CN103070691B - Method for manifesting latent fingerprints on basis of fluorescent gold nanoclusters - Google Patents
Method for manifesting latent fingerprints on basis of fluorescent gold nanoclusters Download PDFInfo
- Publication number
- CN103070691B CN103070691B CN201210443554.XA CN201210443554A CN103070691B CN 103070691 B CN103070691 B CN 103070691B CN 201210443554 A CN201210443554 A CN 201210443554A CN 103070691 B CN103070691 B CN 103070691B
- Authority
- CN
- China
- Prior art keywords
- laten fingerprints
- solution
- gold nanoclusters
- manifesting
- glutathione
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Landscapes
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
The invention provides a method for manifesting latent fingerprints on the basis of fluorescent gold nanoclusters, belonging to the field of nano materials. A glutathione solution is taken to be mixed with chloroauric acid solution; a gold nanocluster solution with a fluorescent characteristic, which is used for functionalizing glutathione, is dripped on the surfaces of sweat and blood latent fingerprints to serve as a manifestation material to manifest the sweat and blood latent fingerprints; gold nanocluster particles are absorbed in fingerprint ridgelines; and under the irradiation of an ultraviolet light source, the gold nanocluster particles emit orange fluorescent light, so that the fingerprint ridgelines can be clearly contrasted and distinguished and the aim of manifesting the latent fingerprints by using the fluorescent light is achieved. The method provided by the invention has the advantages of simplicity, sensitivity and no toxicity, the latent fingerprints can be manifested without influencing DNA (deoxyribonucleic acid) components of blood, and the research and application range of manifesting the latent fingerprints by using a fluorescent probe is widened.
Description
Technical field
The invention belongs to detection technique field, be specifically related to utilize the gold nanoclusters with photoluminescent property to manifest the method for laten fingerprints.
Background technology
Fingerprint identification is one of the most reliable method of carrying out individual identification, and fingerprint, in forensic science and criminal suit process, plays important evidential function, and in forensic science development history, fingerprint have the king's of evidence laudatory title.Being applied at present the method that fingerprint on site manifests mainly contains: optics appearance method, physics appearance method and chemical appearance method.The common weakness of these methods is that sensitivity is low, after the method application wherein having, the sensitivity of DNA tests and result is produced to interference.Wherein most widely used method is powder method, but just larger to professional and technical personnel's physical impairment, and the deadly defect of this method is to manifest outmoded fingerprint.Fluorescent appear method has special advantage, can some differentiate the laten fingerprints of unconspicuous background surface, and the produced simultaneously background fluorescence of luminescence generated by light technology using is at present very large to the interference of conventional luminescence generated by light Bio-imprinting identification, and difficulty reaches the requirement of expection.For this reason, Background suppression fluorescence becomes the key that improves Bio-imprinting recognition effect, and in addition, in dark substrate surface, strong background substrate, manifesting of laten fingerprints is also one of knotty problem.In recent years, utilize semiconductor nano CdSe, CdS etc. as luciferase assay reagent, to detect the report more [1-5] of laten fingerprints, but because Cd is heavy metal, harmful to human health, in synthetic process, and in using operating process, all likely experimenter and technical staff are worked the mischief, therefore without the research and development that poison with the on-the-spot Bio-imprinting appearing technique of high sensitivity, become the emphasis of forensic science research and countries in the world Forensic Science personnel's striving direction.
Gold nano grain, owing to thering is the character of surface plasma body resonant vibration, gold nano grain presents different colors with the variation of particle diameter, and have that preparation is simple, particle diameter evenly, strong, the good biocompatibility of stable chemical nature, affinity, be easy to the advantages such as the fixing modification of biomolecule, can improve the sensitivity that Bio-imprinting manifests.At present, metal nanoparticle has successfully been applied to, in the diagnosis and treatment of various nano biological sensors and disease, have huge application prospect in biomolecule detection and sensing.In addition, research is found progressively to reduce along with the size of metal material, until during Nano grade, the luminous efficiency of metal has obvious enhancing, particularly when its size approaches the rank (being less than 1nm) of Fermi's wavelength of electronics [6], noble-metal nanoclusters (as gold, silver) can present stronger photoluminescent property [7-10].Luminous metal nanometre cluster has the character that is much better than traditional fluorogen, as little in size, good light stability, and large Stokes displacement etc., at unimolecule spectrum, fluorescence imaging, has considerable application prospect on photoelectric device.With traditional semiconductor nano quantum dot (as CdS, CdSe and CdTe) compare, not only there is strong photoluminescent property, go back safety non-toxic, this makes fluorogold nano-particle become desirable fluorescence labeling material, can be widely used in waiting in detection [11] in organism.At present, utilize its research to other human body legacy recognition detection and the existing field investigation of crime not yet to have report.
Based on nonhazardous, highly sensitive front topic, we plan to have the epipolic nano-particle of high strength and are developed as the nanometer that manifests laten fingerprints and manifest probe material, detect and manifest laten fingerprints.
List of references:
[1]?Y.F.?Wang,?R.Q.?Yang,?Y.J.?Wang,?Z.X.?Shi,?J.J.?Liu,?
Forensic?Sci.
?Int.
,?
2009,?185,?96.
[2]?F.?Gao,?J.X.?Han,?J.?Zhang,?Q.?Li,?X.F.?Sun,?J.C.?Zheng,?L.R.?Bao,?X.?Li,?Z.L.?Liu,?
Nanotechnology,2011
,?22,?075705.
[3]?A.?Becue,?S.?Moret,?C.Champod,?P.?Margot,?
Forensic?Sci.
?Int.
,?
2009,?191,?36.
[4]?J.J?Liu,?Z.X.?Shi,?Y.C.?Yu,?R.Q.?Yang,?S.L.?Zuo,?
J.
?Colloid.?
Int.
?Sci.?2010,?342,?278.
[5]?Y.?J.?Jin,?Y.J.?Luo,?G.P.?Li,?J.?Li,?Y.F.?Wang,?R.Q.?Yang,?W.T.?Lu,?
Forensic?Sci.
?Int.
,?
2008,?179,?34.
[6]?Haberland?H,?Clusters?of?Atoms?and?Molecules:?Theory?Experiment,?and?Clusters?of?Atoms.?
Berlin:?Springer-Verlag ;?
1994.
[7]?Huang?C?C,?Liao?H?Y,?Shiang?Y?C,?
J.?Mater.?Chem.2009,?19,?755.
[8]?Yu?J,?Patel?S?A,?Dickson?R?M,?
Angew.?Chem.?Int.?Ed.?2007,?46,?2028.
[9]?Gwinn?E?G,?O’Neill?P,?Guerrero?A?J,
?Adv.?Mater.2008,?20,?279.
[10]?Sengupta?B,?Ritchie?C?M,?Buckman?J?G,?
J.?Phys.?Chem.?C,?2008
,?112,?18776.
[11]?Liu?S?H,?Lu?F,?Zhu?J?J,?
Chem.?Commun. ,?
2011,?47,?2661.
Summary of the invention
The object of this invention is to provide a kind of method of utilizing fluorescent appear laten fingerprints, with thering is hyperfluorescence character gold nanoclusters, as manifesting material, manifest laten fingerprints.
The tripeptides that glutathione (GSH) is comprised of glutamic acid, cysteine and glycine, glutathione is containing active sulfydryl (-SH).Glutathione can be used as reducing agent gold chloride is reduced, generate the glutathione functional fluorescence gold nanoclusters (GSH-Au) of size within the scope of 2-3nm, at wavelength, be that 395nm place excites, at 610nm, obtain maximum emission peak, under uviol lamp (ripple is 365nm) irradiates, the aqueous solution of the fluorogold nano-cluster (GSH-Au) of glutathione functionalization is sent out orange-colored light.(J. Zheng, PhD Dissertation, Georgia Institute of Technology, 2005. Cheng-Tai Chen, Wei-Jen Chen, Chao-Zong Liu, Ling-Ya Chang, Yu-Chie Chen, Chem. Commun., 2009,7515 – 7517.) because glutathione is the composition producing in plant, having antioxidation, remove the functions such as free radical, removing toxic substances, is important functional factor, and in food, medicine, application is very extensive; And gold nano grain has good biocompatibility, therefore two kinds of compositions are all green healths, using the fluorogold nano-cluster (GSH-Au) of glutathione functionalization with hyperfluorescence character as reagent, be used for manifesting laten fingerprints, not only there is at present conventional fluorescent material as the hyperfluorescence character of quantum dot, the more important thing is, the fluorogold nano-cluster (GSH-Au) of glutathione functionalization has no side effect, also environmental protection, no matter in preparation or use procedure, all nontoxic harmless, be desirable developing latent finger prints using material.The invention provides and utilize the fluorogold nano-cluster (GSH-Au) of glutathione functionalization as fluorescent appear material, manifest the method for laten fingerprints.
Fluorogold nano-cluster for the method for developing latent finger prints using, be specifically related to glutathione functionalization gold nanoclusters preparation and manifesting an application for laten fingerprints, detailed process is as follows:
1, the preparation of the gold nanoclusters of glutathione functionalization:
The gold nanoclusters with photoluminescent property of preparing glutathione functionalization according to literature method, glutathione is mixed with to the solution for standby of 2.5-5 mM/L, gold chloride is mixed with in darkroom to the solution for standby of 2.5-5 mM/L, get the 2.5 mM/L glutathione solution of 5ml and the 2.5 μ M/L chlorauric acid solutions of 5ml mix under the condition of shading, in temperature, be at the uniform velocity to stir in the water-bath of 32-37 C, under normal daylight, isothermal reaction 36-72 hour, the solution obtaining is removed unreacted glutathione through centrifugal, just obtain the gold nanoclusters aqueous solution of glutathione functionalization, under ultraviolet source, present strong fluorescent red-orange, solution saves backup under the condition of 4 C.
2, the gold nanoclusters solution of glutathione functionalization is used for manifesting of laten fingerprints:
To point and press on surfaces such as glass, silicon chips, finger leaves potential trace on surfaces such as glass, silicon chips, obtain perspiration laten fingerprints sample, finger is first dipped in the solution after hemodilution 20-100 times, moistening and the dripless of finger surface, then by surfaces such as glass, silicon chips, point and leave potential trace on surfaces such as glass, silicon chips, obtain blood laten fingerprints sample.While manifesting laten fingerprints, by after the gold nanoclusters solution dilution 10-20 of glutathione functionalization times, take a morsel and drop in perspiration, the surface of blood laten fingerprints, after 15-20 minute, gold nanoclusters solution is at glass, the upper evaporation in the surface such as silicon chip, leave dry trace, due to the composition effect in gold nanoclusters solution and laten fingerprints perspiration, gold nanoclusters granule is attracted in fingerprint ridge, after gold nanoclusters solution is dry, the gold nanoclusters granule of fingerprint ridge part is more, under the irradiation of ultraviolet source, gold nanoclusters granule sends fluorescent orange, can clearly contrast the stricture of vagina line of telling fingerprint, thereby reach the object of fluorescent appear laten fingerprints.
Utilize fluorogold nano-cluster to manifest laten fingerprints except manifesting the laten fingerprints on common object surface as reagent, can also manifest the laten fingerprints of the unconspicuous dark substrate surface of some contrasts, moist surface.
Tool of the present invention has the following advantages:
1, sensitive height, quick, easy to operate.
2, synthetic, testing process is without any side effects.
3, do not destroy the potential information of laten fingerprints, the DNA that does not affect laten fingerprints identifies.
Accompanying drawing explanation
The fluorescence spectrum figure of accompanying drawing 1, fluorogold nano-cluster;
Accompanying drawing 2, fluorogold nano-cluster manifest laten fingerprints.
The specific embodiment
embodiment 1
Utilize the gold nanoclusters of glutathione functionalization to manifest perspiration laten fingerprints
1, the preparation of the gold nanoclusters of glutathione functionalization:
The gold nanoclusters with photoluminescent property of preparing glutathione functionalization according to literature method, glutathione is mixed with to the solution for standby of 2.5mM/L, gold chloride is mixed with in darkroom to the solution for standby of 2.5 mM/L, the 2.5 mM/L glutathione solution of getting 5ml mix under the condition of shading with the 2.5 mM/L chlorauric acid solutions of 5ml, in temperature, be at the uniform velocity to stir in the water-bath of 32 C, under normal daylight, isothermal reaction 36 hours, the solution obtaining is removed unreacted glutathione through centrifugal, just obtain the gold nanoclusters aqueous solution of glutathione functionalization, under ultraviolet source, present strong fluorescent red-orange, solution saves backup under the condition of 4 C.
2, the gold nanoclusters solution of glutathione functionalization is used for manifesting of laten fingerprints:
To point and press at glass, the surfaces such as silicon chip, finger is at glass, the surfaces such as silicon chip leave potential trace, obtain perspiration laten fingerprints sample, by after 10 times of the gold nanoclusters solution dilutions of glutathione functionalization, with dropper, take a morsel and drip the surface that 3-5 drops in perspiration laten fingerprints, after 15 minutes, gold nanoclusters solution is at glass, the upper evaporation in the surface such as silicon chip, leave dry trace, due to the composition effect in gold nanoclusters solution and laten fingerprints perspiration, gold nanoclusters granule is attracted in fingerprint ridge, after gold nanoclusters solution is dry, the gold nanoclusters granule of fingerprint ridge part is more, under the irradiation of ultraviolet source, gold nanoclusters granule sends fluorescent orange, can clearly contrast the stricture of vagina line of telling fingerprint, thereby reach the object of fluorescent appear laten fingerprints.
embodiment 2
Utilize the gold nanoclusters of glutathione functionalization to manifest blood laten fingerprints
1, the preparation of the gold nanoclusters of glutathione functionalization:
The gold nanoclusters with photoluminescent property of preparing glutathione functionalization according to literature method, glutathione is mixed with to the solution for standby of 5 mM/L, gold chloride is mixed with in darkroom to the solution for standby of 5mM/L, the 5mM/L glutathione solution of getting 5ml mixes under the condition of shading with the 5mM/L chlorauric acid solution of 5ml, in temperature, be at the uniform velocity to stir in the water-bath of 37 C, under normal daylight, isothermal reaction 72 hours, the solution obtaining is removed unreacted glutathione through centrifugal, just obtain the gold nanoclusters aqueous solution of glutathione functionalization, under ultraviolet source, present strong fluorescent red-orange, solution saves backup under the condition of 4 C.
2, the gold nanoclusters solution of glutathione functionalization is used for manifesting of blood laten fingerprints:
Finger is first dipped in the solution after hemodilution 20-100 times, moistening and the dripless of finger surface, then press at glass, the surfaces such as silicon chip, finger is at glass, the surfaces such as silicon chip leave potential trace, obtain blood laten fingerprints sample, by after 20 times of the gold nanoclusters solution dilutions of glutathione functionalization, with dropper, take a morsel and drip the surface that 3-5 drops in blood laten fingerprints, after 20 minutes, gold nanoclusters solution is at glass, the upper evaporation in the surface such as silicon chip, leave dry trace, due to the composition effect in gold nanoclusters solution and laten fingerprints blood, gold nanoclusters granule is attracted in fingerprint ridge, after gold nanoclusters solution is dry, the gold nanoclusters granule of fingerprint ridge part is more, under the irradiation of ultraviolet source, gold nanoclusters granule sends fluorescent orange, can clearly contrast the stricture of vagina line of telling fingerprint, thereby reach the object of fluorescent appear blood laten fingerprints.
?
Claims (1)
1. the gold nanoclusters solution of glutathione functionalization is in the application aspect the manifesting of laten fingerprints, it is characterized in that, utilize the gold nanoclusters solution of glutathione functionalization to manifest laten fingerprints as reagent, except manifesting the laten fingerprints on common object surface, the laten fingerprints that can also manifest the unconspicuous dark substrate surface of some contrasts, moist surface, its method step that manifests laten fingerprints is as follows:
To point by glass surface, silicon chip surface, some the unconspicuous dark substrate surface of contrast or moist surfaces, obtain perspiration laten fingerprints sample;
Will finger first at hemodilution 20-100, in the solution after doubly, dip in, the moistening and dripless of finger surface, then by obtaining blood laten fingerprints sample at glass surface, silicon chip surface, some unconspicuous dark substrate surfaces of contrast or moist surface;
While manifesting laten fingerprints, by after the gold nanoclusters solution dilution 10-20 of glutathione functionalization times, take a morsel and drop in the surface of perspiration, blood laten fingerprints, after 15-20 minute, the gold nanoclusters solution of glutathione functionalization evaporates on glass surface, silicon chip surface, some unconspicuous dark substrate surfaces of contrast or moist surface, leave dry trace, can clearly contrast the streakline of telling fingerprint, manifest laten fingerprints.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210443554.XA CN103070691B (en) | 2012-11-09 | 2012-11-09 | Method for manifesting latent fingerprints on basis of fluorescent gold nanoclusters |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201210443554.XA CN103070691B (en) | 2012-11-09 | 2012-11-09 | Method for manifesting latent fingerprints on basis of fluorescent gold nanoclusters |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN103070691A CN103070691A (en) | 2013-05-01 |
| CN103070691B true CN103070691B (en) | 2014-11-05 |
Family
ID=48147546
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201210443554.XA Expired - Fee Related CN103070691B (en) | 2012-11-09 | 2012-11-09 | Method for manifesting latent fingerprints on basis of fluorescent gold nanoclusters |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN103070691B (en) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103431867A (en) * | 2013-08-20 | 2013-12-11 | 北京科技大学 | Method for displaying latent fingerprints on fluorogold nano-cluster protected by protein |
| CN106662580B (en) * | 2014-08-06 | 2018-11-27 | 健康与环境慕尼黑德国研究中心赫姆霍茨中心（有限责任公司） | Test and analyze newly clustering for object |
| TWI530674B (en) * | 2014-11-06 | 2016-04-21 | 財團法人工業技術研究院 | Gold nanocluster composition and method for preparing the same and method for detecting thiol-containing compounds |
| CN105907389B (en) * | 2016-05-03 | 2018-03-27 | 西南政法大学 | Noble-metal nanoclusters show the preparation of reagent and show the method for Sweat latent fingerprint |
| CN107362370B (en) * | 2016-05-13 | 2022-07-26 | 国家纳米科学中心 | Method for treating pancreatic cancer based on combination of gold nanoclusters and NGF siRNA |
| CN106037754B (en) * | 2016-05-27 | 2018-12-04 | 江南大学 | A kind of method of the latent fingerprint of visual carburetion |
| CN106085420B (en) * | 2016-06-02 | 2018-02-16 | 中国石油大学(华东) | A kind of peptide modified gold nanoclusters and preparation method thereof |
| CN106010513B (en) * | 2016-06-02 | 2018-02-16 | 中国石油大学(华东) | A kind of gold nanoclusters peptide modified KCK and preparation method thereof |
| CN107971481B (en) * | 2016-10-21 | 2022-01-25 | 国家纳米科学中心 | Gold nanocluster with antibacterial activity and preparation method and application thereof |
| CN106891016A (en) * | 2017-01-10 | 2017-06-27 | 青岛科技大学 | A kind of preparation of fluorescence silver nanoclusters and its method for manifesting latent fingerprint |
| CN106865615B (en) * | 2017-02-14 | 2018-05-15 | 西南政法大学 | A kind of preparation of copper/chromium composite black nanometer powder and its finger mark process for show |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101004388A (en) * | 2007-01-23 | 2007-07-25 | 吉林大学 | Method for showing latent fingerprint, and develop system |
| CN101703404A (en) * | 2009-08-28 | 2010-05-12 | 东北师范大学 | Method for showing fingerprints on various object surfaces and keeping DNA information |
| CN101792147A (en) * | 2010-01-12 | 2010-08-04 | 清华大学深圳研究生院 | Surface modification method of silica particles and method for displaying latent fingerprints |
-
2012
- 2012-11-09 CN CN201210443554.XA patent/CN103070691B/en not_active Expired - Fee Related
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101004388A (en) * | 2007-01-23 | 2007-07-25 | 吉林大学 | Method for showing latent fingerprint, and develop system |
| CN101703404A (en) * | 2009-08-28 | 2010-05-12 | 东北师范大学 | Method for showing fingerprints on various object surfaces and keeping DNA information |
| CN101792147A (en) * | 2010-01-12 | 2010-08-04 | 清华大学深圳研究生院 | Surface modification method of silica particles and method for displaying latent fingerprints |
Non-Patent Citations (6)
| Title |
|---|
| Application of photoluminescent CdS/PAMAM nanocomposites in fingerprint detection;Yu-Juan Jin,et al.;《Forensic Science International》;20080731;第179卷(第1期);34-38 * |
| Cheng-Tai Chen,et al..Glutathione-bound gold nanoclusters for selective-bingding and detection of glutathione S-transferase-fusion proteins from cell lysates.《Chemical Communications》.2009,(第48期),7515-7517. * |
| Yuan Feng Wang ,et al..Application of CdSe nanoparticle suspension for developing latent fingermarks on the sticky side of adhesives.《Forensic Science International》.2009,第185卷(第1-3期),96-99. * |
| Yuan Feng Wang,et al..Application of CdSe nanoparticle suspension for developing latent fingermarks on the sticky side of adhesives.《Forensic Science International》.2009,第185卷(第1-3期),96-99. * |
| Yu-Juan Jin,et al..Application of photoluminescent CdS/PAMAM nanocomposites in fingerprint detection.《Forensic Science International》.2008,第179卷(第1期),34-38. * |
| 陈艳，等..潜指纹显现方法研究进展.《应用化学》.2011,第28卷(第10期),1099-1107. * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103070691A (en) | 2013-05-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103070691B (en) | Method for manifesting latent fingerprints on basis of fluorescent gold nanoclusters | |
| Wang et al. | Recent progress in background-free latent fingerprint imaging | |
| Wang et al. | Facile synthesis of novel carbon quantum dots from biomass waste for highly sensitive detection of iron ions | |
| Xu et al. | Fast imaging of eccrine latent fingerprints with nontoxic Mn-doped ZnS QDs | |
| Lee et al. | Nanoparticle size detection limits by single particle ICP-MS for 40 elements | |
| Li et al. | Europium functionalized ratiometric fluorescent transducer silicon nanoparticles based on FRET for the highly sensitive detection of tetracycline | |
| CN108913132A (en) | A kind of preparation method and its product of double transmitting carbon-based nano probes | |
| CN103115905B (en) | A kind of fluorescent detection probe of lead ion | |
| CN106974659A (en) | A kind of latent fingerprint detection method based on red fluorescence carbon point material | |
| Xiao et al. | Fluorescent carbon dots: facile synthesis at room temperature and its application for Fe 2+ sensing | |
| CN105907389B (en) | Noble-metal nanoclusters show the preparation of reagent and show the method for Sweat latent fingerprint | |
| Li et al. | A label-free turn-on-off fluorescent sensor for the sensitive detection of cysteine via blocking the Ag+-enhancing glutathione-capped gold nanoclusters | |
| Luo et al. | Glutathione‐stabilized Cu nanocluster‐based fluorescent probe for sensitive and selective detection of Hg2+ in water | |
| CN106153594A (en) | Surface enhanced raman spectroscopy detection adhesive tape, its preparation method and application | |
| Cleary et al. | Chiral and luminescent TiO2 nanoparticles | |
| JPWO2014181814A1 (en) | Biochip for Raman quantitative analysis of biological samples | |
| RU2014120749A (en) | CHEMICAL SENSOR, CHEMICAL SENSOR MODULE, CHEMICAL MATTER DETECTION DEVICE AND CHEMICAL DETECTION METHOD | |
| CN110530950A (en) | The building of paper base sensor based on exciton Plasma Interaction efficient detection PSA | |
| CN106010512B (en) | One kind being used for Hg2+The SiO of detection2/ Au nanocomposites and preparation method thereof | |
| Fu et al. | Photoluminescence enhancement of silver nanoclusters assembled on the layered double hydroxides and their application to guanine detection | |
| CN108732151B (en) | Preparation of luminescent gold nanoparticles with high-sensitivity optical response to volatile amine and rapid analysis and detection method thereof | |
| Huy et al. | Photoluminescence spectroscopy of Cd-based quantum dots for optosensing biochemical molecules | |
| CN109781704A (en) | A kind of magnetic surface enhancing Raman spectrum active substrate and the preparation method and application thereof | |
| Chen et al. | N-doped carbon dots as the multifunctional fluorescent probe for mercury ion, glutathione and pH detection | |
| CN107436301A (en) | A kind of 2,6 chlorophenesic acid trace sensors based on surface enhanced Raman technique and its production and use |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20141105 Termination date: 20161109 |
|
| CF01 | Termination of patent right due to non-payment of annual fee |