A kind of Chinese medicinal preparation method of treating hyperactive liver-qi attacking the stomach gastritis
Technical field
The present invention relates to the Chinese medicinal preparation method technical field, is a kind of Chinese medicinal preparation method of treating hyperactive liver-qi attacking the stomach gastritis more specifically.
Background technology
Present treatment hyperactive liver-qi attacking the stomach gastritis, the general employing: 1, ranitidine: 1. contraindication: to this medicine and other H
2Receptor antagonist allergy sufferers, anemia of pregnant woman, women breast-feeding their children, the forbidding of child below 8 years old.2. careful usefulness: liver, renal insufficiency person, acute hematoporphyria person, the careful usefulness of old people.3. can occur headache, dizzy, weak, obnubilation, mental act unusually, insomnia etc.; Mental symptoms such as disorientation, drowsiness, anxiety appear in liver, renal insufficiency person and gerontal patient after accidental the taking medicine; A small amount of generation blurred vision is arranged; Constipation, diarrhoea occur, feel sick, vomit, suffer from abdominal pain; Erythra can occur, only a few generation erythema multiforme is arranged; Rare arthralgia, myalgia; Rare anaphylactic reaction shows as rubella, vasodilation, heating, bronchospasm, hypotension, anaphylactic shock, chest pain etc.; Life-time service can cause vitamin B
12Lack, male breast is womanlike rare; Cause that renal dysfunction etc., quiet notes rear section patient fever sensation of the face sense, dizziness can occur, feel sick, perspiration and gastric irritation.4. this medicine has certain toxicity to liver, so in the administration process, should monitor the patients with hepatic changes of function.When 5. vein gave this medicine, bradycardia can appear.So should be slow during quiet notes, and should make regular check on electrocardiogram in the medication process.6. this medicine has certain inhibitory action to bone marrow, and moderate leukocyte of reversibility or granulocytopenia can take place small number of patients, and the thrombocytopenia of appearance and autoimmune hemolytic anemia are also arranged.2, bismuth potassium citrate: 1. contraindication: to this medicine allergy sufferers, severe renal functional defect, anemia of pregnant woman patient's forbidding.2. careful usefulness: hepatic disfunction person, child, the careful usefulness of women breast-feeding their children.3. small number of patients can have slight headache, dizziness, insomnia etc.; Erythra can appear in individual patient; Possibly have ammonia flavor in mouthful, and tongue, feces can be dyed black, be prone to obscure mutually with tarry stool; Can occur when individual patient is taken feeling sick, symptom of digestive tract such as diarrhoea, constipation, loss of appetite, diarrhoea.4. long-term large dose oral administration possibly cause Toxicity of Kidney, causes the reversibility renal failure, and with 10 days in outbreak, should make regular check on renal function.5. the untoward reaction of the skeleton relevant osteoarthritis of bismuth encephalopathy (HIE) more commonly is a premonitory symptom with one-sided or both shoulders pain often.3, aluminium hydroxide: 1. contraindication: strong basicity digestive juice secretion deficiency or acatharsia person, fracture patient, hypophosphatemia patient such as bile, pancreatic juice are arranged and the aluminium hydroxide allergy sufferers is forbidden.2. careful usefulness: the careful usefulness of acute abdomen patient such as renal insufficiency person, prolonged constipation person, old people, appendicitis.3. can cause nausea, symptom such as vomiting, constipation.Take in a large number for a long time, can cause serious constipation, even the coproma piece causes intestinal obstruction.4. patients with renal failure is taken for a long time and can be caused encephalopathy, dementia and small cell anemia etc.4, cimetidine: 1. contraindication: anemia of pregnant woman, women breast-feeding their children's forbidding.2. careful usefulness: serious heart and respiratory system disease, chronic inflammatory disease such as systemic lupus erythematosus (sle) (SLE), encephalosis, renal function injury, hepatic insufficiency, the careful usefulness of child.3. more common untoward reaction has diarrhoea, dizziness, weak, headache and erythra etc.; The useful agents amount can cause gynaecomastia, women's galactorrhea, hyposexuality, sexual impotence, sperm count minimizing etc. when big, can pass through blood-cerebrospinal fluid barrier, has certain neurotoxicity.Accidental abalienation, the rare untoward reaction of these article has: anaphylaxis, heating, arthralgia, myalgia, granulocytopenia, thrombocytopenia, interstitial nephritis, hepatotoxicity, bradycardia, tachycardia etc.5, famotidine: 1. contraindication: to this medicine allergy sufferers, severe renal functional defect person, anemia of pregnant woman, women breast-feeding their children's forbidding.2. careful usefulness: drug allergy history, liver, renal insufficiency person, infant Ying Shenyong are arranged.3. can cause constipation, nausea,vomiting,diarrhea, abdominal discomfort, xerostomia, inappetence, parotitis and dysgeusia; Period in a medicine, the detection index of liver function can raise; Most headache rare has dizziness, confusion, anxiety, paraesthesia, depression, insomnia, general lassitude is unable and drowsiness etc., and rare neutrophilic granulocyte reduces and thrombocytopenia, the eosinophilia, and rare libido reduces; Rare erythra, urticaria, alopecia, acne, pruritus, xerosis cutis and flushing; Rare cardiopalmus, bradycardia, atrioventricular block, increased blood pressure, menoxenia should be monitored electrocardiogram and changed during the medication; Rare toxic epidermal necrolysis; Rare hallucination, epilepsy grand mal, medication should be noted patient's clinical manifestation; Can cause tinnitus; Musculoskeletal pain comprises muscle cramp and arthralgia; Can cause pars orbitalis edema, facial edema, conjunctival congestion, vasodilation, drug fever, urticaria and erythra etc.6, omeprazole: 1. contraindication: to this medicine allergy sufferers, severe renal functional defect person, anemia of pregnant woman, infant patient's forbidding.2. careful usefulness: liver, renal insufficiency person, women breast-feeding their children, gerontal patient Ying Shenyong.3. common adverse reactions be diarrhoea, headache, feel sick, stomachache, flatulence and constipation, accidental serum aminotransferase increases, erythra, dizzy, drowsiness, insomnia etc.; It is thus clear that chest pain, cardiopalmus, tachycardia or slow excessively, hypertension, periphery edema.It is thus clear that microscopic pyuria, albuminuria, hematuria, frequent micturition, urinary system infection, interstitial nephritis, glucose in urine, orchiodynia.It is thus clear that hemolytic anemia.It is thus clear that erubescence, drying.Rare heliosensitivity, erythema multiforme, Stevens Johnson syndrome, toxicity epidermal necrolysis, alopecia.Rare blurred vision.Rare perspiration increases, hyponatremia, gynecomastia.Rare arthralgia, myalgia, muscular strength weaken.Rare leukopenia, thrombocytopenia, agranulocytosis and pancytopenia.7, rabeprazole: 1. contraindication: anemia of pregnant woman, women breast-feeding their children's forbidding.2. careful usefulness: anaphylaxis or other untoward reaction persons, the patient of liver dysfunction were taken place once when previously using medicine such as lansoprazole, omeprazole, pantoprazole, gerontal patient Ying Shen uses this medicine.3. visible light-sensitive property reaction, erythra, pruritus, edema, visual disorder, myalgia, rhinitis.It is thus clear that xerostomia, abdominal distention, stomachache are accidentally felt sick, vomiting, constipation, diarrhoea.Rare cardiopalmus, bradycardia, chest pain.It is thus clear that dizzy, limbs fatigue, insensitive, accidental headache, rare insomnia, sleepy, grip are low, inarticulateness, lurch.Accidental blood urea nitrogen raises, albuminuria.4. use this medicine can cause erythrocyte, lymphopenia, leukopenia or increase symptoms such as EC, neutrophilic leukocytosis.5. use this medicine can cause phenomenons such as propylhomoserin aminotransferase, Aspartic Acid aminotransferase, alkali phosphatase STB, T-CHOL rising.6. use this medicine might cover the gastric cancer symptom, so should on the basis of getting rid of malignant tumor, use this medicine.8, atropine: 1. contraindication: to this medicine or the not anti-receptor of other Semen daturae Alkaloids, glaucoma and prostate increase person, hyperpyrexia patient, acute penta sodium pentachlorophenate poisoner, myasthenia gravis patient.2. careful usefulness: patient, patients of ulcerative colitis, cerebral lesion person, diarrhea patient, gastric ulcer patient, the fever patient Ying Shenyong of illness such as the hypomotility of heart disease patient, reflux esophagitis, stomach pyloric obstruction, esophagus and stomach, relaxation of lower esophageal sphincter.3. common constipation, the minimizing of perspiring, mouth and nose dry laryngopharynx, blurred vision, erubescence, dysuria, low, the stomach-esophageal reflux of digestive tract power.Rare intraocular pressure rising, allergic rash or herpes.Can occur the dry heating of skin mucosa, flush, tachycardia, blurred vision, of short duration eye burn feeling and twinge, photophobia, eyelid swelled etc. behind the ophthalmic administration, anaphylaxiss such as pruritus, redness, conjunctival congestion appear in the small number of patients eyelid.4. xerostomia, heart rate acceleration, pupil slightly enlarge; Blurred vision; Slurred speech, dysphoria, xerosis cutis heating, urine difficulty, enterokinesia reduce; Rapid pulse and a little less than, the serious accelerated breathing of central excitation phenomenon is deepened, and delirium, hallucination, convulsions etc. occur; Can change inhibition over to by central excitation during serious the poisoning, produce stupor and respiratory paralysis etc.The minimum lethal dose (MLD) adult is about 80 ~ 130mg, and the child is 10mg.9, domperidone: 1. contraindication: pheochromocytoma patient, patient with breast cancer, mechanical intestinal obstruction patient, gastrointestinal hemorrhage patient and anemia of pregnant woman's forbidding.2. careful usefulness: infant below 1 years old, allergic constitution person, cardiac or hypokalemia patient and accept the careful usefulness of tumor patient of chemotherapy.3. accidental headache, dizziness, drowsiness, asthenia, nervousness etc., EPS, epilepsy etc., visible abdominal cramps property pain, xerostomia, diarrhoea; Use can cause the non-lactation period lactogenic than heavy dose, arrhythmia can occur, accidental evanescent eruption or pruritus.
Summary of the invention
For overcoming above-mentioned shortcoming, the objective of the invention is to invent a kind of Chinese medicinal preparation method of treating hyperactive liver-qi attacking the stomach gastritis.Gastric abscess is claimed in stomachache again, is that with upper abdomen gastral cavilty portion nearly pit of the stomach place pain often to take place be main symptom.Say like " element is asked the hexa-atomic big opinion piece of writing of just recording ": " strongly fragrant the sending out of wood, the sick epigastralgia right below the heart of the people." " Ling Shu Miraculous Pivot or Divine Axis pathogen cacosplanchnia shape " piece of writing point out: " the stomach patient, the abdomen moon is very bloated, epigastralgia right below the heart." " the pained side of medical secrets of official " say: " the foot sun is bright be the warp of stomach, and the deficiency of vital energy is contrary takes advantage of the heart and pain, and its shape abdominal distention belongs to the heart and bitterly very.The epigastralgia of meaning also." the pained gastric abscess that all is meant here.So-called epigastric oppression in treatise on Febrile Diseases, feeling soft in the abdomen while pressing, or epigastric oppression, the pain of pressing etc., the real stomach that all refers to.Saying of ancient prescription nine types of precordial pain also refers to stomachache more." medical science main story gastric abscess " also said: " the ancient prescription nine types of precordial pain ... detailed its reason.All at gastral cavilty, and do not lie in the heart in fact yet.”
Etiology and pathogenesis: liver being bold and firm viscera, property happiness bar reaches and main catharsis, if it is angry to be worried, the then stagnation of QI and impairing the liver, edema with the liver involved is lost in catharsis, and perverse and unreasonable manner is violated stomach, causes the mechanism of qi retardance, thereby pain takes place.Said like " the Shen Shi honor is given birth to the book stomachache ": " stomachache, evil dried gastral cavilty disease also.Only irritability multiplies each other for more so, and is sudden and violent with wood property, and just restraining also." clinical manifestation: epigastric distension and distress; Attack support and have a pain, gastralgia connects the side of body, and belch is frequent, and it is not smooth to defecate, and every because of feelings will factor pain work, how thin white tongue is, deep and stringy pulse.
Its technical scheme is: get Fructus Trichosanthis 6 weight portions, Bulbus Allii Macrostemonis 9 weight portions, Semen Citri Reticulatae 3 weight portions, Pericarpium Citri tangerinae 9 weight portions, Fructus Citri junoris 6 weight portions, Semen Aesculi 3 weight portions, Nicotiana tabacum L. 6 weight portions, Fructus Citri 9 weight portions, Rhizoma Cyperi 9 weight portions, Cortex Magnoliae Officinalis 6 weight portions, Semen Litchi 9 weight portions, Fructus Litchi 9 weight portions, Semen Raphani 12 weight portions, Fructus Caricae 3 weight portions, Rhizoma Iridis Tectori 9 weight portions, Radix Dauci Sativae 12 weight portions, Semen Fagopyri Esculenti 12 weight portions, Massa Medicata Fermentata 9 weight portion 、 Fructus cydoniae oblongae 12 weight portions, the Radix Aucklandiae 6 weight portions and Radix Glycyrrhizae 9 weight portions; Above 21 flavor Chinese medicines are put into 1500 ml waters; Soaked 30 minutes; Slow fire is fried 30 minutes then; Filter and remove residue; Boil medicine altogether 360 milliliters of liquid, fried medicinal liquid is the Chinese medicine of treatment hyperactive liver-qi attacking the stomach gastritis.
The advantage of this invention is: we's 21 flavor Chinese medicines, all can buy in pharmacy, and to make simply, the herb liquid toxic and side effects of processing is little, short treating period, cure rate is high.Monarch, just right.When using Chinese medicine, untoward reaction, anaphylaxis and the toxic reaction of having avoided Western medicine to cause.Fructus Trichosanthis, Bulbus Allii Macrostemonis, Semen Citri Reticulatae, Pericarpium Citri tangerinae, Fructus Citri junoris, Semen Aesculi, Nicotiana tabacum L., Fructus Citri, Rhizoma Cyperi, Cortex Magnoliae Officinalis, Semen Litchi, Fructus Litchi, more than 12 flavor medical instruments the effect of promoting the circulation of QI relieving stuffiness of the chest by dispersing aggregation of pathogens, clearing heat, eliminating phlegm, relieving cough, heat-clearing and toxic substances removing, the chest stuffiness relieving of regulating the flow of vital energy is arranged.In the process of treatment hyperactive liver-qi attacking the stomach gastritis, play main therapeutical effect, so be monarch drug.Semen Raphani, Fructus Caricae, Rhizoma Iridis Tectori, Radix Dauci Sativae, Semen Fagopyri Esculenti, Massa Medicata Fermentata 、 Fructus cydoniae oblongae, more than 7 flavor medical instruments invigorating the spleen and regulating the stomach is arranged, the effect of the removing food stagnancy that whets the appetite, the pain relieving that helps digestion.Can bring into play therapeutical effect by auxiliary principal agent, so be ministerial drug.The Radix Aucklandiae: hot, bitter, temperature.Go into lung, stomach, large intestine three friendship warps.Promoting the circulation of QI to relieve pain, invigorating the stomach and promoting digestion, the through focus of all medicines of energy rate is so be adjuvant drug.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.The bias of all medicines can be entangled, the toxicity of all medicines can be alleviated again, so be messenger drug.Fructus Trichosanthis, Bulbus Allii Macrostemonis, Semen Citri Reticulatae, Pericarpium Citri tangerinae, Fructus Citri junoris, Semen Aesculi, Nicotiana tabacum L., Fructus Citri, Rhizoma Cyperi, Cortex Magnoliae Officinalis, Semen Litchi, Fructus Litchi, Semen Raphani, Fructus Caricae, Rhizoma Iridis Tectori, Radix Dauci Sativae, Semen Fagopyri Esculenti, Massa Medicata Fermentata 、 Fructus cydoniae oblongae, the Radix Aucklandiae, Radix Glycyrrhizae; This 21 flavor medicine compatibility is used, and plays the promoting the circulation of QI relieving stuffiness of the chest by dispersing aggregation of pathogens jointly, the effect of the chest stuffiness relieving of regulating the flow of vital energy, invigorating the spleen and regulating the stomach, appetizing removing food stagnancy, the pain relieving that helps digestion.Monarch, compatibility is proper, is the optimum formula of treatment hyperactive liver-qi attacking the stomach gastritis.Fructus Trichosanthis: sweet, bitter, cold.Go into lung, stomach, large intestine three warps.Promoting the circulation of QI relieving stuffiness of the chest by dispersing aggregation of pathogens, clearing heat, eliminating phlegm, relieving cough, moisturize laxation relieving constipation, heat-clearing and toxic substances removing eliminating carbuncle.Bulbus Allii Macrostemonis: hot, bitter, temperature, nontoxic.Go into the heart, liver, lung, stomach four warps.Regulate the flow of vital energy the chest stuffiness relieving, warming spleen and stomach for dispelling cold, the pain relieving of passing through, heat-clearing and toxic substances removing.Semen Citri Reticulatae: hardship, flat, nontoxic.Go into liver, kidney two warps.Regulate the flow of vital energy cold expelling, the treatment acute mastitis from the beginning of.Pericarpium Citri tangerinae: hot, bitter, temperature, nontoxic.Go into spleen, lung two warps.Spleen invigorating is regulated the flow of vital energy, drying dampness to eliminate phlegm, inducing diuresis for treating stranguria syndrome.Fructus Citri junoris: acid, cold, nontoxic.Go into lung, liver, stomach three warps.Regulating the stomach and sending down the abnormal ascending QI, the chest stuffiness relieving relieving accumulation of pathogens, the wart that disappears, the poison that kills the fish Eriocheir sinensis.Semen Aesculi: sweet, hot, warm.Go into spleen, stomach, lung three warps.Depressed liver-energy dispersing and QI regulating, alleviating distention in middle-JIAO stomach function regulating.Nicotiana tabacum L.: hot, bitter, temperature, poisonous.Go into lung, spleen, stomach three warps.Promoting the circulation of QI to relieve pain, detoxifcation parasite killing.Fructus Citri: hot, bitter, sour, temperature.Go into liver, lung, spleen three warps.Depressed liver-energy dispersing and QI regulating and in reduce phlegm, sharp diaphragm preventing or arresting vomiting.Rhizoma Cyperi: hot, little hardship, little sweet, flat.Go into liver, three warmers two warps.Soothing liver-QI for relieving depression, menstruction regulating and pain relieving, warming for eliminaring cold-damp.Cortex Magnoliae Officinalis: bitter, hot, temperature.Go into spleen, lung, stomach, large intestine four warps.That dampness is loose is full, the diffusing painful abdominal mass that helps digestion, lowering the adverse-rising QI to subdue asthma, treatment cholera and stomachache.Semen Litchi: hot, sweet, temperature.Go into liver, kidney two warps.Regulating QI to relieve pain, warming spleen and stomach for dispelling cold.Fructus Litchi: hot, acid, sweet, temperature.Go into spleen, liver two warps.Regulating QI to relieve pain, dispersing swelling and dissipating binds, benefiting qi and checking blood, promoting the production of body fluid to quench thirst.Semen Raphani: hot, sweet, flat.Go into spleen, stomach warp.Promoting digestion and removing stagnation, lowering the adverse-rising QI to relieve dyspnea, expectorant antitussive.Fructus Caricae: sweet, flat.Go into spleen, stomach warp.The pain relieving that helps digestion, the row water conservancy is wet.Rhizoma Iridis Tectori: hot, bitter, cold, poisonous.Go into lung, liver, spleen channel.Promoting digestion and removing stagnation, blood circulation promoting and blood stasis dispelling, line water detumescence, heat-clearing and toxic substances removing, suppressing the hyperactive liver are only dizzy.Radix Dauci Sativae: sweet, hot, flat.Go into lung, spleen, stomach, kidney channel.Invigorating the spleen and regulating the stomach, relieving dyspepsia, warming the kidney to invigorate YANG, detoxifcation rash, nourishing the lung to arrest cough.Semen Fagopyri Esculenti: sweet, acid, cold.Go into spleen, stomach, large intestine channel.The appetizing removing food stagnancy, skin ulcer is treated in detoxifcation.Massa Medicata Fermentata: sweet, suffering, temperature.Go into spleen, stomach warp.The treatment diseases caused by exogenous pathogenic factor are got ill from overeating, dyspeptic vomiting and diarrhea, insufficiency of the spleen distension, galactopoiesis in puerperal, removing food stagnancy dysentery relieving, therapeutic method to keep the adverse QI flowing downwards expectorant.Fructus cydoniae oblongae: hot, acid, sweet, temperature.Go into spleen, stomach warp.The therapeutic method to keep the adverse QI flowing downwards helps digestion, and deodorization is relieved the effect of alcohol.The Radix Aucklandiae: hot, bitter, temperature.Go into lung, stomach, large intestine three friendship warps.Promoting the circulation of QI to relieve pain, invigorating the stomach and promoting digestion.Radix Glycyrrhizae: sweet, flat.Go into 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.
The specific embodiment
Get Fructus Trichosanthis 6g, Bulbus Allii Macrostemonis 9g, Semen Citri Reticulatae 3g, Pericarpium Citri tangerinae 9g, Fructus Citri junoris 6g, Semen Aesculi 3g, Nicotiana tabacum L. 6g, Fructus Citri 9g, Rhizoma Cyperi 9g, Cortex Magnoliae Officinalis 6g, Semen Litchi 9g, Fructus Litchi 9g, Semen Raphani 12g, Fructus Caricae 3g, Rhizoma Iridis Tectori 9g, Radix Dauci Sativae 12g, Semen Fagopyri Esculenti 12g, Massa Medicata Fermentata 9g 、 Fructus cydoniae oblongae 12g, the Radix Aucklandiae 6 g and Radix Glycyrrhizae 9g; More than 21 the flavor medicines put into 1500 ml waters together; Soaked 30 minutes; Slow fire is fried 30 minutes then, and filter and remove residue, fried medicinal liquid are the Chinese medicine of treatment hyperactive liver-qi attacking the stomach gastritis.Boil medicine altogether 360 milliliters of liquid, when the patient of hyperactive liver-qi attacking the stomach gastritis need treat, making fluid temperature was 36 ℃, each 120 milliliters, oral, every day three times, two is a course of treatment, if symptom is still deposited, obeys for second course of treatment again, so that recovery from illness.
Among the 376 routine hyperactive liver-qi attacking the stomach gastritis sufferers, male's 105 examples account for 27.9%; Women's 271 examples account for 72.1%.The male is more than the women.