CN103083640B - Medicament for treating vomiting caused by chemotherapy - Google Patents
Medicament for treating vomiting caused by chemotherapy Download PDFInfo
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- CN103083640B CN103083640B CN201310030119.9A CN201310030119A CN103083640B CN 103083640 B CN103083640 B CN 103083640B CN 201310030119 A CN201310030119 A CN 201310030119A CN 103083640 B CN103083640 B CN 103083640B
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Abstract
The invention relates to a medicament for treating vomiting caused by chemotherapy. The medicament is prepared from the following bulk pharmaceutical chemicals: veratrum nigrum, salvia miltiorrhiza, ligusticum wallichii, astragalus mongholicus, radix saposhnikoviae, rhizoma zingiberis, phyllanthus emblica, rice sprout, potentilla chinensis, herba artemisiae capillaris and radix tinosporae. The medicament for treating vomiting caused by chemotherapy uses natural medicines, so that the medicament has the advantages of quick effectiveness, good efficacy and no toxic and side effects.
Description
Technical field
The present invention relates to clinical tumor nursing field, specifically, relate to a kind of chemotherapy for the treatment of
The medicament of induced Vomiting reaction.
Background technology
Intravenous chemotherapy is one of important method of a few days ago treating malignant tumor, but common toxicity, particularly insufferable nausea and vomiting have brought the misery in treatment to patient, so that many patients are frightened or refusal chemotherapy.Especially, cisplatin is the common chemotherapeutics for the treatment of tumor, has been found that in the process of cisplatin chemotherapy, must be accompanied by this phenomenon of nausea and vomiting, to patient, has brought larger misery.At present, the medicine reacting in the urgent need to a kind of effective treatment Vomiting Induced by Chemotherapy.
Summary of the invention
The object of this invention is to provide a kind of medicament for the treatment of Vomiting Induced by Chemotherapy reaction.
In order to realize object of the present invention, the invention provides a kind of medicament for the treatment of Vomiting Induced by Chemotherapy reaction, it is to be made by weight by following bulk drugs: Rhizoma et radix veratri (Radix Rhizoma Veratri) 5-10 part, Radix Salviae Miltiorrhizae 10-20 part, Rhizoma Chuanxiong 20-30 part, Radix Astragali 10-20 part, Radix Saposhnikoviae 10-20 part, Rhizoma Zingiberis 5-15 part, Fructus Phyllanthi 10-30 part, Fructus Setariae Germinatus 10-20 part, Herba Potentillae Chinensis 5-10 part, Herba Artemisiae Scopariae 10-20 and Radix Tinosporae 5-10 part.
Preferably, it is to be made by weight by following bulk drugs: 8 parts of 8 parts of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 15 parts of Radix Salviae Miltiorrhizaes, 25 parts of Rhizoma Chuanxiongs, 15 parts of the Radixs Astragali, 15 parts of Radix Saposhnikoviaes, 10 parts of Rhizoma Zingiberiss, 20 parts of Fructus Phyllanthis, 15 parts of Fructus Setariae Germinatuss, 8 parts of Herba Potentillae Chinensis, Herba Artemisiae Scopariae 15 and Radix Tinosporaes.
Preferably, described pharmaceutical composition is made tablet, dispersible tablet, buccal tablet, powder or granule.
The medicament for the treatment of Vomiting Induced by Chemotherapy reaction of the present invention is used natural drug, so it has advantages of instant effect, good effect, has no side effect.
The specific embodiment
Below the invention will be further described for the description by the specific embodiment, but this is not limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise depart from basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment 1 powder of the present invention
Get 80 grams of 80 grams of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 150 grams of Radix Salviae Miltiorrhizaes, 250 grams of Rhizoma Chuanxiongs, 150 grams of the Radixs Astragali, 150 grams of Radix Saposhnikoviaes, 100 grams of Rhizoma Zingiberiss, 200 grams of Fructus Phyllanthis, 150 grams of Fructus Setariae Germinatuss, 80 grams of Herba Potentillae Chinensis, 150 grams of Herba Artemisiae Scopariaes and Radix Tinosporaes, pulverize, cross 100 mesh sieves, then add 300 grams of sucrose, mix, pack in 100 bags and get final product.
Experimental example
Observe altogether treatment 60 examples and all through pathology, be diagnosed as the patients undergoing chemotherapies of malignant tumor, male 42 examples wherein, female's 18 examples, age 29-68 year, average 45.8 years old; Wherein adenocarcinoma of lung 16 examples, lung squamous cancer 12 examples, bronchovesicular cancer 1 example, small cell lung cancer 3 examples, esophageal carcinoma 16 examples, nasopharyngeal carcinoma 8 examples, Epithelial ovarian tumor 3 examples, ovarian germ cell tumors 1 example.
Inclusive criteria
MethodsThe cases enrolled all meets following condition: diagnosis clearly needs row combined chemotherapy; In the obstinate vomit 24h causing without intracranial hypertension, intestinal obstruction or other reason all without vomiting and do not use Bendectin person; Check that electrocardiogram, routine blood test, liver function, kidney merit, blood sugar effects are all normal before chemotherapy; Can cooperation observe nausea and vomiting responder, all complete 2 cycle chemotherapy, can Estimating curative effect and untoward reaction; All with cisplatin, treat cisplatin consumption >=30mg/ day.
With the powder making in embodiment 1, treat, wherein one day 3 times, each oral one bag.Observe the chemotherapy vomiting of 1-5 days and control situation.
Criterion of therapeutical effect
Alleviate completely: without vomiting; Partial rcsponse: vomiting 1-2 times/day; Slight alleviation: vomiting 3-5 times/day; Invalid: to vomit >=6 times/day.
Find that 60 routine patients all do not produce the phenomenon of any nausea and vomiting in chemotherapy in 1-5 days, and during whole treatment, do not observe significantly other untoward reaction.
Claims (1)
1. treat the medicament that Vomiting Induced by Chemotherapy reacts for one kind, it is characterized in that, it is to be made by following bulk drugs: 80 grams of 80 grams of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 150 grams of Radix Salviae Miltiorrhizaes, 250 grams of Rhizoma Chuanxiongs, 150 grams of the Radixs Astragali, 150 grams of Radix Saposhnikoviaes, 100 grams of Rhizoma Zingiberiss, 200 grams of Fructus Phyllanthis, 150 grams of Fructus Setariae Germinatuss, 80 grams of Herba Potentillae Chinensis, 150 grams of Herba Artemisiae Scopariaes and Radix Tinosporaes.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310030119.9A CN103083640B (en) | 2013-01-28 | 2013-01-28 | Medicament for treating vomiting caused by chemotherapy |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310030119.9A CN103083640B (en) | 2013-01-28 | 2013-01-28 | Medicament for treating vomiting caused by chemotherapy |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103083640A CN103083640A (en) | 2013-05-08 |
| CN103083640B true CN103083640B (en) | 2014-02-05 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN201310030119.9A Expired - Fee Related CN103083640B (en) | 2013-01-28 | 2013-01-28 | Medicament for treating vomiting caused by chemotherapy |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101152433A (en) * | 2007-09-15 | 2008-04-02 | 尹克华 | Traditional Chinese medicine for treating chemotherapy leukocytopenia after mammary cancer operation |
-
2013
- 2013-01-28 CN CN201310030119.9A patent/CN103083640B/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101152433A (en) * | 2007-09-15 | 2008-04-02 | 尹克华 | Traditional Chinese medicine for treating chemotherapy leukocytopenia after mammary cancer operation |
Non-Patent Citations (6)
| Title |
|---|
| 卢伟.癌症患者化疗期间癌因性疲乏中医临床辨治探讨.《吉林中医药》.2010,第30卷(第12期),1054-1055. |
| 李海峰.藏药六味木香丸治疗肿瘤化疗后恶心呕吐72例观察.《中国民族医药杂志》.2007,(第9期),13. |
| 林洪生中医药配合放化疗治疗肿瘤经验初探;石玉春;《北京中医药》;20120331;第31卷(第3期);182-184 * |
| 癌症患者化疗期间癌因性疲乏中医临床辨治探讨;卢伟;《吉林中医药》;20101231;第30卷(第12期);1054-1055 * |
| 石玉春.林洪生中医药配合放化疗治疗肿瘤经验初探.《北京中医药》.2012,第31卷(第3期),182-184. |
| 藏药六味木香丸治疗肿瘤化疗后恶心呕吐72例观察;李海峰;《中国民族医药杂志》;20070831(第9期);13 * |
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