CN103083640A - Medicament for treating vomiting caused by chemotherapy - Google Patents

Medicament for treating vomiting caused by chemotherapy Download PDF

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Publication number
CN103083640A
CN103083640A CN2013100301199A CN201310030119A CN103083640A CN 103083640 A CN103083640 A CN 103083640A CN 2013100301199 A CN2013100301199 A CN 2013100301199A CN 201310030119 A CN201310030119 A CN 201310030119A CN 103083640 A CN103083640 A CN 103083640A
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China
Prior art keywords
radix
parts
medicament
rhizoma
chemotherapy
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CN2013100301199A
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Chinese (zh)
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CN103083640B (en
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吴雪梅
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Individual
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Abstract

The invention relates to a medicament for treating vomiting caused by chemotherapy. The medicament is prepared from the following bulk pharmaceutical chemicals: veratrum nigrum, salvia miltiorrhiza, ligusticum wallichii, astragalus mongholicus, radix saposhnikoviae, rhizoma zingiberis, phyllanthus emblica, rice sprout, potentilla chinensis, herba artemisiae capillaris and radix tinosporae. The medicament for treating vomiting caused by chemotherapy uses natural medicines, so that the medicament has the advantages of quick effectiveness, good efficacy and no toxic and side effects.

Description

A kind of medicament for the treatment of the Vomiting Induced by Chemotherapy reaction
Technical field
The present invention relates to the clinical tumor nursing field, specifically, relate to a kind of chemotherapy for the treatment of
The medicament of induced Vomiting reaction.
Background technology
Intravenous chemotherapy is one of important method of a few days ago treating malignant tumor, but common toxicity, particularly insufferable nausea and vomiting have brought the misery in the treatment to the patient, so that many patients are frightened or the refusal chemotherapy.Especially, cisplatin is the common chemotherapeutics for the treatment of tumor, has been found that in the process of cisplatin chemotherapy, must be accompanied by this phenomenon of nausea and vomiting, has brought larger misery to the patient.At present, the medicine that reacts in the urgent need to a kind of effective treatment Vomiting Induced by Chemotherapy.
Summary of the invention
The purpose of this invention is to provide a kind of medicament for the treatment of the Vomiting Induced by Chemotherapy reaction.
In order to realize purpose of the present invention, the invention provides a kind of medicament for the treatment of the Vomiting Induced by Chemotherapy reaction, it is to be made by weight by following bulk drugs: Rhizoma et radix veratri (Radix Rhizoma Veratri) 5-10 part, Radix Salviae Miltiorrhizae 10-20 part, Rhizoma Chuanxiong 20-30 part, Radix Astragali 10-20 part, Radix Saposhnikoviae 10-20 part, Rhizoma Zingiberis 5-15 part, Fructus Phyllanthi 10-30 part, Fructus Setariae Germinatus 10-20 part, Herba Potentillae Chinensis 5-10 part, Herba Artemisiae Scopariae 10-20 and Radix Tinosporae 5-10 part.
Preferably, it is to be made by weight by following bulk drugs: 8 parts of 8 parts of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 15 parts of Radix Salviae Miltiorrhizaes, 25 parts of Rhizoma Chuanxiongs, 15 parts of the Radixs Astragali, 15 parts of Radix Saposhnikoviaes, 10 parts of Rhizoma Zingiberiss, 20 parts of Fructus Phyllanthis, 15 parts of Fructus Setariae Germinatuss, 8 parts of Herba Potentillae Chinensis, Herba Artemisiae Scopariae 15 and Radix Tinosporaes.
Preferably, described pharmaceutical composition is made tablet, dispersible tablet, buccal tablet, powder or granule.
The medicament for the treatment of Vomiting Induced by Chemotherapy reaction of the present invention uses natural drug, so it has advantages of instant effect, good effect, has no side effect.
The specific embodiment
Below the invention will be further described for the description by the specific embodiment, but this is not to be limitation of the present invention, those skilled in the art are according to basic thought of the present invention, can make various modifications or improvement, but only otherwise break away from basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment 1 powder of the present invention
Get Rhizoma et radix veratri (Radix Rhizoma Veratri) 80 grams, Radix Salviae Miltiorrhizae 150 grams, Rhizoma Chuanxiong 250 grams, the Radix Astragali 150 grams, Radix Saposhnikoviae 150 grams, Rhizoma Zingiberis 100 grams, Fructus Phyllanthi 200 grams, Fructus Setariae Germinatus 150 grams, Herba Potentillae Chinensis 80 grams, Herba Artemisiae Scopariae 150 grams and Radix Tinosporae 80 grams, pulverize, cross 100 mesh sieves, then add sucrose 300 grams, mixing is packed in 100 bags and get final product.
Experimental example
Observe altogether treatment 60 examples and all be diagnosed as the patients undergoing chemotherapies of malignant tumor through pathology, male 42 examples wherein, female's 18 examples, age 29-68 year, average 45.8 years old; Wherein adenocarcinoma of lung 16 examples, lung squamous cancer 12 examples, bronchovesicular cancer 1 example, small cell lung cancer 3 examples, esophageal carcinoma 16 examples, nasopharyngeal carcinoma 8 examples, Epithelial ovarian tumor 3 examples, ovarian germ cell tumors 1 example.
Inclusive criteria
MethodsThe cases enrolled all meets following condition: diagnosis clearly need be gone combined chemotherapy; In the obstinate vomit 24h that causes without intracranial hypertension, intestinal obstruction or other reason all without vomiting and do not use the Bendectin person; Check that electrocardiogram, routine blood test, liver function, kidney merit, blood sugar effects are all normal before chemotherapy; Can cooperation observe the nausea and vomiting responder, all complete 2 cycle chemotherapy, but Estimating curative effect and untoward reaction; All treat cisplatin consumption 〉=30mg/ day with cisplatin.
Treat with the powder that makes in embodiment 1, wherein one day 3 times, each oral one bag.Observe the chemotherapy vomiting of 1-5 days and control situation.
Criterion of therapeutical effect
Alleviate fully: without vomiting; Partial rcsponse: vomit 1-2 times/day; The slight alleviation: vomit 3-5 times/day; Invalid: as to vomit 〉=6 times/days.
Find that 60 routine patients all do not produce the phenomenon of any nausea and vomiting in chemotherapy in 1-5 days, and do not observe significantly other untoward reaction during whole treatment.

Claims (3)

1. treat the medicament that Vomiting Induced by Chemotherapy reacts for one kind, it is characterized in that, it is to be made by weight by following bulk drugs: Rhizoma et radix veratri (Radix Rhizoma Veratri) 5-10 part, Radix Salviae Miltiorrhizae 10-20 part, Rhizoma Chuanxiong 20-30 part, Radix Astragali 10-20 part, Radix Saposhnikoviae 10-20 part, Rhizoma Zingiberis 5-15 part, Fructus Phyllanthi 10-30 part, Fructus Setariae Germinatus 10-20 part, Herba Potentillae Chinensis 5-10 part, Herba Artemisiae Scopariae 10-20 and Radix Tinosporae 5-10 part.
2. the medicament for the treatment of Vomiting Induced by Chemotherapy according to claim 1 reaction, it is characterized in that, it is to be made by weight by following bulk drugs: 8 parts of 8 parts of Rhizoma et radix veratri (Radix Rhizoma Veratri)s, 15 parts of Radix Salviae Miltiorrhizaes, 25 parts of Rhizoma Chuanxiongs, 15 parts of the Radixs Astragali, 15 parts of Radix Saposhnikoviaes, 10 parts of Rhizoma Zingiberiss, 20 parts of Fructus Phyllanthis, 15 parts of Fructus Setariae Germinatuss, 8 parts of Herba Potentillae Chinensis, Herba Artemisiae Scopariae 15 and Radix Tinosporaes.
3. the medicament for the treatment of Vomiting Induced by Chemotherapy reaction according to claim 1 and 2, is characterized in that, described medicament can be tablet, dispersible tablet, buccal tablet, powder or granule.
CN201310030119.9A 2013-01-28 2013-01-28 Medicament for treating vomiting caused by chemotherapy Expired - Fee Related CN103083640B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201310030119.9A CN103083640B (en) 2013-01-28 2013-01-28 Medicament for treating vomiting caused by chemotherapy

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Application Number Priority Date Filing Date Title
CN201310030119.9A CN103083640B (en) 2013-01-28 2013-01-28 Medicament for treating vomiting caused by chemotherapy

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CN103083640A true CN103083640A (en) 2013-05-08
CN103083640B CN103083640B (en) 2014-02-05

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101152433A (en) * 2007-09-15 2008-04-02 尹克华 Traditional Chinese medicine for treating chemotherapy leukocytopenia after mammary cancer operation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101152433A (en) * 2007-09-15 2008-04-02 尹克华 Traditional Chinese medicine for treating chemotherapy leukocytopenia after mammary cancer operation

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
卢伟: "癌症患者化疗期间癌因性疲乏中医临床辨治探讨", 《吉林中医药》 *
李海峰: "藏药六味木香丸治疗肿瘤化疗后恶心呕吐72例观察", 《中国民族医药杂志》 *
石玉春: "林洪生中医药配合放化疗治疗肿瘤经验初探", 《北京中医药》 *

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