CN103081943A - Bactericidal composition containing simeconazole and JS399-19 - Google Patents
Bactericidal composition containing simeconazole and JS399-19 Download PDFInfo
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Abstract
The invention relates to a bactericidal composition containing simeconazole and JS399-19. The effective component of the bactericidal composition is compounded from simeconazole and JS399-19 in a mass ratio of (1-80):(80-1). The preparation is composed of 1-80 wt% of effective ingredient (simeconazole and JS399-19) and the balance of allowable and acceptable auxiliary components in pesticide. The bactericidal composition provided by the invention can be prepared into the pesticide formulations: missible oil, suspending agent, wettable powder, water-dispersible gradules, aqueous emulsion and microemulsion. The bactericidal composition is used for preventing and treating scab of wheat, wilt of cotton, Panama disease of banana, bakanae disease of rice and fusarium wilt of watermelon, and also has excellent preventing effect on powdery mildew, banana freckle, rust disease, seedling blight, banded sclerotial blight and the like.
Description
Technical field
The present invention relates to the agriculture chemical compounding technical field, be specifically related to a kind of bactericidal composition that contains simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate.
Background technology
The common companies of simeconazoles system Japan three (are now three common A, company) in siliceous three series bactericidal agents of exploitation in 1991, it is the deep and remote pure biosynthesis inhibitor of a kind of ergot, destroy and stop the biosynthesis of the cell membrane important composition composition ergosterol of germ, cause cell membrane not form, make germ dead.Due to absorption in having well, therefore can be promptly by plant absorbing, and in conducted inside; Have good protection and therapeutic activity.Can effectively prevent and treat disease due to numerous sac fungis, basidiomycetes and imperfect fungus, especially all kinds of powdery mildews, scab, rust, damping off, banded sclerotial blight etc. be had excellent preventive effect.The chemistry of simeconazoles is called (R, S)-2-(4 fluorophenyl)-1-(1H-1,2,4-triazol-1-yl)-3-trimethyl silicane propane-2-alcohol, and its chemical structural formula is
2-cyano-3-amino-3-phenylancryic acetate is the cyanoacrylate bactericide of a kind of novel structure, mode of action uniqueness, chemical name: 2-cyano group-3-aminoacrylic acid ethyl ester, 2-cyano-3-amino-3-phenylancryic acetate is effective to the disease that the reaping hook mushroom causes, has protective effect and therapeutic action.Can be used for preventing and treating wheat scab, cotton wilt, banana Panama disease, bakanae disease of rice, watermelon blight etc.
Using chemical agent is the most effectively means of controlling plant diseases.But long-term use single chemical bactericide continuously high dose, easily cause the problems such as residual, the environmental pollution of medicament and anti-pesticide resistance fungi development.Reasonably chemical bactericide is composite or be mixed and have the expansion fungicidal spectrum, improve control efficiency, extend the optimum period for applying fertilizer, reduce dosage, reduce poisoning, reduce residual, delay Antifungal resistance and the positive characteristics such as drug-fast generation and development, bactericide compounded is one of the effective method the most that addresses the above problem.Exploitation new product bactericide price is constantly soaring, and by contrast, exploitation is efficient with research, low toxicity, low-residual composite be mixed have small investment, the lead time is short and be subject to domestic and international attention, the numerous and confused dynamics that develops that strengthens.We filter out simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate and carry out compositely on the basis of lab screening and field trial, have obvious synergistic effect.And about the composite bactericidal composition of simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate and use and there is no at present the people and reported.
Summary of the invention
Based on above situation, the object of the invention is to provide a kind of new and effective pesticide sterilizing composite.Be used for preventing and treating wheat scab, cotton wilt, banana Panama disease, bakanae disease of rice, watermelon blight, all kinds of powdery mildews, scab, rust, damping off, banded sclerotial blight etc. are also had excellent preventive effect.
Technical scheme of the present invention realizes by following measures:
A kind of bactericidal composition that contains simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate, two yuan of the active ingredient simeconazoles of this bactericidal composition and 2-cyano-3-amino-3-phenylancryic acetates are composite, and all the other are auxiliary element.In wherein said Pesticidal combination, the mass ratio of active ingredient simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate is 1～80: 80～1, described bactericidal composition of the present invention is through the toxicity test experimental verification, the mass ratio of simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate is 1～40: 50～1 o'clock, and synergistic effect is better.
The formulations of pesticide that described bactericidal composition of the present invention can be prepared are missible oil, suspending agent, wetting powder, water dispersible granules, aqueous emulsion, microemulsion.Wherein active ingredient simeconazoles and the 2-cyano-3-amino-3-phenylancryic acetate gross mass in preparation accounts for 1%～80% of the whole quality of the pharmaceutical preparations, when wherein accounting for 5%-55%, and toxicity and the residual balance preferably that reaches, cost is also lower.
The specific embodiments of the formulations of pesticide that bactericidal composition of the present invention is mixed with is as follows:
Described bactericidal composition is cream preparation, and the mass fraction of component is: simeconazoles 1～80; 1～80 part of 2-cyano-3-amino-3-phenylancryic acetate; 10～30 parts of conventional emulsifiers; 20～50 parts of conventional solvents; 1～5 part of conventional synergist.The concrete production stage of this cream preparation adds emulsifier, the synergist rear oily liquids that becomes transparent and homogeneous that stirs after dissolving fully in solvent again for first active ingredient simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate being added, can namely can be made into the cream preparation of the present composition.
Described bactericidal composition is suspending agent, and the mass fraction of component is: 1～80 part of simeconazoles; 1～80 part of 2-cyano-3-amino-3-phenylancryic acetate; 5～20 parts of dispersants; 1～5 part of antifreezing agent; 0.1～2 part of thickener; 0.1～0.8 part of defoamer; 0～10 part of penetrating agent; 0.1～5 part of pH value conditioning agent; Water, surplus.The concrete production stage of this suspending agent is for first mixing other auxiliary agents, mix through high speed shear, add active ingredient simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate, abrading-ball is 2～3 hours in ball crusher, make a diameter all below 5mm, namely can be made into the suspending agent preparation of the present composition.
Described bactericidal composition is wetting powder, and the mass fraction of component is: 1～80 part of simeconazoles; 1～80 part of 2-cyano-3-amino-3-phenylancryic acetate; 3～10 parts of dispersants; 1～5 part of wetting agent; Filler, surplus.The concrete production stage of this wetting powder is: by above-mentioned formula, the active ingredient simeconazoles is mixed with 2-cyano-3-amino-3-phenylancryic acetate and dispersant, wetting agent and filler, uniform stirring in stirred tank, mixing after airslide disintegrating mill, namely can be made into the wetting powder of the present composition.
Described bactericidal composition is water dispersible granules, and the mass fraction of component is: 1～80 part of simeconazoles; 1～80 part of 2-cyano-3-amino-3-phenylancryic acetate; 3～10 parts of dispersants; 1～10 part of wetting agent; 1～5 part of disintegrant; The filler surplus.The concrete production stage of this water dispersible granules is: by above-mentioned formula, active ingredient simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate and dispersant, wetting agent, disintegrant and filler are mixed, pulverize with micro jet, through mediating, then add and carry out granulation, drying, screening in the fluidized bed prilling dryer by sample analysis, namely can be made into the water dispersible granules of the present composition.
Described bactericidal composition is aqueous emulsion, and the mass fraction of component is: 1～80 part of simeconazoles; 1～80 part of 2-cyano-3-amino-3-phenylancryic acetate; 3～30 parts of emulsifier; 5～15 parts of solvents; 2～15 parts of stabilizing agents; 1～5 part of antifreezing agent; 0.1～8 part of defoamer; 0.2～2 part of thickener; Water surplus.The concrete production stage of this aqueous emulsion is: at first simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate, solvent and emulsifier, cosolvent are added together, make to be dissolved into uniform oil phase; With part water, antifreeze, other the insecticides adjuvant such as antimicrobial mixes into uniform water; When the reactor high speed stirs, oil phase is added water, slowly add water until reach the phase inversion point, open clipper and carry out high speed shear, and add remaining water, shear about half an hour, form the aqueous emulsion of oil-in-water type, namely can be made into the aqueous emulsion of the present composition.
Described bactericidal composition is microemulsion, and the mass fraction of component is: 1～80 part of simeconazoles, 1～80 part of simeconazoles, 10～30 parts of emulsifier, 1～8 part of antifreezing agent, 0.5～10 part of stabilizing agent, 20～50 parts of conventional solvent cosolvents.Simeconazoles and simeconazoles are dissolved fully with cosolvent, then add other compositions such as emulsifier, antifreezing agent stabilizing agent, evenly mix, add at last entry, can be made into microemulsion after fully stirring.
Wherein above-described emulsifier is selected from calcium dodecyl benzene sulfonate and aliphatic acid polyethenoxy ether, the alkylphenol polyoxyethylene sulfosuccinate, styrylphenol polyoxyethylene ether, polyoxyethylene nonylphenol ether, castor oil polyoxyethylene ether, aliphatic acid polyethenoxy base ester, any or more than one any mixtures than forming in polyoxyethylene aliphatic alcohol ether.
Described solvent is dimethylbenzene or biodiesel, toluene, and diesel oil, methyl alcohol, ethanol, n-butanol, isopropyl alcohol, turpentine oil, solvent naphtha, dimethyl formamide, dimethyl sulfoxide (DMSO), one or more in the water equal solvent are arbitrarily than the mixture that forms.
Described dispersant is selected from polycarboxylate, lignosulfonates, alkylphenol polyoxyethylene methyl ether condensate sulfate, the alkylsulfonate calcium salt, the naphthalene sulfonic acid-formaldehyde condensation product sodium salt, alkylphenol polyoxyethylene, polyoxyethylene carboxylate, aliphatic amine polyoxyethylene ether, one or more in the fatty acid glyceride APEO.
Described wetting agent is selected from lauryl sodium sulfate, calcium dodecyl benzene sulfonate, and Nekal BX, moistening bleeding agent F, alkylbenzenesulfonate polyoxyethylene triphen is phosphenylic acid salt dimly, spaonin powder, silkworm excrement, one or more in the soapberry powder.
Described disintegrant is selected from bentonite, urea, ammonium sulfate, aluminium chloride, citric acid, succinic acid, one or more in sodium bicarbonate.
Described thickener is selected from xanthans, carboxymethyl cellulose, carboxyethyl cellulose, methylcellulose, Magnesiumaluminumsilicate, in polyvinyl alcohol one or more.
Described stabilizing agent is selected from sodium citrate, a kind of in resorcinol.
Described antifreezing agent is selected from ethylene glycol, propane diols, one or more in glycerine.
Described defoamer is selected from silicone oil, silicone compound, C
10-20The saturated fat acid compounds, C
8-10One or more of fatty alcohol.
Described filler is selected from kaolin, diatomite, bentonite, attapulgite, white carbon, starch, one or more in precipitated calcium carbonate.
The composite bactericide of the present invention take simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate as active ingredient has obvious synergistic effect, delays the drug-fast generation in key, and reduced to become to produce cost and use cost, can be used for the improvement of resistance disease.Be used for preventing and treating wheat scab, cotton wilt, banana Panama disease, bakanae disease of rice, watermelon blight, all kinds of powdery mildews, scab, rust, damping off, banded sclerotial blight etc. are also had excellent preventive effect.
Embodiment
For making technical scheme of the present invention, purpose and advantage are clearer, and the present invention describes with following specific embodiment, but the present invention is not limited to these examples.The mode that effect experiment of the present invention adopts indoor biometrics and field trial to combine, if no special instructions, the ratio of below mentioning is all ratio of quality and the number of copies.
Embodiment: simeconazoles proportioning co-toxicity experiments different from 2-cyano-3-amino-3-phenylancryic acetate.
1.1 reagent agent
The 95 former medicines of % simeconazoles, the 95% former medicine of 2-cyano-3-amino-3-phenylancryic acetate, above-mentioned former medicine provides by research and development department of extra large rel medicine company limited company.
1.2 test target
Never executed simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate and cucumber of the same type from Shouguang, Shandong and gather potted plantly and separate, for the examination cucumber variety: Chang Chun Mi Ci.
1.3 test method
1.3.1 medicament preparation
First use the former medicine of acetone solution, according to the result of preliminary experiment, two appropriate former medicines are made into 5 different proportionings, then with acetone, each is processed that to be diluted to respectively 5 concentration gradients stand-by, the ratio of 5 simeconazoles proportioning active ingredients different from 2-cyano-3-amino-3-phenylancryic acetate is respectively 5:46; 10:41; 15:36; 20:31; 25:26.
Susceptible cucumber variety Chang Chun Mi Ci cultivation in pot for growing seedlings, is placed in the greenhouse and cultivates, and plant grows to three to four leaf after dates, gathers the blade of identical leaf age, is used for cultivation and the mensuration of powdery mildew of cucumber bacterium.
1.3.2 the cultivation of powdery mildew of cucumber bacterium and the preparation of spore suspension
The powdery mildew of cucumber bacterium adopts the plants method to cultivate under 20 ℃, the condition of 12h alternation of light and darkness, and every 30 d turn culture 1 time.During inoculation, with the conidium on sterile water wash-out incidence of leaf, being mixed with spore concentration is l * 10
6The suspension of individual/mL.
1.3.3 strains tested sensitivity testing
Adopt leaf dish moisturizing method to carry out toxicity test.First the blade that gathers is prepared into the leaf dish that diameter is 1.5cm, random mixing, be placed in respectively the series concentration liquid that configures and soak lh, 50 leaf dishes of each concentration, test is with the blank that is treated to of adding medicine not, after soaking end, leaf faces up and puts on the wetting blotting paper of identical liquor strength, liquid on the leaf dish is blotted, the spore suspension l0L for preparing is inoculated in leaf dish central authorities, after room temperature is placed 5 min, is placed under 20 ℃, the condition of 1 2h alternation of light and darkness and cultivates, measure the onset area on the leaf dish after 10d, calculate EC
50
On the basis of preliminary experiment, respectively single dose simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate are carried out toxicity test, both EC in order to upper method
50Value is respectively 6.14 ㎎/l and 16.09 ㎎/l
The percentage that accounts for the leaf disc area according to lesion area is divided sick level
0 grade: anosis;
1 grade: the sorus area accounts for below 5% of whole leaf area;
3 grades: the sorus area accounts for below the 6%-10% of whole leaf area;
5 grades: the sorus area accounts for below the 11%-20% of whole leaf area;
7 grades: the sorus area accounts for below the 21%-50% of whole leaf area;
9 grades: the sorus area accounts for more than 50% of whole leaf area;
1.3.4 mixture toxicity test and interpretation of result
Carry out the toxicity test of mixture according to mixed ratio with single dose toxicity test method.
If contrast lethality＜5% is not proofreaied and correct, the contrast lethality by formula 2 is proofreaied and correct between 5%-20%, the contrast lethality〉20%, test need be reformed.
Take the logarithm value of drug concentration (mg/L) as independent variable x, take the probability value of corrected mortality as dependent variable y, set up respectively the virulence regression equation formula, adopt DPS software to calculate the LC of single dose and each proportioning mixture
50Calculate co-toxicity coefficient (CTC) according to the abundant method of Sun Yun.Co-toxicity coefficient CTC, computing formula is as follows: (take simeconazoles as the standard medicament, its toxicity index is 100):
The LC of the toxicity index of 2-cyano-3-amino-3-phenylancryic acetate (TI)=simeconazoles
50The LC of/2-cyano-3-amino-3-phenylancryic acetate
50* 100
The LC of the true toxicity index (ATI) of M=simeconazoles
50The LC of/M
50* 100
The TI of the TI of the theoretical toxicity index (TTI) of M=simeconazoles * P simeconazoles+2-cyano-3-amino-3-phenylancryic acetate * P 2-cyano-3-amino-3-phenylancryic acetate
The TTI of the ATI/M of the co-toxicity coefficient of M (CTC)=M * 100
In formula:
M is simeconazoles and the mixture of the different proportionings of 2-cyano-3-amino-3-phenylancryic acetate
The P simeconazoles is simeconazoles shared ratio in mixture
The P 2-cyano-3-amino-3-phenylancryic acetate is 2-cyano-3-amino-3-phenylancryic acetate shared ratio in mixture
2.1 toxicity test result
Table 1 simeconazoles and the 2-cyano-3-amino-3-phenylancryic acetate toxicity test to powdery mildew of cucumber
| Process title | Proportioning | Virulence regression equation (Y=a+bX) | The correlation coefficient r value | LC 50（mg/L） | Co-toxicity coefficient (CTC) |
| Simeconazoles | _____ | Y=2.5694X+2.9749 | 0.9894 | 6.14 | _______ |
| 2-cyano-3-amino-3-phenylancryic acetate | _____ | Y=2.6964X+1.7466 | 0.9882 | 16.09 | _______ |
| Simeconazoles: 2-cyano-3-amino-3-phenylancryic acetate | 30：24 | Y=2.7374X+2.3656 | 0.9892 | 9.17 | 151.39 |
| Simeconazoles: 2-cyano-3-amino-3-phenylancryic acetate | 33：21 | Y=2.4694X+2.8363 | 0.9914 | 7.52 | 162.45 |
| Simeconazoles: 2-cyano-3-amino-3-phenylancryic acetate | 36：18 | Y=2.7432X+2.8263 | 0.9891 | 6.20 | 175.86 |
| Simeconazoles: 2-cyano-3-amino-3-phenylancryic acetate | 39：15 | Y=2.7963X+2.7725 | 0.9884 | 6.26 | 157.11 |
| Simeconazoles: 2-cyano-3-amino-3-phenylancryic acetate | 42：12 | Y=2.9423X+2.6893 | 0.9901 | 6.10 | 146.92 |
As can be seen from the table, the result of the test of different proportion proportioning shows, is 5:46 in the active ingredient ratio; 10:41; 15:36; 20:31; When 25:26 dilutes respectively, all show stronger synergistic effect, wherein take simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate as 15:36 the time synergistic effect best, its co-toxicity coefficient is 170.82.Suggestion is carried out further field control effectiveness test to suitable proportion 15:36 left and right mixture preparation, to estimate its field practical application effect.
3, the experimental result of field trial control wheat powdery mildew, head blight
3.1 field trial control wheat powdery mildew
3.1.1 basic condition experimental field
Experimental field be located at Henan, select the medium wheat paddock of occurring degree for experimental field, soil fertility is medium, and irrigation and drainage are convenient.Dispenser weather in April on the same day 1 is clear to cloudy, 11 ℃ of mean temperature of air, relative moisture 81%, 2～3 grades of southerlies; April 11 was fine day, 18.2 ℃ of mean temperature of air, relative moisture 60%, 2～3 grades of southerlies.
3.1.2 spraying time and method
At the 1st medicine of wheat powdery mildew their early stage (April 1) spray, after 10d (April 11) spray medicine for the second time, spray altogether 2 times.(operating pressure 0.2～0.3MPa), 750L carries out foliar spray according to the per hectare amount of liquid medicine to adopt the 3WBS-16 knapsack sprayer.
3.1.3 pilot survey and data are processed
Investigation state of an illness radix before medicine, test is investigated 3 times altogether, i.e. disease index investigation before medicine, preventive effect investigation in 10 days after the 1st medicine, 10 days and preventive effect investigation in 20 days after 2 medicines.
3.1.4 drug effect computational methods
Sick leaf rate (%)=sick number of sheets/investigate total number of sheets * 100
Disease index=∑ (the sick numbers of sheets at different levels * relative level numerical value)/(investigating total number of sheets * 9) * 100
Control efficiency (%)=(disease index after disease index before 1-(blank district medicine * treatment region medicine)/(after blank district medicine before disease index * treatment region medicine disease index)) * 100
3.1.5 poisoning investigation method
After dispenser, whether continuous 7d range estimation medicament has poisoning to crop.
3.1.6 experimental result and analysis
Table 2 is respectively organized the test effect that test medicine is processed the control wheat powdery mildew
Interpretation of result:
As shown in Table 2,51% simeconazoles 2-cyano-3-amino-3-phenylancryic acetate is more remarkable with the effect of 15:36 proportioning control wheat powdery mildew, after medicine 10 days for the first time, 10 days and 20 days preventive effects 91.35% the highest, 93.02% and 90.65% after medicine for the second time, and the effect of complex preparation significantly is better than two kinds of single doses, not only significantly improve the effect for wheat powdery mildew, and further extended its lasting period.
4.1 field trial is prevented and treated wheat scab
4.1.1 test method
Test is adopted the diagonal sampling at Shandong Pingdu City wheat paddock, 5 points of every residential quarter investigation, and the sick spike number in 100 1 200 wheat heads of every some casual inspection, severity extent is divided into 5 grades with ocular estimate:
0 grade anosis;
The sick spikelet number of I level accounts for below 1/4 of whole small ears;
The sick spikelet number of II level accounts for 1/4～1/2 of whole small ears;
The sick spikelet number of III level accounts for 1/2～3/4 of whole small ears;
The sick spikelet number of IV level accounts for more than 3/4 of whole small ears.
4.1.2 control time and number of times
Test is investigated 4 times altogether, radix investigation before medicine, for the first time after medicine 7 days, investigated in 15 days after 7 days and medicine after medicine for the second time.
4.1.3 drug effect computational methods
Disease tassel yield (%)=sick spike number/investigate total spike number * 100
Disease index=∑ (sick spike numbers at different levels * relative level numerical value)/(investigating total spike number * 4) * 100
Control efficiency (%)=(disease index after disease index before 1-(blank district medicine * treatment region medicine)/(after blank district medicine before disease index * treatment region medicine disease index)) * 100
4.1.4 poisoning investigation method
After dispenser, whether continuous 7d range estimation medicament has poisoning to crop.
4.1.5 result of the test and analysis
Each processes the effect (table 3) of preventing and treating wheat scab
Each processes the effect of preventing and treating wheat scab table 3
The Mixed Pharmacy of different proportion, test by different consumptions as can be seen from Table 3, and after medicine, its control to wheat scab all is better than contrasting medicament and bactericidal effect and increases progressively with the increase of dosage.After medicine, the preventive effect of 15 days is the highest for the second time still can reach 90.77, and according to the field range estimation, in the test dose scope, plant growth is normal, and the poisoning phenomenon to wheat does not all appear in each treatment agent, illustrates that it is safe to wheat.Advise that the bactericide different from the mechanism of action mixes use to delay the drug-fast generation of germ.
In sum, the present invention is the bactericidal composition that contains simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate, powdery mildew of cucumber, wheat powdery mildew, head blight etc. all had effect preferably, and it is to the target crop safety, compare with single dose, bactericidal composition of the present invention has advantages of that quick-acting is good, the lasting period is long, is difficult for producing poisoning, so research and development of the present invention and popularization are of great significance social tool.
Claims (5)
1. bactericidal composition that contains simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate, it is characterized in that: the active ingredient of this bactericidal composition is that simeconazoles and two yuan of 2-cyano-3-amino-3-phenylancryic acetates are composite, and wherein the mass ratio of active ingredient azoles bacterium ester and 2-cyano-3-amino-3-phenylancryic acetate is 1～80: 80～1.
2. bactericidal composition according to claim 1, it is characterized in that: the quality optimization ratio of simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate is 1～40: 50～1.
3. bactericidal composition according to claim 1, it is characterized in that: simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate account for 1%～80% of the whole quality of the pharmaceutical preparations.
4. bactericidal composition according to claim 3, it is characterized in that: simeconazoles and 2-cyano-3-amino-3-phenylancryic acetate account for 5%～55% of the whole quality of the pharmaceutical preparations.
5. according to claim 1 and 2 or 3 or 4 described bactericidal compositions, it is characterized in that: the formulations of pesticide that this bactericidal composition can be prepared into are missible oil, suspending agent, wetting powder, water dispersible granules, aqueous emulsion, microemulsion.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101584324A (en) * | 2009-04-15 | 2009-11-25 | 陕西蒲城县美邦农药有限责任公司 | 2-cyano-3-amino-3-phenylancryic acetate and epoxiconazole-containing antiseptic composition |
| CN101595890A (en) * | 2009-05-07 | 2009-12-09 | 深圳诺普信农化股份有限公司 | A kind of 2-cyano-3-amino-3-phenylancryic acetate and triazole type composition and application thereof |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101584324A (en) * | 2009-04-15 | 2009-11-25 | 陕西蒲城县美邦农药有限责任公司 | 2-cyano-3-amino-3-phenylancryic acetate and epoxiconazole-containing antiseptic composition |
| CN101595890A (en) * | 2009-05-07 | 2009-12-09 | 深圳诺普信农化股份有限公司 | A kind of 2-cyano-3-amino-3-phenylancryic acetate and triazole type composition and application thereof |
Non-Patent Citations (1)
| Title |
|---|
| 程志明: "杀菌剂硅氟唑的开发沿革", 《世界农药》 * |
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Application publication date: 20130508 |