain inhibitory action to bone marrow, and the moderate leukocyte of reversibility or granulocytopenia can occur small number of patients, also occur thrombocytopenia and autoimmune hemolytic anemia.2, bismuth potassium citrate: 1. contraindication: those who are allergic to this drug, severe renal functional defect, anemia of pregnant woman patient's forbidding.2. be cautious use of: hepatic disfunction person, child, women breast-feeding their children are cautious use of.3. small number of patients can have slight headache, dizziness, insomnia etc.; Erythra can appear in indivedual patients; May distinguish the flavor of with ammonia in mouthful, and tongue, feces can be dyed to black, easily obscure mutually with tarry stool; The symptoms of digestive tract such as indivedual patients can occur feeling sick while taking, diarrhoea, constipation, loss of appetite, diarrhoea.4. long-term, high-dose is taken and may be caused Toxicity of Kidney, causes the reversibility renal failure, and with 10 days in the outbreak, should make regular check on renal function.5. the untoward reaction of the skeleton relevant osteoarthritis of bismuth encephalopathy (HIE) more commonly, the one-sided or both shoulders pain of often take is premonitory symptom.3, omeprazole: 1. contraindication: those who are allergic to this drug, severe renal functional defect person, anemia of pregnant woman, infant patient's forbidding.2. be cautious use of: liver, renal insufficiency person, women breast-feeding their children, gerontal patient should be cautious use of.3. common adverse reactions be diarrhoea, headache, feel sick, stomachache, flatulence and constipation, accidental serum aminotransferase increases, erythra, dizzy, drowsiness, insomnia etc.; Visible chest pain, cardiopalmus, tachycardia or excessively slow, hypertension, periphery edema.Visible microscopic pyuria, albuminuria, hematuria, frequent micturition, urinary system infection, interstitial nephritis, glucose in urine, orchiodynia.Visible hemolytic anemia.Visible erubescence, drying.Rare heliosensitivity, erythema multiforme, Stevens Johnson syndrome, toxicity epidermal necrolysis, alopecia.Rare blurred vision.Rare perspiration increases, hyponatremia, gynecomastia.Rare arthralgia, myalgia, muscular strength weaken.Rare leukopenia, thrombocytopenia, agranulocytosis and pancytopenia.4, aluminium hydroxide: 1. contraindication: strong basicity digestive juice secretion deficiency or acatharsia person, fracture patient, the hypophosphatemia patient such as bile, pancreatic juice are arranged and the aluminium hydroxide allergy sufferers is forbidden.2. be cautious use of: the Acute Abdomens such as renal insufficiency person, prolonged constipation person, old people, appendicitis are cautious use of.3. can cause nausea, the symptom such as vomiting, constipation.Take in a large number for a long time, can cause serious constipation, even the coproma piece causes intestinal obstruction.4. the chronic renal failure patients long-term taking can cause encephalopathy, dementia and small cell anemia etc.5, cimetidine: 1. contraindication: anemia of pregnant woman, women breast-feeding their children's forbidding.2. be cautious use of: serious heart and respiratory system disease, chronic inflammatory disease are cautious use of as systemic lupus erythematosus (sle) (SLE), encephalosis, renal function injury, hepatic insufficiency, child.3. more common untoward reaction has diarrhoea, dizziness, weak, headache and erythra etc.; Can cause gynaecomastia, women's galactorrhea, hyposexuality, sexual impotence, sperm count minimizing etc. when the useful agents amount is larger, can pass through blood-cerebrospinal fluid barrier, there is certain neurotoxicity.Accidental abalienation, the untoward reaction that this product is rare has: anaphylaxis, heating, arthralgia, myalgia, granulocytopenia, thrombocytopenia, interstitial nephritis, hepatotoxicity, bradycardia, tachycardia etc.6, rabeprazole: 1. contraindication: anemia of pregnant woman, women breast-feeding their children's forbidding.2. be cautious use of: anaphylaxis or other untoward reaction persons, the patient of liver dysfunction once occurred while previously using the medicine such as lansoprazole, omeprazole, pantoprazole, the gerontal patient should be cautious use of this medicine.3. visible light-sensitive reaction, erythra, pruritus, edema, visual disorder, myalgia, rhinitis.Visible xerostomia, abdominal distention, stomachache, accidentally feel sick, vomiting, constipation, diarrhoea.Rare cardiopalmus, bradycardia, chest pain.Visible dizzy, limbs fatigue, insensitive, accidental headache, rare insomnia, sleepy, grip are low, inarticulateness, lurch.Accidental blood urea nitrogen raises, albuminuria.4. use this medicine can cause erythrocyte, lymphopenia, leukopenia or increase the symptoms such as eosinophilic granulocyte, neutrophilic leukocytosis.5. use this medicine can cause the phenomenons such as propylhomoserin aminotransferase, AST, alkali phosphatase total bilirubin, T-CHOL rising.6. use this medicine likely to cover the gastric cancer symptom, therefore should on the basis of getting rid of malignant tumor, use this medicine.7, domperidone: 1. contraindication: Patients With Pheochromocytoma, patient with breast cancer, mechanical intestinal obstruction patient, gastrointestinal hemorrhage patient and anemia of pregnant woman's forbidding.2. be cautious use of: 1 years old Infants Below, allergic constitution person, cardiac or hypokalemia patient and the tumor patient of accepting chemotherapy are cautious use of.3. accidental headache, dizziness, drowsiness, asthenia, nervousness etc., extrapyramidal symptoms, epilepsy etc., visible abdominal cramps pain, xerostomia, diarrhoea; Use larger dose can cause the non-lactation period lactogenic, arrhythmia can occur, accidental evanescent eruption or pruritus.8, famotidine: 1. contraindication: those who are allergic to this drug, severe renal functional defect person, anemia of pregnant woman, women breast-feeding their children's forbidding.2. be cautious use of: have drug allergy history, liver, renal insufficiency person, infant to be cautious use of.3. can cause constipation, nausea,vomiting,diarrhea, abdominal discomfort, xerostomia, inappetence, parotitis and dysgeusia; Period in a medicine, the detection index of liver function can raise; Most headache, rare have dizziness, confusion, anxiety, paraesthesia, depression, insomnia, general lassitude is unable and drowsiness etc., and rare neutrophilic granulocyte reduces and thrombocytopenia, the eosinophilia, and rare libido reduces; Rare erythra, urticaria, alopecia, acne, pruritus, xerosis cutis and flushing; Rare cardiopalmus, bradycardia, atrioventricular block, increased blood pressure, menoxenia, answer monitor ECG to change during medication; Rare toxic epidermal necrolysis; Rare hallucination, epilepsy grand mal, medication should be noted the patient clinical performance; Can cause tinnitus; Musculoskeletal pain, comprise muscle cramp and arthralgia; Can cause pars orbitalis edema, facial edema, conjunctival congestion, vasodilation, drug fever, urticaria and erythra etc.9, metoclopramide: can cause that drowsiness, weak, extrapyramidal system syndrome and spirit are uneasy etc.Not yet clear and definite on the fetus impact, thus should not be for vomiting during pregnancy, and the anemia of pregnant woman is cautious use of.10, carbenoxolone: there is the aldosterone effect, therefore can cause hypertension, water-sodium retention, low potassium alkali is poisoning and myopathy etc.Old people, hyperpietic are cautious use of, and hepatic and kidney function obstacle, recessive heart failure person avoid use.

Summary of the invention

For overcoming above-mentioned shortcoming, the objective of the invention is to invent a kind of Chinese medicinal preparation method for the treatment of the heat-toxin type reflux esophagitis.

The heat-toxin type reflux esophagitis refers to cause the inflammation of distal esophagus mucosa due to stomach or the anti-esophagus that flows into of intestinal contents." Medical Treasures of the Golden Chamber " is called regurgitation.In " vomiting sound of vomiting diarrhea disease ", point out: " eating in the morning but vomiting out in the evening, vomiting out in the morning what eaten at last night, indigested food stagnated in the stomach, name is said regurgitation ".Its card be eat after, stop in stomach and do not change, towards trencherman's vomiting at night, declining trencherman is towards telling, " Jing Yue's complete work is dysphagic " said: " regurgitation person, eat still can enter, and enters and instead go out, therefore say regurgitation.

etiology and pathogenesis:it is the higher-pressure region of long 2～5 centimetres that lower esophageal is crossed diaphragm segment, and this place's pressure is high at the bottom of than stomach, though it plays the barrier action of sphincter sample anatomically without sphincteral structure between the esophagus stomach function regulating, therefore be called lower esophageal sphincter.When intragastric pressure increases, the pressure of LES is also along with increasing, to avoid stomach, the anti-esophagus that flows into of intestinal contents.LES is subject to the adjusting of vagus nerve and hormone.Drink, smoking, all can make the miopragia of LES, cause the anti-esophagus that flows to of gastrointestinal contents.So the hydrochloric acid in gastric juice and pepsin, the cholate in gallbladder, pancreatic juice and LYSOLECITHIN SUNLECITHIN A etc. can be damaged mucous membrane of esophagus, cause esophagitis.Mucous membrane of esophagus be subject to counter flow thing infringement after, the squamous cell on mucosa top layer comes off, and the basal layer cell hypertrophy, thickens, and produces more new cell with the compensatory cells of superficial layer come off, therefore jejune epithelial increasing proportion in mucosa.In addition, blood vessel mastoid process hypertrophy, blood tube bundle and the teleneuron of following extend, and even can reach the surface of epithelium.Due to these changes, the visible mucous membrane of esophagus of endoscope is hyperemia, edema, crisp and easy hemorrhage, rotten to the corn, shallow table ulcer, or, with exudate, mucosa is graininess sometimes, or white macula is arranged.Have damp and hot, " heat very poison ", pyretic toxicity occupies upper, and sends out primary disease.

clinical manifestation:xerostomia, conjunctival congestion, constipation.Under normal circumstances, Esophagus has the keratinization top layer, the epithelial cell attenuation on keratinization top layer or come off fully, heart burn.Burn feeling can involve to neck, interscapular region, ear, two upper arm even, and Chang Yu occurs after the meal soon, or, strenuous exercise anteflexion at trunk, lies on the back or occur during lateral position.Instead flow than severe one, when trunk is anteflexion or lie in bed, often have the stomach of acidity or bitterness or intestinal contents to overflow into oral cavity.Along with the progress of the course of disease, the burn feeling attack times reduces, and engenders acataposis.The intermittent obstruction sense is arranged when swallowing food, and severe one can be with swallowing pain.Red tongue, yellow fur, rapid pulse.

its technical scheme:get Radix Stellariae 6 weight portions, Herba Oxalidis Corniculatae 6 weight portions, Fructus rhamni (Rhamnus davurica Pall.) 6 weight portions, Herba veronicastri villosuli 6 weight portions, Herba Meliloti Suaveolentis 3 weight portions, Herba cassiae occidentalis 6 weight portions, Cortex Alstoniae scholaris 6 weight portions, Herba Lophatheri 12 weight portions, Semen phaseoli radiati 18 weight portions, Herba Taraxaci 18 weight portions, Herba hylotelephii erythrosticti 3 weight portions, Radix Thalictri brevipedis 6 weight portions, Folium et cacumen Breyniae Fruticosae 9 weight portions, Herba desmodii microphylli 6 weight portions, Calyx seu fructus physalis 3 weight portions, Rhizoma jeffersoniae dubiae 6 weight portions, Radix Rhapontici 9 weight portions, Fructus Canarii albi 9 weight portions, Lemmaphyllum microphullum Presl 6 weight portions, Herba Rostellulariae 9 weight portions, Resina garciniae 1 weight portion, Herba Potentillae Discoloris 6 weight portions, Radix Aristolochiae 9 weight portions, Radix Curcumae 9 weight portions, Fructus Citri grandis 6 weight portions, Fructus Aurantii Immaturus 9 weight portions, Fructus Citri junoris 6 weight portions, Spica Prunellae 9 weight portions, Semen Celosiae 6 weight portions, Flos Buddlejae 3 weight portions, Flos Eriocauli 3 weight portions, Herba Equiseti Hiemalis 6 weight portions, Flos Chrysanthemi 12 weight portions, Herba Menthae 12 weight portions, Periostracum Cicadae 9 weight portions, Radix Scutellariae 6 weight portions and Radix Glycyrrhizae 9 weight portions, put into 1800 ml waters by above 37 flavor Chinese medicines, soaks 35 minutes, and then slow fire is fried 30 minutes, boil medicine altogether 390 milliliters of liquid of filter and remove residue, and fried medicinal liquid is the Chinese medicine for the treatment of heat-toxin type reflux esophagitis.

the advantage of this invention:we's 37 flavor Chinese medicines, all can buy in pharmacy, makes simply, and the herb liquid toxic and side effects of making is little, short treating period, and cure rate is high.Monarch, just right.In the time of application Chinese medicine, untoward reaction, anaphylaxis and the toxic reaction of having avoided the Western medicine antibacterials to cause.Radix Stellariae, Herba Oxalidis Corniculatae, Fructus rhamni (Rhamnus davurica Pall.), Herba veronicastri villosuli, Herba Meliloti Suaveolentis, Herba cassiae occidentalis, Cortex Alstoniae scholaris, Herba Lophatheri, Semen phaseoli radiati, Herba Taraxaci, Herba hylotelephii erythrosticti, Radix Thalictri brevipedis, Folium et cacumen Breyniae Fruticosae, Herba desmodii microphylli, Calyx seu fructus physalis, Rhizoma jeffersoniae dubiae, Radix Rhapontici, Fructus Canarii albi, Lemmaphyllum microphullum Presl, Herba Rostellulariae, Resina garciniae, Herba Potentillae Discoloris, above 22 flavor medical instruments have the effect of heat clearing and damp drying, eliminating fire and detoxication, cooling blood for hemostasis, reducing swelling and alleviating pain, clearing away heat-damp and promoting diuresis, eliminating stasis to stop pain.In the process for the treatment of heat-toxin type reflux esophagitis, play the primary treatment effect, therefore be monarch drug.Radix Aristolochiae, Radix Curcumae, Fructus Citri grandis, Fructus Aurantii Immaturus, Fructus Citri junoris, Spica Prunellae, Semen Celosiae, Flos Buddlejae, Flos Eriocauli, Herba Equiseti Hiemalis, Flos Chrysanthemi, Herba Menthae, Periostracum Cicadae, above 13 flavor medical instruments have promoting the circulation of QI to relieve pain, removing toxic substances and promoting subsidence of swelling, heat clearing and damp drying, removing toxic substances to ward off the effect of dirty, mass dissipating and swelling eliminating, heat clearing away nourishing the liver.In the process for the treatment of heat-toxin type reflux esophagitis, can assist principal agent performance therapeutical effect, therefore be ministerial drug.Radix Scutellariae: hardship, cold.Enter the heart, lung, gallbladder, large intestine four warps.Heat clearing and damp drying, clearing away the heat in SHAO YANG, resolving heat and reducing pathogenic fire, the painful abdominal mass that disappears that expels the heat-evil, clearing away heat to stop bleeding, clearing heat and preventing abortion.The through focus of all medicines of this flavor medicine energy rate, therefore be adjuvant drug.Radix Glycyrrhizae: sweet, flat.Enter 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.Can entangle the bias of all medicines, can alleviate again the toxicity of all medicines, therefore for making medicine.Radix Stellariae, Herba Oxalidis Corniculatae, Fructus rhamni (Rhamnus davurica Pall.), Herba veronicastri villosuli, Herba Meliloti Suaveolentis, Herba cassiae occidentalis, Cortex Alstoniae scholaris, Herba Lophatheri, Semen phaseoli radiati, Herba Taraxaci, Herba hylotelephii erythrosticti, Radix Thalictri brevipedis, Folium et cacumen Breyniae Fruticosae, Herba desmodii microphylli, Calyx seu fructus physalis, Rhizoma jeffersoniae dubiae, Radix Rhapontici, Fructus Canarii albi, Lemmaphyllum microphullum Presl, Herba Rostellulariae, Resina garciniae, Herba Potentillae Discoloris, Radix Aristolochiae, Radix Curcumae, Fructus Citri grandis, Fructus Aurantii Immaturus, Fructus Citri junoris, Spica Prunellae, Semen Celosiae, Flos Buddlejae, Flos Eriocauli, Herba Equiseti Hiemalis, Flos Chrysanthemi, Herba Menthae, Periostracum Cicadae, above 37 flavor medicines, there is heat clearing and damp drying, eliminating fire and detoxication, cooling blood for hemostasis, reducing swelling and alleviating pain, clearing away heat-damp and promoting diuresis, eliminating stasis to stop pain, promoting the circulation of QI to relieve pain, removing toxic substances and promoting subsidence of swelling, mass dissipating and swelling eliminating, the effect of heat clearing away nourishing the liver.Monarch, compatibility is proper, is the optimum formula for the treatment of heat-toxin type reflux esophagitis.Radix Stellariae: sweet, bitter, be slightly cold.Enter liver, stomach warp.Reducing the asthenic fever, asthenia, clearing heat in indigestion.Herba Oxalidis Corniculatae: sour, micro-puckery, cold.Enter lung, stomach warp.Clearing away heat-damp and promoting diuresis, subduing swelling and detoxicating, cooling blood for hemostasis.Fructus rhamni (Rhamnus davurica Pall.): sweet, bitter, cold.Enter liver,kidney,spleen three warps.Clearing away heat-damp and promoting diuresis, invigorating the spleen for dissipating phlegm.Herba veronicastri villosuli: hot, bitter, cold.Enter liver, lung, kidney three warps.Heat-clearing and toxic substances removing, the capable water of dampness removing, eliminating stasis to stop pain.Herba Meliloti Suaveolentis: hot, bitter, cool, nontoxic.Enter liver, spleen, stomach warp.Heat-clearing and toxic substances removing, heat clearing and damp drying, inducing diuresis for treating stranguria syndrome.Herba cassiae occidentalis: hardship, cold.Enter lung, liver, stomach warp.Relieving cough and asthma, liver heat removing and eyesight improving, stomach function regulating help digestion, subduing swelling and detoxicating, inducing diuresis for treating stranguria syndrome, relieving constipation by purgation.Cortex Alstoniae scholaris: bitter, light, cold.Enter lung, Liver Channel.Heat-clearing and toxic substances removing, hemostasia and detumescence.Herba Lophatheri: sweet, light, cold.Enter the heart, stomach, kidney, small intestine meridian.Relieving restlessness, heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome, Qinghua heat-phlegm clear away heart-fire.Semen phaseoli radiati: sweet, cold.Enter the heart, spleen, stomach, lung meridian.Heat-clearing and toxic substances removing, relieve heat and thirst, inducing diuresis to remove edema, QI invigorating skin moistening, the thick intestinal of clearing stomach.Herba Taraxaci: bitter, sweet, cold.Enter liver, stomach warp.Heat-clearing and toxic substances removing, clearing away heat-damp and promoting diuresis, tonneau urine.Herba hylotelephii erythrosticti: bitter, sour, cold.Enter the heart, liver, kidney, large intestine channel.Heat-clearing and toxic substances removing, cooling blood for hemostasis.Radix Thalictri brevipedis: hardship, cold, nontoxic.Enter lung, the heart, spleen, large intestine channel.Clearing away damp-heat, heat-clearing and toxic substances removing, lowering the adverse-rising QI to subdue asthma.Folium et cacumen Breyniae Fruticosae: hardship, cold.Enter large intestine, Liver Channel.Heat-clearing and toxic substances removing, removing stasis to stop bleeding.Herba desmodii microphylli: sweet, bitter, cold.Enter spleen, stomach, the heart, kidney channel.Heat-clearing and toxic substances removing, invigorating spleen to remove dampness, clearing away heat-damp and promoting diuresis.Calyx seu fructus physalis: sour, bitter, cold.Enter lung, spleen channel.Clearing heat, eliminating phlegm, relieving cough, heat-clearing and toxic substances removing, treatment edema.Rhizoma jeffersoniae dubiae: hardship, cold.Enter the heart, liver, stomach, large intestine channel.Heat-clearing and toxic substances removing, cooling blood for hemostasis, the treatment diarrhea due to damp-heat.Radix Rhapontici: bitter, salty, cold.Enter stomach, large intestine two warps.Heat-clearing and toxic substances removing, detumescence and apocenosis, treatment galactozemia, logical muscle arteries and veins, cooling blood for hemostasis.Fructus Canarii albi: sweet, puckery, sour, flat.Enter lung, stomach two warps.Clearing away lung-heat to relieve cough, heat-clearing and toxic substances removing sore-throat relieving, promoting the production of body fluid to quench thirst, removing toxic substances dysentery relieving, checking hyperfunction of the liver for relieving convulsion, solution Trionyx sinensis Wiegmann poison.Lemmaphyllum microphullum Presl: hot, sweet, micro-hardship, cool.Enter lung, spleen, stomach, kidney four warps.Heat-clearing and toxic substances removing, cooling blood for hemostasis, nourishing the lung to arrest cough, expelling wind and dampness, clearing away heat-damp and promoting diuresis, treatment lithangiuria, acute toothache, fulminant dysentery.Herba Rostellulariae: salty, micro-suffering, micro-hardship, cold.Enter liver, gallbladder, spleen three warps.Heat-clearing and toxic substances removing, dampness removing stagnant, the promoting blood circulation and stopping pain that disappears.Resina garciniae: sour, puckery, cold.Very toxic.Enter spleen, stomach, large intestine three warps.Removing toxic substances and promoting subsidence of swelling, astringing to arrest bleeding, parasite killing are treated skin ulcer.Herba Potentillae Discoloris: sweet, micro-hardship, flat (cooler).Enter liver, stomach, large intestine three warps.Heat-clearing and toxic substances removing, cooling blood for hemostasis.Radix Aristolochiae: hot, bitter, cold.Enter liver, stomach two warps.Promoting the circulation of QI to relieve pain, removing toxic substances and promoting subsidence of swelling, heat clearing and damp drying, removing toxic substances are warded off dirty.Radix Curcumae: hot, bitter, cold.Enter the heart, lung, liver three warps.Promoting QI circulation for relieving depression, promoting blood circulation and breaking stagnation, removing heat from blood clear away heart-fire, cooling blood for hemostasis, promoting the function of the gallbladder to alleviate jaundice.Fructus Citri grandis: hot, sweet, sour, cold.Enter liver, spleen, stomach three warps.Regulating the flow of QI to ease the stomach, preventing phlegm from forming and stopping coughing, alcoholic intoxication.Fructus Aurantii Immaturus: bitter, hot, micro-acid are slightly cold.Enter spleen, stomach, liver, the heart four warps.The dispelling the stagnated QI removing food stagnancy, reduce phlegm disappear painful abdominal mass, regulating the flow of vital energy reaches that strongly fragrant, the detumescence of relieving oedema or abdominal distension through diuresis or purgation, treatment rubella hardship are itched, the proctoptosis prolapse of the uterus.Fructus Citri junoris: acid, cool, nontoxic.Enter lung, liver, stomach three warps.Regulating the stomach and sending down the abnormal ascending QI, the chest stuffiness relieving relieving accumulation of pathogens, the wart that disappears, the poison that kills the fish Eriocheir sinensis.Spica Prunellae: hardship; Cold; Hot; Enter liver, gallbladder, spleen channel.Fire, heat clearing away eliminating stagnation are let out in liver heat removing.Semen Celosiae: hardship, cool.Enter Liver Channel.Liver heat removing, town liver, liver heat removing and eyesight improving, heat clearing and damp drying, the heat of dispeling the wind.Flos Buddlejae: sweet, cold.Enter Liver Channel.The liver heat removing nebula removing, nourishing the liver to improve visual acuity, dispelling wind heat clearing and blood cooling.Flos Eriocauli: hot, sweet, cool.Enter liver, stomach warp.Wind and heat eliminating, improving acuity of vision and removing nebula, the treatment heat in blood is hemorrhage.Herba Equiseti Hiemalis: sweet, bitter, flat.Enter lung, liver, gallbladder meridian.Wind and heat dispersing, improving acuity of vision and removing nebula, cooling blood for hemostasis.Flos Chrysanthemi: be slightly cold; Sweet, bitter; Return lung, Liver Channel.Dispelling wind and heat pathogens, the suppressing the hyperactive liver improving eyesight.Herba Menthae: suffering; Cool; Nontoxic, return lung, Liver Channel.Clearing away heat and expelling pathogen in the exterior, the clear sharp head, treatment irritability stasis, rash.Periostracum Cicadae: sweet, cold, cool.Enter lung, Liver Channel.Dispelling wind and heat pathogens, improving acuity of vision and removing nebula, expelling wind and relieving convulsion.Radix Scutellariae: hardship, cold.Enter the heart, lung, gallbladder, large intestine four warps.Heat clearing and damp drying, clearing away the heat in SHAO YANG, resolving heat and reducing pathogenic fire, the painful abdominal mass that disappears that expels the heat-evil, clearing away heat to stop bleeding, clearing heat and preventing abortion.Radix Glycyrrhizae: sweet, flat.Enter 12 warps.Spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.

The specific embodiment

Get Radix Stellariae 6g, Herba Oxalidis Corniculatae 6g, Fructus rhamni (Rhamnus davurica Pall.) 6g, Herba veronicastri villosuli 6g, Herba Meliloti Suaveolentis 3g, Herba cassiae occidentalis 6g, Cortex Alstoniae scholaris 6g, Herba Lophatheri 12g, Semen phaseoli radiati 18g, Herba Taraxaci 18g, Herba hylotelephii erythrosticti 3g, Radix Thalictri brevipedis 6g, Folium et cacumen Breyniae Fruticosae 9g, Herba desmodii microphylli 6g, Calyx seu fructus physalis 3g, Rhizoma jeffersoniae dubiae 6g, Radix Rhapontici 9g, Fructus Canarii albi 9g, Lemmaphyllum microphullum Presl 6g, Herba Rostellulariae 9g, Resina garciniae 1g, Herba Potentillae Discoloris 6g, Radix Aristolochiae 9g, Radix Curcumae 9g, Fructus Citri grandis 6g, Fructus Aurantii Immaturus 9g, Fructus Citri junoris 6g, Spica Prunellae 9g, Semen Celosiae 6g, Flos Buddlejae 3g, Flos Eriocauli 3g, Herba Equiseti Hiemalis 6g, Flos Chrysanthemi 12g, Herba Menthae 12g, Periostracum Cicadae 9g, Radix Scutellariae 6g and Radix Glycyrrhizae 9g, above 37 flavor medicines are put into 1800 ml waters together, soak 35 minutes, then slow fire is fried 30 minutes, filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of heat-toxin type reflux esophagitis.Boil medicine altogether 390 milliliters of liquid, when the client need treatment of heat-toxin type reflux esophagitis, making fluid temperature is 36 ℃, each 130 milliliters, oral, every day three times, within 2nd, be a course for the treatment of, if symptom is still deposited, then took for second course for the treatment of, so that recovery from illness.

In 391 routine heat-toxin type patients with reflux esophagitis, male's 238 examples, account for 60.87%; Women's 153 examples, account for 39.13%.The male is more than the women.

The range of age of table one, 391 routine heat-toxin type patients with reflux esophagitis

Age (year)	18～20	21～35	36～56	57～60
					Number of cases	13	261	112	5
Percentage ratio	3.32%	66.75%	28.65%	1.28%

Table two, 391 routine heat-toxin type patients with reflux esophagitis curative effect tables

Curative effect	Cure	Take a turn for the better	Invalid
				Number of cases	390	1	Nothing
Percentage ratio	99.74%	0.26%	Nothing

Table three, the 391 routine heat-toxin type patients with reflux esophagitis tables course for the treatment of

The treatment natural law	3～5	6～9	10～15	16～26
					Number of cases	13	309	62	7
Percentage ratio	3.32%	79.03%	15.86%	1.79%

Information slip before and after table four, 391 routine heat-toxin type patients with reflux esophagitis treatments

Claims (1)

1. a Chinese medicinal preparation method for the treatment of the heat-toxin type reflux esophagitis, it is characterized in that: get Radix Stellariae 6 grams, Herba Oxalidis Corniculatae 6 grams, Fructus rhamni (Rhamnus davurica Pall.) 6 grams, Herba veronicastri villosuli 6 grams, Herba Meliloti Suaveolentis 3 grams, Herba cassiae occidentalis 6 grams, Cortex Alstoniae scholaris 6 grams, Herba Lophatheri 12 grams, Semen phaseoli radiati 18 grams, Herba Taraxaci 18 grams, Herba hylotelephii erythrosticti 3 grams, Radix Thalictri brevipedis 6 grams, Folium et cacumen Breyniae Fruticosae 9 grams, Herba desmodii microphylli 6 grams, Calyx seu fructus physalis 3 grams, Rhizoma jeffersoniae dubiae 6 grams, Radix Rhapontici 9 grams, Fructus Canarii albi 9 grams, Lemmaphyllum microphullum Presl 6 grams, Herba Rostellulariae 9 grams, Resina garciniae 1 gram, Herba Potentillae Discoloris 6 grams, Radix Aristolochiae 9 grams, Radix Curcumae 9 grams, Fructus Citri grandis 6 grams, Fructus Aurantii Immaturus 9 grams, Fructus Citri junoris 6 grams, Spica Prunellae 9 grams, Semen Celosiae 6 grams, Flos Buddlejae 3 grams, Flos Eriocauli 3 grams, Herba Equiseti Hiemalis 6 grams, Flos Chrysanthemi 12 grams, Herba Menthae 12 grams, Periostracum Cicadae 9 grams, Radix Scutellariae 6 grams and Radix Glycyrrhizae 9 grams, above 37 flavor Chinese medicines are put into to 1800 ml waters, soak 35 minutes, then slow fire is fried 30 minutes, boil medicine altogether 390 milliliters of liquid of filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of heat-toxin type reflux esophagitis.