Summary of the invention
The purpose of this invention is to provide a kind of have good inhibition foot antibacterial, conk breeding, prevent and treat beriberi, remove abnormal flavour, the footbath with traditional Chinese medicines care product of clearly soothing the spirit.
The preparation method of the antibacterial foot bath liquid of clearly soothing the spirit of above-mentioned Chinese medicine is provided, and is another goal of the invention of the present invention.
The antibacterial foot bath liquid of clearly soothing the spirit of Chinese medicine of the present invention is that the component by following parts by weight is that raw material is mixed and makes:
Chinese medicine extraction liquid 40.0-70.0
Emulsifying solubilizing agent 5.0-10.0
Ethanol 10.0-15.0
Radix Ginseng extractive solution 1.0-5.0
Borneolum Syntheticum 0.5-1.0
Oleum menthae 2.0-3.0
Glycerol 2.0-5.0
Essence 1.0-2.0
Purified water 8.5-19.
Wherein, described Chinese medicine extraction liquid is that the Chinese medicine by following parts by weight is raw material:
Radix Sophorae Flavescentis 30-40 Radix Isatidis 20-30
Herba Taraxaci 15-25 Herba Artemisiae Annuae 10-20
Herba Violae 10-15 Flos Lonicerae 10-20
Cortex Phellodendri 10-20 Radix Scutellariae 10-15
Herba Menthae 15-20 Fructus Cnidii 10-20.
Extract the Chinese medicine extraction liquid of the d=1.5-1.8g/ml that obtains take water as extractant.
Described Radix Ginseng extractive solution is take the Chinese medicine Radix Ginseng as raw material, and extraction obtains the extracting solution of content of ginsenoside 10-15wt% take water as extractant.
Further, emulsifying solubilizing agent of the present invention is one or more the mixture in tween 80, Arlacel-80, castor oil hydrogenated, the efficient solubilizing agents.
The concrete preparation method of the antibacterial foot bath liquid of clearly soothing the spirit of Chinese medicine of the present invention may further comprise the steps:
1), take by weighing raw material of Chinese medicine according to described parts by weight, decoct with water twice after the mixing, the 5-10 that each amount of water is Chinese medicine weight doubly decocted 1-1.5 hour, merged decoction liquor twice, was concentrated into d=1.5-1.8g/ml, and filtration obtains Chinese medicine extraction liquid;
2), emulsifying solubilizing agent, Radix Ginseng extractive solution, the glycerol with described parts by weight is dissolved in the Chinese medicine extraction liquid of described parts by weight abundant stirring and evenly mixing;
3), Oleum menthae, Borneolum Syntheticum, the essence with described parts by weight is dissolved in the ethanol of described parts by weight;
4), with above-mentioned 2) and 3) fully behind the emulsifying mixing, fill into the purified water of described parts by weight, fully stirring and evenly mixing is made the antibacterial foot bath liquid of clearly soothing the spirit of described Chinese medicine.
In the antibacterial foot bath liquid of clearly soothing the spirit of Chinese medicine of the present invention, mainly being extracted into of Radix Sophorae Flavescentis is divided into the alkaloids composition, and this composition all has obvious bacteriostasis to escherichia coli, staphylococcus aureus, dysentery bacterium and multiple pathogenic dermatophytes; Simultaneously have the effect of heat clearing and damp drying, parasite killing because of it, normal decocting liquid external is used for treatment and the prevention of scabies, leprosy, skin pruritus, noxious dampness skin infection.The effective ingredient of Cortex Phellodendri is mainly the flavones ingredients such as the alkaloids such as berberine and flavone Radix Hyperici Monogyni (Herba Hyperici Monogyni), except the multiple pathogenic dermatophytess such as the antibacterials such as staphylococcus aureus, streptococcus pneumoniae and acrothesium floccosum are had the stronger inhibitory action, the effect that also has simultaneously antiallergic action, in addition, Cortex Phellodendri has heat clearing and damp drying, and pathogenic fire purging is except steaming, and the effect of skin ulcer is treated in detoxifcation, but the decocting liquid washout is used for sore swollen toxin, treatment and the prevention of skin eczema pruritus etc.Radix Isatidis has the effects such as heat-clearing and toxic substances removing, removing heat from blood, and its infusion has inhibitory action to bacillus subtilis, staphylococcus aureus, sarcine, escherichia coli, Bacillus typhi, paratyphoid fever bacillus, dysentery (will Hayes, Fu Shi) bacillus, bacillus enteritidis etc.Flos Lonicerae is described as the good medicine of heat-clearing and toxic substances removing from ancient times, the property sweet cold fragrance, clearing away heat with drugs sweet in flavor and cold in nature and not injuring one's stomach, fragrance thoroughly reaches and can be eliminating evil, Flos Lonicerae can dispelling wind-heat, and also kind removing summer-heat blood poison is used for various febrile diseases, such as cards such as fever of the body, dermexanthesis, a speckle, pyretic toxicity carbuncle sore, laryngopharynx swelling and pain, all effect is remarkable.Fructus Cnidii is a herb commonly used in the TCM Dermatology external used medicine, finds that in treatment clinical course its antipruritic effect is good especially, is described as " pruritus of department of dermatologry ", the effect warming the kidney to invigorate YANG, removing dampness and killing parasites, dispelling wind for relieving itching cures mainly impotence in male, scrotum pruritus due to damp pathogen; Woman's infertility, cold-damp leukorrhagia, pudendal pruritus swell and ache, rheumatic arthralgia, eczema scabies.Herba Menthae is hot cold sweating antipyretic medicine, but external training the mind dysmenorrhoea, skin pruritus, erythra and eczema etc., in addition the Herba Menthae usefulness also often doing stagnation of QI due to depression of the liver, hypochondriac pain uncomfortable in chest, dispel the wind and calm the nerves.
Above medicinal herb components reasonable compatibility, the succinct Effective Component of Chinese Medicine that extracts is made the antibacterial foot bath liquid of clearly soothing the spirit of Chinese medicine, convert foot bath use in warm water, can be used in foot fungus, antibacterial and infect co-treatment and the prevention that causes beriberi, have simultaneously the good resolving depression that dispels the wind, clearly soothe the spirit, the effect of building body.
According to " disinfection technology standard " (version in 2002), under testing conditions separately, the antibacterial bacteriostasis property of clearly soothing the spirit foot bath liquid of Chinese medicine of the present invention is detected respectively, concrete testing result is as follows.
A, antibacterial 1: 100 the diluent of foot bath liquid of clearly soothing the spirit of Chinese medicine of the present invention are 1.89 * 10 to concentration
4The coli test of cfu/mL is with bacteria suspension effect 20min, each time bacteriostasis rate all>90%, product has stronger bacteriostasis for escherichia coli.
B, antibacterial 1: 100 the diluent of foot bath liquid of clearly soothing the spirit of Chinese medicine of the present invention are 2.62 * 10 to concentration
4The test of the staphylococcus aureus of cfu/mL is with bacteria suspension effect 20min, and each time bacteriostasis rate is equal>and 90%, product has stronger bacteriostasis for staphylococcus aureus.
C, antibacterial 1: 100 the diluent of foot bath liquid of clearly soothing the spirit of Chinese medicine of the present invention are 2.48 * 10 to concentration
4The test of the Candida albicans of cfu/mL is with bacteria suspension effect 20min, and each time bacteriostasis rate is equal>and 90%, product has stronger bacteriostasis for Candida albicans.
The antibacterial foot bath liquid of clearly soothing the spirit of D, Chinese medicine of the present invention is through 37 ℃ of insulations after 90 days, its diluent of 1: 100 is tested with bacteria suspension effect 20min staphylococcus aureus, escherichia coli, Candida albicans, each time bacteriostasis rate all>90%, with deposit front fungistatic effect without significant difference, show the fungistatic effect of escherichia coli, staphylococcus aureus, Candida albicans stable.
The antibacterial foot bath liquid of clearly soothing the spirit of Chinese medicine of the present invention select have good bactericidal, the natural plants of itch stopping and diminish inflammation, clearing away heat and cooling blood, the resolving depression effect of calming the nerves is raw material, product have good dissipation antibacterial, prevent and treat the beriberi effect, can promote the foot blood circulation simultaneously, dispel the wind and recover from fatigue, calm the nerves resolving depression, heat clearing away except dry, life-time service all has good effect for body-building health, raising immunity.Product of the present invention is easy to use, be in and add the enjoyment that an amount of hot water just can be enjoyed the Traditional Chinese medicine health-preserving foot bath, avoided infecting in defective public foot bath place the risk of beriberi even infectious disease, meet modern people pursue convenient fast, the rhythm of life of highly effective and safe.
The specific embodiment
Embodiment 1
Take by weighing Radix Sophorae Flavescentis 33kg, Radix Isatidis 22kg, Herba Taraxaci 17kg, Herba Artemisiae Annuae 12kg, Herba Violae 15kg, Flos Lonicerae 10kg, Cortex Phellodendri 15kg, Radix Scutellariae 10kg, Herba Menthae 10kg, Fructus Cnidii 15kg mix homogeneously, add water 1400L, decoct after 1 hour and filter, add again water 1000L in the medicinal residues, decoct after 1 hour and filter.Merge decoction liquor twice, be concentrated into d=1.8g/ml, filter and obtain Chinese medicine extraction liquid.
Take by weighing ethanol 150kg, stir lower Oleum menthae 20kg, essence 10kg, the Borneolum Syntheticum 10kg of dropping into, stirring is dissolved Borneolum Syntheticum fully and is obtained solution A.
Get Chinese medicine extraction liquid 480kg, stir lower tween 80 40kg, castor oil hydrogenated 60kg, Radix Ginseng extractive solution 50kg, the glycerol 50kg of slowly dropping into, fully stirring and evenly mixing obtains solution B.
Solution A and solution B are fully mixed, add purified water 130kg and stir.
Through after the assay was approved, the antibacterial foot bath liquid of clearly soothing the spirit of Chinese medicine is made in fill.
Embodiment 2
Take by weighing ethanol 100kg, stir lower Oleum menthae 30kg, essence 20kg, the Borneolum Syntheticum 5kg of dropping into, stirring is dissolved Borneolum Syntheticum fully and is obtained solution A.
Get embodiment 1 Chinese medicine extraction liquid 620kg, stir lower efficient solubilizing agents 55kg, Radix Ginseng extractive solution 50kg, the glycerol 20kg of slowly dropping into, fully stirring and evenly mixing obtains solution B.
After solution A and solution B fully mixed, add purified water 100kg and stir.
Through after the assay was approved, the antibacterial foot bath liquid of clearly soothing the spirit of Chinese medicine is made in fill.
Embodiment 3
Take by weighing ethanol 130kg, stir lower Oleum menthae 25kg, essence 15kg, the Borneolum Syntheticum 8kg of dropping into, stirring is dissolved Borneolum Syntheticum fully and is obtained solution A.
Get embodiment 1 Chinese medicine extraction liquid 650kg, stir lower tween 80 40kg, efficient solubilizing agents 30kg, Radix Ginseng extractive solution 10kg, the glycerol 40kg of slowly dropping into, fully stirring and evenly mixing obtains solution B.
After solution A and solution B fully mixed, add purified water 52kg and stir.
Through after the assay was approved, the antibacterial foot bath liquid of clearly soothing the spirit of Chinese medicine is made in fill.
Embodiment 4
Take by weighing ethanol 100kg, stir lower Oleum menthae 20kg, essence 10kg, the Borneolum Syntheticum 10kg of dropping into, stirring is dissolved Borneolum Syntheticum fully and is obtained solution A.
Get embodiment 1 Chinese medicine extraction liquid 700kg, stir lower Arlacel-80 40kg, efficient solubilizing agents 40kg, Radix Ginseng extractive solution 10kg, the glycerol 30kg of slowly dropping into, fully stirring and evenly mixing obtains solution B.
After solution A and solution B fully mixed, add purified water 50kg and stir.
Through after the assay was approved, the antibacterial foot bath liquid of clearly soothing the spirit of Chinese medicine is made in fill.