CN103110840A - Preparation method of traditional Chinese medicine for treating pharyngalgia type reflux esophagitis - Google Patents
Preparation method of traditional Chinese medicine for treating pharyngalgia type reflux esophagitis Download PDFInfo
- Publication number
- CN103110840A CN103110840A CN2013100504884A CN201310050488A CN103110840A CN 103110840 A CN103110840 A CN 103110840A CN 2013100504884 A CN2013100504884 A CN 2013100504884A CN 201310050488 A CN201310050488 A CN 201310050488A CN 103110840 A CN103110840 A CN 103110840A
- Authority
- CN
- China
- Prior art keywords
- grams
- herba
- medicine
- pharyngalgia
- reflux esophagitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000003814 drug Substances 0.000 title claims abstract description 47
- 208000021302 gastroesophageal reflux disease Diseases 0.000 title claims abstract description 22
- 208000000689 peptic esophagitis Diseases 0.000 title claims abstract description 22
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 238000011282 treatment Methods 0.000 claims abstract description 18
- 239000007788 liquid Substances 0.000 claims abstract description 10
- 241001655769 Androsace Species 0.000 claims abstract description 7
- 241001116755 Selliguea Species 0.000 claims abstract description 6
- 239000004744 fabric Substances 0.000 claims abstract description 5
- 239000000796 flavoring agent Substances 0.000 claims description 8
- 235000019634 flavors Nutrition 0.000 claims description 8
- 241000959626 Calvatia Species 0.000 claims description 6
- 241001164374 Calyx Species 0.000 claims description 6
- 241000628997 Flos Species 0.000 claims description 6
- 241001505096 Rhamnus davurica Species 0.000 claims description 6
- 210000000582 semen Anatomy 0.000 claims description 6
- 229940126678 chinese medicines Drugs 0.000 claims description 3
- 239000003643 water by type Substances 0.000 claims description 3
- 241001106044 Physalis Species 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 8
- 230000000172 allergic effect Effects 0.000 abstract description 4
- 208000010668 atopic eczema Diseases 0.000 abstract description 4
- 238000011084 recovery Methods 0.000 abstract description 4
- 206010067484 Adverse reaction Diseases 0.000 abstract description 2
- 230000006838 adverse reaction Effects 0.000 abstract description 2
- 230000008901 benefit Effects 0.000 abstract description 2
- 210000000481 breast Anatomy 0.000 abstract description 2
- VMXUWOKSQNHOCA-LCYFTJDESA-N ranitidine Chemical compound [O-][N+](=O)/C=C(/NC)NCCSCC1=CC=C(CN(C)C)O1 VMXUWOKSQNHOCA-LCYFTJDESA-N 0.000 abstract description 2
- 229960000620 ranitidine Drugs 0.000 abstract description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract description 2
- 241000512005 Alstonia Species 0.000 abstract 1
- 241000596154 Belamcanda Species 0.000 abstract 1
- 244000104272 Bidens pilosa Species 0.000 abstract 1
- 235000010662 Bidens pilosa Nutrition 0.000 abstract 1
- 241000405421 Breynia Species 0.000 abstract 1
- 244000012254 Canarium album Species 0.000 abstract 1
- 235000009103 Canarium album Nutrition 0.000 abstract 1
- 244000062995 Cassia occidentalis Species 0.000 abstract 1
- 235000001948 Cassia occidentalis Nutrition 0.000 abstract 1
- 241001355283 Cayratia Species 0.000 abstract 1
- 235000014342 Ceanothus Nutrition 0.000 abstract 1
- 241001083940 Ceanothus Species 0.000 abstract 1
- 235000007516 Chrysanthemum Nutrition 0.000 abstract 1
- 244000189548 Chrysanthemum x morifolium Species 0.000 abstract 1
- 244000303040 Glycyrrhiza glabra Species 0.000 abstract 1
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 abstract 1
- 102000003710 Histamine H2 Receptors Human genes 0.000 abstract 1
- 108090000050 Histamine H2 Receptors Proteins 0.000 abstract 1
- 240000003915 Lophatherum gracile Species 0.000 abstract 1
- 241000133231 Marshallia caespitosa Species 0.000 abstract 1
- 244000050427 Melilotus officinalis subsp suaveolens Species 0.000 abstract 1
- 235000000839 Melilotus officinalis subsp suaveolens Nutrition 0.000 abstract 1
- 241000208167 Oxalis Species 0.000 abstract 1
- 235000008098 Oxalis acetosella Nutrition 0.000 abstract 1
- 241001465382 Physalis alkekengi Species 0.000 abstract 1
- 240000000103 Potentilla erecta Species 0.000 abstract 1
- 235000016551 Potentilla erecta Nutrition 0.000 abstract 1
- 244000072882 Sedum telephium Species 0.000 abstract 1
- 235000019098 Sedum telephium Nutrition 0.000 abstract 1
- 241000219784 Sophora Species 0.000 abstract 1
- 241001278775 Veronicastrum Species 0.000 abstract 1
- 240000004922 Vigna radiata Species 0.000 abstract 1
- 235000010721 Vigna radiata var radiata Nutrition 0.000 abstract 1
- 235000011469 Vigna radiata var sublobata Nutrition 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 235000013399 edible fruits Nutrition 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 abstract 1
- 230000000366 juvenile effect Effects 0.000 abstract 1
- 235000011477 liquorice Nutrition 0.000 abstract 1
- 239000002893 slag Substances 0.000 abstract 1
- 238000002791 soaking Methods 0.000 abstract 1
- 229940126680 traditional chinese medicines Drugs 0.000 abstract 1
- 210000004185 liver Anatomy 0.000 description 26
- 231100000614 poison Toxicity 0.000 description 26
- 239000003440 toxic substance Substances 0.000 description 25
- 210000004072 lung Anatomy 0.000 description 21
- 210000002784 stomach Anatomy 0.000 description 15
- 229940079593 drug Drugs 0.000 description 13
- 230000008961 swelling Effects 0.000 description 13
- 210000004369 blood Anatomy 0.000 description 12
- 239000008280 blood Substances 0.000 description 12
- 208000002193 Pain Diseases 0.000 description 11
- 235000009508 confectionery Nutrition 0.000 description 10
- 230000008673 vomiting Effects 0.000 description 10
- 208000004880 Polyuria Diseases 0.000 description 9
- 206010047700 Vomiting Diseases 0.000 description 9
- 230000035619 diuresis Effects 0.000 description 9
- 210000000952 spleen Anatomy 0.000 description 9
- 206010010774 Constipation Diseases 0.000 description 8
- 208000007502 anemia Diseases 0.000 description 8
- 230000001737 promoting effect Effects 0.000 description 8
- 206010012735 Diarrhoea Diseases 0.000 description 7
- 238000001816 cooling Methods 0.000 description 7
- 208000002173 dizziness Diseases 0.000 description 7
- 206010019233 Headaches Diseases 0.000 description 6
- 206010041349 Somnolence Diseases 0.000 description 6
- 210000003238 esophagus Anatomy 0.000 description 6
- 231100000869 headache Toxicity 0.000 description 6
- 210000002216 heart Anatomy 0.000 description 6
- 230000023597 hemostasis Effects 0.000 description 6
- 210000003734 kidney Anatomy 0.000 description 6
- 206010030113 Oedema Diseases 0.000 description 5
- 244000064622 Physalis edulis Species 0.000 description 5
- 208000001647 Renal Insufficiency Diseases 0.000 description 5
- 208000003455 anaphylaxis Diseases 0.000 description 5
- 210000004027 cell Anatomy 0.000 description 5
- 238000006243 chemical reaction Methods 0.000 description 5
- 230000001939 inductive effect Effects 0.000 description 5
- 201000006370 kidney failure Diseases 0.000 description 5
- 210000002429 large intestine Anatomy 0.000 description 5
- 208000024891 symptom Diseases 0.000 description 5
- 208000011580 syndromic disease Diseases 0.000 description 5
- 206010002198 Anaphylactic reaction Diseases 0.000 description 4
- 208000006820 Arthralgia Diseases 0.000 description 4
- 206010062717 Increased upper airway secretion Diseases 0.000 description 4
- 208000000112 Myalgia Diseases 0.000 description 4
- 206010068319 Oropharyngeal pain Diseases 0.000 description 4
- 201000007100 Pharyngitis Diseases 0.000 description 4
- 206010067171 Regurgitation Diseases 0.000 description 4
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 4
- 208000006218 bradycardia Diseases 0.000 description 4
- 230000036471 bradycardia Effects 0.000 description 4
- 210000003736 gastrointestinal content Anatomy 0.000 description 4
- 206010022437 insomnia Diseases 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 210000004877 mucosa Anatomy 0.000 description 4
- 208000026435 phlegm Diseases 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 206010043554 thrombocytopenia Diseases 0.000 description 4
- 201000010000 Agranulocytosis Diseases 0.000 description 3
- 206010008479 Chest Pain Diseases 0.000 description 3
- 241000721047 Danaus plexippus Species 0.000 description 3
- 208000032843 Hemorrhage Diseases 0.000 description 3
- 206010036790 Productive cough Diseases 0.000 description 3
- 208000003251 Pruritus Diseases 0.000 description 3
- 206010037660 Pyrexia Diseases 0.000 description 3
- 208000005946 Xerostomia Diseases 0.000 description 3
- 230000036783 anaphylactic response Effects 0.000 description 3
- 206010013781 dry mouth Diseases 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 230000004438 eyesight Effects 0.000 description 3
- 210000004400 mucous membrane Anatomy 0.000 description 3
- 210000003802 sputum Anatomy 0.000 description 3
- 208000024794 sputum Diseases 0.000 description 3
- 231100000419 toxicity Toxicity 0.000 description 3
- 230000001988 toxicity Effects 0.000 description 3
- 239000003053 toxin Substances 0.000 description 3
- 231100000765 toxin Toxicity 0.000 description 3
- 210000003462 vein Anatomy 0.000 description 3
- SUBDBMMJDZJVOS-UHFFFAOYSA-N 5-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}-1H-benzimidazole Chemical compound N=1C2=CC(OC)=CC=C2NC=1S(=O)CC1=NC=C(C)C(OC)=C1C SUBDBMMJDZJVOS-UHFFFAOYSA-N 0.000 description 2
- 208000004998 Abdominal Pain Diseases 0.000 description 2
- 206010000087 Abdominal pain upper Diseases 0.000 description 2
- 206010001580 Albuminuria Diseases 0.000 description 2
- 201000004384 Alopecia Diseases 0.000 description 2
- 208000019901 Anxiety disease Diseases 0.000 description 2
- 206010015218 Erythema multiforme Diseases 0.000 description 2
- 206010018687 Granulocytopenia Diseases 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 206010020751 Hypersensitivity Diseases 0.000 description 2
- 206010020772 Hypertension Diseases 0.000 description 2
- 206010020880 Hypertrophy Diseases 0.000 description 2
- 206010028813 Nausea Diseases 0.000 description 2
- 208000005392 Spasm Diseases 0.000 description 2
- 206010042033 Stevens-Johnson syndrome Diseases 0.000 description 2
- 208000001871 Tachycardia Diseases 0.000 description 2
- 206010044223 Toxic epidermal necrolysis Diseases 0.000 description 2
- 231100000087 Toxic epidermal necrolysis Toxicity 0.000 description 2
- 102000003929 Transaminases Human genes 0.000 description 2
- 108090000340 Transaminases Proteins 0.000 description 2
- 208000024780 Urticaria Diseases 0.000 description 2
- 206010047513 Vision blurred Diseases 0.000 description 2
- 208000026935 allergic disease Diseases 0.000 description 2
- 230000007815 allergy Effects 0.000 description 2
- 231100000360 alopecia Toxicity 0.000 description 2
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 description 2
- 229910021502 aluminium hydroxide Inorganic materials 0.000 description 2
- 230000036506 anxiety Effects 0.000 description 2
- 206010003549 asthenia Diseases 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000003467 diminishing effect Effects 0.000 description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 2
- 201000006549 dyspepsia Diseases 0.000 description 2
- 206010016256 fatigue Diseases 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000007849 functional defect Effects 0.000 description 2
- 201000000079 gynecomastia Diseases 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 230000001965 increasing effect Effects 0.000 description 2
- 201000006334 interstitial nephritis Diseases 0.000 description 2
- 208000003243 intestinal obstruction Diseases 0.000 description 2
- 230000003780 keratinization Effects 0.000 description 2
- 201000002364 leukopenia Diseases 0.000 description 2
- 231100001022 leukopenia Toxicity 0.000 description 2
- 230000003908 liver function Effects 0.000 description 2
- 230000003340 mental effect Effects 0.000 description 2
- 230000008693 nausea Effects 0.000 description 2
- 230000003448 neutrophilic effect Effects 0.000 description 2
- 229960000381 omeprazole Drugs 0.000 description 2
- 210000001819 pancreatic juice Anatomy 0.000 description 2
- 244000052769 pathogen Species 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 230000003014 reinforcing effect Effects 0.000 description 2
- 230000004206 stomach function Effects 0.000 description 2
- 230000009747 swallowing Effects 0.000 description 2
- 201000000596 systemic lupus erythematosus Diseases 0.000 description 2
- 230000006794 tachycardia Effects 0.000 description 2
- 231100000331 toxic Toxicity 0.000 description 2
- 230000002588 toxic effect Effects 0.000 description 2
- 210000003932 urinary bladder Anatomy 0.000 description 2
- 230000024883 vasodilation Effects 0.000 description 2
- DWNBOPVKNPVNQG-LURJTMIESA-N (2s)-4-hydroxy-2-(propylamino)butanoic acid Chemical compound CCCN[C@H](C(O)=O)CCO DWNBOPVKNPVNQG-LURJTMIESA-N 0.000 description 1
- ASWBNKHCZGQVJV-UHFFFAOYSA-N (3-hexadecanoyloxy-2-hydroxypropyl) 2-(trimethylazaniumyl)ethyl phosphate Chemical compound CCCCCCCCCCCCCCCC(=O)OCC(O)COP([O-])(=O)OCC[N+](C)(C)C ASWBNKHCZGQVJV-UHFFFAOYSA-N 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- 208000007743 Acute Abdomen Diseases 0.000 description 1
- 206010002199 Anaphylactic shock Diseases 0.000 description 1
- 241000272814 Anser sp. Species 0.000 description 1
- 206010003011 Appendicitis Diseases 0.000 description 1
- 206010003671 Atrioventricular Block Diseases 0.000 description 1
- 208000010392 Bone Fractures Diseases 0.000 description 1
- 208000014644 Brain disease Diseases 0.000 description 1
- 206010006187 Breast cancer Diseases 0.000 description 1
- 208000026310 Breast neoplasm Diseases 0.000 description 1
- 208000009079 Bronchial Spasm Diseases 0.000 description 1
- 208000014181 Bronchial disease Diseases 0.000 description 1
- 206010006482 Bronchospasm Diseases 0.000 description 1
- 208000002881 Colic Diseases 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 241001562519 Cynodon plectostachyus Species 0.000 description 1
- 206010012289 Dementia Diseases 0.000 description 1
- 206010012373 Depressed level of consciousness Diseases 0.000 description 1
- 206010013700 Drug hypersensitivity Diseases 0.000 description 1
- 206010013887 Dysarthria Diseases 0.000 description 1
- 206010013911 Dysgeusia Diseases 0.000 description 1
- 208000032274 Encephalopathy Diseases 0.000 description 1
- 206010014950 Eosinophilia Diseases 0.000 description 1
- 206010053155 Epigastric discomfort Diseases 0.000 description 1
- 208000010228 Erectile Dysfunction Diseases 0.000 description 1
- 208000027776 Extrapyramidal disease Diseases 0.000 description 1
- 206010056325 Faecaloma Diseases 0.000 description 1
- 206010017076 Fracture Diseases 0.000 description 1
- 208000001287 Galactorrhea Diseases 0.000 description 1
- 206010017600 Galactorrhoea Diseases 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 208000034308 Grand mal convulsion Diseases 0.000 description 1
- 208000004547 Hallucinations Diseases 0.000 description 1
- 208000035186 Hemolytic Autoimmune Anemia Diseases 0.000 description 1
- 208000000857 Hepatic Insufficiency Diseases 0.000 description 1
- 206010019663 Hepatic failure Diseases 0.000 description 1
- 206010019851 Hepatotoxicity Diseases 0.000 description 1
- 206010020565 Hyperaemia Diseases 0.000 description 1
- 208000019025 Hypokalemia Diseases 0.000 description 1
- 206010021036 Hyponatraemia Diseases 0.000 description 1
- 208000029663 Hypophosphatemia Diseases 0.000 description 1
- 208000001953 Hypotension Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010024419 Libido decreased Diseases 0.000 description 1
- 206010025327 Lymphopenia Diseases 0.000 description 1
- 206010025421 Macule Diseases 0.000 description 1
- 208000019255 Menstrual disease Diseases 0.000 description 1
- 208000007101 Muscle Cramp Diseases 0.000 description 1
- 206010028391 Musculoskeletal Pain Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010029216 Nervousness Diseases 0.000 description 1
- 206010029350 Neurotoxicity Diseases 0.000 description 1
- 206010061876 Obstruction Diseases 0.000 description 1
- 206010030216 Oesophagitis Diseases 0.000 description 1
- 206010033661 Pancytopenia Diseases 0.000 description 1
- IQPSEEYGBUAQFF-UHFFFAOYSA-N Pantoprazole Chemical compound COC1=CC=NC(CS(=O)C=2NC3=CC=C(OC(F)F)C=C3N=2)=C1OC IQPSEEYGBUAQFF-UHFFFAOYSA-N 0.000 description 1
- 206010034038 Parotitis Diseases 0.000 description 1
- 102000057297 Pepsin A Human genes 0.000 description 1
- 108090000284 Pepsin A Proteins 0.000 description 1
- 102000004160 Phosphoric Monoester Hydrolases Human genes 0.000 description 1
- 108090000608 Phosphoric Monoester Hydrolases Proteins 0.000 description 1
- 208000010642 Porphyrias Diseases 0.000 description 1
- 208000001431 Psychomotor Agitation Diseases 0.000 description 1
- 208000008718 Pyuria Diseases 0.000 description 1
- 206010038743 Restlessness Diseases 0.000 description 1
- 231100000168 Stevens-Johnson syndrome Toxicity 0.000 description 1
- 208000005718 Stomach Neoplasms Diseases 0.000 description 1
- 208000009205 Tinnitus Diseases 0.000 description 1
- 238000008050 Total Bilirubin Reagent Methods 0.000 description 1
- 206010044221 Toxic encephalopathy Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 229930003270 Vitamin B Natural products 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 206010048222 Xerosis Diseases 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- PNNCWTXUWKENPE-UHFFFAOYSA-N [N].NC(N)=O Chemical compound [N].NC(N)=O PNNCWTXUWKENPE-UHFFFAOYSA-N 0.000 description 1
- 206010000059 abdominal discomfort Diseases 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000002671 adjuvant Substances 0.000 description 1
- 239000003513 alkali Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 230000006793 arrhythmia Effects 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 201000000448 autoimmune hemolytic anemia Diseases 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 210000000941 bile Anatomy 0.000 description 1
- 235000019658 bitter taste Nutrition 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000004204 blood vessel Anatomy 0.000 description 1
- 210000005098 blood-cerebrospinal fluid barrier Anatomy 0.000 description 1
- 210000001185 bone marrow Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000000747 cardiac effect Effects 0.000 description 1
- 238000002512 chemotherapy Methods 0.000 description 1
- 229940099352 cholate Drugs 0.000 description 1
- BHQCQFFYRZLCQQ-OELDTZBJSA-N cholic acid Chemical compound C([C@H]1C[C@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)[C@@H](O)C1 BHQCQFFYRZLCQQ-OELDTZBJSA-N 0.000 description 1
- 208000037976 chronic inflammation Diseases 0.000 description 1
- 208000037893 chronic inflammatory disorder Diseases 0.000 description 1
- 208000020832 chronic kidney disease Diseases 0.000 description 1
- 208000022831 chronic renal failure syndrome Diseases 0.000 description 1
- 229960001380 cimetidine Drugs 0.000 description 1
- CCGSUNCLSOWKJO-UHFFFAOYSA-N cimetidine Chemical compound N#CNC(=N/C)\NCCSCC1=NC=N[C]1C CCGSUNCLSOWKJO-UHFFFAOYSA-N 0.000 description 1
- 230000001447 compensatory effect Effects 0.000 description 1
- 208000004209 confusion Diseases 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 206010061428 decreased appetite Diseases 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 230000001079 digestive effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 206010013395 disorientation Diseases 0.000 description 1
- 229960001253 domperidone Drugs 0.000 description 1
- FGXWKSZFVQUSTL-UHFFFAOYSA-N domperidone Chemical compound C12=CC=CC=C2NC(=O)N1CCCN(CC1)CCC1N1C2=CC=C(Cl)C=C2NC1=O FGXWKSZFVQUSTL-UHFFFAOYSA-N 0.000 description 1
- 201000005311 drug allergy Diseases 0.000 description 1
- 208000001848 dysentery Diseases 0.000 description 1
- 235000019564 dysgeusia Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000000222 eosinocyte Anatomy 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 210000003743 erythrocyte Anatomy 0.000 description 1
- 208000006881 esophagitis Diseases 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 208000011318 facial edema Diseases 0.000 description 1
- 229960001596 famotidine Drugs 0.000 description 1
- XUFQPHANEAPEMJ-UHFFFAOYSA-N famotidine Chemical compound NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1 XUFQPHANEAPEMJ-UHFFFAOYSA-N 0.000 description 1
- 210000003754 fetus Anatomy 0.000 description 1
- 206010016766 flatulence Diseases 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 206010017758 gastric cancer Diseases 0.000 description 1
- 210000004051 gastric juice Anatomy 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 210000003714 granulocyte Anatomy 0.000 description 1
- 208000019622 heart disease Diseases 0.000 description 1
- 208000024798 heartburn Diseases 0.000 description 1
- 208000006750 hematuria Diseases 0.000 description 1
- 208000007475 hemolytic anemia Diseases 0.000 description 1
- 230000007686 hepatotoxicity Effects 0.000 description 1
- 231100000304 hepatotoxicity Toxicity 0.000 description 1
- 239000003485 histamine H2 receptor antagonist Substances 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 230000036543 hypotension Effects 0.000 description 1
- 201000001881 impotence Diseases 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000011221 initial treatment Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 230000003907 kidney function Effects 0.000 description 1
- 230000006651 lactation Effects 0.000 description 1
- 230000001983 lactogenic effect Effects 0.000 description 1
- 229960003174 lansoprazole Drugs 0.000 description 1
- MJIHNNLFOKEZEW-UHFFFAOYSA-N lansoprazole Chemical compound CC1=C(OCC(F)(F)F)C=CN=C1CS(=O)C1=NC2=CC=CC=C2N1 MJIHNNLFOKEZEW-UHFFFAOYSA-N 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 206010024378 leukocytosis Diseases 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 230000005976 liver dysfunction Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 210000000111 lower esophageal sphincter Anatomy 0.000 description 1
- 231100001023 lymphopenia Toxicity 0.000 description 1
- 210000001595 mastoid Anatomy 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 229960004503 metoclopramide Drugs 0.000 description 1
- TTWJBBZEZQICBI-UHFFFAOYSA-N metoclopramide Chemical compound CCN(CC)CCNC(=O)C1=CC(Cl)=C(N)C=C1OC TTWJBBZEZQICBI-UHFFFAOYSA-N 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 231100000228 neurotoxicity Toxicity 0.000 description 1
- 230000007135 neurotoxicity Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 229960005019 pantoprazole Drugs 0.000 description 1
- 208000035824 paresthesia Diseases 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 229940111202 pepsin Drugs 0.000 description 1
- 208000028591 pheochromocytoma Diseases 0.000 description 1
- 230000007096 poisonous effect Effects 0.000 description 1
- 208000024896 potassium deficiency disease Diseases 0.000 description 1
- 230000035935 pregnancy Effects 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 229960004157 rabeprazole Drugs 0.000 description 1
- YREYEVIYCVEVJK-UHFFFAOYSA-N rabeprazole Chemical compound COCCCOC1=CC=NC(CS(=O)C=2NC3=CC=CC=C3N=2)=C1C YREYEVIYCVEVJK-UHFFFAOYSA-N 0.000 description 1
- 230000008085 renal dysfunction Effects 0.000 description 1
- 208000023504 respiratory system disease Diseases 0.000 description 1
- 206010039083 rhinitis Diseases 0.000 description 1
- 230000000630 rising effect Effects 0.000 description 1
- 201000005404 rubella Diseases 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 230000000391 smoking effect Effects 0.000 description 1
- 210000005070 sphincter Anatomy 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 230000035922 thirst Effects 0.000 description 1
- 231100000886 tinnitus Toxicity 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 210000001186 vagus nerve Anatomy 0.000 description 1
- 208000029257 vision disease Diseases 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- 210000004916 vomit Anatomy 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a preparation method of a traditional Chinese medicine for treating pharyngalgia type reflux esophagitis and belongs to the technical field of the preparation method of the traditional Chinese medicine. The existing medicine for treating the pharyngalgia type reflux esophagitis is primarily ranitidine with contraindications for the people which are allergic to the medicine and other H2 receptors, pregnant women and breast feeding women. The technical scheme of the invention is as follows: the preparation method comprises the following steps of: putting and soaking 26 traditional Chinese medicines consisting of umbellate rockjasmine herb or fruit, orpine, fruticose breynia juvenile branchlet and leaf, hastate phymatopsis herb with root, blackberry lily, puffball (cloth bag), chinese lantern-plant, subprostrate sophora, Chinese white olive, manyleaf paris rhizome, diversecolor cinquefoil, radix berberidis, sticktight, Japanese cayratia herb, tuopangen, radix stellariae dichotomae, wood sorrel, ceanothus, villosulous veronicastrum herb or root, daghestan sweetclover herb, coffee senna, common alstonia bark or leaf, lophatherum gracile, mung bean, chrysanthemum and liquorice in water, decocting with slow fire, and filtering to remove the slag for co-decocting liquid medicine, wherein the decocted liquid medicine is the traditional Chinese medicine for treating the pharyngalgia type reflux esophagitis. The preparation method has the advantages that the prepared traditional Chinese liquid medicine is small in side effect, short in treatment course, high in recovery rate and capable of avoiding adverse reactions caused by antibacterial agents of Western medicine.
Description
Technical field
The present invention relates to the Chinese medicinal preparation method technical field, more specifically a kind of Chinese medicinal preparation method for the treatment of pharyngalgia type reflux esophagitis.
Background technology
Current treatment pharyngalgia type reflux esophagitis, the general employing: 1, ranitidine: 1. contraindication: to this medicine and other H
2receptor antagonist allergy sufferers, anemia of pregnant woman, women breast-feeding their children, the forbidding of child below 8 years old.2. be cautious use of: liver, renal insufficiency person, acute hematoporphyria person, old people are cautious use of.3. can occur headache, dizzy, weak, obnubilation, mental act extremely, insomnia etc.; The mental symptoms such as disorientation, drowsiness, anxiety, appear in liver, renal insufficiency person and gerontal patient after accidental taking medicine; A small amount of generation blurred vision is arranged; Constipation, diarrhoea occur, feel sick, vomit, suffer from abdominal pain; Erythra can occur, only a few generation erythema multiforme is arranged; Rare arthralgia, myalgia; Rare anaphylactic reaction, show as rubella, vasodilation, heating, bronchospasm, hypotension, anaphylactic shock, chest pain etc.; Life-time service can cause vitamin B
12lack, male breast is womanlike rare; Cause that renal dysfunction etc., quiet notes rear section patient fever sensation of the face sense, dizziness can occur, feel sick, perspiration and gastric irritation.4. this medicine has certain toxicity to liver, therefore, in the administration process, should monitor patient's changes of liver function.When 5. vein gives this medicine, bradycardia can appear.Therefore should be slow during quiet notes, and should make regular check on electrocardiogram in the medication process.6. this medicine has certain inhibitory action to bone marrow, and the moderate leukocyte of reversibility or granulocytopenia can occur small number of patients, also occur thrombocytopenia and autoimmune hemolytic anemia.2, aluminium hydroxide: 1. contraindication: strong basicity digestive juice secretion deficiency or acatharsia person, fracture patient, the hypophosphatemia patient such as bile, pancreatic juice are arranged and the aluminium hydroxide allergy sufferers is forbidden.2. be cautious use of: the Acute Abdomens such as renal insufficiency person, prolonged constipation person, old people, appendicitis are cautious use of.3. can cause nausea, the symptom such as vomiting, constipation.Take in a large number for a long time, can cause serious constipation, even the coproma piece causes intestinal obstruction.4. the chronic renal failure patients long-term taking can cause encephalopathy, dementia and small cell anemia etc.3, omeprazole: 1. contraindication: those who are allergic to this drug, severe renal functional defect person, anemia of pregnant woman, infant patient's forbidding.2. be cautious use of: liver, renal insufficiency person, women breast-feeding their children, gerontal patient should be cautious use of.3. common adverse reactions be diarrhoea, headache, feel sick, stomachache, flatulence and constipation, accidental serum aminotransferase increases, erythra, dizzy, drowsiness, insomnia etc.; Visible chest pain, cardiopalmus, tachycardia or excessively slow, hypertension, periphery edema.Visible microscopic pyuria, albuminuria, hematuria, frequent micturition, urinary system infection, interstitial nephritis, glucose in urine, orchiodynia.Visible hemolytic anemia.Visible erubescence, drying.Rare heliosensitivity, erythema multiforme, Stevens Johnson syndrome, toxicity epidermal necrolysis, alopecia.Rare blurred vision.Rare perspiration increases, hyponatremia, gynecomastia.Rare arthralgia, myalgia, muscular strength weaken.Rare leukopenia, thrombocytopenia, agranulocytosis and pancytopenia.4, cimetidine: 1. contraindication: anemia of pregnant woman, women breast-feeding their children's forbidding.2. be cautious use of: serious heart and respiratory system disease, chronic inflammatory disease are cautious use of as systemic lupus erythematosus (sle) (SLE), encephalosis, renal function injury, hepatic insufficiency, child.3. more common untoward reaction has diarrhoea, dizziness, weak, headache and erythra etc.; Can cause gynaecomastia, women's galactorrhea, hyposexuality, sexual impotence, sperm count minimizing etc. when the useful agents amount is larger, can pass through blood-cerebrospinal fluid barrier, there is certain neurotoxicity.Accidental abalienation, the untoward reaction that this product is rare has: anaphylaxis, heating, arthralgia, myalgia, granulocytopenia, thrombocytopenia, interstitial nephritis, hepatotoxicity, bradycardia, tachycardia etc.5, rabeprazole: 1. contraindication: anemia of pregnant woman, women breast-feeding their children's forbidding.2. be cautious use of: anaphylaxis or other untoward reaction persons, the patient of liver dysfunction once occurred while previously using the medicine such as lansoprazole, omeprazole, pantoprazole, the gerontal patient should be cautious use of this medicine.3. visible light-sensitive reaction, erythra, pruritus, edema, visual disorder, myalgia, rhinitis.Visible xerostomia, abdominal distention, stomachache, accidentally feel sick, vomiting, constipation, diarrhoea.Rare cardiopalmus, bradycardia, chest pain.Visible dizzy, limbs fatigue, insensitive, accidental headache, rare insomnia, sleepy, grip are low, inarticulateness, lurch.Accidental blood urea nitrogen raises, albuminuria.4. use this medicine can cause erythrocyte, lymphopenia, leukopenia or increase the symptoms such as eosinophilic granulocyte, neutrophilic leukocytosis.5. use this medicine can cause the phenomenons such as propylhomoserin aminotransferase, AST, alkali phosphatase total bilirubin, T-CHOL rising.6. use this medicine likely to cover the gastric cancer symptom, therefore should on the basis of getting rid of malignant tumor, use this medicine.6, domperidone: 1. contraindication: Patients With Pheochromocytoma, patient with breast cancer, mechanical intestinal obstruction patient, gastrointestinal hemorrhage patient and anemia of pregnant woman's forbidding.2. be cautious use of: 1 years old Infants Below, allergic constitution person, cardiac or hypokalemia patient and the tumor patient of accepting chemotherapy are cautious use of.3. accidental headache, dizziness, drowsiness, asthenia, nervousness etc., extrapyramidal symptoms, epilepsy etc., visible abdominal cramps pain, xerostomia, diarrhoea; Use larger dose can cause the non-lactation period lactogenic, arrhythmia can occur, accidental evanescent eruption or pruritus.7, famotidine: 1. contraindication: those who are allergic to this drug, severe renal functional defect person, anemia of pregnant woman, women breast-feeding their children's forbidding.2. be cautious use of: have drug allergy history, liver, renal insufficiency person, infant to be cautious use of.3. can cause constipation, nausea,vomiting,diarrhea, abdominal discomfort, xerostomia, inappetence, parotitis and dysgeusia; Period in a medicine, the detection index of liver function can raise; Most headache, rare have dizziness, confusion, anxiety, paraesthesia, depression, insomnia, general lassitude is unable and drowsiness etc., and rare neutrophilic granulocyte reduces and thrombocytopenia, the eosinophilia, and rare libido reduces; Rare erythra, urticaria, alopecia, acne, pruritus, xerosis cutis and flushing; Rare cardiopalmus, bradycardia, atrioventricular block, increased blood pressure, menoxenia, answer monitor ECG to change during medication; Rare toxic epidermal necrolysis; Rare hallucination, epilepsy grand mal, medication should be noted the patient clinical performance; Can cause tinnitus; Musculoskeletal pain, comprise muscle cramp and arthralgia; Can cause pars orbitalis edema, facial edema, conjunctival congestion, vasodilation, drug fever, urticaria and erythra etc.8, metoclopramide: can cause that drowsiness, weak, extrapyramidal system syndrome and spirit are uneasy etc.Not yet clear and definite on the fetus impact, thus should not be for vomiting during pregnancy, and the anemia of pregnant woman is cautious use of.
Summary of the invention
For overcoming above-mentioned shortcoming, the objective of the invention is to invent a kind of Chinese medicinal preparation method for the treatment of pharyngalgia type reflux esophagitis.
Pharyngalgia type reflux esophagitis refers to cause the inflammation of distal esophagus mucosa due to stomach or the anti-esophagus that flows into of intestinal contents." Medical Treasures of the Golden Chamber " is called regurgitation.In " vomiting sound of vomiting diarrhea disease ", point out: " eating in the morning but vomiting out in the evening, vomiting out in the morning what eaten at last night, indigested food stagnated in the stomach, name is said regurgitation ".Its card be eat after, stop in stomach and do not change, towards trencherman's vomiting at night, declining trencherman is towards telling, " Jing Yue's complete work is dysphagic " said: " regurgitation person, eat still can enter, and enters and instead go out, therefore say regurgitation.
etiology and pathogenesis:it is the higher-pressure region of long 2～5 centimetres that lower esophageal is crossed diaphragm segment, and this place's pressure is high at the bottom of than stomach, though it plays the barrier action of sphincter sample anatomically without sphincteral structure between the esophagus stomach function regulating, therefore be called lower esophageal sphincter.When intragastric pressure increases, the pressure of LES is also along with increasing, to avoid stomach, the anti-esophagus that flows into of intestinal contents.LES is subject to the adjusting of vagus nerve and hormone.Drink, smoking, all can make the miopragia of LES, cause the anti-esophagus that flows to of gastrointestinal contents.So the hydrochloric acid in gastric juice and pepsin, the cholate in gallbladder, pancreatic juice and LYSOLECITHIN SUNLECITHIN A etc. can be damaged mucous membrane of esophagus, cause esophagitis.Mucous membrane of esophagus be subject to counter flow thing infringement after, the squamous cell on mucosa top layer comes off, and the basal layer cell hypertrophy, thickens, and produces more new cell with the compensatory cells of superficial layer come off, therefore jejune epithelial increasing proportion in mucosa.In addition, blood vessel mastoid process hypertrophy, blood tube bundle and the teleneuron of following extend, and even can reach the surface of epithelium.Due to these changes, the visible mucous membrane of esophagus of endoscope is hyperemia, edema, crisp and easy hemorrhage, rotten to the corn, shallow table ulcer, or, with exudate, mucosa is graininess sometimes, or white macula is arranged.Innate excess of YANG in the body, pathogenic heat is attacked, and causes primary disease.
clinical manifestation:the pharyngalgia weight.Under normal circumstances, Esophagus has the keratinization top layer, the epithelial cell attenuation on keratinization top layer or come off fully, heart burn.Burn feeling can involve to neck, interscapular region, ear, two upper arm even, and Chang Yu occurs after the meal soon, or, strenuous exercise anteflexion at trunk, lies on the back or occur during lateral position.Instead flow than severe one, when trunk is anteflexion or lie in bed, often have the stomach of acidity or bitterness or intestinal contents to overflow into oral cavity.Along with the progress of the course of disease, the burn feeling attack times reduces, and engenders acataposis.The intermittent obstruction sense is arranged when swallowing food, and severe one can be with swallowing pain.Red tongue, yellow fur, rapid pulse.
its technical scheme:get Herba Androsaces umbellatae 6 weight portions, Herba hylotelephii erythrosticti 3 weight portions, Folium et cacumen Breyniae Fruticosae 3 weight portions, Phymatopsis hastata (Thunb.) Kitag. 5 weight portions, Rhizoma Belamcandae 3 weight portions, Lasiosphaera Seu Calvatia 5 weight portions (cloth bag), Calyx Seu Fructus Physalis 2 weight portions, Radix Sophorae Tonkinensis 6 weight portions, Fructus Canarii 3 weight portions, Rhizoma Paridis 1 weight portion, Herba Potentillae Discoloris 4 weight portions, Radix Berberidis 5 weight portions, Herba Bidentis Bipinnatae 4 weight portions, Herba Cayatiae Japonicae 3 weight portions, TUOPANGEN 2 weight portions, Radix Stellariae 6 weight portions, Herba Oxalidis Corniculatae 6 weight portions, Fructus rhamni (Rhamnus davurica Pall.) 6 weight portions, Herba veronicastri villosuli 6 weight portions, Herba Meliloti Suaveolentis 3 weight portions, Herba cassiae occidentalis 6 weight portions, Cortex Alstoniae scholaris 6 weight portions, Herba Lophatheri 12 weight portions, Semen phaseoli radiati 18 weight portions, Flos Chrysanthemi 12 weight portions and Radix Glycyrrhizae 9 weight portions, above 26 flavor Chinese medicines are put into to 1500 ml waters, soak 30 minutes, then slow fire is fried 30 minutes, boil medicine altogether 360 milliliters of liquid of filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of pharyngalgia type reflux esophagitis.
the advantage of this invention:we's 26 flavor Chinese medicines, all can buy in pharmacy, makes simply, and the herb liquid toxic and side effects of making is little, short treating period, and cure rate is high.Monarch, just right.In the time of application Chinese medicine, untoward reaction, anaphylaxis and the toxic reaction of having avoided the Western medicine antibacterials to cause.Herba Androsaces umbellatae, Herba hylotelephii erythrosticti, Folium et cacumen Breyniae Fruticosae, Phymatopsis hastata (Thunb.) Kitag., Rhizoma Belamcandae, Lasiosphaera Seu Calvatia, Calyx Seu Fructus Physalis, Radix Sophorae Tonkinensis, Fructus Canarii, Rhizoma Paridis, Herba Potentillae Discoloris, Radix Berberidis, Herba Bidentis Bipinnatae, Herba Cayatiae Japonicae, TUOPANGEN, above 15 flavor medical instruments have resolving toxin and disinhibiting the throat, heat-clearing and toxic substances removing, the effect of reducing swelling and alleviating pain, cooling blood for hemostasis, vanishing sputum and dispelling knot, removing toxic substances and promoting subsidence of swelling, lowering the adverse-rising QI to resolve phlegm.In the process for the treatment of pharyngalgia type reflux esophagitis, play the primary treatment effect, therefore be monarch drug.Radix Stellariae, Herba Oxalidis Corniculatae, Fructus rhamni (Rhamnus davurica Pall.), Herba veronicastri villosuli, Herba Meliloti Suaveolentis, Herba cassiae occidentalis, Cortex Alstoniae scholaris, Herba Lophatheri, Semen phaseoli radiati, above 9 flavor medical instruments have the effect of heat clearing and damp drying, eliminating fire and detoxication, cooling blood for hemostasis, reducing swelling and alleviating pain, clearing away heat-damp and promoting diuresis, eliminating stasis to stop pain.In the process for the treatment of pharyngalgia type reflux esophagitis, can assist principal agent performance therapeutical effect, therefore be ministerial drug.Flos Chrysanthemi: be slightly cold; Sweet, bitter; Return lung, Liver Channel.Dispelling wind and heat pathogens, the suppressing the hyperactive liver improving eyesight.The through focus of all medicines of this flavor medicine energy rate, therefore be adjuvant drug.Radix Glycyrrhizae: sweet, flat.Enter 12 warps.The spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.Can entangle the bias of all medicines, can alleviate again the toxicity of all medicines, therefore for making medicine.Herba Androsaces umbellatae, Herba hylotelephii erythrosticti, Folium et cacumen Breyniae Fruticosae, Phymatopsis hastata (Thunb.) Kitag., Rhizoma Belamcandae, Lasiosphaera Seu Calvatia, Calyx Seu Fructus Physalis, Radix Sophorae Tonkinensis, Fructus Canarii, Rhizoma Paridis, Herba Potentillae Discoloris, Radix Berberidis, Herba Bidentis Bipinnatae, Herba Cayatiae Japonicae, TUOPANGEN, Radix Stellariae, Herba Oxalidis Corniculatae, Fructus rhamni (Rhamnus davurica Pall.), Herba veronicastri villosuli, Herba Meliloti Suaveolentis, Herba cassiae occidentalis, Cortex Alstoniae scholaris, Herba Lophatheri, Semen phaseoli radiati, Flos Chrysanthemi, Radix Glycyrrhizae, above 26 flavor medicines, there is resolving toxin and disinhibiting the throat, heat-clearing and toxic substances removing, the effect of reducing swelling and alleviating pain, cooling blood for hemostasis, vanishing sputum and dispelling knot, removing toxic substances and promoting subsidence of swelling, eliminating fire and detoxication, eliminating stasis to stop pain.Monarch, compatibility is proper, is the optimum formula for the treatment of pharyngalgia type reflux esophagitis.Herba Androsaces umbellatae: hot, bitter, be slightly cold.Enter lung, liver, spleen channel.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Herba hylotelephii erythrosticti: bitter, sour, cold.Enter the heart, liver, kidney, large intestine channel, heat-clearing and toxic substances removing, cooling blood for hemostasis.Folium et cacumen Breyniae Fruticosae: hardship, cold.Enter large intestine, Liver Channel.Heat-clearing and toxic substances removing, removing stasis to stop bleeding.Goose slaps full star grass: hardship, and cool.Enter lung, liver, kidney channel.Heat-clearing and toxic substances removing, reducing heat in the blood and treating stranguria.Rhizoma Belamcandae: hardship, cold.Enter lung, Liver Channel.Resolving toxin and disinhibiting the throat, vanishing sputum and dispelling knot.Lasiosphaera Seu Calvatia (cloth bag): suffering, flat.Enter lung meridian.Removing heat from the lung and relieving sorethroat, removing toxic substances and promoting subsidence of swelling, astringing to arrest bleeding.Calyx Seu Fructus Physalis: bitter, sour, cold.Enter the heart, lung, kidney, urinary bladder channel.Heat-clearing and toxic substances removing, relieving sore throat and diminishing swelling, lowering the adverse-rising QI to resolve phlegm, inducing diuresis for treating stranguria syndrome.Radix Sophorae Tonkinensis: hardship, cold.Enter the heart, lung, stomach warp.Heat-clearing and toxic substances removing, relieving sore throat and diminishing swelling.Fructus Canarii: sweet, puckery, sour, flat.Enter lung meridian.Removing heat from the lung and relieving sorethroat, removing toxic substances.Rhizoma Paridis: micro-hardship, cool.Slightly poisonous.Enter Liver Channel, heat-clearing and toxic substances removing, mass dissipating and swelling eliminating.Herba Potentillae Discoloris: sweet, micro-hardship, flat.Enter liver, spleen, large intestine channel.Heat-clearing and toxic substances removing, cooling blood for hemostasis.Radix Berberidis: hardship, cold.Enter lung, liver, large intestine channel.Heat-clearing and toxic substances removing, the bowel relieving dysentery relieving.Herba Bidentis Bipinnatae: hardship is slightly cold.Enter lung, famous scenic spot, stomach, large intestine channel.Heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, bowel relieving antidiarrheal.Herba Cayatiae Japonicae: sour, bitter, cold.Enter liver, spleen, urinary bladder channel.Heat-clearing and toxic substances removing, removing heat from blood detumescence, diuresis.TUOPANGEN: bitter, hot, micro-sweet, cool.Enter lung, Liver Channel.Clearing away heat and cooling blood, removing toxic substances and promoting subsidence of swelling.Radix Stellariae: sweet, bitter, be slightly cold.Enter liver, stomach warp.Reducing the asthenic fever, asthenia, clearing heat in indigestion.Herba Oxalidis Corniculatae: sour, micro-puckery, cold.Enter lung, stomach warp.Clearing away heat-damp and promoting diuresis, subduing swelling and detoxicating, cooling blood for hemostasis.Fructus rhamni (Rhamnus davurica Pall.): sweet, bitter, cold.Enter liver,kidney,spleen three warps.Clearing away heat-damp and promoting diuresis, invigorating the spleen for dissipating phlegm.Herba veronicastri villosuli: hot, bitter, cold.Enter liver, lung, kidney three warps.Heat-clearing and toxic substances removing, the capable water of dampness removing, eliminating stasis to stop pain.Herba Meliloti Suaveolentis: hot, bitter, cool, nontoxic.Enter liver, spleen, stomach warp.Heat-clearing and toxic substances removing, heat clearing and damp drying, inducing diuresis for treating stranguria syndrome.Herba cassiae occidentalis: hardship, cold.Enter lung, liver, stomach warp.Relieving cough and asthma, liver heat removing and eyesight improving, stomach function regulating help digestion, subduing swelling and detoxicating, inducing diuresis for treating stranguria syndrome, relieving constipation by purgation.Cortex Alstoniae scholaris: bitter, light, cold.Enter lung, Liver Channel.Heat-clearing and toxic substances removing, hemostasia and detumescence.Herba Lophatheri: sweet, light, cold.Enter the heart, stomach, kidney, small intestine meridian.Relieving restlessness, heat-clearing and toxic substances removing, inducing diuresis for treating stranguria syndrome, Qinghua heat-phlegm clear away heart-fire.Semen phaseoli radiati: sweet, cold.Enter the heart, spleen, stomach, lung meridian.Heat-clearing and toxic substances removing, relieve heat and thirst, inducing diuresis to remove edema, QI invigorating skin moistening, the thick intestinal of clearing stomach.Flos Chrysanthemi: be slightly cold; Sweet, bitter; Return lung, Liver Channel.Dispelling wind and heat pathogens, the suppressing the hyperactive liver improving eyesight.Radix Glycyrrhizae: sweet, flat.Enter 12 warps.Spleen reinforcing lung moistening, Yiqi and vein recovery, relieving spasm to stop pain, heat-clearing and toxic substances removing, the mediation property of medicine.
The specific embodiment
Get Herba Androsaces umbellatae 6g, Herba hylotelephii erythrosticti 3g, Folium et cacumen Breyniae Fruticosae 3g, Phymatopsis hastata (Thunb.) Kitag. 5g, Rhizoma Belamcandae 3g, Lasiosphaera Seu Calvatia 5g(cloth bag), Calyx Seu Fructus Physalis 2g, Radix Sophorae Tonkinensis 6g, Fructus Canarii 3g, Rhizoma Paridis 1g, Herba Potentillae Discoloris 4g, Radix Berberidis 5g, Herba Bidentis Bipinnatae 4g, Herba Cayatiae Japonicae 3g, TUOPANGEN 2g, Radix Stellariae 6g, Herba Oxalidis Corniculatae 6g, Fructus rhamni (Rhamnus davurica Pall.) 6g, Herba veronicastri villosuli 6g, Herba Meliloti Suaveolentis 3g, Herba cassiae occidentalis 6g, Cortex Alstoniae scholaris 6g, Herba Lophatheri 12g, Semen phaseoli radiati 18g, Flos Chrysanthemi 12g and Radix Glycyrrhizae 9g, above 26 flavor medicines are put into 1500 ml waters together, soak 30 minutes, then slow fire is fried 30 minutes, filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of pharyngalgia type reflux esophagitis.Boil medicine altogether 360 milliliters of liquid, when the client need treatment of pharyngalgia type reflux esophagitis, making fluid temperature is 36 ℃, each 120 milliliters, oral, every day three times, within 2nd, be a course for the treatment of, if symptom is still deposited, then took for second course for the treatment of, so that recovery from illness.
In 388 routine pharyngalgia type patients with reflux esophagitis, male's 275 examples, account for 70.88%; Women's 113 examples, account for 29.12%.The male is more than the women.
The range of age of table one, 388 routine pharyngalgia type patients with reflux esophagitis
| Age (year) | 19～20 | 21～30 | 31～50 | 51～58 |
| Number of cases | 15 | 218 | 152 | 3 |
| Percentage ratio | 3.87% | 56.19% | 39.17% | 0.77% |
Table two, 388 routine pharyngalgia type patients with reflux esophagitis curative effect tables
| Curative effect | Cure | Take a turn for the better | Invalid |
| Number of cases | 386 | 2 | Nothing |
| Percentage ratio | 99.48% | 0.52% | Nothing |
Table three, the 388 routine pharyngalgia type patients with reflux esophagitis tables course for the treatment of
| The treatment natural law | 3～5 | 6～9 | 10～13 | 14～22 |
| Number of cases | 13 | 272 | 96 | 7 |
| Percentage ratio | 3.35% | 70.10% | 24.75% | 1.8% |
Information slip before and after table four, 388 routine pharyngalgia type patients with reflux esophagitis treatments
Claims (1)
1. a Chinese medicinal preparation method for the treatment of pharyngalgia type reflux esophagitis, it is characterized in that: get Herba Androsaces umbellatae 6 grams, Herba hylotelephii erythrosticti 3 grams, Folium et cacumen Breyniae Fruticosae 3 grams, Phymatopsis hastata (Thunb.) Kitag. 5 grams, Rhizoma Belamcandae 3 grams, Lasiosphaera Seu Calvatia 5 grams (cloth bag), Calyx Seu Fructus Physalis 2 grams, Radix Sophorae Tonkinensis 6 grams, Fructus Canarii 3 grams, Rhizoma Paridis 1 gram, Herba Potentillae Discoloris 4 grams, Radix Berberidis 5 grams, Herba Bidentis Bipinnatae 4 grams, Herba Cayatiae Japonicae 3 grams, TUOPANGEN 2 grams, Radix Stellariae 6 grams, Herba Oxalidis Corniculatae 6 grams, Fructus rhamni (Rhamnus davurica Pall.) 6 grams, Herba veronicastri villosuli 6 grams, Herba Meliloti Suaveolentis 3 grams, Herba cassiae occidentalis 6 grams, Cortex Alstoniae scholaris 6 grams, Herba Lophatheri 12 grams, Semen phaseoli radiati 18 grams, Flos Chrysanthemi 12 grams and Radix Glycyrrhizae 9 grams, above 26 flavor Chinese medicines are put into to 1500 ml waters, soak 30 minutes, then slow fire is fried 30 minutes, boil medicine altogether 360 milliliters of liquid of filter and remove residue, fried medicinal liquid is the Chinese medicine for the treatment of pharyngalgia type reflux esophagitis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310050488.4A CN103110840B (en) | 2013-02-15 | 2013-02-15 | Preparation method of traditional Chinese medicine for treating pharyngalgia type reflux esophagitis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310050488.4A CN103110840B (en) | 2013-02-15 | 2013-02-15 | Preparation method of traditional Chinese medicine for treating pharyngalgia type reflux esophagitis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103110840A true CN103110840A (en) | 2013-05-22 |
| CN103110840B CN103110840B (en) | 2014-04-09 |
Family
ID=48409247
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310050488.4A Expired - Fee Related CN103110840B (en) | 2013-02-15 | 2013-02-15 | Preparation method of traditional Chinese medicine for treating pharyngalgia type reflux esophagitis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103110840B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251835A (en) * | 2013-05-25 | 2013-08-21 | 淄博职业学院 | Preparation method of traditional Chinese medicine for treating cardia inflammation induced by improper diet |
| CN103251838A (en) * | 2013-05-25 | 2013-08-21 | 刘国利 | Preparation method of traditional Chinese medicine for treating cardia inflammation induced by addiction to chillies |
| CN103251834A (en) * | 2013-05-25 | 2013-08-21 | 顾克峰 | Preparation method of traditional Chinese medicine for treating cardia inflammation induced by addiction to fresh gingers |
| CN104027790A (en) * | 2014-07-09 | 2014-09-10 | 郭振华 | A traditional Chinese medicine particle for treating hiatus hernia merged with reflux esophagitis and preparation method of traditional Chinese medicine particle |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102188594A (en) * | 2011-05-03 | 2011-09-21 | 王爱芹 | Preparation method of traditional Chinese medicine for treating pharyngalgia pediatric influenza |
| CN102813847A (en) * | 2012-08-03 | 2012-12-12 | 王兴福 | Preparation method of traditional Chinese medicine for treating sore throat type acute glomerulonephritis |
-
2013
- 2013-02-15 CN CN201310050488.4A patent/CN103110840B/en not_active Expired - Fee Related
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102188594A (en) * | 2011-05-03 | 2011-09-21 | 王爱芹 | Preparation method of traditional Chinese medicine for treating pharyngalgia pediatric influenza |
| CN102813847A (en) * | 2012-08-03 | 2012-12-12 | 王兴福 | Preparation method of traditional Chinese medicine for treating sore throat type acute glomerulonephritis |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103251835A (en) * | 2013-05-25 | 2013-08-21 | 淄博职业学院 | Preparation method of traditional Chinese medicine for treating cardia inflammation induced by improper diet |
| CN103251838A (en) * | 2013-05-25 | 2013-08-21 | 刘国利 | Preparation method of traditional Chinese medicine for treating cardia inflammation induced by addiction to chillies |
| CN103251834A (en) * | 2013-05-25 | 2013-08-21 | 顾克峰 | Preparation method of traditional Chinese medicine for treating cardia inflammation induced by addiction to fresh gingers |
| CN104027790A (en) * | 2014-07-09 | 2014-09-10 | 郭振华 | A traditional Chinese medicine particle for treating hiatus hernia merged with reflux esophagitis and preparation method of traditional Chinese medicine particle |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103110840B (en) | 2014-04-09 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102366615B (en) | Preparation method of traditional Chinese medicine used for treating gastritis caused by insufficiency of spleen-yang | |
| CN103263584A (en) | Preparation method of traditional Chinese medicine for treating scanty-dark-urine-type cardia inflammation | |
| CN103110896B (en) | Preparation method of traditional Chinese medicine for treating blood stasis type reflux oesophagitis | |
| CN103251808A (en) | Preparation method of traditional Chinese medicine for treating cardia inflammation induced by addiction to high-calorie food | |
| CN103251810A (en) | Preparation method of traditional Chinese medicine for treating cardia inflammation induced by heat toxins | |
| CN103110840B (en) | Preparation method of traditional Chinese medicine for treating pharyngalgia type reflux esophagitis | |
| CN103251834A (en) | Preparation method of traditional Chinese medicine for treating cardia inflammation induced by addiction to fresh gingers | |
| CN102366614B (en) | Preparation method of traditional Chinese medicine for treating pathogenic cold stomach invading type gastritis | |
| CN103120770B (en) | Preparation method of traditional Chinese medicine for treating constipation-predominant reflux esophagitis | |
| CN102366525B (en) | Method for preparing traditional Chinese medicine for treating liver-qi attacking stomach type gastritis | |
| CN103110821B (en) | Preparation method of traditional Chinese medicine for treating chili eating type reflux oesophagitis | |
| CN103239645A (en) | Preparation method of traditional Chinese medicine for treating cardia inflammation caused by excessive drinking | |
| CN103251836A (en) | Preparation method of traditional Chinese medicine for treating cardia inflammation induced by addiction to green onions | |
| CN103230504A (en) | Preparation method of traditional Chinese medicine for treating food-intake pain-type cardia inflammation | |
| CN103251807A (en) | Preparation method of traditional Chinese medicine for treating cardia inflammation induced by pathogenic fire derived from depression of liver | |
| CN102366592B (en) | Preparation method of traditional Chinese medicine for treatment of diet stagnation type gastritis | |
| CN103110898A (en) | Preparation method of traditional Chinese medicine for treating heat toxicity type reflux oesophagitis | |
| CN102366524B (en) | Preparation method of traditional Chinese medicine used for treating gastritis caused by stagnation-heat in liver and stomach | |
| CN102366549B (en) | Preparation method of traditional Chinese medicine used for treating gastritis caused by deficiency of stomach-yin | |
| CN103110901B (en) | Preparation method of traditional Chinese medicine for treating liver depression forming fire type reflux esophagitis | |
| CN103110895B (en) | Preparation method of traditional Chinese medicine for treating strong tea drinking type reflux oesophagitis | |
| CN103110913B (en) | Preparation method of traditional Chinese medicine for treating qi-deficiency type reflux oesophagitis | |
| CN102366545B (en) | Preparation method for traditional Chinese medicine used for treating subconjunctival blood stasis type gastritis | |
| CN103110842B (en) | Preparation method of traditional Chinese medicine for treating vomit type reflux oesophagitis | |
| CN103110900B (en) | Preparation method of traditional Chinese medicine for treating liver depression type reflux esophagitis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| ASS | Succession or assignment of patent right |
Owner name: BINZHOU MEDICAL UNIVERSITY HOSPITAL Free format text: FORMER OWNER: JI ZHONGHUA Effective date: 20140311 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| C53 | Correction of patent of invention or patent application | ||
| CB03 | Change of inventor or designer information |
Inventor after: Gao Tao Inventor after: Wang Xia Inventor after: Mou Weiping Inventor after: Wang Jian Inventor after: Wang Xiuhua Inventor after: Liu Jing Inventor before: Ji Zhonghua |
|
| COR | Change of bibliographic data |
Free format text: CORRECT: ADDRESS; FROM: 250200 JINAN, SHANDONG PROVINCE TO: 256603 BINZHOU, SHANDONG PROVINCE Free format text: CORRECT: INVENTOR; FROM: JI ZHONGHUA TO: GAO TAO WANG XIA MOU WEIPING WANG JIAN WANG XIUHUA LIU JING |
|
| TA01 | Transfer of patent application right |
Effective date of registration: 20140311 Address after: 256603 the Yellow River Road, Shandong, No. two, No. 661, Binzhou Applicant after: Binzhou Medical University Hospital Address before: 250200 Zhangqiu people's Hospital, Ji'nan, Shandong Applicant before: Ji Zhonghua |
|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20140409 Termination date: 20150215 |
|
| EXPY | Termination of patent right or utility model |